This bulletin describes COVID-19 vaccine uptake and intention to vaccinate among a sentinel sample of people who regularly use ecstasy and other illicit stimulants in Australia. It describes barriers to vaccination among those who reported they were unsure or did not intend to be vaccinated. Multivariable logistic regression was used to establish sociodemographic, health and drug use characteristics associated with an intention to be vaccinated. The association between vaccination related attitudes and an intention to receive the COVID-19 vaccine were also explored.