This bulletin describes trends in past-year non-fatal overdose among a sentinel sample of people who regularly use ecstasy and other illicit stimulants in Darwin, the Northern Territory. It describes the substances used prior to last occasion of non-fatal overdose and resulting treatment access. It also uses multinomial logistic regression to examine sociodemographic, drug use, health, and service use differences between participants who reported a past-year non-fatal stimulant overdose or past-year non-fatal depressant overdose, and those who reported no past-year overdose.