Project Collaborators External:

• Professor Steve Allsop, National Drug and Alcohol Research Institute, Curtin University
• Professor Jakob Najman, Queensland Alcohol and Drug Research and Education Centre, University of Queensland
• Professor Elizabeth Elliott, The Children’s Hospital at Westmead, University of Sydney
• Dr Susan Jacobs, Royal Prince Alfred Hospital
• Professor Craig Olsson, Deakin Lifespan Institute, Deakin University; Murdoch Children’s Research Institute, Royal Children’s Hospital
• Dr Samantha Teague, James Cook University

Project Overview:

The Triple B Study: ‘Bumps, Babies and Beyond’ is an innovative Australian study of approximately 1,600 families. The project is a longitudinal pregnancy cohort which examines a range of biopsychosocial factors that relate to the health and development of Australian children and families. The project has a key focus on examining the impacts of substance use and mental health in pregnant women and their partners during the prenatal period on child development and family functioning.

Design and Method:

The research design involves a longitudinal pregnancy cohort study, in which pregnant women and their partners were recruited during the prenatal period (conception to birth). Participants were recruited between 2008 to 2013 from public antenatal clinics in New South Wales and Western Australia. Participants were also recruited through specialist drug and alcohol antenatal services. Families have since been followed up at key ages and stages of child development, across infancy, middle childhood and adolescence.

The Triple B Study is a multi-institutional project and is administered through Deakin University. For detailed project information, please contact the project leaders at https://lifespan.deakin.edu.au/our-research/project/triple-b-pregnancy-cohort-study-bumps-babies-and-beyond/

Benefits:

The findings from this research project will inform public health, prevention and treatment initiatives that aim to improve the health and wellbeing of children and families both in Australia and internationally.

Publications:

Pre-print:

• Weller, E., Aarsman, S., Teague, S., Greenwood, C., Youssef, G., Mattick, R., Elliott, E., Allsop, S., Burns, L., Najman, J., Jacobs, S., Olsson, C., & Hutchinson, D. (2023). Perinatal smoking in mothers and fathers: Longitudinal associations with infant birth outcomes. Addiction, 42, S184-S185. DOI: 10.31234/osf.io/hqtz2_v1

Peer-review publications:

• Schuijers, M., Greenwood, C. J., McIntosh, J. E., Youssef, G., Letcher, P., Macdonald, J. A., Spry, E., Le Bas, G., Teague, S., Biden, E., Elliott, E., Allsop, S., Burns, L., Olsson, C. A., & Hutchinson, D. M. (2024). Maternal perinatal social support and infant social-emotional problems and competencies: a longitudinal cross-cohort replication study. Archives of women's mental health. DOI: 10.1007/s00737-024-01473-x
• Rogers, A. M., Youssef, G. J., Teague, S., Sunderland, M., Le Bas, G., Macdonald, J. A., Mattick, R. P., Allsop, S., Elliott, E. J., Olsson, C. A., & Hutchinson, D. (2023). Association of maternal and paternal perinatal depression and anxiety with infant development: A longitudinal study. Journal of Affective Disorders, 338, 278-288. DOI: 10.1016/j.jad.2023.06.020
• Le Bas, G., Youssef, G., Macdonald, J. A., Teague, S., Mattick, R., Honan, I., McIntosh, J. E., Khor, S., Rossen, L., Elliott, E. J., Allsop, S., Burns, L., Olsson, C. A., & Hutchinson, D. (2022). The role of antenatal and postnatal maternal bonding in infant development. Journal of the American Academy of Child & Adolescent Psychiatry. DOI: 10.1016/j.jaac.2021.08.024
• Lowrie, N., Bas, G. L., Youssef, G., Macdonald, J. A., Teague, S., Rogers, A., Sunderland, M., Mattick, R., Elliott, E. J., Allsop, S., Burns, L., Najman, J., Jacobs, S., Olsson, C., & Hutchinson, D. (2022). Association of adolescent and young adult depression and anxiety with perinatal mental health in fathers: Findings from an Australian longitudinal study. Journal of Psychiatric Research, 156, 206-213. DOI: 10.1016/j.jpsychires.2022.10.017
• Le Bas, G. A., Youssef, G. J., Macdonald, J. A., Mattick, R., Teague, S. J., Honan, I., McIntosh, J. E., Khor, S., Rossen, L., Elliott, E. J., Allsop, S., Burns, L., Olsson, C. A., & Hutchinson, D. M. (2021). Maternal bonding, negative affect, and infant social-emotional development: A prospective cohort study [Article]. Journal of Affective Disorders(281), 926-934. DOI: 10.1016/j.jad.2020.11.031
• Britton, P. N., Walker, K., McMullan, B., Galea, C., Burrell, R., Morgan, B., Honan, I., Teutsch, S., Smithers-Sheedy, H., Fairbairn, N., Mattick, R., Hutchinson, D., & Jones, C. A. (2020). Early life parechovirus infection neurodevelopmental outcomes at 3 years: a cohort study. The Journal of Pediatrics (219), 111-117. DOI: 10.1016/j.jpeds.2019.12.026
• Rossen, L., Mattick, R. P., Wilson, J., Clare, P. J., Burns, L., Allsop, S., Elliott, E. J., Jacobs, S., Olsson, C. A., & Hutchinson, D. (2019). Mother–Infant Bonding and Emotional Availability at 12-Months of Age: The Role of Early Postnatal Bonding, Maternal Substance Use and Mental Health. Maternal & Child Health Journal, 23(12), 1686. DOI: 10.1007/s10995-019-02809-1 
• Hutchinson, D., Youssef, G., McCormack, C., Wilson, J., Allsop, S., Najman, J., Elliott, E., Burns, L., Jacobs, S., Honan, I., Rossen, L., Fiedler, H., Teague, S., Ryan, J., Olsson, C. A., & Mattick, R. P. (2019). Prenatal alcohol exposure and infant gross motor development: a prospective cohort study [Journal Article]. BMC Pediatrics, 19(149). DOI: 10.1186/s12887-019-1516-5
• Rossen, L., Mattick, R. P., Wilson, J., Burns, L., Macdonald, J. A., Olsson, C., Allsop, S., Elliott, E. J., Jacobs, S., McCormack, C., & Hutchinson, D. (2018). Mother-infant and partner-infant emotional availability at 12-months of age: findings from an Australian longitudinal study [Journal Article]. Infancy, 23(6), 893-916. DOI: 10.1111/infa.12247
• Peacock, A., Hutchinson, D., Wilson, J., McCormack, C., Bruno, R., Olsson, C., Allsop, S., Elliott, E., Burns, L., & Mattick, R. (2018). Adherence to the caffeine intake guideline during pregnancy and birth outcomes: a prospective cohort study [Journal Article]. Nutrients, 10(319). DOI: 10.3390/nu10030319
• McCormack, C., Hutchinson, D., Burns, L., Youssef, G., Wilson, J., Elliott, E., Allsop, S., Najman, J., Jacobs, S., Rossen, L., Olsson, C., & Mattick, R. (2018). Maternal and partner prenatal alcohol use and infant cognitive development. Drug and alcohol dependence, 185, 330-338. DOI: 10.1016/j.drugalcdep.2017.12.038
• Hutchinson, D., Wilson, J., Allsop, S., Elliott, E., Najman, J., Burns, L., Bartu, A., Jacobs, S., Honan, I., McCormack, C., Rossen, L., Fiedler, H., Stone, C., Khor, S., Ryan, J., Youssef, G. J., Olsson, C. A., Mattick, R. P., & Triple, B. R. C. (2018). Cohort profile: The Triple B Pregnancy Cohort Study: a longitudinal study of the relationship between alcohol, tobacco and other substance use during pregnancy and the health and well-being of Australian children and families [Journal Article]. International Journal of Epidemiology, 47(1), 26-27m. DOI: 10.1093/ije/dyx126
• Tay, R. Y., Wilson, J., McCormack, C., Allsop, S., Najman, J. M., Burns, L., Olsson, C. A., Elliott, E. J., Jacobs, S., Mattick, R. P., & Hutchinson, D. (2017). Alcohol consumption by breastfeeding mothers: Frequency, correlates and infant outcomes. Drug & Alcohol Review, 36(5), 667. DOI: 10.1111/dar.12473
• McCormack, C., Hutchinson, D., Burns, L., Wilson, J., Elliott, E., Allsop, S., Najman, J., Jacobs, S., Rossen, L., Olsson, C., & Mattick, R. (2017). Prenatal alcohol consumption between conception and recognition of pregnancy. Alcoholism: clinical and experimental research, 41(2), 369-378. DOI: 10.1111/acer.13305
• McPhie, S., Skouteris, H., Mattick, R. P., Wilson, J., Honan, I., Allsop, S., Burns, L., Elliott, E., Teague, S., Olsson, C. A., & Hutchinson, D. (2017). Weight in the First Year of Life: Associations with Maternal Prepregnancy Body Mass Index and Gestational Weight Gain-Findings from a Longitudinal Pregnancy Cohort. Am J Perinatol, 34(8), 774-779. DOI: 10.1055/s-0036-1597992
• Rossen, L., Hutchinson, D., Wilson, J., Burns, L., Allsop, S., Elliott, E. J., Jacobs, S., Macdonald, J. A., Olsson, C., & Mattick, R. P. (2017). Maternal bonding through pregnancy and postnatal: findings from an Australian longitudinal study. DOI: 10.1055/s-0037-1599052
• Rossen, L., Hutchinson, D., Wilson, J., Burns, L., Olsson, C. A., Allsop, S., Elliott, E. J., Jacobs, S., Macdonald, J. A., & Mattick, R. P. (2016). Predictors of postnatal mother-infant bonding: the role of antenatal bonding, maternal substance use and mental health. Archives of women's mental health, 19(4), 609-622. DOI: 10.1007/s00737-016-0602-z 
• Fransquet, P. D., Hutchinson, D., Olsson, C. A., Wilson, J., Allsop, S., Najman, J., Elliott, E., Mattick, R. P., Saffery, R., & Ryan, J. (2016). Perinatal maternal alcohol consumption and methylation of the dopamine receptor DRD4 in the offspring: the Triple B study. Environmental epigenetics, 2(4). DOI: 10.1093/eep/dvw023
• Fransquet, P. D., Hutchinson, D., Olsson, C. A., Allsop, S., Elliott, E. J., Burns, L., Mattick, R., Saffery, R., & Ryan, J. (2017). Cannabis use by women during pregnancy does not influence infant DNA methylation of the dopamine receptor DRD4. The American Journal of Drug and Alcohol Abuse, 43(6), 671-677. DOI: 10.1080/00952990.2017.1314488
• Rossen, L., Hutchinson, D., Wilson, J., Burns, L., Olsson, C. A., Allsop, S., Elliott, E. J., Jacobs, S., Macdonald, J. A., & Mattick, R. P. (2016). Predictors of postnatal mother-infant bonding: the role of antenatal bonding, maternal substance use and mental health. Archives of women's mental health, 19(4), 609-622. DOI: 10.1007/s00737-016-0602-z 
• McCormack, C., Hutchinson, D., Burns, L., Elliott, E., Najman, J., Allsop, S., Ollson, C., Bartu, A., Jacobs, S., & Mattick, R. (2015). Prevalence and predictors of antenatal alcohol consumption prior to awareness of pregnancy. DOI: 10.1111/acer.12741