Dr Dulama   Richani
Postdoctoral Fellow

Dr Dulama Richani

2014   PhD in Medicine, University of Adelaide, Australia

2007   Bachelor of Biotechnology (Honours, 1st Class), Flinders University, Australia

Medicine & Health
Discip Obstetrics&Gynaecology

Dr Dulama Richani is a Postdoctoral Research Fellow at the School of Women’s and Children’s Health, and Fertility & Research Centre, at UNSW. 

 

Dulama is an emerging research leader in the areas of oocyte maturation and assisted reproductive technologies. Through basic research, she has made advances in our fundamental understanding of the endocrine and local factors which regulate oocyte quality and is using these new insights to develop modern approaches to fertility treatments for women (with a particular focus on the reproductive technology IVM).

 

KEY ACHEVEMENTS:

  • Publications: She has published over 20 peer reviewed publications in the last 6 years; 88% of them are in top quartile of journals. The impact of her research is reflected by her excellent FWCI of 2.89 (SciVal, 2019), meaning that her research receives almost triple the expected citations across all disciplines in which she publishes.
  • Scientific Presentations: She has delivered 10 oral presentations at major national and international conferences and 4 invited institute talks. Additionally, she has been the presenting author of 15 conference presentations.
  • Funding: Attained $210,612 in funding (Project, industry & equipment grants with 75% as CIA, 2 scholarships, & 12 travel awards).
  • Academic Excellence: Awarded Dean’s Commendation for Doctoral Thesis of Excellence (2014); Awarded the School Best Publication Award (UNSW, 2019).
  • Contributions to Scientific Community: Elected Early Career Research Representative for the Australian Society for Reproductive Biology (SRB); Member of 3 university committees, peer-reviewer for several multi-disciplinary scientific journals, Conference Convener & Chair of the 2018 NSW Reproduction Forum (Australia).
  • Research Leadership: She has been primary supervisor to 4 Honours students, and supervisor to 3 visiting international postdoctoral fellows.
Phone
02 9385 3631

Publications

  • Journal articles | 2021
    Dr Dulama Richani
    Richani D; Dunning KR; Thompson JG; Gilchrist RB, 2021, 'Metabolic co-dependence of the oocyte and cumulus cells: Essential role in determining oocyte developmental competence', Human Reproduction Update, vol. 27, pp. 27 - 47, http://dx.doi.org/10.1093/humupd/dmaa043
    Journal articles | 2020
    Dr Dulama Richani
    Bertoldo MJ; Listijono DR; Ho WHJ; Riepsamen AH; Goss DM; Richani D; Jin XL; Mahbub S; Campbell JM; Habibalahi A; Loh WGN; Youngson NA; Maniam J; Wong ASA; Selesniemi K; Bustamante S; Li C; Zhao Y; Marinova MB; Kim LJ; Lau L; Wu RM; Mikolaizak AS; Araki T; Le Couteur DG; Turner N; Morris MJ; Walters KA; Goldys E; O'Neill C; Gilchrist RB; Sinclair DA; Homer HA; Wu LE, 2020, 'NAD+ Repletion Rescues Female Fertility during Reproductive Aging', Cell Reports, vol. 30, pp. 1670 - 1681.e7, http://dx.doi.org/10.1016/j.celrep.2020.01.058
    Journal articles | 2020
    Dr Dulama Richani
    Winship A; Donoghue J; Houston BJ; Martin JH; Lord T; Adwal A; Gonzalez M; Desroziers E; Ahmad G; Richani D; Bromfield EG, 2020, 'Reproductive health research in Australia and New Zealand: Highlights from the Annual Meeting of the Society for Reproductive Biology, 2019', Reproduction, Fertility and Development, vol. 32, pp. 637 - 647, http://dx.doi.org/10.1071/RD19449
    Journal articles | 2020
    Dr Dulama Richani
    Zhao Y; Liao X; Krysta AE; Bertoldo MJ; Richani D; Gilchrist RB, 2020, 'Capacitation IVM improves cumulus function and oocyte quality in minimally stimulated mice', Journal of Assisted Reproduction and Genetics, vol. 37, pp. 77 - 88, http://dx.doi.org/10.1007/s10815-019-01610-x
    Journal articles | 2020
    Dr Dulama Richani
    Stocker WA; Walton KL; Richani D; Chan KL; Beilby KH; Finger BJ; Green MP; Gilchrist RB; Harrison CA, 2020, 'A variant of human growth differentiation factor-9 that improves oocyte developmental competence', Journal of Biological Chemistry, vol. 295, pp. 7981 - 7991, http://dx.doi.org/10.1074/JBC.RA120.013050
    Journal articles | 2019
    Dr Dulama Richani
    Richani D; Constance K; Lien S; Agapiou D; Stocker WA; Hedger MP; Ledger WL; Thompson JG; Robertson DM; Mottershead DG; Walton KL; Harrison CA; Gilchrist RB, 2019, 'Cumulin and FSH cooperate to regulate inhibin B and activin B production by human granulosa-lutein cells in vitro', Endocrinology, vol. 160, pp. 853 - 862, http://dx.doi.org/10.1210/en.2018-01026
    Journal articles | 2019
    Dr Dulama Richani
    Bertoldo MJ; Cheung MY; Sia ZK; Agapiou D; Corley SM; Wilkins MR; Richani D; Harrison CA; Gilchrist RB, 2019, 'Non-canonical cyclic AMP SMAD1/5/8 signalling in human granulosa cells', Molecular and Cellular Endocrinology, vol. 490, pp. 37 - 46, http://dx.doi.org/10.1016/j.mce.2019.04.003
    Journal articles | 2019
    Dr Dulama Richani
    Richani D; Lavea CF; Kanakkaparambil R; Riepsamen AH; Bertoldo MJ; Bustamante S; Gilchrist RB, 2019, 'Participation of the adenosine salvage pathway and cyclic AMP modulation in oocyte energy metabolism', Scientific Reports, vol. 9, pp. 18395, http://dx.doi.org/10.1038/s41598-019-54693-y
    Journal articles | 2019
    Dr Dulama Richani
    Bromfield EG; Dowland SN; Dunleavy JEM; Dunning KR; Holland OJ; Houston BJ; Pankhurst MW; Richani D; Riepsamen AH; Rose R; Bertoldo MJ, 2019, 'Fifty years of reproductive biology in Australia: Highlights from the 50th Annual Meeting of the Society for Reproductive Biology (SRB)', Reproduction, Fertility and Development, vol. 31, pp. 829 - 836, http://dx.doi.org/10.1071/RD18436
    Journal articles | 2018
    Dr Dulama Richani
    Bustamante S; Jayasena T; Richani D; Gilchrist RB; Wu LE; Sinclair DA; Sachdev PS; Braidy N, 2018, 'Quantifying the cellular NAD+ metabolome using a tandem liquid chromatography mass spectrometry approach', Metabolomics, vol. 14, http://dx.doi.org/10.1007/s11306-017-1310-z
    Journal articles | 2018
    Dr Dulama Richani
    Richani D; Gilchrist RB, 2018, 'The epidermal growth factor network: Role in oocyte growth, maturation and developmental competence', Human Reproduction Update, vol. 24, pp. 1 - 14, http://dx.doi.org/10.1093/humupd/dmx029
    Journal articles | 2017
    Dr Dulama Richani
    Chowdhury MKH; Turner N; Bentley NL; Das A; Wu LE; Richani D; Bustamante S; Gilchrist RB; Morris MJ; Shepherd PR; Smith GC, 2017, 'Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/srep40159
    Journal articles | 2017
    Dr Dulama Richani
    Patino LC; Walton KL; Mueller TD; Johnson KE; Stocker W; Richani D; Agapiou D; Gilchrist RB; Laissue P; Harrison CA, 2017, 'BMP15 mutations associated with primary ovarian insufficiency reduce expression, activity, or synergy with gdf9', Journal of Clinical Endocrinology and Metabolism, vol. 102, pp. 1009 - 1019, http://dx.doi.org/10.1210/jc.2016-3503
    Journal articles | 2017
    Dr Dulama Richani
    Bustamante S; Gilchrist RB; Richani D, 2017, 'A sensitive method for the separation and quantification of low-level adenine nucleotides using porous graphitic carbon-based liquid chromatography and tandem mass spectrometry', Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, vol. 1061-1062, pp. 445 - 451, http://dx.doi.org/10.1016/j.jchromb.2017.07.044
    Journal articles | 2016
    Dr Dulama Richani
    Gilchrist RB; Luciano AM; Richani D; Zeng HT; Wang X; De Vos M; Sugimura S; Smitz J; Richard FJ; Thompson JG, 2016, 'Oocyte maturation and quality: Role of cyclic nucleotides', Reproduction, vol. 152, pp. R143 - R157, http://dx.doi.org/10.1530/REP-15-0606
    Journal articles | 2015
    Dr Dulama Richani
    Gilchrist RB; Zeng HT; Wang X; Richani D; Smitz J; Thompson JG, 2015, 'Reevaluation and evolution of the simulated physiological oocyte maturation system', Theriogenology, vol. 84, pp. 656 - 657, http://dx.doi.org/10.1016/j.theriogenology.2015.03.032
    Journal articles | 2015
    Dr Dulama Richani
    Gilchrist RB; Zeng HT; Wang X; Richani D; Smitz J; Thompson JG, 2015, 'Reevaluation and evolution of the simulated physiological oocyte maturation system', Theriogenology, http://dx.doi.org/10.1016/j.theriogenology.2015.03.032
    Journal articles | 2015
    Dr Dulama Richani
    Brown HM; Anastasi MR; Frank LA; Kind KL; Richani D; Robker RL; Russell DL; Gilchrist RB; Thompson JG, 2015, 'Hemoglobin: A gas transport molecule that is hormonally regulated in the ovarian follicle in mice and humans', Biology of Reproduction, vol. 92, http://dx.doi.org/10.1095/biolreprod.114.124594
    Journal articles | 2015
    Dr Dulama Richani
    Mottershead DG; Sugimura S; Al-Musawi SL; Li JJ; Richani D; White MA; Martin GA; Trotta AP; Ritter LJ; Shi J; Mueller TD; Harrison CA; Gilchrist RB, 2015, 'Cumulin, an oocyte-secreted heterodimer of the transforming growth factor-β family, is a potent activator of granulosa cells and improves oocyte quality', Journal of Biological Chemistry, vol. 290, pp. 24007 - 24020, http://dx.doi.org/10.1074/jbc.M115.671487
    Journal articles | 2014
    Dr Dulama Richani
    Zeng HT; Richani D; Sutton-McDowall ML; Ren Z; Smitz JEJ; Stokes Y; Gilchrist RB; Thompson JG, 2014, 'Prematuration with cyclic adenosine monophosphate modulators alters cumulus cell and oocyte metabolism and enhances developmental competence of in vitro- matured mouse oocytes', Biology of Reproduction, vol. 91, http://dx.doi.org/10.1095/biolreprod.114.118471
    Journal articles | 2014
    Dr Dulama Richani
    Richani D; Sutton-McDowall ML; Frank LA; Gilchrist RB; Thompson JG, 2014, 'Effect of epidermal growth factor-like peptides on the metabolism of in vitro-matured mouse oocytes and cumulus cells', Biology of Reproduction, vol. 90, http://dx.doi.org/10.1095/biolreprod.113.115311
    Journal articles | 2014
    Dr Dulama Richani
    Richani D; Wang X; Zeng HT; Smitz J; Thompson JG; Gilchrist RB, 2014, 'Pre-maturation with cAMP modulators in conjunction with EGF-like peptides during in vitro maturation enhances mouse oocyte developmental competence', Molecular Reproduction and Development, vol. 81, pp. 422 - 435, http://dx.doi.org/10.1002/mrd.22307
    Journal articles | 2013
    Dr Dulama Richani
    Gilchrist RB; Richani D, 2013, 'Somatic guidance for the oocyte', Developmental Cell, vol. 27, pp. 603 - 605, http://dx.doi.org/10.1016/j.devcel.2013.12.006
    Journal articles | 2013
    Dr Dulama Richani
    Richani D; Ritter LJ; Thompson JG; Gilchrist RB, 2013, 'Mode of oocyte maturation affects EGF-like peptide function and oocyte competence', Molecular Human Reproduction, vol. 19, pp. 500 - 509, http://dx.doi.org/10.1093/molehr/gat028
    Journal articles | 2012
    Dr Dulama Richani
    Richani D; Ritter LJ; Thompson JG; Gilchrist RB, 2012, 'Consequences of In Vitro Maturation of Oocytes on Cumulus Cell EGF-Like Peptide Signaling.', Biology of Reproduction, vol. 87, pp. 365 - 365, http://dx.doi.org/10.1093/biolreprod/87.s1.365
  • Conference Abstracts | 2019
    Dr Dulama Richani
    Richani D; Constance K; Lien S; Agapiou D; Stocker W; Hedger M; Ledger W; Thompson J; Robertson D; Mottershead D; Walton K; Harrison C; Gilchrist R, 2019, 'Cumulin and FSH cooperate to regulate inhibin B and activin B production by human granulosa-lutein cells in vitro', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Vienna, AUSTRIA, Vol. 34, pp. 408 - 408, presented at 35th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), Vienna, AUSTRIA, 24 June 2019 - 26 June 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000484057200856&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2018
    Dr Dulama Richani
    Gilchrist R; Richani D; Sugimura S, 2018, 'Follicular guidance for oocyte developmental competence', in Proceedings of the 10th International Ruminant Reproduction Symposium (IRRS 2018), BRAZILIAN COLL ANIMAL REPRODUCTION, Foz do Iguacu, Brazil, pp. 721 - 726, presented at 10th International Ruminant Reproduction Symposium (IRRS 2018);, Foz do Iguacu, Brazil, 26 September 2018 - 20 September 2018, http://dx.doi.org/10.21451/1984-3143-AR2018-0035

Awards

COMPETITIONS/AWARDS:

2019    Awarded School Best Publication Award, School of Women’s and Children’s Health, UNSW Sydney.

2015    Selected finalist in the Hudson Institute of Medical Research (MIMR-PHI) 'Award for Excellence' for best ECR poster at the 2015 SRB Annual Meeting, Adelaide, Australia.

2015    Selected finalist in the annual Tow Research Awards for ECR poster prize.

2015    Selected finalist in the David Healy New Investigator Award, 44th Annual Meeting of the Society for Reproductive Biology, Sydney, Australia.

  1. Selected finalist in the Adelaide Research & Innovation Pty Ltd Award, Faculty of Health Sciences Postgraduate Research Conference, University of Adelaide.

 

Grants

2019 NHMRC Centre for Research Excellence project support grant

 

Media