Dr Ayad Anwer

PhD: Biology/Biophotonics, 1999-2003.

Master: Applied Science (Microscopy and Microanalysis/Biological Science), 2011-2013

Master: Biology/Histology & Physiology, 1993-1995

Bachelor: Biology /Microbiology ( Hons), 1987-1991.

Engineering

Grad Sch: Biomedical Eng

Dr Ayad Anwer is a Microbiologist, Microscopist, and biological specimen preparation expert. His Ph.D. research focused on Laser application in Biology and Biophotonics, and his Master in Microscopy and Microanalysis (USYD) focused on correlative confocal and electron Microscopy. He is currently a research associate, laboratory manager at the school of Biomedical Engineering, UNSW, and Honorary senior research fellow at the department of clinical medicine, Macquarie university. Since 2007, Dr. Anwer has been working in many areas of Biophotonics including autofluorescence of biological specimens, laser photobiomodulation, correlative microscopy, and Hyperspectral imaging.

E-mail

a.anwer@unsw.edu.au

Location

E26 Bioscience Building/ Level 1

Journal articles | 2022

Habibalahi A; Allende A; Michael J; Anwer AG; Campbell J; Mahbub SB; Bala C; Coroneo MT; Goldys EM, 2022, 'Pterygium and Ocular Surface Squamous Neoplasia: Optical Biopsy Using a Novel Autofluorescence Multispectral Imaging Technique', Cancers, vol. 14, http://dx.doi.org/10.3390/cancers14061591

Journal articles | 2021

Clement S; Anwer AG; Pires L; Campbell J; Wilson BC; Goldys EM, 2021, 'Radiodynamic therapy using tat peptide‐targeted verteporfin‐encapsulated plga nanoparticles', International Journal of Molecular Sciences, vol. 22, http://dx.doi.org/10.3390/ijms22126425

Journal articles | 2021

Gosnell ME; Staikopoulos V; Anwer AG; Mahbub SB; Hutchinson MR; Mustafa S; Goldys EM, 2021, 'Autofluorescent imprint of chronic constriction nerve injury identified by deep learning', Neurobiology of Disease, vol. 160, pp. 105528, http://dx.doi.org/10.1016/j.nbd.2021.105528

Journal articles | 2021

Mahbub SB; Nguyen LT; Habibalahi A; Campbell JM; Anwer AG; Qadri UM; Gill A; Chou A; Wong MG; Gosnell ME; Pollock CA; Saad S; Goldys EM, 2021, 'Non-invasive assessment of exfoliated kidney cells extracted from urine using multispectral autofluorescence features', Scientific Reports, vol. 11, pp. 10655, http://dx.doi.org/10.1038/s41598-021-89758-4

Journal articles | 2021

Mahbub SB; Nguyen LT; Habibalahi A; Campbell JM; Anwer AG; Qadri UM; Gill A; Chou A; Wong MG; Gosnell ME; Pollock CA; Saad S; Goldys EM, 2021, 'Publisher Correction: Non-invasive assessment of exfoliated kidney cells extracted from urine using multispectral autofluorescence features (Scientific Reports, (2021), 11, 1, (10655), 10.1038/s41598-021-89758-4)', Scientific Reports, vol. 11, pp. 18727, http://dx.doi.org/10.1038/s41598-021-96178-x

Journal articles | 2021

Peguda HK; Mahbub SB; Sherpa TD; Subedi D; Habibalahi A; Anwer AG; Gu Z; Willcox MDP; Goldys EM; Carnt NA, 2021, 'The autofluorescence patterns of acanthamoeba castellanii, pseudomonas aeruginosa and staphylococcus aureus: Effects of antibiotics and tetracaine', Pathogens, vol. 10, http://dx.doi.org/10.3390/pathogens10070894

Journal articles | 2021

Rozova VS; Anwer AG; Guller AE; Es HA; Khabir Z; Sokolova AI; Gavrilov MU; Goldys EM; Warkiani ME; Thiery JP; Zvyagin AV, 2021, 'Machine learning reveals mesenchymal breast carcinoma cell adaptation in response to matrix stiffness', PLoS Computational Biology, vol. 17, pp. e1009193, http://dx.doi.org/10.1371/journal.pcbi.1009193

Journal articles | 2021

Wang B; Chan YL; Li G; Ho KF; Anwer AG; Smith BJ; Guo H; Jalaludin B; Herbert C; Thomas PS; Liao J; Chapman DG; Foster PS; Saad S; Chen H; Oliver BG, 2021, 'Maternal particulate matter exposure impairs lung health and is associated with mitochondrial damage', Antioxidants, vol. 10, http://dx.doi.org/10.3390/antiox10071029

Journal articles | 2020

Habibalahi A; Moghari MD; Campbell JM; Anwer AG; Mahbub SB; Gosnell M; Saad S; Pollock C; Goldys EM, 2020, 'Non-invasive real-time imaging of reactive oxygen species (ROS) using auto-fluorescence multispectral imaging technique: A novel tool for redox biology', Redox Biology, vol. 34, http://dx.doi.org/10.1016/j.redox.2020.101561

Journal articles | 2020

Thejer BM; Adhikary PP; Teakel SL; Fang J; Weston PA; Gurusinghe S; Anwer AG; Gosnell M; Jazayeri JA; Ludescher M; Gray LA; Pawlak M; Wallace RH; Pant SD; Wong M; Fischer T; New EJ; Fehm TN; Neubauer H; Goldys EM; Quinn JC; Weston LA; Cahill MA, 2020, 'PGRMC1 effects on metabolism, genomic mutation and CpG methylation imply crucial roles in animal biology and disease', BMC Molecular and Cell Biology, vol. 21, http://dx.doi.org/10.1186/s12860-020-00268-z

Journal articles | 2019

Campbell JM; Habibalahi A; Mahbub S; Gosnell M; Anwer AG; Paton S; Gronthos S; Goldys E, 2019, 'Non-destructive, label free identification of cell cycle phase in cancer cells by multispectral microscopy of autofluorescence', BMC Cancer, vol. 19, http://dx.doi.org/10.1186/s12885-019-6463-x

Journal articles | 2019

Habibalahi A; Allende A; Bala C; Anwer AG; Mukhopadhyay S; Goldys EM, 2019, 'Optimized Autofluorescence Spectral Signature for Non-Invasive Diagnostics of Ocular Surface Squamous Neoplasia (OSSN)', IEEE Access, vol. 7, pp. 141343 - 141351, http://dx.doi.org/10.1109/ACCESS.2019.2942959

Journal articles | 2019

Habibalahi A; Bala C; Allende A; Anwer AG; Goldys EM, 2019, 'Novel automated non invasive detection of ocular surface squamous neoplasia using multispectral autofluorescence imaging', Ocular Surface, vol. 17, pp. 540 - 550, http://dx.doi.org/10.1016/j.jtos.2019.03.003

Journal articles | 2019

Islam K; Mahbub SB; Clement S; Guller A; Anwer AG; Goldys EM, 2019, 'Autofluorescence excitation-emission matrices as a quantitative tool for the assessment of meat quality', J Biophotonics, pp. e201900237 - e201900237, http://dx.doi.org/10.1002/jbio.201900237

Journal articles | 2019

Li G; Chan YL; Nguyen LT; Mak C; Zaky A; Anwer AG; Shi Y; Nguyen T; Pollock CA; Oliver BG; Saad S; Chen H, 2019, 'Impact of maternal e-cigarette vapor exposure on renal health in the offspring', Annals of the New York Academy of Sciences, vol. 1452, pp. 65 - 77, http://dx.doi.org/10.1111/nyas.14174

Journal articles | 2019

Li G; Chan YL; Sukjamnong S; Anwer AG; Vindin H; Padula M; Zakarya R; George J; Oliver BG; Saad S; Chen H, 2019, 'A Mitochondrial specific antioxidant reverses metabolic dysfunction and fatty liver induced by maternal cigarette smoke in mice', Nutrients, vol. 11, http://dx.doi.org/10.3390/nu11071669

Journal articles | 2019

Liu G; Bursill C; Cartland SP; Anwer AG; Parker LM; Zhang K; Feng S; He M; Inglis DW; Kavurma MM; Hutchinson MR; Goldys EM, 2019, 'A Nanoparticle-Based Affinity Sensor that Identifies and Selects Highly Cytokine-Secreting Cells', iScience, vol. 20, pp. 137 - 147, http://dx.doi.org/10.1016/j.isci.2019.09.019

Journal articles | 2019

Mahbub SB; Guller A; Campbell JM; Anwer AG; Gosnell ME; Vesey G; Goldys EM, 2019, 'Non-Invasive Monitoring of Functional State of Articular Cartilage Tissue with Label-Free Unsupervised Hyperspectral Imaging', Sci Rep, vol. 9, pp. 4398 - 4398, http://dx.doi.org/10.1038/s41598-019-40942-7

Journal articles | 2019

Zhang F; Deng F; Liu GJ; Middleton R; Inglis DW; Anwer A; Wang S; Liu G, 2019, 'IFN-γ-induced signal-on fluorescence aptasensors: From hybridization chain reaction amplification to 3D optical fiber sensing interface towards a deployable device for cytokine sensing', Molecular Systems Design and Engineering, vol. 4, pp. 872 - 881, http://dx.doi.org/10.1039/c9me00047j

Journal articles | 2019

Zhang K; Arman A; Anwer AG; Hutchinson MR; Goldys EM, 2019, 'An optical fiber based immunosensor for localized detection of IL-1Β in rat spinal cord', Sensors and Actuators, B: Chemical, vol. 282, pp. 122 - 129, http://dx.doi.org/10.1016/j.snb.2018.11.054

Journal articles | 2018

Chen H; Chan YL; Linnane C; Mao Y; Anwer AG; Sapkota A; Annissa TF; Herok G; Vissel B; Oliver BG; Saad S; Gorrie CA, 2018, 'L-Carnitine and extendin-4 improve outcomes following moderate brain contusion injury', Scientific Reports, vol. 8, http://dx.doi.org/10.1038/s41598-018-29430-6

Journal articles | 2018

Chen W; Deng W; Xu X; Zhao X; Vo JN; Anwer AG; Williams TC; Cui H; Goldys EM, 2018, 'Photoresponsive endosomal escape enhances gene delivery using liposome-polycation-DNA (LPD) nanovectors', Journal of Materials Chemistry B, vol. 6, pp. 5269 - 5281, http://dx.doi.org/10.1039/c8tb00994e

Journal articles | 2018

Ma K; Zhang F; Sayyadi N; Chen W; Anwer AG; Care A; Xu B; Tian W; Goldys EM; Liu G, 2018, '"Turn-on" Fluorescent Aptasensor Based on AIEgen Labeling for the Localization of IFN-γ in Live Cells', ACS Sensors, vol. 3, pp. 320 - 326, http://dx.doi.org/10.1021/acssensors.7b00720

Journal articles | 2018

Sukjamnong S; Chan YL; Zakarya R; Nguyen LT; Anwer AG; Zaky AA; Santiyanont R; Oliver BG; Goldys E; Pollock CA; Chen H; Saad S, 2018, 'MitoQ supplementation prevent long-term impact of maternal smoking on renal development, oxidative stress and mitochondrial density in male mice offspring', Scientific Reports, vol. 8, http://dx.doi.org/10.1038/s41598-018-24949-0

Journal articles | 2017

Clement S; Chen W; Anwer AG; Goldys EM, 2017, 'Verteprofin conjugated to gold nanoparticles for fluorescent cellular bioimaging and X-ray mediated photodynamic therapy', Microchimica Acta, vol. 184, pp. 1765 - 1771, http://dx.doi.org/10.1007/s00604-017-2145-z

Journal articles | 2017

Feng SL; Skelley AM; Anwer AG; Liu G; Inglis DW, 2017, 'Maximizing particle concentration in deterministic lateral displacement arrays', Biomicrofluidics, vol. 11, http://dx.doi.org/10.1063/1.4981014

Journal articles | 2017

Mahbub SB; Plöschner M; Gosnell ME; Anwer AG; Goldys EM, 2017, 'Statistically strong label-free quantitative identification of native fluorophores in a biological sample', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/s41598-017-15952-y

Journal articles | 2017

Rehman AU; Anwer AG; Goldys EM, 2017, 'Programmable LED-based integrating sphere light source for wide-field fluorescence microscopy', Photodiagnosis and Photodynamic Therapy, vol. 20, pp. 201 - 206, http://dx.doi.org/10.1016/j.pdpdt.2017.10.002

Journal articles | 2017

Rehman AU; Anwer AG; Gosnell ME; Mahbub SB; Liu G; Goldys EM, 2017, 'Fluorescence quenching of free and bound NADH in hela cells determined by hyperspectral imaging and unmixing of cell autofluorescence', Biomedical Optics Express, vol. 8, pp. 1488 - 1498, http://dx.doi.org/10.1364/BOE.8.001488

Journal articles | 2017

Sutton-Mcdowall ML; Gosnell M; Anwer AG; White M; Purdey M; Abell AD; Goldys EM; Thompson JG, 2017, 'Hyperspectral microscopy can detect metabolic heterogeneity within bovine post-compaction embryos incubated under two oxygen concentrations (7% versus 20%)', Human Reproduction, vol. 32, pp. 2016 - 2025, http://dx.doi.org/10.1093/humrep/dex261

Journal articles | 2016

Gosnell ME; Anwer AG; Cassano JC; Sue CM; Goldys EM, 2016, 'Functional hyperspectral imaging captures subtle details of cell metabolism in olfactory neurosphere cells, disease-specific models of neurodegenerative disorders', Biochimica et Biophysica Acta - Molecular Cell Research, vol. 1863, pp. 56 - 63, http://dx.doi.org/10.1016/j.bbamcr.2015.09.030

Journal articles | 2016

Gosnell ME; Anwer AG; Mahbub SB; Menon Perinchery S; Inglis DW; Adhikary PP; Jazayeri JA; Cahill MA; Saad S; Pollock CA; Sutton-Mcdowall ML; Thompson JG; Goldys EM, 2016, 'Quantitative non-invasive cell characterisation and discrimination based on multispectral autofluorescence features', Scientific Reports, vol. 6, http://dx.doi.org/10.1038/srep23453

Journal articles | 2015

Nguyen LT; Stangenberg S; Chen H; Al-Odat I; Chan YL; Gosnell ME; Anwer AG; Goldys EM; Pollock CA; Saad S, 2015, 'L-carnitine reverses maternal cigarette smoke exposure-induced renal oxidative stress and mitochondrial dysfunction in mouse offspring', American Journal of Physiology - Renal Physiology, vol. 308, pp. F689 - F696, http://dx.doi.org/10.1152/ajprenal.00417.2014

Journal articles | 2015

Stangenberg S; Nguyen LT; Chen H; Al-Odat I; Killingsworth MC; Gosnell ME; Anwer AG; Goldys EM; Pollock CA; Saad S, 2015, 'Oxidative stress, mitochondrial perturbations and fetal programming of renal disease induced by maternal smoking', International Journal of Biochemistry and Cell Biology, vol. 64, pp. 81 - 90, http://dx.doi.org/10.1016/j.biocel.2015.03.017

Journal articles | 2015

Wargocki P; Deng W; Anwer AG; Goldys EM, 2015, 'Medically relevant assays with a simple smartphone and tablet based fluorescence detection system', Sensors (Switzerland), vol. 15, pp. 11653 - 11664, http://dx.doi.org/10.3390/s150511653

Journal articles | 2014

Bader CA; Brooks RD; Ng YS; Sorvina A; Werrett MV; Wright PJ; Anwer AG; Brooks DA; Stagni S; Muzzioli S; Silberstein M; Skelton BW; Goldys EM; Plush SE; Shandala T; Massi M, 2014, 'Modulation of the organelle specificity in Re(i) tetrazolato complexes leads to labeling of lipid droplets', RSC Advances, vol. 4, pp. 16345 - 16351, http://dx.doi.org/10.1039/c4ra00050a

Journal articles | 2014

Drozdowicz-Tomsia K; Anwer AG; Cahill MA; Madlum KN; Maki AM; Baker MS; Goldys EM, 2014, 'Multiphoton fluorescence lifetime imaging microscopy reveals free-to-bound NADH ratio changes associated with metabolic inhibition', Journal of Biomedical Optics, vol. 19, http://dx.doi.org/10.1117/1.JBO.19.8.086016

Journal articles | 2012

Anwer AG; Gosnell ME; Perinchery SM; Inglis DW; Goldys EM, 2012, 'Visible 532 nm laser irradiation of human adipose tissue-derived stem cells: Effect on proliferation rates, mitochondria membrane potential and autofluorescence', Lasers in Surgery and Medicine, vol. 44, pp. 769 - 778, http://dx.doi.org/10.1002/lsm.22083

Journal articles | 2009

Anwer AG; Sandeep PM; Goldys EM; Vemulpad S, 2009, 'Distinctive autofluorescence of urine samples from individuals with bacteriuria compared with normals', Clinica Chimica Acta, vol. 401, pp. 73 - 75, http://dx.doi.org/10.1016/j.cca.2008.11.021
Conference Papers | 2022

Handley S; Mahbub SB; Clement S; Anwer AG; Goldys EM, 2022, 'Label-free assessment of Panc-1 cells viability and changes in metabolic fluorophores followed by radiodynamic therapy (RDT)', in Progress in Biomedical Optics and Imaging - Proceedings of SPIE, SPIE, presented at Label-free Biomedical Imaging and Sensing (LBIS) 2022, 22 January 2022 - 28 February 2022, http://dx.doi.org/10.1117/12.2608479

Conference Presentations | 2021

Campbell JM; Walters SN; Mahbub S; Habibalahi A; Anwer A; Grey ST; Goldys E, 2021, 'Pancreatic islet characterisation by the hyperspectral Assessment of autofluorescence: a non-invasive, label-free measure of viability', presented at Label-free Biomedical Imaging and Sensing (LBIS) 2021, Online, 06 March 2021 - 11 March 2021, http://dx.doi.org/10.1117/12.2578220

Conference Posters | 2021

Habibalahi A; Dashtbani M; Campbell J; Anwer A; Gosnell M; Saad S; Pollock C; Goldys E, 2021, 'Reactive oxygen species (ROS) measurement using multispectral auto-fluorescence imaging technique: a real-time and Label-free technology', Online, presented at Label-free Biomedical Imaging and Sensing (LBIS) 2021, Online, 06 March 2021 - 11 March 2021

Conference Presentations | 2021

Mahbub SB; Campbell JM; Lees FJ; Guller A; Gosnell ME; Anwer A; Crotti T; Wechalekar MD; Hutchinson MR; Goldys E, 2021, 'Quantitative label-free characterisation and discrimination of osteoarthritis and rheumatoid arthritis based on hyperspectral autofluorescence features', presented at Label-free Biomedical Imaging and Sensing (LBIS) 2021, Online only, 06 March 2021 - 11 March 2021, http://dx.doi.org/10.1117/12.2578486

Conference Papers | 2020

Feng S; Skelley AM; Anwer AG; Liu G; Inglis DW, 2020, 'Maximizing particle concentration in deterministic lateral displacement arrays', in 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017, pp. 1403 - 1404

Conference Papers | 2019

Clement S; Anwer A; Deng W; Wilson BC; Allen C; Goldys E, 2019, 'Nuclear targeted x-ray activated photodynamic therapy: a solution to treat pancreatic cancer', in Proc. SPIE. 10860, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXVIII, San Francisco, USA, presented at SPIE BIOS, San Francisco, USA, http://dx.doi.org/10.1117/12.2508957

Conference Presentations | 2019

Clement S; Anwer A; Deng W; Wilson BC; Goldys E, 2019, 'Targeted drug delivery for X-ray induced Photodynamic Therapy', presented at 10th International Nanomedicine Conference, Sydney Australia, 24 June 2019 - 26 June 2019

Conference Presentations | 2018

Islam K; Clement S; Mahbub SB; Plochner M; Anwer A; Goldys EM, 2018, 'Autofluorescence excitation – emission matrices and digital imaging as quantitative tools to determine meat quality', presented at SPIE BIOS, San Francisco, USA

Conference Papers | 2016

Gosnell ME; Anwer AG; Cassano JC; Sue CM; Mahbub SB; Pernichery SM; Inglis DW; Nadort A; Adhikary PP; Jazayeri JA; Cahill MA; Saad S; Pollock C; Sutton-McDowall ML; Thompson JG; Goldys EM, 2016, 'Non-invasive detection and monitoring of biochemistry in cells and tissues by decomposing autofluorescence', in Asia Communications and Photonics Conference, ACP

Conference Papers | 2016

Islam K; Gosnell ME; Ploschner M; Anwer AG; Goldys EM, 2016, 'Non-imaging Optics of multi-LED light source for hyperspectral imaging', in Proceedings of SPIE - The International Society for Optical Engineering, http://dx.doi.org/10.1117/12.2244670

Conference Papers | 2016

Pullen BJ; Nguyen T; Gosnell M; Anwer AG; Goldys E; Nicholls SJ; Psaltis PJ, 2016, 'Label-free assessment of endothelial cell metabolic state using autofluorescent microscopy', in Proceedings of SPIE - The International Society for Optical Engineering, http://dx.doi.org/10.1117/12.2244642

Conference Papers | 2016

Staikopoulos V; Gosnell ME; Anwer AG; Mustafa S; Hutchinson MR; Goldys EM, 2016, 'Hyperspectral imaging of endogenous fluorescent metabolic molecules to identify pain states in central nervous system tissue', in Proceedings of SPIE - The International Society for Optical Engineering, http://dx.doi.org/10.1117/12.2243158

Conference Papers | 2014

Gosnell ME; Anwer AG; Cassano JC; Sue CM; Mahbub SB; Pernichery SM; Inglis DW; Nadort A; Adhikary PP; Jazayeri JA; Cahill MA; Saad S; Pollock C; Sutton-McDowall ML; Thompson JG; Goldys EM, 2014, 'Non-invasive detection and monitoring of biochemistry in cells and tissues by decomposing autofluorescence', in Optics InfoBase Conference Papers, http://dx.doi.org/10.1364/ACPC.2016.AS3I.1

Macquarie University Research Infrastructure Block Grants Fund (RIBG) 2017, High-throughput Flow-Cytometer ($149, 000), CI.
Dr Paul Brock MND NSW Research Grant / Motor Neurone Disease Australia 2017, AI.
Macquarie University Research Seeding Grants (MQRSG) 2017. High-throughput field-deployable optical detection of biohazards relevant for national security ($50,000), AI.
Macquarie University Research Infrastructure Scheme Large, 2017, UV-Vis-Infrared Double-Beam Spectrophotometer( $91,674), AI.

1- Endeavour Post-Doctoral Research Fellowship Award /Australian Government /Dept of Education, Science, and Training – 2007. Macquarie University –Australia.

2- Macquarie University Vice-Chancellor’s Excellence Awards for Professional Staff/ Innovation and Process improvement -2017 (Shortlisted).

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Dr Ayad Anwer