The recent development of messenger RNA (mRNA) vaccines for COVID-19 has highlighted the potential of mRNA technology for gene therapy. However, mRNA is inherently unstable and vulnerable to degradation by nucleases and other cellular enzymes. This proposal aims to investigate the potential of a novel class of nanocoatings for mRNA protection and delivery in gene therapy.
Advanced materials | Bioactive materials | Nanobiotechnology
This project is interdisciplinary in nature, having bridging between material science, nanotechnology, biomedical science, and chemical engineering. The Taste of Research candidate will have the opportunity to interact with a multidisciplinary team of researchers and to learn nanomaterial research frontiers.
This project will contribute to developing a novel class of nanoparticles for gene therapy. Potential high impact journal publications are expected from this project.