Dr Sophie   Stocker
Conjoint Senior Lecturer

Dr Sophie Stocker

PhD, BSc (Hons I)

Medicine & Health
St Vincent's Clinical School

Sophie Stocker is a Senior Hospital Scientist in the Department of Clinical Pharmacology and Toxicology at St Vincent’s Hospital, Sydney. She is also a conjoint lecturer of the St Vincent’s Clinical School, University of New South Wales. Her research program involves clinical and experimental pharmacology, ethnopharmacology, pharmacogenomics, pharmacometrics and qualitative research on the impact of intrinsic and extrinsic factors on drug disposition, efficacy and safety. Her research focuses on understanding variability in response to medicines and how this can be managed to optimise patient care.

On the international front, Dr Sophie Stocker is a founding member of the inaugural Global Pharmacogenomics (PGx) Society, affiliated with the Pharmacogenomics Research Network (PGRN), and is on the Steering Committee for PGx implementation which aims to translate genetic research into routine clinical practice. She is a Co-Principal investigator for an international collaborative GWAS examining ‘The Genetic Determinates of Metformin Pharmacokinetics’. She is the International Association of Therapeutic Drug Monitoring and Clinical Toxicology Young Scientist Australian representative. 

Phone
02 83822617
Location
Department of Clinical Pharmacology & Toxicology St Vincent’s Hospital Sydney Therapeutics Centre, Level 2 Xavier Building 390 Victoria Street DARLINGHURST NSW 2010 St Vincent's Clinical School, UNSW Medicine, UNSW Sydney

Publications

  • Book Chapters | 2018
    Dr Sophie Stocker
    Baysari M; Chan J; Carland J; Stocker S; Moran M; Day R, 2018, 'Usability of Reports Generated by a Computerised Dose Prediction Software', in Connecting the System to Enhance the Practitioner and Consumer Experience in Healthcare, IOS Press, Netherlands, pp. 27 - 32, http://dx.doi.org/10.3233/978-1-61499-890-7-27
    Book Chapters | 2013
    Dr Sophie Stocker
    Stocker SL; Riedmaier AE; Schwab M; Giacomini KM, 2013, 'OCT (SLC22A) and OCTN Family', in Pharmacogenomics of Human Drug Transporters: Clinical Impacts, pp. 171 - 208, http://dx.doi.org/10.1002/9781118353240.ch8
  • Journal articles | 2021
    Dr Sophie Stocker
    Nathan N; Nguyen AD; Stocker S; Laba TL; Baysari MT; Day RO, 2021, 'Out-of-pocket spending among a cohort of Australians living with gout', International Journal of Rheumatic Diseases, vol. 24, pp. 327 - 334, http://dx.doi.org/10.1111/1756-185X.13979
    Journal articles | 2021
    Dr Sophie Stocker
    Carland JE; Elhage T; Baysari MT; Stocker SL; Marriott DJE; Taylor N; Day RO, 2021, 'Would they trust it? An exploration of psychosocial and environmental factors affecting prescriber acceptance of computerised dose-recommendation software', British Journal of Clinical Pharmacology, vol. 87, pp. 1215 - 1233, http://dx.doi.org/10.1111/bcp.14496
    Journal articles | 2021
    Dr Sophie Stocker
    Sandaradura I; Marriott DJE; Day RO; Norris RLG; Pang E; Stocker SL; Reuter SE, 2021, 'Current fluconazole treatment regimens result in under-dosing of critically ill adults during early therapy', European Journal of Clinical Microbiology and Infectious Diseases, http://dx.doi.org/10.1007/s10096-021-04201-w
    Journal articles | 2021
    Dr Sophie Stocker
    Stocker SL; Carland JE; Reuter SE; Stacy AE; Schaffer AL; Stefani M; Lau C; Kirubakaran R; Yang JJ; Shen CFJ; Roberts DM; Marriott DJE; Day RO; Brett J, 2021, 'Evaluation of a Pilot Vancomycin Precision Dosing Advisory Service on Target Exposure Attainment Using an Interrupted Time Series Analysis', Clinical Pharmacology and Therapeutics, vol. 109, pp. 212 - 221, http://dx.doi.org/10.1002/cpt.2113
    Journal articles | 2021
    Dr Sophie Stocker
    Uster DW; Stocker SL; Carland JE; Brett J; Marriott DJE; Day RO; Wicha SG, 2021, 'A Model Averaging/Selection Approach Improves the Predictive Performance of Model-Informed Precision Dosing: Vancomycin as a Case Study', Clinical Pharmacology and Therapeutics, vol. 109, pp. 175 - 183, http://dx.doi.org/10.1002/cpt.2065
    Journal articles | 2021
    Dr Sophie Stocker
    Carland JE; Stocker SL; Baysari MT; Li C; Själin J; Moran MA; Tang S; Sandaradura I; Elhage T; Gilbey T; Williams KM; Marriott DJE; Day RO, 2021, 'Are vancomycin dosing guidelines followed? A mixed methods study of vancomycin prescribing practices', British Journal of Clinical Pharmacology, http://dx.doi.org/10.1111/bcp.14834
    Journal articles | 2021
    Dr Sophie Stocker
    Sandaradura I; Wojciechowski J; Marriott DJE; Day RO; Stocker S; Reuter SE, 2021, 'Model-optimized fluconazole dose selection for critically ill patients improves early pharmacodynamic target attainment without the need for therapeutic drug monitoring', Antimicrobial Agents and Chemotherapy, vol. 65, http://dx.doi.org/10.1128/AAC.02019-20
    Journal articles | 2021
    Dr Sophie Stocker
    Coleshill MJ; Aung E; Carland JE; Faasse K; Stocker S; Day RO, 2021, 'Rebranding Gout: Could a Name Change for Gout Improve Adherence to Urate-Lowering Therapy?', Therapeutic Innovation and Regulatory Science, vol. 55, pp. 138 - 141, http://dx.doi.org/10.1007/s43441-020-00198-0
    Journal articles | 2021
    Dr Sophie Stocker
    Menz BD; Stocker SL; Verougstraete N; Kocic D; Galettis P; Stove CP; Reuter SE, 2021, 'Barriers and opportunities for the clinical implementation of therapeutic drug monitoring in oncology', British Journal of Clinical Pharmacology, vol. 87, pp. 227 - 236, http://dx.doi.org/10.1111/bcp.14372
    Journal articles | 2021
    Dr Sophie Stocker
    Roydhouse SA; Carland JE; Debono DS; Baysari MT; Reuter SE; Staciwa AJ; Sandhu APK; Day RO; Stocker SL, 2021, 'Accuracy of documented administration times for intravenous antimicrobial drugs and impact on dosing decisions', British Journal of Clinical Pharmacology, http://dx.doi.org/10.1111/bcp.14844
    Journal articles | 2021
    Dr Sophie Stocker
    Cunio CB; Uster DW; Carland JE; Buscher H; Liu Z; Brett J; Stefani M; Jones GRD; Day RO; Wicha SG; Stocker SL, 2021, 'Towards precision dosing of vancomycin in critically ill patients: an evaluation of the predictive performance of pharmacometric models in ICU patients', Clinical Microbiology and Infection, vol. 27, pp. 783.e7 - 783.e14, http://dx.doi.org/10.1016/j.cmi.2020.07.005
    Journal articles | 2021
    Dr Sophie Stocker
    Ryan AC; Carland JE; McLeay RC; Lau C; Marriott DJE; Day RO; Stocker SL, 2021, 'Evaluation of amikacin use and comparison of the models implemented in two Bayesian forecasting software packages to guide dosing', British Journal of Clinical Pharmacology, vol. 87, pp. 1422 - 1431, http://dx.doi.org/10.1111/bcp.14542
    Journal articles | 2020
    Dr Sophie Stocker
    Coulshed A; Nguyen AD; Stocker SL; Day RO, 2020, 'Australian patient perspectives on the impact of gout', International Journal of Rheumatic Diseases, vol. 23, pp. 1372 - 1378, http://dx.doi.org/10.1111/1756-185X.13934
    Journal articles | 2020
    Dr Sophie Stocker
    Day R; Nguyen A; Graham G; Aung E; Coleshill M; Stocker S, 2020, 'Better outcomes for patients with gout', Inflammopharmacology, vol. 28, pp. 1395 - 1400, http://dx.doi.org/10.1007/s10787-020-00694-7
    Journal articles | 2020
    Dr Sophie Stocker
    Day RO; Coleshill MJ; Stocker SL; Nguyen AD; Robinson P; Aung E, 2020, 'Predictors of success in gout treatment', Journal of Rheumatology, vol. 47, pp. 313 - 315, http://dx.doi.org/10.3899/jrheum.191150
    Journal articles | 2020
    Dr Sophie Stocker
    Xu A; Baysari MT; Stocker SL; Leow LJ; Day RO; Carland JE, 2020, 'Researchers' views on, and experiences with, the requirement to obtain informed consent in research involving human participants: A qualitative study', BMC Medical Ethics, vol. 21, pp. 93, http://dx.doi.org/10.1186/s12910-020-00538-7
    Journal articles | 2020
    Dr Sophie Stocker
    Shingde RV; Reuter SE; Graham GG; Carland JE; Williams KM; Day RO; Stocker SL, 2020, 'Assessing the accuracy of two bayesian forecasting programs in estimating vancomycin drug exposure', Journal of Antimicrobial Chemotherapy, vol. 75, pp. 3293 - 3302, http://dx.doi.org/10.1093/jac/dkaa320
    Journal articles | 2020
    Dr Sophie Stocker
    Milder TY; Day RO; Stocker SL; Greenfield JR, 2020, 'Should the cardio-protective properties of sodium-glucose cotransporter 2 inhibitors dictate therapeutic decision-making in patients with type 2 diabetes', Internal Medicine Journal, vol. 50, pp. 645 - 646, http://dx.doi.org/10.1111/imj.14819
    Journal articles | 2020
    Dr Sophie Stocker
    Kamel B; Graham GG; Stocker SL; Liu Z; Williams KM; Carland JE; Pile KD; Day RO, 2020, 'A pharmacokinetic-pharmacodynamic study of a single dose of febuxostat in healthy subjects', British Journal of Clinical Pharmacology, vol. 86, pp. 2486 - 2496, http://dx.doi.org/10.1111/bcp.14357
    Journal articles | 2020
    Dr Sophie Stocker
    Van Dort BA; Baysari MT; Carland JE; Stocker SL; Braithwaite HE; Fernon AR; Day RO, 2020, 'Education to improve vancomycin use: the perspectives of educators and education recipients', Internal Medicine Journal, vol. 50, pp. 565 - 572, http://dx.doi.org/10.1111/imj.14408
    Journal articles | 2020
    Dr Sophie Stocker
    Smith FC; Stocker SL; Danta M; Carland JE; Kumar SS; Liu Z; Greenfield JR; Braithwaite HE; Cheng TS; Graham GG; Williams KM; Day RO, 2020, 'The safety and pharmacokinetics of metformin in patients with chronic liver disease', Alimentary Pharmacology and Therapeutics, vol. 51, pp. 565 - 575, http://dx.doi.org/10.1111/apt.15635
    Journal articles | 2020
    Dr Sophie Stocker
    Kirubakaran R; Stocker SL; Hennig S; Day RO; Carland JE, 2020, 'Population Pharmacokinetic Models of Tacrolimus in Adult Transplant Recipients: A Systematic Review', Clinical Pharmacokinetics, vol. 59, pp. 1357 - 1392, http://dx.doi.org/10.1007/s40262-020-00922-x
    Journal articles | 2020
    Dr Sophie Stocker
    Milder TY; Stocker SL; Day RO; Greenfield JR, 2020, 'Potential Safety Issues with Use of Sodium-Glucose Cotransporter 2 Inhibitors, Particularly in People with Type 2 Diabetes and Chronic Kidney Disease', Drug Safety, vol. 43, pp. 1211 - 1221, http://dx.doi.org/10.1007/s40264-020-01010-6
    Journal articles | 2020
    Dr Sophie Stocker
    Chaudhri K; Stocker SL; Williams KM; McLeay RC; Marriott DJE; Di Tanna GL; Day RO; Carland JE, 2020, 'Voriconazole: An audit of hospital-based dosing and monitoring and evaluation of the predictive performance of a dose-prediction software package', Journal of Antimicrobial Chemotherapy, vol. 75, pp. 1981 - 1984, http://dx.doi.org/10.1093/jac/dkaa098
    Journal articles | 2019
    Dr Sophie Stocker
    Coleshill MJ; Aung E; Nguyen AD; Stocker SL; Baysari MT; Kamel B; Schulz M; McLachlan AJ; Day RO, 2019, 'Improving adherence to urate-lowering therapy in people living with gout', International Journal of Rheumatic Diseases, vol. 22, pp. 542 - 544, http://dx.doi.org/10.1111/1756-185X.13566
    Journal articles | 2019
    Dr Sophie Stocker
    Kamel B; Williams KM; Graham GG; Norris RLG; Stocker SL; Carland JE; Pile KD; Day RO, 2019, 'Determination of febuxostat in human plasma by high performance liquid chromatography (HPLC) with fluorescence-detection', Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, vol. 1126-1127, http://dx.doi.org/10.1016/j.jchromb.2019.121764
    Journal articles | 2019
    Dr Sophie Stocker
    Abdel Shaheed C; Carland JE; Graham GG; Stocker SL; Smith G; Hicks M; Williams KM; Furlong T; Macdonald P; Greenfield JR; Smith FC; Chowdhury G; Day RO, 2019, 'Is the use of metformin in patients undergoing dialysis hazardous for life? A systematic review of the safety of metformin in patients undergoing dialysis', British Journal of Clinical Pharmacology, vol. 85, pp. 2772 - 2783, http://dx.doi.org/10.1111/bcp.14107
    Journal articles | 2019
    Dr Sophie Stocker
    Broeker A; Nardecchia M; Klinker KP; Derendorf H; Day RO; Marriott DJ; Carland JE; Stocker SL; Wicha SG, 2019, 'Towards precision dosing of vancomycin: a systematic evaluation of pharmacometric models for Bayesian forecasting', Clinical Microbiology and Infection, vol. 25, pp. 1286.e1 - 1286.e7, http://dx.doi.org/10.1016/j.cmi.2019.02.029
    Journal articles | 2019
    Dr Sophie Stocker
    Day RO; Lau W; Stocker SL; Aung E; Coleshill MJ; Schulz M; Bechara J; Carland JE; Graham GG; Williams KM; McLachlan AJ, 2019, 'Management of gout in older people', Journal of Pharmacy Practice and Research, vol. 49, pp. 90 - 97, http://dx.doi.org/10.1002/jppr.1511
    Journal articles | 2019
    Dr Sophie Stocker
    Shingde RV; Graham GG; Reuter SE; Carland JE; Day RO; Stocker SL, 2019, 'Comparison of the Area under the Curve for Vancomycin Estimated Using Compartmental and Noncompartmental Methods in Adult Patients with Normal Renal Function', Therapeutic Drug Monitoring, vol. 41, pp. 726 - 731, http://dx.doi.org/10.1097/FTD.0000000000000690
    Journal articles | 2019
    Dr Sophie Stocker
    Milder TY; Stocker SL; Samocha-Bonet D; Day RO; Greenfield JR, 2019, 'Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes—cardiovascular and renal benefits in patients with chronic kidney disease', European Journal of Clinical Pharmacology, vol. 75, pp. 1481 - 1490, http://dx.doi.org/10.1007/s00228-019-02732-y
    Journal articles | 2019
    Dr Sophie Stocker
    Milder TY; Stocker SL; Shaheed CA; McGrath-Cadell L; Samocha-Bonet D; Greenfield JR; Day RO, 2019, 'Combination Therapy with an SGLT2 Inhibitor as Initial Treatment for Type 2 Diabetes: A Systematic Review and Meta-Analysis', JOURNAL OF CLINICAL MEDICINE, vol. 8, http://dx.doi.org/10.3390/jcm8010045
    Journal articles | 2018
    Dr Sophie Stocker
    Zamek-Gliszczynski MJ; Taub ME; Chothe PP; Chu X; Giacomini KM; Kim RB; Ray AS; Stocker SL; Unadkat JD; Wittwer MB; Xia C; Yee SW; Zhang L; Zhang Y, 2018, 'Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance', Clinical Pharmacology and Therapeutics, vol. 104, pp. 890 - 899, http://dx.doi.org/10.1002/cpt.1112
    Journal articles | 2018
    Dr Sophie Stocker
    Lea-Henry TN; Carland JE; Stocker SL; Sevastos J; Roberts DM, 2018, 'Clinical pharmacokinetics in kidney disease: Fundamental principles', Clinical Journal of the American Society of Nephrology, vol. 13, pp. 1085 - 1095, http://dx.doi.org/10.2215/CJN.00340118
    Journal articles | 2018
    Dr Sophie Stocker
    Roberts DM; Sevastos J; Carland JE; Stocker SL; Lea-Henry TN, 2018, 'Clinical pharmacokinetics in kidney disease application to rational design of dosing regimens', Clinical Journal of the American Society of Nephrology, vol. 13, pp. 1254 - 1263, http://dx.doi.org/10.2215/CJN.05150418
    Journal articles | 2018
    Dr Sophie Stocker
    Graham GG; Stocker SL; Kannangara DRW; Day RO, 2018, 'Predicting Response or Non-response to Urate-Lowering Therapy in Patients with Gout', Current Rheumatology Reports, vol. 20, http://dx.doi.org/10.1007/s11926-018-0760-2
    Journal articles | 2018
    Dr Sophie Stocker
    Day R; Kamel B; Graham GG; Williams KM; Stocker SL; Carland JE; Pile KD; Mcguigan LE; Portek IJ; Mcgill NW, 2018, 'A Multicentre Open-Label Pharmacokinetic-Pharmacodynamic Study of Febuxostat in Patients with Chronic Gout', Proceedings for Annual Meeting of The Japanese Pharmacological Society, vol. WCP2018, http://dx.doi.org/10.1254/jpssuppl.wcp2018.0_po1-11-12
    Journal articles | 2017
    Dr Sophie Stocker
    Hovelson DH; Xue Z; Zawistowski M; Ehm MG; Harris EC; Stocker SL; Gross AS; Jang I-J; Ieiri I; Lee J-E; Cardon LR; Chissoe SL; Abecasis G; Nelson MR, 2017, 'Characterization of ADME gene variation in 21 populations by exome sequencing', Pharmacogenetics and Genomics, vol. 27, pp. 89 - 100, http://dx.doi.org/10.1097/FPC.0000000000000260
    Journal articles | 2017
    Dr Sophie Stocker
    Day RO; Kannangara DRW; Stocker SL; Carland JE; Williams KM; Graham GG, 2017, 'Allopurinol: insights from studies of dose–response relationships', Expert Opinion on Drug Metabolism and Toxicology, vol. 13, pp. 449 - 462, http://dx.doi.org/10.1080/17425255.2017.1269745
    Journal articles | 2017
    Dr Sophie Stocker
    Kannangara DRW; Graham GG; Wright DFB; Stocker SL; Portek I; Pile KD; Barclay ML; Williams KM; Stamp LK; Day RO, 2017, 'Individualising the dose of allopurinol in patients with gout', British Journal of Clinical Pharmacology, vol. 83, pp. 2015 - 2026, http://dx.doi.org/10.1111/bcp.13307
    Journal articles | 2016
    Dr Sophie Stocker
    Morrissey KM; Stocker SL; Chen EC; Castro RA; Brett CM; Giacomini KM, 2016, 'The Effect of Nizatidine, a MATE2K Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin in Healthy Volunteers', Clinical Pharmacokinetics, vol. 55, pp. 495 - 506, http://dx.doi.org/10.1007/s40262-015-0332-9
    Journal articles | 2016
    Dr Sophie Stocker
    Rotroff DM; Oki NO; Liang X; Yee SW; Stocker SL; Corum DG; Meisner M; Fiehn O; Motsinger-Reif AA; Giacomini KM; Kaddurah-Daouk R, 2016, 'Pharmacometabolomic assessment of metformin in non-diabetic, African Americans', Frontiers in Pharmacology, vol. 7, http://dx.doi.org/10.3389/fphar.2016.00135
    Journal articles | 2016
    Dr Sophie Stocker
    Hibma JE; Zur AA; Castro RA; Wittwer MB; Keizer RJ; Yee SW; Goswami S; Stocker SL; Zhang X; Huang Y; Brett CM; Savic RM; Giacomini KM, 2016, 'The Effect of Famotidine, a MATE1-Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin', Clinical Pharmacokinetics, vol. 55, pp. 711 - 721, http://dx.doi.org/10.1007/s40262-015-0346-3
    Journal articles | 2016
    Dr Sophie Stocker
    Smith FC; Kumar SS; Furlong TJ; Gangaram SV; Greenfield JR; Stocker SL; Graham GG; Williams KM; Day RO, 2016, 'Pharmacokinetics of Metformin in Patients Receiving Regular Hemodiafiltration', American Journal of Kidney Diseases, vol. 68, pp. 990 - 992, http://dx.doi.org/10.1053/j.ajkd.2016.08.017
    Journal articles | 2015
    Dr Sophie Stocker
    Chen EC; Liang X; Yee SW; Geier EG; Stocker SL; Chen L; Giacomini KM, 2015, 'Targeted disruption of organic cation transporter 3 attenuates the pharmacologic response to metformin', Molecular Pharmacology, vol. 88, pp. 75 - 83, http://dx.doi.org/10.1124/mol.114.096776
    Journal articles | 2015
    Dr Sophie Stocker
    Chung WH; Chang WC; Stocker SL; Juo CG; Graham GG; Lee MHH; Williams KM; Tian YC; Juan KC; Wu YJJ; Yang CH; Chang CJ; Lin YJ; Day RO; Hung SI, 2015, 'Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: The impact of renal insufficiency, high plasma levels of oxypurinol and granulysin', Annals of the Rheumatic Diseases, vol. 74, pp. 2157 - 2164, http://dx.doi.org/10.1136/annrheumdis-2014-205577
    Journal articles | 2014
    Dr Sophie Stocker
    Goswami S; Yee SW; Stocker S; Mosley JD; Kubo M; Castro R; Mefford JA; Wen C; Liang X; Witte J; Brett C; Maeda S; Simpson MD; Hedderson MM; Davis RL; Roden DM; Giacomini KM; Savic RM, 2014, 'Erratum: Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin (Clinical Pharmacology and Therapeutics (2014) 96:3 (370-379) DOI:10.1038/clpt.2014.109)', Clinical Pharmacology and Therapeutics, vol. 96, pp. 626, http://dx.doi.org/10.1038/clpt.2014.109
    Journal articles | 2014
    Dr Sophie Stocker
    Goswami S; Yee SW; Stocker S; Mosley JD; Kubo M; Castro R; Mefford JA; Wen C; Liang X; Witte J; Brett C; Maeda S; Simpson MD; Hedderson MM; Davis RL; Roden DM; Giacomini KM; Savic RM, 2014, 'Genetic Variants in Transcription Factors Are Associated With the Pharmacokinetics and Pharmacodynamics of Metformin (vol 96, pg 370, 2014)', CLINICAL PHARMACOLOGY & THERAPEUTICS, vol. 96, pp. 626 - 626, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000343632900026&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2013
    Dr Sophie Stocker
    Dahlin A; Geier E; Stocker SL; Cropp CD; Grigorenko E; Bloomer M; Siegenthaler J; Xu L; Basile AS; Tang-Liu DDS; Giacomini KM, 2013, 'Gene expression profiling of transporters in the solute carrier and ATP-binding cassette superfamilies in human eye substructures', Molecular Pharmaceutics, vol. 10, pp. 650 - 663, http://dx.doi.org/10.1021/mp300429e
    Journal articles | 2013
    Dr Sophie Stocker
    Stocker SL; Morrissey KM; Yee SW; Castro RA; Xu L; Dahlin A; Ramirez AH; Roden DM; Wilke RA; McCarty CA; Davis RL; Brett CM; Giacomini KM, 2013, 'The effect of novel promoter variants in MATE1 and MATE2 on the pharmacokinetics and pharmacodynamics of metformin', Clinical Pharmacology and Therapeutics, vol. 93, pp. 186 - 194, http://dx.doi.org/10.1038/clpt.2012.210
    Journal articles | 2013
    Dr Sophie Stocker
    Morrissey KM; Stocker SL; Wittwer MB; Xu L; Giacomini KM, 2013, 'Renal transporters in drug development', Annual Review of Pharmacology and Toxicology, vol. 53, pp. 503 - 529, http://dx.doi.org/10.1146/annurev-pharmtox-011112-140317
    Journal articles | 2013
    Dr Sophie Stocker
    Yee SW; Nguyen AN; Brown C; Savic RM; Zhang Y; Castro RA; Cropp CD; Choi JH; Singh D; Tahara H; Stocker SL; Huang Y; Brett CM; Giacomini KM, 2013, 'Reduced renal clearance of cefotaxime in asians with a low-frequency polymorphism of OAT3 (SLC22A8)', Journal of Pharmaceutical Sciences, vol. 102, pp. 3451 - 3457, http://dx.doi.org/10.1002/jps.23581
    Journal articles | 2012
    Dr Sophie Stocker
    Stocker S; Mclachlan AJ; Savic RM; Kirkpatrick CM; Graham GG; Williams KM; Day RO, 2012, 'The pharmacokinetics of oxypurinol in people with gout', British Journal of Clinical Pharacology, vol. 74, pp. 477 - 489, http://dx.doi.org/10.1111/j.1365-2125.2012.04207.x
    Journal articles | 2012
    Dr Sophie Stocker
    Lee M-H; Stocker S; Anderson JM; Phillips EJ; Nolan DL; Williams KM; Graham GG; Sullivan JR; Day RO, 2012, 'Initiating allopurinol therapy: Do we need to know the patient's human leucocyte antigen status?', Internal Medicine Journal, vol. 42, pp. 411 - 416, http://dx.doi.org/10.1111/j.1445-5994.2011.02567.x
    Journal articles | 2011
    Dr Sophie Stocker
    Stocker SL; Graham GG; McLachlan AJ; Williams K; Day RO, 2011, 'Pharmacokinetic and Pharmacodynamic interaction between allopurinol and probenecid in patients with gout', Journal of Rheumatology, vol. 38, pp. 904 - 910, http://dx.doi.org/10.3899/jrheum.101160
    Journal articles | 2011
    Dr Sophie Stocker
    Ng DY; Stocker SL; Graham GG; Williams KM; Day RO, 2011, 'Lack of effect of hydrochlorothiazide and low-dose aspirin on the renal clearance of urate and oxypurinol after a single dose of allopurinol in normal volunteers', European Journal of Clinical Pharmacology, vol. 67, pp. 709 - 713, http://dx.doi.org/10.1007/s00228-010-0963-6
    Journal articles | 2011
    Dr Sophie Stocker
    Kannangara D; Datta I; Indraratna P; Stocker S; Portek I; Graham G; Williams K; Day R, 2011, 'INDIVIDUALISING ALLOPURINOL THERAPY IN GOUT', INTERNAL MEDICINE JOURNAL, vol. 41, pp. 30 - 30, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000290489900103&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2011
    Dr Sophie Stocker
    Ramasamy S; Kannangara D; Indraratna P; Stocker S; Jones G; Graham G; Williams K; Day R, 2011, 'ESTABLISHING THE USEFULNESS OF A SPOT URINE COLLECTION IN CALCULATING THE FRACTIONAL RENAL CLEARANCE OF URATE (FCU)', INTERNAL MEDICINE JOURNAL, vol. 41, pp. 31 - 31, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000290489900106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2010
    Dr Sophie Stocker
    Indraratna P; Stocker SL; Williams KM; Graham GG; Jones G; Day RO, 2010, 'A proposal for identifying the low renal uric acid clearance phenotype', Arthritis Research and Therapy, vol. 12, pp. 149 - 151, http://dx.doi.org/10.1186/ar3191
    Journal articles | 2010
    Dr Sophie Stocker
    Stocker S; Franklin M; Anderson JM; Pillans PI; Williams K; McLachlan AJ; Day RO; taylor P, 2010, 'Measurement of urinary oxypurinol by high performance liquid chromatography-tandem mass spectrometry', Journal of Chromatography, vol. 878, pp. 2363 - 2368, http://dx.doi.org/10.1016/j.jchromb.2010.07.017
    Journal articles | 2008
    Dr Sophie Stocker
    Chung Y; Stocker S; Graham GG; Day RO, 2008, 'Optimizing therapy with allopurinol: Factors limiting hypouricemic efficacy', American Journal of the Medical Sciences, vol. 335, pp. 219 - 226, http://dx.doi.org/10.1097/MAJ.0b013e31815acb10
    Journal articles | 2008
    Dr Sophie Stocker
    Stocker S; Williams KM; Mclachlan AJ; Graham GG; Day RO, 2008, 'Pharmacokinetic and pharmacodynamic interaction between allopurinol and probenecid in healthy subjects', Clinical Pharmacokinetics, vol. 47, pp. 111 - 118, http://dx.doi.org/10.2165/00003088-200847020-00004
    Journal articles | 2007
    Dr Sophie Stocker
    Day RO; Graham GG; Hicks M; Mclachlan AJ; Stocker S; Williams KM, 2007, 'Clinical pharmacokinetics and pharmacodynamics of allopurinol and oxypurinol', Clinical Pharmacokinetics, vol. 46, pp. 623 - 644, http://dx.doi.org/10.2165/00003088-200746080-00001
  • Reports | 2017
    Dr Sophie Stocker
    Kumar SS; Graham GG; Smith FC; Furlong TJ; Greenfield JR; Stocker SS; Carland JE; Day RO, 2017, Could metformin be used in patients with advanced chronic kidney disease?, http://dx.doi.org/10.1111/dom.12806
  • Conference Papers | 2020
    Dr Sophie Stocker
    Aung E; Coleshill M; Schulz M; Kamel B; Stocker S; Day R, 2020, 'RECRUITING PEOPLE WITH GOUT INTO A CLINICAL TRIAL IN PRIMARY CARE: THE GAPP EXPERIENCE', in INTERNAL MEDICINE JOURNAL, WILEY, pp. 42 - 42, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000553988700116&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Dr Sophie Stocker
    Green EAE; Yee SW; Rashkin SR; Witte J; Shin JG; Klovins J; Stocker S; Day R; Giacomini KM, 2019, 'GENETIC DETERMINANTS OF METFORMIN PHARM-ACOKINETICS: A METFORMIN GENETIC CONSORTIUM COLLABORATION.', in CLINICAL PHARMACOLOGY & THERAPEUTICS, WILEY, Washington, DC, Vol. 105, pp. S36 - S36, presented at Annual Meeting of the American-Society-for-Clinical-Pharmacology-and-Therapeutics, Washington, DC, 13 March 2019 - 16 March 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000458561100109&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Dr Sophie Stocker
    Shingde R; Graham G; Reuter S; Carland J; Williams K; Day R; Stocker S, 2019, 'PREDICTIVE PERFORMANCE OF A COMMERCIAL BAYESIAN FORECASTING PROGRAM IN ESTIMATING VANCOMYCIN DRUG EXPOSURE.', in CLINICAL PHARMACOLOGY & THERAPEUTICS, WILEY, Washington, DC, Vol. 105, pp. S38 - S38, presented at Annual Meeting of the American-Society-for-Clinical-Pharmacology-and-Therapeutics, Washington, DC, 13 March 2019 - 16 March 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000458561100115&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Dr Sophie Stocker
    Stocker SL; Carland JE; Moran MA; Tang S; Li CY; Alin JS; Gilbey T; Graham GG; Williams KM; Marriott DJ; Day RO, 2018, 'A CLINICAL EVALUATION OF VANCOMYCIN DOSING AND MONITORING.', in CLINICAL PHARMACOLOGY & THERAPEUTICS, WILEY, Orlando, FL, Vol. 103, pp. S88 - S88, presented at 119th Annual Meeting of the American-Society-for-Clinical-Pharmacology-and-Therapeutics (ASCPT) - Breaking Down Barriers to Effective Patient Care, Orlando, FL, 21 March 2018 - 24 March 2018, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000424997100316&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Other | 2017
    Dr Sophie Stocker
    Conference Abstracts | 2017
    Dr Sophie Stocker
    Kamel B; Stocker S; Graham G; Carland J; Parker M; Williams K; Pile K; Portek I; McGill N; Day R, 2017, 'A MULTICENTRE OPEN-LABEL PHARMACOKINETIC-PHARMACODYNAMIC (PKPD) STUDY OF FEBUXOSTAT IN PATIENTS WITH CHRONIC GOUT', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 47, pp. 14 - 14, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000400304400034&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2014
    Dr Sophie Stocker
    Goswami S; Yee S; Stocker SL; Mosley JD; Kubo M; Maeda S; Simpson MD; Davis RL; Roden DM; Savic R; Giacomini KM, 2014, 'GENETIC VARIANTS IN TRANSCRIPTION FACTORS ARE LINKED TO THE PHARMACOKINETICS AND PHARMACODYNAMICS OF METFORMIN', in CLINICAL PHARMACOLOGY & THERAPEUTICS, NATURE PUBLISHING GROUP, Atlanta, GA, pp. S57 - S58, presented at Annual Meeting of the American-Society-for-Clinical-Pharmacology-and-Therapeutics (ASCPT), Atlanta, GA, 18 March 2014 - 22 March 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000332009800170&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2014
    Dr Sophie Stocker
    Hibma JE; Zur AA; Wittwer MB; Castro RA; Stocker SL; Morrissey KM; Goswami S; Yee S; Savic RM; Brett CM; Giacomini KM, 2014, 'CLINICAL VALIDATION OF A SELECTIVE INHIBITOR OF MULTIDRUG AND TOXIN EXTRUSION PROTEIN, MATE1 (SLC47A1) IN HEALTHY VOLUNTEERS', in CLINICAL PHARMACOLOGY & THERAPEUTICS, NATURE PUBLISHING GROUP, Atlanta, GA, pp. S9 - S9, presented at Annual Meeting of the American-Society-for-Clinical-Pharmacology-and-Therapeutics (ASCPT), Atlanta, GA, 18 March 2014 - 22 March 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000332009800024&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2014
    Dr Sophie Stocker
    Goswami S; Yee S; Stocker SL; Mosley JD; Kubo M; Maeda S; Simpson MD; Davis RL; Roden DM; Savic R; Giacomini KM, 2014, 'GENETIC VARIANTS IN TRANSCRIPTION FACTORS ARE LINKED TO THE PHARMACOKINETICS AND PHARMACODYNAMICS OF METFORMIN', in CLINICAL PHARMACOLOGY & THERAPEUTICS, NATURE PUBLISHING GROUP, Atlanta, GA, pp. S10 - S11, presented at Annual Meeting of the American-Society-for-Clinical-Pharmacology-and-Therapeutics (ASCPT), Atlanta, GA, 18 March 2014 - 22 March 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000332009800029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2014
    Dr Sophie Stocker
    Hibma JE; Zur AA; Wittwer MB; Castro RA; Stocker SL; Morrissey KM; Goswami S; Yee S; Savic RM; Brett CM; Giacomini KM, 2014, 'CLINICAL VALIDATION OF A SELECTIVE INHIBITOR OF MULTIDRUG AND TOXIN EXTRUSION PROTEIN, MATE1 (SLC47A1) IN HEALTHY VOLUNTEERS', in CLINICAL PHARMACOLOGY & THERAPEUTICS, NATURE PUBLISHING GROUP, Atlanta, GA, pp. S57 - S57, presented at Annual Meeting of the American-Society-for-Clinical-Pharmacology-and-Therapeutics (ASCPT), Atlanta, GA, 18 March 2014 - 22 March 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000332009800169&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Dr Sophie Stocker
    Morrissey KM; Stocker SL; Castro RA; Brett CM; Giacomini KM, 2013, 'INVESTIGATION OF THE CLINICAL IMPACT OF NIZATIDINE, A SPECIFIC AND POTENT MATE2K INHIBITOR, ON THE PHARMACOKINETICS OF METFORMIN IN HEALTHY VOLUNTEERS', in CLINICAL PHARMACOLOGY & THERAPEUTICS, NATURE PUBLISHING GROUP, Indianapolis, IN, pp. S64 - S64, presented at Annual Meeting of the American-Society-for-Clinical-Pharmacology-and-Therapeutics (ASCPT) / Quantitative Systems Pharmacology - An Integrating Framework for Translational Medicine Pre-Conference, Indianapolis, IN, 05 March 2013 - 09 March 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000314138700171&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Dr Sophie Stocker
    Giacomini MM; Coelho A; Stocker SL; Brett C; Castro R; Horng H; Kroetz DL, 2013, 'SLCO1B1 521T > C GENOTYPE AFFECTS THE CYCLOSPORINE-PRAVASTATIN INTERACTION', in CLINICAL PHARMACOLOGY & THERAPEUTICS, NATURE PUBLISHING GROUP, Indianapolis, IN, pp. S27 - S27, presented at Annual Meeting of the American-Society-for-Clinical-Pharmacology-and-Therapeutics (ASCPT) / Quantitative Systems Pharmacology - An Integrating Framework for Translational Medicine Pre-Conference, Indianapolis, IN, 05 March 2013 - 09 March 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000314138700073&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2009
    Dr Sophie Stocker
    Franklin ME; Anderson JM; Stocker SL; Pillans PI; Williams KM; Day RO; Taylor PJ, 2009, 'Measurement of Oxypurinol Concentrations in Urine by HPLC-Tandem Mass Spectrometry', in THERAPEUTIC DRUG MONITORING, LIPPINCOTT WILLIAMS & WILKINS, Montreal, CANADA, pp. 640 - 640, presented at 11th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology, Montreal, CANADA, 03 October 2009 - 08 October 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000270484600142&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Awards

2018    St Vincent’s Campus Rising Star Award

2013    American Society for Clinical Pharmacology and Therapeutics, Presidential Trainee Award
2010    UCSF Post-doctoral Travel Grant
2009    Australian Society of Clinical and Experimental Pharmacology and Toxicology Annual Conference, Sydney, Australia. Percy Prize Winner
2008    Dean's award for most outstanding presentation, Faculty Postgraduate Conference, University of Sydney.
2008    Travel grant, Australasian Society of Clinical and Experimental Pharmacology and Toxicology
2007    Australian Pharmaceutical Science Association Conference Pharmaceutical Practice Best Poster
2007    Dean's award for most outstanding presentation, Faculty Postgraduate Conference, University of Sydney.
2007    Travel grant, Australasian Society of Clinical and Experimental Pharmacology and Toxicology
2006 - 2009    Australian Postgraduate Award
2006     "Dorothy Thorp Prize in Science Communication", University of Sydney
2006    Travel grant, Australasian Society of Clinical and Experimental Pharmacology and Toxicology

Grants

2019    St Vincent’s Clinic Foundation - SVPHS Ladies’ Committee Sister Mary Bernice Research Grant; “Vascular effects of the sodium-glucose cotransporter 2 inhibitor empagliflozin in people with type 2 diabetes and chronic kidney disease”; Day RO, Greenfield JR, Sevastos J, Stocker S, Samocha-Bonet D, Milder T; Award amount: $120,000

2018    St Vincent’s’ Curran Foundation Endowment Award; “Metabolomics of metformin in heart failure”; Carland JE, Stocker SL, Chowdhury G; Award amount: $35,000

2018    St Vincent’s’ Curran Foundation Endowment Award; “Optimising tacrolimus therapy in lung transplant patients”; Stocker SL, Carland JE; Award amount: $30,000

2017-18 The Friends of the Mater Foundation Grant Application; “Pharmacokinetic factors associated with scalp cooling efficacy for docetaxel-containing regimens in cancer patients”; Boyle F, Dear R, Andrews K, Carland JE, Stocker SL; Award amount: $20,000

2017    UNSW Research Infrastructure Scheme; “Installation of a Shimadzu Nexera X2 UHPLC into the Department of Clinical Pharmacology and Toxicology”; Day RO, Carland JE, Stocker SL, Norris RLG, Greenfield JR; Award amount: $78,431

2017    St Vincent’s Clinic Foundation Annual Research Grant; “The safety and pharmacokinetics of metformin in heart failure”; Day RO, Macdonald P, Greenfield J, Graham G, Carland J, Stocker S; Award amount: $30,000

2011    Young Investigator Pilot Award - NIH; “Effect of genetic variation in MATE1 and OCT3 transporters on the pharmacokinetics and pharmacodynamics of metformin in healthy African Americans”; Stocker SL, Dahlin A, Giacomini K; Award amount: $10,000

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