Age-related macular degeneration (AMD) is a leading cause of vision loss in the elderly population. The molecular mechanisms driving AMD pathogenesis are yet to be fully elucidated. This PhD project is focused on characterising the metabolic and mitochondrial dysfunctions driving AMD pathogenesis.
This project will leverage established AMD patient biobanks of induced pluripotent stem cell-derived retinal pigment epithelial cells and retinal endothelial cells.
This project will use cutting-edge molecular biology techniques including examining the bioenergetic profiles of retinal cells, evaluating the role of oxidative stress and assessing mitochondrial ultrastructural morphology. Novel drugs that enhance mitochondrial function will be tested in iPS-RPE derived from AMD patients to restore normal function.
How to Apply
Express your interest in this project by emailing Dr Daisy Shu at daisy.shu@unsw.edu.au with a copy of your CV and your academic transcript(s).
If you are shortlisted, you will be asked to submit a formal application for admission to the PhD program.
School / Research Area
Optometry and Vision Science
- Overview
- News
- Our team
- References
