Conjoint Professor

Professor Jonathan Sprent

medicine-health
St Vincent's Clinical School

Publications

  • Books | 2002
    Professor Jonathan Sprent
    Sprent J; Surh CD, 2002, T cell memory, http://dx.doi.org/10.1146/annurev.immunol.20.100101.151926
    Book Chapters | 2001
    Professor Jonathan Sprent
    Sun S; Zhang X; Tough D; Sprent J, 2001, 'Multiple effects of immunostimulatory DNA on T cells and the role of type I interferons', in Immunostimulatory DNA Sequences, Springer Berlin Heidelberg, pp. 77 - 84, http://dx.doi.org/10.1007/978-3-642-56866-4_8
    Books | 1999
    Professor Jonathan Sprent
    Sun S; Sprent J, 1999, Role of type I interferons in T cell activation induced by CpG DNA
    Book Chapters | 1998
    Professor Jonathan Sprent
    Sprent J; Surh CD, 1998, 'Thymus', in Encyclopedia of Immunology, Elsevier, pp. 2304 - 2309, http://dx.doi.org/10.1006/rwei.1999.0581
    Book Chapters | 1998
    Professor Jonathan Sprent
    Sprent J, 1998, 'Mixed Lymphocyte Reaction', in Encyclopedia of Immunology, Elsevier, pp. 1733 - 1736, http://dx.doi.org/10.1006/rwei.1999.0439
    Books | 1996
    Professor Jonathan Sprent
    Sprent J; Kishimoto H; Cai Z; Surh CD; Brunmark A; Jackson MR; Peterson PA, 1996, The thymus and T cell death, http://dx.doi.org/10.1007/978-1-4899-0274-0_20
    Book Chapters | 1994
    Professor Jonathan Sprent
    Sprent J; Kosaka H; Surh CD, 1994, 'Tolerogenicity of Thymic Epithelial Cells: Studies with Allogeneic and Xenogeneic Chimeras', in Rejection and Tolerance, Springer Netherlands, pp. 125 - 140, http://dx.doi.org/10.1007/978-94-011-0802-7_12
    Book Chapters | 1990
    Professor Jonathan Sprent
    Lawrance SK; Karlsson L; Price J; Quaranta V; Ron Y; Sprent J; Peterson PA, 1990, 'T Cell Recognition of Major Histocompatibility Complex Antigens in HLA Class II Transgenic Mice', in Transgenic Mice and Mutants in MHC Research, Springer Berlin Heidelberg, pp. 247 - 256, http://dx.doi.org/10.1007/978-3-642-75442-5_33
    Book Chapters | 1985
    Professor Jonathan Sprent
    Sprent J, 1985, 'Migratory Properties and Radiosensitivity of Lymphocytes', in Radiolabeled Cellular Blood Elements, Springer US, pp. 31 - 50, http://dx.doi.org/10.1007/978-1-4684-4922-8_3
    Book Chapters | 1982
    Professor Jonathan Sprent
    Webb SR; Bruce J; Molnar-Kimber K; Wilson DB; Sprent J, 1982, 'Anti-H-2 Reactivity of Mls-Specific T Cell Clones', in Isolation Characterization, and Utilization of T Lymphocyte Clones, Elsevier, pp. 331 - 339, http://dx.doi.org/10.1016/b978-0-12-249920-3.50032-6
    Book Chapters | 1980
    Professor Jonathan Sprent
    SPRENT J, 1980, 'T–B Collaboration in Vivo: Role of the Major Histocompatibility Complex', in Regulatory T Lymphocytes, Elsevier, pp. 201 - 219, http://dx.doi.org/10.1016/b978-0-12-551860-4.50018-4
    Book Chapters | 1980
    Professor Jonathan Sprent
    Sprent J, 1980, 'H-2-RESTRICTED PRESENTATION OF ANTIGEN TO T HELPER CELLS IN VIVO11Supported by USPHS Grants AI-10961, CA-15822 and AI-15393.', in Macrophage Regulation of Immunity, Elsevier, pp. 97 - 106, http://dx.doi.org/10.1016/b978-0-12-708550-0.50014-9
    Book Chapters | 1978
    Professor Jonathan Sprent
    Sprent J, 1978, 'THREE SITUATIONS IN WHICH HELPER T CELLS FAIL TO COLLABORATE WITH H2-NONIDENTICAL B CELLS', in Ir Genes and Ia Antigens, Elsevier, pp. 341 - 350, http://dx.doi.org/10.1016/b978-0-12-483260-2.50040-9
  • Journal articles | 2021
    Professor Jonathan Sprent
    Xie M; Yunis J; Yao Y; Shi J; Yang Y; Zhou P; Liang K; Wan Y; Mehdi A; Chen Z; Wang N; Xu S; Zhou M; Yu M; Wang K; Tao Y; Zhou Y; Li X; Liu X; Yu X; Wei Y; Liu Z; Sprent J; Yu D, 2021, 'High levels of soluble CD25 in COVID-19 severity suggest a divergence between anti-viral and pro-inflammatory T-cell responses', Clinical and Translational Immunology, vol. 10, http://dx.doi.org/10.1002/cti2.1251
    Journal articles | 2021
    Professor Jonathan Sprent
    King C; Sprent J, 2021, 'Dual Nature of Type I Interferons in SARS-CoV-2-Induced Inflammation', Trends in Immunology, vol. 42, pp. 312 - 322, http://dx.doi.org/10.1016/j.it.2021.02.003
    Journal articles | 2021
    Professor Jonathan Sprent
    Sprent J; King C, 2021, 'COVID-19 vaccine side effects: The positives about feeling bad', Science Immunology, vol. 6, http://dx.doi.org/10.1126/sciimmunol.abj9256
    Journal articles | 2021
    Professor Jonathan Sprent
    Pilat N; Sprent J, 2021, 'Treg Therapies Revisited: Tolerance Beyond Deletion', Frontiers in Immunology, vol. 11, http://dx.doi.org/10.3389/fimmu.2020.622810
    Journal articles | 2021
    Professor Jonathan Sprent
    Kawabe T; Yi J; Sprent J, 2021, 'Homeostasis of Naive and Memory T Lymphocytes.', Cold Spring Harb Perspect Biol, http://dx.doi.org/10.1101/cshperspect.a037879
    Journal articles | 2020
    Professor Jonathan Sprent
    Yi J; Kawabe T; Sprent J, 2020, 'New insights on T-cell self-tolerance', Current Opinion in Immunology, vol. 63, pp. 14 - 20, http://dx.doi.org/10.1016/j.coi.2019.10.002
    Journal articles | 2020
    Professor Jonathan Sprent
    Lee JY; Lee E; Hong SW; Kim D; Eunju O; Sprent J; Im SH; Lee YJ; Surh CD, 2020, 'TCB2, a new anti-human interleukin-2 antibody, facilitates heterodimeric IL-2 receptor signaling and improves anti-tumor immunity', OncoImmunology, vol. 9, http://dx.doi.org/10.1080/2162402X.2019.1681869
    Journal articles | 2019
    Professor Jonathan Sprent
    Hong SW; Eunju O; Lee JY; Lee M; Han D; Ko HJ; Sprent J; Surh CD; Kim KS, 2019, 'Food antigens drive spontaneous IgE elevation in the absence of commensal microbiota', Science Advances, vol. 5, http://dx.doi.org/10.1126/sciadv.aaw1507
    Journal articles | 2019
    Professor Jonathan Sprent
    Yi J; Jung J; Hong SW; Lee JY; Han D; Kim KS; Sprent J; Surh CD, 2019, 'Unregulated antigen-presenting cell activation by T cells breaks self tolerance', Proceedings of the National Academy of Sciences of the United States of America, vol. 116, pp. 1007 - 1016, http://dx.doi.org/10.1073/pnas.1818624116
    Journal articles | 2019
    Professor Jonathan Sprent
    Pilat N; Wiletel M; Weijler AM; Steiner R; Mahr B; Warren J; Corpuz TM; Wekerle T; Webster KE; Sprent J, 2019, 'Treg-mediated prolonged survival of skin allografts without immunosuppression', Proceedings of the National Academy of Sciences of the United States of America, vol. 116, pp. 13508 - 13516, http://dx.doi.org/10.1073/pnas.1903165116
    Journal articles | 2018
    Professor Jonathan Sprent
    Cho JH; Sprent J, 2018, 'TCR tuning of T cell subsets', Immunological Reviews, vol. 283, pp. 129 - 137, http://dx.doi.org/10.1111/imr.12646
    Journal articles | 2018
    Professor Jonathan Sprent
    Jin D; Sprent J, 2018, 'GM-CSF Culture Revisited: Preparation of Bulk Populations of Highly Pure Dendritic Cells from Mouse Bone Marrow', Journal of Immunology, vol. 201, pp. 3129 - 3139, http://dx.doi.org/10.4049/jimmunol.1800031
    Journal articles | 2018
    Professor Jonathan Sprent
    Lee JY; Kim J; Yi J; Kim D; Kim HO; Han D; Sprent J; Lee YJ; Surh CD; Cho JH, 2018, 'Phenotypic and functional changes of peripheral Ly6C+ T regulatory cells driven by conventional effector T cells', Frontiers in Immunology, vol. 9, http://dx.doi.org/10.3389/fimmu.2018.00437
    Journal articles | 2018
    Professor Jonathan Sprent
    Verma R; Lee C; Jeun EJ; Yi J; Kim KS; Ghosh A; Byun S; Lee CG; Kang HJ; Kim GC; Jun CD; Jan G; Suh CH; Jung JY; Sprent J; Rudra D; De Castro C; Molinaro A; Surh CD; Im SH, 2018, 'Cell surface polysaccharides of Bifidobacterium bifidum induce the generation of Foxp3+ regulatory T cells', Science Immunology, vol. 3, http://dx.doi.org/10.1126/sciimmunol.aat6975
    Journal articles | 2018
    Professor Jonathan Sprent
    Surh CD; Sprent J, 2018, 'T-cell apoptosis detected in situ during positive and negative selection in the thymus', Journal of Immunology, vol. 201, pp. 7 - 10
    Journal articles | 2017
    Professor Jonathan Sprent
    Loetsch C; Warren J; Laskowski A; Vazquez-Lombardi R; Jandl C; Langley DB; Christ D; Thorburn DR; Ryugo DK; Sprent J; Batten M; King C, 2017, 'Cytosolic Recognition of RNA Drives the Immune Response to Heterologous Erythrocytes', Cell Reports, vol. 21, pp. 1624 - 1638, http://dx.doi.org/10.1016/j.celrep.2017.10.044
    Journal articles | 2017
    Professor Jonathan Sprent
    Sprent J, 2017, 'T cell-B cell collaboration', Nature Reviews Immunology, vol. 17, pp. 532, http://dx.doi.org/10.1038/nri.2017.62
    Journal articles | 2017
    Professor Jonathan Sprent
    Vazquez-Lombardi R; Loetsch C; Zinkl D; Jackson J; Schofield P; Deenick EK; King C; Phan TG; Webster KE; Sprent J; Christ D, 2017, 'Potent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of regulatory T-cells', Nature Communications, vol. 8, http://dx.doi.org/10.1038/ncomms15373
    Journal articles | 2017
    Professor Jonathan Sprent
    Kurosawa M; Arakaki R; Yamada A; Tsunematsu T; Kudo Y; Sprent J; Ishimaru N, 2017, 'NF-κB2 Controls the Migratory Activity of Memory T Cells by Regulating Expression of CXCR4 in a Mouse Model of Sjögren's Syndrome', Arthritis and Rheumatology, vol. 69, pp. 2193 - 2202, http://dx.doi.org/10.1002/art.40230
    Journal articles | 2017
    Professor Jonathan Sprent
    Corpuz TM; Vazquez-Lombardi R; Luong JK; Warren J; Stolp J; Christ D; King C; Brink R; Sprent J; Webster KE, 2017, 'IL-2 shapes the survival and plasticity of IL-17-producing γδ T Cells', Journal of Immunology, vol. 199, pp. 2366 - 2376, http://dx.doi.org/10.4049/jimmunol.1700335
    Journal articles | 2017
    Professor Jonathan Sprent
    Sprent J; Surh CD, 2017, 'Writer's block: Preventing m 6 A mRNA methylation promotes T cell naivety', Immunology and Cell Biology, vol. 95, pp. 855 - 856, http://dx.doi.org/10.1038/icb.2017.67
    Journal articles | 2017
    Professor Jonathan Sprent
    Jandl C; Liu SM; Cañete PF; Warren J; Hughes WE; Vogelzang A; Webster K; Craig ME; Uzel G; Dent A; Stepensky P; Keller B; Warnatz K; Sprent J; King C, 2017, 'IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2', Nature Communications, vol. 8, http://dx.doi.org/10.1038/ncomms14647
    Journal articles | 2016
    Professor Jonathan Sprent
    Cho JH; Kim HO; Ju YJ; Kye YC; Lee GW; Lee SW; Yun CH; Bottini N; Webster K; Goodnow CC; Surh CD; King C; Sprent J, 2016, 'CD45-mediated control of TCR tuning in naïve and memory CD8+ T cells', Nature Communications, vol. 7, http://dx.doi.org/10.1038/ncomms13373
    Journal articles | 2016
    Professor Jonathan Sprent
    Pinget GV; Corpuz TM; Stolp J; Lousberg EL; Diener KR; Robertson SA; Sprent J; Webster KE, 2016, 'The majority of murine γδ T cells at the maternal-fetal interface in pregnancy produce IL-17', Immunology and Cell Biology, vol. 94, pp. 623 - 630, http://dx.doi.org/10.1038/icb.2016.48
    Journal articles | 2016
    Professor Jonathan Sprent
    Corpuz TM; Stolp J; Kim HO; Pinget GV; Gray DHD; Cho JH; Sprent J; Webster KE, 2016, 'Differential responsiveness of innate-like IL-17- and IFN-γ- producing γδ T cells to homeostatic cytokines', Journal of Immunology, vol. 196, pp. 645 - 654, http://dx.doi.org/10.4049/jimmunol.1502082
    Journal articles | 2015
    Professor Jonathan Sprent
    Kwak CW; Son YM; Gu MJ; Kim G; Lee IK; Kye YC; Kim HW; Song KD; Chu H; Park BC; Lee HK; Yang DC; Sprent J; Yun CH, 2015, 'A bacterial metabolite, compound K, induces programmed necrosis in MCF-7 cells via GSK3β', Journal of Microbiology and Biotechnology, vol. 25, pp. 1170 - 1176, http://dx.doi.org/10.4014/jmb.1505.05057
    Journal articles | 2014
    Professor Jonathan Sprent
    Webster KE; Kim HO; Kyparissoudis K; Corpuz TM; Pinget GV; Uldrich AP; Brink R; Belz GT; Cho JH; Godfrey DI; Sprent J, 2014, 'IL-17-producing NKT cells depend exclusively on IL-7 for homeostasis and survival', Mucosal Immunology, vol. 7, pp. 1058 - 1067, http://dx.doi.org/10.1038/mi.2013.122
    Journal articles | 2014
    Professor Jonathan Sprent
    Vogelzang A; McGuire HM; Liu SM; Gloss B; Mercado K; Earls P; Dinger ME; Batten M; Sprent J; King C, 2014, 'IL-21 contributes to fatal inflammatory disease in the absence of Foxp3+ T regulatory cells', Journal of Immunology, vol. 192, pp. 1404 - 1414, http://dx.doi.org/10.4049/jimmunol.1302285
    Journal articles | 2013
    Professor Jonathan Sprent
    Cho JH; Kim HO; Kim KS; Yang DH; Surh CD; Sprent J, 2013, 'Unique features of naive CD8+ T cell activation by IL-2', Journal of Immunology, vol. 191, pp. 5559 - 5573, http://dx.doi.org/10.4049/jimmunol.1302293
    Journal articles | 2013
    Professor Jonathan Sprent
    Sprent J, 2013, 'The power of dilution: Using adoptive transfer to study TCR transgenic T cells', Journal of Immunology, vol. 191, pp. 5325 - 5326, http://dx.doi.org/10.4049/jimmunol.1302679
    Journal articles | 2013
    Professor Jonathan Sprent
    Lee EM; Hurh S; Cho B; Oh KH; Kim SU; Surh CD; Sprent J; Yang J; Kim JY; Ahn C, 2013, 'CD70-CD27 ligation between neural stem cells and CD4+ T cells induces Fas-FasL-mediated T-cell death', Stem Cell Research and Therapy, vol. 4, http://dx.doi.org/10.1186/scrt206
    Journal articles | 2012
    Professor Jonathan Sprent
    Sprent J; Surh CD, 2012, 'Interleukin 7, maestro of the immune system', Seminars in Immunology, vol. 24, pp. 149 - 150, http://dx.doi.org/10.1016/j.smim.2012.04.011
    Journal articles | 2012
    Professor Jonathan Sprent
    Boyman O; Krieg C; Letourneau S; Webster KE; Surh CD; Sprent J, 2012, 'Selectively expanding subsets of T cells in mice by injection of interleukin-2/antibody complexes: Implications for transplantation tol', Transplantation Proceedings, vol. 44, pp. 1032 - 1034, http://dx.doi.org/10.1016/j.transproceed.2012.01.093
    Journal articles | 2012
    Professor Jonathan Sprent
    Polhill TS; Zhang G; Hu M; Sawyer A; Zhou J; Saito M; Webster KE; Wang Y; Wang Y; Grey ST; Sprent J; Harris DJ; Alexander SP; Wang Y, 2012, 'IL-2/IL-2Ab complexes induce regulatory T cell expansion and protect against proteinuric CKD', Journal of the American Society of Nephrology, vol. 23, pp. 1303 - 1308, http://dx.doi.org/10.1681/ASN.2011111130
    Journal articles | 2012
    Professor Jonathan Sprent
    Chang PP; Lee SK; Hu X; Davey G; Duan G; Cho JH; Karupiah G; Sprent J; Heath WR; Bertram EM; Vinuesa C, 2012, 'Breakdown in repression of IFN-gamma mRNA leads to accumulation of self-reactive effector CD8+ T cells', Journal of Immunology, vol. 189, pp. 701 - 710, http://dx.doi.org/10.4049/jimmunol.1102432
    Journal articles | 2012
    Professor Jonathan Sprent
    Boyman O; Krieg C; Homann D; Sprent J, 2012, 'Homeostatic maintenance of T cells and natural killer cells', CMLS - Cellular and Molecular Life Sciences, vol. 69, pp. 1597 - 1608, http://dx.doi.org/10.1007/s00018-012-0968-7
    Journal articles | 2012
    Professor Jonathan Sprent
    Boyman O; Sprent J, 2012, 'The role of interleukin-2 during homeostasis and activation of the immune system', Nature Reviews Immunology, vol. 12, pp. 180 - 190, http://dx.doi.org/10.1038/nri3156
    Journal articles | 2012
    Professor Jonathan Sprent
    Loebbermann J; Thornton H; Durant L; Sparwasser T; Webster KE; Sprent J; Culley FJ; Johansson C; Openshaw P, 2012, 'Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection', Mucosal Immunology, vol. 5, pp. 161 - 172, http://dx.doi.org/10.1038/mi.2011.62
    Journal articles | 2012
    Professor Jonathan Sprent
    Joo SY; Chung YS; Choi B; Kim M; Kim J-H; Jun T-G; Chang J; Sprent J; Surh CD; Jon J-W; Kim SW, 2012, 'Systemic human T cell developmental processes in humanized mice cotransplanted with human fetal thymus/liver tissue and hematopoietic stem cells', Transplantation, vol. 94, pp. 1095 - 1102, http://dx.doi.org/10.1097/TP.0b013e318270f392
    Journal articles | 2012
    Professor Jonathan Sprent
    King C; Sprent J, 2012, 'Emerging cellular networks for regulation of T follicular helper cells', Trends in Immunology, vol. 33, pp. 59 - 65, http://dx.doi.org/10.1016/j.it.2011.11.006
    Journal articles | 2012
    Professor Jonathan Sprent
    Surh CD; Sprent J, 2012, 'TGF-β puts the brakes on homeostatic proliferation', Nature Immunology, vol. 13, pp. 628 - 630, http://dx.doi.org/10.1038/ni.2345
    Journal articles | 2011
    Professor Jonathan Sprent
    McGuire HM; Walters SN; Vogelzang A; Lee CM; Webster KE; Sprent J; Christ DU; Grey S; King C, 2011, 'Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models', Diabetes, vol. 60, pp. 867 - 875, http://dx.doi.org/10.2337/db10-1157
    Journal articles | 2011
    Professor Jonathan Sprent
    Sprent J; Surh CD, 2011, 'Normal T cell homeostasis: the conversaion of naive cells into memory phenotype cells', Nature Immunology, vol. 131, pp. 478 - 484, http://dx.doi.org/10.1038/ni.2018
    Journal articles | 2011
    Professor Jonathan Sprent
    Yabas M; Teh C; Frankenreiter S; Lal D; Roots CM; Whittle B; Andrews DT; Zhang Y; Teoh NC; Sprent J; Tze LE; Kucharska E; Kofler J; Farell GC; Broer S; Goodnow CC; Enders A, 2011, 'ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes', Nature Immunology, vol. 12, pp. 441 - 452, http://dx.doi.org/10.1038/ni.2011
    Journal articles | 2011
    Professor Jonathan Sprent
    Yamano T; Watanabe S; Hasegawa H; Suzuki T; Abe R; Tahara H; Nitta T; Ishimaru N; Sprent J; Kishimoto H, 2011, 'Ex vivo-expanded DCs induce donor-specific central and peripheral tolerance and prolong the acceptance of donor skin grafts', Blood, vol. 117, pp. 2640 - 2648, http://dx.doi.org/10.1182/blood-2010-07-293860
    Journal articles | 2011
    Professor Jonathan Sprent
    Cho JH; Kim KS; Hahm B; Farell GC; Surh C; Sprent J; Roots CM; Nitta T, 2011, 'Dendritic cell internailisation of alpha-galactsylceramide from CD8 T cells induces potent antitumor CD8 T-cell responses', Cancer research, vol. 71, pp. 7442 - 7451, http://dx.doi.org/10.1158/0008-5472.CAN-11-1459
    Journal articles | 2011
    Professor Jonathan Sprent
    Wang YM; Polhill T; Zhang G; Hu M; Zhou JH; Saito M; Webster KE; Wang Y; Wang Y; Sprent J; Harris DC; Alexander SI, 2011, 'IL-2AB/IL-2 COMPLEXES INDUCE REGULATORY T CELL EXPANSION LIMITING CHRONIC PROTEINURIC RENAL INJURY', NEPHROLOGY, vol. 16, pp. 66 - 66, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000294977600164&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2010
    Professor Jonathan Sprent
    Boyman O; Cho J; Sprent J, 2010, 'The role of interleukin-2 in memory CD8 cell differentiation', Advances in Experimental Medicine and Biology, vol. 684, pp. 28 - 41, http://dx.doi.org/10.1007/978-1-4419-6451-9_3
    Journal articles | 2010
    Professor Jonathan Sprent
    Letourneau S; van Leeuwen E; Krieg C; Pantaleo G; Sprent J; Surh CD, 2010, 'IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25', Proceedings of the National Academy of Sciences of the United States of America, vol. 107, pp. 2171-6, http://dx.doi.org/10.1073/pnas.0909384107
    Journal articles | 2010
    Professor Jonathan Sprent
    Cho J; Kim H; Surh CD; Sprent J, 2010, 'T cell receptor-dependent regulation of lipid rafts controls naive CD8+ T cell homeostasis', Immunity, vol. 32, pp. 214 - 226, http://dx.doi.org/10.1016/j.immuni.2009.11.014
    Journal articles | 2010
    Professor Jonathan Sprent
    Martin CE; Kim DM; Sprent J; Surh CD, 2010, 'Is IL-7 from dendritic cells essential for the homeostasis of CD4+ T cells?', Nature Immunology, vol. 11, pp. 547-8; author reply 548, http://dx.doi.org/10.1038/ni0710-547
    Journal articles | 2010
    Professor Jonathan Sprent
    Surh CD; Sprent J, 2010, 'Glimpsing the real CD4+ T cell response', Nature Immunology, vol. 11, pp. 47-9, http://dx.doi.org/10.1038/ni0110-47
    Journal articles | 2009
    Professor Jonathan Sprent
    McGuire HM; Vogelzang A; Hill N; Flodstrom-Tullberg M; Sprent J; King C, 2009, 'Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus', Proceedings of the National Academy of Sciences of the United States of America, vol. 106, pp. 19438 - 19443, http://dx.doi.org/10.1073/pnas.0903561106
    Journal articles | 2009
    Professor Jonathan Sprent
    Boyman O; Letourneau S; Krieg C; Sprent J, 2009, 'Homeostatic proliferation and survival of naive and memory T cells', European Journal of Immunology, vol. 39, pp. 2088 - 2094, http://dx.doi.org/10.1002/eji.200939444
    Journal articles | 2009
    Professor Jonathan Sprent
    Webster K; Walters S; Kohler R; Mrkvan T; Boyman O; Surh C; Grey S; Sprent J, 2009, 'In vivo expansion of t reg cells with il-2-mab complexes: induction of resistance to eae and long-term acceptance of islet allografts without immunosuppression', Journal of Experimental Medicine, vol. 206, pp. 751 - 760, http://dx.doi.org/10.1084/jem.20082824
    Journal articles | 2009
    Professor Jonathan Sprent
    Walters SN; Webster K; Sutherland AP; Gardam S; Groom JR; Liuwantara D; Marino E; Thaxton J; Weinberg A; Mackay F; Brink R; Sprent J; Grey S, 2009, 'Increased CD4+Foxp3+ T cells in BAFF-transgenic mice suppress T cell effector responses', Journal of Immunology, vol. 182, pp. 793 - 801, http://dx.doi.org/10.4049/jimmunol.182.2.793
    Journal articles | 2009
    Professor Jonathan Sprent
    van Leeuwen E; Sprent J; Surh C, 2009, 'Generation and maintenance of memory CD4+ T Cells', Current Opinion in Immunology, vol. 21, pp. 167 - 172, http://dx.doi.org/10.1016/j.coi.2009.02.005
    Journal articles | 2009
    Professor Jonathan Sprent
    Sprent J; Surh C, 2009, 'Re-entry of mature T cells to the thymus: An epiphenomenon?', Immunology and Cell Biology, vol. 87, pp. 46 - 49, http://dx.doi.org/10.1038/icb.2008.88
    Journal articles | 2009
    Professor Jonathan Sprent
    Vogelzang A; McGuire H; Sprent J; King C, 2009, 'A fundamental role for Interleukin-21 in germinal center antibody responses', JOURNAL OF IMMUNOLOGY, vol. 182, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209763600130&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2008
    Professor Jonathan Sprent
    Sprent J; Cho J; Boyman O; Surh C, 2008, 'T cell homeostasis', Immunology and Cell Biology, vol. 86, pp. 312 - 319, http://dx.doi.org/10.1038/icb.2008.12
    Journal articles | 2008
    Professor Jonathan Sprent
    Vogelzang A; McGuire H; Yu D; Sprent J; MacKay CR; King CK, 2008, 'A fundamental role for interleukin-21 in the generation of T follicular helper cells', Immunity, vol. 29, pp. 127 - 137, http://dx.doi.org/10.1016/j.immuni.2008.06.001
    Journal articles | 2008
    Professor Jonathan Sprent
    Ramsey C; Rubinstein M; Kim DH; Cho J; Sprent J; Surh C, 2008, 'The lymphopenic environment of CD132 (common gamma-chain)-deficient hosts elicits rapid homeostatic proliferation of naive T cells via IL-15', Journal of Immunology, vol. 180, pp. 5320 - 5326
    Journal articles | 2008
    Professor Jonathan Sprent
    Boyman O; Ramsey C; Kim DH; Sprent J; Surh C, 2008, 'IL-7/Anti-IL-7 mAb complexes restore T cell development and induce homeostatic T cell expansion without lymphopenia', Journal of Immunology, vol. 180, pp. 7265 - 7275, http://dx.doi.org/10.4049/jimmunol.180.11.7265
    Journal articles | 2008
    Professor Jonathan Sprent
    Surh C; Sprent J, 2008, 'Homeostasis of Naive and Memory T Cells', Immunity, vol. 29, pp. 848 - 862, http://dx.doi.org/10.1016/j.immuni.2008.11.002
    Journal articles | 2008
    Professor Jonathan Sprent
    Sprent J; Cho J, 2008, 'Self/non-self discrimination and the problem of keeping T cells alive', Immunology and Cell Biology, vol. 86, pp. 54 - 56, http://dx.doi.org/10.1038/sj.icb.7100139
    Journal articles | 2008
    Professor Jonathan Sprent
    Kim K; Wang L; Sprent J; Hwang I, 2008, 'Detection and Direct Stimulation of Antigen-specific T cells by Nanometric Membrane Vesicles Expressing pMHC Complexes', FASEB JOURNAL, vol. 22, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208467700413&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2008
    Professor Jonathan Sprent
    Wang L; Kim K; Boger DL; Sprent J; Hwang I, 2008, 'Systematic approach to explore molecular mechanism for TCR‐mediated LFA‐1 activation: Modulation of TCR signaling by AMP‐activated protein kinase', The FASEB Journal, vol. 22, pp. 652 - 652, http://dx.doi.org/10.1096/fasebj.22.2_supplement.652
    Journal articles | 2008
    Professor Jonathan Sprent
    Webster K; Walters S; Mrkvan T; Boyman O; Grey S; Sprent J, 2008, 'ALLOGRAFT TOLERANCE AFTER IN VIVO EXPANSION OF TREGS WITH IL-2/IL-2 MAB COMPLEXES', Transplantation, vol. 86, pp. 8 - 8, http://dx.doi.org/10.1097/01.tp.0000332700.58733.14
    Journal articles | 2007
    Professor Jonathan Sprent
    Tough DF; Sprent J; Stephens GL, 2007, 'Measurement of T and B cell turnover with bromodeoxyuridine.', Current protocols in immunology / edited by John E. Coligan ... [et al.], vol. Chapter 4, http://dx.doi.org/10.1002/0471142735.im0407s77
    Journal articles | 2007
    Professor Jonathan Sprent
    Cho J; Boyman O; Kim H; Hahm B; Rubinstein M; Ramsey C; Kim D; Surh C; Sprent J, 2007, 'An intense form of homeostatic proliferation of naive CD8(+) cells driven by IL-2', Journal of Experimental Medicine, vol. 204, pp. 1787 - 1801, http://dx.doi.org/10.1084/jem.20070740
    Journal articles | 2007
    Professor Jonathan Sprent
    Purton J; Tan J; Rubinstein M; Kim D; Sprent J; Surh C, 2007, 'Antiviral CD4(+) memory T cells are IL-15 dependent', Journal of Experimental Medicine, vol. 204, pp. 951 - 961, http://dx.doi.org/10.1084/jem.20061805
    Journal articles | 2007
    Professor Jonathan Sprent
    Boyman O; Purton J; Surh C; Sprent J, 2007, 'Cytokines and T-cell homeostasis', Current Opinion in Immunology, vol. 19, pp. 320 - 326, http://dx.doi.org/10.1016/j.coi.2007.04.015
    Journal articles | 2007
    Professor Jonathan Sprent
    Purton J; Sprent J; Surh C, 2007, 'Staying alive - naive CD4(+) T cell homeostasis', European Journal of Immunology, vol. 37, pp. 2367 - 2369, http://dx.doi.org/10.1002/eji.200737721
    Journal articles | 2007
    Professor Jonathan Sprent
    Ishimaru N; Kishimoto H; Hayashi Y; Sprent J, 2007, 'Erratum: Corrigendum: Regulation of naive T cell function by the NF-κB pathway', Nature Immunology, vol. 8, pp. 1266 - 1266, http://dx.doi.org/10.1038/ni1107-1266b
    Journal articles | 2007
    Professor Jonathan Sprent
    Ishimaru N; Kishimoto H; Hayashi Y; Sprent J, 2007, 'Erratum: Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes (Nature Immunology (2007) vol. 8 (835-844))', Nature Immunology, vol. 8, pp. 1266, http://dx.doi.org/10.1038/ni1107-1266a
    Journal articles | 2007
    Professor Jonathan Sprent
    Rubinstein M; Sprent J; Goldrath A, 2007, 'Augmenting CD8+ T cell responses with IL-15/sIL-15R alpha complexes', Clinical Immunology, vol. 123, pp. S162 - S163, http://dx.doi.org/10.1016/j.clim.2007.03.102
    Journal articles | 2006
    Professor Jonathan Sprent
    McKay D; Shigeoka A; Rubinstein M; Surh C; Sprent J, 2006, 'Simultaneous deletion of MyD88 and Trif delays major histocompatibility and minor antigen mismatch allograft rejection', European Journal of Immunology, vol. 36, pp. 1994 - 2002, http://dx.doi.org/10.1002/eji.200636249
    Journal articles | 2006
    Professor Jonathan Sprent
    Boyman O; Surh CD; Sprent J, 2006, 'Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease', Expert Opinion on Biological Therapy, vol. 6, pp. 1323 - 1331, http://dx.doi.org/10.1517/14712598.6.12.1323
    Journal articles | 2006
    Professor Jonathan Sprent
    Surh C; Boyman O; Purton J; Sprent J, 2006, 'Homeostasis of memory T cells', Immunological Reviews, vol. 211, pp. 154 - 163, http://dx.doi.org/10.1111/j.0105-2896.2006.00401.x
    Journal articles | 2006
    Professor Jonathan Sprent
    Rubinstein M; Kovar M; Purton J; Cho J; Boyman O; Surh C; Sprent J, 2006, 'Converting IL-15 to a superagonist by binding to soluble IL-15R alpha', Proceedings of the National Academy of Sciences of the United States of America, vol. 103, pp. 9166 - 9171, http://dx.doi.org/10.1073/pnas.0600240103
    Journal articles | 2006
    Professor Jonathan Sprent
    Boyman O; Kovar M; Rubinstein M; Surh C; Sprent J, 2006, 'Selective stimulation of T cell subsets with antibody-cytokine immune complexes', Science, vol. 311, pp. 1924 - 1927, http://dx.doi.org/10.1126/science.1122927
    Journal articles | 2006
    Professor Jonathan Sprent
    Ishimaru N; Kishimoto H; Hayashi Y; Sprent J, 2006, 'Regulation of naive T cell function by the NF-kappa B2 pathway', Nature Immunology, vol. 7, pp. 763 - 772, http://dx.doi.org/10.1038/ni1351
    Journal articles | 2006
    Professor Jonathan Sprent
    Boyman O; Cho J; Tan JH; Surh C; Sprent J, 2006, 'A major histocompatibility complex class I-dependent subset of memory phenotype CD8(+) cells', Journal of Experimental Medicine, vol. 203, pp. 1817 - 1825, http://dx.doi.org/10.1084/jem.20052495
    Journal articles | 2006
    Professor Jonathan Sprent
    Kovar M; Boyman O; Shen XC; Hwang I; Kohler R; Sprent J, 2006, 'Direct stimulation of T cells by membrane vesicles from antigen-presenting cells', Proceedings of the National Academy of Sciences of the United States of America, vol. 103, pp. 11671 - 11676, http://dx.doi.org/10.1073/pnas.0603466103
    Journal articles | 2006
    Professor Jonathan Sprent
    Zambricki E; Zal T; Yachi P; Shigeoka A; Sprent J; Gascoigne N; McKay D, 2006, 'In vivo anergized T cells form altered immunological synapses in vitro', American Journal of Transplantation, vol. 6, pp. 2572 - 2579, http://dx.doi.org/10.1111/j.1600-6143.2006.01517.x
    Journal articles | 2006
    Professor Jonathan Sprent
    Surh CD; Sprent J, 2006, 'Erratum: On the TRAIL of homeostatic memory T cells (Nature Immunology (2006) vol. 7 (439-441))', Nature Immunology, vol. 7, pp. 672, http://dx.doi.org/10.1038/ni0606-672b
    Journal articles | 2006
    Professor Jonathan Sprent
    Sprent J; Miller JF; Mitchell GF, 2006, 'Antigen-induced selective recruitment of circulating lymphocytes', Journal of Immunology, vol. 177, pp. 1381 - 1391
    Journal articles | 2005
    Professor Jonathan Sprent
    Kolumam GA; Thomas S; Thompson LJ; Sprent J; Murali-Krishna K, 2005, 'Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection', Journal of Experimental Medicine, vol. 202, pp. 637 - 650, http://dx.doi.org/10.1084/jem.20050821
    Journal articles | 2005
    Professor Jonathan Sprent
    Surh CD; Sprent J, 2005, 'Regulation of mature T cell homeostasis', Seminars in Immunology, vol. 17, pp. 183 - 191, http://dx.doi.org/10.1016/j.smim.2005.02.007
    Journal articles | 2005
    Professor Jonathan Sprent
    Sprent J, 2005, 'Direct stimulation of naïve T cells by antigen-presenting cell vesicles', Blood Cells, Molecules, and Diseases, vol. 35, pp. 17 - 20, http://dx.doi.org/10.1016/j.bcmd.2005.04.004
    Journal articles | 2005
    Professor Jonathan Sprent
    Goodnow CC; Sprent J; Barbara BF; Vinuesa CG, 2005, 'Cellular and genetic mechanisms of self tolerance and autoimmunity', Nature, vol. 435, pp. 590 - 597, http://dx.doi.org/10.1038/nature03724
    Journal articles | 2005
    Professor Jonathan Sprent
    Zambricki E; Shigeoka A; Kishimoto H; Sprent J; Burakoff S; Carpenter C; Milford E; McKay D, 2005, 'Signaling T-cell survival and death by IL-2 and IL-15', American Journal of Transplantation, vol. 5, pp. 2623 - 2631, http://dx.doi.org/10.1111/j.1600-6143.2005.01075.x
    Journal articles | 2005
    Professor Jonathan Sprent
    Sprent J, 2005, 'Swapping molecules during cell-cell interactions.', Science's STKE : signal transduction knowledge environment, vol. 2005, http://dx.doi.org/10.1126/stke.2732005pe8
    Journal articles | 2005
    Professor Jonathan Sprent
    Sprent J, 2005, 'Proving negative selection in the thymus', Journal of Immunology, vol. 174, pp. 3841 - 3842, http://dx.doi.org/10.4049/jimmunol.174.7.3841
    Journal articles | 2005
    Professor Jonathan Sprent
    Cancro MP; Sprent J, 2005, 'Counting on homeostasis: Governing the size and composition of lymphocyte pools', Seminars in Immunology, vol. 17, pp. 173, http://dx.doi.org/10.1016/j.smim.2005.02.009
    Journal articles | 2004
    Professor Jonathan Sprent
    Lenz DC; Kurz SK; Lemmens E; Schoenberger SP; Sprent J; Oldstone MBA; Homann D, 2004, 'IL-7 regulates basal homeostatic proliferation of antiviral CD4 +T cell memory', Proceedings of the National Academy of Sciences of the United States of America, vol. 101, pp. 9357 - 9362, http://dx.doi.org/10.1073/pnas.0400640101
    Journal articles | 2003
    Professor Jonathan Sprent
    Villunger A; Marsden VS; Strasser A; Kishimoto H; Sprent J, 2003, 'Efficient T cell receptor-mediated apoptosis in nonobese diabetic mouse thymocytes (multiple letters)', Nature Immunology, vol. 4, pp. 717 - 718, http://dx.doi.org/10.1038/ni0803-717
    Journal articles | 2003
    Professor Jonathan Sprent
    Hwang I; Shen X; Sprent J, 2003, 'Direct stimulation of naïve T cells by membrane vesicles from antigen-presenting cells: Distinct roles for CD54 and B7 molecules', Proceedings of the National Academy of Sciences of the United States of America, vol. 100, pp. 6670 - 6675, http://dx.doi.org/10.1073/pnas.1131852100
    Journal articles | 2003
    Professor Jonathan Sprent
    Sprent J; Surh CD, 2003, 'Knowing one's self: Central tolerance revisited', Nature Immunology, vol. 4, pp. 303 - 304, http://dx.doi.org/10.1038/ni0403-303
    Journal articles | 2003
    Professor Jonathan Sprent
    Sprent J, 2003, 'Turnover of memory-phenotype CD8+ T cells', Microbes and Infection, vol. 5, pp. 227 - 231, http://dx.doi.org/10.1016/S1286-4579(03)00015-7
    Journal articles | 2003
    Professor Jonathan Sprent
    Sprent J; Surh CD, 2003, 'Cytokines and T cell homeostasis', Immunology Letters, vol. 85, pp. 145 - 149, http://dx.doi.org/10.1016/S0165-2478(02)00221-3
    Journal articles | 2003
    Professor Jonathan Sprent
    Kishimoto H; Sprent J, 2003, 'Response to 'Efficient T cell receptor–mediated apoptosis in nonobese diabetic mouse thymocytes'', Nature Immunology, vol. 4, pp. 718 - 718, http://dx.doi.org/10.1038/ni0803-718
    Journal articles | 2002
    Professor Jonathan Sprent
    Sprent J; Kishimoto H, 2002, 'The thymus and negative selection', Immunological Reviews, vol. 185, pp. 126 - 135, http://dx.doi.org/10.1034/j.1600-065X.2002.18512.x
    Journal articles | 2002
    Professor Jonathan Sprent
    Judge AD; Zhang X; Fujii H; Surh CD; Sprent J, 2002, 'Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8+ T cells', Journal of Experimental Medicine, vol. 196, pp. 935 - 946, http://dx.doi.org/10.1084/jem.20020772
    Journal articles | 2002
    Professor Jonathan Sprent
    Tan JT; Ernst B; Kieper WC; LeRoy E; Sprent J; Surh CD, 2002, 'Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells', Journal of Experimental Medicine, vol. 195, pp. 1523 - 1532, http://dx.doi.org/10.1084/jem.20020066
    Journal articles | 2002
    Professor Jonathan Sprent
    Zhang X; Fujii H; Kishimoto H; LeRoy E; Surh CD; Sprent J, 2002, 'Aging leads to disturbed homeostasis of memory phenotype CD8+ cells', Journal of Experimental Medicine, vol. 195, pp. 283 - 293, http://dx.doi.org/10.1084/jem.20011267
    Journal articles | 2002
    Professor Jonathan Sprent
    Kieper WC; Tan JT; Bondi-Boyd B; Gapin L; Sprent J; Ceredig R; Surh CD, 2002, 'Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells', Journal of Experimental Medicine, vol. 195, pp. 1533 - 1539, http://dx.doi.org/10.1084/jem.20020067
    Journal articles | 2002
    Professor Jonathan Sprent
    Surh CD; Sprent J, 2002, 'Regulation of naïve and memory T-cell homeostasis', Microbes and Infection, vol. 4, pp. 51 - 56, http://dx.doi.org/10.1016/S1286-4579(01)01509-X
    Journal articles | 2002
    Professor Jonathan Sprent
    Sprent J; Judge AD; Zhang X, 2002, 'Cytokines and memory-phenotype CD8+ cells', Advances in Experimental Medicine and Biology, vol. 512, pp. 147 - 153, http://dx.doi.org/10.1007/978-1-4615-0757-4_20
    Journal articles | 2002
    Professor Jonathan Sprent
    Sprent J; Uittenbogaart CH; Fink PJ, 2002, 'A season for midwinter immunology', Nature Immunology, vol. 3, pp. 414 - 416, http://dx.doi.org/10.1038/ni0502-414
    Journal articles | 2002
    Professor Jonathan Sprent
    Sprent J, 2002, 'T memory cells: Quality not quantity', Current Biology, vol. 12, http://dx.doi.org/10.1016/S0960-9822(02)00735-2
    Journal articles | 2001
    Professor Jonathan Sprent
    Hwang I; Sprent J, 2001, 'Role of the actin cytoskeleton in T cell absorption and internalization of ligands from APC1', Journal of Immunology, vol. 166, pp. 5099 - 5107, http://dx.doi.org/10.4049/jimmunol.166.8.5099
    Journal articles | 2001
    Professor Jonathan Sprent
    Sprent J; Surh CD, 2001, 'Generation and maintenance of memory T cells', Current Opinion in Immunology, vol. 13, pp. 248 - 254, http://dx.doi.org/10.1016/S0952-7915(00)00211-9
    Journal articles | 2001
    Professor Jonathan Sprent
    Tan JT; Dudl E; LeRoy E; Murray R; Sprent J; Weinberg KI; Surh CD, 2001, 'IL-7 is critical for homeostatic proliferation and survival of naïve T cells', Proceedings of the National Academy of Sciences of the United States of America, vol. 98, pp. 8732 - 8737, http://dx.doi.org/10.1073/pnas.161126098
    Journal articles | 2001
    Professor Jonathan Sprent
    Kishimoto H; Sprent J, 2001, 'A defect in central tolerance in NOD mice', Nature Immunology, vol. 2, pp. 1025 - 1031, http://dx.doi.org/10.1038/ni726
    Journal articles | 2001
    Professor Jonathan Sprent
    Sprent J; Tough DF, 2001, 'T cell death and memory', Science, vol. 293, pp. 245 - 248, http://dx.doi.org/10.1126/science.1062416
    Journal articles | 2001
    Professor Jonathan Sprent
    Tough DF; Zhang X; Sprent J, 2001, 'An IFN-γ-dependent pathway controls stimulation of memory phenotype CD8+ T cell turnover in vivo by IL-12, IL-18, and IFN-γ1', Journal of Immunology, vol. 166, pp. 6007 - 6011, http://dx.doi.org/10.4049/jimmunol.166.10.6007
    Journal articles | 2001
    Professor Jonathan Sprent
    Sprent J, 2001, 'T-cell survival and the role of cytokines', Immunology and Cell Biology, vol. 79, pp. 199 - 206, http://dx.doi.org/10.1046/j.1440-1711.2001.00999.x
    Journal articles | 2001
    Professor Jonathan Sprent
    Sprent J; Kishimoto H, 2001, 'The thymus and central tolerance', Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 356, pp. 609 - 616, http://dx.doi.org/10.1098/rstb.2001.0846
    Journal articles | 2000
    Professor Jonathan Sprent
    Hwang I; Huang JF; Kishimoto H; Brunmark A; Peterson PA; Jackson MR; Surh CD; Zeling C; Sprent J, 2000, 'T cells can use either T cell receptor or CD28 receptors to absorb and internalize cell surface molecules derived from antigen-presenting cells', Journal of Experimental Medicine, vol. 191, pp. 1137 - 1148, http://dx.doi.org/10.1084/jem.191.7.1137
    Journal articles | 2000
    Professor Jonathan Sprent
    Kishimoto H; Sprent J, 2000, 'The thymus and negative selection', Immunologic Research, vol. 21, pp. 315 - 323, http://dx.doi.org/10.1385/ir:21:2-3:315
    Journal articles | 2000
    Professor Jonathan Sprent
    Sprent J; Zhang X; Sun S; Tough D, 2000, 'T-cell proliferation in vivo and the role of cytokines', Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 355, pp. 317 - 322, http://dx.doi.org/10.1098/rstb.2000.0568
    Journal articles | 2000
    Professor Jonathan Sprent
    Tough DF; Sun S; Zhang X; Sprent J, 2000, 'Stimulation of memory T cells by cytokines', Vaccine, vol. 18, pp. 1642 - 1648, http://dx.doi.org/10.1016/S0264-410X(99)00500-9
    Journal articles | 2000
    Professor Jonathan Sprent
    Sun S; Zhang X; Tough D; Sprent J, 2000, 'Multiple effects of immunostimulatory DNA on T cells and the role of type I interferons', Springer Seminars in Immunopathology, vol. 22, pp. 77 - 84, http://dx.doi.org/10.1007/s002810000028
    Journal articles | 2000
    Professor Jonathan Sprent
    Surh CD; Sprent J, 2000, 'Homeostatic T cell proliferation: How far can T cells be activated to self-ligands?', Journal of Experimental Medicine, vol. 192, http://dx.doi.org/10.1084/jem.192.4.F9
    Journal articles | 1999
    Professor Jonathan Sprent
    Ernst B; Lee DS; Chang JM; Sprent J; Surh CD, 1999, 'The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery', Immunity, vol. 11, pp. 173 - 181, http://dx.doi.org/10.1016/S1074-7613(00)80092-8
    Journal articles | 1999
    Professor Jonathan Sprent
    Huang JF; Yang Y; Sepulveda H; Shi W; Hwang I; Peterson PA; Jackson MR; Sprent J; Cai Z, 1999, 'TCR-mediated internalization of peptide-MHC complexes acquired by T cells', Science, vol. 286, pp. 952 - 954, http://dx.doi.org/10.1126/science.286.5441.952
    Journal articles | 1999
    Professor Jonathan Sprent
    Tough DF; Sun S; Zhang X; Sprent J, 1999, 'Stimulation of naive and memory T cells by cytokines', Immunological Reviews, vol. 170, pp. 39 - 47, http://dx.doi.org/10.1111/j.1600-065X.1999.tb01327.x
    Journal articles | 1999
    Professor Jonathan Sprent
    Lee DS; Curie A; Ernst B; Sprent J; Surh CD, 1999, 'Thymic selection by a single MHC/peptide ligand: Autoreactive T cells are low-affinity cells', Immunity, vol. 10, pp. 83 - 92, http://dx.doi.org/10.1016/S1074-7613(00)80009-6
    Journal articles | 1999
    Professor Jonathan Sprent
    Kishimoto H; Sprent J, 1999, 'Strong TCR ligation without costimulation causes rapid onset of Fas- dependent apoptosis of naive murine CD4+ T cells', Journal of Immunology, vol. 163, pp. 1817 - 1826
    Journal articles | 1999
    Professor Jonathan Sprent
    Kishimoto H; Sprent J, 1999, 'Several different cell surface molecules control negative selection of medullary thymocytes', Journal of Experimental Medicine, vol. 190, pp. 65 - 73, http://dx.doi.org/10.1084/jem.190.1.65
    Journal articles | 1999
    Professor Jonathan Sprent
    Tough DF; Sprent J, 1999, 'Bystander stimulation of T cells by cytokines', Immunologist, vol. 7, pp. 75 - 78
    Journal articles | 1999
    Professor Jonathan Sprent
    Ahmed R; Sprent J, 1999, 'Immunological memory', Immunologist, vol. 7, pp. 23 - 26
    Journal articles | 1998
    Professor Jonathan Sprent
    Borrow P; Tough DF; Eto D; Tishon A; Grewal IS; Sprent J; Flavell RA; Oldstone MBA, 1998, 'CD40 ligand-mediated interactions are involved in the generation of memory CD8+ cytotoxic T lymphocytes (CTL) but are not required for the maintenance of CTL memory following virus infection', Journal of Virology, vol. 72, pp. 7440 - 7449, http://dx.doi.org/10.1128/jvi.72.9.7440-7449.1998
    Journal articles | 1998
    Professor Jonathan Sprent
    Zhang X; Sun S; Hwang I; Tough DF; Sprent J, 1998, 'Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15', Immunity, vol. 8, pp. 591 - 599, http://dx.doi.org/10.1016/S1074-7613(00)80564-6
    Journal articles | 1998
    Professor Jonathan Sprent
    Sun S; Zhang X; Tough DF; Sprent J, 1998, 'Type I interferon-mediated stimulation of T cells by CpG DNA', Journal of Experimental Medicine, vol. 188, pp. 2335 - 2342, http://dx.doi.org/10.1084/jem.188.12.2335
    Journal articles | 1998
    Professor Jonathan Sprent
    Sprent J; Kishimoto H, 1998, 'T cell tolerance and the thymus.', Ann N Y Acad Sci, vol. 841, pp. 236 - 245, http://dx.doi.org/10.1111/j.1749-6632.1998.tb10933.x
    Journal articles | 1998
    Professor Jonathan Sprent
    Kishimoto H; Surh CD; Sprent J, 1998, 'A role for Fas in negative selection of thymocytes in vivo', Journal of Experimental Medicine, vol. 187, pp. 1427 - 1438, http://dx.doi.org/10.1084/jem.187.9.1427
    Journal articles | 1998
    Professor Jonathan Sprent
    Tough DF; Sprent J, 1998, 'Anti-viral immunity: Spotting virus-specific T cells', Current Biology, vol. 8, http://dx.doi.org/10.1016/s0960-9822(98)70317-3
    Journal articles | 1998
    Professor Jonathan Sprent
    Tough DF; Sprent J, 1998, 'Bystander stimulation of T cells in vivo by cytokines', Veterinary Immunology and Immunopathology, vol. 63, pp. 123 - 129, http://dx.doi.org/10.1016/S0165-2427(98)00088-9
    Journal articles | 1998
    Professor Jonathan Sprent
    Belardelli F; Ferrantini M; Santini SM; Baccarini S; Proietti E; Colombo MP; Sprent J; Tough DF, 1998, 'The induction of in vivo proliferation of long-lived CD44(hi) CD8+ T cells after the injection of tumor cells expressing IFN-α1 into syngeneic mice', Cancer Research, vol. 58, pp. 5795 - 5802
    Journal articles | 1998
    Professor Jonathan Sprent
    Luxembourg AT; Brunmark A; Kong Y; Jackson MR; Peterson PA; Sprent J; Cai Z, 1998, 'Requirements for stimulating naive CD8+ T cells via signal 1 alone', Journal of Immunology, vol. 161, pp. 5226 - 5235
    Journal articles | 1998
    Professor Jonathan Sprent
    Tough DF; Sprent J, 1998, 'Lifespan of γ/δ T cells', Journal of Experimental Medicine, vol. 187, pp. 357 - 365, http://dx.doi.org/10.1084/jem.187.3.357
    Journal articles | 1998
    Professor Jonathan Sprent
    Sun S; Kishimoto H; Sprent J, 1998, 'DNA as an adjuvant: Capacity of insect DNA and synthetic oligodeoxynucleotides to augment T cell responses to specific antigen', Journal of Experimental Medicine, vol. 187, pp. 1145 - 1150, http://dx.doi.org/10.1084/jem.187.7.1145
    Journal articles | 1998
    Professor Jonathan Sprent
    Cai Z; Brunmark AB; Luxembourg AT; Garcia KC; Degano M; Teyton L; Wilson I; Peterson PA; Sprent J; Jackson MR, 1998, 'Probing the activation requirements for naive CD8+ T cells with Drosophila cell transfectants as antigen presenting cells', Immunological Reviews, vol. 165, pp. 249 - 265, http://dx.doi.org/10.1111/j.1600-065X.1998.tb01243.x
    Journal articles | 1997
    Professor Jonathan Sprent
    Sprent J; Tough DF; Sun S, 1997, 'Factors controlling the turnover of T memory cells', Immunological Reviews, vol. 156, pp. 79 - 85, http://dx.doi.org/10.1111/j.1600-065X.1997.tb00960.x
    Journal articles | 1997
    Professor Jonathan Sprent
    Surh CD; Kosaka H; Sprent J, 1997, 'Rat stem cells developing in irradiated SCID mice fail to become tolerized and cause lethal graft-versus-host disease', American Journal of Pathology, vol. 151, pp. 591 - 599
    Journal articles | 1997
    Professor Jonathan Sprent
    Kishimoto H; Sprent J, 1997, 'Negative selection in the thymus includes semimature T cells', Journal of Experimental Medicine, vol. 185, pp. 263 - 271, http://dx.doi.org/10.1084/jem.185.2.263
    Journal articles | 1997
    Professor Jonathan Sprent
    Surh CD; Lee DS; Fung-Leung WP; Karlsson L; Sprent J, 1997, 'Thymic selection by a single MHC/peptide ligand produces a semidiverse repertoire of CD4+ T cells', Immunity, vol. 7, pp. 209 - 219, http://dx.doi.org/10.1016/S1074-7613(00)80524-5
    Journal articles | 1997
    Professor Jonathan Sprent
    Tough DF; Sun S; Sprent J, 1997, 'T cell stimulation in vivo by lipopolysaccharide (LPS)', Journal of Experimental Medicine, vol. 185, pp. 2089 - 2094, http://dx.doi.org/10.1084/jem.185.12.2089
    Journal articles | 1997
    Professor Jonathan Sprent
    Cai Z; Kishimoto H; Brunmark A; Jackson MR; Peterson PA; Sprent J, 1997, 'Requirements for peptide-induced T cell receptor downregulation on naive CD8+ T cells', Journal of Experimental Medicine, vol. 185, pp. 641 - 651, http://dx.doi.org/10.1084/jem.185.4.641
    Journal articles | 1997
    Professor Jonathan Sprent
    Sun S; Beard C; Jaenisch R; Jones P; Sprent J, 1997, 'Mitogenicity of DNA from Different Organisms for Murine B Cells', Journal of Immunology, vol. 159, pp. 3119 - 3125
    Journal articles | 1997
    Professor Jonathan Sprent
    Sprent J, 1997, 'T cells and memory lapses.', Trends in microbiology, vol. 5, http://dx.doi.org/10.1016/s0966-842x(97)01072-x
    Journal articles | 1997
    Professor Jonathan Sprent
    Sprent J, 1997, 'Immunological memory', Current Opinion in Immunology, vol. 9, pp. 371 - 379, http://dx.doi.org/10.1016/S0952-7915(97)80084-2
    Journal articles | 1996
    Professor Jonathan Sprent
    Tough DF; Borrow P; Sprent J, 1996, 'Induction of bystander T cell proliferation by viruses and type I interferon in vivo', Science, vol. 272, pp. 1947 - 1950, http://dx.doi.org/10.1126/science.272.5270.1947
    Journal articles | 1996
    Professor Jonathan Sprent
    Tough DF; Sprent J, 1996, 'Viruses and T Cell Turnover: Evidence for Bystander Proliferation', Immunological Reviews, pp. 129 - 142, http://dx.doi.org/10.1111/j.1600-065x.1996.tb00699.x
    Journal articles | 1996
    Professor Jonathan Sprent
    Sun S; Cai Z; Langlade-Demoyen P; Kosaka H; Brunmark A; Jackson MR; Peterson PA; Sprent J, 1996, 'Dual function of drosophila cells as APCs for naive CD8+ T cells: Implications for tumor immunotherapy', Immunity, vol. 4, pp. 555 - 564, http://dx.doi.org/10.1016/S1074-7613(00)80482-3
    Journal articles | 1996
    Professor Jonathan Sprent
    Ernst BB; Surh CD; Sprent J, 1996, 'Bone marrow-derived cells fail to induce positive selection in thymus reaggregation cultures', Journal of Experimental Medicine, vol. 183, pp. 1235 - 1240, http://dx.doi.org/10.1084/jem.183.3.1235
    Journal articles | 1996
    Professor Jonathan Sprent
    Kishimoto H; Cai Z; Brunmark A; Jackson MR; Peterson PA; Sprent J, 1996, 'Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes', Journal of Experimental Medicine, vol. 184, pp. 531 - 537, http://dx.doi.org/10.1084/jem.184.2.531
    Journal articles | 1996
    Professor Jonathan Sprent
    Cai Z; Sprent J, 1996, 'Influence of antigen dose and costimulation on the primary response of CD8+ T cells in vitro', Journal of Experimental Medicine, vol. 183, pp. 2247 - 2257, http://dx.doi.org/10.1084/jem.183.5.2247
    Journal articles | 1996
    Professor Jonathan Sprent
    Tough DF; Sprent J, 1996, 'Measurement of T and B Cell Turnover with Bromodeoxyuridine', Current Protocols in Immunology, vol. 18, http://dx.doi.org/10.1002/0471142735.im0407s18
    Journal articles | 1995
    Professor Jonathan Sprent
    Sprent J, 1995, 'Antigen-Presenting Cells: Professionals and amateurs', Current Biology, vol. 5, pp. 1095 - 1097, http://dx.doi.org/10.1016/S0960-9822(95)00219-3
    Journal articles | 1995
    Professor Jonathan Sprent
    Ernst B; Surh CD; Sprent J, 1995, 'Thymic selection and cell division', Journal of Experimental Medicine, vol. 182, pp. 961 - 972, http://dx.doi.org/10.1084/jem.182.4.961
    Journal articles | 1995
    Professor Jonathan Sprent
    Kishimoto H; Surh CD; Sprent J, 1995, 'Upregulation of surface markers on dying thymocytes', Journal of Experimental Medicine, vol. 181, pp. 649 - 655, http://dx.doi.org/10.1084/jem.181.2.649
    Journal articles | 1995
    Professor Jonathan Sprent
    Tough DF; Sprent J, 1995, 'Life span of naive and memory t cells', STEM CELLS, vol. 13, pp. 242 - 249, http://dx.doi.org/10.1002/stem.5530130305
    Journal articles | 1995
    Professor Jonathan Sprent
    Tough DF; Sprent J, 1995, 'Lifespan of lymphocytes', Immunologic Research, vol. 14, pp. 1 - 12, http://dx.doi.org/10.1007/BF02918494
    Journal articles | 1995
    Professor Jonathan Sprent
    Sprent J; Tough D, 1995, 'CD4+ cell turnover', Nature, vol. 375, pp. 194, http://dx.doi.org/10.1038/375194a0
    Journal articles | 1995
    Professor Jonathan Sprent
    Sprent J; Hurd M; Schaefer M; Heath W, 1995, 'Split tolerance in spleen chimeras', Journal of Immunology, vol. 154, pp. 1198 - 1206
    Journal articles | 1995
    Professor Jonathan Sprent
    Tough DF; Sprent J, 1995, 'Thymic emigration - a reply', Immunology Today, vol. 16, pp. 273 - 274, http://dx.doi.org/10.1016/0167-5699(95)80180-4
    Journal articles | 1995
    Professor Jonathan Sprent
    Sprent J, 1995, 'Central tolerance of t cells', International Reviews of Immunology, vol. 13, pp. 95 - 105, http://dx.doi.org/10.3109/08830189509061740
    Journal articles | 1995
    Professor Jonathan Sprent
    Sprent J; Webb SR, 1995, 'Intrathymic and extrathymic clonal deletion of T cells', Current Opinion in Immunology, vol. 7, pp. 196 - 205, http://dx.doi.org/10.1016/0952-7915(95)80004-2
    Journal articles | 1995
    Professor Jonathan Sprent
    Sprent J; Tough D, 1995, 'CD4+ cell turnover', Nature, vol. 375, pp. 194, http://dx.doi.org/10.1038/375194a0
    Journal articles | 1995
    Professor Jonathan Sprent
    Sprent J; Tough D, 1995, 'HIV results in the frame. CD4+ cell turnover.', Nature, vol. 375
    Journal articles | 1994
    Professor Jonathan Sprent
    Gold DP; Surh CD; Sellins KS; Schroder K; Sprent J; Wilson DB, 1994, 'Rat T cell responses to superantigens. II. ailelic differences in Vβ8.2 and vβ8.5 β chains determine responsiveness to staphylococcal enterotoxin B and mouse mammary tumor virus-encoded products', Journal of Experimental Medicine, vol. 179, pp. 63 - 69, http://dx.doi.org/10.1084/jem.179.1.63
    Journal articles | 1994
    Professor Jonathan Sprent
    Surh CD; Gold DP; Wiley S; Wilson DB; Sprent J, 1994, 'Rat T cell response to superantigens. I. Vβ-restricted clonal deletion of rat T cells differentiating in rat → mouse chimeras', Journal of Experimental Medicine, vol. 179, pp. 57 - 62, http://dx.doi.org/10.1084/jem.179.1.57
    Journal articles | 1994
    Professor Jonathan Sprent
    Sprent J; Surh CD; Agus D; Hurd M; Sutton S; Heath WR, 1994, 'Profound atrophy of the bone marrow reflecting major histocompatibility complex class II-restricted destruction of stem cells by CD4+ cells', Journal of Experimental Medicine, vol. 180, pp. 307 - 317, http://dx.doi.org/10.1084/jem.180.1.307
    Journal articles | 1994
    Professor Jonathan Sprent
    Cai Z; Sprent J, 1994, 'Resting and activated t cells display different requirements for cd8 molecules', Journal of Experimental Medicine, vol. 179, pp. 2005 - 2015, http://dx.doi.org/10.1084/jem.179.6.2005
    Journal articles | 1994
    Professor Jonathan Sprent
    Sprent J; Tough DF, 1994, 'Lymphocyte life-span and memory', Science, vol. 265, pp. 1395 - 1400, http://dx.doi.org/10.1126/science.8073282
    Journal articles | 1994
    Professor Jonathan Sprent
    Surh CD; Sprent J, 1994, 'T-cell apoptosis detected in situ during positive and negative selection in the thymus', Nature, vol. 372, pp. 100 - 103, http://dx.doi.org/10.1038/372100a0
    Journal articles | 1994
    Professor Jonathan Sprent
    Vallera DA; Taylor PA; Sprent J; Blazar BR, 1994, 'The role of host t cell subsets in bone marrow rejection directed to isolated major histocompatibility complex class I versus class II differences of bm1 and bm12 mutant mice', Transplantation, vol. 57, pp. 249 - 256, http://dx.doi.org/10.1097/00007890-199401001-00017
    Journal articles | 1994
    Professor Jonathan Sprent
    Degermann S; Surh CD; Glimcher LH; Sprent J; Lo D, 1994, 'B7 expression on thymic medullary epithelium correlates with epithelium- mediated deletion of Vβ5+ thymocytes', Journal of Immunology, vol. 152, pp. 3254 - 3263
    Journal articles | 1994
    Professor Jonathan Sprent
    Webb SR; Hutchinson J; Hayden K; Sprent J, 1994, 'Expansion/deletion of mature T cells exposed to endogenous superantigens in vivo', Journal of Immunology, vol. 152, pp. 586 - 597
    Journal articles | 1994
    Professor Jonathan Sprent
    Tough DF; Sprent J, 1994, 'Turnover of naive- and memory-phenotype T cells', Journal of Experimental Medicine, vol. 179, pp. 1127 - 1135, http://dx.doi.org/10.1084/jem.179.4.1127
    Journal articles | 1994
    Professor Jonathan Sprent
    Sprent J, 1994, 'T and B memory cells', Cell, vol. 76, pp. 315 - 322, http://dx.doi.org/10.1016/0092-8674(94)90338-7
    Journal articles | 1993
    Professor Jonathan Sprent
    Sprent J, 1993, 'Lifespans of naive, memory and effector lymphocytes', Current Opinion in Immunology, vol. 5, pp. 433 - 438, http://dx.doi.org/10.1016/0952-7915(93)90065-Z
    Journal articles | 1993
    Professor Jonathan Sprent
    Sprent J; Kosaka H; Gao E; Surh CD; Webb SR, 1993, 'Intrathymic and Extrathymic Tolerance in Bone Marrow Chimeras', Immunological Reviews, vol. 133, pp. 151 - 176, http://dx.doi.org/10.1111/j.1600-065X.1993.tb01515.x
    Journal articles | 1993
    Professor Jonathan Sprent
    Kosaka H; Sprent J, 1993, 'Tolerance of CD8+ T cells developing in parent → F1 chimeras prepared with supralethal irradiation: Step-wise induction of tolerance in the intrathymic and extrathymic environments', Journal of Experimental Medicine, vol. 177, pp. 367 - 378, http://dx.doi.org/10.1084/jem.177.2.367
    Journal articles | 1993
    Professor Jonathan Sprent
    Surh CD; Sprent J; Webb SR, 1993, 'Exclusion of circulating T cells from the thymus does not apply in the neonatal period', Journal of Experimental Medicine, vol. 177, pp. 379 - 385, http://dx.doi.org/10.1084/jem.177.2.379
    Journal articles | 1993
    Professor Jonathan Sprent
    Webb SR; Sprent J, 1993, 'Factors Controlling the Reactivity of Immature and Mature T Cells to Mlsa Antigens in vivo', Immunological Reviews, vol. 131, pp. 169 - 188, http://dx.doi.org/10.1111/j.1600-065X.1993.tb01535.x
    Journal articles | 1993
    Professor Jonathan Sprent
    SPRENT J, 1993, 'The Thymus and T‐Cell Tolerance', Annals of the New York Academy of Sciences, vol. 681, pp. 5 - 15, http://dx.doi.org/10.1111/j.1749-6632.1993.tb22863.x
    Journal articles | 1993
    Professor Jonathan Sprent
    Sprent J; Kosaka H, 1993, 'T cell tolerance and self/nonself discrimination', Autoimmunity, vol. 15, pp. 155 - 161, http://dx.doi.org/10.3109/08916939309043890
    Journal articles | 1992
    Professor Jonathan Sprent
    Kosaka H; Surh CD; Sprent J, 1992, 'Stimulation of mature unprimed CD8+ T cells by semiprofessional antigen-presenting cells in vivo', Journal of Experimental Medicine, vol. 176, pp. 1291 - 1302, http://dx.doi.org/10.1084/jem.176.5.1291
    Journal articles | 1992
    Professor Jonathan Sprent
    Frey JR; Ernst B; Surh CD; Sprent J, 1992, 'Thymus-grafted SCID Mice Show Transient Thymopoiesis and Limited Depletion of Vβ 11+ T Cells', Journal of Experimental Medicine, vol. 175, pp. 1067 - 1071, http://dx.doi.org/10.1084/jem.175.4.1067
    Journal articles | 1992
    Professor Jonathan Sprent
    Surh CD; Gao EK; Kosaka H; Lo D; Ahn C; Murphy DB; Karlsson L; Peterson P; Sprent J, 1992, 'Two subsets of epithelial cells in the thymic medulla', Journal of Experimental Medicine, vol. 176, pp. 495 - 505, http://dx.doi.org/10.1084/jem.176.2.495
    Journal articles | 1992
    Professor Jonathan Sprent
    Surh CD; Ernst B; Sprent J, 1992, 'Growth of epithelial cells in the thymic medulla is under the control of mature T cells', Journal of Experimental Medicine, vol. 176, pp. 611 - 616, http://dx.doi.org/10.1084/jem.176.2.611
    Journal articles | 1992
    Professor Jonathan Sprent
    Myers KJ; Sprent J; Dougherty JP; Ron Y, 1992, 'Synergy between encephalitogenic T cells and myelin basic protein-specific antibodies in the induction of experimental autoimmune encephalomyelitis', Journal of Neuroimmunology, vol. 41, pp. 1 - 8, http://dx.doi.org/10.1016/0165-5728(92)90188-Q
    Journal articles | 1992
    Professor Jonathan Sprent
    Karlsson L; Surh CD; Sprent J; Peterson PA, 1992, 'An unusual class II molecule', Immunology Today, vol. 13, pp. 469 - 470, http://dx.doi.org/10.1016/0167-5699(92)90018-3
    Journal articles | 1992
    Professor Jonathan Sprent
    Webb SR; Hutchinson J; Sprent J, 1992, 'Mls antigens: Immunity and tolerance', Chemical Immunology, vol. 55, pp. 87 - 114
    Journal articles | 1992
    Professor Jonathan Sprent
    Webb SR; O'Rourke AM; Sprent J, 1992, 'Factors influencing the fate of T cells responding to Mls antigens', Seminars in Immunology, vol. 4, pp. 329 - 336
    Journal articles | 1992
    Professor Jonathan Sprent
    Sprent J; Webb S, 1992, 'Can self/nonself discrimination be explained entirely by clonal deletion?', Research in Immunology, vol. 143, pp. 285 - 287, http://dx.doi.org/10.1016/0923-2494(92)80121-Z
    Journal articles | 1991
    Professor Jonathan Sprent
    Sprent J; Schaefer M; Hurd M; Surh CD; Ron Y, 1991, 'Mature murine B and T cells transferred to SCID mice can survive indefinitely and many maintain a virgin phenotype', Journal of Experimental Medicine, vol. 174, pp. 717 - 728, http://dx.doi.org/10.1084/jem.174.3.717
    Journal articles | 1991
    Professor Jonathan Sprent
    Gao EK; Kosaka H; Surh CD; Sprent J, 1991, 'T cell contact with ia antigens on nonhemopoietic cells in vivo can lead to immunity rather than tolerance', Journal of Experimental Medicine, vol. 174, pp. 435 - 446, http://dx.doi.org/10.1084/jem.174.2.435
    Journal articles | 1991
    Professor Jonathan Sprent
    Murphy GF; Whitaker D; Sprent J; Korngold R, 1991, 'Characterization of target injury of murine acute graft-versus-host disease directed to multiple minor histocompatibility antigens elicited by either CD4+ or CD8+ effector cells', American Journal of Pathology, vol. 138, pp. 983 - 990
    Journal articles | 1991
    Professor Jonathan Sprent
    Agus DB; Surh CD; Sprent J, 1991, 'Reentry of T cells to the adult thymus is restricted to activated T cells', Journal of Experimental Medicine, vol. 173, pp. 1039 - 1046, http://dx.doi.org/10.1084/jem.173.5.1039
    Journal articles | 1991
    Professor Jonathan Sprent
    Korngold R; Sprent J, 1991, 'Graft-Versus-Host Disease in Experimental Allogeneic Bone Marrow Transplantation', Proceedings of the Society for Experimental Biology and Medicine, vol. 197, pp. 12 - 18, http://dx.doi.org/10.3181/00379727-197-43217A
    Journal articles | 1991
    Professor Jonathan Sprent
    Karlsson L; Surh CD; Sprent J; Peterson PA, 1991, 'A novel class II MHC molecule with unusual tissue distribution', Nature, vol. 351, pp. 485 - 488, http://dx.doi.org/10.1038/351485a0
    Journal articles | 1991
    Professor Jonathan Sprent
    Surh CD; Sprent J, 1991, 'Long-term xenogeneic chimeras: Full differentiation of rat T and B cells in SCID mice', Journal of Immunology, vol. 147, pp. 2148 - 2154
    Journal articles | 1990
    Professor Jonathan Sprent
    Gao E; Lo D; Sprent J, 1990, 'Strong T cell tolerance in parent - F1 bone marrow chimeras prepared with supralethal irradiation: Evidence for clonal deletion and anergy', Journal of Experimental Medicine, vol. 171, pp. 1101 - 1121, http://dx.doi.org/10.1084/jem.171.4.1101
    Journal articles | 1990
    Professor Jonathan Sprent
    Webb SR; Sprent J, 1990, 'Tolerogenicity of thymic epithelium', European Journal of Immunology, vol. 20, pp. 2525 - 2528, http://dx.doi.org/10.1002/eji.1830201127
    Journal articles | 1990
    Professor Jonathan Sprent
    Webb SR; Sprent J, 1990, 'Response of mature unprimed CD8+ T cells to Mlsa determinants', Journal of Experimental Medicine, vol. 171, pp. 953 - 958, http://dx.doi.org/10.1084/jem.171.3.953
    Journal articles | 1990
    Professor Jonathan Sprent
    Sprent J; Schaefer M, 1990, 'Antigen‐presenting Cells for CD8+ T Cells', Immunological Reviews, vol. 117, pp. 213 - 234, http://dx.doi.org/10.1111/j.1600-065X.1990.tb00574.x
    Journal articles | 1990
    Professor Jonathan Sprent
    Sprent J; Schaeffer M; Korngold R, 1990, 'Role of T cell subsets in lethal graft-versus-host disease (GVHD) directed to class I versus class II H-2 differences. II. Protective effects of L3T4+ cells in anti-class II GVHD', Journal of Immunology, vol. 144, pp. 2946 - 2954
    Journal articles | 1990
    Professor Jonathan Sprent
    Webb S; Morris C; Sprent J, 1990, 'Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity', Cell, vol. 63, pp. 1249 - 1256, http://dx.doi.org/10.1016/0092-8674(90)90420-J
    Journal articles | 1990
    Professor Jonathan Sprent
    Webb SR; Sprent J, 1990, 'Induction of neonatal tolerance to Mlsa antigens by CD8 + T cells', Science, vol. 248, pp. 1643 - 1646, http://dx.doi.org/10.1126/science.1973003
    Journal articles | 1990
    Professor Jonathan Sprent
    Sprent J; Gao EK; Webb SR, 1990, 'T cell reactivity to MHC molecules: Immunity versus tolerance', Science, vol. 248, pp. 1357 - 1363, http://dx.doi.org/10.1126/science.1694041
    Journal articles | 1990
    Professor Jonathan Sprent
    Gray D; Sprent J, 1990, 'Immunological memory: Preface', Current Topics in Microbiology and Immunology, vol. 159
    Journal articles | 1989
    Professor Jonathan Sprent
    Webb SR; Sprent J, 1989, 'T‐Cell Responses and Tolerance to Mlsa Determinants', Immunological Reviews, vol. 107, pp. 141 - 158, http://dx.doi.org/10.1111/j.1600-065X.1989.tb00007.x
    Journal articles | 1989
    Professor Jonathan Sprent
    Gao EK; Kanagawa O; Sprent J, 1989, 'Capacity of unprimed CD4+ and CD8+ T cells expressing Vβll receptors to respond to I-E alloantigens in vivo', Journal of Experimental Medicine, vol. 170, pp. 1947 - 1957, http://dx.doi.org/10.1084/jem.170.6.1947
    Journal articles | 1989
    Professor Jonathan Sprent
    Sprent J; Schaefer M, 1989, 'Antigen-presenting cells for Lyt-2+ cells. II. Primary mixed-lymphocyte reactions stimulated by la+ dendritic cells and la -peritoneal exudate cells', International Immunology, vol. 1, pp. 517 - 525, http://dx.doi.org/10.1093/intimm/1.5.517
    Journal articles | 1989
    Professor Jonathan Sprent
    Webb SR; Okamoto A; Ron Y; Sprent J, 1989, 'Restricted tissue distribution of M1sa determinants. Stimulation of M1sa-reactive T cells by B cells but not by dendritic cells or macrophages', Journal of Experimental Medicine, vol. 169, pp. 1 - 12, http://dx.doi.org/10.1084/jem.169.1.1
    Journal articles | 1989
    Professor Jonathan Sprent
    Mowat AMI; Sprent J, 1989, 'Induction of intestinal graft-versus-host reactions across mutant major histocompatibility antigens by T lymphocyte subsets in mice', Transplantation, vol. 47, pp. 857 - 863, http://dx.doi.org/10.1097/00007890-198905000-00022
    Journal articles | 1989
    Professor Jonathan Sprent
    Sprent J; Schaefer M, 1989, 'Antigen-presenting cells for unprimed T cells', Immunology Today, vol. 10, pp. 17 - 23, http://dx.doi.org/10.1016/0167-5699(89)90060-1
    Journal articles | 1989
    Professor Jonathan Sprent
    Korngold R; Sprent J, 1989, 'Selective allogeneic donor T cell subsets in experimental bone marrow transplantation', Transplantation Proceedings, vol. 21, pp. 2940 - 2942
    Journal articles | 1989
    Professor Jonathan Sprent
    Lawrance SK; Karlsson L; Price J; Quaranta V; Ron Y; Sprent J; Peterson PA, 1989, 'Transgenic HLA-DRα faithfully reconstitutes IE-controlled immune functions and induces cross-tolerance to Eα in Eα0 mutant mice', Cell, vol. 58, pp. 583 - 594, http://dx.doi.org/10.1016/0092-8674(89)90439-X
    Journal articles | 1988
    Professor Jonathan Sprent
    Sprent J; Lo D; Gao E; Ron Y, 1988, 'T Cell Selection in the Thymus', Immunological Reviews, vol. 101, pp. 173 - 190, http://dx.doi.org/10.1111/j.1600-065X.1988.tb00737.x
    Journal articles | 1988
    Professor Jonathan Sprent
    Sprent J; Schaefer M; Gao EK; Korngold R, 1988, 'Role of T cell subsets in lethal graft-versus-host disease (GVHD) directed to class I versus class II h-2 differences I. L3T4+ cells can either augment or retard gvhd elicited by lyt-2+ cells in class I-different hosts', Journal of Experimental Medicine, vol. 167, pp. 556 - 569, http://dx.doi.org/10.1084/jem.167.2.556
    Journal articles | 1988
    Professor Jonathan Sprent
    Webb SR; Okamoto A; Sprent J, 1988, 'Mls DETERMINANTS AND ANTI‐Mls RECEPTORS', International Journal of Immunogenetics, vol. 15, pp. 111 - 120, http://dx.doi.org/10.1111/j.1744-313X.1988.tb00413.x
    Journal articles | 1988
    Professor Jonathan Sprent
    Webb SR; Okamoto A; Sprent J, 1988, 'Analysis of T hybridomas prepared from a T cell clone with three specificities: Recognition of self + X and allo-H-2 determinants segregates from recognition of Mlsa determinants', Journal of Immunology, vol. 141, pp. 1828 - 1834
    Journal articles | 1988
    Professor Jonathan Sprent
    Sprent J; Schaefer M, 1988, 'Capacity of purified unprimed Lyt-2+ cells to reject Ia- H-2-different tumor cells in the Winn assay', Journal of Immunology, vol. 140, pp. 2899 - 2902
    Journal articles | 1988
    Professor Jonathan Sprent
    Gao EK; Lo D; Cheney R; Kanagawa O; Sprent J, 1988, 'Abnormal differentiation of thymocytes in mice treated with cyclosporin A', Nature, vol. 336, pp. 176 - 179, http://dx.doi.org/10.1038/336176a0
    Journal articles | 1988
    Professor Jonathan Sprent
    Sprent J; Schaefer M, 1988, 'Antigen-presenting cells for Lyt-2+ cells: I. Stimulation of unprimed Lyt-2+ cells by H-2 different Thy-1- Ia- cells prepared from spleen and bone marrow', Journal of Immunology, vol. 140, pp. 3745 - 3750
    Journal articles | 1988
    Professor Jonathan Sprent
    Sprent J; Gao EK; Kanagawa O; Webb SR, 1988, 'T-cell selection in the thymus.', Princess Takamatsu symposia, vol. 19, pp. 127 - 136
    Journal articles | 1987
    Professor Jonathan Sprent
    Korngold R; Sprent J, 1987, 'T cell subsets and graft-versus-host disease', Transplantation, vol. 44, pp. 335 - 339, http://dx.doi.org/10.1097/00007890-198709000-00002
    Journal articles | 1987
    Professor Jonathan Sprent
    Sprent J; Webb SR, 1987, 'Function and Specificity of T Cell Subsets in the Mouse', Advances in Immunology, vol. 41, pp. 39 - 133, http://dx.doi.org/10.1016/S0065-2776(08)60030-9
    Journal articles | 1987
    Professor Jonathan Sprent
    Korngold R; Sprent J, 1987, 'Variable capacity of L3T4+ T cells to cause lethal graft-versus-host disease across minor histocompatibility barriers in mice', Journal of Experimental Medicine, vol. 165, pp. 1552 - 1564, http://dx.doi.org/10.1084/jem.165.6.1552
    Journal articles | 1987
    Professor Jonathan Sprent
    Webb S; Sprent J, 1987, 'Downregulation of T cell responses by antibodies to the T cell receptor', Journal of Experimental Medicine, vol. 165, pp. 584 - 589, http://dx.doi.org/10.1084/jem.165.2.584
    Journal articles | 1987
    Professor Jonathan Sprent
    Ron Y; Sprent J, 1987, 'T cell priming in vivo: A major role for B cells in presenting antigen to T cells in lymph nodes', Journal of Immunology, vol. 138, pp. 2848 - 2856
    Journal articles | 1987
    Professor Jonathan Sprent
    Sprent J; Korngold R, 1987, 'T cell subsets controlling graft-v-host disease in mice', Transplantation Proceedings, vol. 19, pp. 41 - 47
    Journal articles | 1987
    Professor Jonathan Sprent
    Ron Y; Isakov N; Sprent J, 1987, 'Unresponsiveness of MRL/MP-lpr/lpr mice to antigen given subcutaneously in adjuvant: Partial restoration of response after local injection of B cells', Journal of Immunology, vol. 139, pp. 400 - 405
    Journal articles | 1986
    Professor Jonathan Sprent
    Sprent J; Schaefer M; Lo D; Korngold R, 1986, 'Properties of purified T cell subsets: II. in vivo responses to class I VS. class II H-2 differences', Journal of Experimental Medicine, vol. 163, pp. 998 - 1011, http://dx.doi.org/10.1084/jem.163.4.998
    Journal articles | 1986
    Professor Jonathan Sprent
    Sprent J; Schaefer M; Lo D; Kornoo R, 1986, 'Functions of Purified L3T4+ and Lyt‐2+ Cells in vitro and in vivo', Immunological Reviews, vol. 91, pp. 195 - 218, http://dx.doi.org/10.1111/j.1600-065X.1986.tb01489.x
    Journal articles | 1986
    Professor Jonathan Sprent
    Sprent J; Schaefer M, 1986, 'Capacity of purified Lyt-2+ T cells to mount primary proliferative and cytotoxic responses to Ia- tumour cells.', Nature, vol. 322, pp. 541 - 544, http://dx.doi.org/10.1038/322541a0
    Journal articles | 1986
    Professor Jonathan Sprent
    Lo D; Sprent J, 1986, 'Identity of cells that imprint H-2-restricted T-cell specificity in the thymus', Nature, vol. 319, pp. 672 - 675, http://dx.doi.org/10.1038/319672a0
    Journal articles | 1986
    Professor Jonathan Sprent
    Ron Y; Lo D; Sprent J, 1986, 'T cell specificity in twice-irradiated F1→parent bone marrow chimeras: Failure to detect a role for immigrant marrow-derived cells in imprinting intrathymic H-2 restriction', Journal of Immunology, vol. 137, pp. 1764 - 1771
    Journal articles | 1986
    Professor Jonathan Sprent
    Lo D; Sprent J, 1986, 'Exogenous control of I-A expression in fetal thymus explants', Journal of Immunology, vol. 137, pp. 1772 - 1775
    Journal articles | 1986
    Professor Jonathan Sprent
    Webb SR; Sprent J, 1986, 'T cells with multiple specificities', International Reviews of Immunology, vol. 1, pp. 151 - 182, http://dx.doi.org/10.3109/08830188609056605
    Journal articles | 1986
    Professor Jonathan Sprent
    Lo D; Ron Y; Sprent J, 1986, 'Induction of MHC-restricted specificity and tolerance in the thymus', Immunologic Research, vol. 5, pp. 221 - 232, http://dx.doi.org/10.1007/BF02919203
    Journal articles | 1985
    Professor Jonathan Sprent
    Ron Y; Sprent J, 1985, 'Prolonged survival in vivo of unprimed b cells responsive to a t-independent antigen', Journal of Experimental Medicine, vol. 161, pp. 1581 - 1586, http://dx.doi.org/10.1084/jem.161.6.1581
    Journal articles | 1985
    Professor Jonathan Sprent
    Sprent J; Schaefer M, 1985, 'Properties of purified T cell subsets: I. in vitro responses to class I vs. class II H-2 alloantigens', Journal of Experimental Medicine, vol. 162, pp. 2068 - 2088, http://dx.doi.org/10.1084/jem.162.6.2068
    Journal articles | 1985
    Professor Jonathan Sprent
    Webb SR; Huli J; MacNeil I; Marrack P; Sprent J; Wilson DB, 1985, 'T cell receptors for responses to Mls determinants and allo-H-2 determinants appear to be encoded on different chromosomes', Journal of Experimental Medicine, vol. 161, pp. 269 - 274, http://dx.doi.org/10.1084/jem.161.1.269
    Journal articles | 1985
    Professor Jonathan Sprent
    Webb SR; Li JH; Wilson DB; Sprent J, 1985, 'Capacity of small B cell‐enriched populations to stimulate mixed lymphocyte reactions: marked differences between irradiated vs. mitomycin C‐treated stimulators', European Journal of Immunology, vol. 15, pp. 92 - 96, http://dx.doi.org/10.1002/eji.1830150118
    Journal articles | 1985
    Professor Jonathan Sprent
    Korngold R; Sprent J, 1985, 'Surface markers of T cells causing lethal graft-vs-host disease to class I vs class II H-2 differences', Journal of Immunology, vol. 135, pp. 3004 - 3010
    Journal articles | 1985
    Professor Jonathan Sprent
    Sprent J; Bruce J; Ron Y; Webb SR, 1985, 'Physiology of B cells in mice with X-linked immunodeficiency. I. Size, migratory properties, and turnover of the B cell pool', Journal of Immunology, vol. 134, pp. 1442 - 1448
    Journal articles | 1985
    Professor Jonathan Sprent
    Cheney RT; Sprent J, 1985, 'Capacity of cyclosporine to induce auto-graft-versus-host disease and impair intrathymic T cell differentiation', Transplantation Proceedings, vol. 17, pp. 528 - 530
    Journal articles | 1985
    Professor Jonathan Sprent
    Sprent J, 1985, 'Major histocompatibility complex restriction and T cell specificity: What's new?', Transplantation Proceedings, vol. 17, pp. 937 - 943
    Journal articles | 1984
    Professor Jonathan Sprent
    Sprent J; Bruce J, 1984, 'Physiology of B cells in mice with x-linked immunodeficiency: II. Influence of the thymus and mature T cells on B cell differentiation', Journal of Experimental Medicine, vol. 160, pp. 335 - 340, http://dx.doi.org/10.1084/jem.160.1.335
    Journal articles | 1984
    Professor Jonathan Sprent
    Sprent J; Bruce J, 1984, 'Physiology of B cells in mice with X-linked immunodeficiency (XID): III. Disappearance of xid B cells in double bone marrow chimeras', Journal of Experimental Medicine, vol. 160, pp. 711 - 723, http://dx.doi.org/10.1084/jem.160.3.711
    Journal articles | 1984
    Professor Jonathan Sprent
    Sprent J, 1984, 'T/B collaboration in vivo vs. in vitro', Annales de l'Institut Pasteur - Immunology, vol. 135, pp. 98 - 105, http://dx.doi.org/10.1016/S0769-2625(84)80164-6
    Journal articles | 1984
    Professor Jonathan Sprent
    Webb SR; Mosier DE; Wilson DB; Sprent J, 1984, 'Negative selection in vivo reveals expression of strong mis determinants in mice with x-linked immunodeficiency', Journal of Experimental Medicine, vol. 160, pp. 108 - 115, http://dx.doi.org/10.1084/jem.160.1.108
    Journal articles | 1984
    Professor Jonathan Sprent
    Sprent J, 1984, 'T/B collaboration in vivo vs. in vitro', Annales de l'Institut Pasteur - Immunology, vol. 135, pp. 120 - 127, http://dx.doi.org/10.1016/S0769-2625(84)80085-9
    Journal articles | 1984
    Professor Jonathan Sprent
    Sprent J, 1984, 'Helper cells for in vitro primary antibody response: a commentary', Journal of Molecular and Cellular Immunology, vol. 1, pp. 221 - 222
    Journal articles | 1983
    Professor Jonathan Sprent
    Korngold R; Sprent J, 1983, 'Lethal graft-versus-host disease across minor histocompatibility barriers in mice', Clinics in Haematology, vol. 12, pp. 681 - 693, http://dx.doi.org/10.1016/S0308-2261(83)80005-8
    Journal articles | 1983
    Professor Jonathan Sprent
    Korngold R; Sprent J, 1983, 'Lethal GVHD Across Minor Histocompatibility Barriers: Nature of the Effector Cells and Role of the H‐2 Complex', Immunological Reviews, vol. 71, pp. 5 - 30, http://dx.doi.org/10.1111/j.1600-065X.1983.tb01066.x
    Journal articles | 1982
    Professor Jonathan Sprent
    Korngold R; Sprent J, 1982, 'Features of T cells causing H-2-restricted lethal graft-vs.-host disease across minor histocompatibility barriers', Journal of Experimental Medicine, vol. 155, pp. 872 - 883, http://dx.doi.org/10.1084/jem.155.3.872
    Journal articles | 1982
    Professor Jonathan Sprent
    Alpert B; Sprent J, 1982, 'Role of the H-2 complex in induction of T helper cells in vivo. III. contribution of the I-E subregion to restriction sites recognized by I-A/E-restricted T cells', Journal of Experimental Medicine, vol. 155, pp. 548 - 556, http://dx.doi.org/10.1084/jem.155.2.548
    Journal articles | 1982
    Professor Jonathan Sprent
    Sprent J; Alpert B; Bruce J, 1982, 'The role of I-A and I-E gene products in T helper cell induction in vivo', Behring Institute Mitteilungen, vol. No. 70, pp. 83 - 89
    Journal articles | 1982
    Professor Jonathan Sprent
    Alpert B; Sprent J, 1982, 'Negative selection of discrete subgroups of T helper cells restricted by determinants present on I-A and I-A/E molecules.', Advances in experimental medicine and biology, vol. 149, pp. 623 - 627, http://dx.doi.org/10.1007/978-1-4684-9066-4_86
    Journal articles | 1982
    Professor Jonathan Sprent
    Symington FW; Subbarao B; Mosier DE; Sprent J, 1982, 'Lyb-8.2: A new B cell antigen defined and characterized with a monoclonal antibody', Immunogenetics, vol. 16, pp. 381 - 391, http://dx.doi.org/10.1007/BF00372098
    Journal articles | 1982
    Professor Jonathan Sprent
    Sprent J; Korngold R, 1982, 'H-2-restriction of T cells mediating lethal graft-versus-host-disease to minor histocompatibility determinants.', Advances in experimental medicine and biology, vol. 149, pp. 531 - 536, http://dx.doi.org/10.1007/978-1-4684-9066-4_74
    Journal articles | 1981
    Professor Jonathan Sprent
    Webb SR; Molnar-Kimber K; Bruce J; Sprent J; Wilson DB, 1981, 'T cell clones with dual specificity for M1s and various major histocompatibility complex determinants', Journal of Experimental Medicine, vol. 154, pp. 1970 - 1974, http://dx.doi.org/10.1084/jem.154.6.1970
    Journal articles | 1981
    Professor Jonathan Sprent
    Molnar-Kimber KL; Sprent J, 1981, 'Evidence that strong Mls determinants are nonpolymorphic', Transplantation, vol. 31, pp. 376, http://dx.doi.org/10.1097/00007890-198105010-00014
    Journal articles | 1981
    Professor Jonathan Sprent
    Symington FW; Sprent J, 1981, 'A monoclonal antibody detecting an Ia specificity mapping in the I-A or I-E subregion', Immunogenetics, vol. 14, pp. 53 - 61, http://dx.doi.org/10.1007/BF00344299
    Journal articles | 1981
    Professor Jonathan Sprent
    Bruce J; Symington FW; McKearn TJ; Sprent J, 1981, 'A monoclonal antibody discriminating between subsets of T and B cells', Journal of Immunology, vol. 127, pp. 2496 - 2501
    Journal articles | 1981
    Professor Jonathan Sprent
    Sprent J; Alpert B, 1981, 'Role of the H-2 complex in induction of T helper cells in vivo. II. Negative selection of discrete subgroups of T cells restricted by I-A and I-A/E determinants', Journal of Experimental Medicine, vol. 153, pp. 823 - 831, http://dx.doi.org/10.1084/jem.153.4.823
    Journal articles | 1981
    Professor Jonathan Sprent
    Sprent J; Lerner EA; Bruce J; Symington FW, 1981, 'Inhibition of T cell activation in vivo with mixtures of monoclonal antibodies specific for I-A and I-A/E molecules', Journal of Experimental Medicine, vol. 154, pp. 188 - 192, http://dx.doi.org/10.1084/jem.154.1.188
    Journal articles | 1981
    Professor Jonathan Sprent
    Sprent J; Korngold R, 1981, 'Immunogenetics of graft-versus-host reactions to minor histocompatibility antigens', Immunology Today, vol. 2, pp. 189 - 195, http://dx.doi.org/10.1016/0167-5699(81)90070-0
    Journal articles | 1981
    Professor Jonathan Sprent
    Korngold R; Sprent J, 1981, 'H-2 restriction of T cells causing lethal graft-versus-host disease across minor histocompatibility barriers in mice', Transplantation Proceedings, vol. 13, pp. 1217 - 1219
    Journal articles | 1980
    Professor Jonathan Sprent
    Sprent J, 1980, 'Features of cells controlling H-2-restricted presentation of antigen to T helper cells in vivo', Journal of Immunology, vol. 125, pp. 2089 - 2096
    Journal articles | 1980
    Professor Jonathan Sprent
    Korngold R; Sprent J, 1980, 'Negative selection of T cells causing lethal graft-versus-host disease across minor histocompatibility barriers. Role of the H-2 complex', Journal of Experimental Medicine, vol. 151, pp. 1114 - 1124, http://dx.doi.org/10.1084/jem.151.5.1114
    Journal articles | 1980
    Professor Jonathan Sprent
    Sprent J, 1980, 'Effects of blocking helper T cell induction in vivo with anti-Ia antibodies. Possible role of I-A/E hybrid molecules as restriction elements', Journal of Experimental Medicine, vol. 152, pp. 996 - 1010, http://dx.doi.org/10.1084/jem.152.4.996
    Journal articles | 1980
    Professor Jonathan Sprent
    Sprent J, 1980, 'Antigen-induced selective sequestration of T lymphocytes: role of the major histocompatibility complex.', Monographs in allergy, vol. 16, pp. 233 - 244
    Journal articles | 1980
    Professor Jonathan Sprent
    Molnar-Kimber KL; Webb SR; Sprent J; Wilson DB, 1980, 'T cell lines with dual specificity for strong Mls and H-2 determinants', Journal of Immunology, vol. 125, pp. 2643 - 2645
    Journal articles | 1980
    Professor Jonathan Sprent
    Sprent J; Korngold R; Molnar-Kimber K, 1980, 'T cell recognition of antigen in vivo: Role of the H-2 complex', Springer Seminars in Immunopathology, vol. 3, pp. 213 - 245, http://dx.doi.org/10.1007/BF02053976
    Journal articles | 1980
    Professor Jonathan Sprent
    Molnar-Kimber K; Sprent J, 1980, 'Absence of H-2 restriction in primary and secondary mixed-lymphocyte reactions to strong M1s determinants', Journal of Experimental Medicine, vol. 151, pp. 407 - 412, http://dx.doi.org/10.1084/jem.151.2.407
    Journal articles | 1980
    Professor Jonathan Sprent
    Korngold R; Sprent J, 1980, 'Selection of cytotoxic T-cell precursors specific for minor histocompatibility determinants. I. Negative selection across H-2 barriers induced with disrupted cells but not with glutaraldehyde-treated cells: Evidence for antigen processing', Journal of Experimental Medicine, vol. 151, pp. 314 - 327, http://dx.doi.org/10.1084/jem.151.2.314
    Journal articles | 1979
    Professor Jonathan Sprent
    Sprent J; Von Boehmer H, 1979, 'T-helper function of parent → F1 chimeras: Presence of a separate T-cell subgroup able to stimulate allogeneic B cells but not syngeneic B cells', Journal of Experimental Medicine, vol. 149, pp. 387 - 397, http://dx.doi.org/10.1084/jem.149.2.387
    Journal articles | 1979
    Professor Jonathan Sprent
    Sprent J; Bruce J, 1979, 'Lymphoid function in F1 → parent chimeras: Lack of evidence for adaptive differentiation of B cells or antigen-presenting cells', Journal of Experimental Medicine, vol. 150, pp. 715 - 720, http://dx.doi.org/10.1084/jem.150.3.715
    Journal articles | 1978
    Professor Jonathan Sprent
    Korngold R; Sprent J, 1978, 'Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice: Prevention by removing mature T cells from marrow*', Journal of Experimental Medicine, vol. 148, pp. 1687 - 1698, http://dx.doi.org/10.1084/jem.148.6.1687
    Journal articles | 1978
    Professor Jonathan Sprent
    Sprent J, 1978, 'Two subgroups of T helper cells in F1 hybrid mice revealed by negative selection to heterologous erythrocytes in vivo', Journal of Immunology, vol. 121, pp. 1691 - 1695
    Journal articles | 1978
    Professor Jonathan Sprent
    Sprent J, 1978, 'Restricted helper function of F1 hybrid T cell spositively selected to heterologous erythrocytes in irradiated parental strain mice: I. Failure to collaborate with b cells of the opposite parental strain not associated with active suppression*', Journal of Experimental Medicine, vol. 147, pp. 1142 - 1158, http://dx.doi.org/10.1084/jem.147.4.1142
    Journal articles | 1978
    Professor Jonathan Sprent
    Sprent J, 1978, 'Restricted helper function of F1 → parent bone mape row chimeras controlled by K-end of h-2 complex', Journal of Experimental Medicine, vol. 147, pp. 1838 - 1842, http://dx.doi.org/10.1084/jem.147.6.1838
    Journal articles | 1978
    Professor Jonathan Sprent
    Sprent J, 1978, 'Restricted helper function of F1 hybrid T cells positively selected to heterologous erythrocytes in irradiated parental strain mice: II. Evidence for restrictions affecting helper cell induction and T-B collaboration, both mapping to the K-end of the H-2 complex*', Journal of Experimental Medicine, vol. 147, pp. 1159 - 1174, http://dx.doi.org/10.1084/jem.147.4.1159
    Journal articles | 1978
    Professor Jonathan Sprent
    Sprent J, 1978, 'Role of the H-2 complex in induction of T helper cells in vivo: I. Antigen-specific selection of donor T cells to sheep erythrocytes in irradiated mice dependent upon sharing of H-2 determinants between donor and host*', Journal of Experimental Medicine, vol. 148, pp. 478 - 489, http://dx.doi.org/10.1084/jem.148.2.478
    Journal articles | 1978
    Professor Jonathan Sprent
    SPRENT J, 1978, 'Role of H‐2 Gene Products in the Function of T Helper Cells from Normal and Chimeric Mice in Vivo', Immunological Reviews, vol. 42, pp. 108 - 137, http://dx.doi.org/10.1111/j.1600-065X.1978.tb00260.x
    Journal articles | 1977
    Professor Jonathan Sprent
    Wilson DB; Lindahl KF; Wilson DH; Sprent J, 1977, 'The generation of killer cells to trinitrophenyl-modified allogeneic targets by lymphocyte populations negatively selected to strong alloantigens*', Journal of Experimental Medicine, vol. 146, pp. 361 - 367, http://dx.doi.org/10.1084/jem.146.2.361
    Journal articles | 1977
    Professor Jonathan Sprent
    von Boehmer H; Sprent J; Haas W, 1977, 'The influence of H-2 gene products on cell-mediated and humoral immune responses.', Cold Spring Harbor symposia on quantitative biology, vol. 41 Pt 2, pp. 539 - 545, http://dx.doi.org/10.1101/sqb.1977.041.01.062
    Journal articles | 1977
    Professor Jonathan Sprent
    Wilson DB; Heber-Katz E; Sprent J; Howard JC, 1977, 'On the possibility of multiple t-cell receptors.', Cold Spring Harbor symposia on quantitative biology, vol. 41 Pt 2, pp. 559 - 561, http://dx.doi.org/10.1101/sqb.1977.041.01.064
    Journal articles | 1976
    Professor Jonathan Sprent
    Hudson L; Sprent J, 1976, 'Specific adsorption of IgM antibody onto H-2-activated mouse T lymphocytes', Journal of Experimental Medicine, vol. 143, pp. 444 - 449, http://dx.doi.org/10.1084/jem.143.2.444
    Journal articles | 1976
    Professor Jonathan Sprent
    Sprent J; von Boehmer H, 1976, 'Activation of T lymphocytes to M locus determinants in vivo.. I. Quantitation of T cell proliferation and migration into thoracic duct lymph', European Journal of Immunology, vol. 6, pp. 352 - 358, http://dx.doi.org/10.1002/eji.1830060510
    Journal articles | 1976
    Professor Jonathan Sprent
    Von Boehmer H; Sprent J; Nabholz M, 1976, 'Hemopoietic reconstitution obtained in F1 hybrids by grafting of parental marrow cells', Transplantation Proceedings, vol. 8, pp. 355 - 358
    Journal articles | 1976
    Professor Jonathan Sprent
    Sprent J; Miller JFAP, 1976, 'Fate of H2-activated T lymphocytes in syngeneic hosts. III. Differentiation into long-lived recirculating memory cells', Cellular Immunology, vol. 21, pp. 314 - 326, http://dx.doi.org/10.1016/0008-8749(76)90059-9
    Journal articles | 1976
    Professor Jonathan Sprent
    Sprent J, 1976, 'Fate of H2-activated T lymphocytes in syngeneic hosts. I. Fate in lymphoid tissues and intestines traced with 3H-thymidine, 125I-deoxyuridine and 51chromium', Cellular Immunology, vol. 21, pp. 278 - 302, http://dx.doi.org/10.1016/0008-8749(76)90057-5
    Journal articles | 1976
    Professor Jonathan Sprent
    Sprent J; Miller JFAP, 1976, 'Fate of H2-activated T lymphocytes in syngeneic hosts. II. Residence in recirculating lymphocyte pool and capacity to migrate to allografts', Cellular Immunology, vol. 21, pp. 303 - 313, http://dx.doi.org/10.1016/0008-8749(76)90058-7
    Journal articles | 1976
    Professor Jonathan Sprent
    Sprent J; Von Boehmer H, 1976, 'Helper function of t cells depleted of alloantigen-reactive lymphocytes by filtration through irradiated f1 hybrid recipients: I. Failure to collaborate with allogeneic B cells in a secondary response to sheep erythrocytes measured in vivo', Journal of Experimental Medicine, vol. 144, pp. 617 - 626, http://dx.doi.org/10.1084/jem.144.3.617
    Journal articles | 1976
    Professor Jonathan Sprent
    Sprent J; Miller JFAP, 1976, 'Effect of recent antigen priming on adoptive immune responses: III. Antigen-induced selective recruitment of subsets of recirculating lymphocytes reactive to h-2 determinants', Journal of Experimental Medicine, vol. 143, pp. 585 - 600, http://dx.doi.org/10.1084/jem.143.3.585
    Journal articles | 1976
    Professor Jonathan Sprent
    Sprent J; Lefkovits I, 1976, 'Effect of recent antigen priming on adoptive immune responses', Journal of Experimental Medicine, vol. 143, pp. 1289 - 1298, http://dx.doi.org/10.1084/jem.143.6.1289
    Journal articles | 1976
    Professor Jonathan Sprent
    Von Boehmer H; Sprent J, 1976, 'T cell function in bone marrow chimeras: absence of host reactive T cells and cooperation of helper T cells across allogeneic barriers', TRANSPLANT.REV., vol. Vol. 29, pp. 3 - 23
    Journal articles | 1976
    Professor Jonathan Sprent
    Boehmer HV; Sprent J, 1976, 'T Cell Function in Bone Marrow Chimeras; Absence of Host‐Reactive T Cells and Cooperation of Helper T Cells across Allogeneic Barriers', Immunological Reviews, vol. 29, pp. 3 - 25, http://dx.doi.org/10.1111/j.1600-065X.1976.tb00195.x
    Journal articles | 1975
    Professor Jonathan Sprent
    Krammer PH; Hudson L; Sprent J, 1975, 'Fc receptors, Ia antigens, and immunoglobulin on normal and activated mouse T lymphocytes', Journal of Experimental Medicine, vol. 142, pp. 1403 - 1415, http://dx.doi.org/10.1084/jem.142.6.1403
    Journal articles | 1975
    Professor Jonathan Sprent
    Sprent J; Von Boehmer H; Nabholz M, 1975, 'Association of immunity and tolerance to host H 2 determinants in irradiated F1 hybrid mice reconstituted with bone marrow cells from one parental strain', Journal of Experimental Medicine, vol. 142, pp. 321 - 331, http://dx.doi.org/10.1084/jem.142.2.321
    Journal articles | 1975
    Professor Jonathan Sprent
    Von Boehmer H; Sprent J; Nabholz M, 1975, 'Tolerance to histocompatibility determinants in tetraparental bone marrow chimeras', Journal of Experimental Medicine, vol. 141, pp. 322 - 334, http://dx.doi.org/10.1084/jem.141.2.322
    Journal articles | 1975
    Professor Jonathan Sprent
    Melchers F; Cone RE; von Boehmer H; Sprent J, 1975, 'Immunoglobulin turnover in B lymphocyte subpopulations', European Journal of Immunology, vol. 5, pp. 382 - 388, http://dx.doi.org/10.1002/eji.1830050606
    Journal articles | 1975
    Professor Jonathan Sprent
    Roelants GE; Loor F; von Boehmer H; Sprent J; Hägg L; Mayor KS; Rydén A, 1975, 'Five types of lymphocytes (lg θ, lg θ+ weak, lg θ+strong, lg+ θ and lg+ θ+) characterized by double immunofluorescence and electrophoretic mobility Organ distribution in normal and nude mice', European Journal of Immunology, vol. 5, pp. 127 - 131, http://dx.doi.org/10.1002/eji.1830050211
    Journal articles | 1975
    Professor Jonathan Sprent
    Von Boehmer H; Hudson L; Sprent J, 1975, 'Collaboration of histoincompatible T and B lymphocytes using cells from tetraparental bone marrow chimeras', Journal of Experimental Medicine, vol. 142, pp. 987 - 997, http://dx.doi.org/10.1084/jem.142.4.989
    Journal articles | 1975
    Professor Jonathan Sprent
    Sprent J, 1975, 'Thoracic duct cannulation of mice', U.I.C.C. Technical Report Series, vol. Vol. 20, pp. 135 - 136
    Journal articles | 1974
    Professor Jonathan Sprent
    Hudson L; Sprent J; Miller JFAP; Playfair JHL, 1974, 'B cell-derived immunoglobulin on activated mouse T lymphocytes', Nature, vol. 251, pp. 60 - 62, http://dx.doi.org/10.1038/251060a0
    Journal articles | 1974
    Professor Jonathan Sprent
    Sprent J; Anderson RE; Miller JFAP, 1974, 'Radiosensitivity of T and B lymphocytes. II. Effect of irradiation on response of T cells to alloantigens', European Journal of Immunology, vol. 4, pp. 204 - 210, http://dx.doi.org/10.1002/eji.1830040310
    Journal articles | 1974
    Professor Jonathan Sprent
    Cheers C; Sprent J; Miller JFAP, 1974, 'Interaction of thymus lymphocytes with histoincompatible cells. IV. Mixed lymphocyte reactions of activated thymus lymphocytes', Cellular Immunology, vol. 10, pp. 57 - 67, http://dx.doi.org/10.1016/0008-8749(74)90151-8
    Journal articles | 1974
    Professor Jonathan Sprent
    Anderson RE; Sprent J; Miller JFAP, 1974, 'Radiosensitivity of T and B lymphocytes. I. Effect of irradiation on cell migration', European Journal of Immunology, vol. 4, pp. 199 - 203, http://dx.doi.org/10.1002/eji.1830040309
    Journal articles | 1974
    Professor Jonathan Sprent
    Von Boehmer H; Sprent J, 1974, 'Expression of M locus differences by B cells but not T cells', Nature, vol. 249, pp. 363 - 365, http://dx.doi.org/10.1038/249363a0
    Journal articles | 1974
    Professor Jonathan Sprent
    Pernis B; Miller JFAP; Forni L; Sprent J, 1974, 'Immunoglobulin on activated T cells detected by indirect immunofluorescence', Cellular Immunology, vol. 10, pp. 476 - 482, http://dx.doi.org/10.1016/0008-8749(74)90139-7
    Journal articles | 1974
    Professor Jonathan Sprent
    Sprent J; Miller JFAP, 1974, 'Effect of recent antigen priming on adoptive immune responses: II. Specific unresponsiveness of circulating lymphocytes from mice primed with heterologous erythrocytes', Journal of Experimental Medicine, vol. 139, pp. 1 - 12, http://dx.doi.org/10.1084/jem.139.1.1
    Journal articles | 1974
    Professor Jonathan Sprent
    Basten A; Miller JFAP; Sprent J; Cheers C, 1974, 'Cell-to-cell interaction in the immune response: X. t-cell-dependent suppression in tolerant mice', Journal of Experimental Medicine, vol. 140, pp. 199 - 217, http://dx.doi.org/10.1084/jem.140.1.199
    Journal articles | 1973
    Professor Jonathan Sprent
    Sprent J; Basten A, 1973, 'Circulating T and B lymphocytes of the mouse. II. Lifespan', Cellular Immunology, vol. 7, pp. 40 - 59, http://dx.doi.org/10.1016/0008-8749(73)90181-0
    Journal articles | 1973
    Professor Jonathan Sprent
    Sprent J, 1973, 'Circulating T and B lymphocytes of the mouse. I. Migratory properties', Cellular Immunology, vol. 7, pp. 10 - 39, http://dx.doi.org/10.1016/0008-8749(73)90180-9
    Journal articles | 1973
    Professor Jonathan Sprent
    Sprent J, 1973, 'The proliferation response of T lymphocytes to alloantigens in irradiated mice: a mixed lymphocyte reaction in vivo.', Transplantation Proceedings, vol. 5, pp. 1725 - 1729
    Journal articles | 1973
    Professor Jonathan Sprent
    Sprent J; Hudson L, 1973, 'Surface immunoglobulin on H-2-activated T lymphocytes.', Transplantation Proceedings, vol. 5, pp. 1731 - 1733
    Journal articles | 1973
    Professor Jonathan Sprent
    Cheers C; Sprent J, 1973, 'B lymphocytes as stimulators of a mixed lymphocyte reaction', Transplantation, vol. 15, pp. 336 - 337, http://dx.doi.org/10.1097/00007890-197303000-00014
    Journal articles | 1973
    Professor Jonathan Sprent
    Cheers C; Sprent J, 1973, 'Proliferation of activated thymocytes in mixed lymphocyte reactions.', Advances in experimental medicine and biology, vol. 29, pp. 149 - 156, http://dx.doi.org/10.1007/978-1-4615-9017-0_22
    Journal articles | 1973
    Professor Jonathan Sprent
    Sprent J; Miller JFAP, 1973, 'Effect of recent antigen priming on adoptive immune responses: I. Specific unresponsiveness of cells from lymphoid organs of mice primed with heterologous erythrocytes', Journal of Experimental Medicine, vol. 138, pp. 143 - 162, http://dx.doi.org/10.1084/jem.138.1.143
    Journal articles | 1972
    Professor Jonathan Sprent
    Cone RE; Sprent J; Marchalonis JJ, 1972, 'Antigen-binding specificity of isolated cell-surface immunoglobulin from thymus cells activated to histocompatibility antigens.', Proceedings of the National Academy of Sciences of the United States of America, vol. 69, pp. 2556 - 2560, http://dx.doi.org/10.1073/pnas.69.9.2556
    Journal articles | 1972
    Professor Jonathan Sprent
    Basten A; Sprent J; Miller JFAP, 1972, 'Receptor for antibody-antigen complexes used to separate T cells from B cells', Nature New Biology, vol. 235, pp. 178 - 180, http://dx.doi.org/10.1038/newbio235178a0
    Journal articles | 1972
    Professor Jonathan Sprent
    Sprent J; Miller JFAP, 1972, 'Interaction of thymus lymphocytes with histoincompatible cells. III. Immunological characteristics of recirculating lymphocytes derived from activated thymus cells', Cellular Immunology, vol. 3, pp. 213 - 230, http://dx.doi.org/10.1016/0008-8749(72)90161-X
    Journal articles | 1972
    Professor Jonathan Sprent
    Sprent J; Miller JFAP, 1972, 'Interaction of thymus lymphocytes with histoincompatible cells. I. Quantitation of the proliferative response of thymus cells', Cellular Immunology, vol. 3, pp. 361 - 384, http://dx.doi.org/10.1016/0008-8749(72)90244-4
    Journal articles | 1972
    Professor Jonathan Sprent
    Sprent J; Miller JFAP, 1972, 'Thoracic duct lymphocytes from nude mice: Migratory properties and life‐span', European Journal of Immunology, vol. 2, pp. 384 - 387, http://dx.doi.org/10.1002/eji.1830020420
    Journal articles | 1972
    Professor Jonathan Sprent
    Sprent J; Miller JFAP, 1972, 'Interaction of thymus lymphocytes with histoincompatible cells. II. Recirculating lymphocytes derived from antigen-activated thymus cells', Cellular Immunology, vol. 3, pp. 385 - 404, http://dx.doi.org/10.1016/0008-8749(72)90245-6
    Journal articles | 1972
    Professor Jonathan Sprent
    Basten A; Miller JFAP; Sprent J; Pye J, 1972, 'A receptor for antibody on b lymphocytes: I. method of detection and functional significance', Journal of Experimental Medicine, vol. 135, pp. 610 - 626, http://dx.doi.org/10.1084/jem.135.3.610
    Journal articles | 1972
    Professor Jonathan Sprent
    Cline MJ; Sprent J; Warner NL; Harris AW, 1972, 'Receptors for immunoglobulin on B lymphocytes and cells of a cultured plasma cell tumor.', Journal of Immunology, vol. 108, pp. 1126 - 1128
    Journal articles | 1972
    Professor Jonathan Sprent
    Anderson RE; Sprent J; Miller JFAP, 1972, 'Cell-to-cell interaction in the immune response: VIII. radiosensitivity of thymus-derived lymphocytes', Journal of Experimental Medicine, vol. 135, pp. 711 - 717, http://dx.doi.org/10.1084/jem.135.3.711
    Journal articles | 1972
    Professor Jonathan Sprent
    Nossal GJV; Warner NL; Lewis H; Sprent J, 1972, 'Quantitative features of a sandwich radioimmunolabeling technique for lymphocyte surface receptors', Journal of Experimental Medicine, vol. 135, pp. 405 - 428, http://dx.doi.org/10.1084/jem.135.2.405
    Journal articles | 1972
    Professor Jonathan Sprent
    Miller JFAP; Sprent J; Basten A; Warner NL, 1972, 'Selective cytotoxicity of anti-kappa serum for B lymphocytes', Nature New Biology, vol. 237, pp. 18 - 20, http://dx.doi.org/10.1038/newbio237018a0
    Journal articles | 1971
    Professor Jonathan Sprent
    Miller JFAP; Sprent J; Basten A; Warner NL; Breitner JCS; Rowland G; Hamilton J; Silver H; Martin WJ, 1971, 'Cell-to-cell interaction in the immune response: VII. Requirement for differentiation of thymus-derived cells', Journal of Experimental Medicine, vol. 134, pp. 1266 - 1284, http://dx.doi.org/10.1084/jem.134.5.1266
    Journal articles | 1971
    Professor Jonathan Sprent
    Sprent J; Miller JFAP; Mitchell GF, 1971, 'Antigen-induced selective recruitment of circulating lymphocytes', Cellular Immunology, vol. 2, pp. 171 - 181, http://dx.doi.org/10.1016/0008-8749(71)90036-0
    Journal articles | 1971
    Professor Jonathan Sprent
    Miller JFAP; Sprent J, 1971, 'Cell-to-cell interaction in the immune response: VI. Contribution of thymus-derived cells and antibody-forming cell precursors to immunological memory', Journal of Experimental Medicine, vol. 134, pp. 66 - 82, http://dx.doi.org/10.1084/jem.134.1.66
    Journal articles | 1971
    Professor Jonathan Sprent
    Miller JF; Brunner KT; Sprent J; Russell PJ; Mitchell GF, 1971, 'Thymus-derived cells as killer cells in cell-mediated immunity.', Transplantation Proceedings, vol. 3, pp. 915 - 917
    Journal articles | 1971
    Professor Jonathan Sprent
    Bankhurst AD; Warner NL; Sprent J, 1971, 'Surface immunoglobulins on thymus and thymus-derived lymphoid cells', Journal of Experimental Medicine, vol. 134, pp. 1005 - 1015, http://dx.doi.org/10.1084/jem.134.4.1005
    Journal articles | 1971
    Professor Jonathan Sprent
    Sprent J; Miller JFAP, 1971, 'Activation of thymus cells by histocompatibility antigens', Nature New Biology, vol. 234, pp. 195 - 198, http://dx.doi.org/10.1038/newbio234195a0
    Journal articles | 1971
    Professor Jonathan Sprent
    Miller JFAP; Sprent J, 1971, 'Thymus-derived cells in mouse thoracic duct lymph', Nature New Biology, vol. 230, pp. 267 - 271, http://dx.doi.org/10.1038/newbio230267a0
    Journal articles | 1971
    Professor Jonathan Sprent
    Miller JFAP; Basten A; Sprent J; Cheers C, 1971, 'Interaction between lymphocytes in immune responses', Cellular Immunology, vol. 2, pp. 469 - 495, http://dx.doi.org/10.1016/0008-8749(71)90057-8
  • Other | 2017
    Professor Jonathan Sprent
    Hedrick S; Sprent J, 2017, Charles D. Surh 1961-2017 Obituary, CELL PRESS, http://dx.doi.org/10.1016/j.immuni.2017.11.017
    Conference Abstracts | 2017
    Professor Jonathan Sprent
    Wiletel M; Mahr B; Granofszky N; Muckenhuber M; Wekerle T; Sprent J; Pilat N, 2017, 'MANIPULATION OF THE T CELL COMPARTMENT WITH IL2MAB COMPLEXES FOR TOLERANCE INDUCTION', in TRANSPLANT INTERNATIONAL, WILEY, Vol. 30, pp. 5 - 5, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000412907000002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2017
    Professor Jonathan Sprent
    Pilat N; Wiletel M; Mahr B; Granofszky N; Muckenhuber M; Wekerle T; Webster K; Sprent J, 2017, 'ANTI-IL6 SYNERGIZES WITH IL2CPLX TREATMENT TO PROMOTE TRANSPLANTATION TOLERANCE BY MECHANISMS INVOLVING TREGS AND APCS', in TRANSPLANT INTERNATIONAL, WILEY, pp. 11 - 12, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000412907000027&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2017
    Professor Jonathan Sprent
    Pilat N; Mahr B; Wiletel M; Granofszky N; Warren J; Corpuz T; Wekerle T; Webster K; Sprent J, 2017, 'COMBINATION OF IL2/ANTI-IL2 COMPLEXES AND ANTI-INFLAMMATORY THERAPY FOR TOLERANCE INDUCTION', in TRANSPLANT INTERNATIONAL, WILEY, Vol. 30, pp. 164 - 164, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000411688501206&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Professor Jonathan Sprent
    Jandl C; Liu SM; Nieto FDCP; Warren J; Hughes WE; Vogelzang A; Webster K; Craig M; Uzel G; Tangye S; Dent A; Vinuesa C; Sprent J; King C, 2016, 'Interleukin-21 limits regulatory T cell populations by modulating responsiveness to Interleukin-2', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 102 - 102, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400203&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Professor Jonathan Sprent
    Vazquez-Lombardi R; Webster KE; Sprent J; Christ D, 2016, 'Potent antitumor activity of IL-2-Fc fusion proteins through Fc gamma R-dependent depletion of CD4(+) CD25(+) Tregs', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 1209 - 1209, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402834&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Professor Jonathan Sprent
    Stolp J; Corpuz T; Pinget G; Sprent J; Webster K, 2016, 'Obesity triggers changes in skin IL-17-producing gamma delta T cells', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 257 - 258, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400520&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2008
    Professor Jonathan Sprent
    Loebbermann J; Lee DJ; Webster KN; Sprent J; Johansson C; Openshaw P, 2008, 'Contrasting effects of natural regulatory T cells at different sites during respiratory viral infection', in Immunology, WILEY-BLACKWELL PUBLISHING, INC, Glasgow, SCOTLAND, pp. 68 - 69, presented at Annual Congress of the British-Society-of-Immunology, Glasgow, SCOTLAND, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000262764800218&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2006
    Professor Jonathan Sprent
    Walters SN; Sutherland AP; Thaxton J; Groom JR; Liuwantara D; Marino E; Mackay F; Sprent J; Grey S, 2006, 'BAFF alters T-cell-dependant immune responses allowing allograft acceptance', in American Journal of Transplantation, Blackwell Munksgaard, Copenhagen, Denmark, pp. 205 - 205, presented at TSANZ - 24th Australian Academy of Science, Canberra, 29 March 2006 - 31 March 2006, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255763200096&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2001
    Professor Jonathan Sprent
    Sprent J; Kishimoto H, 2001, 'The thymus and central tolerance', in Transplantation
    Conference Papers | 2000
    Professor Jonathan Sprent
    Kishimoto H; Sprent J, 2000, 'The thymus and central tolerance', in Clinical Immunology, http://dx.doi.org/10.1006/clim.1999.4818
    Conference Papers | 1999
    Professor Jonathan Sprent
    Sprent J; Zhang X; Sun S; Tough D, 1999, 'T-cell turnover in vivo and the role of cytokines', in Immunology Letters, pp. 21 - 25, http://dx.doi.org/10.1016/S0165-2478(98)00119-9
    Conference Papers | 1999
    Professor Jonathan Sprent
    Sprent J, 1999, 'Presidential address to the American Association of Immunologists: Stimulating naive T cells', in Journal of Immunology, pp. 4629 - 4636
    Conference Papers | 1997
    Professor Jonathan Sprent
    Sprent J; Cai Z; Brunmark A; Jackson MR; Peterson PA, 1997, 'Constructing artificial antigen-presenting cells from drosophila cells', in Advances in Experimental Medicine and Biology, pp. 249 - 254, http://dx.doi.org/10.1007/978-1-4757-9966-8_41
    Conference Papers | 1996
    Professor Jonathan Sprent
    Cai Z; Brunmark A; Jackson MR; Loh D; Peterson PA; Sprent J, 1996, 'Transfected Drosophila cells as a probe for defining the minimal requirements for stimulating unprimed CD8+ T cells', in Proceedings of the National Academy of Sciences of the United States of America, pp. 14736 - 14741, http://dx.doi.org/10.1073/pnas.93.25.14736
    Conference Papers | 1996
    Professor Jonathan Sprent
    Sprent J, 1996, 'The thymus and central tolerance', in Hormone and Metabolic Research, pp. 294 - 295, http://dx.doi.org/10.1055/s-2007-979796
    Conference Papers | 1994
    Professor Jonathan Sprent
    Sprent J; Surh CD; Tough D, 1994, 'Fate of T and B cells transferred to SCID mice', in Research in Immunology, pp. 328 - 331, http://dx.doi.org/10.1016/S0923-2494(94)80194-0
    Conference Papers | 1993
    Professor Jonathan Sprent
    Heath WR; Miller JFAP; Sprent J, 1993, 'Protection against graft-versus-host disease by large doses of donor CD4+ T cells: A novel approach to bone marrow transplantation', in Transplantation Proceedings, pp. 1222 - 1224
    Conference Papers | 1992
    Professor Jonathan Sprent
    Sprent J; Kosaka H; Gao EK, 1992, 'T cell tolerance after bone marrow transplantation in mice', in Bone Marrow Transplantation, pp. 5 - 9
    Conference Papers | 1991
    Professor Jonathan Sprent
    Webb SR; Sprent J, 1991, 'Cells inducing tolerance to M1s and H-2 antigens', in Advances in Experimental Medicine and Biology, pp. 149 - 158
    Conference Papers | 1989
    Professor Jonathan Sprent
    Sprent J; Gao EK; Webb SR, 1989, 'T-cell tolerance to H-2 molecules: Role of the thymus', in Cold Spring Harbor Symposia on Quantitative Biology, pp. 789 - 797, http://dx.doi.org/10.1101/sqb.1989.054.01.092

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