Dr Adam Hill

Pineda S; Nikolova-Krstevski V; Leimena C; Atkinson AJ; Altekoester AK; Cox CD; Jacoby A; Huttner IG; Ju YK; Soka M; Ohanian M; Trivedi G; Kalvakuri S; Birker K; Johnson R; Molenaar P; Kuchar D; Allen DG; Van Helden DF; Harvey RP; Hill AP; Bodmer R; Vogler G; Dobrzynski H; Ocorr K; Fatkin D, 2021, 'Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, KCa1.1, in Sinus Node Function and Arrhythmia Risk', Circulation: Genomic and Precision Medicine, pp. 230 - 242, http://dx.doi.org/10.1161/CIRCGEN.120.003144

Ng CA; Farr J; Young P; Windley MJ; Perry MD; Hill AP; Vandenberg JI, 2021, 'Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-Throughput automated patch clamp electrophysiology', Biology Methods and Protocols, vol. 6, pp. bpab003, http://dx.doi.org/10.1093/biomethods/bpab003

Heitmann S; Shpak A; Vandenberg JI; Hill AP, 2021, 'Arrhythmogenic effects of ultra-long and bistable cardiac action potentials', PLoS Computational Biology, vol. 17, http://dx.doi.org/10.1371/JOURNAL.PCBI.1008683

Li Z; Mirams GR; Yoshinaga T; Ridder BJ; Han X; Chen JE; Stockbridge NL; Wisialowski TA; Damiano B; Severi S; Morissette P; Kowey PR; Holbrook M; Smith G; Rasmusson RL; Liu M; Song Z; Qu Z; Leishman DJ; Steidl-Nichols J; Rodriguez B; Bueno-Orovio A; Zhou X; Passini E; Edwards AG; Morotti S; Ni H; Grandi E; Clancy CE; Vandenberg J; Hill A; Nakamura M; Singer T; Polonchuk L; Greiter-Wilke A; Wang K; Nave S; Fullerton A; Sobie EA; Paci M; Musuamba Tshinanu F; Strauss DG, 2020, 'General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico Strategy', Clinical Pharmacology and Therapeutics, vol. 107, pp. 102 - 111, http://dx.doi.org/10.1002/cpt.1647

Perry MD; Ng CA; Mangala MM; Ng TYM; Hines AD; Liang W; Xu MJO; Hill AP; Vandenberg JI, 2020, 'Pharmacological activation of IKrin models of long QT Type 2 risks overcorrection of repolarization', Cardiovascular Research, vol. 116, pp. 1434 - 1445, http://dx.doi.org/10.1093/cvr/cvz247

Ng CA; Perry MD; Liang W; Smith NJ; Foo B; Shrier A; Lukacs GL; Hill AP; Vandenberg JI, 2020, 'High-throughput phenotyping of heteromeric human ether-à-go-go-related gene potassium channel variants can discriminate pathogenic from rare benign variants', Heart Rhythm, vol. 17, pp. 492 - 500, http://dx.doi.org/10.1016/j.hrthm.2019.09.020

Black KA; He S; Jin R; Miller DM; Bolla JR; Clarke OB; Johnson P; Windley M; Burns CJ; Hill AP; Laver D; Robinson CV; Smith BJ; Gulbis JM, 2020, 'A constricted opening in Kir channels does not impede potassium conduction', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-020-16842-0

Ballouz S; Mangala MM; Perry MD; Heitmann S; Gillis JA; Hill AP; Vandenberg JI, 2021, 'Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events', Cardiovascular Research, vol. 117, pp. 2216 - 2227, http://dx.doi.org/10.1093/cvr/cvaa280

Lei CL; Fabbri A; Whittaker DG; Clerx M; Windley MJ; Hill AP; Mirams GR; de Boer TP, 2020, 'A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer', Wellcome Open Research, vol. 5, pp. 152 - 152, http://dx.doi.org/10.12688/wellcomeopenres.15968.1

Lee W; Windley MJ; Perry MD; Vandenberg JI; Hill AP, 2019, 'Protocol-dependent differences in IC50 values measured in human ether-á-go-go–related gene assays occur in a predictable way and can be used to quantify state preference of drug binding', Molecular Pharmacology, vol. 95, pp. 537 - 550, http://dx.doi.org/10.1124/mol.118.115220

Hill AP, 2019, 'Introduction to the Australian Society for Biophysics', Biophysical Reviews, vol. 11, pp. 253 - 254, http://dx.doi.org/10.1007/s12551-019-00519-0

Tardo D; Peck M; Hill A; Vandenberg J, 2019, 'T Wave Morphology Biomarkers in Congenital and Acquired Long QT Syndrome', Heart, Lung and Circulation, vol. 28, pp. S229 - S229, http://dx.doi.org/10.1016/j.hlc.2019.06.223

Windley MJ; Lee W; Vandenberg JI; Hill AP, 2018, 'The temperature dependence of kinetics associated with drug block of hERG channels is compound-specific and an important factor for proarrhythmic risk prediction', Molecular Pharmacology, vol. 94, pp. 760 - 769, http://dx.doi.org/10.1124/mol.117.111534

Beattie KA; Hill AP; Bardenet R; Cui Y; Vandenberg JI; Gavaghan DJ; de Boer TP; Mirams GR, 2018, 'Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics', Journal of Physiology, vol. 596, pp. 1813 - 1828, http://dx.doi.org/10.1113/JP275733

Holliday M; Ross SB; Lim S; Mangala M; Hill A; Szappanos HC; Hool L; Semsarian C, 2018, 'Development of induced pluripotent stem cells from a patient with hypertrophic cardiomyopathy who carries the pathogenic myosin heavy chain 7 mutation p.Arg403Gln', Stem Cell Research, vol. 33, pp. 269 - 273, http://dx.doi.org/10.1016/j.scr.2018.11.011

Munawar S; Windley MJ; Tse EG; Todd MH; Hill AP; Vandenberg JI; Jabeen I, 2018, 'Experimentally validated pharmacoinformatics approach to predict hERG inhibition potential of new chemical entities', Frontiers in Pharmacology, vol. 9, http://dx.doi.org/10.3389/fphar.2018.01035

Lee W; Mangala M; Windley M; Perry M; Vandenberg J; Hill A, 2018, 'Novel Pre–Clinical Risk Prediction of Acquired Long QT Syndrome', Heart, Lung and Circulation, vol. 27, pp. S180 - S180, http://dx.doi.org/10.1016/j.hlc.2018.06.309

Nikolova-Krstevski V; Wagner S; Yu ZY; Cox CD; Cvetkovska J; Hill AP; Huttner IG; Benson V; Werdich AA; MacRae C; Feneley MP; Friedrich O; Martinac B; Fatkin D, 2017, 'Endocardial TRPC-6 Channels Act as Atrial Mechanosensors and Load-Dependent Modulators of Endocardial/Myocardial Cross-Talk', JACC: Basic to Translational Science, vol. 2, pp. 575 - 590, http://dx.doi.org/10.1016/j.jacbts.2017.05.006

Lee W; Windley MJ; Vandenberg JI; Hill AP, 2017, 'In vitro and in silico risk assessment in acquired long QT syndrome: The devil is in the details', Frontiers in Physiology, vol. 8, http://dx.doi.org/10.3389/fphys.2017.00934

Bavi N; Bavi O; Vossoughi M; Naghdabadi R; Hill AP; Martinac B; Jamali Y, 2017, 'Nanomechanical properties of MscL α helices: A steered molecular dynamics study', Channels, vol. 11, pp. 209 - 223, http://dx.doi.org/10.1080/19336950.2016.1249077

Bavi N; Martinac AD; Cortes DM; Bavi O; Ridone P; Nomura T; Hill AP; Martinac B; Perozo E, 2017, 'Structural Dynamics of the MscL C-terminal Domain', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/s41598-017-17396-w

Windley MJ; Abi-Gerges N; Fermini B; Hancox JC; Vandenberg JI; Hill AP, 2017, 'Measuring kinetics and potency of hERG block for CiPA', Journal of Pharmacological and Toxicological Methods, vol. 87, pp. 99 - 107, http://dx.doi.org/10.1016/j.vascn.2017.02.017

Vandenberg JI; Perry MD; Hill AP, 2017, 'Recent advances in understanding and prevention of sudden cardiac death', F1000Research, vol. 6, http://dx.doi.org/10.12688/f1000research.11855.1

Hill AP, 2017, 'Boosting the reserves: additive regulation of cardiac repolarisation', Journal of Physiology, vol. 595, pp. 2269 - 2270, http://dx.doi.org/10.1113/JP273940

Immanuel SA; Sadrieh A; Baumert M; Couderc JP; Zareba W; Hill AP; Vandenberg JI, 2016, 'T-wave morphology can distinguish healthy controls from LQTS patients', Physiological Measurement, vol. 37, pp. 1456 - 1473, http://dx.doi.org/10.1088/0967-3334/37/9/1456

Hodkinson EC; Neijts M; Sadrieh A; Imtiaz MS; Baumert M; Subbiah RN; Hayward CS; Boomsma D; Willemsen G; Vandenberg JI; Hill AP; De Geus E, 2016, 'Heritability of ECG biomarkers in the Netherlands twin registry measured from Holter ECGs', Frontiers in Physiology, vol. 7, http://dx.doi.org/10.3389/fphys.2016.00154

Windley MJ; Mann SA; Vandenberg JI; Hill AP, 2016, 'Temperature effects on kinetics of KV11.1 drug block have important consequences for in silico proarrhythmic risk prediction', Molecular Pharmacology, vol. 90, pp. 1 - 11, http://dx.doi.org/10.1124/mol.115.103127

Lee W; Mann SA; Windley MJ; Imtiaz MS; Vandenberg JI; Hill AP, 2016, 'In silico assessment of kinetics and state dependent binding properties of drugs causing acquired LQTS', Progress in Biophysics and Molecular Biology, vol. 120, pp. 89 - 99, http://dx.doi.org/10.1016/j.pbiomolbio.2015.12.005

Bavi N; Cortes DM; Cox CD; Rohde PR; Liu W; Deitmer JW; Bavi O; Strop P; Hill AP; Rees D; Corry B; Perozo E; Martinac B, 2016, 'The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels', Nature Communications, vol. 7, http://dx.doi.org/10.1038/ncomms11984

Hill AP; Perry MD; Abi-Gerges N; Couderc JP; Fermini B; Hancox JC; Knollmann BC; Mirams GR; Skinner J; Zareba W; Vandenberg JI, 2016, 'Computational cardiology and risk stratification for sudden cardiac death: one of the grand challenges for cardiology in the 21st century', Journal of Physiology, vol. 594, pp. 6893 - 6908, http://dx.doi.org/10.1113/JP272015

Mann SA; Imtiaz M; Winbo A; Rydberg A; Perry MD; Couderc JP; Polonsky B; McNitt S; Zareba W; Hill AP; Vandenberg JI, 2016, 'Convergence of models of human ventricular myocyte electrophysiology after global optimization to recapitulate clinical long QT phenotypes', Journal of Molecular and Cellular Cardiology, vol. 100, pp. 25 - 34, http://dx.doi.org/10.1016/j.yjmcc.2016.09.011

Perry MD; Ng CA; Phan K; David E; Steer K; Hunter MJ; Mann SA; Imtiaz M; Hill AP; Ke Y; Vandenberg JI, 2016, 'Rescue of protein expression defects may not be enough to abolish the pro-arrhythmic phenotype of long QT type 2 mutations', Journal of Physiology, vol. 594, pp. 4031 - 4049, http://dx.doi.org/10.1113/JP271805

Immanuel S; Sadrieh A; Baumert M; Couderc J; Zareba W; Hill A; Vandenberg J, 2016, 'T Wave Morphology Can Distinguish Healthy Controls From LQTS Patients With Normal QT Intervals', Heart, Lung and Circulation, vol. 25, pp. S262 - S262, http://dx.doi.org/10.1016/j.hlc.2016.06.610

Chaudhuri R; Sadrieh A; Hoffman NJ; Parker BL; Humphrey SJ; Stöckli J; Hill AP; James DE; Yang JYH, 2015, 'PhosphOrtholog: A web-based tool for cross-species mapping of orthologous protein post-translational modifications', BMC Genomics, vol. 16, http://dx.doi.org/10.1186/s12864-015-1820-x

Perry MD; Ng CA; Mann SA; Sadrieh A; Imtiaz M; Hill AP; Vandenberg JI, 2015, 'Getting to the heart of hERG K⁺ channel gating', Journal of Physiology, vol. 593, pp. 2575 - 2585, http://dx.doi.org/10.1113/JP270095

Hill AP; Perrin MJ; Heide J; Campbell TJ; Mann SA; Vandenberg JI, 2014, 'Kinetics of drug interaction with the Kv11.1 potassium channel', Molecular Pharmacology, vol. 85, pp. 769 - 776, http://dx.doi.org/10.1124/mol.114.091835

Ng CA; Phan K; Hill AP; Vandenberg JI; Perry MD, 2014, 'Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels', Journal of Biological Chemistry, vol. 289, pp. 25822 - 25832, http://dx.doi.org/10.1074/jbc.M114.558379

Sadrieh A; Domanski L; Pitt-Francis J; Mann SA; Hodkinson EC; Ng CA; Perry MD; Taylor JA; Gavaghan D; Subbiah RN; Vandenberg JI; Hill AP, 2014, 'Multiscale cardiac modelling reveals the origins of notched T waves in long QT syndrome type 2', Nature Communications, vol. 5, http://dx.doi.org/10.1038/ncomms6069

Hodkinson EC; Hill AP; Vandenberg JI, 2014, 'The Romano-Ward syndrome--1964-2014: 50 years of progress.', Irish medical journal, vol. 107, pp. 122 - 124

Ke Y; Ng CA; Hunter MJ; Mann SA; Heide J; Hill AP; Vandenberg JI, 2013, 'Trafficking defects in PAS domain mutant Kv11.1 channels: Roles of reduced domain stability and altered domain-domain interactions', Biochemical Journal, vol. 454, pp. 69 - 77, http://dx.doi.org/10.1042/BJ20130328

Ng CA; Ke Y; Perry MD; Tan PS; Hill AP; Vandenberg JI, 2013, 'C-Terminal β9-Strand of the Cyclic Nucleotide-Binding Homology Domain Stabilizes Activated States of Kv11.1 Channels', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0077032

Sadrieh A; Mann SA; Subbiah RN; Domanski L; Taylor JA; Vandenberg JI; Hill AP, 2013, 'Quantifying the origins of population variability in cardiac electrical activity through sensitivity analysis of the electrocardiogram', Journal of Physiology, vol. 591, pp. 4207 - 4222, http://dx.doi.org/10.1113/jphysiol.2013.251710

Mann S; Sadrieh A; Subbiah R; Domanski L; Taylor J; Vandenberg J; Hill A, 2013, 'Epistatic Interactions of Ion Channels Underlie Variability in Cardiac Electrical Activity. In-silico Analysis of the Electrocardiogram', Heart, Lung and Circulation, vol. 22, pp. S95 - S96, http://dx.doi.org/10.1016/j.hlc.2013.05.226

Yu Y; Hill AP; McCormick DA, 2012, 'Warm body temperature facilitates energy efficient cortical action potentials', PLoS Computational Biology, vol. 8, http://dx.doi.org/10.1371/journal.pcbi.1002456

Tan PS; Perry MD; Ng C; Vandenberg JI; Hill A, 2012, 'Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels', Journal of General Physiology, vol. 140, pp. 293 - 306, http://dx.doi.org/10.1085/jgp.201110761

Pan D; Hill AP; Kashou A; Wilson KA; Tan-Wilson A, 2011, 'Electrophoretic transfer protein zymography', Analytical Biochemistry, vol. 411, pp. 277 - 283, http://dx.doi.org/10.1016/j.ab.2011.01.015

Wang DT; Hill A; Mann SA; Tan P; Vandenberg JI, 2010, 'Mapping the sequence of conformational changes underlying selectivity filter gating in the K(v)11.1 potassium channel', Nature Structural and Molecular Biology, vol. 18, pp. 35 - 41, http://dx.doi.org/10.1038/nsmb.1966

Clarke O; Caputo A; Hill A; Vandenberg JI; Smith B; Gulbis J, 2010, 'Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels', Cell, vol. 141, pp. 1018 - 1029, http://dx.doi.org/10.1016/j.cell.2010.05.003

Zhao JT; Hill A; Varghese A; Cooper A; Swan H; Laitinen-Forsblom P; Rees M; Skinner J; Campbell TJ; Vandenberg JI, 2009, 'Not all hERG pore domain mutations have a severe phenotype: G584S has an inactivation gating defect with mild phenotype compared to G572S, which has a dominant negative trafficking defect and a severe phenotype', Journal of Cardiovascular Electrophysiology, vol. 20, pp. 923 - 930, http://dx.doi.org/10.1111/j.1540-8167.2009.01468.x

Perrin MJ; Campbell TJ; Hill AP; Vandenberg JI, 2009, 'Insight into Accurate Testing of Drugs which Cause the Acquired Long-QT Syndrome', Heart, Lung and Circulation, vol. 18, pp. S135 - S135, http://dx.doi.org/10.1016/j.hlc.2009.05.306

Perrin MJ; Subbiah RN; Vandenberg JI; Hill A, 2008, 'Human ether-a-go-go related gene (hERG) K+ channels: Function and dysfunction', Progress in Biophysics and Molecular Biology, vol. 98, pp. 137 - 148, http://dx.doi.org/10.1016/j.pbiomolbio.2008.10.006

Hill A; Sunde M; Campbell TJ; Vandenberg JI, 2007, 'Mechanism of block of the hERG K+ channel by the scorpion toxin CnErg1', Biophysical Journal, vol. 92, pp. 3915 - 3929, http://dx.doi.org/10.1529/biophysj.106.101956

Hill A; Campbell TJ; Bansal PS; Kuchel PW; Vandenberg JI, 2007, 'The S631A mutation causes a mechanistic switch in the block of hERG channels by CnErgl', Biophysical Journal, vol. 93, pp. 32 - 34, http://dx.doi.org/10.1529/biophysj.107.114561

Hill A; Sunde M; Vandenberg JI, 2007, 'Mechanisms of block of the hERG K+ channel by the scorpion toxin CnErg1', Biophysical Journal, pp. 124A - 124A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000243972400570&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Clarke CE; Hill A; Kondo M; Subbiah RN; Campbell TJ; Vandenberg JI, 2006, 'Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels', The Journal of Physiology, vol. 573, pp. 291 - 304, http://dx.doi.org/10.1113/jphysiol.2006.108332

Hill AP; Kingston O; Sitsapesan R, 2004, 'Functional regulation of the cardiac ryanodine receptor by suramin and calmodulin involves multiple binding sites', Molecular Pharmacology, vol. 65, pp. 1258 - 1268, http://dx.doi.org/10.1124/mol.65.5.1258

Hill AP; Sitsapesan R, 2002, 'DIDS modifies the conductance, gating, and inactivation mechanisms of the cardiac ryanodine receptor', Biophysical Journal, vol. 82, pp. 3037 - 3047, http://dx.doi.org/10.1016/S0006-3495(02)75644-0

Carriero D; Aberman J; Lin SY; Hill A; Makriyannis A; Salamone JD, 1998, 'A detailed characterization of the effects of four cannabinoid agonists on operant lever pressing', Psychopharmacology, vol. 137, pp. 147 - 156, http://dx.doi.org/10.1007/s002130050604

Pertwee R; Griffin G; Fernando S; Li X; Hill A; Makriyannis A, 1995, 'AM630, a competitive cannabinoid receptor antagonist', Life Sciences, vol. 56, pp. 1949 - 1955, http://dx.doi.org/10.1016/0024-3205(95)00175-6

Ng C-A; Farr J; Young P; Windley MJ; Perry MD; Hill AP; Vandenberg JI, 'Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology', , http://dx.doi.org/10.1101/2021.02.02.427891

Ross S; Holliday M; Lim S; Mangala M; Perry M; Gray B; Fraser S; Hill A; Hudson J; Semsarian C, 2021, 'Functional Analysis of a Novel Heterozygous Variant in CASQ2 as a Distinct Cause of Catecholaminergic Polymorphic Ventricular Tachycardia', Heart, Lung and Circulation, vol. 30, pp. S96 - S96, http://dx.doi.org/10.1016/j.hlc.2021.06.016

Heitmann S; Vandenberg JI; Hill AP, 'Arrhythmogenesis as the failure of repolarization', , http://dx.doi.org/10.1101/2020.07.02.185694

Ng C-A; Ullah R; Farr J; Hill AP; Kozek KA; Vanags LR; Mitchell D; Kroncke BM; Vandenberg JI, 'A Massively Parallel Trafficking Assay Accurately Predicts Loss of Channel Function in KCNH2 Variants', , http://dx.doi.org/10.1101/2021.07.10.451881

Gulbis JM; Miller DM; Black K; Hill AP; Laver D, 2018, 'Can K+ be Conducted through a Narrow Pore? Investigating the role of Conformational Change in Gating Kir Channels', in BIOPHYSICAL JOURNAL, CELL PRESS, San Francisco, CA, Vol. 114, pp. 35A - 35A, presented at 62nd Annual Meeting of the Biophysical-Society, San Francisco, CA, 17 February 2018 - 21 February 2018, http://dx.doi.org/10.1016/j.bpj.2017.11.249

Beattie KA; Bardenet R; Louttit JB; Vandenberg JI; Hill AP; Gavaghan DJ; de Boer TP; Mirams GR, 2017, 'Mathematical Modelling of hERG Channel Kinetics Using Sinusoidal Voltage Protocols', in JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, ELSEVIER SCIENCE INC, Vol. 88, pp. 195 - 196, http://dx.doi.org/10.1016/j.vascn.2017.09.089

Windley M; Abi-Gerges N; Fermini B; Hancox J; Vandenberg J; Hill A, 2017, 'Successes and Challenges of Performing hERG Studies for CiPA', in JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, ELSEVIER SCIENCE INC, pp. 197 - 197, http://dx.doi.org/10.1016/j.vascn.2017.09.095

Windley M; Mann S; Vandenberg J; Hill A, 2017, 'Temperature Effects on Kinetics of hERG Drug Block: Implications for In Silico Proarrhythmic Risk Prediction', in JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, ELSEVIER SCIENCE INC, pp. 203 - 203, http://dx.doi.org/10.1016/j.vascn.2017.09.116

Beattie K; Hill A; Bardenet R; Cui Y; Vandenberg J; Gavaghan D; de Boer T; Mirams G, 2017, Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics, Cold Spring Harbor Laboratory, http://dx.doi.org10.1101/100677

Bavi N; Cox CD; Rohde PR; Hill AP; Corry B; Martinac B, 2016, 'The N-Terminal Helix Acts as a Dynamic Membrane Coupler in the Gating Cycle of the Mechanosensitive Channel MscL', in BIOPHYSICAL JOURNAL, CELL PRESS, Los Angeles, CA, Vol. 110, pp. 116A - 116A, presented at 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, 27 February 2016 - 02 March 2016, http://dx.doi.org/10.1016/j.bpj.2015.11.677

Vandenberg JI; Hill AP, 2016, An 'alternans' way to quantify arrhythmogenic substrates, http://dx.doi.org/10.1113/JP271838

Mann SA; Vandenberg JI; Hill AP, 2016, 'Sudden Infant Death and Modulation of Late Sodium Current by Hypoxia, Investigated in Induced Pluripotent Stem Cells', in BIOPHYSICAL JOURNAL, CELL PRESS, Los Angeles, CA, Vol. 110, pp. 30A - 30A, presented at 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, 27 February 2016 - 02 March 2016, http://dx.doi.org/10.1016/j.bpj.2015.11.227

Hodkinson EC; Hill AP; Vandenberg JI, 2014, The romano-ward syndrome 1964 2014: 50 years of progress, http://dx.doi.org

Hill AP; Mann SA; Imtiaz MS; Perry MD; Vandenberg JI, 2014, 'Using Clinical Datasets to Optimize Models of Human Ventricular Electrophysiology: Implications for In Silico Drug Screening', in BIOPHYSICAL JOURNAL, CELL PRESS, San Francisco, CA, Vol. 112, pp. 465A - 465A, presented at 58th Annual Meeting of the Biophysical-Society, San Francisco, CA, 15 February 2014 - 19 February 2014, http://dx.doi.org/10.1016/j.bpj.2016.11.2493

Sadrieh A; Charissis S; Hill AP, 2013, 'An on-chip heterogeneous implementation of a general sparse linear solver', in Proceedings - IEEE 27th International Parallel and Distributed Processing Symposium Workshops and PhD Forum, IPDPSW 2013, pp. 54 - 63, http://dx.doi.org/10.1109/IPDPSW.2013.51

El-Ajouz S; Hill AP; Gulbis JM; Vandenberg JI, 2013, 'Understanding the Molecular Gates of KirBac3.1', in BIOPHYSICAL JOURNAL, CELL PRESS, Philadelphia, PA, Vol. 104, pp. 128A - 128A, presented at 57th Annual Meeting of the Biophysical-Society, Philadelphia, PA, 02 February 2013 - 06 February 2013, http://dx.doi.org/10.1016/j.bpj.2012.11.737

Tan PS; Perry M; Chai AN; Vandenberg JI; Hill AP, 2012, 'Bimodal Regulation of hERG Gating by the N-Terminal Tail Revealed by Voltage Clamp Fluorometry', in BIOPHYSICAL JOURNAL, CELL PRESS, San Diego, CA, Vol. 102, pp. 328A - 328A, presented at 56th Annual Meeting of the Biophysical-Society, San Diego, CA, 25 February 2012 - 29 February 2012, http://dx.doi.org/10.1016/j.bpj.2011.11.1800

Szekely D; Dokos S; Vandenberg JI; Hill AP, 2010, 'An Improved Curvilinear Gradient Method for Parameter Estimation in Complex Model Systems: Application to Gating of A Cardiac Ion Channel', in BIOPHYSICAL JOURNAL, CELL PRESS, Vol. 98, pp. 140A - 141A, http://dx.doi.org/10.1016/j.bpj.2009.12.758

Mann SA; Hill A; Vandenberg JI, 2009, 'Investigating Ion Channel Diseases With Dynamic Action Potential Clamp', in BIOPHYSICAL JOURNAL, CELL PRESS, Vol. 96, pp. 259A - 259A, http://dx.doi.org/10.1016/j.bpj.2008.12.1279

Hill AP; Varghese A; Dokos S; Mann S; Vandenberg JI, 2009, 'Developing In Silico Descriptions Of Herg Channel Gating', in BIOPHYSICAL JOURNAL, CELL PRESS, pp. 191A - 191A, http://dx.doi.org/10.1016/j.bpj.2008.12.897

Vandenberg JI; Hill AP; Campbell TJ; Clarke CE, 2006, Reply from Jamie I. Vandenberg, Adam P. Hill, Terence J. Campbell, Catherine E. Clarke [2], http://dx.doi.org/10.1113/jphysiol.2006.577102

Ballouz S; Mangala M; Perry M; Heitmann S; Gillis J; Hill A; Vandenberg J, 2019, Co-expression of calcium channels and delayed rectifier potassium channels protects the heart from proarrhythmic events, http://dx.doi.org10.1101/659821

Lee W; Windley MJ; Perry MD; Vandenberg JI; Hill AP, Protocol-dependent differences in IC50 values measured in hERG assays occur in a predictable way and can be used to quantify state preference of drug binding, http://dx.doi.org/10.1101/534867

Pineda S; Nikolova-Krstevski V; Leimena C; Atkinson AJ; Altekoester A-K; Cox CD; Jacoby A; Huttner IG; Ju Y-K; Soka M; Ohanian M; Trivedi G; Kalvakuri S; Johnson R; Molenaar P; Kuchar D; Allen DG; van Helden DF; Harvey RP; Hill AP; Bodmer R; Vogler G; Dobrzynski H; Ocorr K; Fatkin D, Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, KCa1.1, in Sinus Node Function and Arrhythmia Risk, http://dx.doi.org/10.1101/2020.06.28.176495

TeBay C; McArthur J; Mangala M; Kerr N; Heitmann STEWART; Perry M; Windley M; VaAndenberg J; Hill A, Comprehensive preclinical evaluation of how cardiac safety profiles of potential COVID-19 drugs are modified by disease associated factors., http://dx.doi.org/10.22541/au.161429217.72966648/v1

Lei CL; Fabbri A; Whittaker DG; Clerx M; Windley MJ; Hill AP; Mirams GR; de Boer TP, 2021, 'A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer', Wellcome Open Research, vol. 5, pp. 152 - 152, http://dx.doi.org/10.12688/wellcomeopenres.15968.2

Pineda S; Nikolova-Krstevski V; Leimena C; Atkinson AJ; Altekoester AK; Cox CD; Jacoby A; Huttner IG; Ju YK; Soka M; Ohanian M; Trivedi G; Kalvakuri S; Birker K; Johnson R; Molenaar P; Kuchar D; Allen DG; Van Helden DF; Harvey RP; Hill AP; Bodmer R; Vogler G; Dobrzynski H; Ocorr K; Fatkin D, 2021, 'Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, KCa1.1, in Sinus Node Function and Arrhythmia Risk', Circulation: Genomic and Precision Medicine, pp. 230 - 242, http://dx.doi.org/10.1161/CIRCGEN.120.003144

Ballouz S; Mangala MM; Perry MD; Heitmann S; Gillis JA; Hill AP; Vandenberg JI, 2021, 'Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events', Cardiovascular Research, vol. 117, pp. 2216 - 2227, http://dx.doi.org/10.1093/cvr/cvaa280

Ng CA; Farr J; Young P; Windley MJ; Perry MD; Hill AP; Vandenberg JI, 2021, 'Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-Throughput automated patch clamp electrophysiology', Biology Methods and Protocols, vol. 6, pp. bpab003, http://dx.doi.org/10.1093/biomethods/bpab003

Heitmann S; Shpak A; Vandenberg JI; Hill AP, 2021, 'Arrhythmogenic effects of ultra-long and bistable cardiac action potentials', PLoS Computational Biology, vol. 17, http://dx.doi.org/10.1371/JOURNAL.PCBI.1008683

Ross S; Holliday M; Lim S; Mangala M; Perry M; Gray B; Fraser S; Hill A; Hudson J; Semsarian C, 2021, 'Functional Analysis of a Novel Heterozygous Variant in CASQ2 as a Distinct Cause of Catecholaminergic Polymorphic Ventricular Tachycardia', Heart, Lung and Circulation, vol. 30, pp. S96 - S96, http://dx.doi.org/10.1016/j.hlc.2021.06.016

Ng CA; Perry MD; Liang W; Smith NJ; Foo B; Shrier A; Lukacs GL; Hill AP; Vandenberg JI, 2020, 'High-throughput phenotyping of heteromeric human ether-à-go-go-related gene potassium channel variants can discriminate pathogenic from rare benign variants', Heart Rhythm, vol. 17, pp. 492 - 500, http://dx.doi.org/10.1016/j.hrthm.2019.09.020

Perry MD; Ng CA; Mangala MM; Ng TYM; Hines AD; Liang W; Xu MJO; Hill AP; Vandenberg JI, 2020, 'Pharmacological activation of IKrin models of long QT Type 2 risks overcorrection of repolarization', Cardiovascular Research, vol. 116, pp. 1434 - 1445, http://dx.doi.org/10.1093/cvr/cvz247

Li Z; Mirams GR; Yoshinaga T; Ridder BJ; Han X; Chen JE; Stockbridge NL; Wisialowski TA; Damiano B; Severi S; Morissette P; Kowey PR; Holbrook M; Smith G; Rasmusson RL; Liu M; Song Z; Qu Z; Leishman DJ; Steidl-Nichols J; Rodriguez B; Bueno-Orovio A; Zhou X; Passini E; Edwards AG; Morotti S; Ni H; Grandi E; Clancy CE; Vandenberg J; Hill A; Nakamura M; Singer T; Polonchuk L; Greiter-Wilke A; Wang K; Nave S; Fullerton A; Sobie EA; Paci M; Musuamba Tshinanu F; Strauss DG, 2020, 'General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico Strategy', Clinical Pharmacology and Therapeutics, vol. 107, pp. 102 - 111, http://dx.doi.org/10.1002/cpt.1647

Black KA; He S; Jin R; Miller DM; Bolla JR; Clarke OB; Johnson P; Windley M; Burns CJ; Hill AP; Laver D; Robinson CV; Smith BJ; Gulbis JM, 2020, 'A constricted opening in Kir channels does not impede potassium conduction', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-020-16842-0

Lei CL; Fabbri A; Whittaker DG; Clerx M; Windley MJ; Hill AP; Mirams GR; de Boer TP, 2020, 'A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer.', Wellcome Open Res, vol. 5, pp. 152, http://dx.doi.org/10.12688/wellcomeopenres.15968.1

Lee W; Windley MJ; Perry MD; Vandenberg JI; Hill AP, 2019, 'Protocol-dependent differences in IC50 values measured in human ether-á-go-go–related gene assays occur in a predictable way and can be used to quantify state preference of drug binding', Molecular Pharmacology, vol. 95, pp. 537 - 550, http://dx.doi.org/10.1124/mol.118.115220

Hill AP, 2019, 'Introduction to the Australian Society for Biophysics', Biophysical Reviews, vol. 11, pp. 253 - 254, http://dx.doi.org/10.1007/s12551-019-00519-0

Tardo D; Peck M; Hill A; Vandenberg J, 2019, 'T Wave Morphology Biomarkers in Congenital and Acquired Long QT Syndrome', Heart, Lung and Circulation, vol. 28, pp. S229 - S229, http://dx.doi.org/10.1016/j.hlc.2019.06.223

Munawar S; Windley MJ; Tse EG; Todd MH; Hill AP; Vandenberg JI; Jabeen I, 2018, 'Experimentally validated pharmacoinformatics approach to predict hERG inhibition potential of new chemical entities', Frontiers in Pharmacology, vol. 9, http://dx.doi.org/10.3389/fphar.2018.01035

Holliday M; Ross SB; Lim S; Mangala M; Hill A; Szappanos HC; Hool L; Semsarian C, 2018, 'Development of induced pluripotent stem cells from a patient with hypertrophic cardiomyopathy who carries the pathogenic myosin heavy chain 7 mutation p.Arg403Gln', Stem Cell Research, vol. 33, pp. 269 - 273, http://dx.doi.org/10.1016/j.scr.2018.11.011

Beattie KA; Hill AP; Bardenet R; Cui Y; Vandenberg JI; Gavaghan DJ; de Boer TP; Mirams GR, 2018, 'Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics', Journal of Physiology, vol. 596, pp. 1813 - 1828, http://dx.doi.org/10.1113/JP275733

Lee W; Mangala M; Windley M; Perry M; Vandenberg J; Hill A, 2018, 'Novel Pre–Clinical Risk Prediction of Acquired Long QT Syndrome', Heart, Lung and Circulation, vol. 27, pp. S180 - S180, http://dx.doi.org/10.1016/j.hlc.2018.06.309

Windley MJ; Lee W; Vandenberg JI; Hill AP, 2018, 'The temperature dependence of kinetics associated with drug block of hERG channels is compound-specific and an important factor for proarrhythmic risk prediction', Molecular Pharmacology, vol. 94, pp. 760 - 769, http://dx.doi.org/10.1124/mol.117.111534

Nikolova-Krstevski V; Wagner S; Yu ZY; Cox CD; Cvetkovska J; Hill AP; Huttner IG; Benson V; Werdich AA; MacRae C; Feneley MP; Friedrich O; Martinac B; Fatkin D, 2017, 'Endocardial TRPC-6 Channels Act as Atrial Mechanosensors and Load-Dependent Modulators of Endocardial/Myocardial Cross-Talk', JACC: Basic to Translational Science, vol. 2, pp. 575 - 590, http://dx.doi.org/10.1016/j.jacbts.2017.05.006

Bavi N; Martinac AD; Cortes DM; Bavi O; Ridone P; Nomura T; Hill AP; Martinac B; Perozo E, 2017, 'Structural Dynamics of the MscL C-terminal Domain', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/s41598-017-17396-w

Lee W; Windley MJ; Vandenberg JI; Hill AP, 2017, 'In vitro and in silico risk assessment in acquired long QT syndrome: The devil is in the details', Frontiers in Physiology, vol. 8, http://dx.doi.org/10.3389/fphys.2017.00934

Vandenberg JI; Perry MD; Hill AP, 2017, 'Recent advances in understanding and prevention of sudden cardiac death', F1000Research, vol. 6, http://dx.doi.org/10.12688/f1000research.11855.1

Windley MJ; Abi-Gerges N; Fermini B; Hancox JC; Vandenberg JI; Hill AP, 2017, 'Measuring kinetics and potency of hERG block for CiPA', Journal of Pharmacological and Toxicological Methods, vol. 87, pp. 99 - 107, http://dx.doi.org/10.1016/j.vascn.2017.02.017

Bavi N; Bavi O; Vossoughi M; Naghdabadi R; Hill AP; Martinac B; Jamali Y, 2017, 'Nanomechanical properties of MscL α helices: A steered molecular dynamics study', Channels, vol. 11, pp. 209 - 223, http://dx.doi.org/10.1080/19336950.2016.1249077

Hill AP, 2017, 'Boosting the reserves: additive regulation of cardiac repolarisation', Journal of Physiology, vol. 595, pp. 2269 - 2270, http://dx.doi.org/10.1113/JP273940

Mann SA; Imtiaz M; Winbo A; Rydberg A; Perry MD; Couderc JP; Polonsky B; McNitt S; Zareba W; Hill AP; Vandenberg JI, 2016, 'Convergence of models of human ventricular myocyte electrophysiology after global optimization to recapitulate clinical long QT phenotypes', Journal of Molecular and Cellular Cardiology, vol. 100, pp. 25 - 34, http://dx.doi.org/10.1016/j.yjmcc.2016.09.011

Lee W; Mann SA; Windley MJ; Imtiaz MS; Vandenberg JI; Hill AP, 2016, 'In silico assessment of kinetics and state dependent binding properties of drugs causing acquired LQTS', Progress in Biophysics and Molecular Biology, vol. 120, pp. 89 - 99, http://dx.doi.org/10.1016/j.pbiomolbio.2015.12.005

Perry MD; Ng CA; Phan K; David E; Steer K; Hunter MJ; Mann SA; Imtiaz M; Hill AP; Ke Y; Vandenberg JI, 2016, 'Rescue of protein expression defects may not be enough to abolish the pro-arrhythmic phenotype of long QT type 2 mutations', Journal of Physiology, vol. 594, pp. 4031 - 4049, http://dx.doi.org/10.1113/JP271805

Bavi N; Cortes DM; Cox CD; Rohde PR; Liu W; Deitmer JW; Bavi O; Strop P; Hill AP; Rees D; Corry B; Perozo E; Martinac B, 2016, 'The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels', Nature Communications, vol. 7, http://dx.doi.org/10.1038/ncomms11984

Hill AP; Perry MD; Abi-Gerges N; Couderc JP; Fermini B; Hancox JC; Knollmann BC; Mirams GR; Skinner J; Zareba W; Vandenberg JI, 2016, 'Computational cardiology and risk stratification for sudden cardiac death: one of the grand challenges for cardiology in the 21st century', Journal of Physiology, vol. 594, pp. 6893 - 6908, http://dx.doi.org/10.1113/JP272015

Immanuel SA; Sadrieh A; Baumert M; Couderc JP; Zareba W; Hill AP; Vandenberg JI, 2016, 'T-wave morphology can distinguish healthy controls from LQTS patients', Physiological Measurement, vol. 37, pp. 1456 - 1473, http://dx.doi.org/10.1088/0967-3334/37/9/1456

Windley MJ; Mann SA; Vandenberg JI; Hill AP, 2016, 'Temperature effects on kinetics of KV11.1 drug block have important consequences for in silico proarrhythmic risk prediction', Molecular Pharmacology, vol. 90, pp. 1 - 11, http://dx.doi.org/10.1124/mol.115.103127

Hodkinson EC; Neijts M; Sadrieh A; Imtiaz MS; Baumert M; Subbiah RN; Hayward CS; Boomsma D; Willemsen G; Vandenberg JI; Hill AP; De Geus E, 2016, 'Heritability of ECG biomarkers in the Netherlands twin registry measured from Holter ECGs', Frontiers in Physiology, vol. 7, http://dx.doi.org/10.3389/fphys.2016.00154

Immanuel S; Sadrieh A; Baumert M; Couderc J; Zareba W; Hill A; Vandenberg J, 2016, 'T Wave Morphology Can Distinguish Healthy Controls From LQTS Patients With Normal QT Intervals', Heart, Lung and Circulation, vol. 25, pp. S262 - S262, http://dx.doi.org/10.1016/j.hlc.2016.06.610

Chaudhuri R; Sadrieh A; Hoffman NJ; Parker BL; Humphrey SJ; Stöckli J; Hill AP; James DE; Yang JYH, 2015, 'PhosphOrtholog: A web-based tool for cross-species mapping of orthologous protein post-translational modifications', BMC Genomics, vol. 16, http://dx.doi.org/10.1186/s12864-015-1820-x

Perry MD; Ng CA; Mann SA; Sadrieh A; Imtiaz M; Hill AP; Vandenberg JI, 2015, 'Getting to the heart of hERG K⁺ channel gating', Journal of Physiology, vol. 593, pp. 2575 - 2585, http://dx.doi.org/10.1113/JP270095

Sadrieh A; Domanski L; Pitt-Francis J; Mann SA; Hodkinson EC; Ng CA; Perry MD; Taylor JA; Gavaghan D; Subbiah RN; Vandenberg JI; Hill AP, 2014, 'Multiscale cardiac modelling reveals the origins of notched T waves in long QT syndrome type 2', Nature Communications, vol. 5, http://dx.doi.org/10.1038/ncomms6069

Ng CA; Phan K; Hill AP; Vandenberg JI; Perry MD, 2014, 'Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels', Journal of Biological Chemistry, vol. 289, pp. 25822 - 25832, http://dx.doi.org/10.1074/jbc.M114.558379

Hill AP; Perrin MJ; Heide J; Campbell TJ; Mann SA; Vandenberg JI, 2014, 'Kinetics of drug interaction with the Kv11.1 potassium channel', Molecular Pharmacology, vol. 85, pp. 769 - 776, http://dx.doi.org/10.1124/mol.114.091835

Hodkinson EC; Hill AP; Vandenberg JI, 2014, 'The Romano-Ward syndrome--1964-2014: 50 years of progress.', Irish medical journal, vol. 107, pp. 122 - 124

Sadrieh A; Mann SA; Subbiah RN; Domanski L; Taylor JA; Vandenberg JI; Hill AP, 2013, 'Quantifying the origins of population variability in cardiac electrical activity through sensitivity analysis of the electrocardiogram', Journal of Physiology, vol. 591, pp. 4207 - 4222, http://dx.doi.org/10.1113/jphysiol.2013.251710

Ng CA; Ke Y; Perry MD; Tan PS; Hill AP; Vandenberg JI, 2013, 'C-Terminal β9-Strand of the Cyclic Nucleotide-Binding Homology Domain Stabilizes Activated States of Kv11.1 Channels', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0077032

Ke Y; Ng CA; Hunter MJ; Mann SA; Heide J; Hill AP; Vandenberg JI, 2013, 'Trafficking defects in PAS domain mutant Kv11.1 channels: Roles of reduced domain stability and altered domain-domain interactions', Biochemical Journal, vol. 454, pp. 69 - 77, http://dx.doi.org/10.1042/BJ20130328

Mann S; Sadrieh A; Subbiah R; Domanski L; Taylor J; Vandenberg J; Hill A, 2013, 'Epistatic Interactions of Ion Channels Underlie Variability in Cardiac Electrical Activity. In-silico Analysis of the Electrocardiogram', Heart, Lung and Circulation, vol. 22, pp. S95 - S96, http://dx.doi.org/10.1016/j.hlc.2013.05.226

Tan PS; Perry MD; Ng C; Vandenberg JI; Hill A, 2012, 'Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels', Journal of General Physiology, vol. 140, pp. 293 - 306, http://dx.doi.org/10.1085/jgp.201110761

Yu Y; Hill AP; McCormick DA, 2012, 'Warm body temperature facilitates energy efficient cortical action potentials', PLoS Computational Biology, vol. 8, http://dx.doi.org/10.1371/journal.pcbi.1002456

Pan D; Hill AP; Kashou A; Wilson KA; Tan-Wilson A, 2011, 'Electrophoretic transfer protein zymography', Analytical Biochemistry, vol. 411, pp. 277 - 283, http://dx.doi.org/10.1016/j.ab.2011.01.015

Wang DT; Hill A; Mann SA; Tan P; Vandenberg JI, 2010, 'Mapping the sequence of conformational changes underlying selectivity filter gating in the K(v)11.1 potassium channel', Nature Structural and Molecular Biology, vol. 18, pp. 35 - 41, http://dx.doi.org/10.1038/nsmb.1966

Clarke O; Caputo A; Hill A; Vandenberg JI; Smith B; Gulbis J, 2010, 'Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels', Cell, vol. 141, pp. 1018 - 1029, http://dx.doi.org/10.1016/j.cell.2010.05.003

Zhao JT; Hill A; Varghese A; Cooper A; Swan H; Laitinen-Forsblom P; Rees M; Skinner J; Campbell TJ; Vandenberg JI, 2009, 'Not all hERG pore domain mutations have a severe phenotype: G584S has an inactivation gating defect with mild phenotype compared to G572S, which has a dominant negative trafficking defect and a severe phenotype', Journal of Cardiovascular Electrophysiology, vol. 20, pp. 923 - 930, http://dx.doi.org/10.1111/j.1540-8167.2009.01468.x

Perrin MJ; Campbell TJ; Hill AP; Vandenberg JI, 2009, 'Insight into Accurate Testing of Drugs which Cause the Acquired Long-QT Syndrome', Heart, Lung and Circulation, vol. 18, pp. S135 - S135, http://dx.doi.org/10.1016/j.hlc.2009.05.306

Perrin MJ; Subbiah RN; Vandenberg JI; Hill A, 2008, 'Human ether-a-go-go related gene (hERG) K+ channels: Function and dysfunction', Progress in Biophysics and Molecular Biology, vol. 98, pp. 137 - 148, http://dx.doi.org/10.1016/j.pbiomolbio.2008.10.006

Hill A; Sunde M; Campbell TJ; Vandenberg JI, 2007, 'Mechanism of block of the hERG K+ channel by the scorpion toxin CnErg1', Biophysical Journal, vol. 92, pp. 3915 - 3929, http://dx.doi.org/10.1529/biophysj.106.101956

Hill A; Campbell TJ; Bansal PS; Kuchel PW; Vandenberg JI, 2007, 'The S631A mutation causes a mechanistic switch in the block of hERG channels by CnErgl', Biophysical Journal, vol. 93, pp. 32 - 34, http://dx.doi.org/10.1529/biophysj.107.114561

Hill A; Sunde M; Vandenberg JI, 2007, 'Mechanisms of block of the hERG K+ channel by the scorpion toxin CnErg1', Biophysical Journal, pp. 124A - 124A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000243972400570&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Clarke CE; Hill A; Kondo M; Subbiah RN; Campbell TJ; Vandenberg JI, 2006, 'Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels', The Journal of Physiology, vol. 573, pp. 291 - 304, http://dx.doi.org/10.1113/jphysiol.2006.108332

Hill AP; Kingston O; Sitsapesan R, 2004, 'Functional regulation of the cardiac ryanodine receptor by suramin and calmodulin involves multiple binding sites', Molecular Pharmacology, vol. 65, pp. 1258 - 1268, http://dx.doi.org/10.1124/mol.65.5.1258

Hill AP; Sitsapesan R, 2002, 'DIDS modifies the conductance, gating, and inactivation mechanisms of the cardiac ryanodine receptor', Biophysical Journal, vol. 82, pp. 3037 - 3047, http://dx.doi.org/10.1016/S0006-3495(02)75644-0

Carriero D; Aberman J; Lin SY; Hill A; Makriyannis A; Salamone JD, 1998, 'A detailed characterization of the effects of four cannabinoid agonists on operant lever pressing', Psychopharmacology, vol. 137, pp. 147 - 156, http://dx.doi.org/10.1007/s002130050604

Pertwee R; Griffin G; Fernando S; Li X; Hill A; Makriyannis A, 1995, 'AM630, a competitive cannabinoid receptor antagonist', Life Sciences, vol. 56, pp. 1949 - 1955, http://dx.doi.org/10.1016/0024-3205(95)00175-6

Ng C-A; Ullah R; Farr J; Hill AP; Kozek KA; Vanags LR; Mitchell D; Kroncke BM; Vandenberg JI, 'A Massively Parallel Trafficking Assay Accurately Predicts Loss of Channel Function in KCNH2 Variants', , http://dx.doi.org/10.1101/2021.07.10.451881

Heitmann S; Vandenberg JI; Hill AP, 'Arrhythmogenesis as the failure of repolarization', , http://dx.doi.org/10.1101/2020.07.02.185694

Ng C-A; Farr J; Young P; Windley MJ; Perry MD; Hill AP; Vandenberg JI, 'Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology', , http://dx.doi.org/10.1101/2021.02.02.427891

TeBay C; McArthur JR; Mangala M; Kerr N; Heitmann S; Perry MD; Windley MJ; Vandenberg JI; Hill AP, 2021, 'Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation.', Br J Pharmacol, http://dx.doi.org/10.1111/bph.15757