Conjoint Senior Lecturer

Dr Bruce Duncan Walker

medicine-health
St Vincent's Clinical School
Phone
2 93391111

Publications

  • Book Chapters | 2018
    Dr Bruce Duncan Walker
    Ranasinghe S; Walker B, 2018, 'HIV and SIV, CD8 T Cell Responses to', in Encyclopedia of AIDS, Springer New York, pp. 669 - 677, http://dx.doi.org/10.1007/978-1-4939-7101-5_185
    Book Chapters | 2016
    Dr Bruce Duncan Walker
    Walker BD, 2016, 'AIDS Vaccines', in The Vaccine Book, Elsevier, pp. 401 - 422, http://dx.doi.org/10.1016/b978-0-12-802174-3.00020-5
    Book Chapters | 2015
    Dr Bruce Duncan Walker
    Ranasinghe S; Walker B, 2015, 'HIV and SIV, CD8 T Cell Responses to', in Encyclopedia of AIDS, Springer New York, pp. 1 - 9, http://dx.doi.org/10.1007/978-1-4614-9610-6_185-1
    Book Chapters | 2014
    Dr Bruce Duncan Walker
    Wong DKH; Walker BD, 2014, 'Hepatitis C Virus', in Human Tumor Viruses, ASM Press, pp. 301 - 329, http://dx.doi.org/10.1128/9781555818289.ch10
    Book Chapters | 2012
    Dr Bruce Duncan Walker
    Gray CM; Gumbi P; Zembe L; Radebe M; Walker B, 2012, 'The immune response to HIV', in Sande's HIV/AIDS Medicine, Elsevier, pp. 45 - 57, http://dx.doi.org/10.1016/b978-1-4557-0695-2.00004-3
    Book Chapters | 2012
    Dr Bruce Duncan Walker
    Pereyra F; Walker BD, 2012, 'Immune Responses Associated to Viral Control', in Models of Protection Against HIV/SIV, Elsevier, pp. 273 - 291, http://dx.doi.org/10.1016/b978-0-12-387715-4.00010-1
    Book Chapters | 2008
    Dr Bruce Duncan Walker
    Gray CM; Walker B, 2008, 'The Immune Response to HIV', in Global HIV/AIDS Medicine, Elsevier, pp. 39 - 49, http://dx.doi.org/10.1016/b978-1-4160-2882-6.50008-3
    Book Chapters | 2005
    Dr Bruce Duncan Walker
    Skanes AC; Walker B; Lelorier P; Klein GJ, 2005, 'Asymptomatic ECG Abnormalities', in Electrophysiological Disorders of the Heart, pp. 479 - 490, http://dx.doi.org/10.1016/B978-0-443-06570-5.50028-9
    Book Chapters | 2004
    Dr Bruce Duncan Walker
    Yu XG; Altfeld M; Walker BD, 2004, 'Human Genetics and HIV-1 Infection', in AIDS in Asia, Springer US, pp. 207 - 221, http://dx.doi.org/10.1007/978-0-306-48536-7_17
    Book Chapters | 2001
    Dr Bruce Duncan Walker
    Boggiano C; Pinilla C; Walker BD; Blondelle SE, 2001, 'Identification and Optimization of HIV-Specific CTL Antigens for Vaccine Design', in Peptides: The Wave of the Future, Springer Netherlands, pp. 1023 - 1024, http://dx.doi.org/10.1007/978-94-010-0464-0_478
    Book Chapters | 1998
    Dr Bruce Duncan Walker
    Walker BD; Rosenberg ES; Hay CM; Basgoz N; Yang OO, 1998, 'Immune control of HIV-1 replication.', in , pp. 159 - 167, http://dx.doi.org/10.1007/978-1-4615-5355-7_17
    Book Chapters | 1997
    Dr Bruce Duncan Walker
    Jassoy C; Walker BD, 1997, 'HIV-1-specific cytotoxic T lymphocytes and the control of HIV-1 replication', in Immunopathogenesis of HIV Infection, Springer Berlin Heidelberg, pp. 89 - 102, http://dx.doi.org/10.1007/978-3-642-60867-4_7
    Book Chapters | 1997
    Dr Bruce Duncan Walker
    Yang OO; Walker BD, 1997, 'CD8+ cells in human immunodeficiency virus type I pathogenesis: cytolytic and noncytolytic inhibition of viral replication.', in , pp. 273 - 311, http://dx.doi.org/10.1016/s0065-2776(08)60600-8
    Book Chapters | 1995
    Dr Bruce Duncan Walker
    Kalams SA; Walker BD, 1995, 'Cytotoxic T lymphocytes and HIV-1 related neurologic disorders.', in , pp. 79 - 88, http://dx.doi.org/10.1007/978-3-642-79657-9_6
    Book Chapters | 1994
    Dr Bruce Duncan Walker
    Houghton M; Choo Q-L; Kuo G; Ralston R; Selby M; Weiner A; Chien D; Han J; Walker C; Abrignani S; Koziel M; Walker B; Cummins L; Muchmore E, 1994, 'The Hepatitis C Virus: Genetic Organization, Persistence, and Vaccine Strategies', in Viral Hepatitis and Liver Disease, Springer Japan, pp. 33 - 37, http://dx.doi.org/10.1007/978-4-431-68255-4_9
    Book Chapters | 1994
    Dr Bruce Duncan Walker
    Johnson RP; Walker BD, 1994, 'Cytotoxic T lymphocytes in human immunodeficiency virus infection: responses to structural proteins.', in , pp. 35 - 63, http://dx.doi.org/10.1007/978-3-642-78530-6_3
    Book Chapters | 1990
    Dr Bruce Duncan Walker
    Johnson VA; Byington RE; Walker BD; Kaplan JC; Potts BJ; Koup RA; Ho DD; Go AS; Zack JA; Arrigo SJ; Chen ISY, 1990, 'Quantitative Assays for Virus Detection', in Techniques in HIV Research, Palgrave Macmillan UK, pp. 87 - 119, http://dx.doi.org/10.1007/978-1-349-11888-5_5
    Book Chapters |
    Dr Bruce Duncan Walker
    Julg B; Walker BD, 'HIV Immunology and Prospects for Vaccines', in AIDS and Tuberculosis, Wiley-VCH Verlag GmbH & Co. KGaA, pp. 1 - 29, http://dx.doi.org/10.1002/9783527627905.ch1
  • Journal articles | 2021
    Dr Bruce Duncan Walker
    Garcia-Bates TM; Palma ML; Anderko RR; Hsu DC; Ananworanich J; Korber BT; Gaiha GD; Phanuphak N; Thomas R; Tovanabutra S; Walker BD; Mellors JW; Piazza PA; Kroon E; Riddler SA; Michael NL; Rinaldo CR; Mailliard RB; I4C and RV254 Study Groups , 2021, 'Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes.', EBioMedicine, vol. 63, pp. 103175, http://dx.doi.org/10.1016/j.ebiom.2020.103175
    Journal articles | 2021
    Dr Bruce Duncan Walker
    McCann CD; van Dorp CH; Danesh A; Ward AR; Dilling TR; Mota TM; Zale E; Stevenson EM; Patel S; Brumme CJ; Dong W; Jones DS; Andresen TL; Walker BD; Brumme ZL; Bollard CM; Perelson AS; Irvine DJ; Jones RB, 2021, 'A participant-derived xenograft model of HIV enables long-term evaluation of autologous immunotherapies.', J Exp Med, vol. 218, http://dx.doi.org/10.1084/jem.20201908
    Journal articles | 2021
    Dr Bruce Duncan Walker
    Clayton KL; Mylvaganam G; Villasmil-Ocando A; Stuart H; Maus MV; Rashidian M; Ploegh HL; Walker BD, 2021, 'HIV-infected macrophages resist efficient NK cell-mediated killing while preserving inflammatory cytokine responses.', Cell Host Microbe, vol. 29, pp. 435 - 447.e9, http://dx.doi.org/10.1016/j.chom.2021.01.006
    Journal articles | 2021
    Dr Bruce Duncan Walker
    Singh R; Ramsuran V; Naranbhai V; Yende-Zuma N; Garrett N; Mlisana K; Dong KL; Walker BD; Abdool Karim SS; Carrington M; Ndung'u T, 2021, 'Epigenetic Regulation of BST-2 Expression Levels and the Effect on HIV-1 Pathogenesis.', Front Immunol, vol. 12, pp. 669241, http://dx.doi.org/10.3389/fimmu.2021.669241
    Journal articles | 2020
    Dr Bruce Duncan Walker
    Jiang C; Lian X; Gao C; Sun X; Einkauf KB; Chevalier JM; Chen SMY; Hua S; Rhee B; Chang K; Blackmer JE; Osborn M; Peluso MJ; Hoh R; Somsouk M; Milush J; Bertagnolli LN; Sweet SE; Varriale JA; Burbelo PD; Chun T-W; Laird GM; Serrao E; Engelman AN; Carrington M; Siliciano RF; Siliciano JM; Deeks SG; Walker BD; Lichterfeld M; Yu XG, 2020, 'Distinct viral reservoirs in individuals with spontaneous control of HIV-1.', Nature, vol. 585, pp. 261 - 267, http://dx.doi.org/10.1038/s41586-020-2651-8
    Journal articles | 2020
    Dr Bruce Duncan Walker
    Collins DR; Gaiha GD; Walker BD, 2020, 'CD8+ T cells in HIV control, cure and prevention.', Nat Rev Immunol, vol. 20, pp. 471 - 482, http://dx.doi.org/10.1038/s41577-020-0274-9
    Journal articles | 2020
    Dr Bruce Duncan Walker
    Choi B; Choudhary MC; Regan J; Sparks JA; Padera RF; Qiu X; Solomon IH; Kuo H-H; Boucau J; Bowman K; Adhikari UD; Winkler ML; Mueller AA; Hsu TY-T; Desjardins M; Baden LR; Chan BT; Walker BD; Lichterfeld M; Brigl M; Kwon DS; Kanjilal S; Richardson ET; Jonsson AH; Alter G; Barczak AK; Hanage WP; Yu XG; Gaiha GD; Seaman MS; Cernadas M; Li JZ, 2020, 'Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host.', N Engl J Med, vol. 383, pp. 2291 - 2293, http://dx.doi.org/10.1056/NEJMc2031364
    Journal articles | 2020
    Dr Bruce Duncan Walker
    Fajnzylber J; Regan J; Coxen K; Corry H; Wong C; Rosenthal A; Worrall D; Giguel F; Piechocka-Trocha A; Atyeo C; Fischinger S; Chan A; Flaherty KT; Hall K; Dougan M; Ryan ET; Gillespie E; Chishti R; Li Y; Jilg N; Hanidziar D; Baron RM; Baden L; Tsibris AM; Armstrong KA; Kuritzkes DR; Alter G; Walker BD; Yu X; Li JZ; Massachusetts Consortium for Pathogen Readiness , 2020, 'SARS-CoV-2 viral load is associated with increased disease severity and mortality.', Nat Commun, vol. 11, pp. 5493, http://dx.doi.org/10.1038/s41467-020-19057-5
    Journal articles | 2020
    Dr Bruce Duncan Walker
    Joung J; Ladha A; Saito M; Kim N-G; Woolley AE; Segel M; Barretto RPJ; Ranu A; Macrae RK; Faure G; Ioannidi EI; Krajeski RN; Bruneau R; Huang M-LW; Yu XG; Li JZ; Walker BD; Hung DT; Greninger AL; Jerome KR; Gootenberg JS; Abudayyeh OO; Zhang F, 2020, 'Detection of SARS-CoV-2 with SHERLOCK One-Pot Testing.', N Engl J Med, vol. 383, pp. 1492 - 1494, http://dx.doi.org/10.1056/NEJMc2026172
    Journal articles | 2020
    Dr Bruce Duncan Walker
    Kaneko N; Kuo H-H; Boucau J; Farmer JR; Allard-Chamard H; Mahajan VS; Piechocka-Trocha A; Lefteri K; Osborn M; Bals J; Bartsch YC; Bonheur N; Caradonna TM; Chevalier J; Chowdhury F; Diefenbach TJ; Einkauf K; Fallon J; Feldman J; Finn KK; Garcia-Broncano P; Hartana CA; Hauser BM; Jiang C; Kaplonek P; Karpell M; Koscher EC; Lian X; Liu H; Liu J; Ly NL; Michell AR; Rassadkina Y; Seiger K; Sessa L; Shin S; Singh N; Sun W; Sun X; Ticheli HJ; Waring MT; Zhu AL; Alter G; Li JZ; Lingwood D; Schmidt AG; Lichterfeld M; Walker BD; Yu XG; Padera RF; Pillai S; Massachusetts Consortium on Pathogen Readiness Specimen Working Group , 2020, 'Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19.', Cell, vol. 183, pp. 143 - 157.e13, http://dx.doi.org/10.1016/j.cell.2020.08.025
    Journal articles | 2020
    Dr Bruce Duncan Walker
    Painter MM; Zimmerman GE; Merlino MS; Robertson AW; Terry VH; Ren X; McLeod MR; Gomez-Rodriguez L; Garcia KA; Leonard JA; Leopold KE; Neevel AJ; Lubow J; Olson E; Piechocka-Trocha A; Collins DR; Tripathi A; Raghavan M; Walker BD; Hurley JH; Sherman DH; Collins KL, 2020, 'Concanamycin A counteracts HIV-1 Nef to enhance immune clearance of infected primary cells by cytotoxic T lymphocytes.', Proc Natl Acad Sci U S A, vol. 117, pp. 23835 - 23846, http://dx.doi.org/10.1073/pnas.2008615117
    Journal articles | 2020
    Dr Bruce Duncan Walker
    Millar JR; Bengu N; Fillis R; Sprenger K; Ntlantsana V; Vieira VA; Khambati N; Archary M; Muenchhoff M; Groll A; Grayson N; Adamson J; Govender K; Dong K; Kiepiela P; Walker BD; Bonsall D; Connor T; Bull MJ; Nxele N; Roider J; Ismail N; Adland E; Puertas MC; Martinez-Picado J; Matthews PC; Ndung'u T; Goulder P; Ucwaningo Lwabantwana Consortium , 2020, 'HIGH-FREQUENCY failure of combination antiretroviral therapy in paediatric HIV infection is associated with unmet maternal needs causing maternal NON-ADHERENCE.', EClinicalMedicine, vol. 22, pp. 100344, http://dx.doi.org/10.1016/j.eclinm.2020.100344
    Journal articles | 2020
    Dr Bruce Duncan Walker
    Shrock E; Fujimura E; Kula T; Timms RT; Lee I-H; Leng Y; Robinson ML; Sie BM; Li MZ; Chen Y; Logue J; Zuiani A; McCulloch D; Lelis FJN; Henson S; Monaco DR; Travers M; Habibi S; Clarke WA; Caturegli P; Laeyendecker O; Piechocka-Trocha A; Li JZ; Khatri A; Chu HY; MGH COVID-19 Collection & Processing Team ; Villani A-C; Kays K; Goldberg MB; Hacohen N; Filbin MR; Yu XG; Walker BD; Wesemann DR; Larman HB; Lederer JA; Elledge SJ, 2020, 'Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity.', Science, vol. 370, http://dx.doi.org/10.1126/science.abd4250
    Journal articles | 2020
    Dr Bruce Duncan Walker
    Kazer SW; Aicher TP; Muema DM; Carroll SL; Ordovas-Montanes J; Miao VN; Tu AA; Ziegler CGK; Nyquist SK; Wong EB; Ismail N; Dong M; Moodley A; Berger B; Love JC; Dong KL; Leslie A; Ndhlovu ZM; Ndung'u T; Walker BD; Shalek AK, 2020, 'Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection.', Nat Med, vol. 26, pp. 511 - 518, http://dx.doi.org/10.1038/s41591-020-0799-2
    Journal articles | 2020
    Dr Bruce Duncan Walker
    Martin-Gayo E; Gao C; Chen HR; Ouyang Z; Kim D; Kolb KE; Shalek AK; Walker BD; Lichterfeld M; Yu XG, 2020, 'Immunological Fingerprints of Controllers Developing Neutralizing HIV-1 Antibodies.', Cell Rep, vol. 30, pp. 984 - 996.e4, http://dx.doi.org/10.1016/j.celrep.2019.12.087
    Journal articles | 2020
    Dr Bruce Duncan Walker
    Ndlovu B; Gounder K; Muema D; Raju N; Hermanus T; Mthethwa Q; Robertson K; Walker BD; Georgiev IS; Morris L; Moore PL; Ndung'u T, 2020, 'Envelope characteristics in individuals who developed neutralizing antibodies targeting different epitopes in HIV-1 subtype C infection.', Virology, vol. 546, pp. 1 - 12, http://dx.doi.org/10.1016/j.virol.2020.03.003
    Journal articles | 2020
    Dr Bruce Duncan Walker
    Muema DM; Akilimali NA; Ndumnego OC; Rasehlo SS; Durgiah R; Ojwach DBA; Ismail N; Dong M; Moodley A; Dong KL; Ndhlovu ZM; Mabuka JM; Walker BD; Mann JK; Ndung'u T, 2020, 'Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection.', BMC Med, vol. 18, pp. 81, http://dx.doi.org/10.1186/s12916-020-01529-6
    Journal articles | 2020
    Dr Bruce Duncan Walker
    Kazer SW; Walker BD; Shalek AK, 2020, 'Evolution and Diversity of Immune Responses during Acute HIV Infection.', Immunity, vol. 53, pp. 908 - 924, http://dx.doi.org/10.1016/j.immuni.2020.10.015
    Journal articles | 2019
    Dr Bruce Duncan Walker
    Jin SW; Alsahafi N; Kuang XT; Swann SA; Toyoda M; Göttlinger H; Walker BD; Ueno T; Finzi A; Brumme ZL; Brockman MA, 2019, 'Natural HIV-1 Nef Polymorphisms Impair SERINC5 Downregulation Activity.', Cell Rep, vol. 29, pp. 1449 - 1457.e5, http://dx.doi.org/10.1016/j.celrep.2019.10.007
    Journal articles | 2019
    Dr Bruce Duncan Walker
    Mori M; Leitman E; Walker B; Ndung'u T; Carrington M; Goulder P, 2019, 'Impact of HLA Allele-KIR Pairs on HIV Clinical Outcome in South Africa.', J Infect Dis, vol. 219, pp. 1456 - 1463, http://dx.doi.org/10.1093/infdis/jiy692
    Journal articles | 2019
    Dr Bruce Duncan Walker
    Monel B; McKeon A; Lamothe-Molina P; Jani P; Boucau J; Pacheco Y; Jones RB; Le Gall S; Walker BD, 2019, 'HIV Controllers Exhibit Effective CD8+ T Cell Recognition of HIV-1-Infected Non-activated CD4+ T Cells.', Cell Rep, vol. 27, pp. 142 - 153.e4, http://dx.doi.org/10.1016/j.celrep.2019.03.016
    Journal articles | 2019
    Dr Bruce Duncan Walker
    Mylvaganam G; Yanez AG; Maus M; Walker BD, 2019, 'Toward T Cell-Mediated Control or Elimination of HIV Reservoirs: Lessons From Cancer Immunology.', Front Immunol, vol. 10, pp. 2109, http://dx.doi.org/10.3389/fimmu.2019.02109
    Journal articles | 2019
    Dr Bruce Duncan Walker
    Ndhlovu ZM; Kazer SW; Nkosi T; Ogunshola F; Muema DM; Anmole G; Swann SA; Moodley A; Dong K; Reddy T; Brockman MA; Shalek AK; Ndung'u T; Walker BD, 2019, 'Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection.', Sci Transl Med, vol. 11, http://dx.doi.org/10.1126/scitranslmed.aau0528
    Journal articles | 2019
    Dr Bruce Duncan Walker
    Gaiha GD; Rossin EJ; Urbach J; Landeros C; Collins DR; Nwonu C; Muzhingi I; Anahtar MN; Waring OM; Piechocka-Trocha A; Waring M; Worrall DP; Ghebremichael MS; Newman RM; Power KA; Allen TM; Chodosh J; Walker BD, 2019, 'Structural topology defines protective CD8+ T cell epitopes in the HIV proteome.', Science, vol. 364, pp. 480 - 484, http://dx.doi.org/10.1126/science.aav5095
    Journal articles | 2019
    Dr Bruce Duncan Walker
    Gonzalo-Gil E; Rapuano PB; Ikediobi U; Leibowitz R; Mehta S; Coskun AK; Porterfield JZ; Lampkin TD; Marconi VC; Rimland D; Walker BD; Deeks S; Sutton RE, 2019, 'Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and their family members.', Elife, vol. 8, http://dx.doi.org/10.7554/eLife.44360
    Journal articles | 2019
    Dr Bruce Duncan Walker
    Lee GQ; Reddy K; Einkauf KB; Gounder K; Chevalier JM; Dong KL; Walker BD; Yu XG; Ndung'u T; Lichterfeld M, 2019, 'HIV-1 DNA sequence diversity and evolution during acute subtype C infection.', Nat Commun, vol. 10, pp. 2737, http://dx.doi.org/10.1038/s41467-019-10659-2
    Journal articles | 2019
    Dr Bruce Duncan Walker
    Kulkarni S; Lied A; Kulkarni V; Rucevic M; Martin MP; Walker-Sperling V; Anderson SK; Ewy R; Singh S; Nguyen H; McLaren PJ; Viard M; Naranbhai V; Zou C; Lin Z; Gatanaga H; Oka S; Takiguchi M; Thio CL; Margolick J; Kirk GD; Goedert JJ; Hoots WK; Deeks SG; Haas DW; Michael N; Walker B; Le Gall S; Chowdhury FZ; Yu XG; Carrington M, 2019, 'CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome.', Nat Immunol, vol. 20, pp. 824 - 834, http://dx.doi.org/10.1038/s41590-019-0406-1
    Journal articles | 2019
    Dr Bruce Duncan Walker
    Kulkarni S; Lied A; Kulkarni V; Rucevic M; Martin MP; Walker-Sperling V; Anderson SK; Ewy R; Singh S; Nguyen H; McLaren PJ; Viard M; Naranbhai V; Zou C; Lin Z; Gatanaga H; Oka S; Takiguchi M; Thio CL; Margolick J; Kirk GD; Goedert JJ; Hoots WK; Deeks SG; Haas DW; Michael N; Walker B; Le Gall S; Chowdhury FZ; Yu XG; Carrington M, 2019, 'Author Correction: CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome.', Nat Immunol, vol. 20, pp. 1555, http://dx.doi.org/10.1038/s41590-019-0516-9
    Journal articles | 2019
    Dr Bruce Duncan Walker
    Clayton K; Stuart H; Mylvaganam G; Villasmil Ocando A; Maus M; Walker B, 2019, 'HIV-infected macrophages evade NK cell-mediated killing while driving inflammation', Journal of Virus Eradication, vol. 5, pp. 35 - 35, http://dx.doi.org/10.1016/s2055-6640(20)30166-7
    Journal articles | 2019
    Dr Bruce Duncan Walker
    Baiyegunhi O; Mann J; Nkosi T; Pansegrou J; Dong K; Ndungu T; Walker B; Ndhlovu Z, 2019, 'High HIV viral burden persists in CXCR3+TFH despite very early cART initiation', Journal of Virus Eradication, vol. 5, pp. 19 - 19, http://dx.doi.org/10.1016/s2055-6640(20)31059-1
    Journal articles | 2019
    Dr Bruce Duncan Walker
    Phan J; Kerr N; Walker B; Subbiah R, 2019, 'Cardiac Magnetic Resonance Imaging and Position Emission Tomography in the Evaluation of Patients with Suspected Cardiac Sarcoidosis: A Single Centre Experience', Heart, Lung and Circulation, vol. 28, pp. S163 - S163, http://dx.doi.org/10.1016/j.hlc.2019.06.070
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Joglekar AV; Liu Z; Weber JK; Ouyang Y; Jeppson JD; Noh WJ; Lamothe-Molina PA; Chen H; Kang S-G; Bethune MT; Zhou R; Walker BD; Baltimore D, 2018, 'T cell receptors for the HIV KK10 epitope from patients with differential immunologic control are functionally indistinguishable.', Proc Natl Acad Sci U S A, vol. 115, pp. 1877 - 1882, http://dx.doi.org/10.1073/pnas.1718659115
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Chowdhury FZ; Ouyang Z; Buzon M; Walker BD; Lichterfeld M; Yu XG, 2018, 'Metabolic pathway activation distinguishes transcriptional signatures of CD8+ T cells from HIV-1 elite controllers.', AIDS, vol. 32, pp. 2669 - 2677, http://dx.doi.org/10.1097/QAD.0000000000002007
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Adland E; Hill M; Lavandier N; Csala A; Edwards A; Chen F; Radkowski M; Kowalska JD; Paraskevis D; Hatzakis A; Valenzuela-Ponce H; Pfafferott K; Williams I; Pellegrino P; Borrow P; Mori M; Rockstroh J; Prado JG; Mothe B; Dalmau J; Martinez-Picado J; Tudor-Williams G; Frater J; Stryhn A; Buus S; Teran GR; Mallal S; John M; Buchbinder S; Kirk G; Martin J; Michael N; Fellay J; Deeks S; Walker B; Avila-Rios S; Cole D; Brander C; Carrington M; Goulder P, 2018, 'Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection.', J Virol, vol. 92, http://dx.doi.org/10.1128/JVI.01685-17
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Ramsuran V; Naranbhai V; Horowitz A; Qi Y; Martin MP; Yuki Y; Gao X; Walker-Sperling V; Del Prete GQ; Schneider DK; Lifson JD; Fellay J; Deeks SG; Martin JN; Goedert JJ; Wolinsky SM; Michael NL; Kirk GD; Buchbinder S; Haas D; Ndung'u T; Goulder P; Parham P; Walker BD; Carlson JM; Carrington M, 2018, 'Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells.', Science, vol. 359, pp. 86 - 90, http://dx.doi.org/10.1126/science.aam8825
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Leipold MD; Obermoser G; Fenwick C; Kleinstuber K; Rashidi N; McNevin JP; Nau AN; Wagar LE; Rozot V; Davis MM; DeRosa S; Pantaleo G; Scriba TJ; Walker BD; Olsen LR; Maecker HT, 2018, 'Comparison of CyTOF assays across sites: Results of a six-center pilot study.', J Immunol Methods, vol. 453, pp. 37 - 43, http://dx.doi.org/10.1016/j.jim.2017.11.008
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Huang S-H; Ren Y; Thomas AS; Chan D; Mueller S; Ward AR; Patel S; Bollard CM; Cruz CR; Karandish S; Truong R; Macedo AB; Bosque A; Kovacs C; Benko E; Piechocka-Trocha A; Wong H; Jeng E; Nixon DF; Ho Y-C; Siliciano RF; Walker BD; Jones RB, 2018, 'Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells.', J Clin Invest, vol. 128, pp. 876 - 889, http://dx.doi.org/10.1172/JCI97555
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Chung AW; Mabuka JM; Ndlovu B; Licht A; Robinson H; Ramlakhan Y; Ghebremichael M; Reddy T; Goulder PJR; Walker BD; Ndung'u T; Alter G, 2018, 'Viral control in chronic HIV-1 subtype C infection is associated with enrichment of p24 IgG1 with Fc effector activity.', AIDS, vol. 32, pp. 1207 - 1217, http://dx.doi.org/10.1097/QAD.0000000000001812
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Siciliano V; DiAndreth B; Monel B; Beal J; Huh J; Clayton KL; Wroblewska L; McKeon A; Walker BD; Weiss R, 2018, 'Engineering modular intracellular protein sensor-actuator devices.', Nat Commun, vol. 9, pp. 1881, http://dx.doi.org/10.1038/s41467-018-03984-5
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Alter G; Dowell KG; Brown EP; Suscovich TJ; Mikhailova A; Mahan AE; Walker BD; Nimmerjahn F; Bailey-Kellogg C; Ackerman ME, 2018, 'High-resolution definition of humoral immune response correlates of effective immunity against HIV.', Mol Syst Biol, vol. 14, pp. e7881, http://dx.doi.org/10.15252/msb.20177881
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Clayton KL; Collins DR; Lengieza J; Ghebremichael M; Dotiwala F; Lieberman J; Walker BD, 2018, 'Resistance of HIV-infected macrophages to CD8+ T lymphocyte-mediated killing drives activation of the immune system.', Nat Immunol, vol. 19, pp. 475 - 486, http://dx.doi.org/10.1038/s41590-018-0085-3
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Namazi G; Fajnzylber JM; Aga E; Bosch RJ; Acosta EP; Sharaf R; Hartogensis W; Jacobson JM; Connick E; Volberding P; Skiest D; Margolis D; Sneller MC; Little SJ; Gianella S; Smith DM; Kuritzkes DR; Gulick RM; Mellors JW; Mehraj V; Gandhi RT; Mitsuyasu R; Schooley RT; Henry K; Tebas P; Deeks SG; Chun T-W; Collier AC; Routy J-P; Hecht FM; Walker BD; Li JZ, 2018, 'The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies.', J Infect Dis, vol. 218, pp. 1954 - 1963, http://dx.doi.org/10.1093/infdis/jiy479
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Ndung'u T; Dong KL; Kwon DS; Walker BD, 2018, 'A FRESH approach: Combining basic science and social good.', Sci Immunol, vol. 3, http://dx.doi.org/10.1126/sciimmunol.aau2798
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Lofano G; Gorman MJ; Yousif AS; Yu W-H; Fox JM; Dugast A-S; Ackerman ME; Suscovich TJ; Weiner J; Barouch D; Streeck H; Little S; Smith D; Richman D; Lauffenburger D; Walker BD; Diamond MS; Alter G, 2018, 'Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement.', Sci Immunol, vol. 3, http://dx.doi.org/10.1126/sciimmunol.aat7796
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Baiyegunhi O; Ndlovu B; Ogunshola F; Ismail N; Walker BD; Ndung'u T; Ndhlovu ZM, 2018, 'Frequencies of Circulating Th1-Biased T Follicular Helper Cells in Acute HIV-1 Infection Correlate with the Development of HIV-Specific Antibody Responses and Lower Set Point Viral Load.', J Virol, vol. 92, http://dx.doi.org/10.1128/JVI.00659-18
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Dong KL; Moodley A; Kwon DS; Ghebremichael MS; Dong M; Ismail N; Ndhlovu ZM; Mabuka JM; Muema DM; Pretorius K; Lin N; Walker BD; Ndung'u T, 2018, 'Detection and treatment of Fiebig stage I HIV-1 infection in young at-risk women in South Africa: a prospective cohort study.', Lancet HIV, vol. 5, pp. e35 - e44, http://dx.doi.org/10.1016/S2352-3018(17)30146-7
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Martin MP; Naranbhai V; Shea PR; Qi Y; Ramsuran V; Vince N; Gao X; Thomas R; Brumme ZL; Carlson JM; Wolinsky SM; Goedert JJ; Walker BD; Segal FP; Deeks SG; Haas DW; Migueles SA; Connors M; Michael N; Fellay J; Gostick E; Llewellyn-Lacey S; Price DA; Lafont BA; Pymm P; Saunders PM; Widjaja J; Wong SC; Vivian JP; Rossjohn J; Brooks AG; Carrington M, 2018, 'Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1.', J Clin Invest, vol. 128, pp. 1903 - 1912, http://dx.doi.org/10.1172/JCI98463
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Cheng HD; Grimm SK; Gilman MS; Gwom LC; Sok D; Sundling C; Donofrio G; Karlsson Hedestam GB; Bonsignori M; Haynes BF; Lahey TP; Maro I; von Reyn CF; Gorny MK; Zolla-Pazner S; Walker BD; Alter G; Burton DR; Robb ML; Krebs SJ; Seaman MS; Bailey-Kellogg C; Ackerman ME, 2018, 'Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site.', JCI Insight, vol. 3, http://dx.doi.org/10.1172/jci.insight.97018
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Martin-Gayo E; Cole MB; Kolb KE; Ouyang Z; Cronin J; Kazer SW; Ordovas-Montanes J; Lichterfeld M; Walker BD; Yosef N; Shalek AK; Yu XG, 2018, 'A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers.', Genome Biol, vol. 19, pp. 10, http://dx.doi.org/10.1186/s13059-017-1385-x
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Walker-Sperling V; Ramsuran V; Martin M; Naranbhai V; Li H; Anderson SK; Rowland-Jones S; Yindom L-M; Ghebremichael M; Ndung’u T; Walker BD; Carrington M, 2018, 'P069UTR SNPS rs111686073 and rs73410010 independently modify expression of tapasin in blacks', Human Immunology, vol. 79, pp. 113 - 113, http://dx.doi.org/10.1016/j.humimm.2018.07.128
    Journal articles | 2018
    Dr Bruce Duncan Walker
    Gounder K; Naidoo V; Padayachi N; Mthethwa Q; Dilernia D; Hunter E; Walker B; Ndung’u T, 2018, 'A20 Deep sequencing reveals viral evolution in GAG within protective HLA Alleles B*57: 02, B*58: 01, and B*7 supertype individuals acutely infected with HIV-1 subtype C in Durban, South Africa', Virus Evolution, vol. 4, http://dx.doi.org/10.1093/ve/vey010.019
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Freund NT; Wang H; Scharf L; Nogueira L; Horwitz JA; Bar-On Y; Golijanin J; Sievers SA; Sok D; Cai H; Cesar Lorenzi JC; Halper-Stromberg A; Toth I; Piechocka-Trocha A; Gristick HB; van Gils MJ; Sanders RW; Wang L-X; Seaman MS; Burton DR; Gazumyan A; Walker BD; West AP; Bjorkman PJ; Nussenzweig MC, 2017, 'Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.', Sci Transl Med, vol. 9, http://dx.doi.org/10.1126/scitranslmed.aal2144
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Gosmann C; Anahtar MN; Handley SA; Farcasanu M; Abu-Ali G; Bowman BA; Padavattan N; Desai C; Droit L; Moodley A; Dong M; Chen Y; Ismail N; Ndung'u T; Ghebremichael MS; Wesemann DR; Mitchell C; Dong KL; Huttenhower C; Walker BD; Virgin HW; Kwon DS, 2017, 'Lactobacillus-Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women.', Immunity, vol. 46, pp. 29 - 37, http://dx.doi.org/10.1016/j.immuni.2016.12.013
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Jones RB; Mueller S; Kumari S; Vrbanac V; Genel S; Tager AM; Allen TM; Walker BD; Irvine DJ, 2017, 'Antigen recognition-triggered drug delivery mediated by nanocapsule-functionalized cytotoxic T-cells.', Biomaterials, vol. 117, pp. 44 - 53, http://dx.doi.org/10.1016/j.biomaterials.2016.11.048
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Dominguez-Molina B; Tarancon-Diez L; Hua S; Abad-Molina C; Rodriguez-Gallego E; Machmach K; Vidal F; Tural C; Moreno S; Goñi JM; Ramírez de Arellano E; Del Val M; Gonzalez-Escribano MF; Del Romero J; Rodriguez C; Capa L; Viciana P; Alcamí J; Yu XG; Walker BD; Leal M; Lichterfeld M; Ruiz-Mateos E; ECRIS integrated in the Spanish AIDS Research Network , 2017, 'HLA-B*57 and IFNL4-related polymorphisms are associated with protection against HIV-1 disease progression in controllers.', Clin Infect Dis, vol. 64, pp. 621 - 628, http://dx.doi.org/10.1093/cid/ciw833
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Park RJ; Wang T; Koundakjian D; Hultquist JF; Lamothe-Molina P; Monel B; Schumann K; Yu H; Krupzcak KM; Garcia-Beltran W; Piechocka-Trocha A; Krogan NJ; Marson A; Sabatini DM; Lander ES; Hacohen N; Walker BD, 2017, 'A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.', Nat Genet, vol. 49, pp. 193 - 203, http://dx.doi.org/10.1038/ng.3741
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Flerin NC; Chen H; Glover TD; Lamothe PA; Zheng JH; Fang JW; Ndhlovu ZM; Newell EW; Davis MM; Walker BD; Goldstein H, 2017, 'T-Cell Receptor (TCR) Clonotype-Specific Differences in Inhibitory Activity of HIV-1 Cytotoxic T-Cell Clones Is Not Mediated by TCR Alone.', J Virol, vol. 91, http://dx.doi.org/10.1128/JVI.02412-16
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Laher F; Ranasinghe S; Porichis F; Mewalal N; Pretorius K; Ismail N; Buus S; Stryhn A; Carrington M; Walker BD; Ndung'u T; Ndhlovu ZM, 2017, 'HIV Controllers Exhibit Enhanced Frequencies of Major Histocompatibility Complex Class II Tetramer+ Gag-Specific CD4+ T Cells in Chronic Clade C HIV-1 Infection.', J Virol, vol. 91, http://dx.doi.org/10.1128/JVI.02477-16
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Lee GQ; Orlova-Fink N; Einkauf K; Chowdhury FZ; Sun X; Harrington S; Kuo H-H; Hua S; Chen H-R; Ouyang Z; Reddy K; Dong K; Ndung'u T; Walker BD; Rosenberg ES; Yu XG; Lichterfeld M, 2017, 'Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells.', J Clin Invest, vol. 127, pp. 2689 - 2696, http://dx.doi.org/10.1172/JCI93289
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Beyrer C; Shisana O; Baral SD; Milsana K; Mayer KH; Pozniak A; Walker BD; Mboup S; Sohn AH; Serwadda D; Rees H; Dvoriak S; Warren M; Thiam S; El-Sadr WM; Hospital X; Ryan O; Thomson N; Bekker L-G, 2017, 'The science of Durban, AIDS 2016.', J Int AIDS Soc, vol. 20, pp. 21781, http://dx.doi.org/10.7448/IAS.20.1.21781
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Dugast A-S; Arnold K; Lofano G; Moore S; Hoffner M; Simek M; Poignard P; Seaman M; Suscovich TJ; Pereyra F; Walker BD; Lauffenburger D; Kwon DS; Keele BF; Alter G, 2017, 'Virus-driven Inflammation Is Associated With the Development of bNAbs in Spontaneous Controllers of HIV.', Clin Infect Dis, vol. 64, pp. 1098 - 1104, http://dx.doi.org/10.1093/cid/cix057
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Martin-Gayo E; Cronin J; Hickman T; Ouyang Z; Lindqvist M; Kolb KE; Schulze Zur Wiesch J; Cubas R; Porichis F; Shalek AK; van Lunzen J; Haddad EK; Walker BD; Kaufmann DE; Lichterfeld M; Yu XG, 2017, 'Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth.', JCI Insight, vol. 2, pp. e89574, http://dx.doi.org/10.1172/jci.insight.89574
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Li X; Lamothe PA; Walker BD; Wang J-H, 2017, 'Crystal structure of HLA-B*5801 with a TW10 HIV Gag epitope reveals a novel mode of peptide presentation.', Cell Mol Immunol, vol. 14, pp. 631 - 634, http://dx.doi.org/10.1038/cmi.2017.24
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Clayton KL; Garcia JV; Clements JE; Walker BD, 2017, 'HIV Infection of Macrophages: Implications for Pathogenesis and Cure.', Pathog Immun, vol. 2, pp. 179 - 192, http://dx.doi.org/10.20411/pai.v2i2.204
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Mabuka JM; Dugast A-S; Muema DM; Reddy T; Ramlakhan Y; Euler Z; Ismail N; Moodley A; Dong KL; Morris L; Walker BD; Alter G; Ndung'u T, 2017, 'Plasma CXCL13 but Not B Cell Frequencies in Acute HIV Infection Predicts Emergence of Cross-Neutralizing Antibodies.', Front Immunol, vol. 8, pp. 1104, http://dx.doi.org/10.3389/fimmu.2017.01104
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Thomas AS; Jones KL; Gandhi RT; McMahon DK; Cyktor JC; Chan D; Huang S-H; Truong R; Bosque A; Macedo AB; Kovacs C; Benko E; Eron JJ; Bosch RJ; Lalama CM; Simmens S; Walker BD; Mellors JW; Jones RB, 2017, 'T-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy.', PLoS Pathog, vol. 13, pp. e1006629, http://dx.doi.org/10.1371/journal.ppat.1006629
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Leitman EM; Willberg CB; Tsai M-H; Chen H; Buus S; Chen F; Riddell L; Haas D; Fellay J; Goedert JJ; Piechocka-Trocha A; Walker BD; Martin J; Deeks S; Wolinsky SM; Martinson J; Martin M; Qi Y; Sáez-Cirión A; Yang OO; Matthews PC; Carrington M; Goulder PJR, 2017, 'HLA-B*14:02-Restricted Env-Specific CD8+ T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection.', J Virol, vol. 91, http://dx.doi.org/10.1128/JVI.00544-17
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Leitman EM; Thobakgale CF; Adland E; Ansari MA; Raghwani J; Prendergast AJ; Tudor-Williams G; Kiepiela P; Hemelaar J; Brener J; Tsai M-H; Mori M; Riddell L; Luzzi G; Jooste P; Ndung'u T; Walker BD; Pybus OG; Kellam P; Naranbhai V; Matthews PC; Gall A; Goulder PJR, 2017, 'Role of HIV-specific CD8+ T cells in pediatric HIV cure strategies after widespread early viral escape.', J Exp Med, vol. 214, pp. 3239 - 3261, http://dx.doi.org/10.1084/jem.20162123
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Ndhlovu Z; Baiyegunhi O; Ndung'u T; Walker BD, 2017, 'CXCR3/CCR6 double positive germinal center T follicular helper cells (GC TFH) harbor residual virus during cART initiated during hyperacute HIV infection', Journal of Virus Eradication, vol. 3, pp. 37 - 37, http://dx.doi.org/10.1016/s2055-6640(20)30634-8
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Reddy K; Lee GQ; Walker BD; Lichterfeld MD; Ndung'u T, 2017, 'The role of APOBEC 3G/3F in shaping early HIV-1 reservoir landscapes', Journal of Virus Eradication, vol. 3, pp. 27 - 27, http://dx.doi.org/10.1016/s2055-6640(20)30610-5
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Leitman EM; Palmer CD; Buus S; Chen F; Riddell L; Sims S; Klenerman P; Sáez-Cirión A; Walker BD; Hess PR; Altfeld M; Matthews PC; Goulder PJR, 2017, 'Saporin-conjugated tetramers identify efficacious anti-HIV CD8+ T-cell specificities.', PLoS One, vol. 12, pp. e0184496, http://dx.doi.org/10.1371/journal.pone.0184496
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Clayton K; Collins D; Lengieza J; Lieberman J; Walker B, 2017, 'Intrinsic resistance of HIV-infected macrophages to CTL-mediated killing drives immune activation', Journal of Virus Eradication, vol. 3, pp. 36 - 36, http://dx.doi.org/10.1016/s2055-6640(20)30631-2
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Laher F; Ndhlovu ZM; Baiyegunhi O; Ogunshola F; Ramsuran V; Pretorius K; Mewalal N; Nkosi T; Ismail N; Walker BD; Ndung'u T, 2017, 'Follicular regulatory T cell dynamics in peripheral blood and lymphoid tissue during very early treatment initiation in HIV-1 clade C infection', Journal of Virus Eradication, vol. 3, pp. 31 - 31, http://dx.doi.org/10.1016/s2055-6640(20)30547-1
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Clayton KL; Garcia V; Clements JE; Walker BD, 2017, 'HIV Infection of Macrophages: Implications for Pathogenesis and Cure', Pathogens and Immunity, vol. 2, pp. 179 - 179, http://dx.doi.org/10.20411/10.20411/pai.v2i2.204
    Journal articles | 2017
    Dr Bruce Duncan Walker
    Walker B, 2017, 'A-102 Impact of treatment in Fiebig Stage I on HIV-specific immune responses', JAIDS Journal of Acquired Immune Deficiency Syndromes, vol. 74, pp. 34 - 34, http://dx.doi.org/10.1097/01.qai.0000513812.50347.4c
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Gandhi RT; Kwon DS; Macklin EA; Shopis JR; McLean AP; McBrine N; Flynn T; Peter L; Sbrolla A; Kaufmann DE; Porichis F; Walker BD; Bhardwaj N; Barouch DH; Kavanagh DG, 2016, 'Immunization of HIV-1-Infected Persons With Autologous Dendritic Cells Transfected With mRNA Encoding HIV-1 Gag and Nef: Results of a Randomized, Placebo-Controlled Clinical Trial.', J Acquir Immune Defic Syndr, vol. 71, pp. 246 - 253, http://dx.doi.org/10.1097/QAI.0000000000000852
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Mahan AE; Jennewein MF; Suscovich T; Dionne K; Tedesco J; Chung AW; Streeck H; Pau M; Schuitemaker H; Francis D; Fast P; Laufer D; Walker BD; Baden L; Barouch DH; Alter G, 2016, 'Correction: Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination.', PLoS Pathog, vol. 12, pp. e1005694, http://dx.doi.org/10.1371/journal.ppat.1005694
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Muenchhoff M; Adland E; Karimanzira O; Crowther C; Pace M; Csala A; Leitman E; Moonsamy A; McGregor C; Hurst J; Groll A; Mori M; Sinmyee S; Thobakgale C; Tudor-Williams G; Prendergast AJ; Kloverpris H; Roider J; Leslie A; Shingadia D; Brits T; Daniels S; Frater J; Willberg CB; Walker BD; Ndung'u T; Jooste P; Moore PL; Morris L; Goulder P, 2016, 'Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection.', Sci Transl Med, vol. 8, pp. 358ra125, http://dx.doi.org/10.1126/scitranslmed.aag1048
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Koofhethile CK; Ndhlovu ZM; Thobakgale-Tshabalala C; Prado JG; Ismail N; Mncube Z; Mkhize L; van der Stok M; Yende N; Walker BD; Goulder PJR; Ndung'u T, 2016, 'CD8+ T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles.', J Virol, vol. 90, pp. 6818 - 6831, http://dx.doi.org/10.1128/JVI.00276-16
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Mahan AE; Jennewein MF; Suscovich T; Dionne K; Tedesco J; Chung AW; Streeck H; Pau M; Schuitemaker H; Francis D; Fast P; Laufer D; Walker BD; Baden L; Barouch DH; Alter G, 2016, 'Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination.', PLoS Pathog, vol. 12, pp. e1005456, http://dx.doi.org/10.1371/journal.ppat.1005456
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Apps R; Del Prete GQ; Chatterjee P; Lara A; Brumme ZL; Brockman MA; Neil S; Pickering S; Schneider DK; Piechocka-Trocha A; Walker BD; Thomas R; Shaw GM; Hahn BH; Keele BF; Lifson JD; Carrington M, 2016, 'HIV-1 Vpu Mediates HLA-C Downregulation.', Cell Host Microbe, vol. 19, pp. 686 - 695, http://dx.doi.org/10.1016/j.chom.2016.04.005
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Tully DC; Ogilvie CB; Batorsky RE; Bean DJ; Power KA; Ghebremichael M; Bedard HE; Gladden AD; Seese AM; Amero MA; Lane K; McGrath G; Bazner SB; Tinsley J; Lennon NJ; Henn MR; Brumme ZL; Norris PJ; Rosenberg ES; Mayer KH; Jessen H; Kosakovsky Pond SL; Walker BD; Altfeld M; Carlson JM; Allen TM, 2016, 'Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus.', PLoS Pathog, vol. 12, pp. e1005619, http://dx.doi.org/10.1371/journal.ppat.1005619
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Li X; Lamothe PA; Ng R; Xu S; Teng M; Walker BD; Wang J-H, 2016, 'Crystal structure of HLA-B*5801, a protective HLA allele for HIV-1 infection.', Protein Cell, vol. 7, pp. 761 - 765, http://dx.doi.org/10.1007/s13238-016-0309-y
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Caskey M; Klein F; Lorenzi JCC; Seaman MS; West AP; Buckley N; Kremer G; Nogueira L; Braunschweig M; Scheid JF; Horwitz JA; Shimeliovich I; Ben-Avraham S; Witmer-Pack M; Platten M; Lehmann C; Burke LA; Hawthorne T; Gorelick RJ; Walker BD; Keler T; Gulick RM; Fätkenheuer G; Schlesinger SJ; Nussenzweig MC, 2016, 'Corrigendum: Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.', Nature, vol. 535, pp. 580, http://dx.doi.org/10.1038/nature17642
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Baxter AE; Niessl J; Fromentin R; Richard J; Porichis F; Charlebois R; Massanella M; Brassard N; Alsahafi N; Delgado G-G; Routy J-P; Walker BD; Finzi A; Chomont N; Kaufmann DE, 2016, 'Single-Cell Characterization of Viral Translation-Competent Reservoirs in HIV-Infected Individuals.', Cell Host Microbe, vol. 20, pp. 368 - 380, http://dx.doi.org/10.1016/j.chom.2016.07.015
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Mahiti M; Toyoda M; Jia X; Kuang XT; Mwimanzi F; Mwimanzi P; Walker BD; Xiong Y; Brumme ZL; Brockman MA; Ueno T, 2016, 'Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences.', mBio, vol. 7, pp. e01516 - e01515, http://dx.doi.org/10.1128/mBio.01516-15
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Kløverpris HN; Kazer SW; Mjösberg J; Mabuka JM; Wellmann A; Ndhlovu Z; Yadon MC; Nhamoyebonde S; Muenchhoff M; Simoni Y; Andersson F; Kuhn W; Garrett N; Burgers WA; Kamya P; Pretorius K; Dong K; Moodley A; Newell EW; Kasprowicz V; Abdool Karim SS; Goulder P; Shalek AK; Walker BD; Ndung'u T; Leslie A, 2016, 'Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression.', Immunity, vol. 44, pp. 391 - 405, http://dx.doi.org/10.1016/j.immuni.2016.01.006
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Gunn B; Schneider J; Shansab M; Bastian AR; Fahrbach K; Smith A; Mahan A; Karim M; Licht A; Zvonar I; Tedesco J; Anderson M; Chapel A; Suscovich T; Malaspina D; Streeck H; Walker BD; Kim A; Lauer G; Altfeld M; Pillai S; Szleifer I; Kelleher NL; Kiser PF; Hope TJ; Alter G, 2016, 'Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16.', Mucosal Immunol, vol. 9, pp. 1549 - 1558, http://dx.doi.org/10.1038/mi.2016.8
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Kleinsteuber K; Corleis B; Rashidi N; Nchinda N; Lisanti A; Cho JL; Medoff BD; Kwon D; Walker BD, 2016, 'Standardization and quality control for high-dimensional mass cytometry studies of human samples.', Cytometry A, vol. 89, pp. 903 - 913, http://dx.doi.org/10.1002/cyto.a.22935
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Byrne EH; Anahtar MN; Cohen KE; Moodley A; Padavattan N; Ismail N; Bowman BA; Olson GS; Mabhula A; Leslie A; Ndung'u T; Walker BD; Ghebremichael MS; Dong KL; Kwon DS, 2016, 'Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective cohort study.', Lancet Infect Dis, vol. 16, pp. 441 - 448, http://dx.doi.org/10.1016/S1473-3099(15)00429-6
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Scheid JF; Horwitz JA; Bar-On Y; Kreider EF; Lu C-L; Lorenzi JCC; Feldmann A; Braunschweig M; Nogueira L; Oliveira T; Shimeliovich I; Patel R; Burke L; Cohen YZ; Hadrigan S; Settler A; Witmer-Pack M; West AP; Juelg B; Keler T; Hawthorne T; Zingman B; Gulick RM; Pfeifer N; Learn GH; Seaman MS; Bjorkman PJ; Klein F; Schlesinger SJ; Walker BD; Hahn BH; Nussenzweig MC; Caskey M, 2016, 'HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption.', Nature, vol. 535, pp. 556 - 560, http://dx.doi.org/10.1038/nature18929
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Jones RB; Mueller S; O'Connor R; Rimpel K; Sloan DD; Karel D; Wong HC; Jeng EK; Thomas AS; Whitney JB; Lim S-Y; Kovacs C; Benko E; Karandish S; Huang S-H; Buzon MJ; Lichterfeld M; Irrinki A; Murry JP; Tsai A; Yu H; Geleziunas R; Trocha A; Ostrowski MA; Irvine DJ; Walker BD, 2016, 'A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes.', PLoS Pathog, vol. 12, pp. e1005545, http://dx.doi.org/10.1371/journal.ppat.1005545
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Ranasinghe S; Lamothe PA; Soghoian DZ; Kazer SW; Cole MB; Shalek AK; Yosef N; Jones RB; Donaghey F; Nwonu C; Jani P; Clayton GM; Crawford F; White J; Montoya A; Power K; Allen TM; Streeck H; Kaufmann DE; Picker LJ; Kappler JW; Walker BD, 2016, 'Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion.', Immunity, vol. 45, pp. 917 - 930, http://dx.doi.org/10.1016/j.immuni.2016.09.015
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Barton JP; Goonetilleke N; Butler TC; Walker BD; McMichael AJ; Chakraborty AK, 2016, 'Relative rate and location of intra-host HIV evolution to evade cellular immunity are predictable.', Nat Commun, vol. 7, pp. 11660, http://dx.doi.org/10.1038/ncomms11660
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Sips M; Liu Q; Draghi M; Ghebremichael M; Berger CT; Suscovich TJ; Sun Y; Walker BD; Carrington M; Altfeld M; Brouckaert P; De Jager PL; Alter G, 2016, 'HLA-C levels impact natural killer cell subset distribution and function.', Hum Immunol, vol. 77, pp. 1147 - 1153, http://dx.doi.org/10.1016/j.humimm.2016.08.004
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Ackerman ME; Mikhailova A; Brown EP; Dowell KG; Walker BD; Bailey-Kellogg C; Suscovich TJ; Alter G, 2016, 'Polyfunctional HIV-Specific Antibody Responses Are Associated with Spontaneous HIV Control.', PLoS Pathog, vol. 12, pp. e1005315, http://dx.doi.org/10.1371/journal.ppat.1005315
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Havenar-Daughton C; Lindqvist M; Heit A; Wu JE; Reiss SM; Kendric K; Bélanger S; Kasturi SP; Landais E; Akondy RS; McGuire HM; Bothwell M; Vagefi PA; Scully E; IAVI Protocol C Principal Investigators ; Tomaras GD; Davis MM; Poignard P; Ahmed R; Walker BD; Pulendran B; McElrath MJ; Kaufmann DE; Crotty S, 2016, 'CXCL13 is a plasma biomarker of germinal center activity.', Proc Natl Acad Sci U S A, vol. 113, pp. 2702 - 2707, http://dx.doi.org/10.1073/pnas.1520112113
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Rucevic M; Kourjian G; Boucau J; Blatnik R; Garcia Bertran W; Berberich MJ; Walker BD; Riemer AB; Le Gall S, 2016, 'Analysis of Major Histocompatibility Complex-Bound HIV Peptides Identified from Various Cell Types Reveals Common Nested Peptides and Novel T Cell Responses.', J Virol, vol. 90, pp. 8605 - 8620, http://dx.doi.org/10.1128/JVI.00599-16
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Kinloch NN; MacMillan DR; Le AQ; Cotton LA; Bangsberg DR; Buchbinder S; Carrington M; Fuchs J; Harrigan PR; Koblin B; Kushel M; Markowitz M; Mayer K; Milloy MJ; Schechter MT; Wagner T; Walker BD; Carlson JM; Poon AFY; Brumme ZL, 2016, 'Population-Level Immune-Mediated Adaptation in HIV-1 Polymerase during the North American Epidemic.', J Virol, vol. 90, pp. 1244 - 1258, http://dx.doi.org/10.1128/JVI.02353-15
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Shasha D; Karel D; Angiuli O; Greenblatt A; Ghebremichael M; Yu X; Porichis F; Walker BD, 2016, 'Elite controller CD8+ T cells exhibit comparable viral inhibition capacity, but better sustained effector properties compared to chronic progressors.', J Leukoc Biol, vol. 100, pp. 1425 - 1433, http://dx.doi.org/10.1189/jlb.4A0915-422R
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Jones RB; Walker BD, 2016, 'HIV-specific CD8⁺ T cells and HIV eradication.', J Clin Invest, vol. 126, pp. 455 - 463, http://dx.doi.org/10.1172/JCI80566
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Lederman MM; Cannon PM; Currier JS; June CH; Kiem HP; Kuritzkes DR; Lewin SR; Margolis DM; McCune JM; Mellors JW; Schacker TW; Sekaly RP; Tebas P; Walker BD; Douek DC, 2016, 'A Cure for HIV Infection: "Not in My Lifetime" or "Just Around the Corner"?', Pathog Immun, vol. 1, pp. 154 - 164, http://dx.doi.org/10.20411/pai.v1i1.133
    Journal articles | 2016
    Dr Bruce Duncan Walker
    2016, 'Oral abstracts of the 21st International AIDS Conference 18-22 July 2016, Durban, South Africa.', J Int AIDS Soc, vol. 19, pp. 21264, http://dx.doi.org/10.7448/IAS.19.6.21264
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Leitman EM; Hurst J; Mori M; Kublin J; Ndung'u T; Walker BD; Carlson J; Gray GE; Matthews PC; Frahm N; Goulder PJR, 2016, 'Lower Viral Loads and Slower CD4+ T-Cell Count Decline in MRKAd5 HIV-1 Vaccinees Expressing Disease-Susceptible HLA-B*58:02.', J Infect Dis, vol. 214, pp. 379 - 389, http://dx.doi.org/10.1093/infdis/jiw093
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Palmer CD; Romero-Tejeda M; Scully EP; Lockhart A; Seaman MS; Goldenthal A; Piechocka-Trocha A; Walker BD; Chibnik LB; Jost S; Porichis F, 2016, 'Increased frequencies of CD8+CD57+ T cells are associated with antibody neutralization breadth against HIV in viraemic controllers.', J Int AIDS Soc, vol. 19, pp. 21136, http://dx.doi.org/10.7448/IAS.19.1.21136
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Lee W; Tay A; Walker BD; Kuchar DL; Hayward CS; Spratt P; Subbiah RN, 2016, 'Accelerated graft dysfunction in heart transplant patients with persistent atrioventricular conduction block', Europace, vol. 18, pp. 1837 - 1841, http://dx.doi.org/10.1093/europace/euv433
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Gaiha GD; Walker BD, 2016, 'CD8(+) T Cells and cART: A Dynamic Duo?', Immunity, vol. 45, pp. 466 - 468, http://dx.doi.org/10.1016/j.immuni.2016.09.003
    Journal articles | 2016
    Dr Bruce Duncan Walker
    Lee W; Tay A; Walker B; Subbiah R, 2016, 'Implantable Cardioverter Defibrillator Shock Reduction Programming Does not Reduce Likelihood of Cardiac Transplantation in Heart Failure Patients with Left Ventricular Assist Devices', Heart, Lung and Circulation, vol. 25, pp. S114 - S115, http://dx.doi.org/10.1016/j.hlc.2016.06.272
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Freund NT; Horwitz JA; Nogueira L; Sievers SA; Scharf L; Scheid JF; Gazumyan A; Liu C; Velinzon K; Goldenthal A; Sanders RW; Moore JP; Bjorkman PJ; Seaman MS; Walker BD; Klein F; Nussenzweig MC, 2015, 'A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo.', PLoS Pathog, vol. 11, pp. e1005238, http://dx.doi.org/10.1371/journal.ppat.1005238
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Adland E; Paioni P; Thobakgale C; Laker L; Mori L; Muenchhoff M; Csala A; Clapson M; Flynn J; Novelli V; Hurst J; Naidoo V; Shapiro R; Huang K-HG; Frater J; Prendergast A; Prado JG; Ndung'u T; Walker BD; Carrington M; Jooste P; Goulder PJR, 2015, 'Discordant Impact of HLA on Viral Replicative Capacity and Disease Progression in Pediatric and Adult HIV Infection.', PLoS Pathog, vol. 11, pp. e1004954, http://dx.doi.org/10.1371/journal.ppat.1004954
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Mori M; Adland E; Paioni P; Swordy A; Mori L; Laker L; Muenchhoff M; Matthews PC; Tudor-Williams G; Lavandier N; van Zyl A; Hurst J; Walker BD; Ndung'u T; Prendergast A; Goulder P; Jooste P, 2015, 'Sex Differences in Antiretroviral Therapy Initiation in Pediatric HIV Infection.', PLoS One, vol. 10, pp. e0131591, http://dx.doi.org/10.1371/journal.pone.0131591
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Heesters BA; Lindqvist M; Vagefi PA; Scully EP; Schildberg FA; Altfeld M; Walker BD; Kaufmann DE; Carroll MC, 2015, 'Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes.', PLoS Pathog, vol. 11, pp. e1005285, http://dx.doi.org/10.1371/journal.ppat.1005285
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Hölzemer A; Thobakgale CF; Jimenez Cruz CA; Garcia-Beltran WF; Carlson JM; van Teijlingen NH; Mann JK; Jaggernath M; Kang S-G; Körner C; Chung AW; Schafer JL; Evans DT; Alter G; Walker BD; Goulder PJ; Carrington M; Hartmann P; Pertel T; Zhou R; Ndung'u T; Altfeld M, 2015, 'Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa.', PLoS Med, vol. 12, pp. e1001900, http://dx.doi.org/10.1371/journal.pmed.1001900
    Journal articles | 2015
    Dr Bruce Duncan Walker
    McLaren PJ; Coulonges C; Bartha I; Lenz TL; Deutsch AJ; Bashirova A; Buchbinder S; Carrington MN; Cossarizza A; Dalmau J; De Luca A; Goedert JJ; Gurdasani D; Haas DW; Herbeck JT; Johnson EO; Kirk GD; Lambotte O; Luo M; Mallal S; van Manen D; Martinez-Picado J; Meyer L; Miro JM; Mullins JI; Obel N; Poli G; Sandhu MS; Schuitemaker H; Shea PR; Theodorou I; Walker BD; Weintrob AC; Winkler CA; Wolinsky SM; Raychaudhuri S; Goldstein DB; Telenti A; de Bakker PIW; Zagury J-F; Fellay J, 2015, 'Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load.', Proc Natl Acad Sci U S A, vol. 112, pp. 14658 - 14663, http://dx.doi.org/10.1073/pnas.1514867112
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Xu GJ; Kula T; Xu Q; Li MZ; Vernon SD; Ndung'u T; Ruxrungtham K; Sanchez J; Brander C; Chung RT; O'Connor KC; Walker B; Larman HB; Elledge SJ, 2015, 'Viral immunology. Comprehensive serological profiling of human populations using a synthetic human virome.', Science, vol. 348, pp. aaa0698, http://dx.doi.org/10.1126/science.aaa0698
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Makadzange AT; Higgins-Biddle M; Chimukangara B; Birri R; Gordon M; Mahlanza T; McHugh G; van Dijk JH; Bwakura-Dangarembizi M; Ndung'u T; Masimirembwa C; Phelps B; Amzel A; Ojikutu BO; Walker BD; Ndhlovu CE, 2015, 'Clinical, Virologic, Immunologic Outcomes and Emerging HIV Drug Resistance Patterns in Children and Adolescents in Public ART Care in Zimbabwe.', PLoS One, vol. 10, pp. e0144057, http://dx.doi.org/10.1371/journal.pone.0144057
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Chen J; Tibroni N; Sauter D; Galaski J; Miura T; Alter G; Mueller B; Haller C; Walker BD; Kirchhoff F; Brumme ZL; Ueno T; Fackler OT, 2015, 'Modest attenuation of HIV-1 Vpu alleles derived from elite controller plasma.', PLoS One, vol. 10, pp. e0120434, http://dx.doi.org/10.1371/journal.pone.0120434
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Ndhlovu ZM; Kamya P; Mewalal N; Kløverpris HN; Nkosi T; Pretorius K; Laher F; Ogunshola F; Chopera D; Shekhar K; Ghebremichael M; Ismail N; Moodley A; Malik A; Leslie A; Goulder PJR; Buus S; Chakraborty A; Dong K; Ndung'u T; Walker BD, 2015, 'Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point.', Immunity, vol. 43, pp. 591 - 604, http://dx.doi.org/10.1016/j.immuni.2015.08.012
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Vigano S; Negron J; Ouyang Z; Rosenberg ES; Walker BD; Lichterfeld M; Yu XG, 2015, 'Prolonged Antiretroviral Therapy Preserves HIV-1-Specific CD8 T Cells with Stem Cell-Like Properties.', J Virol, vol. 89, pp. 7829 - 7840, http://dx.doi.org/10.1128/JVI.00789-15
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Radebe M; Gounder K; Mokgoro M; Ndhlovu ZM; Mncube Z; Mkhize L; van der Stok M; Jaggernath M; Walker BD; Ndung'u T, 2015, 'Broad and persistent Gag-specific CD8+ T-cell responses are associated with viral control but rarely drive viral escape during primary HIV-1 infection.', AIDS, vol. 29, pp. 23 - 33, http://dx.doi.org/10.1097/QAD.0000000000000508
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Ndhlovu ZM; Stampouloglou E; Cesa K; Mavrothalassitis O; Alvino DM; Li JZ; Wilton S; Karel D; Piechocka-Trocha A; Chen H; Pereyra F; Walker BD, 2015, 'The Breadth of Expandable Memory CD8+ T Cells Inversely Correlates with Residual Viral Loads in HIV Elite Controllers.', J Virol, vol. 89, pp. 10735 - 10747, http://dx.doi.org/10.1128/JVI.01527-15
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Anahtar MN; Byrne EH; Doherty KE; Bowman BA; Yamamoto HS; Soumillon M; Padavattan N; Ismail N; Moodley A; Sabatini ME; Ghebremichael MS; Nusbaum C; Huttenhower C; Virgin HW; Ndung'u T; Dong KL; Walker BD; Fichorova RN; Kwon DS, 2015, 'Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract.', Immunity, vol. 42, pp. 965 - 976, http://dx.doi.org/10.1016/j.immuni.2015.04.019
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Ranasinghe S; Soghoian DZ; Lindqvist M; Ghebremichael M; Donaghey F; Carrington M; Seaman MS; Kaufmann DE; Walker BD; Porichis F, 2015, 'HIV-1 Antibody Neutralization Breadth Is Associated with Enhanced HIV-Specific CD4+ T Cell Responses.', J Virol, vol. 90, pp. 2208 - 2220, http://dx.doi.org/10.1128/JVI.02278-15
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Martin-Gayo E; Buzon MJ; Ouyang Z; Hickman T; Cronin J; Pimenova D; Walker BD; Lichterfeld M; Yu XG, 2015, 'Potent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers.', PLoS Pathog, vol. 11, pp. e1004930, http://dx.doi.org/10.1371/journal.ppat.1004930
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Alsahafi N; Ding S; Richard J; Markle T; Brassard N; Walker B; Lewis GK; Kaufmann DE; Brockman MA; Finzi A, 2015, 'Nef Proteins from HIV-1 Elite Controllers Are Inefficient at Preventing Antibody-Dependent Cellular Cytotoxicity.', J Virol, vol. 90, pp. 2993 - 3002, http://dx.doi.org/10.1128/JVI.02973-15
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Gounder K; Padayachi N; Mann JK; Radebe M; Mokgoro M; van der Stok M; Mkhize L; Mncube Z; Jaggernath M; Reddy T; Walker BD; Ndung'u T, 2015, 'High frequency of transmitted HIV-1 Gag HLA class I-driven immune escape variants but minimal immune selection over the first year of clade C infection.', PLoS One, vol. 10, pp. e0119886, http://dx.doi.org/10.1371/journal.pone.0119886
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Caskey M; Klein F; Lorenzi JCC; Seaman MS; West AP; Buckley N; Kremer G; Nogueira L; Braunschweig M; Scheid JF; Horwitz JA; Shimeliovich I; Ben-Avraham S; Witmer-Pack M; Platten M; Lehmann C; Burke LA; Hawthorne T; Gorelick RJ; Walker BD; Keler T; Gulick RM; Fätkenheuer G; Schlesinger SJ; Nussenzweig MC, 2015, 'Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.', Nature, vol. 522, pp. 487 - 491, http://dx.doi.org/10.1038/nature14411
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Kikuchi T; Iwabu Y; Tada T; Kawana-Tachikawa A; Koga M; Hosoya N; Nomura S; Brumme ZL; Jessen H; Pereyra F; Trocha A; Walker BD; Iwamoto A; Tokunaga K; Miura T, 2015, 'Anti-APOBEC3G activity of HIV-1 Vif protein is attenuated in elite controllers.', J Virol, vol. 89, pp. 4992 - 5001, http://dx.doi.org/10.1128/JVI.03464-14
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Adoro S; Cubillos-Ruiz JR; Chen X; Deruaz M; Vrbanac VD; Song M; Park S; Murooka TT; Dudek TE; Luster AD; Tager AM; Streeck H; Bowman B; Walker BD; Kwon DS; Lazarevic V; Glimcher LH, 2015, 'IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection.', Nat Commun, vol. 6, pp. 7562, http://dx.doi.org/10.1038/ncomms8562
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Cohn LB; Silva IT; Oliveira TY; Rosales RA; Parrish EH; Learn GH; Hahn BH; Czartoski JL; McElrath MJ; Lehmann C; Klein F; Caskey M; Walker BD; Siliciano JD; Siliciano RF; Jankovic M; Nussenzweig MC, 2015, 'HIV-1 integration landscape during latent and active infection.', Cell, vol. 160, pp. 420 - 432, http://dx.doi.org/10.1016/j.cell.2015.01.020
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Kløverpris HN; McGregor R; McLaren JE; Ladell K; Harndahl M; Stryhn A; Carlson JM; Koofhethile C; Gerritsen B; Keşmir C; Chen F; Riddell L; Luzzi G; Leslie A; Walker BD; Ndung'u T; Buus S; Price DA; Goulder PJ, 2015, 'CD8+ TCR Bias and Immunodominance in HIV-1 Infection.', J Immunol, vol. 194, pp. 5329 - 5345, http://dx.doi.org/10.4049/jimmunol.1400854
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Lee W; Tay A; Subbiah RN; Walker BD; Kuchar DL; Muthiah K; Macdonald PS; Keogh AM; Kotlyar E; Jabbour A; Spratt P; Jansz PC; Granger E; Dhital K; Hayward CS, 2015, 'Impact of Implantable Cardioverter Defibrillators on Survival of Patients with Centrifugal Left Ventricular Assist Devices', PACE - Pacing and Clinical Electrophysiology, vol. 38, pp. 925 - 933, http://dx.doi.org/10.1111/pace.12654
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Thobakgale CF; Prendergast A; Crawford H; Mkhwanazi N; Ramduth D; Reddy S; Molina C; Mncube Z; Leslie A; Prado J; Chonco F; Mphatshwe W; Tudor-Williams G; Jeena P; Blanckenberg N; Dong K; Kiepiela P; Coovadia H; Ndung'u T; Walker BD; Goulder PJR, 2015, 'Correction for Thobakgale et al., Impact of HLA in Mother and Child on Disease Progression of Pediatric Human Immunodeficiency Virus Type 1 Infection.', J Virol, vol. 89, pp. 8101, http://dx.doi.org/10.1128/JVI.00876-15
    Journal articles | 2015
    Dr Bruce Duncan Walker
    Ogunshola F; Mewala N; Wright JK; Ismail N; Brockman MA; Walker BD; Ndung’u T; Ndhlovu ZM, 2015, 'P15.03 Development of a new cem reporter t-cells (gxr-cells) viral inhibition assay (via) for elucidating the role of class-i-hla alleles on the inhibitory capacity of hiv-1-specific cd8+t-cells', Sexually Transmitted Infections, vol. 91, pp. A210.2 - A210, http://dx.doi.org/10.1136/sextrans-2015-052270.544
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Wang LW; Walker BD; Omari A; Tay AE; Subbiah RN, 2014, 'Metastatic Merkel cell carcinoma of the heart', European Heart Journal, vol. 35, pp. 2927 - 2927, http://dx.doi.org/10.1093/eurheartj/ehu147
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Xia Z; Chen H; Kang S-G; Huynh T; Fang JW; Lamothe PA; Walker BD; Zhou R, 2014, 'The complex and specific pMHC interactions with diverse HIV-1 TCR clonotypes reveal a structural basis for alterations in CTL function.', Sci Rep, vol. 4, pp. 4087, http://dx.doi.org/10.1038/srep04087
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Bashirova AA; Martin-Gayo E; Jones DC; Qi Y; Apps R; Gao X; Burke PS; Taylor CJ; Rogich J; Wolinsky S; Bream JH; Duggal P; Hussain S; Martinson J; Weintrob A; Kirk GD; Fellay J; Buchbinder SP; Goedert JJ; Deeks SG; Pereyra F; Trowsdale J; Lichterfeld M; Telenti A; Walker BD; Allen RL; Carrington M; Yu XG, 2014, 'LILRB2 interaction with HLA class I correlates with control of HIV-1 infection.', PLoS Genet, vol. 10, pp. e1004196, http://dx.doi.org/10.1371/journal.pgen.1004196
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Gaiha GD; McKim KJ; Woods M; Pertel T; Rohrbach J; Barteneva N; Chin CR; Liu D; Soghoian DZ; Cesa K; Wilton S; Waring MT; Chicoine A; Doering T; Wherry EJ; Kaufmann DE; Lichterfeld M; Brass AL; Walker BD, 2014, 'Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis.', Immunity, vol. 41, pp. 1001 - 1012, http://dx.doi.org/10.1016/j.immuni.2014.12.011
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Cotton LA; Kuang XT; Le AQ; Carlson JM; Chan B; Chopera DR; Brumme CJ; Markle TJ; Martin E; Shahid A; Anmole G; Mwimanzi P; Nassab P; Penney KA; Rahman MA; Milloy M-J; Schechter MT; Markowitz M; Carrington M; Walker BD; Wagner T; Buchbinder S; Fuchs J; Koblin B; Mayer KH; Harrigan PR; Brockman MA; Poon AFY; Brumme ZL, 2014, 'Genotypic and functional impact of HIV-1 adaptation to its host population during the North American epidemic.', PLoS Genet, vol. 10, pp. e1004295, http://dx.doi.org/10.1371/journal.pgen.1004295
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Kuang XT; Li X; Anmole G; Mwimanzi P; Shahid A; Le AQ; Chong L; Qian H; Miura T; Markle T; Baraki B; Connick E; Daar ES; Jessen H; Kelleher AD; Little S; Markowitz M; Pereyra F; Rosenberg ES; Walker BD; Ueno T; Brumme ZL; Brockman MA, 2014, 'Impaired Nef function is associated with early control of HIV-1 viremia', Journal of Virology, vol. 88, pp. 10200 - 10213, http://dx.doi.org/10.1128/JVI.01334-14
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Angin M; Sharma S; King M; Murooka TT; Ghebremichael M; Mempel TR; Walker BD; Bhasin MK; Addo MM, 2014, 'HIV-1 infection impairs regulatory T-cell suppressive capacity on a per-cell basis.', J Infect Dis, vol. 210, pp. 899 - 903, http://dx.doi.org/10.1093/infdis/jiu188
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Payne RP; Branch S; Kløverpris H; Matthews PC; Koofhethile CK; Strong T; Adland E; Leitman E; Frater J; Ndung'u T; Hunter E; Haubrich R; Mothe B; Edwards A; Riddell L; Chen F; Harrigan PR; Brumme ZL; Mallal S; John M; Jooste JP; Shapiro R; Deeks SG; Walker BD; Brander C; Landis C; Carlson JM; Prado JG; Goulder PJR, 2014, 'Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints.', J Virol, vol. 88, pp. 4668 - 4678, http://dx.doi.org/10.1128/JVI.03303-13
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Buzon MJ; Sun H; Li C; Shaw A; Seiss K; Ouyang Z; Martin-Gayo E; Leng J; Henrich TJ; Li JZ; Pereyra F; Zurakowski R; Walker BD; Rosenberg ES; Yu XG; Lichterfeld M, 2014, 'HIV-1 persistence in CD4+ T cells with stem cell-like properties.', Nat Med, vol. 20, pp. 139 - 142, http://dx.doi.org/10.1038/nm.3445
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Buzon MJ; Martin-Gayo E; Pereyra F; Ouyang Z; Sun H; Li JZ; Piovoso M; Shaw A; Dalmau J; Zangger N; Martinez-Picado J; Zurakowski R; Yu XG; Telenti A; Walker BD; Rosenberg ES; Lichterfeld M, 2014, 'Long-term antiretroviral treatment initiated at primary HIV-1 infection affects the size, composition, and decay kinetics of the reservoir of HIV-1-infected CD4 T cells.', J Virol, vol. 88, pp. 10056 - 10065, http://dx.doi.org/10.1128/JVI.01046-14
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Pereyra F; Heckerman D; Carlson JM; Kadie C; Soghoian DZ; Karel D; Goldenthal A; Davis OB; DeZiel CE; Lin T; Peng J; Piechocka A; Carrington M; Walker BD, 2014, 'HIV control is mediated in part by CD8+ T-cell targeting of specific epitopes.', J Virol, vol. 88, pp. 12937 - 12948, http://dx.doi.org/10.1128/JVI.01004-14
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Payne R; Muenchhoff M; Mann J; Roberts HE; Matthews P; Adland E; Hempenstall A; Huang K-H; Brockman M; Brumme Z; Sinclair M; Miura T; Frater J; Essex M; Shapiro R; Walker BD; Ndung'u T; McLean AR; Carlson JM; Goulder PJR, 2014, 'Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence.', Proc Natl Acad Sci U S A, vol. 111, pp. E5393 - E5400, http://dx.doi.org/10.1073/pnas.1413339111
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Jones RB; O'Connor R; Mueller S; Foley M; Szeto GL; Karel D; Lichterfeld M; Kovacs C; Ostrowski MA; Trocha A; Irvine DJ; Walker BD, 2014, 'Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes.', PLoS Pathog, vol. 10, pp. e1004287, http://dx.doi.org/10.1371/journal.ppat.1004287
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Foley MH; Forcier T; McAndrew E; Gonzalez M; Chen H; Juelg B; Walker BD; Irvine DJ, 2014, 'High avidity CD8+ T cells efficiently eliminate motile HIV-infected targets and execute a locally focused program of anti-viral function.', PLoS One, vol. 9, pp. e87873, http://dx.doi.org/10.1371/journal.pone.0087873
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Mann JK; Chopera D; Omarjee S; Kuang XT; Le AQ; Anmole G; Danroth R; Mwimanzi P; Reddy T; Carlson J; Radebe M; Goulder PJR; Walker BD; Abdool Karim S; Novitsky V; Williamson C; Brockman MA; Brumme ZL; Ndung'u T, 2014, 'Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: association with disease progression and influence of immune pressure.', Virology, vol. 468-470, pp. 214 - 225, http://dx.doi.org/10.1016/j.virol.2014.08.009
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Leng J; Ho H-P; Buzon MJ; Pereyra F; Walker BD; Yu XG; Chang EJ; Lichterfeld M, 2014, 'A cell-intrinsic inhibitor of HIV-1 reverse transcription in CD4(+) T cells from elite controllers.', Cell Host Microbe, vol. 15, pp. 717 - 728, http://dx.doi.org/10.1016/j.chom.2014.05.011
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Kløverpris HN; Adland E; Koyanagi M; Stryhn A; Harndahl M; Matthews PC; Shapiro R; Walker BD; Ndung'u T; Brander C; Takiguchi M; Buus S; Goulder P, 2014, 'HIV subtype influences HLA-B*07:02-associated HIV disease outcome.', AIDS Res Hum Retroviruses, vol. 30, pp. 468 - 475, http://dx.doi.org/10.1089/AID.2013.0197
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Cheruvu C; Walker B; Kuchar D; Subbiah RN, 2014, 'Successful Ablation of Incessant AV Reentrant Tachycardia in a Patient on Extracorporeal Membrane Oxygenation', Heart, Lung and Circulation, vol. 23, pp. e12 - e15, http://dx.doi.org/10.1016/j.hlc.2013.06.011
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Mann JK; Barton JP; Ferguson AL; Omarjee S; Walker BD; Chakraborty A; Ndung'u T, 2014, 'The fitness landscape of HIV-1 gag: advanced modeling approaches and validation of model predictions by in vitro testing.', PLoS Comput Biol, vol. 10, pp. e1003776, http://dx.doi.org/10.1371/journal.pcbi.1003776
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Dugast AS; Arnold K; Hoffner M; Pereyra F; Seaman M; Walker B; Lauffenburger D; Alter G, 2014, 'An Inflammatory Profile that Predicts the Development of Neutralizing Antibody Breadth', AIDS Research and Human Retroviruses, vol. 30, pp. A35 - A36, http://dx.doi.org/10.1089/aid.2014.5057.abstract
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Mabuka JK; Dugast A-S; Euler Z; Ramlakhan Y; Dong K; Walker BD; Ndung'u T; Alter G, 2014, 'Acute HIV-1 Subtype C Infection Is Associated with Rapid Increase of Tissue-like Memory and Decrease in Resting Memory B-cells', AIDS Research and Human Retroviruses, vol. 30, pp. A211 - A211, http://dx.doi.org/10.1089/aid.2014.5457b.abstract
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Ndlovu BG; Chung A; Maroa J; Walker BD; Alter G; Ndung'u T, 2014, 'Gp41 and p24 IgG Binding Antibody Titers Are Associated with HIV-1 Viral Control during Early HIV-1 Subtype C Infection', AIDS Research and Human Retroviruses, vol. 30, pp. A248 - A248, http://dx.doi.org/10.1089/aid.2014.5552.abstract
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Ranasinghe S; Davis I; Soghoian D; Lamothe P; Sidney J; Sette A; Carrington M; Streeck H; Picker L; Kaufmann D; Walker B, 2014, 'Paradigm-violating HLA Class II-restricted CD8 T-cells in HIV-infection', AIDS Research and Human Retroviruses, vol. 30, pp. A75 - A75, http://dx.doi.org/10.1089/aid.2014.5140.abstract
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Martin-Gayo E; Hickman T; Ouyang Z; Cubas R; Lindqvist M; Kauffman D; Haddad E; Walker B; Lichterfeld M; Yu XG, 2014, 'Dendritic Cells from HIV-1 Neutralizers Efficiently Induce the Generation of CXCR5+ CXCR3+ PD1Lo CD4 T Cells with B Cell Helper Function', AIDS Research and Human Retroviruses, vol. 30, pp. A74 - A74, http://dx.doi.org/10.1089/aid.2014.5137.abstract
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Byrne EH; Anahtar M; Doherty K; Olson G; Bowman B; Padavattan N; Ndhlovu Z; Ghebremichael M; Walker B; Ndung'u T; Dong K; Kwon DS, 2014, 'Injectable Contraceptive Use Correlates with Increased HIV Target Cells at the Cervix in Young South African Women', AIDS Research and Human Retroviruses, vol. 30, pp. A54 - A55, http://dx.doi.org/10.1089/aid.2014.5096.abstract
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Chetty S; Porichis F; Govender P; Zupkosky J; Ghebremichael M; Pillay M; Walker BD; Ndung'u T; Kaufmann DE; Kasprowicz VO, 2014, 'Tuberculosis distorts the inhibitory impact of interleukin-10 in HIV infection.', AIDS, vol. 28, pp. 2671 - 2676, http://dx.doi.org/10.1097/QAD.0000000000000437
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Laher F; Ranasinghe S; Porichis F; Davis I; Mavrothalassitis O; Ismail N; Mewalal N; Mahungela S; Walker BD; Ndung'u T; Ndhlovu ZM, 2014, 'Differences in Immunodominant Patterns and HLA-DRB1 Restriction Characteristics in HIV-specific CD4 T-cell Responses between Clade B and C Infection', AIDS Research and Human Retroviruses, vol. 30, pp. A177 - A177, http://dx.doi.org/10.1089/aid.2014.5375.abstract
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Doherty KE; Anahtar M; Ghebremichael M; Thogabekale C; Padavattan N; Dong K; Walker BD; Ndung'u T; Kwon DS, 2014, 'Effects of Intra-vaginal Drying Agents on Mucosal Immune Activation and Risk for HIV Acquisition in South African Women', AIDS Research and Human Retroviruses, vol. 30, pp. A230 - A231, http://dx.doi.org/10.1089/aid.2014.5506.abstract
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Ndhlovu Z; Kamya P; Mewalal N; Nkosi T; Ismail N; Moodley A; Dong K; Ndung'u T; Walker B, 2014, 'Massive Activation, Expansion and Subsequent Apoptosis of CD8 T-cells in Acute HIV Infection', AIDS Research and Human Retroviruses, vol. 30, pp. A74 - A75, http://dx.doi.org/10.1089/aid.2014.5138.abstract
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Kløverpris HN; Noorbhai A; Kuhn W; Yadon M; Ramsuran D; Nhamoyebonde S; Kasprowicz V; Walker B; Ndung'u T; Goulder P; Karim AS; Mjösberg J; Leslie A, 2014, 'Innate Lymphoid Cells Are Depleted in HIV Infection', AIDS Research and Human Retroviruses, vol. 30, pp. A14 - A14, http://dx.doi.org/10.1089/aid.2014.5015.abstract
    Journal articles | 2014
    Dr Bruce Duncan Walker
    Kay MA; Walker BD, 2014, 'Engineering cellular resistance to HIV.', N Engl J Med, vol. 370, pp. 968 - 969, http://dx.doi.org/10.1056/NEJMe1400593
    Journal articles | 2013
    Dr Bruce Duncan Walker
    McLaren PJ; Coulonges C; Ripke S; van den Berg L; Buchbinder S; Carrington M; Cossarizza A; Dalmau J; Deeks SG; Delaneau O; De Luca A; Goedert JJ; Haas D; Herbeck JT; Kathiresan S; Kirk GD; Lambotte O; Luo M; Mallal S; van Manen D; Martinez-Picado J; Meyer L; Miro JM; Mullins JI; Obel N; O'Brien SJ; Pereyra F; Plummer FA; Poli G; Qi Y; Rucart P; Sandhu MS; Shea PR; Schuitemaker H; Theodorou I; Vannberg F; Veldink J; Walker BD; Weintrob A; Winkler CA; Wolinsky S; Telenti A; Goldstein DB; de Bakker PIW; Zagury J-F; Fellay J, 2013, 'Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls', PLOS PATHOGENS, vol. 9, http://dx.doi.org/10.1371/journal.ppat.1003515
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Wong EB; Akilimali NA; Govender P; Sullivan ZA; Cosgrove C; Pillay M; Lewinsohn DM; Bishai WR; Walker BD; Ndung'u T; Klenerman P; Kasprowicz VO, 2013, 'Low levels of peripheral CD161++CD8+ mucosal associated invariant T (MAIT) cells are found in HIV and HIV/TB co-infection.', PLoS One, vol. 8, pp. e83474, http://dx.doi.org/10.1371/journal.pone.0083474
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Ndhlovu ZM; Chibnik LB; Proudfoot J; Vine S; McMullen A; Cesa K; Porichis F; Jones RB; Alvino DM; Hart MG; Stampouloglou E; Piechocka-Trocha A; Kadie C; Pereyra F; Heckerman D; De Jager PL; Walker BD; Kaufmann DE, 2013, 'High-dimensional immunomonitoring models of HIV-1-specific CD8 T-cell responses accurately identify subjects achieving spontaneous viral control.', Blood, vol. 121, pp. 801 - 811, http://dx.doi.org/10.1182/blood-2012-06-436295
    Journal articles | 2013
    Dr Bruce Duncan Walker
    LEE WILLIAM; KUCHAR DENNISL; WALKER BRUCED; SUBBIAH RAJESHN, 2013, 'Isolated Ventricular Noncompaction: Implications for Mechanisms of Sudden Cardiac Death', Pacing and Clinical Electrophysiology, vol. 36, pp. e153 - e155, http://dx.doi.org/10.1111/j.1540-8159.2012.03344.x
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Mwimanzi P; Markle TJ; Ogata Y; Martin E; Tokunaga M; Mahiti M; Kuang XT; Walker BD; Brockman MA; Brumme ZL; Ueno T, 2013, 'Dynamic range of Nef functions in chronic HIV-1 infection.', Virology, vol. 439, pp. 74 - 80, http://dx.doi.org/10.1016/j.virol.2013.02.005
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Adland E; Carlson JM; Paioni P; Kløverpris H; Shapiro R; Ogwu A; Riddell L; Luzzi G; Chen F; Balachandran T; Heckerman D; Stryhn A; Edwards A; Ndung'u T; Walker BD; Buus S; Goulder P; Matthews PC, 2013, 'Nef-specific CD8+ T cell responses contribute to HIV-1 immune control.', PLoS One, vol. 8, pp. e73117, http://dx.doi.org/10.1371/journal.pone.0073117
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Walker BD; Yu XG, 2013, 'Unravelling the mechanisms of durable control of HIV-1.', Nat Rev Immunol, vol. 13, pp. 487 - 498, http://dx.doi.org/10.1038/nri3478
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Youngblood B; Noto A; Porichis F; Akondy RS; Ndhlovu ZM; Austin JW; Bordi R; Procopio FA; Miura T; Allen TM; Sidney J; Sette A; Walker BD; Ahmed R; Boss JM; Sékaly R-P; Kaufmann DE, 2013, 'Cutting edge: Prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells.', J Immunol, vol. 191, pp. 540 - 544, http://dx.doi.org/10.4049/jimmunol.1203161
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Mann JK; Byakwaga H; Kuang XT; Le AQ; Brumme CJ; Mwimanzi P; Omarjee S; Martin E; Lee GQ; Baraki B; Danroth R; McCloskey R; Muzoora C; Bangsberg DR; Hunt PW; Goulder PJR; Walker BD; Harrigan PR; Martin JN; Ndung'u T; Brockman MA; Brumme ZL, 2013, 'Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes', RETROVIROLOGY, vol. 10, http://dx.doi.org/10.1186/1742-4690-10-100
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Koff WC; Russell ND; Walport M; Feinberg MB; Shiver JW; Karim SA; Walker BD; McGlynn MG; Nweneka CV; Nabel GJ, 2013, 'Accelerating the development of a safe and effective HIV vaccine: HIV vaccine case study for the Decade of Vaccines.', Vaccine, vol. 31 Suppl 2, pp. B204 - B208, http://dx.doi.org/10.1016/j.vaccine.2012.10.115
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Kløverpris HN; Stryhn A; Harndahl M; Payne R; Towers GJ; Chen F; Riddell L; Walker BD; Ndung'u T; Leslie A; Buus S; Goulder P, 2013, 'HLA-specific intracellular epitope processing shapes an immunodominance pattern for HLA-B*57 that is distinct from HLA-B*58:01.', J Virol, vol. 87, pp. 10889 - 10894, http://dx.doi.org/10.1128/JVI.01122-13
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Mwimanzi P; Markle TJ; Martin E; Ogata Y; Kuang XT; Tokunaga M; Mahiti M; Pereyra F; Miura T; Walker BD; Brumme ZL; Brockman MA; Ueno T, 2013, 'Attenuation of multiple Nef functions in HIV-1 elite controllers.', Retrovirology, vol. 10, pp. 1, http://dx.doi.org/10.1186/1742-4690-10-1
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Shasha D; Walker BD, 2013, 'Lessons to be Learned from Natural Control of HIV - Future Directions, Therapeutic, and Preventive Implications.', Front Immunol, vol. 4, pp. 162, http://dx.doi.org/10.3389/fimmu.2013.00162
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Kulkarni S; Qi Y; O'hUigin C; Pereyra F; Ramsuran V; McLaren P; Fellay J; Nelson G; Chen H; Liao W; Bass S; Apps R; Gao X; Yuki Y; Lied A; Ganesan A; Hunt PW; Deeks SG; Wolinsky S; Walker BD; Carrington M, 2013, 'Genetic interplay between HLA-C and MIR148A in HIV control and Crohn disease.', Proc Natl Acad Sci U S A, vol. 110, pp. 20705 - 20710, http://dx.doi.org/10.1073/pnas.1312237110
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Apps R; Qi Y; Carlson JM; Chen H; Gao X; Thomas R; Yuki Y; Del Prete GQ; Goulder P; Brumme ZL; Brumme CJ; John M; Mallal S; Nelson G; Bosch R; Heckerman D; Stein JL; Soderberg KA; Moody MA; Denny TN; Zeng X; Fang J; Moffett A; Lifson JD; Goedert JJ; Buchbinder S; Kirk GD; Fellay J; McLaren P; Deeks SG; Pereyra F; Walker B; Michael NL; Weintrob A; Wolinsky S; Liao W; Carrington M, 2013, 'Influence of HLA-C expression level on HIV control.', Science, vol. 340, pp. 87 - 91, http://dx.doi.org/10.1126/science.1232685
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Ferguson AL; Mann JK; Omarjee S; Ndung'u T; Walker BD; Chakraborty AK, 2013, 'Translating HIV sequences into quantitative fitness landscapes predicts viral vulnerabilities for rational immunogen design.', Immunity, vol. 38, pp. 606 - 617, http://dx.doi.org/10.1016/j.immuni.2012.11.022
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Ranasinghe S; Cutler S; Davis I; Lu R; Soghoian DZ; Qi Y; Sidney J; Kranias G; Flanders MD; Lindqvist M; Kuhl B; Alter G; Deeks SG; Walker BD; Gao X; Sette A; Carrington M; Streeck H, 2013, 'Association of HLA-DRB1-restricted CD4⁺ T cell responses with HIV immune control.', Nat Med, vol. 19, pp. 930 - 933, http://dx.doi.org/10.1038/nm.3229
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Kløverpris HN; Stryhn A; Harndahl M; Carlson JM; Leslie AJ; Chen F; Riddell L; Mulenga J; Walker BD; Ndung'u T; Buus S; Goulder P, 2013, 'HLA-A*68:02-restricted Gag-specific cytotoxic T lymphocyte responses can drive selection pressure on HIV but are subdominant and ineffective.', AIDS, vol. 27, pp. 1717 - 1723, http://dx.doi.org/10.1097/QAD.0b013e32836146cd
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Spina R; Granger E; Walker B; Subbiah RN, 2013, 'Ventricular tachycardia in hypertrophic cardiomyopathy with apical aneurysm successfully treated with left ventricular aneurysmectomy and cryoablation', European Heart Journal, vol. 34, pp. 3631, http://dx.doi.org/10.1093/eurheartj/eht443
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Jackson A; Kløverpris HN; Boffito M; Handley A; Atkins M; Hayes P; Gilmour J; Riddel L; Chen F; Bailey-Tippets M; Walker B; Ackland J; Sullivan M; Goulder P, 2013, 'A randomised, placebo-controlled, first-in-human study of a novel clade C therapeutic peptide vaccine administered ex vivo to autologous white blood cells in HIV infected individuals.', PLoS One, vol. 8, pp. e73765, http://dx.doi.org/10.1371/journal.pone.0073765
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Kløverpris HN; Jackson A; Handley A; Hayes P; Gilmour J; Riddell L; Chen F; Atkins M; Boffito M; Walker BD; Ackland J; Sullivan M; Goulder P, 2013, 'Non-immunogenicity of overlapping gag peptides pulsed on autologous cells after vaccination of HIV infected individuals.', PLoS One, vol. 8, pp. e74389, http://dx.doi.org/10.1371/journal.pone.0074389
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Mahiti M; Mwimanzi P; Ogata Y; Walker B; Brumme Z; Brockman M; Ueno T, 2013, 'Naturally-arising amino acid polymorphisms of HIV-1 Nef that differentially modulate downregulation of HLA-A and HLA-B molecules', Retrovirology, vol. 10, http://dx.doi.org/10.1186/1742-4690-10-s1-p54
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Pellegrini M; Walker BD, 2013, 'Host pathogen interactions at the coalface of immunity.', Curr Opin Immunol, vol. 25, pp. 425 - 427, http://dx.doi.org/10.1016/j.coi.2013.05.015
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Ranasinghe S; Walker BD, 2013, 'Programming CMV for vaccine vector design.', Nat Biotechnol, vol. 31, pp. 811 - 812, http://dx.doi.org/10.1038/nbt.2688
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Nayyar D; Feneley M; Macdonald P; Keogh A; Kotlyar E; Walker R; Hayward C, 2013, 'Non-invasive Determination of the Preload Recruitable Stroke Work Relationship in Patients with Heart Failure', Heart, Lung and Circulation, vol. 22, pp. S84, http://dx.doi.org/10.1016/j.hlc.2013.05.200
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Cheruvu C; Hugiol R; Grabs A; Thorburn C; Kuchar D; Walker B; Subbiah R, 2013, 'Refractory long QT syndrome and the role of left cardiac sympathetic denervation', Internal Medicine Journal, vol. 43, pp. 458 - 461, http://dx.doi.org/10.1111/imj.12090
    Journal articles | 2013
    Dr Bruce Duncan Walker
    Lee W; Tay A; Subbiah R; Walker B; Kuchar D; Muthiah K; Robson D; Hodkinson E; Macdonald P; Keogh A; Kotlyar E; Jabbour A; Spratt P; Granger E; Dhital K; Jansz P; Hayward C, 2013, 'Impact of Implantable Cardioverter Defibrillators on Survival of Patients with Centrifugal Left Ventricular Assist Devices', Heart, Lung and Circulation, vol. 22, pp. S79, http://dx.doi.org/10.1016/j.hlc.2013.05.188
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Wright JK; Brumme ZL; Julg B; van der Stok M; Mncube Z; Gao X; Carlson JM; Goulder PJR; Walker BD; Brockman MA; Ndung'u T, 2012, 'Lack of association between HLA class II alleles and in vitro replication capacities of recombinant viruses encoding HIV-1 subtype C Gag-protease from chronically infected individuals.', J Virol, vol. 86, pp. 1273 - 1276, http://dx.doi.org/10.1128/JVI.06533-11
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Kloverpris HN; Stryhn A; Harndahl M; van der Stok M; Payne RP; Matthews PC; Chen F; Riddell L; Walker BD; Ndung'u T; Buus S; Goulder P, 2012, 'HLA-B*57 Micropolymorphism shapes HLA allele-specific epitope immunogenicity, selection pressure, and HIV immune control.', J Virol, vol. 86, pp. 919 - 929, http://dx.doi.org/10.1128/JVI.06150-11
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Walker B; McMichael A, 2012, 'The T-cell response to HIV.', Cold Spring Harb Perspect Med, vol. 2, http://dx.doi.org/10.1101/cshperspect.a007054
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Matthews PC; Listgarten J; Carlson JM; Payne R; Huang K-HG; Frater J; Goedhals D; Steyn D; van Vuuren C; Paioni P; Jooste P; Ogwu A; Shapiro R; Mncube Z; Ndung'u T; Walker BD; Heckerman D; Goulder PJR, 2012, 'Co-operative additive effects between HLA alleles in control of HIV-1.', PLoS One, vol. 7, pp. e47799, http://dx.doi.org/10.1371/journal.pone.0047799
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Jia M; Hong K; Chen J; Ruan Y; Wang Z; Su B; Ren G; Zhang X; Liu Z; Zhao Q; Li D; Peng H; Altfeld M; Walker BD; Yu XG; Shao Y, 2012, 'Preferential CTL targeting of Gag is associated with relative viral control in long-term surviving HIV-1 infected former plasma donors from China.', Cell Res, vol. 22, pp. 903 - 914, http://dx.doi.org/10.1038/cr.2012.19
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Carrington M; Walker BD, 2012, 'Immunogenetics of spontaneous control of HIV.', Annu Rev Med, vol. 63, pp. 131 - 145, http://dx.doi.org/10.1146/annurev-med-062909-130018
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Kløverpris HN; Harndahl M; Leslie AJ; Carlson JM; Ismail N; van der Stok M; Huang K-HG; Chen F; Riddell L; Steyn D; Goedhals D; van Vuuren C; Frater J; Walker BD; Carrington M; Ndung'u T; Buus S; Goulder P, 2012, 'HIV control through a single nucleotide on the HLA-B locus.', J Virol, vol. 86, pp. 11493 - 11500, http://dx.doi.org/10.1128/JVI.01020-12
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Goulder PJR; Walker BD, 2012, 'HIV and HLA class I: an evolving relationship.', Immunity, vol. 37, pp. 426 - 440, http://dx.doi.org/10.1016/j.immuni.2012.09.005
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Julg B; Poole D; Ghebremichael M; Castilla C; Altfeld M; Sunpath H; Murphy RA; Walker BD, 2012, 'Factors predicting discordant virological and immunological responses to antiretroviral therapy in HIV-1 clade C infected Zulu/Xhosa in South Africa.', PLoS One, vol. 7, pp. e31161, http://dx.doi.org/10.1371/journal.pone.0031161
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Angin M; Kwon DS; Streeck H; Wen F; King M; Rezai A; Law K; Hongo TC; Pyo A; Piechocka-Trocha A; Toth I; Pereyra F; Ghebremichael M; Rodig SJ; Milner DA; Richter JM; Altfeld M; Kaufmann DE; Walker BD; Addo MM, 2012, 'Preserved function of regulatory T cells in chronic HIV-1 infection despite decreased numbers in blood and tissue.', J Infect Dis, vol. 205, pp. 1495 - 1500, http://dx.doi.org/10.1093/infdis/jis236
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Chang JJ; Lacas A; Lindsay RJ; Doyle EH; Axten KL; Pereyra F; Rosenberg ES; Walker BD; Allen TM; Altfeld M, 2012, 'Differential regulation of toll-like receptor pathways in acute and chronic HIV-1 infection.', AIDS, vol. 26, pp. 533 - 541, http://dx.doi.org/10.1097/QAD.0b013e32834f3167
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Burton DR; Ahmed R; Barouch DH; Butera ST; Crotty S; Godzik A; Kaufmann DE; McElrath MJ; Nussenzweig MC; Pulendran B; Scanlan CN; Schief WR; Silvestri G; Streeck H; Walker BD; Walker LM; Ward AB; Wilson IA; Wyatt R, 2012, 'A Blueprint for HIV Vaccine Discovery.', Cell Host Microbe, vol. 12, pp. 396 - 407, http://dx.doi.org/10.1016/j.chom.2012.09.008
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Henn MR; Boutwell CL; Charlebois P; Lennon NJ; Power KA; Macalalad AR; Berlin AM; Malboeuf CM; Ryan EM; Gnerre S; Zody MC; Erlich RL; Green LM; Berical A; Wang Y; Casali M; Streeck H; Bloom AK; Dudek T; Tully D; Newman R; Axten KL; Gladden AD; Battis L; Kemper M; Zeng Q; Shea TP; Gujja S; Zedlack C; Gasser O; Brander C; Hess C; Günthard HF; Brumme ZL; Brumme CJ; Bazner S; Rychert J; Tinsley JP; Mayer KH; Rosenberg E; Pereyra F; Levin JZ; Young SK; Jessen H; Altfeld M; Birren BW; Walker BD; Allen TM, 2012, 'Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection.', PLoS Pathog, vol. 8, pp. e1002529, http://dx.doi.org/10.1371/journal.ppat.1002529
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Chen H; Ndhlovu ZM; Liu D; Porter LC; Fang JW; Darko S; Brockman MA; Miura T; Brumme ZL; Schneidewind A; Piechocka-Trocha A; Cesa KT; Sela J; Cung TD; Toth I; Pereyra F; Yu XG; Douek DC; Kaufmann DE; Allen TM; Walker BD, 2012, 'TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection.', Nat Immunol, vol. 13, pp. 691 - 700, http://dx.doi.org/10.1038/ni.2342
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Brockman M; Chopera DR; Olvera A; Brumme C; Sela J; Markle TJ; Martin EPG; Carlson JM; Le AQ; Mcgovern R; Cheung PK; Kelleher AD; Jessen H; Markowitz M; Rosenberg E; Frahm N; Sanchez J; Mallal S; John M; Harrigan PR; Heckerman D; Brander C; Walker BD; Brummea ZL, 2012, 'Uncommon pathways of immune escape attenuate HIV-1 integrase replication capacity', Journal of Virology, vol. 86, pp. 6913 - 6923, http://dx.doi.org/10.1128/JVI.07133-11
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Ranasinghe S; Flanders M; Cutler S; Soghoian DZ; Ghebremichael M; Davis I; Lindqvist M; Pereyra F; Walker BD; Heckerman D; Streeck H, 2012, 'HIV-specific CD4 T cell responses to different viral proteins have discordant associations with viral load and clinical outcome.', J Virol, vol. 86, pp. 277 - 283, http://dx.doi.org/10.1128/JVI.05577-11
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Mothe B; Llano A; Ibarrondo J; Zamarreño J; Schiaulini M; Miranda C; Ruiz-Riol M; Berger CT; Herrero MJ; Palou E; Plana M; Rolland M; Khatri A; Heckerman D; Pereyra F; Walker BD; Weiner D; Paredes R; Clotet B; Felber BK; Pavlakis GN; Mullins JI; Brander C, 2012, 'CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control.', PLoS One, vol. 7, pp. e29717, http://dx.doi.org/10.1371/journal.pone.0029717
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Zhu J; Gaiha GD; John SP; Pertel T; Chin CR; Gao G; Qu H; Walker BD; Elledge SJ; Brass AL, 2012, 'Reactivation of latent HIV-1 by inhibition of BRD4.', Cell Rep, vol. 2, pp. 807 - 816, http://dx.doi.org/10.1016/j.celrep.2012.09.008
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Thobakgale CF; Fadda L; Lane K; Toth I; Pereyra F; Bazner S; Ndung'u T; Walker BD; Rosenberg ES; Alter G; Carrington M; Allen TM; Altfeld M, 2012, 'Frequent and strong antibody-mediated natural killer cell activation in response to HIV-1 Env in individuals with chronic HIV-1 infection.', J Virol, vol. 86, pp. 6986 - 6993, http://dx.doi.org/10.1128/JVI.00569-12
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Chopera DR; Cotton LA; Zawaira A; Mann JK; Ngandu NK; Ntale R; Carlson JM; Mlisana K; Woodman Z; de Assis Rosa D; Martin E; Miura T; Pereyra F; Walker BD; Gray CM; Martin DP; Ndung'u T; Brockman MA; Karim SA; Brumme ZL; Williamson C; CAPRISA 002 Study Team , 2012, 'Intersubtype differences in the effect of a rare p24 gag mutation on HIV-1 replicative fitness.', J Virol, vol. 86, pp. 13423 - 13433, http://dx.doi.org/10.1128/JVI.02171-12
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Carlson JM; Listgarten J; Pfeifer N; Tan V; Kadie C; Walker BD; Ndung'u T; Shapiro R; Frater J; Brumme ZL; Goulder PJR; Heckerman D, 2012, 'Widespread impact of HLA restriction on immune control and escape pathways of HIV-1.', J Virol, vol. 86, pp. 5230 - 5243, http://dx.doi.org/10.1128/JVI.06728-11
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Klein F; Gaebler C; Mouquet H; Sather DN; Lehmann C; Scheid JF; Kraft Z; Liu Y; Pietzsch J; Hurley A; Poignard P; Feizi T; Morris L; Walker BD; Fätkenheuer G; Seaman MS; Stamatatos L; Nussenzweig MC, 2012, 'Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein.', J Exp Med, vol. 209, pp. 1469 - 1479, http://dx.doi.org/10.1084/jem.20120423
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Stephenson KE; Li H; Walker BD; Michael NL; Barouch DH, 2012, 'Gag-specific cellular immunity determines in vitro viral inhibition and in vivo virologic control following simian immunodeficiency virus challenges of vaccinated rhesus monkeys.', J Virol, vol. 86, pp. 9583 - 9589, http://dx.doi.org/10.1128/JVI.00996-12
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Ndhlovu ZM; Proudfoot J; Cesa K; Alvino DM; McMullen A; Vine S; Stampouloglou E; Piechocka-Trocha A; Walker BD; Pereyra F, 2012, 'Elite controllers with low to absent effector CD8+ T cell responses maintain highly functional, broadly directed central memory responses.', J Virol, vol. 86, pp. 6959 - 6969, http://dx.doi.org/10.1128/JVI.00531-12
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Soghoian DZ; Jessen H; Flanders M; Sierra-Davidson K; Cutler S; Pertel T; Ranasinghe S; Lindqvist M; Davis I; Lane K; Rychert J; Rosenberg ES; Piechocka-Trocha A; Brass AL; Brenchley JM; Walker BD; Streeck H, 2012, 'HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome.', Sci Transl Med, vol. 4, pp. 123ra25, http://dx.doi.org/10.1126/scitranslmed.3003165
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Zhang SC; Martin E; Shimada M; Godfrey SB; Fricke J; Locastro S; Lai NY; Liebesny P; Carlson JM; Brumme CJ; Ogbechie OA; Chen H; Walker BD; Brumme ZL; Kavanagh DG; Le Gall S, 2012, 'Aminopeptidase substrate preference affects HIV epitope presentation and predicts immune escape patterns in HIV-infected individuals.', J Immunol, vol. 188, pp. 5924 - 5934, http://dx.doi.org/10.4049/jimmunol.1200219
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Martin DO; Lemke B; Birnie D; Krum H; Lee KLF; Aonuma K; Gasparini M; Starling RC; Milasinovic G; Rogers T; Sambelashvili A; Gorcsan J; Houmsse M; Wells P; Merliss A; Khan I; Stone J; Rodak D; Lee S; Milstein S; Svinarich T; Lustgarten D; Sorrentino R; McKenzie J; Hobson J; Allison JS; Van De Bruyn ; Lessmeier T; Johnson W; Goel S; Emert M; Lerman R; Chaudhry M; Klein S; Imburgia M; Gold M; Zaman L; Ramza B; Bailey J; Bello D; Foreman B; Kawasaki R; Lobban J; Curwin J; Turitto G; Lowy J; Karanam S; Putz E; Collier J; Simonson J; Mikaelian B; Compton S; Pires L; Walsh J; Wadhwa M; Herre J; Canby R; Bruce K; Sims J; Carney R; Bank A; Borganelli M; Clair W; Shepard R; Cheung J; Elmouchi D; Heath F; Kypta A; Mortensen PT; Voss F; Lawo T; Bouwels LH; Landolina ME; Faerestrand S; Gil M; Kovacevic DV; Hörnsten J; Perisic Z; Nägele H; Scheffer M; Brandes A; Kongsgård E; Hassager C; Hersi A; Kuznetsov VA; Aydin MA; Borgquist R; Mullens W; Paul V; Kilborn M; Hayes J; Walker B; Denman R; Sanders P; Yee R; Khaykin Y; Sumner G; Tang A; Kamakura S; Tse HF, 2012, 'Investigation of a novel algorithm for synchronized left-ventricular pacing and ambulatory optimization of cardiac resynchronization therapy: Results of the adaptive CRT trial', Heart Rhythm, vol. 9, http://dx.doi.org/10.1016/j.hrthm.2012.07.009
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Shekhar K; Dahirel V; Walker BD; Chakraborty AK, 2012, 'Analysis of Collective Coevolution in HIV Proteins Suggests Strategies for Rational Vaccine Design', Biophysical Journal, vol. 102, pp. 22a - 23a, http://dx.doi.org/10.1016/j.bpj.2011.11.149
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Gaiha G; Anahtar M; Rossin E; Walker B, 2012, 'Determination of structural constraint within the HIV proteome through analysis of amino acid microenvironments', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p349
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Stephenson KE; Li H; Walker BD; Michael NL; Barouch DH, 2012, 'Gag-specific cellular immunity determines in vitro viral inhibition and in vivo virologic control following SIV challenges of vaccinated monkeys', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p245
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Angin M; King M; Altfeld M; Walker BD; Wucherpfennig KW; Addo MM, 2012, 'Identification of HIV-1-specific regulatory T-cells using HLA class II tetramers.', AIDS, vol. 26, pp. 2112 - 2115, http://dx.doi.org/10.1097/QAD.0b013e328358cc75
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Radebe M; Ndhlovu Z; Mokgoro M; Maphumulo L; Jaggernath M; Chonco F; Ndung'u T; Walker BD, 2012, 'Longitudinal assessment of HIV-1-specific T-cell responses generated during acute subtype C HIV-1 infection and associations with viral set point', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p272
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Cotton L; Chopera D; Penney K; Carlson J; Martin E; Le A; Kuang T; Walker B; Fuchs J; Buchbinder S; Wagner T; John M; Mallal S; Koblin B; Mayer K; Poon A; Brockman M; Brumme Z, 2012, 'Limited evidence for alterations in Gag-mediated HIV replication capacity over the course of the North American epidemic (1979-present)', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p157
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Li JZ; Brumme CJ; Lederman MM; Brumme ZL; Wang H; Spritzler J; Carrington M; Medvik K; Walker BD; Schooley RT; Kuritzkes DR; AIDS Clinical Trials Group A5197 Study Team , 2012, 'Characteristics and outcomes of initial virologic suppressors during analytic treatment interruption in a therapeutic HIV-1 gag vaccine trial.', PLoS One, vol. 7, pp. e34134, http://dx.doi.org/10.1371/journal.pone.0034134
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Gounder K; Leshwedi M; Wright J; van der Stok M; Chonco F; Padayachee N; Ndimande B; Mokgoro M; Jaggernath M; Goulder P; Walker BD, 2012, 'Immunodominance and viral ditness in Gag may contribute to differential viral control in HLA-B*7 supertype individuals acutely infected with HIV-1C', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p160
    Journal articles | 2012
    Dr Bruce Duncan Walker
    McElrath MJ; Walker BD, 2012, 'Is an HIV vaccine possible?', J Acquir Immune Defic Syndr, vol. 60 Suppl 2, pp. S41 - S43, http://dx.doi.org/10.1097/QAI.0b013e31825b7118
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Kløverpris H; Jackson A; Handley A; Hayes P; Gilmour J; Atkins M; Walker B; Ackland J; Sullivan M; Goulder P, 2012, 'Immune response after vaccination of HIV infected individuals receiving HAART with overlapping gag peptides pulsed on autologous cells', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p115
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Jost S; Moreno-Nieves UY; Garcia Beltran WF; Rands K; Reardon J; Toth I; Piechocka-Trocha A; Walker BD; Altfeld M; Addo MM, 2012, 'Tim-3-mediated signaling in NK cells may be modulated by increased Galectin-9 expression in HIV-1 infection', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p173
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Thobakgale CF; Carlson J; Wright J; van Teijlingen N; Jaggernath M; Goulder P; Walker BD; Carrington M; Heckerman D; Altfeld M; Ndung'u T, 2012, 'KIR-HLA footprints and NK cell-mediated recognition of HIV-1', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p170
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Thobakgale C; Fadda L; Lane K; Toth I; Pereyra F; Bazner S; Ndung'u T; Walker BD; Rosenberg E; Alter G; Carrington M; Allen T; Altfeld M, 2012, 'Frequent and strong antibody-mediated NK cell activation to HIV-1 Env in individuals with chronic HIV-1 infection', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p171
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Naicker D; Julg B; McClurg C; Ghebremichael M; Porichis F; Zupkosky J; Jaggernath M; Mokgoro M; Goulder P; Walker B; Kaufmann D; Ndung'u T, 2012, 'Association of interleukin-10 promoter genetic variants with T-cell and B-cell activation in HIV-1 infection', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p168
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Ndhlovu ZM; Chibnik LB; Proudfoot J; Vine S; McMullen A; Cesa K; Alvino DM; Piechocka-Trocha A; de Jager PL; Kaufmann DE; Walker BD, 2012, 'A high dimensional immune monitoring model of HIV-specific CD8 T cell responses accurately identifies subjects achieving spontaneous control of viral replication', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s1-p19
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Shasha D; Porichis F; Daniel K; Angiuli O; Kaufmann DE; Walker B, 2012, 'Comparable antiviral capacity but favorable in vitro survival of CD8s from elite controllers compared to untreated progressors', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p286
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Vaidya SA; Streeck H; Pereyra F; Rosenberg ES; Walker BD; Altfeld M, 2012, 'The viral set point in primary HIV infection is associated with specific amino acids in position 97 of MHC class I', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p163
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Kløverpris H; Harndahl M; Carlson J; Leslie A; van der Stok M; Huang G; Chen F; Riddell L; Steyn D; Goedhals D; van Vuuren C; Frater J; Walker B; Ndung'u' T; Buus S; Goulder P, 2012, 'HIV control through a single nucleotide on the HLA-I locus', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-o47
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Mitchell JE; Chetty S; Govender P; Pillay M; Jaggernath M; Kasmar A; Ndung'u T; Klenerman P; Walker BD; Kasprowicz VO, 2012, 'Prospective monitoring reveals dynamic levels of T cell immunity to Mycobacterium tuberculosis in HIV infected individuals.', PLoS One, vol. 7, pp. e37920, http://dx.doi.org/10.1371/journal.pone.0037920
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Ndhlovu ZM; Chibnik L; Proudfoot J; Vine S; McMullen A; Cesa K; Porichis F; Alvino D; Piechocka-Trocha A; De Jager P; Walker BD; Kaufmann D, 2012, 'A high-dimensional immune monitoring model of HIV-1-specific CD8 T cell responses accurately identifies subjects achieving spontaneous viral control', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p280
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Holt NG; Johnson J; Wilton S; Byrne E; Piechocka-Trocha A; Walker BD; Kwon D, 2012, 'γδ T-cells in HIV infection', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p200
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Soghoian DZ; Flanders M; Sierra-Davidson K; Ranasinghe S; Cutler S; Davis I; Lindqvist M; Lane K; Kuhl B; Kranias G; Piechocka-Trocha A; Jessen H; Walker BD; Streeck H, 2012, 'HIV-specific cytolytic CD4 T-cell responses effectively control HIV infection in macrophages', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p274
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Angin M; Streeck H; Wen F; King M; Pereyra F; Altfeld M; Walker BD; Addo MM, 2012, 'Regulatory T cell frequencies do not correlate with breadth or magnitude of HIV-1-specific T cell responses.', AIDS Res Hum Retroviruses, vol. 28, pp. 749 - 751, http://dx.doi.org/10.1089/AID.2011.0353
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Chen H; Ndhlovu ZM; Liu D; Porter LC; Fang JW; Darko S; Brockman MA; Miura T; Brumme ZL; Schneidewind A; Piechocka-Trocha A; Cesa KT; Sela J; Cung TD; Toth I; Pereyra F; Yu XG; Douek DC; Kaufmann DE; Allen TM; Walker BD, 2012, 'T cell receptor clonotypes modulate the protective effect of human leukocyte antigen class I alleles in HIV-1 infection', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-p264
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Walker BD, 2012, 'Secrets of the HIV controllers: A rare group of HIV-positive individuals need no medicine to keep the virus in check. Their good fortune could point the way to more powerful treatments--and perhaps a vaccine.', Sci Am, vol. 307, pp. 44 - 51, https://www.ncbi.nlm.nih.gov/pubmed/22779271
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Lemon T; Alvino D; Ndhlovu Z; Walker B, 2012, 'Role of functional avidity in HIV-specific memory CD8 T cell effector functions', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s1-p26
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Chetty S; Porichis F; Govender P; Zupkosky J; Pillay M; Walker B; Ndung’u T; Kaufmann D; Kasprowicz V, 2012, 'Co-infection with Mycobacterium tuberculosis impairs HIV-specific CD8+ and CD4+ T cell functionality', International Journal of Infectious Diseases, vol. 16, pp. e23 - e23, http://dx.doi.org/10.1016/j.ijid.2012.05.061
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Jackson AG; Kløverpris HN; Handley A; Hayes P; Gilmour J; Atkins M; Walker B; Ackland J; Sullivan M; Goulder P, 2012, 'A first-in-man, double blind, placebo controlled study of the candidate therapeutic vaccine Opal-HIV-Gag(c) in HIV infected patients receiving HAART', Retrovirology, vol. 9, http://dx.doi.org/10.1186/1742-4690-9-s2-o54
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Chia PL; Subbiah RN; Kuchar D; Walker B, 2012, 'Unusual adverse consequence of reverse ventricular remodelling following cardiac resynchronization therapy', Europace, vol. 14, pp. 1216 - 1217, http://dx.doi.org/10.1093/europace/eur422
    Journal articles | 2012
    Dr Bruce Duncan Walker
    Kikuchi T; Iwabu Y; Kawana-Tachikawa A; Koga M; Hosoya N; Nomura S; Brumme ZL; Jessen H; Kelleher A; Markowitz M; Pereyra F; Trocha A; Walker BD; Iwamoto A; Tokunaga K; Miura T, 2012, 'Anti-APOBEC3G activity of HIV-1 Vif protein from elite controllers is attenuated compared to those from untreated chronic progressors or those from individuals with acute infection', JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, vol. 15, pp. 19 - 19, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310588200043&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Novitsky V; Ndung'u T; Wang R; Bussmann H; Chonco F; Makhema J; De Gruttola V; Walker BD; Essex M, 2011, 'Extended high viremics: a substantial fraction of individuals maintain high plasma viral RNA levels after acute HIV-1 subtype C infection.', AIDS, vol. 25, pp. 1515 - 1522, http://dx.doi.org/10.1097/QAD.0b013e3283471eb2
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Walker BD; Ahmed R; Plotkin S, 2011, 'Moving ahead an HIV vaccine: use both arms to beat HIV.', Nat Med, vol. 17, pp. 1194 - 1195, http://dx.doi.org/10.1038/nm.2529
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Buranapraditkun S; Hempel U; Pitakpolrat P; Allgaier RL; Thantivorasit P; Lorenzen S-I; Sirivichayakul S; Hildebrand WH; Altfeld M; Brander C; Walker BD; Phanuphak P; Hansasuta P; Rowland-Jones SL; Allen TM; Ruxrungtham K, 2011, 'A novel immunodominant CD8+ T cell response restricted by a common HLA-C allele targets a conserved region of Gag HIV-1 clade CRF01_AE infected Thais.', PLoS One, vol. 6, pp. e23603, http://dx.doi.org/10.1371/journal.pone.0023603
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Rodríguez-García M; Porichis F; de Jong OG; Levi K; Diefenbach TJ; Lifson JD; Freeman GJ; Walker BD; Kaufmann DE; Kavanagh DG, 2011, 'Expression of PD-L1 and PD-L2 on human macrophages is up-regulated by HIV-1 and differentially modulated by IL-10.', J Leukoc Biol, vol. 89, pp. 507 - 515, http://dx.doi.org/10.1189/jlb.0610327
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Hersperger AR; Martin JN; Shin LY; Sheth PM; Kovacs CM; Cosma GL; Makedonas G; Pereyra F; Walker BD; Kaul R; Deeks SG; Betts MR, 2011, 'Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression.', Blood, vol. 117, pp. 3799 - 3808, http://dx.doi.org/10.1182/blood-2010-12-322727
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Mothe B; Llano A; Ibarrondo J; Daniels M; Miranda C; Zamarreño J; Bach V; Zuniga R; Pérez-Álvarez S; Berger CT; Puertas MC; Martinez-Picado J; Rolland M; Farfan M; Szinger JJ; Hildebrand WH; Yang OO; Sanchez-Merino V; Brumme CJ; Brumme ZL; Heckerman D; Allen TM; Mullins JI; Gómez G; Goulder PJ; Walker BD; Gatell JM; Clotet B; Korber BT; Sanchez J; Brander C, 2011, 'Definition of the viral targets of protective HIV-1-specific T cell responses.', J Transl Med, vol. 9, pp. 208, http://dx.doi.org/10.1186/1479-5876-9-208
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Addo MM; Altfeld M; Brainard DM; Rathod A; Piechocka-Trocha A; Fideli U; Mulenga J; Shutes E; Alvino DML; Hunter E; Allen SA; Walker BD, 2011, 'Lack of detectable HIV-1-specific CD8(+) T cell responses in Zambian HIV-1-exposed seronegative partners of HIV-1-positive individuals.', J Infect Dis, vol. 203, pp. 258 - 262, http://dx.doi.org/10.1093/infdis/jiq028
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Chen H; Li C; Huang J; Cung T; Seiss K; Beamon J; Carrington MF; Porter LC; Burke PS; Yang Y; Ryan BJ; Liu R; Weiss RH; Pereyra F; Cress WD; Brass AL; Rosenberg ES; Walker BD; Yu XG; Lichterfeld M, 2011, 'CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21.', J Clin Invest, vol. 121, pp. 1549 - 1560, http://dx.doi.org/10.1172/JCI44539
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Dahirel V; Shekhar K; Pereyra F; Miura T; Artyomov M; Talsania S; Allen TM; Altfeld M; Carrington M; Irvine DJ; Walker BD; Chakraborty AK, 2011, 'Coordinate linkage of HIV evolution reveals regions of immunological vulnerability.', Proc Natl Acad Sci U S A, vol. 108, pp. 11530 - 11535, http://dx.doi.org/10.1073/pnas.1105315108
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Li JZ; Brumme ZL; Brumme CJ; Wang H; Spritzler J; Robertson MN; Lederman MM; Carrington M; Walker BD; Schooley RT; Kuritzkes DR; AIDS Clinical Trials Group A5197 Study Team , 2011, 'Factors associated with viral rebound in HIV-1-infected individuals enrolled in a therapeutic HIV-1 gag vaccine trial.', J Infect Dis, vol. 203, pp. 976 - 983, http://dx.doi.org/10.1093/infdis/jiq143
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Chevalier MF; Jülg B; Pyo A; Flanders M; Ranasinghe S; Soghoian DZ; Kwon DS; Rychert J; Lian J; Muller MI; Cutler S; McAndrew E; Jessen H; Pereyra F; Rosenberg ES; Altfeld M; Walker BD; Streeck H, 2011, 'HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function.', J Virol, vol. 85, pp. 733 - 741, http://dx.doi.org/10.1128/JVI.02030-10
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Kim AY; Kuntzen T; Timm J; Nolan BE; Baca MA; Reyor LL; Berical AC; Feller AJ; Johnson KL; Schulze zur Wiesch J; Robbins GK; Chung RT; Walker BD; Carrington M; Allen TM; Lauer GM, 2011, 'Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes.', Gastroenterology, vol. 140, pp. 686 - 696.e1, http://dx.doi.org/10.1053/j.gastro.2010.09.042
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Kulkarni S; Savan R; Qi Y; Gao X; Yuki Y; Bass SE; Martin MP; Hunt P; Deeks SG; Telenti A; Pereyra F; Goldstein D; Wolinsky S; Walker B; Young HA; Carrington M, 2011, 'Differential microRNA regulation of HLA-C expression and its association with HIV control.', Nature, vol. 472, pp. 495 - 498, http://dx.doi.org/10.1038/nature09914
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Kasprowicz VO; Mitchell JE; Chetty S; Govender P; Huang K-HG; Fletcher HA; Webster DP; Brown S; Kasmar A; Millington K; Day CL; Mkhwanazi N; McClurg C; Chonco F; Lalvani A; Walker BD; Ndung'u T; Klenerman P, 2011, 'A molecular assay for sensitive detection of pathogen-specific T-cells.', PLoS One, vol. 6, pp. e20606, http://dx.doi.org/10.1371/journal.pone.0020606
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Singh R; Gaiha G; Werner L; McKim K; Mlisana K; Luban J; Walker BD; Karim SSA; Brass AL; Ndung'u T; CAPRISA Acute Infection Study Team , 2011, 'Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection.', J Virol, vol. 85, pp. 208 - 216, http://dx.doi.org/10.1128/JVI.01810-10
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Brumme ZL; Li C; Miura T; Sela J; Rosato PC; Brumme CJ; Markle TJ; Martin E; Block BL; Trocha A; Kadie CM; Allen TM; Pereyra F; Heckerman D; Walker BD; Brockman MA, 2011, 'Reduced replication capacity of NL4-3 recombinant viruses encoding reverse transcriptase-integrase sequences from HIV-1 elite controllers.', J Acquir Immune Defic Syndr, vol. 56, pp. 100 - 108, http://dx.doi.org/10.1097/QAI.0b013e3181fe9450
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Scheid JF; Mouquet H; Ueberheide B; Diskin R; Klein F; Oliveira TYK; Pietzsch J; Fenyo D; Abadir A; Velinzon K; Hurley A; Myung S; Boulad F; Poignard P; Burton DR; Pereyra F; Ho DD; Walker BD; Seaman MS; Bjorkman PJ; Chait BT; Nussenzweig MC, 2011, 'Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding.', Science, vol. 333, pp. 1633 - 1637, http://dx.doi.org/10.1126/science.1207227
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Thobakgale CF; Streeck H; Mkhwanazi N; Mncube Z; Maphumulo L; Chonco F; Prendergast A; Tudor-Williams G; Walker BD; Goulder PJR; Altfeld M; Ndung'u T, 2011, 'Short communication: CD8(+) T cell polyfunctionality profiles in progressive and nonprogressive pediatric HIV type 1 infection.', AIDS Res Hum Retroviruses, vol. 27, pp. 1005 - 1012, http://dx.doi.org/10.1089/AID.2010.0227
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Wright JK; Novitsky V; Brockman MA; Brumme ZL; Brumme CJ; Carlson JM; Heckerman D; Wang B; Losina E; Leshwedi M; van der Stok M; Maphumulo L; Mkhwanazi N; Chonco F; Goulder PJR; Essex M; Walker BD; Ndung'u T, 2011, 'Influence of Gag-protease-mediated replication capacity on disease progression in individuals recently infected with HIV-1 subtype C.', J Virol, vol. 85, pp. 3996 - 4006, http://dx.doi.org/10.1128/JVI.02520-10
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Julg B; Moodley ES; Qi Y; Ramduth D; Reddy S; Mncube Z; Gao X; Goulder PJ; Detels R; Ndung'u T; Walker BD; Carrington M, 2011, 'Possession of HLA class II DRB1*1303 associates with reduced viral loads in chronic HIV-1 clade C and B infection.', J Infect Dis, vol. 203, pp. 803 - 809, http://dx.doi.org/10.1093/infdis/jiq122
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Radebe M; Nair K; Chonco F; Bishop K; Wright JK; van der Stok M; Bassett IV; Mncube Z; Altfeld M; Walker BD; Ndung'u T, 2011, 'Limited immunogenicity of HIV CD8+ T-cell epitopes in acute Clade C virus infection.', J Infect Dis, vol. 204, pp. 768 - 776, http://dx.doi.org/10.1093/infdis/jir394
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Streeck H; Kwon DS; Pyo A; Flanders M; Chevalier MF; Law K; Jülg B; Trocha K; Jolin JS; Anahtar MN; Lian J; Toth I; Brumme Z; Chang JJ; Caron T; Rodig SJ; Milner DA; Piechoka-Trocha A; Kaufmann DE; Walker BD; Altfeld M, 2011, 'Epithelial adhesion molecules can inhibit HIV-1-specific CD8⁺ T-cell functions.', Blood, vol. 117, pp. 5112 - 5122, http://dx.doi.org/10.1182/blood-2010-12-321588
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Ndhlovu ZM; Piechocka-Trocha A; Vine S; McMullen A; Koofhethile KC; Goulder PJR; Ndung'u T; Barouch DH; Walker BD, 2011, 'Mosaic HIV-1 Gag antigens can be processed and presented to human HIV-specific CD8+ T cells.', J Immunol, vol. 186, pp. 6914 - 6924, http://dx.doi.org/10.4049/jimmunol.1004231
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Kasprowicz V; zur Wiesch JS; Kuntzen T; Nolan BE; Longworth S; Berical A; Blum J; McMahon C; Reyor LL; Elias N; Kwok WW; McGovern BG; Freeman G; Chung RT; Klenerman P; Lewis-Ximenez L; Walker BD; Allen TM; Kim AY; Lauer GM, 2011, 'High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8+ and CD4+ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome', Journal of Virology, vol. 85, pp. 4633 - 4633, http://dx.doi.org/10.1128/jvi.00376-11
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Mwimanzi P; Markle T; Otsuka H; Ogata Y; Tokunaga M; Miura T; Martin E; Pereyra F; Walker B; Brumme Z; Brockman M; Ueno T, 2011, 'Impairment of viral replication capacity by nef alleles from HIV elite controllers', Retrovirology, vol. 8, http://dx.doi.org/10.1186/1742-4690-8-s2-p53
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Kasprowicz V; Ward SM; Turner A; Grammatikos A; Nolan BE; Lewis-Ximenez L; Sharp C; Woodruff J; Fleming VM; Sims S; Walker BD; Sewell AK; Lauer GM; Klenerman P, 2011, 'Defining the directionality and quality of influenza virus–specific CD8+ T cell cross-reactivity in individuals infected with hepatitis C virus', Journal of Clinical Investigation, vol. 121, pp. 1223 - 1223, http://dx.doi.org/10.1172/jci57501
    Journal articles | 2011
    Dr Bruce Duncan Walker
    Matthews PC; Leslie AJ; Katzourakis A; Crawford H; Payne R; Prendergast A; Power K; Kelleher AD; Klenerman P; Carlson J; Heckerman D; Ndung'u T; Walker BD; Allen TM; Pybus OG; Goulder PJR, 2011, 'HLA footprints on human immunodeficiency virus type 1 are associated with interclade polymorphisms and intraclade phylogenetic clustering', Journal of Virology, vol. 85, pp. 4635, http://dx.doi.org/10.1128/JVI.00375-11
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Virgin HW; Walker BD, 2010, 'Immunology and the elusive AIDS vaccine.', Nature, vol. 464, pp. 224 - 231, http://dx.doi.org/10.1038/nature08898
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Quigley M; Pereyra F; Nilsson B; Porichis F; Fonseca C; Eichbaum Q; Julg B; Jesneck JL; Brosnahan K; Imam S; Russell K; Toth I; Piechocka-Trocha A; Dolfi D; Angelosanto J; Crawford A; Shin H; Kwon DS; Zupkosky J; Francisco L; Freeman GJ; Wherry EJ; Kaufmann DE; Walker BD; Ebert B; Haining WN, 2010, 'Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF.', Nat Med, vol. 16, pp. 1147 - 1151, http://dx.doi.org/10.1038/nm.2232
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Wright JK; Brumme ZL; Carlson JM; Heckerman D; Kadie CM; Brumme CJ; Wang B; Losina E; Miura T; Chonco F; van der Stok M; Mncube Z; Bishop K; Goulder PJR; Walker BD; Brockman MA; Ndung'u T, 2010, 'Gag-protease-mediated replication capacity in HIV-1 subtype C chronic infection: associations with HLA type and clinical parameters.', J Virol, vol. 84, pp. 10820 - 10831, http://dx.doi.org/10.1128/JVI.01084-10
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Huang J; Burke PS; Cung TDH; Pereyra F; Toth I; Walker BD; Borges L; Lichterfeld M; Yu XG, 2010, 'Leukocyte immunoglobulin-like receptors maintain unique antigen-presenting properties of circulating myeloid dendritic cells in HIV-1-infected elite controllers.', J Virol, vol. 84, pp. 9463 - 9471, http://dx.doi.org/10.1128/JVI.01009-10
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Wong AHW; Williams K; Reddy S; Wilson D; Giddy J; Alter G; Ghebremichael M; Carrington MN; Ndung'u T; Walker BD; Altfeld M; Carr WH, 2010, 'Alterations in natural killer cell receptor profiles during HIV type 1 disease progression among chronically infected South African adults.', AIDS Res Hum Retroviruses, vol. 26, pp. 459 - 469, http://dx.doi.org/10.1089/aid.2009.0176
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Honeyborne I; Codoñer FM; Leslie A; Tudor-Williams G; Luzzi G; Ndung'u T; Walker BD; Goulder PJ; Prado JG, 2010, 'HLA-Cw*03-restricted CD8+ T-cell responses targeting the HIV-1 gag major homology region drive virus immune escape and fitness constraints compensated for by intracodon variation.', J Virol, vol. 84, pp. 11279 - 11288, http://dx.doi.org/10.1128/JVI.01144-10
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Hersperger AR; Pereyra F; Nason M; Demers K; Sheth P; Shin LY; Kovacs CM; Rodriguez B; Sieg SF; Teixeira-Johnson L; Gudonis D; Goepfert PA; Lederman MM; Frank I; Makedonas G; Kaul R; Walker BD; Betts MR, 2010, 'Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control.', PLoS Pathog, vol. 6, pp. e1000917, http://dx.doi.org/10.1371/journal.ppat.1000917
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Rolland M; Carlson JM; Manocheewa S; Swain JV; Lanxon-Cookson E; Deng W; Rousseau CM; Raugi DN; Learn GH; Maust BS; Coovadia H; Ndung'u T; Goulder PJR; Walker BD; Brander C; Heckerman DE; Mullins JI, 2010, 'Amino-acid co-variation in HIV-1 Gag subtype C: HLA-mediated selection pressure and compensatory dynamics.', PLoS One, vol. 5, http://dx.doi.org/10.1371/journal.pone.0012463
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Bansal A; Carlson J; Yan J; Akinsiku OT; Schaefer M; Sabbaj S; Bet A; Levy DN; Heath S; Tang J; Kaslow RA; Walker BD; Ndung'u T; Goulder PJ; Heckerman D; Hunter E; Goepfert PA, 2010, 'CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription.', J Exp Med, vol. 207, pp. 51 - 59, http://dx.doi.org/10.1084/jem.20092060
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Kosmrlj A; Read EL; Qi Y; Allen TM; Altfeld M; Deeks SG; Pereyra F; Carrington M; Walker BD; Chakraborty AK, 2010, 'Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection.', Nature, vol. 465, pp. 350 - 354, http://dx.doi.org/10.1038/nature08997
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Spentzou A; Bergin P; Gill D; Cheeseman H; Ashraf A; Kaltsidis H; Cashin-Cox M; Anjarwalla I; Steel A; Higgs C; Pozniak A; Piechocka-Trocha A; Wong J; Anzala O; Karita E; Dally L; Gotch F; Walker B; Gilmour J; Hayes P, 2010, 'Viral inhibition assay: a CD8 T cell neutralization assay for use in clinical trials of HIV-1 vaccine candidates.', J Infect Dis, vol. 201, pp. 720 - 729, http://dx.doi.org/10.1086/650492
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Leslie A; Matthews PC; Listgarten J; Carlson JM; Kadie C; Ndung'u T; Brander C; Coovadia H; Walker BD; Heckerman D; Goulder PJR, 2010, 'Additive contribution of HLA class I alleles in the immune control of HIV-1 infection.', J Virol, vol. 84, pp. 9879 - 9888, http://dx.doi.org/10.1128/JVI.00320-10
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Julg B; Williams KL; Reddy S; Bishop K; Qi Y; Carrington M; Goulder PJ; Ndung'u T; Walker BD, 2010, 'Enhanced anti-HIV functional activity associated with Gag-specific CD8 T-cell responses.', J Virol, vol. 84, pp. 5540 - 5549, http://dx.doi.org/10.1128/JVI.02031-09
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Mouquet H; Scheid JF; Zoller MJ; Krogsgaard M; Ott RG; Shukair S; Artyomov MN; Pietzsch J; Connors M; Pereyra F; Walker BD; Ho DD; Wilson PC; Seaman MS; Eisen HN; Chakraborty AK; Hope TJ; Ravetch JV; Wardemann H; Nussenzweig MC, 2010, 'Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation.', Nature, vol. 467, pp. 591 - 595, http://dx.doi.org/10.1038/nature09385
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Prado JG; Prendergast A; Thobakgale C; Molina C; Tudor-Williams G; Ndung'u T; Walker BD; Goulder P, 2010, 'Replicative capacity of human immunodeficiency virus type 1 transmitted from mother to child is associated with pediatric disease progression rate.', J Virol, vol. 84, pp. 492 - 502, http://dx.doi.org/10.1128/JVI.01743-09
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Banerjee K; Klasse PJ; Sanders RW; Pereyra F; Michael E; Lu M; Walker BD; Moore JP, 2010, 'IgG subclass profiles in infected HIV type 1 controllers and chronic progressors and in uninfected recipients of Env vaccines.', AIDS Res Hum Retroviruses, vol. 26, pp. 445 - 458, http://dx.doi.org/10.1089/aid.2009.0223
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Julg B; Pereyra F; Buzón MJ; Piechocka-Trocha A; Clark MJ; Baker BM; Lian J; Miura T; Martinez-Picado J; Addo MM; Walker BD, 2010, 'Infrequent recovery of HIV from but robust exogenous infection of activated CD4(+) T cells in HIV elite controllers.', Clin Infect Dis, vol. 51, pp. 233 - 238, http://dx.doi.org/10.1086/653677
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Williams K; Seiss K; Beamon J; Pereyra F; Rosenberg ES; Walker BD; Yu XG; Lichterfeld M, 2010, 'Epigenetic regulation of telomerase expression in HIV-1-specific CD8+ T cells.', AIDS, vol. 24, pp. 1964 - 1966, http://dx.doi.org/10.1097/QAD.0b013e32833c7170
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Henn MR; Lennon NJ; Newman R; Charlebois P; Boutwell C; OhAinle M; Berlin A; Ryan E; Malboeuf C; Macalalad A; Casali M; Erlich R; Bigelow H; Green L; Gnerre S; Young S; Levin J; Nusbaum C; Walker BD; Diamond MS; Kramer LD; Ebel GD; Harris E; Allen TM; Birren BW, 2010, 'Sensitive population profiling and genome assembly of HIV and Flaviviruses using ultra-deep sequencing technologies', Genome Biology, vol. 11, pp. P18 - P18, http://dx.doi.org/10.1186/gb-2010-11-s1-p18
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Phan J; Hayward C; Tay A; Subbiah R; Kuchar D; Thorburn C; Walker B, 2010, 'The CRT Learning Curve: A Single Centre Experience', Heart, Lung and Circulation, vol. 19, pp. S112 - S112, http://dx.doi.org/10.1016/j.hlc.2010.06.929
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Miura T; Brumme CJ; Brockman MA; Brumme ZL; Pereyra F; Block BL; Trocha A; John M; Mallal S; Harrigan PR; Walker BD, 2010, 'HLA-Associated Viral Mutations Are Common in Human Immunodeficiency Virus Type 1 Elite Controllers', Journal of Virology, vol. 84, pp. 1212 - 1212, http://dx.doi.org/10.1128/jvi.02204-09
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Mkhwanazi N; Thobakgale CF; van der Stok M; Reddy S; Mncube Z; Chonco F; Walker BD; Altfeld M; Goulder PJR; Ndung'u T, 2010, 'Immunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality.', Virology, vol. 405, pp. 483 - 491, http://dx.doi.org/10.1016/j.virol.2010.06.002
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Fricke J; Seung E; Vassor V; Tager AM; Gandhi RT; Walker B; Irvine D; Kavanagh D, 2010, 'Synthetic mRNA-loaded Nanoparticles Elicit Mucosal IL-17+ and IFNγ+ T Cells', Clinical Immunology, vol. 135, pp. S137 - S137, http://dx.doi.org/10.1016/j.clim.2010.03.416
    Journal articles | 2010
    Dr Bruce Duncan Walker
    Tay A; Walker B; Lim H; Subbiah R; Kuchar D; Thorburn C, 2010, 'Cardiac Device and Lead Displacement Secondary to Significant Weight Loss in the Obese Patient', Heart, Lung and Circulation, vol. 19, pp. S98 - S99, http://dx.doi.org/10.1016/j.hlc.2010.06.897
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Streeck H; Jolin J; Qi YC; Yassine-Diab B; Johnson ; Kwon D; Addo M; Brumme C; Routy J; Little S; Jessen H; Kelleher AD; Hecht FM; Sekaly R; Rosenberg E; Walker BD; Carrington M; Altfeld M, 2009, 'Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells', Journal of Virology, vol. 83, pp. 7641 - 7648, http://dx.doi.org/10.1128/JVI.00182-09
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Mahalanabis M; Jayaraman P; Miura T; Pereyra F; Chester EM; Richardson B; Walker B; Haigwood NL, 2009, 'Continuous viral escape and selection by autologous neutralizing antibodies in drug-naive human immunodeficiency virus controllers.', J Virol, vol. 83, pp. 662 - 672, http://dx.doi.org/10.1128/JVI.01328-08
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Apuzzo LG; Vaida F; Gallant JE; Ernstrom KB; Little SJ; Routy J-P; Collier AC; Conway B; Markowitz MH; Hecht FM; Walker BD; Connick E; Margolick JB, 2009, 'Tolerability and efficacy of PI versus NNRTI-based regimens in subjects receiving HAART during acute or early HIV infection.', J Acquir Immune Defic Syndr, vol. 50, pp. 267 - 275, http://dx.doi.org/10.1097/QAI.0b013e3181963ae6
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Brockman MA; Kwon DS; Tighe DP; Pavlik DF; Rosato PC; Sela J; Porichis F; Le Gall S; Waring MT; Moss K; Jessen H; Pereyra F; Kavanagh DG; Walker BD; Kaufmann DE, 2009, 'IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells.', Blood, vol. 114, pp. 346 - 356, http://dx.doi.org/10.1182/blood-2008-12-191296
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Miura T; Brockman MA; Brumme ZL; Brumme CJ; Pereyra F; Trocha A; Block BL; Schneidewind A; Allen TM; Heckerman D; Walker BD, 2009, 'HLA-associated alterations in replication capacity of chimeric NL4-3 viruses carrying gag-protease from elite controllers of human immunodeficiency virus type 1.', J Virol, vol. 83, pp. 140 - 149, http://dx.doi.org/10.1128/JVI.01471-08
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Thobakgale CF; Prendergast A; Crawford H; Mkhwanazi N; Ramduth D; Reddy S; Molina C; Mncube Z; Leslie A; Prado J; Chonco F; Mphatshwe W; Tudor-Williams G; Jeena P; Blanckenberg N; Dong K; Kiepiela P; Coovadia H; Ndung'u T; Walker BD; Goulder PJR, 2009, 'Impact of HLA in mother and child on disease progression of pediatric human immunodeficiency virus type 1 infection.', J Virol, vol. 83, pp. 10234 - 10244, http://dx.doi.org/10.1128/JVI.00921-09
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Schneidewind A; Brumme Z; Brumme C; Power KA; Reyor L; O Sullivan K; Gladden A; Hempel U; Kuntzen T; Wang YE; Oniangue-Ndza C; Jessen H; Markowitz M; Rosenberg E; Sekaly R; Kelleher AD; Walker BD; Allen TM, 2009, 'Transmission and long-term stability of compensated CD8 escape mutations', Journal of Virology, vol. 83, pp. 3993 - 3997, http://dx.doi.org/10.1128/JVI.01108-08
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Walley NM; Julg B; Dickson SP; Fellay J; Ge D; Walker BD; Carrington M; Cohen MS; de Bakker PIW; Goldstein DB; Shianna KV; Haynes BF; Letvin NL; McMichael AJ; Michael NL; Weintrob AC, 2009, 'The Duffy antigen receptor for chemokines null promoter variant does not influence HIV-1 acquisition or disease progression.', Cell Host Microbe, vol. 5, pp. 408 - 410, http://dx.doi.org/10.1016/j.chom.2009.04.011
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Liu Q; Sun Y; Rihn S; Nolting A; Tsoukas PN; Jost S; Cohen K; Walker B; Alter G, 2009, 'Matrix metalloprotease inhibitors restore impaired NK cell-mediated antibody-dependent cellular cytotoxicity in human immunodeficiency virus type 1 infection.', J Virol, vol. 83, pp. 8705 - 8712, http://dx.doi.org/10.1128/JVI.02666-08
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Kaufmann DE; Walker BD, 2009, 'PD-1 and CTLA-4 inhibitory cosignaling pathways in HIV infection and the potential for therapeutic intervention.', J Immunol, vol. 182, pp. 5891 - 5897, http://dx.doi.org/10.4049/jimmunol.0803771
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Crawford H; Lumm W; Leslie A; Schaefer M; Boeras D; Prado JG; Tang J; Farmer P; Ndung'u T; Lakhi S; Gilmour J; Goepfert P; Walker BD; Kaslow R; Mulenga J; Allen S; Goulder PJR; Hunter E, 2009, 'Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients.', J Exp Med, vol. 206, pp. 909 - 921, http://dx.doi.org/10.1084/jem.20081984
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Chen H; Piechocka-Trocha A; Miura T; Brockman MA; Julg BD; Baker BM; Rothchild AC; Block BL; Schneidewind A; Koibuchi T; Pereyra F; Allen TM; Walker BD, 2009, 'Differential neutralization of human immunodeficiency virus (HIV) replication in autologous CD4 T cells by HIV-specific cytotoxic T lymphocytes.', J Virol, vol. 83, pp. 3138 - 3149, http://dx.doi.org/10.1128/JVI.02073-08
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Scheid JF; Mouquet H; Feldhahn N; Walker BD; Pereyra F; Cutrell E; Seaman MS; Mascola JR; Wyatt RT; Wardemann H; Nussenzweig MC, 2009, 'A method for identification of HIV gp140 binding memory B cells in human blood.', J Immunol Methods, vol. 343, pp. 65 - 67, http://dx.doi.org/10.1016/j.jim.2008.11.012
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Miura T; Brockman MA; Schneidewind A; Lobritz M; Pereyra F; Rathod A; Block BL; Brumme ZL; Brumme CJ; Baker B; Rothchild AC; Li B; Trocha A; Cutrell E; Frahm N; Brander C; Toth I; Arts EJ; Allen TM; Walker BD, 2009, 'HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognition.', J Virol, vol. 83, pp. 2743 - 2755, http://dx.doi.org/10.1128/JVI.02265-08
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Brumme ZL; John M; Carlson JM; Brumme CJ; Chan D; Brockman MA; Swenson LC; Tao I; Szeto S; Rosato P; Sela J; Kadie CM; Frahm N; Brander C; Haas DW; Riddler SA; Haubrich R; Walker BD; Harrigan PR; Heckerman D; Mallal S, 2009, 'HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins.', PLoS One, vol. 4, pp. e6687, http://dx.doi.org/10.1371/journal.pone.0006687
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Foo D; Walker BD; Kuchar D; Thorburn CW; Tay A; Hayward CS; Macdonald PS; Keogh AM; Kotlyar E; Spratt P; Jansz PC, 2009, 'Left ventricular mechanical assist devices and cardiac device interactions: an observational case series', Pace - Pacing and Clinical Electrophysiology, vol. 32, pp. 879 - 887, http://dx.doi.org/10.1111/j.1540-8159.2009.02403.x
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Scheid JF; Mouquet H; Feldhahn N; Seaman MS; Velinzon K; Pietzsch J; Ott RG; Anthony RM; Zebroski H; Hurley A; Phogat A; Chakrabarti B; Li Y; Connors M; Pereyra F; Walker BD; Wardemann H; Ho D; Wyatt RT; Mascola JR; Ravetch JV; Nussenzweig MC, 2009, 'Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals.', Nature, vol. 458, pp. 636 - 640, http://dx.doi.org/10.1038/nature07930
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Miura T; Brumme CJ; Brockman MA; Brumme ZL; Pereyra F; Block BL; Trocha A; John M; Mallal S; Harrigan PR; Walker BD, 2009, 'HLA-associated viral mutations are common in human immunodeficiency virus type 1 elite controllers.', J Virol, vol. 83, pp. 3407 - 3412, http://dx.doi.org/10.1128/JVI.02459-08
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Thomas R; Apps R; Qi Y; Gao X; Male V; O'hUigin C; O'Connor G; Ge D; Fellay J; Martin JN; Margolick J; Goedert JJ; Buchbinder S; Kirk GD; Martin MP; Telenti A; Deeks SG; Walker BD; Goldstein D; McVicar DW; Moffett A; Carrington M, 2009, 'HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C.', Nat Genet, vol. 41, pp. 1290 - 1294, http://dx.doi.org/10.1038/ng.486
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Wang YE; Li B; Carlson JM; Streeck H; Gladden AD; Goodman R; Schneidewind A; Power KA; Toth I; Frahm N; Alter G; Brander C; Carrington M; Walker BD; Altfeld M; Heckerman D; Allen TM, 2009, 'Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1.', J Virol, vol. 83, pp. 1845 - 1855, http://dx.doi.org/10.1128/JVI.01061-08
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Streeck H; Frahm N; Walker BD, 2009, 'The role of IFN-gamma Elispot assay in HIV vaccine research.', Nat Protoc, vol. 4, pp. 461 - 469, http://dx.doi.org/10.1038/nprot.2009.7
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Pereyra F; Palmer S; Miura T; Block BL; Wiegand A; Rothchild AC; Baker B; Rosenberg R; Cutrell E; Seaman MS; Coffin JM; Walker BD, 2009, 'Persistent low-level viremia in HIV-1 elite controllers and relationship to immunologic parameters.', J Infect Dis, vol. 200, pp. 984 - 990, http://dx.doi.org/10.1086/605446
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Brainard DM; Seung E; Frahm N; Cariappa A; Bailey CC; Hart WK; Shin H-S; Brooks SF; Knight HL; Eichbaum Q; Yang Y-G; Sykes M; Walker BD; Freeman GJ; Pillai S; Westmoreland SV; Brander C; Luster AD; Tager AM, 2009, 'Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice.', J Virol, vol. 83, pp. 7305 - 7321, http://dx.doi.org/10.1128/JVI.02207-08
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Baker BM; Block BL; Rothchild AC; Walker BD, 2009, 'Elite control of HIV infection: implications for vaccine design.', Expert Opin Biol Ther, vol. 9, pp. 55 - 69, http://dx.doi.org/10.1517/14712590802571928
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Brumme ZL; Walker BD, 2009, 'Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification.', J Exp Med, vol. 206, pp. 1215 - 1218, http://dx.doi.org/10.1084/jem.20091094
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Boutwell CL; Schneidewind A; Brumme Z; Brockman M; Streeck H; Brumme C; Dudek T; Kane K; Kemper M; Walker B; Altfeld M; Allen T, 2009, 'P09-19 LB. CTL escape mutations in gag epitopes restricted by protective HLA class I alleles cause substantial reductions in viral replication capacity', Retrovirology, vol. 6, http://dx.doi.org/10.1186/1742-4690-6-s3-p399
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Lubong Sabado R; Kavanagh DG; Kaufmann DE; Fru K; Babcock E; Rosenberg E; Walker B; Lifson J; Bhardwaj N; Larsson M, 2009, 'In vitro priming recapitulates in vivo HIV-1 specific T cell responses, revealing rapid loss of virus reactive CD4 T cells in acute HIV-1 infection.', PLoS One, vol. 4, pp. e4256, http://dx.doi.org/10.1371/journal.pone.0004256
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Julg B; Reddy S; van der Stok M; Kulkarni S; Qi Y; Bass S; Gold B; Nalls MA; Nelson GW; Walker BD; Carrington M; Ndung'u T, 2009, 'Lack of Duffy antigen receptor for chemokines: no influence on HIV disease progression in an African treatment-naive population.', Cell Host Microbe, vol. 5, pp. 413 - 415, http://dx.doi.org/10.1016/j.chom.2009.04.009
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Singh A; Page T; Moore PL; Allgaier RL; Hiramen K; Coovadia HM; Walker BD; Morris L; Ndung'u T, 2009, 'Functional and genetic analysis of coreceptor usage by dualtropic HIV-1 subtype C isolates.', Virology, vol. 393, pp. 56 - 67, http://dx.doi.org/10.1016/j.virol.2009.07.021
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Brumme Z; Wang B; Nair K; Brumme C; de Pierres C; Reddy S; Julg B; Moodley E; Thobakgale C; Lu Z; van der Stok M; Bishop K; Mncube Z; Chonco F; Yuki Y; Frahm N; Brander C; Carrington M; Freedberg K; Kiepiela P; Goulder P; Walker B; Ndung'u T; Losina E, 2009, 'Impact of select immunologic and virologic biomarkers on CD4 cell count decrease in patients with chronic HIV-1 subtype C infection: results from Sinikithemba Cohort, Durban, South Africa.', Clin Infect Dis, vol. 49, pp. 956 - 964, http://dx.doi.org/10.1086/605503
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Lazaro E; Godfrey SB; Stamegna P; Ogbechie T; Kerrigan C; Zhang M; Walker BD; Le Gall S, 2009, 'Differential HIV epitope processing in monocytes and CD4 T cells affects cytotoxic T lymphocyte recognition.', J Infect Dis, vol. 200, pp. 236 - 243, http://dx.doi.org/10.1086/599837
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Ramduth D; Day CL; Thobakgale CF; Mkhwanazi NP; de Pierres C; Reddy S; van der Stok M; Mncube Z; Nair K; Moodley ES; Kaufmann DE; Streeck H; Coovadia HM; Kiepiela P; Goulder PJR; Walker BD, 2009, 'Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection.', PLoS One, vol. 4, pp. e5013, http://dx.doi.org/10.1371/journal.pone.0005013
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Chevalier M; Pyo A; Jolin JS; Addo M; Kwon DS; Toth I; Walker B; Streeck H, 2009, 'P16-31. Skewed HIV-1-specific CD4+ Th2 helper cell contribution in progressive HIV-1 infection', Retrovirology, vol. 6, http://dx.doi.org/10.1186/1742-4690-6-s3-p260
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Zuniga R; Mothe B; Llano A; Ibarrondo J; Daniels M; Farfan M; Suarez J; Szinger JJ; Hildebrand W; Lucchetti A; Heckerman D; Goulder P; Walker BD; Sanchez J; Korber BT; Brander C, 2009, 'S011-06 OA. HIV specific T cell responses and response patterns associated with viral control independent of classical non-progessor HLA class I alleles', Retrovirology, vol. 6, pp. O3 - O3, http://dx.doi.org/10.1186/1742-4690-6-s3-o3
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Julg B; Walker BD, 2009, 'The paradox of incomplete CD4+ cell count restoration despite successful antiretroviral treatment and the need to start highly active antiretroviral therapy early.', Clin Infect Dis, vol. 48, pp. 795 - 797, http://dx.doi.org/10.1086/597094
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Streeck H; Kwon D; Jolin JS; Trocha K; Chevalier M; Caron T; Law K; Pyo A; Toth I; Kaufmann DE; Rodig SJ; Walker BD; Altfeld M, 2009, 'OA031-04. Impairment of HIV-1-specific CD8+ T cell function by soluble epithelial adhesion molecules', Retrovirology, vol. 6, http://dx.doi.org/10.1186/1742-4690-6-s3-o22
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Prado JG; Prendergast A; Thobakgale C; Juarez C; Tudor-Williams A; Ndung'u T; Walker BD; Goulder P, 2009, 'P07-07. Non-progressive paediatric HIV infection is associated with virus attenuation and increase in CD8+ specific T cell responses over time', Retrovirology, vol. 6, http://dx.doi.org/10.1186/1742-4690-6-s3-p105
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Julg B; Williams KL; Reddy S; Bishop K; Goulder PJ; Ndung'u T; Walker BD, 2009, 'S04-06 OA. Polyvalent Gag-specific CD8 T-cells with enhanced functional properties are enriched in HIV-1 clade C infected individuals with lower viral loads', Retrovirology, vol. 6, http://dx.doi.org/10.1186/1742-4690-6-s3-o48
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Wright JK; Brockman MA; Brumme ZL; Walker BD; Goulder PJ; Ndung'u T, 2009, 'P09-09. Impact of immune-driven sequence variation in HIV-1 subtype C Gag-Protease on viral fitness and disease progression', Retrovirology, vol. 6, http://dx.doi.org/10.1186/1742-4690-6-s3-p122
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Honeyborne I; Leslie A; Crawford H; Rousseau CM; Mullins JI; Walker BD; Goulder P; Prado JG, 2009, 'P09-18. Cw*0303/0304 HIV specific CTL response toward GagYL9 select for HIV escape variants with low fitness that is compensated by intra-codon variation', Retrovirology, vol. 6, pp. P131 - P131, http://dx.doi.org/10.1186/1742-4690-6-s3-p131
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Porichis F; Kwon DS; Tighe DP; Pavlik DF; Kavanagh DG; Freeman GJ; Walker BD; Kaufmann DE, 2009, 'P16-08. Combined blockade of the PD-1 and IL-10 pathways synergistically enhance HIV-specific CD4 T cell functions', Retrovirology, vol. 6, http://dx.doi.org/10.1186/1742-4690-6-s3-p237
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Oniangue-Ndza C; Schneidewind A; Brockman MA; Brumme ZL; Boutwell CL; Wang YE; Brumme CJ; Power KA; Gladden AD; Kemper M; Le Gall S; Streeck H; Alter G; Altfeld M; Heckerman D; Walker BD; Allen TM, 2009, 'P09-10. Impact of CTL escape mutations in HIV-1 Nef on viral replication', Retrovirology, vol. 6, http://dx.doi.org/10.1186/1742-4690-6-s3-p123
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Miura T; Brockman MA; Schneidewind A; Lobritz M; Pereyra F; Rathod A; Block BL; Brumme ZL; Brumme CJ; Baker B; Rothchild AC; Li B; Trocha A; Cutrell E; Frahm N; Brander C; Toth I; Arts EJ; Allen TM; Walker BD, 2009, 'HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphocyte Recognition', Journal of Virology, vol. 83, pp. 5961 - 5961, http://dx.doi.org/10.1128/jvi.00579-09
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Jia M; Chen J; Hong K; Liu S; Zhang X; Zhao H; Altfeld M; Walker B; Yu X; Shao Y, 2009, 'P16-12. Relative dominance of Gag-specific cytotoxic T lymphocytes is associated with viral load inversely in HIV-1 clade B' infected Chinese', Retrovirology, vol. 6, http://dx.doi.org/10.1186/1742-4690-6-s3-p241
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Li C; Brumme ZL; Miura T; Rosato PC; Sela J; Brumme CJ; Heckerman D; Pereyra F; Walker BD; Brockman MA, 2009, 'P09-11. Reduced replication capacity of NL4-3 chimeric viruses encoding RT-Integrase sequences from HIV-1 elite controllers', Retrovirology, vol. 6, pp. P124 - P124, http://dx.doi.org/10.1186/1742-4690-6-s3-p124
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Lazaro E; Zhang S; Zhang M; Martinez S; Heckerman D; Walker BD; Le Gall S, 2009, 'SO4-05 OA. The intracellular production of HIV antigenic peptides is guided by predictable motifs and can be altered: implications for immunogen design', Retrovirology, vol. 6, pp. O47 - O47, http://dx.doi.org/10.1186/1742-4690-6-s3-o47
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Kwon DS; Angin M; Streeck H; Brockman MA; Tighe D; Pavlik D; Hongo T; Law K; Addo MM; Walker BD; Kaufmann DE, 2009, 'P16-55 LB. The role of CD4+ CD25+ regulatory T cells in the control of IL-10 mediated T cell impairment in chronic HIV Infection', Retrovirology, vol. 6, http://dx.doi.org/10.1186/1742-4690-6-s3-p408
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Streeck H; Jessen H; Kuecherer C; Li B; Jessen AB; Dupke S; Baumgarten A; Stahmer I; van Lunzen J; Altfeld M; Walker BD; Allen TM, 2009, 'Epidemiologically linked transmission of HIV-1 illustrates the impact of host genetics on virological outcome.', AIDS, vol. 23, pp. 259 - 262, http://dx.doi.org/10.1097/QAD.0b013e328315a78b
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Moodley ES; Thobakgale C; Ramkalawon P; Vanderstok M; Mncube Z; Bishop K; Reddy S; Chonco F; Walker B; Goulder P; Ndung'u T, 2009, 'P07-02. Cytotoxic T lymphocyte-mediated immune responses in HIV-1 clade C infected mother-child pairs', Retrovirology, vol. 6, http://dx.doi.org/10.1186/1742-4690-6-s3-p100
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Hersperger AR; Pereyra F; Demers K; Sheth P; Shin LY; Rodriguez B; Sieg SF; Teixeira-Johnson L; Goepfert PA; Lederman MM; Kaul R; Makedonas G; Walker BD; Betts MR, 2009, 'S03-06 OA. Rapid perforin upregulation by CD8 T cells in elite controllers as a correlate of immune-mediated control of HIV replication', Retrovirology, vol. 6, http://dx.doi.org/10.1186/1742-4690-6-s3-o45
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Angin M; Streeck H; Wen F; Pyo A; Trocha A; Toth I; Kwon D; Pereyra F; Alter G; Altfeld M; Walker BD; Addo MM, 2009, 'P16-18. Regulatory T cell frequencies correlate with T cell activation in chronic HIV-1 infection', Retrovirology, vol. 6, http://dx.doi.org/10.1186/1742-4690-6-s3-p247
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Hempel U; Buranapraditkun S; Chatkulkawin P; Pitakpolrat P; Phillips LC; Allgaier RL; Lorenzen S; Hildebrand WH; Leitner T; Matthews P; Goulder P; Walker BD; Ruxrungtham K; Allen TM, 2009, 'P16-07. HLA-B1302 is associated with viral control in clade CRF01_AE HIV-1 infection in Thailand', Retrovirology, vol. 6, http://dx.doi.org/10.1186/1742-4690-6-s3-p236
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Murphy RL; Autran B; Katlama C; Brucker G; Debre P; Calvez V; Clotet B; Clumeck N; Costagliola D; Deeks SG; Dorrell L; Gatell J; Haase A; Klein M; Lazzarin A; McMichael AJ; Papagno L; Schacker TW; Wain-Hobson S; Walker BD; Youle M, 2009, 'A step ahead on the HIV collaboratory.', Science, vol. 324, pp. 1264 - 1265, http://dx.doi.org/10.1126/science.324_1264b
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Rousseau CM; Lockhart DW; Listgarten J; Maley SN; Kadie C; Learn GH; Nickle DC; Heckerman DE; Deng W; Brander C; Ndung'u T; Coovadia H; Goulder PJR; Korber BT; Walker BD; Mullins JI, 2009, 'Rare HLA drive additional HIV evolution compared to more frequent alleles.', AIDS Res Hum Retroviruses, vol. 25, pp. 297 - 303, http://dx.doi.org/10.1089/aid.2008.0208
    Journal articles | 2009
    Dr Bruce Duncan Walker
    Quigley M; Pereyra F; Nilsson B; Eichbaum Q; Julg B; Jesneck J; Brosnahan K; Russell K; Toth I; Piechocka-Trocha A; Shin H; Freeman GJ; Wherry EJ; Walker BD; Ebert BL; Haining WN, 2009, 'Integrative Genomic Analysis of HIV-Specific CD8+ T Cells Reveals That PD-1 Inhibits T Cell Function by Upregulating the AP-1 Transcription Factor BATF.', Blood, vol. 114, pp. 916 - 916, http://dx.doi.org/10.1182/blood.v114.22.916.916
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Kasprowicz V; Schulze Zur Wiesch J; Kuntzen T; Nolan BE; Longworth S; Berical A; Blum J; McMahon C; Reyor LL; Elias N; Kwok WW; McGovern BG; Freeman G; Chung RT; Klenerman P; Lewis-Ximenez L; Walker BD; Allen TM; Kim AY; Lauer GM, 2008, 'High level of PD-1 expression on hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells during acute HCV infection, irrespective of clinical outcome.', J Virol, vol. 82, pp. 3154 - 3160, http://dx.doi.org/10.1128/JVI.02474-07
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Walker BD; Burton DR, 2008, 'Toward an AIDS vaccine.', Science, vol. 320, pp. 760 - 764, http://dx.doi.org/10.1126/science.1152622
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Pereyra F; Addo MM; Kaufmann DE; Liu Y; Miura T; Rathod A; Baker B; Trocha A; Rosenberg R; Mackey E; Ueda P; Lu Z; Cohen D; Wrin T; Petropoulos CJ; Rosenberg ES; Walker BD, 2008, 'Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy.', J Infect Dis, vol. 197, pp. 563 - 571, http://dx.doi.org/10.1086/526786
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Lichterfeld M; Mou D; Cung TDH; Williams KL; Waring MT; Huang J; Pereyra F; Trocha A; Freeman GJ; Rosenberg ES; Walker BD; Yu XG, 2008, 'Telomerase activity of HIV-1-specific CD8+ T cells: constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressors.', Blood, vol. 112, pp. 3679 - 3687, http://dx.doi.org/10.1182/blood-2008-01-135442
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Schneidewind A; Brockman MA; Sidney J; Wang YE; Chen H; Suscovich TJ; Li B; Adam RI; Allgaier RL; Mothé BR; Kuntzen T; Oniangue-Ndza C; Trocha A; Yu XG; Brander C; Sette A; Walker BD; Allen TM, 2008, 'Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid.', J Virol, vol. 82, pp. 5594 - 5605, http://dx.doi.org/10.1128/JVI.02356-07
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Prendergast A; Mphatswe W; Tudor-Williams G; Rakgotho M; Pillay V; Thobakgale C; McCarthy N; Morris L; Walker BD; Goulder P, 2008, 'Early virological suppression with three-class antiretroviral therapy in HIV-infected African infants.', AIDS, vol. 22, pp. 1333 - 1343, http://dx.doi.org/10.1097/QAD.0b013e32830437df
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Marconi VC; Sunpath H; Lu Z; Gordon M; Koranteng-Apeagyei K; Hampton J; Carpenter S; Giddy J; Ross D; Holst H; Losina E; Walker BD; Kuritzkes DR; South Africa Resistance Cohort Study Team , 2008, 'Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa.', Clin Infect Dis, vol. 46, pp. 1589 - 1597, http://dx.doi.org/10.1086/587109
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Minkis K; Kavanagh DG; Alter G; Bogunovic D; O'Neill D; Adams S; Pavlick A; Walker BD; Brockman MA; Gandhi RT; Bhardwaj N, 2008, 'Type 2 Bias of T cells expanded from the blood of melanoma patients switched to type 1 by IL-12p70 mRNA-transfected dendritic cells.', Cancer Res, vol. 68, pp. 9441 - 9450, http://dx.doi.org/10.1158/0008-5472.CAN-08-0900
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Kuntzen T; Timm J; Berical A; Lennon N; Berlin AM; Young SK; Lee B; Heckerman D; Carlson J; Reyor LL; Kleyman M; McMahon CM; Birch C; Schulze Zur Wiesch J; Ledlie T; Koehrsen M; Kodira C; Roberts AD; Lauer GM; Rosen HR; Bihl F; Cerny A; Spengler U; Liu Z; Kim AY; Xing Y; Schneidewind A; Madey MA; Fleckenstein JF; Park VM; Galagan JE; Nusbaum C; Walker BD; Lake-Bakaar GV; Daar ES; Jacobson IM; Gomperts ED; Edlin BR; Donfield SM; Chung RT; Talal AH; Marion T; Birren BW; Henn MR; Allen TM, 2008, 'Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients.', Hepatology, vol. 48, pp. 1769 - 1778, http://dx.doi.org/10.1002/hep.22549
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Matthews PC; Prendergast A; Leslie A; Crawford H; Payne R; Rousseau C; Rolland M; Honeyborne I; Carlson J; Kadie C; Brander C; Bishop K; Mlotshwa N; Mullins JI; Coovadia H; Ndung'u T; Walker BD; Heckerman D; Goulder PJR, 2008, 'Central role of reverting mutations in HLA associations with human immunodeficiency virus set point.', J Virol, vol. 82, pp. 8548 - 8559, http://dx.doi.org/10.1128/JVI.00580-08
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Brumme ZL; Tao I; Szeto S; Brumme CJ; Carlson JM; Chan D; Kadie C; Frahm N; Brander C; Walker B; Heckerman D; Harrigan PR, 2008, 'Human leukocyte antigen-specific polymorphisms in HIV-1 Gag and their association with viral load in chronic untreated infection.', AIDS, vol. 22, pp. 1277 - 1286, http://dx.doi.org/10.1097/QAD.0b013e3283021a8c
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Miura T; Brockman MA; Brumme CJ; Brumme ZL; Carlson JM; Pereyra F; Trocha A; Addo MM; Block BL; Rothchild AC; Baker BM; Flynn T; Schneidewind A; Li B; Wang YE; Heckerman D; Allen TM; Walker BD, 2008, 'Genetic characterization of human immunodeficiency virus type 1 in elite controllers: lack of gross genetic defects or common amino acid changes.', J Virol, vol. 82, pp. 8422 - 8430, http://dx.doi.org/10.1128/JVI.00535-08
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Carlson JM; Brumme ZL; Rousseau CM; Brumme CJ; Matthews P; Kadie C; Mullins JI; Walker BD; Harrigan PR; Goulder PJR; Heckerman D, 2008, 'Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag.', PLoS Comput Biol, vol. 4, pp. e1000225, http://dx.doi.org/10.1371/journal.pcbi.1000225
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Alter G; Rihn S; Streeck H; Teigen N; Piechocka-Trocha A; Moss K; Cohen K; Meier A; Pereyra F; Walker B; Altfeld M, 2008, 'Ligand-independent exhaustion of killer immunoglobulin-like receptor-positive CD8+ T cells in human immunodeficiency virus type 1 infection.', J Virol, vol. 82, pp. 9668 - 9677, http://dx.doi.org/10.1128/JVI.00341-08
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Frahm N; Nickle DC; Linde CH; Cohen DE; Zuñiga R; Lucchetti A; Roach T; Walker BD; Allen TM; Korber BT; Mullins JI; Brander C, 2008, 'Increased detection of HIV-specific T cell responses by combination of central sequences with comparable immunogenicity.', AIDS, vol. 22, pp. 447 - 456, http://dx.doi.org/10.1097/QAD.0b013e3282f42412
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Autran B; Murphy RL; Costagliola D; Tubiana R; Clotet B; Gatell J; Staszewski S; Wincker N; Assoumou L; El-Habib R; Calvez V; Walker B; Katlama C; ORVACS Study Group , 2008, 'Greater viral rebound and reduced time to resume antiretroviral therapy after therapeutic immunization with the ALVAC-HIV vaccine (vCP1452).', AIDS, vol. 22, pp. 1313 - 1322, http://dx.doi.org/10.1097/QAD.0b013e3282fdce94
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Listgarten J; Brumme Z; Kadie C; Xiaojiang G; Walker B; Carrington M; Goulder P; Heckerman D, 2008, 'Statistical resolution of ambiguous HLA typing data.', PLoS Comput Biol, vol. 4, pp. e1000016, http://dx.doi.org/10.1371/journal.pcbi.1000016
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Day CL; Mkhwanazi N; Reddy S; Mncube Z; van der Stok M; Klenerman P; Walker BD, 2008, 'Detection of polyfunctional Mycobacterium tuberculosis-specific T cells and association with viral load in HIV-1-infected persons.', J Infect Dis, vol. 197, pp. 990 - 999, http://dx.doi.org/10.1086/529048
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Kaufmann DE; Walker BD, 2008, 'Programmed death-1 as a factor in immune exhaustion and activation in HIV infection.', Curr Opin HIV AIDS, vol. 3, pp. 362 - 367, http://dx.doi.org/10.1097/COH.0b013e3282f9ae8b
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Rolland M; Heckerman D; Deng W; Rousseau CM; Coovadia H; Bishop K; Goulder PJR; Walker BD; Brander C; Mullins JI, 2008, 'Broad and Gag-biased HIV-1 epitope repertoires are associated with lower viral loads.', PLoS One, vol. 3, pp. e1424, http://dx.doi.org/10.1371/journal.pone.0001424
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Joseph A; Zheng JH; Follenzi A; Dilorenzo T; Sango K; Hyman J; Chen K; Piechocka-Trocha A; Brander C; Hooijberg E; Vignali DA; Walker BD; Goldstein H, 2008, 'Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activity.', J Virol, vol. 82, pp. 3078 - 3089, http://dx.doi.org/10.1128/JVI.01812-07
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Rousseau CM; Daniels MG; Carlson JM; Kadie C; Crawford H; Prendergast A; Matthews P; Payne R; Rolland M; Raugi DN; Maust BS; Learn GH; Nickle DC; Coovadia H; Ndung'u T; Frahm N; Brander C; Walker BD; Goulder PJR; Bhattacharya T; Heckerman DE; Korber BT; Mullins JI, 2008, 'HLA class I-driven evolution of human immunodeficiency virus type 1 subtype c proteome: immune escape and viral load.', J Virol, vol. 82, pp. 6434 - 6446, http://dx.doi.org/10.1128/JVI.02455-07
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Streeck H; Brumme ZL; Anastario M; Cohen KW; Jolin JS; Meier A; Brumme CJ; Rosenberg ES; Alter G; Allen TM; Walker BD; Altfeld M, 2008, 'Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells.', PLoS Med, vol. 5, pp. e100, http://dx.doi.org/10.1371/journal.pmed.0050100
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Kasprowicz V; Ward SM; Turner A; Grammatikos A; Nolan BE; Lewis-Ximenez L; Sharp C; Woodruff J; Fleming VM; Sims S; Walker BD; Sewell AK; Lauer GM; Klenerman P, 2008, 'Defining the directionality and quality of influenza virus-specific CD8+ T cell cross-reactivity in individuals infected with hepatitis C virus.', J Clin Invest, vol. 118, pp. 1143 - 1153, http://dx.doi.org/10.1172/JCI33082
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Ngumbela KC; Day CL; Mncube Z; Nair K; Ramduth D; Thobakgale C; Moodley E; Reddy S; de Pierres C; Mkhwanazi N; Bishop K; van der Stok M; Ismail N; Honeyborne I; Crawford H; Kavanagh DG; Rousseau C; Nickle D; Mullins J; Heckerman D; Korber B; Coovadia H; Kiepiela P; Goulder PJR; Walker BD, 2008, 'Targeting of a CD8 T cell env epitope presented by HLA-B*5802 is associated with markers of HIV disease progression and lack of selection pressure.', AIDS Res Hum Retroviruses, vol. 24, pp. 72 - 82, http://dx.doi.org/10.1089/aid.2007.0124
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Huang S; Dunkley-Thompson J; Tang Y; Macklin EA; Steel-Duncan J; Singh-Minott I; Ryland EG; Smikle M; Walker BD; Christie CDC; Feeney ME, 2008, 'Deficiency of HIV-Gag-specific T cells in early childhood correlates with poor viral containment.', J Immunol, vol. 181, pp. 8103 - 8111, http://dx.doi.org/10.4049/jimmunol.181.11.8103
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Brumme Z; Brumme C; Carlson J; Streeck H; John M; Eichbaum Q; Block B; Baker B; Kadie C; Markowitz M; Jessen H; Kelleher AD; Rosenberg E; Kaldor JM; Yuki Y; Carrington M; Allen TM; Mallal SA; Altfeld M; Heckerman D; Walker BD, 2008, 'Marked epitope- and allele- specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection', Journal of Virology, vol. 82, pp. 9216 - 9227, http://dx.doi.org/10.1128/JVI.01041-08
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Schulze zur Wiesch JC; Kim AY; Kasprowicz V; Timm J; Kuntzen T; Nolan BE; Longworth S; Berical A; Lohse AW; Chung RT; kasprowicz V; Walker B; Allen T; Lauer GM, 2008, 'CD4 functionality determines outcome in acute HCV re-infection', Zeitschrift für Gastroenterologie, vol. 46, http://dx.doi.org/10.1055/s-2008-1037622
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Tay A; Walker B; Kuchar D; Thorburn C; Fansworth A; Spratt P; Jansz P; Granger E; Macdonald P; Hayward C; Kotlyar E; Keogh A; Subbiah R, 2008, 'Late Onset High-grade Atrioventricular Block Post-Cardiac Transplantion: A Single Centre Experience', Heart, Lung and Circulation, vol. 17, pp. S113 - S114, http://dx.doi.org/10.1016/j.hlc.2008.05.272
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Eichbaum Q; Block B; Brumme Z; Streeck H; Jolin J; Jessen H; Walker B, 2008, 'Su.45. Longitudinal Evaluation of CTL Responses and HIV Sequence Evolution in Optimally Described HIV-1 CTL Epitopes During Acute/Early HIV-1 Infection', Clinical Immunology, vol. 127, pp. S139 - S139, http://dx.doi.org/10.1016/j.clim.2008.03.396
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Prendergast A; Mphatswe W; Tudor-Williams G; Blanckenberg N; Cengimbo A; Jeena P; Rakgotho M; Pillay V; Thobakgale C; Reddy S; Mncube Z; Vanderstok M; McCarthy N; Dong K; Coovadia H; Morris L; Walker BD; Goulder P, 2008, 'Early virological suppression despite high frequency NNRTI resistance following perinatal prophylaxis in HIV-infected African infants', Retrovirology, vol. 5, pp. O27 - O27, http://dx.doi.org/10.1186/1742-4690-5-s1-o27
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Crawford H; Prado JG; Leslie A; Hué S; Honeyborne I; Reddy S; van der Stok M; Mncube Z; Brander C; Rousseau C; Mullins JI; Kaslow R; Goepfert P; Allen S; Hunter E; Mulenga J; Kiepiela P; Walker BD; Goulder PJR, 2008, 'Compensatory Mutation Partially Restores Fitness and Delays Reversion of Escape Mutation within the Immunodominant HLA-B*5703-Restricted Gag Epitope in Chronic Human Immunodeficiency Virus Type 1 Infection', Journal of Virology, vol. 82, pp. 3161 - 3161, http://dx.doi.org/10.1128/jvi.02750-07
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Lazaro E; Godfrey SB; Stamegna P; Ho J; Walker B; Gall SL, 2008, 'Su.40. Differential Antigen Processing Activities of PBMC Subsets Targeted by HIV Modulate HIV Epitope Production', Clinical Immunology, vol. 127, pp. S137 - S137, http://dx.doi.org/10.1016/j.clim.2008.03.391
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Listgarten J; Brumme Z; Kadie C; Xiaojiang G; Walker B; Carrington M; Goulder P; Heckerman D, 2008, '168-P: In silico resolution of ambiguous HLA typing data', Human Immunology, vol. 69, pp. S91 - S91, http://dx.doi.org/10.1016/j.humimm.2008.08.187
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Zhuang Y; Sun Y; Zhai S; Huang D; Zhao S; Wang S; Kang W; Li X; Walker BD; Altfeld M; Yu XG, 2008, 'Relative dominance of Env-gp41-specific cytotoxic T lymphocytes responses in HIV-1 advanced infection.', Curr HIV Res, vol. 6, pp. 239 - 245, http://dx.doi.org/10.2174/157016208784324921
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Ramduth D; Thobakgale CF; Mkhwanazi NP; De Pierres C; Reddy S; van der Stok M; Mncube Z; Mphatswe W; Blanckenberg N; Cengimbo A; Prendergast A; Tudor-Williams G; Dong K; Jeena P; Coovadia HM; Day CL; Kiepiela P; Goulder PJR; Walker BD, 2008, 'Detection of HIV type 1 gag-specific CD4(+) T cell responses in acutely infected infants.', AIDS Res Hum Retroviruses, vol. 24, pp. 265 - 270, http://dx.doi.org/10.1089/aid.2007.0096
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Schulzezur Wiesch J; Listgarden J; Li B; Nawar H; Kasprowicz V; Nolan B; Blum J; Lewis-Ximenez L; McGovern B; Kuntzen T; Kwok B; Allen T; Sette A; Lohse A; Walker B; Chung R; Kim A; Lauer G, 2008, '622 COMPREHENSIVE ASSESSMENT OF HCV CD4+ EPITOPES THROUGH CONVENTIONAL MAPPING COMBINED WITH COMPUTATIONAL ANALYSIS', Journal of Hepatology, vol. 48, pp. S231 - S232, http://dx.doi.org/10.1016/s0168-8278(08)60624-8
    Journal articles | 2008
    Dr Bruce Duncan Walker
    Elsik M; Pfluger H; Hayward C; Walker B; Prior D; Yii M; Kistler P; Broughton A; Toogood G; Wolfe R; Taylor A; Krum H, 2008, 'Do Baseline Collagen Markers Predict Outcomes in Chronic Heart Failure Patients with and Without Cardiac Resynchronisation Therapy? Insights from the Triple R Study', Heart, Lung and Circulation, vol. 17, pp. S153 - S153, http://dx.doi.org/10.1016/j.hlc.2008.05.363
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Lichterfeld M; Kavanagh DG; Williams KL; Moza B; Mui SK; Miura T; Sivamurthy R; Allgaier R; Pereyra F; Trocha A; Feeney M; Gandhi RT; Rosenberg ES; Altfeld M; Allen TM; Allen R; Walker BD; Sundberg EJ; Yu XG, 2007, 'A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells.', J Exp Med, vol. 204, pp. 2813 - 2824, http://dx.doi.org/10.1084/jem.20061865
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Deeks SG; Walker BD, 2007, 'Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy.', Immunity, vol. 27, pp. 406 - 416, http://dx.doi.org/10.1016/j.immuni.2007.08.010
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Mphatswe W; Blanckenberg N; Tudor-Williams G; Prendergast A; Thobakgale C; Mkhwanazi N; McCarthy N; Walker BD; Kiepiela P; Goulder P, 2007, 'High frequency of rapid immunological progression in African infants infected in the era of perinatal HIV prophylaxis.', AIDS, vol. 21, pp. 1253 - 1261, http://dx.doi.org/10.1097/QAD.0b013e3281a3bec2
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Honeyborne I; Prendergast A; Pereyra F; Leslie A; Crawford H; Payne R; Reddy S; Bishop K; Moodley E; Nair K; van der Stok M; McCarthy N; Rousseau CM; Addo M; Mullins JI; Brander C; Kiepiela P; Walker BD; Goulder PJR, 2007, 'Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopes.', J Virol, vol. 81, pp. 3667 - 3672, http://dx.doi.org/10.1128/JVI.02689-06
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Frahm N; Yusim K; Suscovich TJ; Adams S; Sidney J; Hraber P; Hewitt HS; Linde CH; Kavanagh DG; Woodberry T; Henry LM; Faircloth K; Listgarten J; Kadie C; Jojic N; Sango K; Brown NV; Pae E; Zaman MT; Bihl F; Khatri A; John M; Mallal S; Marincola FM; Walker BD; Sette A; Heckerman D; Korber BT; Brander C, 2007, 'Extensive HLA class I allele promiscuity among viral CTL epitopes.', Eur J Immunol, vol. 37, pp. 2419 - 2433, http://dx.doi.org/10.1002/eji.200737365
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Kiepiela P; Ngumbela K; Thobakgale C; Ramduth D; Honeyborne I; Moodley E; Reddy S; de Pierres C; Mncube Z; Mkhwanazi N; Bishop K; van der Stok M; Nair K; Khan N; Crawford H; Payne R; Leslie A; Prado J; Prendergast A; Frater J; McCarthy N; Brander C; Learn GH; Nickle D; Rousseau C; Coovadia H; Mullins JI; Heckerman D; Walker BD; Goulder P, 2007, 'CD8+ T-cell responses to different HIV proteins have discordant associations with viral load.', Nat Med, vol. 13, pp. 46 - 53, http://dx.doi.org/10.1038/nm1520
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Lichterfeld M; Yu XG; Mui SK; Williams KL; Trocha A; Brockman MA; Allgaier RL; Waring MT; Koibuchi T; Johnston MN; Cohen D; Allen TM; Rosenberg ES; Walker BD; Altfeld M, 2007, 'Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infection.', J Virol, vol. 81, pp. 4199 - 4214, http://dx.doi.org/10.1128/JVI.01388-06
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Crawford H; Prado JG; Leslie A; Hué S; Honeyborne I; Reddy S; van der Stok M; Mncube Z; Brander C; Rousseau C; Mullins JI; Kaslow R; Goepfert P; Allen S; Hunter E; Mulenga J; Kiepiela P; Walker BD; Goulder PJR, 2007, 'Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection.', J Virol, vol. 81, pp. 8346 - 8351, http://dx.doi.org/10.1128/JVI.00465-07
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Fischer W; Perkins S; Theiler J; Bhattacharya T; Yusim K; Funkhouser R; Kuiken C; Haynes B; Letvin NL; Walker BD; Hahn BH; Korber BT, 2007, 'Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants.', Nat Med, vol. 13, pp. 100 - 106, http://dx.doi.org/10.1038/nm1461
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Addo MM; Draenert R; Rathod A; Verrill CL; Davis BT; Gandhi RT; Robbins GK; Basgoz NO; Stone DR; Cohen DE; Johnston MN; Flynn T; Wurcel AG; Rosenberg ES; Altfeld M; Walker BD, 2007, 'Fully differentiated HIV-1 specific CD8+ T effector cells are more frequently detectable in controlled than in progressive HIV-1 infection.', PLoS One, vol. 2, pp. e321, http://dx.doi.org/10.1371/journal.pone.0000321
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Brumme ZL; Brumme CJ; Heckerman D; Korber BT; Daniels M; Carlson J; Kadie C; Bhattacharya T; Chui C; Szinger J; Mo T; Hogg RS; Montaner JSG; Frahm N; Brander C; Walker BD; Harrigan PR, 2007, 'Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1.', PLoS Pathog, vol. 3, pp. e94, http://dx.doi.org/10.1371/journal.ppat.0030094
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Bhattacharya T; Daniels M; Heckerman D; Foley B; Frahm N; Kadie C; Carlson J; Yusim K; McMahon B; Gaschen B; Mallal S; Mullins JI; Nickle DC; Herbeck J; Rousseau C; Learn GH; Miura T; Brander C; Walker B; Korber B, 2007, 'Founder effects in the assessment of HIV polymorphisms and HLA allele associations.', Science, vol. 315, pp. 1583 - 1586, http://dx.doi.org/10.1126/science.1131528
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Le Gall S; Stamegna P; Walker BD, 2007, 'Portable flanking sequences modulate CTL epitope processing.', J Clin Invest, vol. 117, pp. 3563 - 3575, http://dx.doi.org/10.1172/JCI32047
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Streeck H; Lichterfeld M; Alter G; Meier A; Teigen N; Yassine-Diab B; Sidhu H; Little S; Kelleher AD; Routy J; Rosenberg E; Sekaly R; Walker BD; Altfeld M, 2007, 'Recognition of a defined region within p24 Gag by CD8(+) T cells during primary human immunodeficiency virus type I infection in individuals expressing protective HLA class I alleles', Journal of Virology, vol. 81, pp. 7725 - 7731, http://dx.doi.org/10.1128/JVI.00708-07
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Rousseau CM; Learn GH; Bhattacharya T; Nickle DC; Heckerman D; Chetty S; Brander C; Goulder PJR; Walker BD; Kiepiela P; Korber BT; Mullins JI, 2007, 'Extensive intrasubtype recombination in South African human immunodeficiency virus type 1 subtype C infections.', J Virol, vol. 81, pp. 4492 - 4500, http://dx.doi.org/10.1128/JVI.02050-06
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Thobakgale CF; Ramduth D; Reddy S; Mkhwanazi N; de Pierres C; Moodley E; Mphatswe W; Blanckenberg N; Cengimbo A; Prendergast A; Tudor-Williams G; Dong K; Jeena P; Kindra G; Bobat R; Coovadia H; Kiepiela P; Walker BD; Goulder PJR, 2007, 'Human immunodeficiency virus-specific CD8+ T-cell activity is detectable from birth in the majority of in utero-infected infants.', J Virol, vol. 81, pp. 12775 - 12784, http://dx.doi.org/10.1128/JVI.00624-07
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Timm J; Neukamm M; Kuntzen T; Kim AY; Chung RT; Brander C; Lauer GM; Walker BD; Allen TM, 2007, 'Characterization of full-length hepatitis C virus genotype 4 sequences.', J Viral Hepat, vol. 14, pp. 330 - 337, http://dx.doi.org/10.1111/j.1365-2893.2006.00792.x
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Rolland M; Nickle DC; Deng W; Frahm N; Brander C; Learn GH; Heckerman D; Jojic N; Jojic V; Walker BD; Mullins JI, 2007, 'Recognition of HIV-1 peptides by host CTL is related to HIV-1 similarity to human proteins.', PLoS One, vol. 2, pp. e823, http://dx.doi.org/10.1371/journal.pone.0000823
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Yu XG; Lichterfeld M; Chetty S; Williams KL; Mui SK; Miura T; Frahm N; Feeney ME; Tang Y; Pereyra F; Labute MX; Pfafferott K; Leslie A; Crawford H; Allgaier R; Hildebrand W; Kaslow R; Brander C; Allen TM; Rosenberg ES; Kiepiela P; Vajpayee M; Goepfert PA; Altfeld M; Goulder PJR; Walker BD, 2007, 'Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes.', J Virol, vol. 81, pp. 1619 - 1631, http://dx.doi.org/10.1128/JVI.01580-06
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Brainard DM; Tager AM; Misdraji J; Frahm N; Lichterfeld M; Draenert R; Brander C; Walker BD; Luster AD, 2007, 'Decreased CXCR3+ CD8 T cells in advanced human immunodeficiency virus infection suggest that a homing defect contributes to cytotoxic T-lymphocyte dysfunction.', J Virol, vol. 81, pp. 8439 - 8450, http://dx.doi.org/10.1128/JVI.00199-07
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Day CL; Kiepiela P; Leslie AJ; van der Stok M; Nair K; Ismail N; Honeyborne I; Crawford H; Coovadia HM; Goulder PJR; Walker BD; Klenerman P, 2007, 'Proliferative capacity of epitope-specific CD8 T-cell responses is inversely related to viral load in chronic human immunodeficiency virus type 1 infection.', J Virol, vol. 81, pp. 434 - 438, http://dx.doi.org/10.1128/JVI.01754-06
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Sabado RL; Babcock E; Kavanagh DG; Tjomsland V; Walker BD; Lifson JD; Bhardwaj N; Larsson M, 2007, 'Pathways utilized by dendritic cells for binding, uptake, processing and presentation of antigens derived from HIV-1.', Eur J Immunol, vol. 37, pp. 1752 - 1763, http://dx.doi.org/10.1002/eji.200636981
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Schulze Zur Wiesch J; Lauer GM; Timm J; Kuntzen T; Neukamm M; Berical A; Jones AM; Nolan BE; Longworth SA; Kasprowicz V; McMahon C; Wurcel A; Lohse AW; Lewis-Ximenez LL; Chung RT; Kim AY; Allen TM; Walker BD, 2007, 'Immunologic evidence for lack of heterologous protection following resolution of HCV in patients with non-genotype 1 infection.', Blood, vol. 110, pp. 1559 - 1569, http://dx.doi.org/10.1182/blood-2007-01-069583
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Gasser O; Bihl FK; Wolbers M; Loggi E; Steffen I; Hirsch HH; Günthard HF; Walker BD; Brander C; Battegay M; Hess C; Swiss HIV Cohort Study , 2007, 'HIV patients developing primary CNS lymphoma lack EBV-specific CD4+ T cell function irrespective of absolute CD4+ T cell counts.', PLoS Med, vol. 4, pp. e96, http://dx.doi.org/10.1371/journal.pmed.0040096
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Brockman MA; Schneidewind A; Lahaie M; Schmidt A; Miura T; Desouza I; Ryvkin F; Derdeyn CA; Allen S; Hunter E; Mulenga J; Goepfert PA; Walker BD; Allen TM, 2007, 'Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A.', J Virol, vol. 81, pp. 12608 - 12618, http://dx.doi.org/10.1128/JVI.01369-07
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Otway R; Vandenberg JI; Guo G; Varghese A; Castro ML; Liu JJ; Zhao J; Bursill JA; Wyse KR; Crotty H; Baddeley O; Walker BD; Kuchar D; Thorburn CW; Fatkin D, 2007, 'Stretch-sensitive KCNQ1 mutation - A link between genetic and environmental factors in the pathogenesis of atrial fibrillation?', Journal of the American College of Cardiology, vol. 49, pp. 578 - 586, http://dx.doi.org/10.1016/j.jacc.2006.09.044
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Frahm N; Kaufmann DE; Yusim K; Muldoon M; Kesmir C; Linde CH; Fischer W; Allen TM; Li B; McMahon BH; Faircloth KL; Hewitt HS; Mackey EW; Miura T; Khatri A; Wolinsky S; McMichael A; Funkhouser RK; Walker BD; Brander C; Korber BT, 2007, 'Increased sequence diversity coverage improves detection of HIV-specific T cell responses.', J Immunol, vol. 179, pp. 6638 - 6650, http://dx.doi.org/10.4049/jimmunol.179.10.6638
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Walker BD, 2007, 'Elite control of HIV Infection: implications for vaccines and treatment.', Top HIV Med, vol. 15, pp. 134 - 136, https://www.ncbi.nlm.nih.gov/pubmed/17720999
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Brumme ZL; Brumme CJ; Heckerman D; Korber BT; Daniels M; Carlson J; Kadie C; Bhattacharya T; Chui C; Szinger J; Mo T; Hogg RS; Montaner JSG; Frahm N; Brander C; Walker BD; Harrigan PR, 2007, 'Correction: Evidence of Differential HLA Class I-Mediated Viral Evolution in Functional and Accessory/Regulatory Genes of HIV-1', PLoS Pathogens, vol. 3, pp. e121 - e121, http://dx.doi.org/10.1371/journal.ppat.0030121
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Schulze zur Wiesch J; Timm J; Kuntzen T; Neukamm M; Kim A; Kasprowicz V; Chung RT; Lohse A; Allen T; Lauer G; Walker B, 2007, 'Immunologic evidence for lack of heterologous protection following resolution of HCV infection', Zeitschrift für Gastroenterologie, vol. 45, http://dx.doi.org/10.1055/s-2007-967913
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Wang S; Sun Y; Zhai S; Zhuang Y; Zhao S; Kang W; Li X; Huang D; Yu XG; Walker BD; Altfeld MA, 2007, 'Identification of HLA-A11-restricted HIV-1-specific cytotoxic T-lymphocyte epitopes in China.', Curr HIV Res, vol. 5, pp. 119 - 128, http://dx.doi.org/10.2174/157016207779316404
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Yu XG; Lichterfeld M; Williams KL; Martinez-Picado J; Walker BD, 2007, 'Random T-cell receptor recruitment in human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells from genetically identical twins infected with the same HIV-1 strain.', J Virol, vol. 81, pp. 12666 - 12669, http://dx.doi.org/10.1128/JVI.01450-07
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Streeck H; Schweighardt B; Jessen H; Allgaier RL; Wrin T; Stawiski EW; Jessen AB; Allen TM; Walker BD; Altfeld M, 2007, 'Loss of HIV-1-specific T-cell responses associated with very rapid HIV-1 disease progression.', AIDS, vol. 21, pp. 889 - 891, http://dx.doi.org/10.1097/QAD.0b013e3280f77439
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Chen J; Hong K; Jia M; Liu H; Zhang Y; Liu S; Zhang X; Zhao H; Peng H; Ma P; Xing H; Ruan Y; Williams KL; Yu XG; Altfeld M; Walker BD; Shao Y, 2007, 'Human immunodeficiency virus type 1 specific cytotoxic T lymphocyte responses in Chinese infected with HIV-1 B'/C Recombinant (CRF07_BC).', Retrovirology, vol. 4, pp. 62, http://dx.doi.org/10.1186/1742-4690-4-62
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Kaufmann DE; Walker BD, 2007, 'Treatment interruption to boost specific HIV immunity in acute infection.', Curr Opin HIV AIDS, vol. 2, pp. 21 - 25, http://dx.doi.org/10.1097/COH.0b013e3280119275
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Zhao S; Zhai S; Zhuang Y; Wang S; Huang D; Kang W; Li X; Yu XG; Walker BD; Altfeld MA; Sun Y, 2007, 'Inter-clade cross-reactivity of HIV-1-specific T cell responses in human immunodeficiency virus type 1 infection in China.', Curr HIV Res, vol. 5, pp. 251 - 259, http://dx.doi.org/10.2174/157016207780076995
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Miura T; Ngumbela K; Ramduth D; Pereyra F; Walker B, 2007, 'HIV controllers.', IAVI Rep, vol. 11, pp. 1 - 10, https://www.ncbi.nlm.nih.gov/pubmed/20213861
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Schulze zur Wiesch J; Kasprowicz V; Kim AY; Kuntzen T; Longworth SA; Nolan BE; Wurcel AG; McMahon C; Allen TM; McGovern B; Lewis-Ximenes L; Chung RT; Kwok W; Walker BD; Lauer GM, 2007, '[463] DETECTION OF CD4+ T CELL RESPONSES IN PATIENTS WITH ACUTE HCV INFECTION IRRESPECTIVE OF CLINICAL OUTCOME', Journal of Hepatology, vol. 46, pp. S176 - S176, http://dx.doi.org/10.1016/s0168-8278(07)62061-3
    Journal articles | 2007
    Dr Bruce Duncan Walker
    Wright SP; Walker B; Thorburn C; Ali F; Feneley M, 2007, 'Development of an Echocardiography Guided Programme for Screening and Optimization of Cardiac Resynchronization Therapy Patients: Initial Experience at St Vincent's Hospital, Sydney', Heart, Lung and Circulation, vol. 16, pp. S97 - S98, http://dx.doi.org/10.1016/j.hlc.2007.06.250
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Kavanagh DG; Kaufmann DE; Sunderji S; Frahm N; Le Gall S; Boczkowski D; Rosenberg ES; Stone DR; Johnston MN; Wagner BS; Zaman MT; Brander C; Gilboa E; Walker BD; Bhardwaj N, 2006, 'Expansion of HIV-specific CD4+ and CD8+ T cells by dendritic cells transfected with mRNA encoding cytoplasm- or lysosome-targeted Nef.', Blood, vol. 107, pp. 1963 - 1969, http://dx.doi.org/10.1182/blood-2005-04-1513
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Altfeld M; Kalife ET; Qi Y; Streeck H; Lichterfeld M; Johnston MN; Burgett N; Swartz ME; Yang A; Alter G; Yu XG; Meier A; Rockstroh JK; Allen TM; Jessen H; Rosenberg ES; Carrington M; Walker BD, 2006, 'HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1.', PLoS Med, vol. 3, pp. e403, http://dx.doi.org/10.1371/journal.pmed.0030403
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Kassutto S; Maghsoudi K; Johnston MN; Robbins GK; Burgett NC; Sax PE; Cohen D; Pae E; Davis B; Zachary K; Basgoz N; D'agata EMC; DeGruttola V; Walker BD; Rosenberg ES, 2006, 'Longitudinal analysis of clinical markers following antiretroviral therapy initiated during acute or early HIV type 1 infection.', Clin Infect Dis, vol. 42, pp. 1024 - 1031, http://dx.doi.org/10.1086/500410
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Frahm N; Kiepiela P; Adams S; Linde CH; Hewitt HS; Sango K; Feeney ME; Addo MM; Lichterfeld M; Lahaie MP; Pae E; Wurcel AG; Roach T; St John MA; Altfeld M; Marincola FM; Moore C; Mallal S; Carrington M; Heckerman D; Allen TM; Mullins JI; Korber BT; Goulder PJR; Walker BD; Brander C, 2006, 'Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes.', Nat Immunol, vol. 7, pp. 173 - 178, http://dx.doi.org/10.1038/ni1281
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Rousseau CM; Birditt BA; McKay AR; Stoddard JN; Lee TC; McLaughlin S; Moore SW; Shindo N; Learn GH; Korber BT; Brander C; Goulder PJR; Kiepiela P; Walker BD; Mullins JI, 2006, 'Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes.', J Virol Methods, vol. 136, pp. 118 - 125, http://dx.doi.org/10.1016/j.jviromet.2006.04.009
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Kaufmann SHE; Walker BD, 2006, 'Host-pathogen interactions.', Curr Opin Immunol, vol. 18, pp. 371 - 373, http://dx.doi.org/10.1016/j.coi.2006.05.009
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Draenert R; Allen TM; Liu Y; Wrin T; Chappey C; Verrill CL; Sirera G; Eldridge RL; Lahaie MP; Ruiz L; Clotet B; Petropoulos CJ; Walker BD; Martinez-Picado J, 2006, 'Constraints on HIV-1 evolution and immunodominance revealed in monozygotic adult twins infected with the same virus.', J Exp Med, vol. 203, pp. 529 - 539, http://dx.doi.org/10.1084/jem.20052116
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Komatsu H; Lauer G; Pybus OG; Ouchi K; Wong D; Ward S; Walker B; Klenerman P, 2006, 'Do antiviral CD8+ T cells select hepatitis C virus escape mutants? Analysis in diverse epitopes targeted by human intrahepatic CD8+ T lymphocytes.', J Viral Hepat, vol. 13, pp. 121 - 130, http://dx.doi.org/10.1111/j.1365-2893.2005.00676.x
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Zuñiga R; Lucchetti A; Galvan P; Sanchez S; Sanchez C; Hernandez A; Sanchez H; Frahm N; Linde CH; Hewitt HS; Hildebrand W; Altfeld M; Allen TM; Walker BD; Korber BT; Leitner T; Sanchez J; Brander C, 2006, 'Relative dominance of Gag p24-specific cytotoxic T lymphocytes is associated with human immunodeficiency virus control.', J Virol, vol. 80, pp. 3122 - 3125, http://dx.doi.org/10.1128/JVI.80.6.3122-3125.2006
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Kim AY; Schulze zur Wiesch J; Kuntzen T; Timm J; Kaufmann DE; Duncan JE; Jones AM; Wurcel AG; Davis BT; Gandhi RT; Robbins GK; Allen TM; Chung RT; Lauer GM; Walker BD, 2006, 'Impaired hepatitis C virus-specific T cell responses and recurrent hepatitis C virus in HIV coinfection.', PLoS Med, vol. 3, pp. e492, http://dx.doi.org/10.1371/journal.pmed.0030492
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Wherry EJ; Day CL; Draenert R; Miller JD; Kiepiela P; Woodberry T; Brander C; Addo M; Klenerman P; Ahmed R; Walker BD, 2006, 'HIV-specific CD8 T cells express low levels of IL-7Ralpha: implications for HIV-specific T cell memory.', Virology, vol. 353, pp. 366 - 373, http://dx.doi.org/10.1016/j.virol.2006.06.017
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Martinez-Hackert E; Anikeeva N; Kalams SA; Walker BD; Hendrickson WA; Sykulev Y, 2006, 'Structural basis for degenerate recognition of natural HIV peptide variants by cytotoxic lymphocytes.', J Biol Chem, vol. 281, pp. 20205 - 20212, http://dx.doi.org/10.1074/jbc.M601934200
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Martinez-Picado J; Prado JG; Fry EE; Pfafferott K; Leslie A; Chetty S; Thobakgale C; Honeyborne I; Crawford H; Matthews P; Pillay T; Rousseau C; Mullins JI; Brander C; Walker BD; Stuart DI; Kiepiela P; Goulder P, 2006, 'Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1.', J Virol, vol. 80, pp. 3617 - 3623, http://dx.doi.org/10.1128/JVI.80.7.3617-3623.2006
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Streeck H; Jessen H; Alter G; Teigen N; Waring MT; Jessen A; Stahmer I; van Lunzen J; Lichterfeld M; Gao X; Allen TM; Carrington M; Walker BD; Rockstroh JK; Altfeld M, 2006, 'Immunological and virological impact of highly active antiretroviral therapy initiated during acute HIV-1 infection.', J Infect Dis, vol. 194, pp. 734 - 739, http://dx.doi.org/10.1086/503811
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Meyer-Olson D; Brady KW; Bartman MT; O'Sullivan KM; Simons BC; Conrad JA; Duncan CB; Lorey S; Siddique A; Draenert R; Addo M; Altfeld M; Rosenberg E; Allen TM; Walker BD; Kalams SA, 2006, 'Fluctuations of functionally distinct CD8+ T-cell clonotypes demonstrate flexibility of the HIV-specific TCR repertoire.', Blood, vol. 107, pp. 2373 - 2383, http://dx.doi.org/10.1182/blood-2005-04-1636
    Journal articles | 2006
    Dr Bruce Duncan Walker
    McGovern BH; Wurcel A; Kim AY; Schulze zur Wiesch J; Bica I; Zaman MT; Timm J; Walker BD; Lauer GM, 2006, 'Acute hepatitis C virus infection in incarcerated injection drug users.', Clin Infect Dis, vol. 42, pp. 1663 - 1670, http://dx.doi.org/10.1086/504327
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Day CL; Kaufmann DE; Kiepiela P; Brown JA; Moodley ES; Reddy S; Mackey EW; Miller JD; Leslie AJ; DePierres C; Mncube Z; Duraiswamy J; Zhu B; Eichbaum Q; Altfeld M; Wherry EJ; Coovadia HM; Goulder PJR; Klenerman P; Ahmed R; Freeman GJ; Walker BD, 2006, 'PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.', Nature, vol. 443, pp. 350 - 354, http://dx.doi.org/10.1038/nature05115
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Vogel M; Lichterfeld M; Kaufmann DE; Mui SK; Altfeld M; Voigt E; Ahlenstiel G; Kupfer B; Walker B; Spengler U; Rockstroh JK, 2006, 'Structured treatment interruptions following immediate initiation of HAART in eight patients with acute HIV-1 seroconversion.', Eur J Med Res, vol. 11, pp. 273 - 278, https://www.ncbi.nlm.nih.gov/pubmed/16899420
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Leslie A; Price DA; Mkhize P; Bishop K; Rathod A; Day C; Crawford H; Honeyborne I; Asher TE; Luzzi G; Edwards A; Rousseau CM; Mullins JI; Tudor-Williams G; Novelli V; Brander C; Douek DC; Kiepiela P; Walker BD; Goulder PJR, 2006, 'Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype.', J Immunol, vol. 177, pp. 4699 - 4708, http://dx.doi.org/10.4049/jimmunol.177.7.4699
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Bihl F; Frahm N; Di Giammarino L; Sidney J; John M; Yusim K; Woodberry T; Sango K; Hewitt HS; Henry L; Linde CH; Chisholm JV; Zaman TM; Pae E; Mallal S; Walker BD; Sette A; Korber BT; Heckerman D; Brander C, 2006, 'Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses.', J Immunol, vol. 176, pp. 4094 - 4101, http://dx.doi.org/10.4049/jimmunol.176.7.4094
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Longworth S; Schulze zur Wiesch J; Kim AY; Kuntzen T; Timm J; Jones A; Chung RT; Allen TM; Walker BD; Lauer GM, 2006, 'O.187 Differential responsiveness of CD4 and CD8 T-cells during acute HCV re-infection', Journal of Clinical Virology, vol. 36, pp. S56 - S57, http://dx.doi.org/10.1016/s1386-6532(06)80172-1
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Timm J; Li B; Bhattacharya T; Daniels MG; Reyor LL; Allgaier R; Kuntzen T; Fischer W; Duncan J; Schulze zur Wiesch J; Kim A; Frahm N; Brander C; Chung RT; Lauer GM; Korber BT; Walker BD; Allen TM, 2006, 'P.191 HLA-associated sequence polymorphisms in HCV reveal the reproducibility of immune responses and constraints on viral evolution', Journal of Clinical Virology, vol. 36, pp. S119 - S120, http://dx.doi.org/10.1016/s1386-6532(06)80371-9
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Lichterfeld M; Williams KL; Mui SK; Shah SS; Mothe BR; Sette A; Kim A; Johnston MN; Burgett N; Frahm N; Cohen D; Brander C; Rosenberg ES; Walker BD; Altfeld M; Yu XG, 2006, 'T cell receptor cross-recognition of an HIV-1 CD8+ T cell epitope presented by closely related alleles from the HLA-A3 superfamily.', Int Immunol, vol. 18, pp. 1179 - 1188, http://dx.doi.org/10.1093/intimm/dxl052
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Brockman MA; Tanzi GO; Walker BD; Allen TM, 2006, 'Use of a novel GFP reporter cell line to examine replication capacity of CXCR4- and CCR5-tropic HIV-1 by flow cytometry.', J Virol Methods, vol. 131, pp. 134 - 142, http://dx.doi.org/10.1016/j.jviromet.2005.08.003
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Brander C; Frahm N; Walker BD, 2006, 'The challenges of host and viral diversity in HIV vaccine design.', Curr Opin Immunol, vol. 18, pp. 430 - 437, http://dx.doi.org/10.1016/j.coi.2006.05.012
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Kuntzen T; Lauer G; Timm J; Berical A; Schulze zur Wiesch J; Kim A; Lewis Ximenez L; Chung RT; Walker BD; Allen TM, 2006, 'P.163 Forces driving viral sequence evolution in acute hepatitis C infection', Journal of Clinical Virology, vol. 36, pp. S111 - S111, http://dx.doi.org/10.1016/s1386-6532(06)80343-4
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Nolan B; Kuntzen T; Jones A; Lewis-Ximenez L; Walker BD; Allen TM; Lauer GM, 2006, 'P.199 Dominant and subdominant T-cell responses and viral evolution in subjects with acute symptomatic HCV infection', Journal of Clinical Virology, vol. 36, pp. S122 - S122, http://dx.doi.org/10.1016/s1386-6532(06)80379-3
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Lewis-Ximenez LL; Espírito-Santo MP; Oliveira JM; Lauer G; Walker B; Yoshida CFT; Lampe E, 2006, 'P.297 Three cases of acute hepatitis C virus infection following dry sex', Journal of Clinical Virology, vol. 36, pp. S154 - S154, http://dx.doi.org/10.1016/s1386-6532(06)80476-2
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Honeyborne I; Rathod A; Buchli R; Ramduth D; Moodley E; Rathnavalu P; Chetty S; Day C; Brander C; Hildebrand W; Walker BD; Kiepiela P; Goulder PJR, 2006, 'Motif inference reveals optimal CTL epitopes presented by HLA class I alleles highly prevalent in southern Africa.', J Immunol, vol. 176, pp. 4699 - 4705, http://dx.doi.org/10.4049/jimmunol.176.8.4699
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Norris PJ; Stone JD; Anikeeva N; Heitman JW; Wilson IC; Hirschkorn DF; Clark MJ; Moffett HF; Cameron TO; Sykulev Y; Stern LJ; Walker BD, 2006, 'Antagonism of HIV-specific CD4+ T cells by C-terminal truncation of a minimum epitope.', Mol Immunol, vol. 43, pp. 1349 - 1357, http://dx.doi.org/10.1016/j.molimm.2005.09.004
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Wang S; Zhuang Y; Zhai S; Zhao S; Kang W; Li X; Yu XG; Walker BD; Altfeld MA; Sun Y, 2006, 'Association between HIV Type 1-specific T cell responses and CD4+ T cell counts or CD4+:CD8+ T cell ratios in HIV Type 1 subtype B infection in China.', AIDS Res Hum Retroviruses, vol. 22, pp. 780 - 787, http://dx.doi.org/10.1089/aid.2006.22.780
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Gasser O; Bihl FK; Loggi E; Steffen I; Hirsch HH; Günthard HF; Walker BD; Brander C; Battegay M; Hess C, 2006, '63 Epstein-Barr Virus-selective immuno-deficiency in HIV-infected individuals developing primary central nervous system lymphoma', International Journal of Infectious Diseases, vol. 10, pp. S34 - S34, http://dx.doi.org/10.1016/s1201-9712(06)80060-3
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Pereyra F; Addo MM; Kaufmann DE; Miura T; Rathod A; Baker B; Trocha A; Ueda P; Rosenberg R; Cohen D; Stone D; Liu Y; Wrin T; Buchbinder S; Petropoulos CJ; Rosenberg E; Walker BD, 2006, '', Retrovirology, vol. 3, pp. S16 - S16, http://dx.doi.org/10.1186/1742-4690-3-s1-s16
    Journal articles | 2006
    Dr Bruce Duncan Walker
    Leslie A; Price DA; Mkhize P; Bishop K; Rathod A; Day C; Crawford H; Honeyborne I; Asher TE; Luzzi G; Edwards A; Rosseau CM; Mullins JI; Tudor-Williams G; Novelli V; Brander C; Douek DC; Kiepiela P; Walker BD; Goulder PJR, 2006, 'Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype', The Journal of Immunology, vol. 177, pp. 8878.2 - 8878, http://dx.doi.org/10.4049/jimmunol.177.12.8878-a
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Lauer GM; Lucas M; Timm J; Ouchi K; Kim AY; Day CL; Schulze Zur Wiesch J; Paranhos-Baccala G; Sheridan I; Casson DR; Reiser M; Gandhi RT; Li B; Allen TM; Chung RT; Klenerman P; Walker BD, 2005, 'Full-breadth analysis of CD8+ T-cell responses in acute hepatitis C virus infection and early therapy.', J Virol, vol. 79, pp. 12979 - 12988, http://dx.doi.org/10.1128/JVI.79.20.12979-12988.2005
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Woodberry T; Suscovich TJ; Henry LM; Martin JN; Dollard S; O'Connor PG; Davis JK; Osmond D; Lee T-H; Kedes DH; Khatri A; Lee J; Walker BD; Scadden DT; Brander C, 2005, 'Impact of Kaposi sarcoma-associated herpesvirus (KSHV) burden and HIV coinfection on the detection of T cell responses to KSHV ORF73 and ORF65 proteins.', J Infect Dis, vol. 192, pp. 622 - 629, http://dx.doi.org/10.1086/432103
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Rodriguez WR; Christodoulides N; Floriano PN; Graham S; Mohanty S; Dixon M; Hsiang M; Peter T; Zavahir S; Thior I; Romanovicz D; Bernard B; Goodey AP; Walker BD; McDevitt JT, 2005, 'A microchip CD4 counting method for HIV monitoring in resource-poor settings.', PLoS Med, vol. 2, pp. e182, http://dx.doi.org/10.1371/journal.pmed.0020182
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Yu XG; Lichterfeld M; Perkins B; Kalife E; Mui S; Chen J; Cheng M; Kang W; Alter G; Brander C; Walker BD; Altfeld M, 2005, 'High degree of inter-clade cross-reactivity of HIV-1-specific T cell responses at the single peptide level.', AIDS, vol. 19, pp. 1449 - 1456, http://dx.doi.org/10.1097/01.aids.0000183126.32077.c8
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Altfeld M; Allen TM; Kalife ET; Frahm N; Addo MM; Mothe BR; Rathod A; Reyor LL; Harlow J; Yu XG; Perkins B; Robinson LK; Sidney J; Alter G; Lichterfeld M; Sette A; Rosenberg ES; Goulder PJR; Brander C; Walker BD, 2005, 'The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design.', J Virol, vol. 79, pp. 5000 - 5005, http://dx.doi.org/10.1128/JVI.79.8.5000-5005.2005
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Frahm N; Adams S; Kiepiela P; Linde CH; Hewitt HS; Lichterfeld M; Sango K; Brown NV; Pae E; Wurcel AG; Altfeld M; Feeney ME; Allen TM; Roach T; St John MA; Daar ES; Rosenberg E; Korber B; Marincola F; Walker BD; Goulder PJR; Brander C, 2005, 'HLA-B63 presents HLA-B57/B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load.', J Virol, vol. 79, pp. 10218 - 10225, http://dx.doi.org/10.1128/JVI.79.16.10218-10225.2005
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Koibuchi T; Allen TM; Lichterfeld M; Mui SK; O'Sullivan KM; Trocha A; Kalams SA; Johnson RP; Walker BD, 2005, 'Limited sequence evolution within persistently targeted CD8 epitopes in chronic human immunodeficiency virus type 1 infection.', J Virol, vol. 79, pp. 8171 - 8181, http://dx.doi.org/10.1128/JVI.79.13.8171-8181.2005
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Allen TM; Yu XG; Kalife ET; Reyor LL; Lichterfeld M; John M; Cheng M; Allgaier RL; Mui S; Frahm N; Alter G; Brown NV; Johnston MN; Rosenberg ES; Mallal SA; Brander C; Walker BD; Altfeld M, 2005, 'De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection.', J Virol, vol. 79, pp. 12952 - 12960, http://dx.doi.org/10.1128/JVI.79.20.12952-12960.2005
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Allen TM; Altfeld M; Geer SC; Kalife ET; Moore C; O'sullivan KM; Desouza I; Feeney ME; Eldridge RL; Maier EL; Kaufmann DE; Lahaie MP; Reyor L; Tanzi G; Johnston MN; Brander C; Draenert R; Rockstroh JK; Jessen H; Rosenberg ES; Mallal SA; Walker BD, 2005, 'Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution.', J Virol, vol. 79, pp. 13239 - 13249, http://dx.doi.org/10.1128/JVI.79.21.13239-13249.2005
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Woodberry T; Suscovich TJ; Henry LM; Davis JK; Frahm N; Walker BD; Scadden DT; Wang F; Brander C, 2005, 'Differential targeting and shifts in the immunodominance of Epstein-Barr virus--specific CD8 and CD4 T cell responses during acute and persistent infection.', J Infect Dis, vol. 192, pp. 1513 - 1524, http://dx.doi.org/10.1086/491741
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Ramduth D; Chetty P; Mngquandaniso NC; Nene N; Harlow JD; Honeyborne I; Ntumba N; Gappoo S; Henry C; Jeena P; Addo MM; Altfeld M; Brander C; Day C; Coovadia H; Kiepiela P; Goulder P; Walker B, 2005, 'Differential immunogenicity of HIV-1 clade C proteins in eliciting CD8+ and CD4+ cell responses.', J Infect Dis, vol. 192, pp. 1588 - 1596, http://dx.doi.org/10.1086/496894
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Sumida SM; Truitt DM; Lemckert AAC; Vogels R; Custers JHHV; Addo MM; Lockman S; Peter T; Peyerl FW; Kishko MG; Jackson SS; Gorgone DA; Lifton MA; Essex M; Walker BD; Goudsmit J; Havenga MJE; Barouch DH, 2005, 'Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein.', J Immunol, vol. 174, pp. 7179 - 7185, http://dx.doi.org/10.4049/jimmunol.174.11.7179
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Schulze zur Wiesch J; Lauer GM; Day CL; Kim AY; Ouchi K; Duncan JE; Wurcel AG; Timm J; Jones AM; Mothe B; Allen TM; McGovern B; Lewis-Ximenez L; Sidney J; Sette A; Chung RT; Walker BD, 2005, 'Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes.', J Immunol, vol. 175, pp. 3603 - 3613, http://dx.doi.org/10.4049/jimmunol.175.6.3603
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Feeney ME; Tang Y; Pfafferott K; Roosevelt KA; Draenert R; Trocha A; Yu XG; Verrill C; Allen T; Moore C; Mallal S; Burchett S; McIntosh K; Pelton SI; St John MA; Hazra R; Klenerman P; Altfeld M; Walker BD; Goulder PJR, 2005, 'HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response.', J Immunol, vol. 174, pp. 7524 - 7530, http://dx.doi.org/10.4049/jimmunol.174.12.7524
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Zaunders J; Munier M; Kaufmann D; Ip S; Grey PA; Smith DE; Ramacciotti TP; Quan D; Finlayson RJ; Kaldor JM; Rosenberg E; Walker BD; Cooper DA; Kelleher AD, 2005, 'Early proliferation of CCR5(+) CD38(+++) antigen-specific CD4(+) Th1 effector cells during primary HIV-1 infection', Blood, vol. 106, pp. 1660 - 1667, http://dx.doi.org/10.1182/blood-2005-01-0206
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Kim AY; Lauer GM; Ouchi K; Addo MM; Lucas M; Schulze Zur Wiesch J; Timm J; Boczanowski M; Duncan JE; Wurcel AG; Casson D; Chung RT; Draenert R; Klenerman P; Walker BD, 2005, 'The magnitude and breadth of hepatitis C virus-specific CD8+ T cells depend on absolute CD4+ T-cell count in individuals coinfected with HIV-1.', Blood, vol. 105, pp. 1170 - 1178, http://dx.doi.org/10.1182/blood-2004-06-2336
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Walker BD; Krahn AD; Klein GJ; Skanes AC; Yee R; Wang J; Hegele RA, 2005, 'Effect of change in posture and exercise on repolarization in patients with long QT syndrome with HERG channel mutations', Canadian Journal of Cardiology, vol. 21, pp. 33 - 38
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Walker BD; Krahn AD; Klein GJ; Skanes AC; Yee R, 2005, 'Burst bicycle exercise facilitates diagnosis of latent long QT syndrome', American Heart Journal, vol. 150, pp. 1059 - 1063, http://dx.doi.org/10.1016/j.ahj.2005.02.041
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Krahn AD; Gollob M; Yee R; Gula LJ; Skanes AC; Walker BD; Klein GJ, 2005, 'Diagnosis of unexplained cardiac arrest: Role of adrenaline and procainamide infusion', Circulation, vol. 112, pp. 2228 - 2234, http://dx.doi.org/10.1161/CIRCULATIONAHA.105.552166
    Journal articles | 2005
    Dr Bruce Duncan Walker
    Timm J; Reiser M; Brechmann T; Reyor L; Schmiegel W; Walker B; Allen T, 2005, 'HLA-A1 assoziierter Selektionsdruck beeinflusst die Evolution des Hepatitis C Virus', Zeitschrift für Gastroenterologie, vol. 43, http://dx.doi.org/10.1055/s-2005-920074
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Allen TM; Altfeld M; Yu XG; O'Sullivan KM; Lichterfeld M; Le Gall S; John M; Mothe BR; Lee PK; Kalife ET; Cohen DE; Freedberg KA; Strick DA; Johnston MN; Sette A; Rosenberg ES; Mallal SA; Goulder PJR; Brander C; Walker BD, 2004, 'Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection.', J Virol, vol. 78, pp. 7069 - 7078, http://dx.doi.org/10.1128/JVI.78.13.7069-7078.2004
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Hess C; Means TK; Autissier P; Woodberry T; Altfeld M; Addo MM; Frahm N; Brander C; Walker BD; Luster AD, 2004, 'IL-8 responsiveness defines a subset of CD8 T cells poised to kill.', Blood, vol. 104, pp. 3463 - 3471, http://dx.doi.org/10.1182/blood-2004-03-1067
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Kaufmann DE; Lichterfeld M; Altfeld M; Addo MM; Johnston MN; Lee PK; Wagner BS; Kalife ET; Strick D; Rosenberg ES; Walker BD, 2004, 'Limited durability of viral control following treated acute HIV infection.', PLoS Med, vol. 1, pp. e36, http://dx.doi.org/10.1371/journal.pmed.0010036
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Lichterfeld M; Kaufmann DE; Yu XG; Mui SK; Addo MM; Johnston MN; Cohen D; Robbins GK; Pae E; Alter G; Wurcel A; Stone D; Rosenberg ES; Walker BD; Altfeld M, 2004, 'Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells.', J Exp Med, vol. 200, pp. 701 - 712, http://dx.doi.org/10.1084/jem.20041270
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Kaufmann DE; Bailey PM; Sidney J; Wagner B; Norris PJ; Johnston MN; Cosimi LA; Addo MM; Lichterfeld M; Altfeld M; Frahm N; Brander C; Sette A; Walker BD; Rosenberg ES, 2004, 'Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides.', J Virol, vol. 78, pp. 4463 - 4477, http://dx.doi.org/10.1128/jvi.78.9.4463-4477.2004
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Brainard DM; Tharp WG; Granado E; Miller N; Trocha AK; Ren X-H; Conrad B; Terwilliger EF; Wyatt R; Walker BD; Poznansky MC, 2004, 'Migration of antigen-specific T cells away from CXCR4-binding human immunodeficiency virus type 1 gp120.', J Virol, vol. 78, pp. 5184 - 5193, http://dx.doi.org/10.1128/jvi.78.10.5184-5193.2004
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Timm J; Lauer GM; Kavanagh DG; Sheridan I; Kim AY; Lucas M; Pillay T; Ouchi K; Reyor LL; Schulze zur Wiesch J; Gandhi RT; Chung RT; Bhardwaj N; Klenerman P; Walker BD; Allen TM, 2004, 'CD8 epitope escape and reversion in acute HCV infection.', J Exp Med, vol. 200, pp. 1593 - 1604, http://dx.doi.org/10.1084/jem.20041006
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Lauer GM; Barnes E; Lucas M; Timm J; Ouchi K; Kim AY; Day CL; Robbins GK; Casson DR; Reiser M; Dusheiko G; Allen TM; Chung RT; Walker BD; Klenerman P, 2004, 'High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection.', Gastroenterology, vol. 127, pp. 924 - 936, http://dx.doi.org/10.1053/j.gastro.2004.06.015
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Draenert R; Le Gall S; Pfafferott KJ; Leslie AJ; Chetty P; Brander C; Holmes EC; Chang S-C; Feeney ME; Addo MM; Ruiz L; Ramduth D; Jeena P; Altfeld M; Thomas S; Tang Y; Verrill CL; Dixon C; Prado JG; Kiepiela P; Martinez-Picado J; Walker BD; Goulder PJR, 2004, 'Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection.', J Exp Med, vol. 199, pp. 905 - 915, http://dx.doi.org/10.1084/jem.20031982
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Draenert R; Verrill CL; Tang Y; Allen TM; Wurcel AG; Boczanowski M; Lechner A; Kim AY; Suscovich T; Brown NV; Addo MM; Walker BD, 2004, 'Persistent recognition of autologous virus by high-avidity CD8 T cells in chronic, progressive human immunodeficiency virus type 1 infection.', J Virol, vol. 78, pp. 630 - 641, http://dx.doi.org/10.1128/jvi.78.2.630-641.2004
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Kiepiela P; Leslie AJ; Honeyborne I; Ramduth D; Thobakgale C; Chetty S; Rathnavalu P; Moore C; Pfafferott KJ; Hilton L; Zimbwa P; Moore S; Allen T; Brander C; Addo MM; Altfeld M; James I; Mallal S; Bunce M; Barber LD; Szinger J; Day C; Klenerman P; Mullins J; Korber B; Coovadia HM; Walker BD; Goulder PJR, 2004, 'Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.', Nature, vol. 432, pp. 769 - 775, http://dx.doi.org/10.1038/nature03113
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Feeney ME; Tang Y; Roosevelt KA; Leslie AJ; McIntosh K; Karthas N; Walker BD; Goulder PJR, 2004, 'Immune escape precedes breakthrough human immunodeficiency virus type 1 viremia and broadening of the cytotoxic T-lymphocyte response in an HLA-B27-positive long-term-nonprogressing child.', J Virol, vol. 78, pp. 8927 - 8930, http://dx.doi.org/10.1128/JVI.78.16.8927-8930.2004
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Zavala-Ruiz Z; Strug I; Walker BD; Norris PJ; Stern LJ, 2004, 'A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition.', Proc Natl Acad Sci U S A, vol. 101, pp. 13279 - 13284, http://dx.doi.org/10.1073/pnas.0403371101
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Lichterfeld M; Yu XG; Waring M; Mui S; Johnston M; Cohen D; Addo M; Zaunders J; Alter G; Pae E; Strick D; Allen TM; Rosenberg E; Walker BD; Altfeld M, 2004, 'HIV-1-specific cytotoxicity is preferentially mediated by a subset ofCD8(+) T cells producing both interferon-gamma and tumor necrosisfactor-alpha', Blood, vol. 104, pp. 487 - 494, http://dx.doi.org/10.1182/blood-2003-12-4341
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Draenert R; Brander C; Yu XG; Altfeld M; Verrill CL; Feeney ME; Walker BD; Goulder PJR, 2004, 'Impact of intrapeptide epitope location on CD8 T cell recognition: implications for design of overlapping peptide panels.', AIDS, vol. 18, pp. 871 - 876, http://dx.doi.org/10.1097/00002030-200404090-00004
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Hess C; Altfeld M; Thomas SY; Addo MM; Rosenberg ES; Allen TM; Draenert R; Eldrige RL; van Lunzen J; Stellbrink H-J; Walker BD; Luster AD, 2004, 'HIV-1 specific CD8+ T cells with an effector phenotype and control of viral replication.', Lancet, vol. 363, pp. 863 - 866, http://dx.doi.org/10.1016/S0140-6736(04)15735-8
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Lichterfeld M; Yu XG; Cohen D; Addo MM; Malenfant J; Perkins B; Pae E; Johnston MN; Strick D; Allen TM; Rosenberg ES; Korber B; Walker BD; Altfeld M, 2004, 'HIV-1 Nef is preferentially recognized by CD8 T cells in primary HIV-1 infection despite a relatively high degree of genetic diversity.', AIDS, vol. 18, pp. 1383 - 1392, http://dx.doi.org/10.1097/01.aids.0000131329.51633.a3
    Journal articles | 2004
    Dr Bruce Duncan Walker
    SenGupta D; Norris PJ; Suscovich TJ; Hassan-Zahraee M; Moffett HF; Trocha A; Draenert R; Goulder PJR; Binder RJ; Levey DL; Walker BD; Srivastava PK; Brander C, 2004, 'Heat shock protein-mediated cross-presentation of exogenous HIV antigen on HLA class I and class II.', J Immunol, vol. 173, pp. 1987 - 1993, http://dx.doi.org/10.4049/jimmunol.173.3.1987
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Rodriguez WR; Addo MM; Rathod A; Fitzpatrick CA; Yu XG; Perkins B; Rosenberg ES; Altfeld M; Walker BD, 2004, 'CD8+ T lymphocyte responses target functionally important regions of Protease and Integrase in HIV-1 infected subjects.', J Transl Med, vol. 2, pp. 15, http://dx.doi.org/10.1186/1479-5876-2-15
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Lebedeva T; Anikeeva N; Kalams SA; Walker BD; Gaidarov I; Keen JH; Sykulev Y, 2004, 'Major histocompatibility complex class I-intercellular adhesion molecule-1 association on the surface of target cells: implications for antigen presentation to cytotoxic T lymphocytes.', Immunology, vol. 113, pp. 460 - 471, http://dx.doi.org/10.1111/j.1365-2567.2004.01985.x
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Deeks SG; Walker BD, 2004, 'The immune response to AIDS virus infection: good, bad, or both?', J Clin Invest, vol. 113, pp. 808 - 810, http://dx.doi.org/10.1172/JCI21318
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Norris PJ; Moffett HF; Brander C; Allen TM; O'Sullivan KM; Cosimi LA; Kaufmann DE; Walker BD; Rosenberg ES, 2004, 'Fine specificity and cross-clade reactivity of HIV type 1 Gag-specific CD4+ T cells.', AIDS Res Hum Retroviruses, vol. 20, pp. 315 - 325, http://dx.doi.org/10.1089/088922204322996554
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Suscovich TJ; Paulose-Murphy M; Harlow JD; Chen Y; Thomas SY; Mellott TJ; Walker BD; Scadden DT; Zeichner S; Brander C, 2004, 'Defective immune function of primary effusion lymphoma cells is associated with distinct KSHV gene expression profiles.', Leuk Lymphoma, vol. 45, pp. 1223 - 1238, http://dx.doi.org/10.1080/10428190310001643358
    Journal articles | 2004
    Dr Bruce Duncan Walker
    Yu XG; Addo MM; Perkins BA; Wej F; Rathod A; Geer SC; Parta M; Cohen D; Stone DR; Russell CJ; Tanzi G; Mei S; Wurcel AG; Frahm N; Lichterfeld M; Heath L; Mullins JI; Marincola F; Goulder PJR; Brander C; Allen T; Cao Y; Walker BD; Altfeld M, 2004, 'Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians.', AIDS Res Hum Retroviruses, vol. 20, pp. 557 - 564, http://dx.doi.org/10.1089/088922204323087813
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Somsouk M; Lauer GM; Casson D; Terella A; Day CL; Walker BD; Chung RT, 2003, 'Spontaneous resolution of chronic hepatitis C virus disease after withdrawal of immunosuppression.', Gastroenterology, vol. 124, pp. 1946 - 1949, http://dx.doi.org/10.1016/s0016-5085(03)00391-3
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Severino ME; Sarkis PTN; Walker BD; Yang OO, 2003, 'Chimeric immune receptor T cells bypass class I requirements and recognize multiple cell types relevant in HIV-1 infection.', Virology, vol. 306, pp. 371 - 375, http://dx.doi.org/10.1016/s0042-6822(02)00055-7
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Delgado JC; Leung JY; Baena A; Clavijo OP; Vittinghoff E; Buchbinder S; Wolinsky S; Addo M; Walker BD; Yunis EJ; Goldfeld AE, 2003, 'The -1030/-862-linked TNF promoter single-nucleotide polymorphisms are associated with the inability to control HIV-1 viremia.', Immunogenetics, vol. 55, pp. 497 - 501, http://dx.doi.org/10.1007/s00251-003-0604-7
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Geiben-Lynn R; Kursar M; Brown NV; Addo MM; Shau H; Lieberman J; Luster AD; Walker BD, 2003, 'HIV-1 antiviral activity of recombinant natural killer cell enhancing factors, NKEF-A and NKEF-B, members of the peroxiredoxin family.', J Biol Chem, vol. 278, pp. 1569 - 1574, http://dx.doi.org/10.1074/jbc.M209964200
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Gandhi RT; Wurcel A; Rosenberg ES; Johnston MN; Hellmann N; Bates M; Hirsch MS; Walker BD, 2003, 'Progressive reversion of human immunodeficiency virus type 1 resistance mutations in vivo after transmission of a multiply drug-resistant virus.', Clin Infect Dis, vol. 37, pp. 1693 - 1698, http://dx.doi.org/10.1086/379773
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Altfeld M; Addo MM; Shankarappa R; Lee PK; Allen TM; Yu XG; Rathod A; Harlow J; O'Sullivan K; Johnston MN; Goulder PJR; Mullins JI; Rosenberg ES; Brander C; Korber B; Walker BD, 2003, 'Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences.', J Virol, vol. 77, pp. 7330 - 7340, http://dx.doi.org/10.1128/jvi.77.13.7330-7340.2003
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Robbins GK; Addo MM; Troung H; Rathod A; Habeeb K; Davis B; Heller H; Basgoz N; Walker BD; Rosenberg ES, 2003, 'Augmentation of HIV-1-specific T helper cell responses in chronic HIV-1 infection by therapeutic immunization.', AIDS, vol. 17, pp. 1121 - 1126, http://dx.doi.org/10.1097/00002030-200305230-00002
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Brander C; Walker BD, 2003, 'Gradual adaptation of HIV to human host populations: good or bad news?', Nat Med, vol. 9, pp. 1359 - 1362, http://dx.doi.org/10.1038/nm941
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Yang OO; Sarkis PTN; Ali A; Harlow JD; Brander C; Kalams SA; Walker BD, 2003, 'Determinant of HIV-1 mutational escape from cytotoxic T lymphocytes.', J Exp Med, vol. 197, pp. 1365 - 1375, http://dx.doi.org/10.1084/jem.20022138
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Draenert R; Altfeld M; Brander C; Basgoz N; Corcoran C; Wurcel AG; Stone DR; Kalams SA; Trocha A; Addo MM; Goulder PJR; Walker BD, 2003, 'Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses.', J Immunol Methods, vol. 275, pp. 19 - 29, http://dx.doi.org/10.1016/s0022-1759(02)00541-0
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Feeney ME; Roosevelt KA; Tang Y; Pfafferott KJ; McIntosh K; Burchett SK; Mao C; Walker BD; Goulder PJR, 2003, 'Comprehensive screening reveals strong and broadly directed human immunodeficiency virus type 1-specific CD8 responses in perinatally infected children.', J Virol, vol. 77, pp. 7492 - 7501, http://dx.doi.org/10.1128/jvi.77.13.7492-7501.2003
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Day CL; Seth NP; Lucas M; Appel H; Gauthier L; Lauer GM; Robbins GK; Szczepiorkowski ZM; Casson DR; Chung RT; Bell S; Harcourt G; Walker BD; Klenerman P; Wucherpfennig KW, 2003, 'Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers.', J Clin Invest, vol. 112, pp. 831 - 842, http://dx.doi.org/10.1172/JCI18509
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Tremblay CL; Hicks JL; Sutton L; Giguel F; Flynn T; Johnston M; Sax PE; Walker BD; Hirsch MS; Rosenberg ES; D'Aquila RT, 2003, 'Antiretroviral resistance associated with supervised treatment interruptions in treated acute HIV infection.', AIDS, vol. 17, pp. 1086 - 1089, http://dx.doi.org/10.1097/00002030-200305020-00021
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Addo MM; Yu XG; Rathod A; Cohen D; Eldridge RL; Strick D; Johnston MN; Corcoran C; Wurcel AG; Fitzpatrick CA; Feeney ME; Rodriguez WR; Basgoz N; Draenert R; Stone DR; Brander C; Goulder PJR; Rosenberg ES; Altfeld M; Walker BD, 2003, 'Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.', J Virol, vol. 77, pp. 2081 - 2092, http://dx.doi.org/10.1128/jvi.77.3.2081-2092.2003
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Feeney ME; Draenert R; Roosevelt KA; Pelton SI; McIntosh K; Burchett SK; Mao C; Walker BD; Goulder PJR, 2003, 'Reconstitution of virus-specific CD4 proliferative responses in pediatric HIV-1 infection.', J Immunol, vol. 171, pp. 6968 - 6975, http://dx.doi.org/10.4049/jimmunol.171.12.6968
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Yang OO; Sarkis PTN; Trocha A; Kalams SA; Johnson RP; Walker BD, 2003, 'Impacts of avidity and specificity on the antiviral efficiency of HIV-1-specific CTL.', J Immunol, vol. 171, pp. 3718 - 3724, http://dx.doi.org/10.4049/jimmunol.171.7.3718
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Montefiori DC; Altfeld M; Lee PK; Bilska M; Zhou J; Johnston MN; Gao F; Walker BD; Rosenberg ES, 2003, 'Viremia control despite escape from a rapid and potent autologous neutralizing antibody response after therapy cessation in an HIV-1-infected individual.', J Immunol, vol. 170, pp. 3906 - 3914, http://dx.doi.org/10.4049/jimmunol.170.7.3906
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Cao H; Kaleebu P; Hom D; Flores J; Agrawal D; Jones N; Serwanga J; Okello M; Walker C; Sheppard H; El-Habib R; Klein M; Mbidde E; Mugyenyi P; Walker B; Ellner J; Mugerwa R; HIV Network for Prevention Trials , 2003, 'Immunogenicity of a recombinant human immunodeficiency virus (HIV)-canarypox vaccine in HIV-seronegative Ugandan volunteers: results of the HIV Network for Prevention Trials 007 Vaccine Study.', J Infect Dis, vol. 187, pp. 887 - 895, http://dx.doi.org/10.1086/368020
    Journal articles | 2003
    Dr Bruce Duncan Walker
    LAUER G; LUCAS M; OUCHI K; KIM A; DAY C; CASSON D; SHERIDAN I; LAVENDER B; GANDHI R; REISER M, 2003, '403 T-cell responses during early therapy for HCV infection', Hepatology, vol. 38, pp. 354 - 355, http://dx.doi.org/10.1016/s0270-9139(03)80446-9
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Letvin NL; Walker BD, 2003, 'Immunopathogenesis and immunotherapy in AIDS virus infections.', Nat Med, vol. 9, pp. 861 - 866, http://dx.doi.org/10.1038/nm0703-861
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Autran B; Debré P; Walker B; Katlama C, 2003, 'Therapeutic vaccines against HIV need international partnerships.', Nat Rev Immunol, vol. 3, pp. 503 - 508, http://dx.doi.org/10.1038/nri1107
    Journal articles | 2003
    Dr Bruce Duncan Walker
    TIMM J; LAUER G; LEWISXIMENEZ L; OUCHI K; KIM A; WALKER B; ALLEN T, 2003, '400 Longitudinal full genome sequencing to assess the extent of CD8+ CTL escape in HCV', Hepatology, vol. 38, pp. 352 - 353, http://dx.doi.org/10.1016/s0270-9139(03)80443-3
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Altfeld M; Addo MM; Rosenberg ES; Hecht FM; Lee PK; Vogel M; Yu XG; Draenert R; Johnston MN; Strick D; Allen TM; Feeney ME; Kahn JO; Sekaly RP; Levy JA; Rockstroh JK; Goulder PJ; Walker BD, 2003, 'Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection.', AIDS, vol. 17, pp. 2581 - 2591, http://dx.doi.org/10.1097/00002030-200312050-00005
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Bhardwaj N; Walker BD, 2003, 'Immunotherapy for AIDS virus infections: cautious optimism for cell-based vaccine.', Nat Med, vol. 9, pp. 13 - 14, http://dx.doi.org/10.1038/nm0103-13
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Bobbitt KR; Addo MM; Altfeld M; Filzen T; Onafuwa AA; Walker BD; Collins KL, 2003, 'Rev activity determines sensitivity of HIV-1-infected primary T cells to CTL killing.', Immunity, vol. 18, pp. 289 - 299, http://dx.doi.org/10.1016/s1074-7613(03)00031-1
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Walker BD; Krahn AD; Klein GJ; Skanes AC; Wang J; Hegele RA; Yee R, 2003, 'Congenital and acquired long QT syndromes', Canadian Journal of Cardiology, vol. 19, pp. 76 - 87
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Day CL; Walker BD, 2003, 'Progress in defining CD4 helper cell responses in chronic viral infections.', J Exp Med, vol. 198, pp. 1773 - 1777, http://dx.doi.org/10.1084/jem.20031947
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Altfeld M; Allen TM; Yu XG; Johnston MN; Agrawal D; Korber BT; Montefiori DC; O'Connor DH; Davis BT; Lee PK; Maier EL; Harlow J; Goulder PJR; Brander C; Rosenberg ES; Walker BD, 2003, 'addendum: HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus', Nature, vol. 423, pp. 461 - 461, http://dx.doi.org/10.1038/nature01662
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Walker BD; Krahn AD; Klein GJ; Skanes AC; Yee R, 2003, 'Drug induced QT prolongation: Lessons from congenital and acquired long QT syndromes', Current Drug Targets - Cardiovascular and Haematological Disorders, vol. 3, pp. 327 - 335, http://dx.doi.org/10.2174/1568006033481393
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Kuchar DL; Walker BD; Thorburn CW, 2003, 'In reply: Ventricular tachycardia following ingestion of a commonly used antihistamine', Medical Journal of Australia, vol. 178, pp. 244 - 246, http://dx.doi.org/10.5694/j.1326-5377.2003.tb05177.x
    Journal articles | 2003
    Dr Bruce Duncan Walker
    Sager PT; Veltri EP; Kuchar DL; Walker BD; Thorburn CW, 2003, 'Ventricular tachycardia following ingestion of a commonly used antihistamine (multiple letters)', Medical Journal of Australia, vol. 178, pp. 245 - 246
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Lauer GM; Ouchi K; Chung RT; Nguyen TN; Day CL; Purkis DR; Reiser M; Kim AY; Lucas M; Klenerman P; Walker BD, 2002, 'Comprehensive analysis of CD8(+)-T-cell responses against hepatitis C virus reveals multiple unpredicted specificities.', J Virol, vol. 76, pp. 6104 - 6113, http://dx.doi.org/10.1128/jvi.76.12.6104-6113.2002
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Yu XG; Addo MM; Rosenberg ES; Rodriguez WR; Lee PK; Fitzpatrick CA; Johnston MN; Strick D; Goulder PJR; Walker BD; Altfeld M, 2002, 'Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infection.', J Virol, vol. 76, pp. 8690 - 8701, http://dx.doi.org/10.1128/jvi.76.17.8690-8701.2002
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Brander C; Raje N; O'Connor PG; Davies F; Davis J; Chauhan D; Hideshima T; Martin J; Osmond D; Kedes DH; Walker BD; Scadden DT; Anderson KC, 2002, 'Absence of biologically important Kaposi sarcoma-associated herpesvirus gene products and virus-specific cellular immune responses in multiple myeloma.', Blood, vol. 100, pp. 698 - 700, http://dx.doi.org/10.1182/blood.v100.2.698
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Day CL; Lauer GM; Robbins GK; McGovern B; Wurcel AG; Gandhi RT; Chung RT; Walker BD, 2002, 'Broad specificity of virus-specific CD4+ T-helper-cell responses in resolved hepatitis C virus infection.', J Virol, vol. 76, pp. 12584 - 12595, http://dx.doi.org/10.1128/jvi.76.24.12584-12595.2002
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Lauer GM; Nguyen TN; Day CL; Robbins GK; Flynn T; McGowan K; Rosenberg ES; Lucas M; Klenerman P; Chung RT; Walker BD, 2002, 'Human immunodeficiency virus type 1-hepatitis C virus coinfection: intraindividual comparison of cellular immune responses against two persistent viruses.', J Virol, vol. 76, pp. 2817 - 2826, http://dx.doi.org/10.1128/jvi.76.6.2817-2826.2002
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Yang OO; Nguyen PT; Kalams SA; Dorfman T; Göttlinger HG; Stewart S; Chen ISY; Threlkeld S; Walker BD, 2002, 'Nef-mediated resistance of human immunodeficiency virus type 1 to antiviral cytotoxic T lymphocytes.', J Virol, vol. 76, pp. 1626 - 1631, http://dx.doi.org/10.1128/jvi.76.4.1626-1631.2002
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Altfeld M; Allen TM; Yu XG; Johnston MN; Agrawal D; Korber BT; Montefiori DC; O'Connor DH; Davis BT; Lee PK; Maier EL; Harlow J; Goulder PJR; Brander C; Rosenberg ES; Walker BD, 2002, 'HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus.', Nature, vol. 420, pp. 434 - 439, http://dx.doi.org/10.1038/nature01200
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Altfeld M; van Lunzen J; Frahm N; Yu XG; Schneider C; Eldridge RL; Feeney ME; Meyer-Olson D; Stellbrink H-J; Walker BD, 2002, 'Expansion of pre-existing, lymph node-localized CD8+ T cells during supervised treatment interruptions in chronic HIV-1 infection.', J Clin Invest, vol. 109, pp. 837 - 843, http://dx.doi.org/10.1172/JCI14789
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Barnes E; Lauer G; Walker B; Klenerman P, 2002, 'T cell failure in hepatitis C virus infection.', Viral Immunol, vol. 15, pp. 285 - 293, http://dx.doi.org/10.1089/08828240260066233
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Chauhan VS; Krahn AD; Walker BD; Klein GJ; Skanes AC; Yee R, 2002, 'Sex differences in QTc interval and QT dispersion: Dynamics during exercise and recovery in healthy subjects', American Heart Journal, vol. 144, pp. 858 - 864, http://dx.doi.org/10.1016/S0002-8703(02)80021-7
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Ward S; Lauer G; Isba R; Walker B; Klenerman P, 2002, 'Cellular immune responses against hepatitis C virus: the evidence base 2002.', Clin Exp Immunol, vol. 128, pp. 195 - 203, http://dx.doi.org/10.1046/j.1365-2249.2002.01840.x
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Geiben-Lynn R; Brown N; Walker BD; Luster AD, 2002, 'Purification of a modified form of bovine antithrombin III as an HIV-1 CD8+ T-cell antiviral factor.', J Biol Chem, vol. 277, pp. 42352 - 42357, http://dx.doi.org/10.1074/jbc.M207079200
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Yang OO; Garcia-Zepeda EA; Walker BD; Luster AD, 2002, 'Monocyte chemoattractant protein-2 (CC chemokine ligand 8) inhibits replication of human immunodeficiency virus type 1 via CC chemokine receptor 5.', J Infect Dis, vol. 185, pp. 1174 - 1178, http://dx.doi.org/10.1086/339678
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Gandhi RT; Walker BD, 2002, 'Immunologic control of HIV-1.', Annu Rev Med, vol. 53, pp. 149 - 172, http://dx.doi.org/10.1146/annurev.med.53.082901.104011
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Addo MM; Yu XG; Rosenberg ES; Walker BD; Altfeld M, 2002, 'Cytotoxic T-lymphocyte (CTL) responses directed against regulatory and accessory proteins in HIV-1 infection.', DNA Cell Biol, vol. 21, pp. 671 - 678, http://dx.doi.org/10.1089/104454902760330219
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Gandhi RT; Walker BD, 2002, 'Promises and pitfalls in the reconstitution of immunity in patients who have HIV-1 infection.', Curr Opin Immunol, vol. 14, pp. 487 - 494, http://dx.doi.org/10.1016/s0952-7915(02)00359-x
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Goulder PJR; Walker BD, 2002, 'HIV-1 superinfection--a word of caution.', N Engl J Med, vol. 347, pp. 756 - 758, http://dx.doi.org/10.1056/NEJMe020091
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Addo MM; Altfeld M; Rathod A; Yu M; Yu XG; Goulder PJR; Rosenberg ES; Walker BD, 2002, 'HIV-1 Vpu represents a minor target for cytotoxic T lymphocytes in HIV-1-infection.', AIDS, vol. 16, pp. 1071 - 1073, http://dx.doi.org/10.1097/00002030-200205030-00015
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Kuchar DL; Walker BD; Thorburn CW, 2002, 'Ventricular tachycardia following ingestion of a commonly used antihistamine', Medical Journal of Australia, vol. 176, pp. 429 - 430, http://dx.doi.org/10.5694/j.1326-5377.2002.tb04485.x
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Allen TM; Kelleher AD; Zaunders J; Walker BD, 2002, 'Supervised or structured treatment interruption (STI) and beyond...', Biofutur, pp. 52 - 58
    Journal articles | 2002
    Dr Bruce Duncan Walker
    Walker BD; Krahn AD; Skanes AC; Yee R, 2002, 'Syncope and polymorphic ventricular tachycardia', PACE - Pacing and Clinical Electrophysiology, vol. 25, pp. 1259 - 1261, http://dx.doi.org/10.1046/j.1460-9592.2002.01259.x
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Goulder PJ; Brander C; Tang Y; Tremblay C; Colbert RA; Addo MM; Rosenberg ES; Nguyen T; Allen R; Trocha A; Altfeld M; He S; Bunce M; Funkhouser R; Pelton SI; Burchett SK; McIntosh K; Korber BT; Walker BD, 2001, 'Evolution and transmission of stable CTL escape mutations in HIV infection.', Nature, vol. 412, pp. 334 - 338, http://dx.doi.org/10.1038/35085576
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Goulder PJ; Addo MM; Altfeld MA; Rosenberg ES; Tang Y; Govender U; Mngqundaniso N; Annamalai K; Vogel TU; Hammond M; Bunce M; Coovadia HM; Walker BD, 2001, 'Rapid definition of five novel HLA-A*3002-restricted human immunodeficiency virus-specific cytotoxic T-lymphocyte epitopes by elispot and intracellular cytokine staining assays.', J Virol, vol. 75, pp. 1339 - 1347, http://dx.doi.org/10.1128/JVI.75.3.1339-1347.2001
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Day CL; Shea AK; Altfeld MA; Olson DP; Buchbinder SP; Hecht FM; Rosenberg ES; Walker BD; Kalams SA, 2001, 'Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles.', J Virol, vol. 75, pp. 6279 - 6291, http://dx.doi.org/10.1128/JVI.75.14.6279-6291.2001
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Montefiori DC; Hill TS; Vo HT; Walker BD; Rosenberg ES, 2001, 'Neutralizing antibodies associated with viremia control in a subset of individuals after treatment of acute human immunodeficiency virus type 1 infection.', J Virol, vol. 75, pp. 10200 - 10207, http://dx.doi.org/10.1128/JVI.75.21.10200-10207.2001
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Altfeld MA; Livingston B; Reshamwala N; Nguyen PT; Addo MM; Shea A; Newman M; Fikes J; Sidney J; Wentworth P; Chesnut R; Eldridge RL; Rosenberg ES; Robbins GK; Brander C; Sax PE; Boswell S; Flynn T; Buchbinder S; Goulder PJ; Walker BD; Sette A; Kalams SA, 2001, 'Identification of novel HLA-A2-restricted human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte epitopes predicted by the HLA-A2 supertype peptide-binding motif.', J Virol, vol. 75, pp. 1301 - 1311, http://dx.doi.org/10.1128/JVI.75.3.1301-1311.2001
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Lauer GM; Walker BD, 2001, 'Hepatitis C virus infection.', N Engl J Med, vol. 345, pp. 41 - 52, http://dx.doi.org/10.1056/NEJM200107053450107
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Goulder PJ; Altfeld MA; Rosenberg ES; Nguyen T; Tang Y; Eldridge RL; Addo MM; He S; Mukherjee JS; Phillips MN; Bunce M; Kalams SA; Sekaly RP; Walker BD; Brander C, 2001, 'Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection.', J Exp Med, vol. 193, pp. 181 - 194, http://dx.doi.org/10.1084/jem.193.2.181
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Addo MM; Altfeld M; Rosenberg ES; Eldridge RL; Philips MN; Habeeb K; Khatri A; Brander C; Robbins GK; Mazzara GP; Goulder PJ; Walker BD; HIV Controller Study Collaboration , 2001, 'The HIV-1 regulatory proteins Tat and Rev are frequently targeted by cytotoxic T lymphocytes derived from HIV-1-infected individuals.', Proc Natl Acad Sci U S A, vol. 98, pp. 1781 - 1786, http://dx.doi.org/10.1073/pnas.98.4.1781
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Geiben-Lynn R; Kursar M; Brown NV; Kerr EL; Luster AD; Walker BD, 2001, 'Noncytolytic inhibition of X4 virus by bulk CD8(+) cells from human immunodeficiency virus type 1 (HIV-1)-infected persons and HIV-1-specific cytotoxic T lymphocytes is not mediated by beta-chemokines.', J Virol, vol. 75, pp. 8306 - 8316, http://dx.doi.org/10.1128/jvi.75.17.8306-8316.2001
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Norris PJ; Sumaroka M; Brander C; Moffett HF; Boswell SL; Nguyen T; Sykulev Y; Walker BD; Rosenberg ES, 2001, 'Multiple effector functions mediated by human immunodeficiency virus-specific CD4(+) T-cell clones.', J Virol, vol. 75, pp. 9771 - 9779, http://dx.doi.org/10.1128/JVI.75.20.9771-9779.2001
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Flores-Villanueva PO; Yunis EJ; Delgado JC; Vittinghoff E; Buchbinder S; Leung JY; Uglialoro AM; Clavijo OP; Rosenberg ES; Kalams SA; Braun JD; Boswell SL; Walker BD; Goldfeld AE, 2001, 'Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity.', Proc Natl Acad Sci U S A, vol. 98, pp. 5140 - 5145, http://dx.doi.org/10.1073/pnas.071548198
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Walker BD; Korber BT, 2001, 'Immune control of HIV: the obstacles of HLA and viral diversity.', Nat Immunol, vol. 2, pp. 473 - 475, http://dx.doi.org/10.1038/88656
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Altfeld M; Rosenberg ES; Shankarappa R; Mukherjee JS; Hecht FM; Eldridge RL; Addo MM; Poon SH; Phillips MN; Robbins GK; Sax PE; Boswell S; Kahn JO; Brander C; Goulder PJ; Levy JA; Mullins JI; Walker BD, 2001, 'Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection.', J Exp Med, vol. 193, pp. 169 - 180, http://dx.doi.org/10.1084/jem.193.2.169
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Wong DK; Dudley DD; Dohrenwend PB; Lauer GM; Chung RT; Thomas DL; Walker BD, 2001, 'Detection of diverse hepatitis C virus (HCV)-specific cytotoxic T lymphocytes in peripheral blood of infected persons by screening for responses to all translated proteins of HCV.', J Virol, vol. 75, pp. 1229 - 1235, http://dx.doi.org/10.1128/JVI.75.3.1229-1235.2001
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Altfeld M; Addo MM; Eldridge RL; Yu XG; Thomas S; Khatri A; Strick D; Phillips MN; Cohen GB; Islam SA; Kalams SA; Brander C; Goulder PJ; Rosenberg ES; Walker BD; HIV Study Collaboration , 2001, 'Vpr is preferentially targeted by CTL during HIV-1 infection.', J Immunol, vol. 167, pp. 2743 - 2752, http://dx.doi.org/10.4049/jimmunol.167.5.2743
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Altfeld M; Walker BD, 2001, 'Less is more? STI in acute and chronic HIV-1 infection.', Nat Med, vol. 7, pp. 881 - 884, http://dx.doi.org/10.1038/90901
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Vandenberg JI; Walker BD; Campbell TJ, 2001, 'HERG K+ channels: Friend and foe', Trends in Pharmacological Sciences, vol. 22, pp. 240 - 246, http://dx.doi.org/10.1016/S0165-6147(00)01662-X
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Kuritzkes DR; Walker BD, 2001, 'Targeting HIV', Cell, vol. 107, pp. 284 - 285, http://dx.doi.org/10.1016/s0092-8674(01)00561-x
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Cohen DE; Walker BD, 2001, 'Human immunodeficiency virus pathogenesis and prospects for immune control in patients with established infection.', Clin Infect Dis, vol. 32, pp. 1756 - 1768, http://dx.doi.org/10.1086/320759
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Walensky RP; Rosenberg ES; Ferraro MJ; Losina E; Walker BD; Freedberg KA, 2001, 'Investigation of primary human immunodeficiency virus infection in patients who test positive for heterophile antibody.', Clin Infect Dis, vol. 33, pp. 570 - 572, http://dx.doi.org/10.1086/321903
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Brander C; Matter-Reissmann UB; Jones NG; Walker BD; Sachs DH; Seebach JD, 2001, 'Inhibition of human NK cell-mediated cytotoxicity by exposure to ammonium chloride.', J Immunol Methods, vol. 252, pp. 1 - 14, http://dx.doi.org/10.1016/s0022-1759(01)00326-x
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Letvin NL; Walker BD, 2001, 'HIV versus the immune system: another apparent victory for the virus.', J Clin Invest, vol. 107, pp. 273 - 275, http://dx.doi.org/10.1172/JCI12174
    Journal articles | 2001
    Dr Bruce Duncan Walker
    Tie H; Walker BD; Singleton CB; Bursill JA; Wyse KR; Campbell TJ; Valenzuela SM; Breit SN, 2001, 'Clozapine and sudden death [10]', Journal of Clinical Psychopharmacology, vol. 21, pp. 630 - 632, http://dx.doi.org/10.1097/00004714-200112000-00023
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Altfeld MA; Trocha A; Eldridge RL; Rosenberg ES; Phillips MN; Addo MM; Sekaly RP; Kalams SA; Burchett SA; McIntosh K; Walker BD; Goulder PJ, 2000, 'Identification of dominant optimal HLA-B60- and HLA-B61-restricted cytotoxic T-lymphocyte (CTL) epitopes: rapid characterization of CTL responses by enzyme-linked immunospot assay.', J Virol, vol. 74, pp. 8541 - 8549, http://dx.doi.org/10.1128/jvi.74.18.8541-8549.2000
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Cao H; Mani I; Vincent R; Mugerwa R; Mugyenyi P; Kanki P; Ellner J; Walker BD, 2000, 'Cellular immunity to human immunodeficiency virus type 1 (HIV-1) clades: relevance to HIV-1 vaccine trials in Uganda.', J Infect Dis, vol. 182, pp. 1350 - 1356, http://dx.doi.org/10.1086/315868
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Rosenberg ES; Altfeld M; Poon SH; Phillips MN; Wilkes BM; Eldridge RL; Robbins GK; D'Aquila RT; Goulder PJ; Walker BD, 2000, 'Immune control of HIV-1 after early treatment of acute infection.', Nature, vol. 407, pp. 523 - 526, http://dx.doi.org/10.1038/35035103
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Goulder PJ; Tang Y; Brander C; Betts MR; Altfeld M; Annamalai K; Trocha A; He S; Rosenberg ES; Ogg G; O'Callaghan CA; Kalams SA; McKinney RE; Mayer K; Koup RA; Pelton SI; Burchett SK; McIntosh K; Walker BD, 2000, 'Functionally inert HIV-specific cytotoxic T lymphocytes do not play a major role in chronically infected adults and children.', J Exp Med, vol. 192, pp. 1819 - 1832, http://dx.doi.org/10.1084/jem.192.12.1819
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Goulder PJ; Brander C; Annamalai K; Mngqundaniso N; Govender U; Tang Y; He S; Hartman KE; O'Callaghan CA; Ogg GS; Altfeld MA; Rosenberg ES; Cao H; Kalams SA; Hammond M; Bunce M; Pelton SI; Burchett SA; McIntosh K; Coovadia HM; Walker BD, 2000, 'Differential narrow focusing of immunodominant human immunodeficiency virus gag-specific cytotoxic T-lymphocyte responses in infected African and caucasoid adults and children.', J Virol, vol. 74, pp. 5679 - 5690, http://dx.doi.org/10.1128/jvi.74.12.5679-5690.2000
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Severino ME; Sipsas NV; Nguyen PT; Kalams SA; Walker BD; Johnson RP; Yang OO, 2000, 'Inhibition of human immunodeficiency virus type 1 replication in primary CD4(+) T lymphocytes, monocytes, and dendritic cells by cytotoxic T lymphocytes.', J Virol, vol. 74, pp. 6695 - 6699, http://dx.doi.org/10.1128/jvi.74.14.6695-6699.2000
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Goulder PJ; Tang Y; Pelton SI; Walker BD, 2000, 'HLA-B57-restricted cytotoxic T-lymphocyte activity in a single infected subject toward two optimal epitopes, one of which is entirely contained within the other.', J Virol, vol. 74, pp. 5291 - 5299, http://dx.doi.org/10.1128/jvi.74.11.5291-5299.2000
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Martinez-Picado J; DePasquale MP; Kartsonis N; Hanna GJ; Wong J; Finzi D; Rosenberg E; Gunthard HF; Sutton L; Savara A; Petropoulos CJ; Hellmann N; Walker BD; Richman DD; Siliciano R; D'Aquila RT, 2000, 'Antiretroviral resistance during successful therapy of HIV type 1 infection.', Proc Natl Acad Sci U S A, vol. 97, pp. 10948 - 10953, http://dx.doi.org/10.1073/pnas.97.20.10948
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Goulder PJ; Lechner F; Klenerman P; McIntosh K; Walker BD, 2000, 'Characterization of a novel respiratory syncytial virus-specific human cytotoxic T-lymphocyte epitope.', J Virol, vol. 74, pp. 7694 - 7697, http://dx.doi.org/10.1128/jvi.74.16.7694-7697.2000
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Ostrowski MA; Justement SJ; Ehler L; Mizell SB; Lui S; Mican J; Walker BD; Thomas EK; Seder R; Fauci AS, 2000, 'The role of CD4+ T cell help and CD40 ligand in the in vitro expansion of HIV-1-specific memory cytotoxic CD8+ T cell responses.', J Immunol, vol. 165, pp. 6133 - 6141, http://dx.doi.org/10.4049/jimmunol.165.11.6133
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Tremblay CL; Giguel F; Merrill DP; Wong JT; Rosenberg E; Kalams S; Walker BD; D'Aquila RT; Hirsch MS, 2000, 'Marked differences in quantity of infectious human immunodeficiency virus type 1 detected in persons with controlled plasma viremia by a simple enhanced culture method.', J Clin Microbiol, vol. 38, pp. 4246 - 4248, http://dx.doi.org/10.1128/JCM.38.11.4246-4248.2000
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Tie H; Walker BD; Singleton CB; Valenzuela SM; Bursill JA; Wyse KR; Breit SN; Campbell TJ, 2000, 'Inhibiton of HERG potassium channels by the antimalarial agent halofantrine', British Journal of Pharmacology, vol. 130, pp. 1967 - 1975, http://dx.doi.org/10.1038/sj.bjp.0703470
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Walker BD; Goulder PJ, 2000, 'AIDS. Escape from the immune system.', Nature, vol. 407, pp. 313 - 314, http://dx.doi.org/10.1038/35030283
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Tie H; Walker BD; Valenzuela SM; Breit SN; Campbell TJ, 2000, 'The heart of psychotropic drug therapy.', Lancet, vol. 355, pp. 1825, http://dx.doi.org/10.1016/S0140-6736(05)73083-X
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Brander C; Walker BD, 2000, 'Modulation of host immune responses by clinically relevant human DNA and RNA viruses.', Curr Opin Microbiol, vol. 3, pp. 379 - 386, http://dx.doi.org/10.1016/s1369-5274(00)00108-9
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Schooley RT; Spino C; Kuritzkes D; Walker BD; Valentine FA; Hirsch MS; Cooney E; Friedland G; Kundu S; Merigan TC; McElrath MJ; Collier A; Plaeger S; Mitsuyasu R; Kahn J; Haslett P; Uherova P; deGruttola V; Chiu S; Zhang B; Jones G; Bell D; Ketter N; Twadell T; Chernoff D; Rosandich M, 2000, 'Two double-blinded, randomized, comparative trials of 4 human immunodeficiency virus type 1 (HIV-1) envelope vaccines in HIV-1-infected individuals across a spectrum of disease severity: AIDS Clinical Trials Groups 209 and 214.', J Infect Dis, vol. 182, pp. 1357 - 1364, http://dx.doi.org/10.1086/315860
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Le Gall S; Buseyne F; Trocha A; Walker BD; Heard JM; Schwartz O, 2000, 'Distinct trafficking pathways mediate Nef-induced and clathrin-dependent major histocompatibility complex class I down-regulation.', J Virol, vol. 74, pp. 9256 - 9266, http://dx.doi.org/10.1128/jvi.74.19.9256-9266.2000
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Walker BD; Singleton CB; Tie H; Bursill JA; Wyse KR; Valenzuela SM; Breit SN; Campbell LV, 2000, 'Comparative effects of azimilide and ambasilide on the human ether-a-go-go-related gene (HERG) potassium channel', Cardiovascular Research, vol. 48, pp. 44 - 58, http://dx.doi.org/10.1016/S0008-6363(00)00155-3
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Goulder PJR; Tang Y; Pelton SI; Walker BD, 2000, 'HLA-B57-Restricted Cytotoxic T-Lymphocyte Activity in a Single Infected Subject toward Two Optimal Epitopes, One of Which Is Entirely Contained within the Other', Journal of Virology, vol. 74, pp. 5291 - 5299, http://dx.doi.org/10.1128/.74.11.5291-5299.2000
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Cao H; Walker BD, 2000, 'Immunopathogenesis of HIV-1 infection.', Clin Dermatol, vol. 18, pp. 401 - 410, http://dx.doi.org/10.1016/s0738-081x(99)00135-2
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Walker BD; Rosenberg ES, 2000, 'Containing HIV after infection.', Nat Med, vol. 6, pp. 1094 - 1095, http://dx.doi.org/10.1038/80415
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Singleton CB; Walker BD; Campbell TJ, 2000, 'N-3 polyunsaturated fatty acids and cardiac mortality', Australian and New Zealand Journal of Medicine, vol. 30, pp. 246 - 251, http://dx.doi.org/10.1111/j.1445-5994.2000.tb00815.x
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Lange JF; Kuchar DL; Thorburn CW; Vogels PH; Walker BD, 2000, 'Quality of life pre- and post-transcatheter ablation for supraventricular tachycardia', Heart, Lung and Circulation, vol. 9, pp. A86 - A86, http://dx.doi.org/10.1046/j.1443-9506.2000.05870.x
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Singleton CB; Walker BD; Tie H; Bursill JA; Wyse KR; Valenzuela SM; Breit SN; Campbell TJ, 2000, 'Potent blockade by quinidine of the Kv4.3 current: Significance with regard to treatment of the brugada syndrome', Heart, Lung and Circulation, vol. 9, pp. A92 - A92, http://dx.doi.org/10.1046/j.1443-9506.2000.06115.x
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Tie H; Walker BD; Singleton CB; Bursill J; Wyse K; Valenzuela S; Breit SN; Campbell TJ, 2000, 'The antipsychotic agents thioridazine, chlorpromazine and clozapine block the human-ether-a-go-go-related gene (HERG) potassium channel: Cellular mechanism for proarrhythmia', Heart, Lung and Circulation, vol. 9, pp. A109 - A109, http://dx.doi.org/10.1046/j.1443-9506.2000.06796.x
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Walker BD; Tie H; Singleton CB; Bursill JA; Wyse KR; Valenzuela SM; Breit SN; Campbell TJ, 2000, 'Hyperkalaemia and acidosis modify HERG channel biophysical properties and antagonise inhibition by sotalol', Heart, Lung and Circulation, vol. 9, pp. A131 - A131, http://dx.doi.org/10.1046/j.1443-9506.2000.07650.x
    Journal articles | 2000
    Dr Bruce Duncan Walker
    Kuchar D; Lange J; Vogels P; Walker B; Thorburn C, 2000, 'Reduced benefit of the implantable defibrillator in patients undergoing coronary revascularization', Heart, Lung and Circulation, vol. 9, pp. A148 - A148, http://dx.doi.org/10.1046/j.1443-9506.2000.08321.x
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Walker BD; Valenzuela SM; Singleton CB; Tie H; Bursill JA; Wyse KR; Qui MR; Breit SN; Campbell TJ, 1999, 'Inhibition of HERG channels stably expressed in a mammalian cell line by the antianginal agent perhexiline maleate.', British Journal of Pharmacology, vol. 127, pp. 243 - 251, http://dx.doi.org/10.1038/sj.bjp.0702502
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Finzi D; Blankson J; Siliciano JD; Margolick JB; Chadwick K; Pierson T; Smith K; Lisziewicz J; Lori F; Flexner C; Quinn TC; Chaisson RE; Rosenberg E; Walker B; Gange S; Gallant J; Siliciano RF, 1999, 'Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy.', Nat Med, vol. 5, pp. 512 - 517, http://dx.doi.org/10.1038/8394
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Wilson CC; Brown RC; Korber BT; Wilkes BM; Ruhl DJ; Sakamoto D; Kunstman K; Luzuriaga K; Hanson IC; Widmayer SM; Wiznia A; Clapp S; Ammann AJ; Koup RA; Wolinsky SM; Walker BD, 1999, 'Frequent detection of escape from cytotoxic T-lymphocyte recognition in perinatal human immunodeficiency virus (HIV) type 1 transmission: the ariel project for the prevention of transmission of HIV from mother to infant.', J Virol, vol. 73, pp. 3975 - 3985, http://dx.doi.org/10.1128/JVI.73.5.3975-3985.1999
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Yang OO; Swanberg SL; Lu Z; Dziejman M; McCoy J; Luster AD; Walker BD; Herrmann SH, 1999, 'Enhanced inhibition of human immunodeficiency virus type 1 by Met-stromal-derived factor 1beta correlates with down-modulation of CXCR4.', J Virol, vol. 73, pp. 4582 - 4589, http://dx.doi.org/10.1128/JVI.73.6.4582-4589.1999
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Hay CM; Ruhl DJ; Basgoz NO; Wilson CC; Billingsley JM; DePasquale MP; D'Aquila RT; Wolinsky SM; Crawford JM; Montefiori DC; Walker BD, 1999, 'Lack of viral escape and defective in vivo activation of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes in rapidly progressive infection.', J Virol, vol. 73, pp. 5509 - 5519, http://dx.doi.org/10.1128/JVI.73.7.5509-5519.1999
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Kalams SA; Buchbinder SP; Rosenberg ES; Billingsley JM; Colbert DS; Jones NG; Shea AK; Trocha AK; Walker BD, 1999, 'Association between virus-specific cytotoxic T-lymphocyte and helper responses in human immunodeficiency virus type 1 infection.', J Virol, vol. 73, pp. 6715 - 6720, http://dx.doi.org/10.1128/JVI.73.8.6715-6720.1999
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Kalams SA; Goulder PJ; Shea AK; Jones NG; Trocha AK; Ogg GS; Walker BD, 1999, 'Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy.', J Virol, vol. 73, pp. 6721 - 6728, http://dx.doi.org/10.1128/JVI.73.8.6721-6728.1999
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Brander C; Yang OO; Jones NG; Lee Y; Goulder P; Johnson RP; Trocha A; Colbert D; Hay C; Buchbinder S; Bergmann CC; Zweerink HJ; Wolinsky S; Blattner WA; Kalams SA; Walker BD, 1999, 'Efficient processing of the immunodominant, HLA-A*0201-restricted human immunodeficiency virus type 1 cytotoxic T-lymphocyte epitope despite multiple variations in the epitope flanking sequences.', J Virol, vol. 73, pp. 10191 - 10198, http://dx.doi.org/10.1128/JVI.73.12.10191-10198.1999
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Walker BD; Singleton CB; Bursill JA; Wyse KR; Valenzuela SM; Qui MR; Breit SN; Campbell TJ, 1999, 'Inhibition of the human ether-a-go-go-related gene (HERG) potassium channel by cisapride: affinity for open and inactivated states', British Journal of Pharmacology, vol. 128, pp. 444 - 450, http://dx.doi.org/10.1038/sj.bjp.0702774
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Brander C; Walker BD, 1999, 'T lymphocyte responses in HIV-1 infection: implications for vaccine development.', Curr Opin Immunol, vol. 11, pp. 451 - 459, http://dx.doi.org/10.1016/S0952-7915(99)80076-4
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Goulder PJ; Walker BD, 1999, 'The great escape - AIDS viruses and immune control.', Nat Med, vol. 5, pp. 1233 - 1235, http://dx.doi.org/10.1038/15184
    Journal articles | 1999
    Dr Bruce Duncan Walker
    &NA; , 1999, 'Erratum', JAIDS Journal of Acquired Immune Deficiency Syndromes, vol. 22, pp. 207 - 207, http://dx.doi.org/10.1097/00126334-199910010-00015
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Rodrigo AG; Shpaer EG; Delwart EL; Iversen AK; Gallo MV; Brojatsch J; Hirsch MS; Walker BD; Mullins JI, 1999, 'Coalescent estimates of HIV-1 generation time in vivo.', Proc Natl Acad Sci U S A, vol. 96, pp. 2187 - 2191, http://dx.doi.org/10.1073/pnas.96.5.2187
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Brander C; Jones N; Kedes D; Ganem D; Martin J; Osmond D; Southwood S; Walker BD; Scadden D, 1999, 'IDENTIFICATION OF A HLA-A *0201 RESTRICTED, OPTIMAL CTL EPITOPE IN THE KSHV KAPOSIN PROTEIN', JAIDS: Journal of Acquired Immune Deficiency Syndromes, vol. 21, pp. A11 - A11, http://dx.doi.org/10.1097/00126334-199905010-00026
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Mani I; Cao H; Hom D; Johnson JL; Mugerwa RD; Travers KU; Caliendo AM; Walker BD; Kanki PJ, 1999, 'Plasma RNA viral load as measured by the branched DNA and nucleic acid sequence-based amplification assays of HIV-1 subtypes A and D in Uganda.', J Acquir Immune Defic Syndr, vol. 22, pp. 208 - 209, http://dx.doi.org/10.1097/00126334-199910010-00016
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Lisziewicz J; Rosenberg E; Lieberman J; Jessen H; Lopalco L; Siliciano R; Walker B; Lori F, 1999, 'Control of HIV despite the discontinuation of antiretroviral therapy.', N Engl J Med, vol. 340, pp. 1683 - 1684, http://dx.doi.org/10.1056/NEJM199905273402114
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Wagner R; Leschonsky B; Harrer E; Paulus C; Weber C; Walker BD; Buchbinder S; Wolf H; Kalden JR; Harrer T, 1999, 'Molecular and functional analysis of a conserved CTL epitope in HIV-1 p24 recognized from a long-term nonprogressor: constraints on immune escape associated with targeting a sequence essential for viral replication.', J Immunol, vol. 162, pp. 3727 - 3734, https://www.ncbi.nlm.nih.gov/pubmed/10092836
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Mani I; Cao H; Hom D; Johnson JL; Mugerwa RD; Travers KU; Caliendo AM; Walker BD; Kanki PJ, 1999, 'Plasma RNA Viral Load as Measured by the Branched DNA and Nucleic Acid Sequence–Based Amplification Assays of HIV-1 Subtypes A and D in Uganda', JAIDS Journal of Acquired Immune Deficiency Syndromes, vol. 22, pp. 208 - 208, http://dx.doi.org/10.1097/00126334-199910010-00016
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Brander C; Goulder PJ; Luzuriaga K; Yang OO; Hartman KE; Jones NG; Walker BD; Kalams SA, 1999, 'Persistent HIV-1-specific CTL clonal expansion despite high viral burden post in utero HIV-1 infection.', J Immunol, vol. 162, pp. 4796 - 4800, https://www.ncbi.nlm.nih.gov/pubmed/10202022
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Goulder PJ; Rowland-Jones SL; McMichael AJ; Walker BD, 1999, 'Anti-HIV cellular immunity: recent advances towards vaccine design.', AIDS, vol. 13 Suppl A, pp. S121 - S136, https://www.ncbi.nlm.nih.gov/pubmed/10885771
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Singleton CB; Valenzuela SM; Walker BD; Tie H; Wyse KR; Bursill JA; Qui MR; Breit SN; Campbell TJ, 1999, 'Blockade by N-3 polyunsaturated fatty acid of the Kv4.3 current stably expressed in Chinese Hamster ovary cells', British Journal of Pharmacology, vol. 127, pp. 941 - 948, http://dx.doi.org/10.1038/sj.bjp.0702638
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Little SJ; Daar ES; D'Aquila RT; Keiser PH; Connick E; Whitcomb JM; Hellmann NS; Petropoulos CJ; Sutton L; Pitt JA; Rosenberg ES; Koup RA; Walker BD; Richman DD, 1999, 'Reduced antiretroviral drug susceptibility among patients with primary HIV infection.', JAMA, vol. 282, pp. 1142 - 1149, http://dx.doi.org/10.1001/jama.282.12.1142
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Rosenberg ES; LaRosa L; Flynn T; Robbins G; Walker BD, 1999, 'Characterization of HIV-1-specific T-helper cells in acute and chronic infection.', Immunol Lett, vol. 66, pp. 89 - 93, http://dx.doi.org/10.1016/s0165-2478(98)00165-5
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Merrill DP; Martinez-Picado J; Tremblay C; Sax PE; Boswell SL; Wong JT; D'Aquila RT; Walker BD; Hirsch MS, 1999, 'Improved CD4 lymphocyte outgrowth in response to effective antiretroviral therapy.', J Infect Dis, vol. 179, pp. 345 - 351, http://dx.doi.org/10.1086/314591
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Lori F; Jessen H; Lieberman J; Finzi D; Rosenberg E; Tinelli C; Walker B; Siliciano RF; Lisziewicz J, 1999, 'Treatment of human immunodeficiency virus infection with hydroxyurea, didanosine, and a protease inhibitor before seroconversion is associated with normalized immune parameters and limited viral reservoir.', J Infect Dis, vol. 180, pp. 1827 - 1832, http://dx.doi.org/10.1086/315113
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Lori F; Rosenberg E; Lieberman J; Foli A; Maserati R; Seminari E; Alberici F; Walker B; Lisziewicz J, 1999, 'Hydroxyurea and didanosine long-term treatment prevents HIV breakthrough and normalizes immune parameters.', AIDS Res Hum Retroviruses, vol. 15, pp. 1333 - 1338, http://dx.doi.org/10.1089/088922299310034
    Journal articles | 1999
    Dr Bruce Duncan Walker
    Walker BD; Thorburn CW; Kuchar DL, 1999, 'Recurrent atrial electrode displacement complicating a single lead VDD pacing system', PACE - Pacing and Clinical Electrophysiology, vol. 22, pp. 1688 - 1691, http://dx.doi.org/10.1111/j.1540-8159.1999.tb00391.x
    Journal articles | 1998
    Dr Bruce Duncan Walker
    Kalams SA; Walker BD, 1998, 'The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses.', J Exp Med, vol. 188, pp. 2199 - 2204, http://dx.doi.org/10.1084/jem.188.12.2199
    Journal articles | 1998
    Dr Bruce Duncan Walker
    Kahn JO; Walker BD, 1998, 'Acute human immunodeficiency virus type 1 infection.', N Engl J Med, vol. 339, pp. 33 - 39, http://dx.doi.org/10.1056/NEJM199807023390107
    Journal articles | 1998
    Dr Bruce Duncan Walker
    Collins KL; Chen BK; Kalams SA; Walker BD; Baltimore D, 1998, 'HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.', Nature, vol. 391, pp. 397 - 401, http://dx.doi.org/10.1038/34929
    Journal articles | 1998
    Dr Bruce Duncan Walker
    Brander C; Hartman KE; Trocha AK; Jones NG; Johnson RP; Korber B; Wentworth P; Buchbinder SP; Wolinsky S; Walker BD; Kalams SA, 1998, 'Lack of strong immune selection pressure by the immunodominant, HLA-A*0201-restricted cytotoxic T lymphocyte response in chronic human immunodeficiency virus-1 infection.', J Clin Invest, vol. 101, pp. 2559 - 2566, http://dx.doi.org/10.1172/JCI2405
    Journal articles | 1998
    Dr Bruce Duncan Walker
    Wagner L; Yang OO; Garcia-Zepeda EA; Ge Y; Kalams SA; Walker BD; Pasternack MS; Luster AD, 1998, 'Beta-chemokines are released from HIV-1-specific cytolytic T-cell granules complexed to proteoglycans.', Nature, vol. 391, pp. 908 - 911, http://dx.doi.org/10.1038/36129
    Journal articles | 1998
    Dr Bruce Duncan Walker
    Delwart EL; Mullins JI; Gupta P; Learn GH; Holodniy M; Katzenstein D; Walker BD; Singh MK, 1998, 'Human immunodeficiency virus type 1 populations in blood and semen.', J Virol, vol. 72, pp. 617 - 623, http://dx.doi.org/10.1128/JVI.72.1.617-623.1998
    Journal articles | 1998
    Dr Bruce Duncan Walker
    Jin X; Roberts CG; Nixon DF; Cao Y; Ho DD; Walker BD; Muldoon M; Korber BT; Koup RA, 1998, 'Longitudinal and cross-sectional analysis of cytotoxic T lymphocyte responses and their relationship to vertical human immunodeficiency virus transmission. ARIEL Project Investigators.', J Infect Dis, vol. 178, pp. 1317 - 1326, http://dx.doi.org/10.1086/314455
    Journal articles | 1998
    Dr Bruce Duncan Walker
    Walker BD; Basgoz N, 1998, 'Treat HIV-1 infection like other infections--treat it.', JAMA, vol. 280, pp. 91 - 93, http://dx.doi.org/10.1001/jama.280.1.91
    Journal articles | 1998
    Dr Bruce Duncan Walker
    Brander C; Walker BD; Korber B, 1998, 'Comment to the Letter to the Editor', AIDS Research and Human Retroviruses, vol. 14, pp. 923 - 924, http://dx.doi.org/10.1089/aid.1998.14.923
    Journal articles | 1998
    Dr Bruce Duncan Walker
    Wong DK; Dudley DD; Afdhal NH; Dienstag J; Rice CM; Wang L; Houghton M; Walker BD; Koziel MJ, 1998, 'Liver-derived CTL in hepatitis C virus infection: breadth and specificity of responses in a cohort of persons with chronic infection.', J Immunol, vol. 160, pp. 1479 - 1488, https://www.ncbi.nlm.nih.gov/pubmed/9570570
    Journal articles | 1998
    Dr Bruce Duncan Walker
    Rosenberg ES; Walker BD, 1998, 'HIV type 1-specific helper T cells: a critical host defense.', AIDS Res Hum Retroviruses, vol. 14 Suppl 2, pp. S143 - S147, https://www.ncbi.nlm.nih.gov/pubmed/9672231
    Journal articles | 1998
    Dr Bruce Duncan Walker
    Connor RI; Korber BT; Graham BS; Hahn BH; Ho DD; Walker BD; Neumann AU; Vermund SH; Mestecky J; Jackson S; Fenamore E; Cao Y; Gao F; Kalams S; Kunstman KJ; McDonald D; McWilliams N; Trkola A; Moore JP; Wolinsky SM, 1998, 'Immunological and virological analyses of persons infected by human immunodeficiency virus type 1 while participating in trials of recombinant gp120 subunit vaccines.', J Virol, vol. 72, pp. 1552 - 1576, http://dx.doi.org/10.1128/JVI.72.2.1552-1576.1998
    Journal articles | 1998
    Dr Bruce Duncan Walker
    Walter JB; Garboczi DN; Fan QR; Zhou X; Walker BD; Eisen HN, 1998, 'A mutant human beta2-microglobulin can be used to generate diverse multimeric class I peptide complexes as specific probes for T cell receptors.', J Immunol Methods, vol. 214, pp. 41 - 50, http://dx.doi.org/10.1016/s0022-1759(98)00035-0
    Journal articles | 1998
    Dr Bruce Duncan Walker
    Harrer T; Harrer E; Barbosa P; Kaufmann F; Wagner R; Brüggemann S; Kalden JR; Feinberg M; Johnson RP; Buchbinder S; Walker BD, 1998, 'Recognition of two overlapping CTL epitopes in HIV-1 p17 by CTL from a long-term nonprogressing HIV-1-infected individual.', J Immunol, vol. 161, pp. 4875 - 4881, https://www.ncbi.nlm.nih.gov/pubmed/9794421
    Journal articles | 1997
    Dr Bruce Duncan Walker
    Koziel MJ; Walker BD, 1997, 'Characteristics of the intrahepatic cytotoxic T lymphocyte response in chronic hepatitis C virus infection.', Springer Semin Immunopathol, vol. 19, pp. 69 - 83, http://dx.doi.org/10.1007/BF00945026
    Journal articles | 1997
    Dr Bruce Duncan Walker
    Rosenberg ES; Billingsley JM; Caliendo AM; Boswell SL; Sax PE; Kalams SA; Walker BD, 1997, 'Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia.', Science, vol. 278, pp. 1447 - 1450, http://dx.doi.org/10.1126/science.278.5342.1447
    Journal articles | 1997
    Dr Bruce Duncan Walker
    Cao H; Kanki P; Sankalé JL; Dieng-Sarr A; Mazzara GP; Kalams SA; Korber B; Mboup S; Walker BD, 1997, 'Cytotoxic T-lymphocyte cross-reactivity among different human immunodeficiency virus type 1 clades: implications for vaccine development.', J Virol, vol. 71, pp. 8615 - 8623, http://dx.doi.org/10.1128/JVI.71.11.8615-8623.1997
    Journal articles | 1997
    Dr Bruce Duncan Walker
    Wilson CC; Kalams SA; Wilkes BM; Ruhl DJ; Gao F; Hahn BH; Hanson IC; Luzuriaga K; Wolinsky S; Koup R; Buchbinder SP; Johnson RP; Walker BD, 1997, 'Overlapping epitopes in human immunodeficiency virus type 1 gp120 presented by HLA A, B, and C molecules: effects of viral variation on cytotoxic T-lymphocyte recognition.', J Virol, vol. 71, pp. 1256 - 1264, http://dx.doi.org/10.1128/JVI.71.2.1256-1264.1997
    Journal articles | 1997
    Dr Bruce Duncan Walker
    Yang OO; Kalams SA; Trocha A; Cao H; Luster A; Johnson RP; Walker BD, 1997, 'Suppression of human immunodeficiency virus type 1 replication by CD8+ cells: evidence for HLA class I-restricted triggering of cytolytic and noncytolytic mechanisms.', J Virol, vol. 71, pp. 3120 - 3128, http://dx.doi.org/10.1128/JVI.71.4.3120-3128.1997
    Journal articles | 1997
    Dr Bruce Duncan Walker
    Yang OO; Tran AC; Kalams SA; Johnson RP; Roberts MR; Walker BD, 1997, 'Lysis of HIV-1-infected cells and inhibition of viral replication by universal receptor T cells.', Proc Natl Acad Sci U S A, vol. 94, pp. 11478 - 11483, http://dx.doi.org/10.1073/pnas.94.21.11478
    Journal articles | 1997
    Dr Bruce Duncan Walker
    Koziel MJ; Wong DK; Dudley D; Houghton M; Walker BD, 1997, 'Hepatitis C virus-specific cytolytic T lymphocyte and T helper cell responses in seronegative persons.', J Infect Dis, vol. 176, pp. 859 - 866, http://dx.doi.org/10.1086/516546
    Journal articles | 1997
    Dr Bruce Duncan Walker
    Sipsas NV; Kalams SA; Trocha A; He S; Blattner WA; Walker BD; Johnson RP, 1997, 'Identification of type-specific cytotoxic T lymphocyte responses to homologous viral proteins in laboratory workers accidentally infected with HIV-1.', J Clin Invest, vol. 99, pp. 752 - 762, http://dx.doi.org/10.1172/JCI119221
    Journal articles | 1997
    Dr Bruce Duncan Walker
    Walter JB; Brander C; Mammen M; Garboczi DN; Kalams SA; Whitesides GM; Walker BD; Eisen HN, 1997, 'Stimulation of human cytotoxic T cells with HIV-1-derived peptides presented by recombinant HLA-A2 peptide complexes.', Int Immunol, vol. 9, pp. 451 - 459, http://dx.doi.org/10.1093/intimm/9.3.451
    Journal articles | 1997
    Dr Bruce Duncan Walker
    Jassoy C; Walker BD, 1997, 'HIV-1-specific cytotoxic T lymphocytes and the control of HIV-1 replication.', Springer Semin Immunopathol, vol. 18, pp. 341 - 354, http://dx.doi.org/10.1007/BF00813502
    Journal articles | 1997
    Dr Bruce Duncan Walker
    Threlkeld SC; Wentworth PA; Kalams SA; Wilkes BM; Ruhl DJ; Keogh E; Sidney J; Southwood S; Walker BD; Sette A, 1997, 'Degenerate and promiscuous recognition by CTL of peptides presented by the MHC class I A3-like superfamily: implications for vaccine development.', J Immunol, vol. 159, pp. 1648 - 1657, https://www.ncbi.nlm.nih.gov/pubmed/9257824
    Journal articles | 1996
    Dr Bruce Duncan Walker
    Yang OO; Kalams SA; Rosenzweig M; Trocha A; Jones N; Koziel M; Walker BD; Johnson RP, 1996, 'Efficient lysis of human immunodeficiency virus type 1-infected cells by cytotoxic T lymphocytes.', J Virol, vol. 70, pp. 5799 - 5806, http://dx.doi.org/10.1128/JVI.70.9.5799-5806.1996
    Journal articles | 1996
    Dr Bruce Duncan Walker
    Kalams SA; Johnson RP; Dynan MJ; Hartman KE; Harrer T; Harrer E; Trocha AK; Blattner WA; Buchbinder SP; Walker BD, 1996, 'T cell receptor usage and fine specificity of human immunodeficiency virus 1-specific cytotoxic T lymphocyte clones: analysis of quasispecies recognition reveals a dominant response directed against a minor in vivo variant.', J Exp Med, vol. 183, pp. 1669 - 1679, http://dx.doi.org/10.1084/jem.183.4.1669
    Journal articles | 1996
    Dr Bruce Duncan Walker
    Harrer T; Harrer E; Kalams SA; Barbosa P; Trocha A; Johnson RP; Elbeik T; Feinberg MB; Buchbinder SP; Walker BD, 1996, 'Cytotoxic T lymphocytes in asymptomatic long-term nonprogressing HIV-1 infection. Breadth and specificity of the response and relation to in vivo viral quasispecies in a person with prolonged infection and low viral load.', J Immunol, vol. 156, pp. 2616 - 2623, https://www.ncbi.nlm.nih.gov/pubmed/8786327
    Journal articles | 1996
    Dr Bruce Duncan Walker
    Harrer E; Harrer T; Barbosa P; Feinberg M; Johnson RP; Buchbinder S; Walker BD, 1996, 'Recognition of the highly conserved YMDD region in the human immunodeficiency virus type 1 reverse transcriptase by HLA-A2-restricted cytotoxic T lymphocytes from an asymptomatic long-term nonprogressor.', J Infect Dis, vol. 173, pp. 476 - 479, http://dx.doi.org/10.1093/infdis/173.2.476
    Journal articles | 1996
    Dr Bruce Duncan Walker
    Harrer T; Harrer E; Kalams SA; Elbeik T; Staprans SI; Feinberg MB; Cao Y; Ho DD; Yilma T; Caliendo AM; Johnson RP; Buchbinder SP; Walker BD, 1996, 'Strong cytotoxic T cell and weak neutralizing antibody responses in a subset of persons with stable nonprogressing HIV type 1 infection.', AIDS Res Hum Retroviruses, vol. 12, pp. 585 - 592, http://dx.doi.org/10.1089/aid.1996.12.585
    Journal articles | 1995
    Dr Bruce Duncan Walker
    Heinkelein M; Schneider-Schaulies J; Walker BD; Jassoy C, 1995, 'Inhibition of cytotoxicity and cytokine release of CD8+ HIV-specific cytotoxic T lymphocytes by pentoxifylline.', J Acquir Immune Defic Syndr Hum Retrovirol, vol. 10, pp. 417 - 424, http://dx.doi.org/10.1097/00042560-199512000-00004
    Journal articles | 1995
    Dr Bruce Duncan Walker
    Iversen AK; Shpaer EG; Rodrigo AG; Hirsch MS; Walker BD; Sheppard HW; Merigan TC; Mullins JI, 1995, 'Persistence of attenuated rev genes in a human immunodeficiency virus type 1-infected asymptomatic individual.', J Virol, vol. 69, pp. 5743 - 5753, http://dx.doi.org/10.1128/JVI.69.9.5743-5753.1995
    Journal articles | 1995
    Dr Bruce Duncan Walker
    Koziel MJ; Dudley D; Afdhal N; Grakoui A; Rice CM; Choo QL; Houghton M; Walker BD, 1995, 'HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release.', J Clin Invest, vol. 96, pp. 2311 - 2321, http://dx.doi.org/10.1172/JCI118287
    Journal articles | 1995
    Dr Bruce Duncan Walker
    Hammond SA; Johnson RP; Kalams SA; Walker BD; Takiguchi M; Safrit JT; Koup RA; Siliciano RF, 1995, 'An epitope-selective, transporter associated with antigen presentation (TAP)-1/2-independent pathway and a more general TAP-1/2-dependent antigen-processing pathway allow recognition of the HIV-1 envelope glycoprotein by CD8+ CTL.', J Immunol, vol. 154, pp. 6140 - 6156, https://www.ncbi.nlm.nih.gov/pubmed/7538543
    Journal articles | 1995
    Dr Bruce Duncan Walker
    Price P; Johnson RP; Scadden DT; Jassoy C; Rosenthal T; Kalams S; Walker BD, 1995, 'Cytotoxic CD8+ T lymphocytes reactive with human immunodeficiency virus-1 produce granulocyte/macrophage colony-stimulating factor and variable amounts of interleukins 2, 3, and 4 following stimulation with the cognate epitope.', Clin Immunol Immunopathol, vol. 74, pp. 100 - 106, http://dx.doi.org/10.1006/clin.1995.1014
    Journal articles | 1995
    Dr Bruce Duncan Walker
    Jassoy C; Walker BD, 1995, 'T lymphocytes and their cytokines in human immunodeficiency virus (HIV) infection: implications for associated neoplasias.', Crit Rev Oncog, vol. 6, pp. 275 - 289, http://dx.doi.org/10.1615/critrevoncog.v6.i3-6.50
    Journal articles | 1995
    Dr Bruce Duncan Walker
    Wilson CC; Wong JT; Girard DD; Merrill DP; Dynan M; An DD; Kalams SA; Johnson RP; Hirsch MS; D'Aquila RT, 1995, 'Ex vivo expansion of CD4 lymphocytes from human immunodeficiency virus type 1-infected persons in the presence of combination antiretroviral agents.', J Infect Dis, vol. 172, pp. 88 - 96, http://dx.doi.org/10.1093/infdis/172.1.88
    Journal articles | 1994
    Dr Bruce Duncan Walker
    Johnson RP; Hammond SA; Trocha A; Siliciano RF; Walker BD, 1994, 'Induction of a major histocompatibility complex class I-restricted cytotoxic T-lymphocyte response to a highly conserved region of human immunodeficiency virus type 1 (HIV-1) gp120 in seronegative humans immunized with a candidate HIV-1 vaccine.', J Virol, vol. 68, pp. 3145 - 3153, http://dx.doi.org/10.1128/JVI.68.5.3145-3153.1994
    Journal articles | 1994
    Dr Bruce Duncan Walker
    Delwart EL; Sheppard HW; Walker BD; Goudsmit J; Mullins JI, 1994, 'Human immunodeficiency virus type 1 evolution in vivo tracked by DNA heteroduplex mobility assays.', J Virol, vol. 68, pp. 6672 - 6683, http://dx.doi.org/10.1128/JVI.68.10.6672-6683.1994
    Journal articles | 1994
    Dr Bruce Duncan Walker
    Tsomides TJ; Aldovini A; Johnson RP; Walker BD; Young RA; Eisen HN, 1994, 'Naturally processed viral peptides recognized by cytotoxic T lymphocytes on cells chronically infected by human immunodeficiency virus type 1.', J Exp Med, vol. 180, pp. 1283 - 1293, http://dx.doi.org/10.1084/jem.180.4.1283
    Journal articles | 1994
    Dr Bruce Duncan Walker
    Mestecky J; Walker MC; Mathieson BJ; Walker BD, 1994, 'Conference on advances in AIDS vaccine development--1993. Summary: Mucosal Immunity Workshop.', AIDS Res Hum Retroviruses, vol. 10 Suppl 2, pp. S165 - S170, https://www.ncbi.nlm.nih.gov/pubmed/7865293
    Journal articles | 1994
    Dr Bruce Duncan Walker
    Walker MC; Walker BD; Mestecky J; Mathieson BJ, 1994, 'Conference on advances in AIDS vaccine development--1993. Summary: cytotoxic T-cell Immunity Workshop.', AIDS Res Hum Retroviruses, vol. 10 Suppl 2, pp. S177 - S179, https://www.ncbi.nlm.nih.gov/pubmed/7865295
    Journal articles | 1994
    Dr Bruce Duncan Walker
    Johnson RP; Hammond SA; Trocha A; Siliciano RF; Walker BD, 1994, 'Epitope specificity of MHC restricted cytotoxic T lymphocytes induced by candidate HIV-1 vaccine.', AIDS Res Hum Retroviruses, vol. 10 Suppl 2, pp. S73 - S75, https://www.ncbi.nlm.nih.gov/pubmed/7532425
    Journal articles | 1994
    Dr Bruce Duncan Walker
    Harrer E; Harrer T; Buchbinder S; Mann DL; Feinberg M; Yilma T; Johnson RP; Walker BD, 1994, 'HIV-1-specific cytotoxic T lymphocyte response in healthy, long-term nonprogressing seropositive persons.', AIDS Res Hum Retroviruses, vol. 10 Suppl 2, pp. S77 - S78, https://www.ncbi.nlm.nih.gov/pubmed/7532426
    Journal articles | 1994
    Dr Bruce Duncan Walker
    Kalams SA; Johnson RP; Trocha AK; Dynan MJ; Ngo HS; D'Aquila RT; Kurnick JT; Walker BD, 1994, 'Longitudinal analysis of T cell receptor (TCR) gene usage by human immunodeficiency virus 1 envelope-specific cytotoxic T lymphocyte clones reveals a limited TCR repertoire.', J Exp Med, vol. 179, pp. 1261 - 1271, http://dx.doi.org/10.1084/jem.179.4.1261
    Journal articles | 1994
    Dr Bruce Duncan Walker
    Jassoy C; Heinkelein M; Klinker H; Walker BD, 1994, 'HIV type 1-specific cytotoxic T lymphocytes stimulate HLA class I and intercellular adhesion molecule type 1 expression and increase beta 2-microglobulin levels in vitro.', AIDS Res Hum Retroviruses, vol. 10, pp. 1685 - 1693, http://dx.doi.org/10.1089/aid.1994.10.1685
    Journal articles | 1994
    Dr Bruce Duncan Walker
    Kalams SA; Walker BD, 1994, 'The cytotoxic T-lymphocyte response in HIV-1 infection.', Clin Lab Med, vol. 14, pp. 271 - 299, https://www.ncbi.nlm.nih.gov/pubmed/7924192
    Journal articles | 1994
    Dr Bruce Duncan Walker
    Walker BD, 1994, 'The rationale for immunotherapy in HIV-1 infection.', J Acquir Immune Defic Syndr (1988), vol. 7 Suppl 1, pp. S6 - 13, https://www.ncbi.nlm.nih.gov/pubmed/8182510
    Journal articles | 1993
    Dr Bruce Duncan Walker
    Koziel MJ; Dudley D; Afdhal N; Choo QL; Houghton M; Ralston R; Walker BD, 1993, 'Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV.', J Virol, vol. 67, pp. 7522 - 7532, http://dx.doi.org/10.1128/JVI.67.12.7522-7532.1993
    Journal articles | 1993
    Dr Bruce Duncan Walker
    Johnson RP; Trocha A; Buchanan TM; Walker BD, 1993, 'Recognition of a highly conserved region of human immunodeficiency virus type 1 gp120 by an HLA-Cw4-restricted cytotoxic T-lymphocyte clone.', J Virol, vol. 67, pp. 438 - 445, http://dx.doi.org/10.1128/JVI.67.1.438-445.1993
    Journal articles | 1993
    Dr Bruce Duncan Walker
    Jassoy C; Harrer T; Rosenthal T; Navia BA; Worth J; Johnson RP; Walker BD, 1993, 'Human immunodeficiency virus type 1-specific cytotoxic T lymphocytes release gamma interferon, tumor necrosis factor alpha (TNF-alpha), and TNF-beta when they encounter their target antigens.', J Virol, vol. 67, pp. 2844 - 2852, http://dx.doi.org/10.1128/JVI.67.5.2844-2852.1993
    Journal articles | 1993
    Dr Bruce Duncan Walker
    Zweerink HJ; Gammon MC; Utz U; Sauma SY; Harrer T; Hawkins JC; Johnson RP; Sirotina A; Hermes JD; Walker BD, 1993, 'Presentation of endogenous peptides to MHC class I-restricted cytotoxic T lymphocytes in transport deletion mutant T2 cells.', J Immunol, vol. 150, pp. 1763 - 1771, https://www.ncbi.nlm.nih.gov/pubmed/7679694
    Journal articles | 1993
    Dr Bruce Duncan Walker
    Curiel TJ; Wong JT; Gorczyca PF; Schooley RT; Walker BD, 1993, 'CD4+ human immunodeficiency virus type 1 (HIV-1) envelope-specific cytotoxic T lymphocytes derived from the peripheral blood cells of an HIV-1-infected individual.', AIDS Res Hum Retroviruses, vol. 9, pp. 61 - 68, http://dx.doi.org/10.1089/aid.1993.9.61
    Journal articles | 1993
    Dr Bruce Duncan Walker
    Harrer T; Jassoy C; Harrer E; Johnson RP; Walker BD, 1993, 'Induction of HIV-1 replication in a chronically infected T-cell line by cytotoxic T lymphocytes.', J Acquir Immune Defic Syndr (1988), vol. 6, pp. 865 - 871, https://www.ncbi.nlm.nih.gov/pubmed/8315573
    Journal articles | 1992
    Dr Bruce Duncan Walker
    Jassoy C; Johnson RP; Navia BA; Worth J; Walker BD, 1992, 'Detection of a vigorous HIV-1-specific cytotoxic T lymphocyte response in cerebrospinal fluid from infected persons with AIDS dementia complex.', J Immunol, vol. 149, pp. 3113 - 3119, https://www.ncbi.nlm.nih.gov/pubmed/1383338
    Journal articles | 1992
    Dr Bruce Duncan Walker
    Zolla-Pazner S; Mathieson BJ; Walker MC; Walker B, 1992, 'Summary: Clinical Immunology Working Group.', AIDS Res Hum Retroviruses, vol. 8, pp. 1441 - 1443, http://dx.doi.org/10.1089/aid.1992.8.1441
    Journal articles | 1992
    Dr Bruce Duncan Walker
    Johnson RP; Trocha A; Buchanan TM; Walker BD, 1992, 'Identification of overlapping HLA class I-restricted cytotoxic T cell epitopes in a conserved region of the human immunodeficiency virus type 1 envelope glycoprotein: definition of minimum epitopes and analysis of the effects of sequence variation.', J Exp Med, vol. 175, pp. 961 - 971, http://dx.doi.org/10.1084/jem.175.4.961
    Journal articles | 1992
    Dr Bruce Duncan Walker
    Koziel MJ; Walker BD, 1992, 'Viruses, chemotherapy and immunity.', Parasitology, vol. 105 Suppl, pp. S85 - S92, http://dx.doi.org/10.1017/s0031182000075399
    Journal articles | 1992
    Dr Bruce Duncan Walker
    Koziel MJ; Dudley D; Wong JT; Dienstag J; Houghton M; Ralston R; Walker BD, 1992, 'Intrahepatic cytotoxic T lymphocytes specific for hepatitis C virus in persons with chronic hepatitis.', J Immunol, vol. 149, pp. 3339 - 3344, https://www.ncbi.nlm.nih.gov/pubmed/1385523
    Journal articles | 1991
    Dr Bruce Duncan Walker
    Tsomides TJ; Walker BD; Eisen HN, 1991, 'An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein.', Proc Natl Acad Sci U S A, vol. 88, pp. 11276 - 11280, http://dx.doi.org/10.1073/pnas.88.24.11276
    Journal articles | 1991
    Dr Bruce Duncan Walker
    Poznansky MC; Walker B; Haseltine WA; Sodroski J; Langhoff E, 1991, 'A rapid method for quantitating the frequency of peripheral blood cells containing HIV-1 DNA.', J Acquir Immune Defic Syndr (1988), vol. 4, pp. 368 - 373, https://www.ncbi.nlm.nih.gov/pubmed/1672549
    Journal articles | 1991
    Dr Bruce Duncan Walker
    Goldfeld AE; Birch-Limberger K; Schooley RT; Walker BD, 1991, 'HIV-1 infection does not induce tumor necrosis factor-alpha or interferon-beta gene transcription.', J Acquir Immune Defic Syndr (1988), vol. 4, pp. 41 - 47, https://www.ncbi.nlm.nih.gov/pubmed/1845771
    Journal articles | 1991
    Dr Bruce Duncan Walker
    Johnson RP; Trocha A; Yang L; Mazzara GP; Panicali DL; Buchanan TM; Walker BD, 1991, 'HIV-1 gag-specific cytotoxic T lymphocytes recognize multiple highly conserved epitopes. Fine specificity of the gag-specific response defined by using unstimulated peripheral blood mononuclear cells and cloned effector cells.', J Immunol, vol. 147, pp. 1512 - 1521, https://www.ncbi.nlm.nih.gov/pubmed/1715361
    Journal articles | 1991
    Dr Bruce Duncan Walker
    Johnson RP; Walker BD, 1991, 'Identification of HIV-1 cytotoxic T-lymphocyte epitopes and implications for vaccine development.', Biotechnol Ther, vol. 2, pp. 137 - 146, https://www.ncbi.nlm.nih.gov/pubmed/1726962
    Journal articles | 1989
    Dr Bruce Duncan Walker
    Walker BD; Flexner C; Birch-Limberger K; Fisher L; Paradis TJ; Aldovini A; Young R; Moss B; Schooley RT, 1989, 'Long-term culture and fine specificity of human cytotoxic T-lymphocyte clones reactive with human immunodeficiency virus type 1.', Proc Natl Acad Sci U S A, vol. 86, pp. 9514 - 9518, http://dx.doi.org/10.1073/pnas.86.23.9514
    Journal articles | 1989
    Dr Bruce Duncan Walker
    Johnson VA; Walker BD; Barlow MA; Paradis TJ; Chou TC; Hirsch MS, 1989, 'Synergistic inhibition of human immunodeficiency virus type 1 and type 2 replication in vitro by castanospermine and 3'-azido-3'-deoxythymidine.', Antimicrob Agents Chemother, vol. 33, pp. 53 - 57, http://dx.doi.org/10.1128/AAC.33.1.53
    Journal articles | 1989
    Dr Bruce Duncan Walker
    Johnson VA; Barlow MA; Chou TC; Fisher RA; Walker BD; Hirsch MS; Schooley RT, 1989, 'Synergistic inhibition of human immunodeficiency virus type 1 (HIV-1) replication in vitro by recombinant soluble CD4 and 3'-azido-3'-deoxythymidine.', J Infect Dis, vol. 159, pp. 837 - 844, http://dx.doi.org/10.1093/infdis/159.5.837
    Journal articles | 1988
    Dr Bruce Duncan Walker
    Walker BD; Flexner C; Paradis TJ; Fuller TC; Hirsch MS; Schooley RT; Moss B, 1988, 'HIV-1 reverse transcriptase is a target for cytotoxic T lymphocytes in infected individuals.', Science, vol. 240, pp. 64 - 66, http://dx.doi.org/10.1126/science.2451288
    Journal articles | 1988
    Dr Bruce Duncan Walker
    Fisher RA; Bertonis JM; Meier W; Johnson VA; Costopoulos DS; Liu T; Tizard R; Walker BD; Hirsch MS; Schooley RT, 1988, 'HIV infection is blocked in vitro by recombinant soluble CD4.', Nature, vol. 331, pp. 76 - 78, http://dx.doi.org/10.1038/331076a0
    Journal articles | 1988
    Dr Bruce Duncan Walker
    Hussey RE; Richardson NE; Kowalski M; Brown NR; Chang HC; Siliciano RF; Dorfman T; Walker B; Sodroski J; Reinherz EL, 1988, 'A soluble CD4 protein selectively inhibits HIV replication and syncytium formation.', Nature, vol. 331, pp. 78 - 81, http://dx.doi.org/10.1038/331078a0
    Journal articles | 1987
    Dr Bruce Duncan Walker
    Walker BD; Kowalski M; Goh WC; Kozarsky K; Krieger M; Rosen C; Rohrschneider L; Haseltine WA; Sodroski J, 1987, 'Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine.', Proc Natl Acad Sci U S A, vol. 84, pp. 8120 - 8124, http://dx.doi.org/10.1073/pnas.84.22.8120
    Journal articles | 1987
    Dr Bruce Duncan Walker
    Walker BD; Chakrabarti S; Moss B; Paradis TJ; Flynn T; Durno AG; Blumberg RS; Kaplan JC; Hirsch MS; Schooley RT, 1987, 'HIV-specific cytotoxic T lymphocytes in seropositive individuals.', Nature, vol. 328, pp. 345 - 348, http://dx.doi.org/10.1038/328345a0
  • Conference Papers | 2001
    Dr Bruce Duncan Walker
    Walker BD; Tie H; Singleton CB; Bursill JA; Wyse KR; Bauskin AR; Valenzuela SM; Wu W; Breit SN; Campbell TJ, 2001, 'Modification of HERG channel properties under conditions of simulated myocardial ischemia', in JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ELSEVIER SCIENCE INC, pp. 114A - 115A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000166914400526&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1999
    Dr Bruce Duncan Walker
    Singleton CB; Walker BD; Bursill JA; Wyse KR; Valenzuela SM; Breit SN; Campbell TJ, 1999, 'Potential cellular mechanism for the antifibrillatory properties of fish oils: potent blockade of the Kv4.3 current (Ito)', in Circulation, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. I-279 - I-279, presented at 72nd Scientific Session Conference, Atlanta, Georgia USA, 07 November 1999 - 10 November 1999, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000083417101457&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 1999
    Dr Bruce Duncan Walker
    Tie H; Valenzuela SM; Walker BD; Singleton CB; Bursill JA; Wyse KR; Breit SN; Campbell TJ, 1999, 'Blockade of the human ether-a-go-go-related gene (HERG) potassium channel by amitriptyline: Another mechanism for cardiotoxicity', in European Heart Journal, W B Saunders Company Ltd, London, England, pp. 329 - 329, presented at European Society of Cardiology, Barcelona, Spain
    Conference Papers | 1999
    Dr Bruce Duncan Walker
    Singleton CB; Walker BD; Campbell TJ, 1999, 'Modulation of antiarrhythmic actions by myocardial ischaemia', in Proceedings of the Australian Physiological and Pharmacological Society, 67th Meeting of Physiology and Pharmacology Society, University of Newcastle, NSW, pp. 125P - 125P, presented at 67th Meeting of Physiology and Pharmacology Society, University of Newcastle, NSW, 27 September 1999 - 29 September 1999
    Visual Arts | 1999
    Dr Bruce Duncan Walker
    Walker BD, 1999, Exhibited: Sydney printmakers, Australia at , publication category: Visual Arts
    Visual Arts | 1999
    Dr Bruce Duncan Walker
    Walker BD, 1999, Exhibited: 4 ways` quadrivium at , publication category: Visual Arts
    Conference Papers | 1999
    Dr Bruce Duncan Walker
    Singleton CB; Walker BD; Tie H; Wyse KR; Bursill JA; Valenzuela SM; Qui MR; Breit SN; Campbell TJ, 1999, 'Potential cellular mechanism for the antifibrillatory properties of fish oils: potent blockade of the Kv4.3 encoded transient outward current.', in European Heart Journal, W B Saunders Company Ltd, London, England, pp. 575 - 575, presented at European Society of Cardiology, Barcelona, Spain, -
    Conference Papers | 1998
    Dr Bruce Duncan Walker
    Walker BD; Singleton CB; Bursill JA; Wyse KR; Dwyer L; Qui MR; Valenzuela SM; Breit SN; Campbell TJ, 1998, 'Perhexiline maleate inhibits the rapidly activating cardiac delayed rectifier potassium channel (IKr) in rabbit ventricular myocytes and the human ether-a-go-go-related gene (HERG) potassium current', in Australian and New Zealand Journal of Medicine, Adis International Limited, Frenchs Forest, NSW, pp. 120 - 120, presented at Annual Scientific Meeting of Cardiac Soc. Aust. and N.Z, Perth, WA, 02 August 1998 - 05 August 1998
    Conference Papers | 1998
    Dr Bruce Duncan Walker
    Walker BD; Singleton CB; Bursill JA; Wyse KR; Dwyer L; Qui MR; Valenzuela SM; Breit SN; Campbell TJ, 1998, 'Cisapride inhibits the human ether-a-go-go-related gene (HERG), potassium channel expressed in Chinese hamster ovary (CHO-K1) cells', in Australian and New Zealand Journal of Medicine, Adis International Limited, Frenchs Forest, NSW, pp. 120 - 120, presented at Annual Scientific Meeting of Cardiac Soc. Aust. and N.Z, Perth, WA, 02 August 1998 - 05 August 1998
    Conference Papers | 1998
    Dr Bruce Duncan Walker
    Singleton CB; Walker BD; Bursill JA; Wyse KR; Dwyer L; Qui MR; Valenzuela SM; Breit SN; Campbell TJ, 1998, 'Characterisation of the Kv4.3 encoded human transient outward current and its inhibition by an omega-3 fatty acid.', in Australian and New Zealand Journal of Medicine, Adis International Limited, Frenchs Forest, NSW, pp. 153 - 153, presented at Annual Scientific Meeting of Cardiac Soc. Aust. and N.Z, Perth, WA, 02 August 1998 - 05 August 1998

Awards

Grants

Media