Working with colleagues in Australia, Canada, Britain and the US, our studies aim to determine some of the ways that cells in arteries communicate with one another and specifically, at how cells control the balance between the way that arteries narrow (constrict) and enlarge (dilate). This balance is referred to as vascular tone and is the main determinant of blood pressure and thus cardiovascular disease. Coordination of vascular tone is dependent on signals passing through junctions within and between the cellular layers in arteries. Our studies correlate anatomy and function, to identify the fundamental pathways that underlie blood vessel function.
Broad Research Areas:
Physiology, Cardiology and Vascular Disease, Anatomy, Pharmacology, Neuroscience
BSc (Hons), PhD
Society Memberships & Professional Activities:
American Heart Association., Australian and New Zealand Microcirculation Society (ANZMS; President, 2008-2009)., Australian Physiological Society (AuPS)., Australian Society of Clinical and Experimental Pharmacology and Toxicology (ASCEPT), British Pharmacological Society (BPS)., National Association of Research Fellows (NARF)., , , Occasional referee for;, American Journal of Physiology: Heart and Circulatory Physiology; Autonomic Neuroscience: Basic and Clinical; Arteriosclerosis, Thrombosis and Vascular Biology; British Journal of Pharmacology; Clinical and Experimental Physiology and Pharmacology; Experimental Eye Research; Journal of Anatomy; Journal of Cellular Physiology; Journal of Hypertension; Journal of Pharmacology and Experimental Therapeutics; Journal of Physiology; Journal of Vascular Research; Microcirculation; Microvascular Research; Regulatory Peptides; Stroke., , National Heart Foundation of Australia, National Health and Medical Research Council of Australia, The Wellcome Trust.
Specific Research Keywords:
Vascular Biology, Endothelial Biology, Obesity, Cell Coupling, Electron Microscopy