Adjunct Professor

Associate Professor David Brown

Medicine & Health
School of Clinical Medicine

Research Interests:
In the field of inflammation I have clinical and research interests. Clinically, I am interested in the consequences of inflammatory diseases on the CNS, vasculitides as well as treatment of connective tissue diseases. My research interests are in several areas including chronic inflammatory diseases such as atherosclerosis and rheumatoid arthritis. I am also actively researching the role of the immunity in cancer and neuroinflammatory diseases.

Broad Research Areas:
Inflammation, Neuroscience, Immunology, Pathology

Qualifications:
MBBS (Hons), PhD, FRACP, FRCPA

Specific Research Keywords:
T Cells, Cytokines, Neuroimmunology, Autoimmune Disease, Stem Cell Therapy

Phone
02 8382 4952
  • Books | 2020
    Brown DA, 2020, Neurons, receptors, and channels, http://dx.doi.org/10.1146/annurev-pharmtox-010919-023755
  • Book Chapters | 2016
    Breit SN; Brown DA, 2016, 'TGF beta Superfamily Cytokine MIC-1/GDF15 in Health and Inflammatory Diseases', in Compendium of Inflammatory Diseases, Springer Basel, pp. 1236 - 1245, http://dx.doi.org/10.1007/978-3-7643-8550-7_54
    Book Chapters | 2014
    Breit SN; Brown DA, 2014, 'TGF-b Superfamily Cytokine MIC-1/GDF15 in Health and Inflammatory Diseases', in Encyclopedia of Inflammatory Diseases, Springer Basel, pp. 1 - 13, http://dx.doi.org/10.1007/978-3-0348-0620-6_54-1
    Book Chapters | 2014
    Brown DA; Bauskin AR; Breit SN, 2014, 'MIC-1', in Encyclopedia of Cancer, Springer Berlin Heidelberg, pp. 1 - 6, http://dx.doi.org/10.1007/978-3-642-27841-9_3704-2
    Book Chapters | 2014
    Brown DA; Bauskin AR; Breit SN, 2014, 'MIC-1', in Encyclopedia of Cancer, Springer Berlin Heidelberg, pp. 2816 - 2821, http://dx.doi.org/10.1007/978-3-662-46875-3_3704
    Book Chapters | 2011
    Brown DA; Breit SN; Bauskin AR, 2011, 'MIC-1', in Encyclopedia of Cancer, Springer Berlin Heidelberg, pp. 2285 - 2289, http://dx.doi.org/10.1007/978-3-642-16483-5_3704
    Book Chapters |
    Bauskin AR; Brown DA; Breit SN, 'MIC-1', in Encyclopedia of Cancer, Springer Berlin Heidelberg, pp. 1870 - 1873, http://dx.doi.org/10.1007/978-3-540-47648-1_3704
  • Journal articles | 2022
    Kakar F; Swaminathan S; Brown DA; Lin M-W; McDonald D; Lee AYS, 2022, 'Corrigendum to "Restricted migration of polyclonal IgG on immunofixation gel electrophoresis in a case of IgG4-related disease" [Pathology 54 (2022) 367-369].', Pathology, vol. 54, pp. 668, http://dx.doi.org/10.1016/j.pathol.2022.05.001
    Journal articles | 2022
    Kakar F; Swaminathan S; Brown DA; Lin MW; McDonald D; Lee AYS, 2022, 'Restricted migration of polyclonal IgG on immunofixation gel electrophoresis in a case of IgG4-related disease', Pathology, vol. 54, pp. 367 - 369, http://dx.doi.org/10.1016/j.pathol.2021.05.092
    Journal articles | 2022
    Lee AYS; Brown DA; McDonald D; Lin MW, 2022, 'Longitudinal Tracking of Extractable Nuclear Antigen (ENA) Antibodies in a Quaternary Hospital Laboratory Cohort Reveals Dynamic Antibody Profiles', The journal of applied laboratory medicine, vol. 7, pp. 26 - 35, http://dx.doi.org/10.1093/jalm/jfab104
    Journal articles | 2022
    Lee AYS; Lee C; Brown DA; Suan D, 2022, 'Development of anti-NXP2 dermatomyositis following Comirnaty COVID-19 vaccination.', Postgrad Med J, http://dx.doi.org/10.1136/postgradmedj-2022-141510
    Journal articles | 2022
    Lopez JA; Houston SD; Tea F; Merheb V; Lee FXZ; Smith S; McDonald D; Zou A; Liyanage G; Pilli D; Denkova M; Lechner-Scott J; van der Walt A; Barnett MH; Reddel SW; Broadley S; Ramanathan S; Dale RC; Brown DA; Brilot F, 2022, 'Validation of a Flow Cytometry Live Cell-Based Assay to Detect Myelin Oligodendrocyte Glycoprotein Antibodies for Clinical Diagnostics', The journal of applied laboratory medicine, vol. 7, pp. 12 - 25, http://dx.doi.org/10.1093/jalm/jfab101
    Journal articles | 2022
    Zammit NW; McDowell J; Warren J; Muskovic W; Gamble J; Shi YC; Kaczorowski D; Chan CL; Powell J; Ormandy C; Brown D; Oakes SR; Grey ST, 2022, 'TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation', Frontiers in Immunology, vol. 13, http://dx.doi.org/10.3389/fimmu.2022.811525
    Journal articles | 2021
    Breit SN; Brown DA; Tsai VWW, 2021, 'The GDF15-GFRAL Pathway in Health and Metabolic Disease: Friend or Foe?', Annual Review of Physiology, vol. 83, pp. 127 - 151, http://dx.doi.org/10.1146/annurev-physiol-022020-045449
    Journal articles | 2021
    Gardner LS; Culican S; Campbell D; Dela Cruz M; McDonald D; Brown DA; Lin MW, 2021, 'Internal audit of two antineuronal immunoblots and the role of indirect immunofluorescence in sample screening', Pathology, vol. 53, pp. S48 - S48, http://dx.doi.org/10.1016/j.pathol.2021.06.101
    Journal articles | 2021
    Law SPL; Gatt PN; Schibeci SD; McKay FC; Vucic S; Hart P; Byrne SN; Brown D; Stewart GJ; Liddle C; Parnell GP; Booth DR, 2021, 'Expression of CYP24A1 and other multiple sclerosis risk genes in peripheral blood indicates response to vitamin D in homeostatic and inflammatory conditions', Genes and Immunity, vol. 22, pp. 227 - 233, http://dx.doi.org/10.1038/s41435-021-00144-6
    Journal articles | 2021
    Tea F; Stella AO; Aggarwal A; Darley DR; Pilli D; Vitale D; Merheb V; Lee FXZ; Cunningham P; Walker GJ; Fichter C; Brown DA; Rawlinson WD; Isaacs SR; Mathivanan V; Hoffmann M; Pöhlman S; Mazigi O; Christ D; Rockett RJ; Sintchenko V; Hoad VC; Irving DO; Dore GJ; Gosbell IB; Kelleher AD; Matthews GV; Brilot F; Turville SG, 2021, 'SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants', PLoS Medicine, vol. 18, http://dx.doi.org/10.1371/journal.pmed.1003656
    Journal articles | 2021
    Trend S; Leffler J; Jones AP; Cha L; Gorman S; Brown DA; Breit SN; Kermode AG; French MA; Ward NC; Hart PH, 2021, 'Associations of serum short-chain fatty acids with circulating immune cells and serum biomarkers in patients with multiple sclerosis', Scientific Reports, vol. 11, pp. 5244, http://dx.doi.org/10.1038/s41598-021-84881-8
    Journal articles | 2021
    Wu L; Tsang VHM; Sasson SC; Menzies AM; Carlino MS; Brown DA; Clifton-Bligh R; Gunton JE, 2021, 'Unravelling Checkpoint Inhibitor Associated Autoimmune Diabetes: From Bench to Bedside', Frontiers in Endocrinology, vol. 12, http://dx.doi.org/10.3389/fendo.2021.764138
    Journal articles | 2020
    Dai P; Campbell D; Culican S; Brown DA; Byth K; Hissaria P; Ninnes R; Nankivell B; Lin MW, 2020, 'Validation of phospholipase A2 receptor direct immunofluorescence staining in the diagnosis of primary membranous glomerulonephritis', Pathology, vol. 52, pp. 546 - 551, http://dx.doi.org/10.1016/j.pathol.2020.04.003
    Journal articles | 2020
    Husaini Y; Tsai VWW; Manandhar R; Zhang HP; Lee-Ng KKM; Lebhar H; Marquis CP; Brown DA; Breit SN, 2020, 'Growth differentiation factor-15 slows the growth of murine prostate cancer by stimulating tumor immunity', PLoS ONE, vol. 15, pp. e0233846, http://dx.doi.org/10.1371/journal.pone.0233846
    Journal articles | 2020
    Jiang JX; Fewings N; Dervish S; Fois AF; Duma SR; Silsby M; Bandodkar S; Ramanathan S; Bleasel A; John B; Brown DA; Lin MW, 2020, 'Novel Surrogate Markers of CNS Inflammation in CSF in the Diagnosis of Autoimmune Encephalitis', Frontiers in Neurology, vol. 10, http://dx.doi.org/10.3389/fneur.2019.01390
    Journal articles | 2020
    Pollak TA; Lennox BR; Müller S; Benros ME; Prüss H; Tebartz van Elst L; Klein H; Steiner J; Frodl T; Bogerts B; Tian L; Groc L; Hasan A; Baune BT; Endres D; Haroon E; Yolken R; Benedetti F; Halaris A; Meyer JH; Stassen H; Leboyer M; Fuchs D; Otto M; Brown DA; Vincent A; Najjar S; Bechter K, 2020, 'Autoimmune psychosis: an international consensus on an approach to the diagnosis and management of psychosis of suspected autoimmune origin', The Lancet Psychiatry, vol. 7, pp. 93 - 108, http://dx.doi.org/10.1016/S2215-0366(19)30290-1
    Journal articles | 2020
    Tea F; Pilli D; Ramanathan S; Lopez JA; Merheb V; Lee FXZ; Zou A; Liyanage G; Bassett CB; Thomsen S; Reddel SW; Barnett MH; Brown DA; Dale RC; Brilot F, 2020, 'Effects of the Positive Threshold and Data Analysis on Human MOG Antibody Detection by Live Flow Cytometry', Frontiers in Immunology, vol. 11, http://dx.doi.org/10.3389/fimmu.2020.00119
    Journal articles | 2019
    Afrasiabi A; Parnell GP; Fewings N; Schibeci SD; Basuki MA; Chandramohan R; Zhou Y; Taylor B; Brown DA; Swaminathan S; McKay FC; Stewart GJ; Booth DR, 2019, 'Evidence from genome wide association studies implicates reduced control of Epstein-Barr virus infection in multiple sclerosis susceptibility', Genome Medicine, vol. 11, pp. 26, http://dx.doi.org/10.1186/s13073-019-0640-z
    Journal articles | 2019
    Bayly A; Dear L; Brown D; Nankivell B; Viswanathan S, 2019, '53. Monoclonal gammopathies affecting the kidney', Pathology, vol. 51, pp. S164 - S165, http://dx.doi.org/10.1016/j.pathol.2018.09.051
    Journal articles | 2019
    Bechter K; Brown D; Najjar S, 2019, 'Editorial: Recent advances in psychiatry from psycho-neuro-immunology research: Autoimmune encephalitis, autoimmune encephalopathy, and mild encephalitis', Frontiers in Psychiatry, vol. 10, http://dx.doi.org/10.3389/fpsyt.2019.00169
    Journal articles | 2019
    Hassanpour Golakani M; Mohammad MG; Li H; Gamble J; Breit SN; Ruitenberg MJ; Brown DA, 2019, 'MIC-1/GDF15 Overexpression Is Associated with Increased Functional Recovery in Traumatic Spinal Cord Injury', Journal of Neurotrauma, vol. 36, pp. 3410 - 3421, http://dx.doi.org/10.1089/neu.2019.6421
    Journal articles | 2019
    Parnell GP; Schibeci SD; Fewings NL; Afrasiabi A; Law SPL; Samaranayake S; Kh'Ng JH; Fong YH; Brown DA; Liddle C; Stewart GJ; Booth DR, 2019, 'The latitude-dependent autoimmune disease risk genes ZMIZ1 and IRF8 regulate mononuclear phagocytic cell differentiation in response to Vitamin D', Human Molecular Genetics, vol. 28, pp. 269 - 278, http://dx.doi.org/10.1093/hmg/ddy324
    Journal articles | 2019
    Ramanathan S; O'grady GL; Malone S; Spooner CG; Brown DA; Gill D; Brilot F; Dale RC, 2019, 'Isolated seizures during the first episode of relapsing myelin oligodendrocyte glycoprotein antibody-associated demyelination in children', Developmental Medicine and Child Neurology, vol. 61, pp. 610 - 614, http://dx.doi.org/10.1111/dmcn.14032
    Journal articles | 2019
    Tea F; Lopez JA; Ramanathan S; Merheb V; Lee FXZ; Zou A; Pilli D; Patrick E; van der Walt A; Monif M; Tantsis EM; Yiu EM; Vucic S; Henderson APD; Fok A; Fraser CL; Lechner-Scott J; Reddel SW; Broadley S; Barnett MH; Brown DA; Lunemann JD; Dale RC; Brilot F; Sinclair A; Kermode AG; Kornberg A; Bye A; McGettigan B; Trewin B; Brew B; Taylor B; Bundell C; Miteff C; Troedson C; Pridmore C; Spooner C; Yiannikas C; O'Gorman C; Clark D; Suan D; Jones D; Kilfoyle D; Gill D; Wakefield D; Hofmann D; Mathey E; O'Grady G; Jones HF; Beadnall H; Butzkueven H; Joshi H; Andrews I; Sutton I; MacIntyre J; Sandbach JM; Freeman J; King J; O'Neill JH; Parratt J; Barton J; Garber J; Ahmad K; Riney K; Buzzard K; Kothur K; Cantrill LC; Menezes MP; Paine MA; Marriot M; Ghadiri M; Boggild M; Lawlor M; Badve M; Ryan M; Aaqib M; Shuey N; Jordan N; Urriola N; Lawn N; White O; McCombe P; Patel R; Leventer R; Webster R; Smith R; Gupta S; Mohammad SS; Pillai S; Hawke S; Simon S; Calvert S; Blum S; Malone S; Hodgkinson S; Nguyen TK; Hardy TA; Kalincik T; Ware T; Fung VSC, 2019, 'Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelination', Acta Neuropathologica Communications, vol. 7, http://dx.doi.org/10.1186/s40478-019-0786-3
    Journal articles | 2019
    Tsai VWW; Zhang HP; Manandhar R; Schofield P; Christ D; Lee-Ng KKM; Lebhar H; Marquis CP; Husaini Y; Brown DA; Breit SN, 2019, 'GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS', International Journal of Obesity, vol. 43, pp. 2370 - 2380, http://dx.doi.org/10.1038/s41366-019-0365-5
    Journal articles | 2018
    Brown DA, 2018, 'Current and emerging diagnostic approaches to identify autoimmune contribution to psychiatric disease', Neurology, Psychiatry and Brain Research, vol. 29, pp. 6 - 6, http://dx.doi.org/10.1016/j.npbr.2018.01.061
    Journal articles | 2018
    Brown DA; Jiang J; Ramanathan S; Silvestrini R; Bleasel A; Wienholt L; Fewings N; Dumas S; Silsby M; Yin K; Fois A; Lin M-W, 2018, 'Potential surrogate markers of central nervous system inflammation in cerebrospinal fluid in the diagnosis of autoimmune encephalitis', Neurology, Psychiatry and Brain Research, vol. 29, pp. 6 - 7, http://dx.doi.org/10.1016/j.npbr.2018.01.062
    Journal articles | 2018
    Dai P; Campbell D; Culican S; McDonald D; Hissaria P; Ninnes R; Brown D; Lin M-W, 2018, 'Validation of renal biopsy phospholipase A2 receptor staining on direct immunofluorescence in the diagnosis of primary membranous glomerulonephritis', Pathology, vol. 50, pp. S43 - S43, http://dx.doi.org/10.1016/j.pathol.2017.12.099
    Journal articles | 2018
    Jiang J; Thalamuthu A; Ho JE; Mahajan A; Ek WE; Brown DA; Breit SN; Wang TJ; Gyllensten U; Chen MH; Enroth S; Januzzi JL; Lind L; Armstrong NJ; Kwok JB; Schofield PR; Wen W; Trollor JN; Johansson Å; Morris AP; Vasan RS; Sachdev PS; Mather KA, 2018, 'A meta-analysis of genome-wide association studies of growth differentiation factor-15 concentration in blood', Frontiers in Genetics, vol. 9, http://dx.doi.org/10.3389/fgene.2018.00097
    Journal articles | 2018
    Jiang JX; Ramanathan S; Silvestrini R; Bleasel A; Wienholt L; Fewings N; Duma S; Silsby M; Yin K; Fois AF; Brown DA; Lin M-W, 2018, 'Potential surrogate markers of central nervous system inflammation in cerebrospinal fluid in the diagnosis of autoimmune encephalitis', Pathology, vol. 50, pp. S43 - S43, http://dx.doi.org/10.1016/j.pathol.2017.12.100
    Journal articles | 2018
    Ting YS; Smith SABC; Brown DA; Dodds AJ; Fay KC; Ma DDF; Milliken S; Moore JJ; Sewell WA, 2018, 'CD200 is a useful diagnostic marker for identifying atypical chronic lymphocytic leukemia by flow cytometry', International Journal of Laboratory Hematology, vol. 40, pp. 533 - 539, http://dx.doi.org/10.1111/ijlh.12857
    Journal articles | 2018
    Tsai VW; Zhang HP; Manandhar R; Lee-Ng KKM; Lebhar H; Marquis CP; Husaini Y; Sainsbury A; Brown DA; Breit SN, 2018, 'Treatment with the TGF-b superfamily cytokine MIC-1/GDF15 reduces the adiposity and corrects the metabolic dysfunction of mice with diet-induced obesity', International Journal of Obesity, vol. 42, pp. 561 - 571, http://dx.doi.org/10.1038/ijo.2017.258
    Journal articles | 2018
    Tsai VWW; Brown DA; Breit SN, 2018, 'Targeting the divergent TGFb superfamily cytokine MIC-1/GDF15 for therapy of anorexia/ cachexia syndromes', Current Opinion in Supportive and Palliative Care, vol. 12, pp. 404 - 409, http://dx.doi.org/10.1097/SPC.0000000000000384
    Journal articles | 2018
    Tsai VWW; Husaini Y; Sainsbury A; Brown DA; Breit SN, 2018, 'The MIC-1/GDF15-GFRAL Pathway in Energy Homeostasis: Implications for Obesity, Cachexia, and Other Associated Diseases', Cell Metabolism, vol. 28, pp. 353 - 368, http://dx.doi.org/10.1016/j.cmet.2018.07.018
    Journal articles | 2017
    Breit SN; Tsai VWW; Brown DA, 2017, 'Targeting Obesity and Cachexia: Identification of the GFRAL Receptor–MIC-1/GDF15 Pathway', Trends in Molecular Medicine, vol. 23, pp. 1065 - 1067, http://dx.doi.org/10.1016/j.molmed.2017.10.005
    Journal articles | 2017
    Danta M; Barber DA; Zhang HP; Lee-Ng M; Baumgart SWL; Tsai VWW; Husaini Y; Saxena M; Marquis CP; Errington W; Kerr S; Breit SN; Brown DA, 2017, 'Macrophage inhibitory cytokine-1/growth differentiation factor-15 as a predictor of colonic neoplasia', Alimentary Pharmacology and Therapeutics, vol. 46, pp. 347 - 354, http://dx.doi.org/10.1111/apt.14156
    Journal articles | 2017
    Glass LJ; Sinclair D; Boerrigter D; Naude K; Fung SJ; Brown D; Catts VS; Tooney P; O'Donnell M; Lenroot R; Galletly C; Liu D; Weickert TW; Shannon Weickert C, 2017, 'Brain antibodies in the cortex and blood of people with schizophrenia and controls', Translational Psychiatry, vol. 7, http://dx.doi.org/10.1038/tp.2017.134
    Journal articles | 2017
    Low JK; Ambikairajah A; Shang K; Brown DA; Tsai VWW; Breit SN; Karl T, 2017, 'First behavioural characterisation of a knockout mouse model for the transforming growth factor (TGF)-β superfamily cytokine, MIC-1/GDF15', PLoS ONE, vol. 12, http://dx.doi.org/10.1371/journal.pone.0168416
    Journal articles | 2017
    Ong LTC; Galambos G; Brown DA, 2017, 'Primary Sjogren's syndrome associated with treatment-resistant obsessive-compulsive Disorder', Frontiers in Psychiatry, vol. 8, http://dx.doi.org/10.3389/fpsyt.2017.00124
    Journal articles | 2017
    P'ng CH; Dear L; Phoon R; Brown D, 2017, 'A rare case of concurrent myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)-associated necrotising and crescentic glomerulonephritis and membranous glomerulonephritis', Pathology, vol. 49, pp. 100 - 103, http://dx.doi.org/10.1016/j.pathol.2016.10.008
    Journal articles | 2017
    Tran DN; Smith SABC; Brown DA; Parker AJC; Joseph JE; Armstrong N; Sewell WA, 2017, 'Polychromatic flow cytometry is more sensitive than microscopy in detecting small monoclonal plasma cell populations', Cytometry Part B - Clinical Cytometry, vol. 92, pp. 136 - 144, http://dx.doi.org/10.1002/cyto.b.21401
    Journal articles | 2016
    Brown DA, 2016, 'Glycine receptor antibodies in psychiatric and neurological disease', Neurology, Psychiatry and Brain Research, vol. 22, pp. 4 - 4, http://dx.doi.org/10.1016/j.npbr.2015.12.010
    Journal articles | 2016
    Mahon KL; Lin H-M; Spielman C; Lee-Ng M; Gurney H; Mallesara G; Stockler MR; Briscoe KP; Marx GM; Breit SN; Brown DA; Horvath L, 2016, 'Phase II trial of circulating cytokines as markers of docetaxel (DTX) resistance in metastatic castrate-resistant prostate cancer (mCRPC).', Journal of Clinical Oncology, vol. 34, pp. 5039 - 5039, http://dx.doi.org/10.1200/jco.2016.34.15_suppl.5039
    Journal articles | 2016
    Salao K; Jiang L; Li H; Tsai VWW; Husaini Y; Curmi PMG; Brown LJ; Brown DA; Breit SN, 2016, 'CLIC1 regulates dendritic cell antigen processing and presentation by modulating phagosome acidification and proteolysis', Biology Open, vol. 5, pp. 620 - 630, http://dx.doi.org/10.1242/bio.018119
    Journal articles | 2016
    Tsai VWW; Lin S; Brown DA; Salis A; Breit SN, 2016, 'Anorexia-cachexia and obesity treatment may be two sides of the same coin: Role of the TGF-b superfamily cytokine MIC-1/GDF15', International Journal of Obesity, vol. 40, pp. 193 - 197, http://dx.doi.org/10.1038/ijo.2015.242
    Journal articles | 2015
    Fisher OM; Levert-Mignon AJ; Lord SJ; Lee-Ng KKM; Botelho NK; Falkenback D; Thomas ML; Bobryshev YV; Whiteman DC; Brown DA; Breit SN; Lord RV, 2015, 'MIC-1/GDF15 in Barrett's oesophagus and oesophageal adenocarcinoma', British Journal of Cancer, vol. 112, pp. 1384 - 1391, http://dx.doi.org/10.1038/bjc.2015.100
    Journal articles | 2015
    Husaini Y; Lockwood GP; Nguyen TV; Tsai VWW; Mohammad MG; Russell PJ; Brown DA; Breit SN, 2015, 'Macrophage inhibitory cytokine-1 (MIC-1/GDF15) gene deletion promotes cancer growth in TRAMP prostate cancer prone mice', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0115189
    Journal articles | 2015
    Jiang J; Trollor JN; Brown DA; Crawford JD; Thalamuthu A; Smith E; Breit SN; Liu T; Brodaty H; Baune BT; Sachdev PS; Wen W, 2015, 'An inverse relationship between serum macrophage inhibitory cytokine-1 levels and brain white matter integrity incommunity-dwelling older individuals', Psychoneuroendocrinology, vol. 62, pp. 80 - 88, http://dx.doi.org/10.1016/j.psyneuen.2015.07.610
    Journal articles | 2015
    Jiang J; Wen W; Brown DA; Crawford J; Thalamuthu A; Smith E; Breit SN; Liu T; Zhu W; Brodaty H; Baune BT; Trollor JN; Sachdev PS, 2015, 'The relationship of serum macrophage inhibitory cytokine - 1 levels with gray matter volumes in community-dwelling older individuals', PLoS ONE, vol. 10, pp. e0123399, http://dx.doi.org/10.1371/journal.pone.0123399
    Journal articles | 2015
    Jones SP; Franco NF; Varney B; Sundaram G; Brown DA; De Bie J; Lim CK; Guillemin GJ; Brew BJ, 2015, 'Expression of the kynurenine pathway in human peripheral blood mononuclear cells: Implications for inflammatory and neurodegenerative disease', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0131389
    Journal articles | 2015
    Mahon KL; Lin HM; Castillo L; Lee BY; Lee-Ng M; Chatfield MD; Chiam K; Breit SN; Brown DA; Molloy MP; Marx GM; Pavlakis N; Boyer MJ; Stockler MR; Daly RJ; Henshall SM; Horvath LG, 2015, 'Cytokine profiling of docetaxel-resistant castration-resistant prostate cancer', British Journal of Cancer, vol. 112, pp. 1340 - 1348, http://dx.doi.org/10.1038/bjc.2015.74
    Journal articles | 2015
    Sasson SC; McGill K; Wienholt L; Carr A; Brown D; Kelleher AD; Breit SN; Sewell WA, 2015, 'Retrospective audit of the freeliteTM serum free light chain (SFLC) assay: testing patterns, concordance with serum and urine electrophoresis/immunofixation and correlation with the N latex FLC assay', Pathology, vol. 47, pp. S94 - S94, http://dx.doi.org/10.1097/01.pat.0000461601.28805.d5
    Journal articles | 2015
    Sasson SC; McGill K; Wienholt L; Carr A; Brown DA; Kelleher AD; Breit SN; Sewell WA, 2015, 'Comparison of the Freelite serum free light chain (SFLC) assay with serum and urine electrophoresis/immunofixation and the N Latex FLC assay', Pathology, vol. 47, pp. 564 - 569, http://dx.doi.org/10.1097/PAT.0000000000000316
    Journal articles | 2015
    Tran D; Smith S; Brown D; Sewell W, 2015, 'Immunophenotyping of plasma cell and the utility of flow cytometry in plasma cell dyscrasias', Pathology, vol. 47, pp. S94 - S95, http://dx.doi.org/10.1097/01.pat.0000461602.22967.40
    Journal articles | 2015
    Tsai VWW; Macia L; Feinle-Bisset C; Manandhar R; Astrup A; Raben A; Lorenzen JK; Schmidt PT; Wiklund F; Pedersen NL; Campbell L; Kriketos A; Xu A; Pengcheng Z; Jia W; Curmi PMG; Angstmann CN; Lee-Ng KKM; Zhang HP; Marquis CP; Husaini Y; Beglinger C; Lin S; Herzog H; Brown DA; Sainsbury A; Breit SN, 2015, 'Serum levels of human MIC-1/GDF15 vary in a diurnal pattern, do not display a profile suggestive of a satiety factor and are related to BMI', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0133362
    Journal articles | 2014
    Fuchs T; Trollor JN; Crawford J; Baune BT; Samaras K; Campbell L; Breit SN; Brodaty H; Sachdev P; Smith E; Brown DA, 2014, 'Macrophage inhibitory cytokine-1 is associated with cognitive impairment and predicts cognitive decline – The Sydney Memory and Aging Study', Neurology, Psychiatry and Brain Research, vol. 20, pp. 9 - 9, http://dx.doi.org/10.1016/j.npbr.2014.01.145
    Journal articles | 2014
    Mohammad MG; Tsai VWW; Ruitenberg MJ; Hassanpour M; Li H; Hart PH; Breit SN; Sawchenko PE; Brown DA, 2014, 'A forebrain-immune cell pathway for the maintenance of CNS immune tolerance', Neurology, Psychiatry and Brain Research, vol. 20, pp. 8 - 9, http://dx.doi.org/10.1016/j.npbr.2014.01.144
    Journal articles | 2014
    Mohammad MG; Tsai VWW; Ruitenberg MJ; Hassanpour M; Li H; Hart PH; Breit SN; Sawchenko PE; Brown DA, 2014, 'Immune cell trafficking from the brain maintains CNS immune tolerance', Journal of Clinical Investigation, vol. 124, pp. 1228 - 1241, http://dx.doi.org/10.1172/JCI71544
    Journal articles | 2014
    Tsai VW-W; Macia L; Manandhar R; Wiklund F; Grönberg H; Pedersen N; Lee-Ng M; Zhang HP; Brown D; Herzog H; Sainsbury A; Breit SN, 2014, 'Macrophage inhibitory cytokine 1 (MIC-1/GDF15), a novel regulator of body weight and appetite and a potential therapeutic for obesity', Obesity Research & Clinical Practice, vol. 8, pp. 105 - 105, http://dx.doi.org/10.1016/j.orcp.2014.10.191
    Journal articles | 2014
    Tsai VWW; Manandhar R; Jrøgensen SB; Lee-Ng KKM; Zhang HP; Marquis CP; Jiang L; Husaini Y; Lin S; Sainsbury A; Sawchenko PE; Brown DA; Breit SN, 2014, 'The anorectic actions of the TGFβ cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract', PLoS ONE, vol. 9, http://dx.doi.org/10.1371/journal.pone.0100370
    Journal articles | 2013
    Bechter K; Brown D, 2013, 'Neuroinflammation in psychiatric disorders - Evidence from research and clinic', Neurology Psychiatry and Brain Research, vol. 19, pp. 139 - 140, http://dx.doi.org/10.1016/j.npbr.2013.12.001
    Journal articles | 2013
    Fuchs T; Trollor JN; Crawford J; Baune BT; Samaras K; Campbell L; Breit SN; Brodaty H; Sachdev P; Smith E, 2013, 'Macrophage inhibitory cytokine-1 is associated with cognitive impairment and predicts cognitive decline – the Sydney Memory and Ageing Study', Aging Cell, vol. 12, pp. 882 - 889, http://dx.doi.org/10.1111/acel.12116
    Journal articles | 2013
    Horvath L; Chatfield MD; Lee-Ng M; Lin H-M; Castillo L; Breit SN; Brown DA; Molloy MP; Marx GM; Pavlakis N; Boyer MJ; Stockler MR; Wykes R; Henshall SM; Mahon KL, 2013, 'The role of macrophages in docetaxel (DTX) resistance in castrate-resistant prostate cancer (CRPC).', Journal of Clinical Oncology, vol. 31, pp. e22175 - e22175, http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e22175
    Journal articles | 2013
    Mohammad MG; Hassanpour M; Tsai VW-W; Li H; Ruitenberg MJ; Booth D; Serrats J; Hart PH; Symonds GP; Sawchenko P; Breit SN; Brown DA, 2013, 'Dendritic cells and multiple sclerosis: Disease, tolerance and therapy', International Journal of Molecular Sciences, vol. 14, pp. 547 - 562, http://dx.doi.org/10.3390/ijms14010547
    Journal articles | 2012
    Breit SN; Carrero JJ; Tsai VWW; Yagoutifam N; Luo XW; Kuffner T; Bauskin AR; Wu L; Jiang L; Baranyi P; Heimburer O; Murikami M; Apple F; Marquis C; Macia L; Lin S; Sainsbury-Salis A; Herzog H; Law MG; Stenvinkel P; Brown DA, 2012, 'Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease', Nephrology Dialysis Transplantation, vol. 27, pp. 70 - 75, http://dx.doi.org/10.1093/ndt/gfr575
    Journal articles | 2012
    Brown D; Hance KW; Rogers C; Sansbury ; Albert P; Murphy G; Laiyemo A; Wang Z; Cross A; Schatzkin A; Danta M; Srasu ; Amin J; Law MG; Breit SN; Lanza E; Brown , 2012, 'Serum Macrophage Inhibitory Cytokine-1 (MIC-1/GDF15): A Potential Screening Tool for the Prevention of Colon Cancer?', Cancer Epidemiology Biomarkers and Prevention, vol. 21, pp. 337 - 346, http://dx.doi.org/10.1158/1055-9965.EPI-11-0786
    Journal articles | 2012
    Husaini Y; Qiu MR; Lockwood G; Luo X; Shang P; Kuffner T; Tsai VW-W; Lele J; Russell PJ; Brown DA; Breit SN, 2012, 'Macrophage inhibitory cytokine-1 (MIC-1/GDF15) slows cancer development but increases metastases in TRAMP prostate cancer prone mice', PLoS One, vol. 7, pp. e43833, http://dx.doi.org/10.1371/journal.pone.0043833
    Journal articles | 2012
    Macia L; Tsai VWW; Nguyen AD; Johnen H; Kuffner T; Shi Y; Lin S; Herzog H; Brown DA; Breit SN; Sainsbury-Salis A, 2012, 'Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets', PLoS One, vol. 7, pp. e34868, http://dx.doi.org/10.1371/journal.pone.0034868
    Journal articles | 2012
    Tsai VW-W; Husaini Y; Manandhar R; Lee-ng KKM; Hong PZ; Harriott K; Jiang L; Lin S; Sainsbury-Salis A; Brown DA; Breit SN, 2012, 'Anorexia/cachexia of chronic diseases: a role for the TGF-beta family cytokine MIC-1/GDF15', Journal of Cachexia, Sarcopenia and Muscle, vol. 3, pp. 239 - 243, http://dx.doi.org/10.1007/s13539-012-0082-6
    Journal articles | 2011
    Breit SN; Johnen H; Cook AD; Tsai VWW; Mohammad MG; Tamara K; Hong PZ; Marquis C; Lele J; Lockwood G; Lee-Ng M; Husaini Y; Wu L; Hamilton JA; Brown DA, 2011, 'The TGF-β superfamily cytokine, MIC-1/GDF15: A pleotrophic cytokine with roles in inflammation, cancer and metabolism', Growth Factors, vol. 29, pp. 187 - 195, http://dx.doi.org/10.3109/08977194.2011.607137
    Journal articles | 2011
    Brown DA; Tsai VWW; Mohammad MG; Tolhurst O; Breit SN; Sawchenko PE, 2011, 'CCAAT/enhancer binding protein-delta (C/EBPdelta) regulates Th17/Treg balance via an antigen presenting cell - interleukin-10 dependent mechanism in neuroinflammation', MULTIPLE SCLEROSIS JOURNAL, vol. 17, pp. S344 - S344, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209137301142&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2009
    Boyle G; Pedley J; Martyn A; Banducci K; Strutton G; Brown DA; Breit SN; Parsons PG, 2009, 'Macrophage inhibitory cytokine-1 is overexpressed in malignant melanoma and is associated with tumorigenicity', Journal of Investigative Dermatology, vol. 129, pp. 383 - 391, http://dx.doi.org/10.1038/jid.2008.270
    Journal articles | 2009
    Brown DA; Lindmark F; Stattin P; Bälter K; Adami HO; Zheng SL; Xu J; Isaacs WB; Grönberg H; Breit SN; Wiklund FE, 2009, 'Macrophage inhibitory cytokine 1: A new prognostic marker in prostate cancer', Clinical Cancer Research, vol. 15, pp. 6658 - 6664, http://dx.doi.org/10.1158/1078-0432.CCR-08-3126
    Journal articles | 2009
    Horvath L; Zhao L; Lee B; Brown D; Molloy M; Marx G; Boyer M; Breit S; Sutherland R; Henshall S, 2009, 'Identification of candidate biomarkers of therapeutic response to docetaxel in hormone-refractory prostate cancer by proteomic profiling.', J Clin Oncol, vol. 27, pp. 11010, http://www.ncbi.nlm.nih.gov/pubmed/27963974
    Journal articles | 2009
    Shnaper S; Desbaillets I; Brown DA; Murat A; Migliavacca E; Schluep M; Ostermann S; Hamou MF; Stupp R; Breit SN; De Tribolet N; Hegi ME, 2009, 'Elevated levels of MIC-1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worse outcome', International Journal of Cancer, vol. 125, pp. 2624 - 2630, http://dx.doi.org/10.1002/ijc.24639
    Journal articles | 2009
    Wakchoure S; Swain T; Hentunen T; Bauskin AR; Brown DA; Breit SN; Vuopala K; Harris K; Selander K, 2009, 'Expression of macrophage inhibitory cytokine-1 in prostate cancer bone metastases induces osteoclast activation and weight loss', Prostate, vol. 69, pp. 652 - 661, http://dx.doi.org/10.1002/pros.20913
    Journal articles | 2009
    Zhao L; Lee BY; Brown DA; Molloy M; Marx GM; Pavlakis N; Boyer MJ; Stockler M; Kaplan W; Breit SN; Sutherland RL; Henshall SM; Horvath LG, 2009, 'Identification of candidate biomarkers of therapeutic response to docetaxel by proteomic profiling', Cancer research, vol. 69, pp. 7696 - 7703, http://dx.doi.org/10.1158/0008-5472.CAN-08-4901
    Journal articles | 2007
    Brown DA; Moore JJ; Johnen H; Smeets TJ; Bauskin AR; Kuffner T; Weedon H; Milliken ST; Tak PP; Smith MD; Breit SN, 2007, 'Serum macrophage inhibitory cytokine 1 in rheumatoid arthritis - A potential marker of erosive joint destruction', Arthritis Care & Research, vol. 56, pp. 753 - 764, http://dx.doi.org/10.1002/art.22410
    Journal articles | 2007
    Brown DA; Sawchenko PE, 2007, 'Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis', Journal of Comparative Neurology, vol. 502, pp. 236 - 260, http://dx.doi.org/10.1002/cne.21307
    Journal articles | 2007
    Johnen H; Lin S; Kuffner T; Brown DA; Tsai V; Bauskin AR; Wu L; Pankhurst G; Jiang L; Junankar S; Hunter M; Fairlie WD; Lee NJ; Enriquez R; Baldock P; Corey E; Apple F; Murakami M; Lin E; Wang CC; During M; Sainsbury A; Herzog H; Breit SN, 2007, 'Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1', Nature Medicine, vol. 13, pp. 1333 - 1340, http://dx.doi.org/10.1038/nm1677
    Journal articles | 2007
    Selander KS; Brown DA; Sequeiros GB; Hunter M; Desmond R; Parpala T; Risteli J; Breit SN; Jukkola-Vuorinen A, 2007, 'Serum macrophage inhibitory cytokine-1 concentrations correlate with the presence of prostate cancer bone metastases', Cancer Epidemiology Biomarkers and Prevention, vol. 16, pp. 532 - 537, http://dx.doi.org/10.1158/1055-9965.EPI-06-0841
    Journal articles | 2006
    Bauskin AR; Brown DA; Kuffner T; Johnen H; Luo X; Hunter M; Breit SN, 2006, 'Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer', Cancer research, vol. 66, pp. 4983 - 4986, http://dx.doi.org/10.1158/0008-5472.CAN-05-4067
    Journal articles | 2006
    Brown DA; Stephan C; Ward RL; Law MG; Hunter M; Bauskin AR; Amin J; Jung K; Diamandis E; Hampton GM; Russell PJ; Giles GG; Breit SN, 2006, 'Measurement of serum levels of macrophage inhibitory cytokine 1 combined with prostate-specific antigen improves prostate cancer diagnosis', Clinical Cancer Research, vol. 12, pp. 89 - 96, http://dx.doi.org/10.1158/1078-0432.CCR-05-1331
    Journal articles | 2006
    Koopmann J; Rosenzweig C; Zhang ZP; Canto M; Brown DA; Hunter M; Yeo CB; Chan DJ; Breit SN; Goggins M; Hunter M, 2006, 'Serum markers in patients with resectable pancreatic adenocarcinoma: Macrophage inhibitory cytokine 1 versus CA19-9', Clinical Cancer Research, vol. 12, pp. 442 - 446, http://dx.doi.org/10.1158/1078-0432.CCR-05-0564
    Journal articles | 2006
    Rasiah KK; Kench JG; Gardiner-Garden M; Biankin AV; Golovsky D; Brenner PC; Kooner R; O Neill G; Turner J; Delprado W; Lee CS; Brown DA; Breit SN; Grygiel JJ; Horvath LG; Stricker PD; Sutherland RL; Henshall SM, 2006, 'Aberrant neuropepticle Y and macrophage inhibitory cytokine-1 expression are early events in prostate cancer development and are associated with poor prognosis', Cancer epidemiology biomarkers and prevention, vol. 15, pp. 711 - 716, http://dx.doi.org/10.1158/1055-9965.EPI-05-0752
    Journal articles | 2006
    Stephan C; Xu C; Brown DA; Breit SN; Michael AW; Nakamura T; Diamandis E; Meyer H; Cammann H; Jung K, 2006, 'Three new serum markers for prostate cancer detection within a percent free PSA-based artificial neural network', Prostate, vol. 66, pp. 651 - 659, http://dx.doi.org/10.1002/pros.20381
    Journal articles | 2006
    Xu J; Kimball T; Lorenz J; Brown DA; Bauskin AR; Klevitsky R; Hewett T; Breit SN; Molkentin J, 2006, 'GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation', Circulation Research, vol. 98, pp. 342 - 350, http://dx.doi.org/10.1161/01.RES.0000202804.84885.d0
    Journal articles | 2005
    Liu T, 2005, 'The propeptide mediates formation of stromal stores of ProMIC-1: role in determining prostate cancer outcome', Cancer Research, vol. 65, pp. 2330 - 2336, http://dx.doi.org/10.1158/0008-5472.CAN-04-3827
    Journal articles | 2005
    Weber F; Byrne S; Le S; Brown DA; Breit SN; Scolyer R; Halliday GM, 2005, 'Transforming growth factor-beta(1) immobilises dendritic cells within skin tumours and facilitates tumour escape from the immune system', Cancer Immunology and Immunotherapy, vol. 54, pp. 898 - 906, http://dx.doi.org/10.1007/s00262-004-0652-3
    Journal articles | 2004
    Koopmann J; Buckhaults P; Brown DA; Zahurak M; Sato N; Fukushima N; Sokoll L; Chan DW; Yeo C; Hruban R; Breit SN; Kinzler KW; Vogelstein B; Goggins M, 2004, 'Serum macrophage inhibitory cytokine 1 as a marker of pancreatic andother periampullary cancers', Clinical Cancer Research, vol. 10, pp. 2386 - 2392, http://dx.doi.org/10.1158/1078-0432.CCR-03-0165
    Journal articles | 2004
    Tong S; Marjono B; Brown DA; Mulvey S; Breit SN; Manuelpillai U; Wallace EM, 2004, 'Serum concentrations of macrophage inhibitory cytokine 1 (MIC 1) as apredictor of miscarriage', Lancet, vol. 363, pp. 129 - 130, http://dx.doi.org/10.1016/S0140-6736(03)15265-8
    Journal articles | 2004
    Wallace EM; Marjono B; Brown DA; Crossley J; Aitken DK; Tong S; Breit SN, 2004, 'Maternal serum and amniotic fluid levels of macrophage inhibitorycytokine 1 in Down syndrome and chromosomally normal pregnancies', Prenatal Diagnosis, vol. 24, pp. 224 - 226, http://dx.doi.org/10.1002/pd.791
    Journal articles | 2003
    Brown DA; Ward RL; Buckhaults P; Liu T; Romans KE; Hawkins NJ; Bauskin AR; Kinzler KW; Vogelstein B; Breit SN, 2003, 'MIC 1 serum level and genotype: Associations with progress and prognosis of colorectal carcinoma', Clinical Cancer Research, vol. 9, pp. 2642 - 2650
    Journal articles | 2003
    Delzell E; Brown DA; Matthews R, 2003, 'Mortality among hourly motor vehicle manufacturing workers', Journal of Occupational and Environmental Medicine, vol. 45, pp. 813 - 830, http://dx.doi.org/10.1097/01.jom.0000079092.95532.49
    Journal articles | 2003
    Keelan JA; Wang K; Chaiworapongsa T; Romero R; Mitchell MD; Sato TA; Brown DA; Fairlie WD; Breit SN, 2003, 'Macrophase hihibitory cytokine 1 (MIC-1) in fetal membranes and amniotic fluid from pregnancies with and without preterm labour and premature rupture of membranes', Molecular Human Reproduction, vol. 9, pp. 535 - 540, http://dx.doi.org/10.1093/molehr/gag068
    Journal articles | 2003
    Liu T, 2003, 'Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum', Proceedings of the National Academy of Sciences of the United States of America, vol. 100, pp. 3410 - 3415, http://dx.doi.org/10.1073/pnas.0530278100
    Journal articles | 2003
    Liu T; Bauskin AR; Zaunders J; Brown DA; Pankhurst S; Russell PJ; Breit SN, 2003, 'Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells', Cancer research, vol. 63, pp. 5034 - 5040
    Journal articles | 2003
    Marjono AB; Brown DA; Horton KE; Wallace EM; Breit SN; Manuelpillai U, 2003, 'Macrophage Inhibitory Cytokine-1 in Gestational Tissues and Maternal Serum in Normal and Pre-eclamptic Pregnancy', Placenta, vol. 24, pp. 100 - 106, http://dx.doi.org/10.1053/plac.2002.0881
    Journal articles | 2003
    Yang H; Filipovic Z; Brown DA; Breit SN; Vassilev LT, 2003, 'Macrophage inhibitory cytokine-1: a novel biomarker for p53 pathway activation', Molecular Cancer Therapeutics, vol. 2, pp. 1023 - 1029
    Journal articles | 2002
    Liu T, 2002, 'Antibody-based approach to high-volume genotyping for MIC-1 polymorphism', BioTechniques, vol. 33, pp. 118 - 120
    Journal articles | 2002
    Liu T, 2002, 'Concentration in plasma of macrophage inhibitory cytokine-1 and risk of cardiovascular events in women: a nested case-control study', Lancet, vol. 359, pp. 2159 - 2163, http://dx.doi.org/10.1016/S0140-6736(02)09093-1
    Journal articles | 2002
    Talley LI; Grizzle WE; Waterbor JW; Brown D; Weiss H; Frost AR, 2002, 'Hormone receptors and proliferation in breast carcinomas of equivalent histologic grades in pre- and postmenopausal women', International Journal of Cancer, vol. 98, pp. 118 - 127, http://dx.doi.org/10.1002/ijc.10171
    Journal articles | 2000
    Bauskin AR; Zhang H; Fairlie WD; He XY; Russell PJ; Moore A; Brown DM; Stanley K; Breit SN, 2000, 'The Propeptide of macrophage inhibitory cytokine (MIC-1) , a TGF-b superfamily member, act as a quality control determinant for correctly folded MIC-1.', European Molecular Biology Organization, vol. 19, pp. 2212 - 2220, http://dx.doi.org/10.1093/emboj/19.10.2212
    Journal articles | 2000
    Brown DA; Delzell E, 2000, 'Motor vehicle manufacturing and prostate cancer', American Journal of Industrial Medicine, vol. 38, pp. 59 - 70, http://dx.doi.org/10.1002/1097-0274(200007)38:1<59::AID-AJIM7>3.0.CO;2-Y
    Journal articles | 2000
    Moore AG; Brown DA; Fairlie WD; Bauskin AR; Brown PK; Munier MLC; Russell PK; Salamonsen LA; Wallace EM; Breit SN, 2000, 'The transforming growth factor-β superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women', Journal of Clinical Endocrinology and Metabolism, vol. 85, pp. 4781 - 4788, http://dx.doi.org/10.1210/jc.85.12.4781
    Journal articles | 1997
    Brown DA; Breit SN, 1997, 'Scleroderma Lung Disease', Biodrugs, vol. 8, pp. 185 - 192, http://dx.doi.org/10.2165/00063030-199708030-00004
    Journal articles | 1997
    Carr AD; Brown DM; Cooper DA, 1997, 'Portal vein thrombosis in patients receiving indinavir, an HIV protease inhibitor', AIDS, vol. 11, pp. 1657 - 1658
    Journal articles | 1997
    Manne U; Myers RB; Moron C; Poczatek RB; Dillard S; Weiss H; Brown D; Srivastava S; Grizzle WE, 1997, 'Prognostic significance of Bcl-2 expression and p53 nuclear accumulation in colorectal adenocarcinoma', International Journal of Cancer, vol. 74, pp. 346 - 358, http://dx.doi.org/10.1002/(SICI)1097-0215(19970620)74:3<346::AID-IJC19>3.0.CO;2-9
    Journal articles | 1996
    Dean Roye G; Myers RB; Brown D; Poczatek R; Beenken SW; Grizzle WE, 1996, 'CD44 expression in dysplastic epithelium and squamous-cell carcinoma of the esophagus', International Journal of Cancer, vol. 69, pp. 254 - 258, http://dx.doi.org/10.1002/(SICI)1097-0215(19960822)69:4<254::AID-IJC2>3.0.CO;2-W
    Journal articles | 1996
    Myers RB; Brown D; Oelschlager DK; Waterbor JW; Ernest Marshall M; Srivastava S; Stockard CR; Urban DA; Grizzle WE, 1996, 'Elevated serum levels of p105(erbB-2) in patients with advanced-stage prostatic adenocarcinoma', International Journal of Cancer, vol. 69, pp. 398 - 402, http://dx.doi.org/10.1002/(SICI)1097-0215(19961021)69:5<398::AID-IJC8>3.0.CO;2-0
    Journal articles | 1996
    Myers RB; Srivastava S; Oelschlager DK; Brown D; Grizzle WE, 1996, 'Expression of nm23-H1 in prostatic intraepithelial neoplasia and adenocarcinoma', Human Pathology, vol. 27, pp. 1021 - 1024, http://dx.doi.org/10.1016/S0046-8177(96)90278-6
  • Conference Abstracts | 2019
    Mahon KL; Lin H-M; Lee-Ng M; Stockler MR; Gurney H; Mallesara G; Briscoe KP; Marx GM; Higano CS; De Bono JS; Chi KN; Brown D; Breit SN; Horvath L, 2019, 'Clinical validation of circulating cytokines as markers of prognosis and response to docetaxel in men with metastatic castration-resistant prostate cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, CA, San Francisco, Vol. 37, presented at ASCO-SITC Clinical Immuno-Oncology Symposium, CA, San Francisco, 28 February 2019 - 02 March 2019, http://dx.doi.org/10.1200/JCO.2019.37.7_suppl.230
    Conference Abstracts | 2019
    Mahon KL; Lin HM; Lee-Ng M; Cain D; Jacobs C; Stockler MR; Gurney H; Mallesara G; Briscoe K; Marx G; Higano CS; de Bono JS; Chi KN; Breit SN; Brown DA; Horvath LG, 2019, 'Company Profiles', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, Vol. 15, pp. 33 - 33, http://dx.doi.org/10.1111/ajco.13198
    Preprints | 2018
    Afrasiabi A; Parnell GP; Fewings N; Schibeci SD; Basuki MA; Chandramohan R; Brown DA; Swaminathan S; McKay FC; Stewart GJ; Booth DR, 2018, Genetic evidence that the latency III stage of Epstein-Barr Virus infection is a therapeutic target for Multiple Sclerosis, http://dx.doi.org/10.1101/390609
    Conference Abstracts | 2016
    Golakani HM; Mohammad M; Li H; Saxena M; Breit S; Ruitenberg M; Brown D, 2016, 'Dynamics of inflammatory immune response in a mouse model of traumatic spinal cord injury, potential therapeutic targets', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 566 - 566, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610401330&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Mahon K; Lin H-M; Spielman C; Lee-Ng M; Gurney H; Mallesara G; Stockler M; Briscoe K; Marx G; Breit SN; Brown D; Horvath L, 2016, 'PHASE II TRIAL OF CIRCULATING CYTOKINES AS MARKERS OF DOCETAXEL RESISTANCE IN METASTATIC CASTRATE-RESISTANT PROSTATE CANCER (mCRPC)', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, Vol. 12, pp. 37 - 37, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000380004900039&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Mohammad MG; Tsai V; Li H; Hassanpour M; Hart P; Breit S; Sawchenko P; Brown D, 2016, 'A choroid-forebrain-lymphatic pathway for the maintenance of CNS immune tolerance', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 166 - 166, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400332&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Barber D; Zhang HP; Lee-Ng M; Breit SN; Brown DA; Danta M, 2015, 'MIC1/GDF15 as a novel biomarker of colonic neoplasia', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, Vol. 30, pp. 76 - 77, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000364505900153&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Abstracts | 2015
    Sasson SC; McGill K; Weinholt L; Carr A; Brown DA; Kelleher AD; Breit SN; Sewell WA, 2015, 'COMPARISON OF THE FREELITE (TM) SERUM FREE LIGHT CHAIN (SFLC) ASSAY WITH SERUM AND URINE ELECTROPHORESIS/IMMUNOFIXATION AND THE N LATEX FLC ASSAY', in INTERNAL MEDICINE JOURNAL, WILEY-BLACKWELL, Vol. 45, pp. 24 - 24, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360834700077&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Watson B; Baxter A; Flood V; Schofield L; Zhang HP; Lee-Ng M; How-Chow D; Breit SN; Brown DA; Danta M, 2015, 'MACROPHAGE INHIBITORY CYTOKINE-1 (MIC-1) IS ASSOCIATED WITH DEGREE OF LIVER FIBROSIS IN HCV-RELATED LIVER DISEASE - THE MILC STUDY', in JOURNAL OF HEPATOLOGY, ELSEVIER SCIENCE BV, AUSTRIA, Vienna, Vol. 62, pp. S337 - S337, presented at 50th International Liver Congress of the European-Association-for-the-Study-of-the-Liver, AUSTRIA, Vienna, 22 April 2015 - 26 April 2015, http://dx.doi.org/10.1016/S0168-8278(15)30319-6
    Conference Abstracts | 2015
    Watson B; Baxter A; Flood V; Schofield L; Zhang HP; Lee-Ng M; How-Chow D; Briet S; Brown D; Danta M, 2015, 'Macrophage inhibitory cytokine-1 (MIC-1) is associated with degree of liver fibrosis in HCV-related liver disease - the milc study', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, Vol. 30, pp. 99 - 100, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000364505900196&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2014
    Jiang J; Sachdev PS; Brown DA; Breit S; Crawford J; Smith E; Liu T; Trollor J; Wen W, 2014, 'Macrophage Inhibitory Cytokine-1 Is Linked to Brain Volume in Older Individuals [Poster Abstract 3194]', in Proceedings of the 20th Annual Meeting of the Organization for Human Brain Mapping (OHBM), 20th Annual Meeting of the Organization for Human Brain Mapping (OHBM), Hamburg, Germany, presented at 20th Annual Meeting of the Organization for Human Brain Mapping (OHBM), Hamburg, Germany, 08 June 2014 - 12 June 2014
    Conference Papers | 2014
    Mohammad M; Tsai VWW; Ruitenberg M; Hassanpour M; Li H; Hart P; Breit S; Sawchenko P; Brown D, 2014, 'CNS DCs modulate peripheral anti-CNS immunity', in JOURNAL OF NEUROIMMUNOLOGY, ELSEVIER SCIENCE BV, GERMANY, Mainz, pp. 82 - 82, presented at 12th International Congress of Neuroimmunology (ISNI), GERMANY, Mainz, 09 November 2014 - 13 November 2014, http://dx.doi.org/10.1016/j.jneuroim.2014.08.218
    Conference Papers | 2013
    Horvath L; Chatfield MD; Lee-Ng M; Lin H-M; Castillo L; Breit SN; Brown DA; Molloy MP; Marx GM; Pavlakis N; Boyer MJ; Stockier MR; Wykes R; Henshall SM; Mahon KL, 2013, 'The role of macrophages in docetaxel (DTX) resistance in castrate-resistant prostate cancer (CRPC).', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, presented at 49th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2013 - 04 June 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000335419605294&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Husaini Y; Qiu MR; Lockwood G; Jiang L; Tsai VWW; Russell PJ; Brown DA; Breit SN, 2013, 'Expression of the TGF-b superfamily cytokine MIC-1/GDF15slows tumor growth but increases metastases in prostate cancer prone TRAMP mice', in BJU INTERNATIONAL, WILEY-BLACKWELL, pp. 36 - 36, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000321969100093&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Mahon K; Chatfield M; Breit S; Brown D; Molloy M; Marx G; Pavlakis N; Boyer M; Stockler M; Horvath L, 2013, 'The role of macrophages in Docetaxel (DTX) resistance in castrate resistant prostate cancer (CRPC)', in BJU INTERNATIONAL, WILEY-BLACKWELL, pp. 30 - 31, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000321969100078&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2012
    Mohammad MG; Tsai VWW; Hassanpour M; Li H; Breit SN; Hart PH; Sawchenko PE; Brown DA, 2012, 'A Forebrain Immune Cellular Pathway for the Prevention of CNS Autoimmunity', in JOURNAL OF NEUROIMMUNOLOGY, ELSEVIER SCIENCE BV, Boston, MA, pp. 124 - 124, presented at 11th International Congress of Neuroimmunology (ISNI), Boston, MA, 04 November 2012 - 08 November 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000312764800334&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2011
    Breit SN; Husaini Y; Lockwood G; Kuffner T; Tsai V; Luo XW; Jiang L; Lee-Ng M; Zhang HP; Wu L; Brown DA, 2011, 'The role of the TGF-beta superfamily cytokine MIC-1/GDF15 in biology and medicine', in CYTOKINE, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, ITALY, Florence, pp. 40 - 40, presented at 9th Joint Meeting of the International-Cytokine-Society/International-Society-for-Interferon-and-Cytokine-Research, ITALY, Florence, 09 October 2011 - 12 October 2011, http://dx.doi.org/10.1016/j.cyto.2011.07.122
    Conference Papers | 2011
    Mohammad MG; Tsai VWW; Tolhurst O; Breit SN; Sawchenko PE; Brown DA, 2011, 'Dendritic cell CCAAT/enhancer binding protein delta modulates Th17/Treg responses in an IL-10 dependent manner', in MULTIPLE SCLEROSIS JOURNAL, SAGE PUBLICATIONS LTD, AUSTRALIA, Melbourne, pp. 698 - 699, presented at Progress in Multiple Sclerosis Research Conference, AUSTRALIA, Melbourne, 26 October 2011 - 28 October 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000303319000140&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2010
    Puls RL; Brown D; Fahey P; Amin J; Breit S; Carr A, 2010, 'Macrophage inhibitory cytokine 1 (MIC-1) serum levels in the Lipodystrophy Case Definition Study', in ANTIVIRAL THERAPY, INT MEDICAL PRESS LTD, ENGLAND, London, pp. A28 - A29, presented at 12th International Workshop on Adverse Drug Reactions and Co-Morbidities in HIV, ENGLAND, London, 04 November 2010 - 06 November 2010, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000287431200046&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2010
    Puls RL; Brown D; Fahey P; Amin J; Breit S; Carr A, 2010, 'Macrophage inhibitory cytokine 1 (MIC-1) serum levels in the Lipodystrophy Case Definition Study', in ANTIVIRAL THERAPY, INT MEDICAL PRESS LTD, ENGLAND, London, pp. A28 - A29, presented at 12th International Workshop on Adverse Drug Reactions and Co-Morbidities in HIV, ENGLAND, London, 04 November 2010 - 06 November 2010, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000287431500032&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2008
    Breit SN; Johnen H; Lin S; Kuffner T; Brown DA; Tsai V; Bauskin AR; Corey L; Sainsbury A; Herzog H, 2008, 'The TGF-beta superfamily cytokine MIC-1 causes tumour-induced anorexia/cachexia by modulating appetite control centres in the hypothalamus', in Cytokine, Academic Press Ltd Elsevier Science Ltd, London, England, pp. 323 - 323, presented at Cytokine, Montreal, CANADA, - , http://dx.doi.org/10.1016/j.cyto.2008.07.421
    Conference Papers | 2007
    Jiang L; Brown DA; Johnen H; Qiu MR; Curmi PM; Kuffner T; Brown L; Mazzanti M; Breit SN, 2007, 'Role of chloride intracellular channel protein-1 (CLIC1) in cell-mediated immunity', in Inflammation Research, Birkhauser Verlag Ag, pp. S406 - S406, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000247517900156&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2001
    Brown DA; Liu T; Ward RL; Hawkins NJ; Fairlie WD; Bauskin AR; Russell PJ; Quinn DI; Grygiel JJ; Moore AG; Sutherland RL; Turner J; Kingsley EA; Breit SN, 2001, 'Macrophage inhibitory cytokine-1 (MIC-1) in epithelial neoplasia', in JOURNAL OF LEUKOCYTE BIOLOGY, FEDERATION AMER SOC EXP BIOL, pp. 90 - 90, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000171482200311&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1