Conjoint Professor

Professor David Thomas

Medicine & Health
St Vincent's Clinical School
Phone
02 93555770

Publications

  • Book Chapters | 2017
    Professor David Thomas
    Neuhaus SJ; Thomas DM, 2017, 'Multidisciplinary approach to treatment: An Australian perspective', in Sarcoma: A Multidisciplinary Approach to Treatment, Springer, pp. 461 - 476, http://dx.doi.org/10.1007/978-3-319-43121-5_23
    Book Chapters | 2017
    Professor David Thomas
    Thomas DM; Whelan J, 2017, 'Bone Sarcomas in the Adolescent and Young Adult Population', in Bleyer A; Barr R; Ries L; Whelan J; Ferrari A (ed.), Cancer in Adolescents and Young Adults., edn. 9783319336770, Springer, pp. 417 - 427, http://dx.doi.org/10.1007/978-3-319-33679-4_16
    Book Chapters | 2009
    Professor David Thomas
    Orme LM; Palmer S; Thomas D, 2009, 'No-man’s land: Between paediatric and adult medical oncology', in When Cancer Crosses Disciplines: A Physician's Handbook, pp. 885 - 906, http://dx.doi.org/10.1142/9781848163652_0035
  • Journal articles | 2021
    Professor David Thomas
    Minoche AE; Lundie B; Peters GB; Ohnesorg T; Pinese M; Thomas DM; Zankl A; Roscioli T; Schonrock N; Kummerfeld S; Burnett L; Dinger ME; Cowley MJ, 2021, 'ClinSV: clinical grade structural and copy number variant detection from whole genome sequencing data', Genome Medicine, vol. 13, http://dx.doi.org/10.1186/s13073-021-00841-x
    Journal articles | 2021
    Professor David Thomas
    Smit AK; Bartley N; Best MC; Napier CE; Butow P; Newson AJ; Tucker K; Ballinger ML; Thomas DM; Jacobs C; Meiser B; Goldstein D; Savard J; Juraskova I, 2021, 'Family communication about genomic sequencing: A qualitative study with cancer patients and relatives', Patient Education and Counseling, vol. 104, pp. 944 - 952, http://dx.doi.org/10.1016/j.pec.2020.10.022
    Journal articles | 2021
    Professor David Thomas
    Bartley N; Davies G; Butow P; Napier CE; Schlub T; Ballinger ML; Thomas DM; Juraskova I; Meiser B; Best MC, 2021, 'Fear of cancer recurrence in patients undergoing germline genome sequencing.', Support Care Cancer, http://dx.doi.org/10.1007/s00520-021-06311-9
    Journal articles | 2021
    Professor David Thomas
    Scheinberg T; Lomax A; Tattersall M; Thomas D; McCowage G; Sullivan M; Karim R; Luk PP; Mahar A; Bonar F; Bhadri VA, 2021, 'PD-1 blockade using pembrolizumab in adolescent and young adult patients with advanced bone and soft tissue sarcoma', Cancer Reports, vol. 4, http://dx.doi.org/10.1002/cnr2.1327
    Journal articles | 2021
    Professor David Thomas
    Singhal D; Hahn CN; Feurstein S; Wee LYA; Moma L; Kutyna MM; Chhetri R; Eshraghi L; Schreiber AW; Feng J; Wang PPS; Babic M; Parker WT; Gao S; Moore S; Das S; Thomas D; Pattnaik S; Brown AL; D’Andrea RJ; Poplawski NK; Thomas D; Scott HS; Godley LA; Hiwase DK, 2021, 'Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancer', Leukemia, http://dx.doi.org/10.1038/s41375-021-01246-w
    Journal articles | 2021
    Professor David Thomas
    Bartley N; Best MC; Biesecker BB; Fisher A; Goldstein D; Meiser B; Thomas DM; Ballinger ML; Butow P, 2021, 'Effectively communicating comprehensive tumor genomic profiling results: Mitigating uncertainty for advanced cancer patients', Patient Education and Counseling, http://dx.doi.org/10.1016/j.pec.2021.05.018
    Journal articles | 2021
    Professor David Thomas
    Willis AM; Smith SK; Meiser B; James PA; Ballinger ML; Thomas DM; Yanes T; Young MA, 2021, 'Influence of lived experience on risk perception among women who received a breast cancer polygenic risk score: ‘Another piece of the pie’', Journal of Genetic Counseling, http://dx.doi.org/10.1002/jgc4.1384
    Journal articles | 2021
    Professor David Thomas
    Kovac M; Woolley C; Ribi S; Blattmann C; Roth E; Morini M; Kovacova M; Ameline B; Kulozik A; Bielack S; Hartmann W; Ballinger ML; Thomas DM; Tomlinson I; Nathrath M; Heinimann K; Baumhoer D, 2021, 'Germline RET variants underlie a subset of paediatric osteosarcoma', Journal of Medical Genetics, vol. 58, pp. 20 - 24, http://dx.doi.org/10.1136/jmedgenet-2019-106734
    Journal articles | 2020
    Professor David Thomas
    Zaheed M; Tucker K; Ballinger ML; Thomas DM, 2020, 'Genotype and phenotype correlation of common cancer predisposition syndromes in sarcoma cases.', Journal of Clinical Oncology, vol. 38, pp. 1524 - 1524, http://dx.doi.org/10.1200/jco.2020.38.15_suppl.1524
    Journal articles | 2020
    Professor David Thomas
    Ballinger ML; Thomas D, 2020, 'Heritable cancer risk in the genomic era', Pathology, vol. 52, pp. S28 - S29, http://dx.doi.org/10.1016/j.pathol.2020.01.118
    Journal articles | 2020
    Professor David Thomas
    Pinese M; Lacaze P; Rath EM; Stone A; Brion MJ; Ameur A; Nagpal S; Puttick C; Husson S; Degrave D; Cristina TN; Kahl VFS; Statham AL; Woods RL; McNeil JJ; Riaz M; Barr M; Nelson MR; Reid CM; Murray AM; Shah RC; Wolfe R; Atkins JR; Fitzsimmons C; Cairns HM; Green MJ; Carr VJ; Cowley MJ; Pickett HA; James PA; Powell JE; Kaplan W; Gibson G; Gyllensten U; Cairns MJ; McNamara M; Dinger ME; Thomas DM, 2020, 'The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-019-14079-0
    Journal articles | 2020
    Professor David Thomas
    Kalachand RD; Stordal B; Madden S; Chandler B; Cunningham J; Goode EL; Ruscito I; Braicu EI; Sehouli J; Ignatov A; Yu H; Katsaros D; Mills GB; Lu KH; Carey MS; Timms KM; Kupryjanczyk J; Rzepecka IK; Podgorska A; McAlpine JN; Swisher EM; Bernards SS; O'Riain C; O'Toole S; O'Leary JJ; Bowtell DD; Thomas DM; Prieske K; Joosse SA; Woelber L; Chaudhry P; Häfner N; Runnebaum IB; Hennessy BT, 2020, 'BRCA1 Promoter Methylation and Clinical Outcomes in Ovarian Cancer: An Individual Patient Data Meta-Analysis', Journal of the National Cancer Institute, vol. 112, pp. 1190 - 1203, http://dx.doi.org/10.1093/jnci/djaa070
    Journal articles | 2020
    Professor David Thomas
    Demetri GD; Antonescu CR; Bjerkehagen B; Bovée JVMG; Boye K; Chacón M; Dei Tos AP; Desai J; Fletcher JA; Gelderblom H; George S; Gronchi A; Haas RL; Hindi N; Hohenberger P; Joensuu H; Jones RL; Judson I; Kang YK; Kawai A; Lazar AJ; Le Cesne A; Maestro R; Maki RG; Martín J; Patel S; Penault-Llorca F; Premanand Raut C; Rutkowski P; Safwat A; Sbaraglia M; Schaefer IM; Shen L; Serrano C; Schöffski P; Stacchiotti S; Sundby Hall K; Tap WD; Thomas DM; Trent J; Valverde C; van der Graaf WTA; von Mehren M; Wagner A; Wardelmann E; Naito Y; Zalcberg J; Blay JY, 2020, 'Diagnosis and management of tropomyosin receptor kinase (TRK) fusion sarcomas: expert recommendations from the World Sarcoma Network', Annals of Oncology, vol. 31, pp. 1506 - 1517, http://dx.doi.org/10.1016/j.annonc.2020.08.2232
    Journal articles | 2020
    Professor David Thomas
    Bartley N; Best M; Jacobs C; Juraskova I; Newson AJ; Savard J; Meiser B; Ballinger ML; Thomas DM; Biesecker B; Butow P, 2020, 'Cancer patients' views and understanding of genome sequencing: A qualitative study', Journal of Medical Genetics, vol. 57, pp. 671 - 676, http://dx.doi.org/10.1136/jmedgenet-2019-106410
    Journal articles | 2020
    Professor David Thomas
    Dancsok AR; Gao D; Lee AF; Steigen SE; Blay JY; Thomas DM; Maki RG; Nielsen TO; Demicco EG, 2020, 'Tumor-associated macrophages and macrophage-related immune checkpoint expression in sarcomas', OncoImmunology, vol. 9, http://dx.doi.org/10.1080/2162402X.2020.1747340
    Journal articles | 2020
    Professor David Thomas
    Best MC; Butow P; Jacobs C; Savard J; Biesecker B; Ballinger ML; Bartley N; Davies G; Napier CE; Smit AK; Thomas DM; Newson AJ, 2020, 'Who should access germline genome sequencing? A mixed methods study of patient views', Clinical Genetics, vol. 97, pp. 329 - 337, http://dx.doi.org/10.1111/cge.13664
    Journal articles | 2020
    Professor David Thomas
    Butow P; Davies G; Napier C; Thomas DM; Bartley N; Goldstein D; Ballinger ML; Juraskova I; Schlub TE; Tucker K; Meiser B; Young M-A, 2020, 'Return of results after somatic tumor mutation profiling in advanced cancer: Psychological impacts.', Journal of Clinical Oncology, vol. 38, pp. 1541 - 1541, http://dx.doi.org/10.1200/jco.2020.38.15_suppl.1541
    Journal articles | 2020
    Professor David Thomas
    Wong M; Mayoh C; Lau LMS; Khuong-Quang DA; Pinese M; Kumar A; Barahona P; Wilkie EE; Sullivan P; Bowen-James R; Syed M; Martincorena I; Abascal F; Sherstyuk A; Bolanos NA; Baber J; Priestley P; Dolman MEM; Fleuren EDG; Gauthier ME; Mould EVA; Gayevskiy V; Gifford AJ; Grebert-Wade D; Strong PA; Manouvrier E; Warby M; Thomas DM; Kirk J; Tucker K; O’Brien T; Alvaro F; McCowage GB; Dalla-Pozza L; Gottardo NG; Tapp H; Wood P; Khaw SL; Hansford JR; Moore AS; Norris MD; Trahair TN; Lock RB; Tyrrell V; Haber M; Marshall GM; Ziegler DS; Ekert PG; Cowley MJ, 2020, 'Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer', Nature Medicine, vol. 26, pp. 1742 - 1753, http://dx.doi.org/10.1038/s41591-020-1072-4
    Journal articles | 2020
    Professor David Thomas
    Mirabello L; Zhu B; Koster R; Karlins E; Dean M; Yeager M; Gianferante M; Spector LG; Morton LM; Karyadi D; Robison LL; Armstrong GT; Bhatia S; Song L; Pankratz N; Pinheiro M; Gastier-Foster JM; Gorlick R; De Toledo SRC; Petrilli AS; Patino-Garcia A; Lecanda F; Gutierrez-Jimeno M; Serra M; Hattinger C; Picci P; Scotlandi K; Flanagan AM; Tirabosco R; Amary MF; Kurucu N; Ilhan IE; Ballinger ML; Thomas DM; Barkauskas DA; Mejia-Baltodano G; Valverde P; Hicks BD; Wang M; Hutchinson AA; Tucker M; Sampson J; Landi MT; Freedman ND; Gapstur S; Carter B; Hoover RN; Chanock SJ; Savage SA, 2020, 'Frequency of Pathogenic Germline Variants in Cancer-Susceptibility Genes in Patients with Osteosarcoma', JAMA Oncology, vol. 6, pp. 724 - 734, http://dx.doi.org/10.1001/jamaoncol.2020.0197
    Journal articles | 2020
    Professor David Thomas
    Cipponi A; Goode DL; Bedo J; McCabe MJ; Pajic M; Croucher DR; Rajal AG; Junankar SR; Saunders DN; Lobachevsky P; Papenfuss AT; Nessem D; Nobis M; Warren SC; Timpson P; Cowley M; Vargas AC; Qiu MR; Generali DG; Keerthikumar S; Nguyen U; Corcoran NM; Long GV; Blay J-Y; Thomas DM; McCabe M, 2020, 'MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer', Science
    Journal articles | 2020
    Professor David Thomas
    Joshua AM; Prawira A; Thavaneswaran S; Cosman R; Lee CK; Sjoquist KM; Simes J; Thomas DM; Espinoza D; Sebastian L; Ballinger ML; Hague W; Chinchen S; Collignon E; Kansara M; Palacios T; Grady J; Barker H; Thornton K, 2020, 'A signal-seeking trial of olaparib and durvalumab in homologous repair-deficient tumors: A sub-study of the cancer molecular screening and therapeutics (MoST) program.', Journal of Clinical Oncology, vol. 38, pp. 3073 - 3073, http://dx.doi.org/10.1200/jco.2020.38.15_suppl.3073
    Journal articles | 2020
    Professor David Thomas
    Shin SJ; Dodd-Eaton EB; Peng G; Bojadzieva J; Chen J; Amos CI; Frone MN; Khincha PP; Mai PL; Savage SA; Ballinger ML; Thomas DM; Yuan Y; Strong LC; Wang W, 2020, 'Penetrance of different cancer types in families with Li-Fraumeni syndrome: A validation study using multicenter cohorts', Cancer Research, vol. 80, pp. 354 - 360, http://dx.doi.org/10.1158/0008-5472.CAN-19-0728
    Journal articles | 2020
    Professor David Thomas
    Heyer EE; Deveson IW; Wooi D; Selinger CI; Lyons RJ; Hayes VM; O’Toole SA; Ballinger ML; Gill D; Thomas DM; Mercer TR; Blackburn J, 2020, 'Author Correction: Diagnosis of fusion genes using targeted RNA sequencing (Nature Communications, (2019), 10, 1, (1388), 10.1038/s41467-019-09374-9)', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-020-15697-9
    Journal articles | 2020
    Professor David Thomas
    Davies G; Butow P; Napier CE; Bartley N; Juraskova I; Meiser B; Ballinger ML; Thomas DM; Schlub TE; Best MC, 2020, 'Advanced Cancer Patient Knowledge of and Attitudes towards Tumor Molecular Profiling', Translational Oncology, vol. 13, pp. 100799, http://dx.doi.org/10.1016/j.tranon.2020.100799
    Journal articles | 2020
    Professor David Thomas
    Butow P; Butow P; Davies G; Napier CE; Schlub T; Best MC; Bartley N; Juraskova I; Meiser B; Ballinger ML; Biesecker B; Goldstein D; Thomas DM, 2020, 'Assessment of the Value of Tumor Variation Profiling Perceived by Patients with Cancer', JAMA Network Open, vol. 3, pp. e204721, http://dx.doi.org/10.1001/jamanetworkopen.2020.4721
    Journal articles | 2019
    Professor David Thomas
    McCabe MJ; Pinese M; Chan CL; Sheriff N; Thompson TJ; Grady J; Wong M; Gauthier MEA; Puttick C; Gayevskiy V; Hajdu E; Wong SQ; Barrett W; Earls P; Lukeis R; Cheng YY; Lin RCY; Thomas DM; Watkins DN; Dinger ME; McCormack AI; Cowley MJ, 2019, 'Genomic stratification and liquid biopsy in a rare adrenocortical carcinoma (ACC) case, with dual lung metastases', Cold Spring Harbor Molecular Case Studies, vol. 5, http://dx.doi.org/10.1101/mcs.a003764
    Journal articles | 2019
    Professor David Thomas
    Tap WD; Gelderblom H; Palmerini E; Desai J; Bauer S; Blay JY; Alcindor T; Ganjoo K; Martín-Broto J; Ryan CW; Thomas DM; Peterfy C; Healey JH; van de Sande M; Gelhorn HL; Shuster DE; Wang Q; Yver A; Hsu HH; Lin PS; Tong-Starksen S; Stacchiotti S; Wagner AJ, 2019, 'Pexidartinib versus placebo for advanced tenosynovial giant cell tumour (ENLIVEN): a randomised phase 3 trial', The Lancet, vol. 394, pp. 478 - 487, http://dx.doi.org/10.1016/S0140-6736(19)30764-0
    Journal articles | 2019
    Professor David Thomas
    Fortuno C; Cipponi A; Ballinger ML; Tavtigian SV; Olivier M; Ruparel V; Haupt Y; Haupt S; Study ISK; Tucker K; Spurdle AB; Thomas DM; James PA, 2019, 'A quantitative model to predict pathogenicity of missense variants in the TP53 gene', Human Mutation, vol. 40, pp. 788 - 800, http://dx.doi.org/10.1002/humu.23739
    Journal articles | 2019
    Professor David Thomas
    Best MC; Bartley N; Jacobs C; Juraskova I; Goldstein D; Newson AJ; Savard J; Meiser B; Ballinger M; Napier C; Thomas D; Biesecker B; Butow P; Tucker K; Schlub T; Vines R; Vines K; Kirk J; Young MA, 2019, 'Patient perspectives on molecular tumor profiling: "why wouldn't you?"', BMC Cancer, vol. 19, pp. 753, http://dx.doi.org/10.1186/s12885-019-5920-x
    Journal articles | 2019
    Professor David Thomas
    Thavaneswaran S; Rath E; Tucker K; Joshua AM; Hess D; Pinese M; Ballinger ML; Thomas DM, 2019, 'Therapeutic implications of germline genetic findings in cancer', Nature Reviews Clinical Oncology, vol. 16, pp. 386 - 396, http://dx.doi.org/10.1038/s41571-019-0179-3
    Journal articles | 2019
    Professor David Thomas
    Vargas AC; Selinger C; Satgunaseelan L; Cooper WA; Gupta R; Stalley P; Brown W; Soper J; Schatz J; Boyle R; Thomas DM; Tattersall MHN; Bhadri V; Maclean F; Bonar SF; Scolyer RA; Karim RZ; McCarthy SW; Mahar A; O'Toole SA, 2019, 'FISH analysis of selected soft tissue tumors: Diagnostic experience in a tertiary center', Asia-Pacific Journal of Clinical Oncology, vol. 15, pp. 38 - 47, http://dx.doi.org/10.1111/ajco.12980
    Journal articles | 2019
    Professor David Thomas
    Heyer EE; Deveson IW; Wooi D; Selinger CI; Lyons RJ; Hayes VM; O’Toole SA; Ballinger ML; Gill D; Thomas DM; Mercer TR; Blackburn J, 2019, 'Diagnosis of fusion genes using targeted RNA sequencing', Nature Communications, vol. 10, http://dx.doi.org/10.1038/s41467-019-09374-9
    Journal articles | 2019
    Professor David Thomas
    Kansara M; Thomson K; Pang P; Dutour A; Mirabello L; Acher F; Pin JP; Demicco EG; Yan J; Teng MWL; Smyth MJ; Thomas DM, 2019, 'Infiltrating myeloid cells drive osteosarcoma progression via GRM4 regulation of IL23', Cancer Discovery, vol. 9, pp. 1511 - 1519, http://dx.doi.org/10.1158/2159-8290.CD-19-0154
    Journal articles | 2019
    Professor David Thomas
    Dancsok AR; Setsu N; Gao D; Blay JY; Thomas D; Maki RG; Nielsen TO; Demicco EG, 2019, 'Expression of lymphocyte immunoregulatory biomarkers in bone and soft-tissue sarcomas', Modern Pathology, vol. 32, pp. 1772 - 1785, http://dx.doi.org/10.1038/s41379-019-0312-y
    Journal articles | 2019
    Professor David Thomas
    Lacaze P; Pinese M; Kaplan W; Stone A; Brion MJ; Woods RL; McNamara M; McNeil JJ; Dinger ME; Thomas DM, 2019, 'The Medical Genome Reference Bank: a whole-genome data resource of 4000 healthy elderly individuals. Rationale and cohort design', European Journal of Human Genetics, vol. 27, pp. 308 - 316, http://dx.doi.org/10.1038/s41431-018-0279-z
    Journal articles | 2019
    Professor David Thomas
    Jones RM; Melton PE; Pinese M; Rea AJ; Ingley E; Ballinger ML; Wood DJ; Thomas DM; Moses EK, 2019, 'Identification of novel sarcoma risk genes using a two-stage genome wide DNA sequencing strategy in cancer cluster families and population case and control cohorts', BMC Medical Genetics, vol. 20, http://dx.doi.org/10.1186/s12881-019-0808-9
    Journal articles | 2019
    Professor David Thomas
    Thavaneswaran S; Napier C; Goldstein D; Meiser B; Butow P; Thomas DM; Ballinger ML; Best M, 2019, 'Medical oncologists’ experience with returning molecular tumor profiling to patients.', Journal of Clinical Oncology, vol. 37, pp. 10521 - 10521, http://dx.doi.org/10.1200/jco.2019.37.15_suppl.10521
    Journal articles | 2019
    Professor David Thomas
    Thavaneswaran S; Rath E; Tucker K; Joshua AM; Hess D; Pinese M; Ballinger ML; Thomas DM, 2019, 'Author Correction: Therapeutic implications of germline genetic findings in cancer (Nature Reviews Clinical Oncology, (2019), 16, 6, (386-396), 10.1038/s41571-019-0179-3)', Nature Reviews Clinical Oncology, vol. 16, pp. 397, http://dx.doi.org/10.1038/s41571-019-0212-6
    Journal articles | 2019
    Professor David Thomas
    Puttick C; Kumar K; Davis R; Pinese M; Thomas D; Dinger M; Sue C; Cowley M, 2019, 'mity: A highly sensitive mitochondrial variant analysis pipeline for whole genome sequencing data', , http://dx.doi.org/10.1101/852210
    Journal articles | 2018
    Professor David Thomas
    Willis AM; Smith SK; Meiser B; Ballinger ML; Thomas DM; Tattersall M; Young MA, 2018, 'Development and Pilot Testing of a Decision Aid for Genomic Research Participants Notified of Clinically Actionable Research Findings for Cancer Risk', Journal of Genetic Counseling, vol. 27, pp. 1055 - 1066, http://dx.doi.org/10.1007/s10897-018-0223-y
    Journal articles | 2018
    Professor David Thomas
    Chan EKF; Cameron DL; Petersen DC; Lyons RJ; Baldi BF; Papenfuss AT; Thomas DM; Hayes VM, 2018, 'Optical mapping reveals a higher level of genomic architecture of chained fusions in cancer', Genome Research, vol. 28, pp. 726 - 738, http://dx.doi.org/10.1101/gr.227975.117
    Journal articles | 2018
    Professor David Thomas
    Best M; Newson AJ; Meiser B; Juraskova I; Goldstein D; Tucker K; Ballinger ML; Hess D; Schlub TE; Biesecker B; Vines R; Vines K; Thomas D; Young MA; Savard J; Jacobs C; Butow P, 2018, 'The PiGeOn project: Protocol of a longitudinal study examining psychosocial and ethical issues and outcomes in germline genomic sequencing for cancer', BMC Cancer, vol. 18, http://dx.doi.org/10.1186/s12885-018-4366-x
    Journal articles | 2018
    Professor David Thomas
    Liu Z; Martin J; Orme L; Seddon B; Desai J; Nicholls W; Thomson D; Porter D; McCowage G; Underhill C; Cranswick N; Michael M; Zacharin M; Herschtal A; Sivasuthan J; Thomas DM, 2018, 'Gender differences in doxorubicin pharmacology for subjects with chemosensitive cancers of young adulthood', Cancer Chemotherapy and Pharmacology, vol. 82, pp. 887 - 898, http://dx.doi.org/10.1007/s00280-018-3683-8
    Journal articles | 2018
    Professor David Thomas
    Walczak A; Patterson P; Thomas D, 2018, 'Trials and tribulations: improving outcomes for adolescents and young adults with rare and low survival cancers', The Medical journal of Australia, vol. 209, pp. 330 - 332, http://dx.doi.org/10.5694/mja17.00976
    Journal articles | 2018
    Professor David Thomas
    Gounder MM; Thomas DM; Tap WD, 2018, 'Locally aggressive connective tissue tumors', Journal of Clinical Oncology, vol. 36, pp. 202 - 209, http://dx.doi.org/10.1200/JCO.2017.75.8482
    Journal articles | 2018
    Professor David Thomas
    Thavaneswaran S; Sebastian L; Ballinger M; Best M; Hess D; Lee CK; Sjoquist KM; Hague WE; Butow PN; Simes RJ; Thomas D, 2018, 'Cancer Molecular Screening and Therapeutics (MoST): a framework for multiple, parallel signal-seeking studies of targeted therapies for rare and neglected cancers', The Medical journal of Australia, vol. 209, pp. 354 - 355, http://dx.doi.org/10.5694/mja18.00227
    Journal articles | 2018
    Professor David Thomas
    Koster R; Panagiotou OA; Wheeler WA; Karlins E; Gastier-Foster JM; Caminada de Toledo SR; Petrilli AS; Flanagan AM; Tirabosco R; Andrulis IL; Wunder JS; Gokgoz N; Patiño-Garcia A; Lecanda F; Serra M; Hattinger C; Picci P; Scotlandi K; Thomas DM; Ballinger ML; Gorlick R; Barkauskas DA; Spector LG; Tucker M; Belynda DH; Yeager M; Hoover RN; Wacholder S; Chanock SJ; Savage SA; Mirabello L, 2018, 'Genome-wide association study identifies the GLDC/IL33 locus associated with survival of osteosarcoma patients', International Journal of Cancer, vol. 142, pp. 1594 - 1601, http://dx.doi.org/10.1002/ijc.31195
    Journal articles | 2018
    Professor David Thomas
    Woodcock F; Doble B; Fox SB; Collins I; Hayes T; Singh M; Richardson G; Lipton L; Moon SY; Lucas M; Fellowes A; Xu H; Thorne H; McNeil JJ; Lorgelly P; Thomas DM; James PA; John T; Risbridger G; Wright G; Snyder R, 2018, 'Mapping the EORTC-QLQ-C30 to the EQ-5D-3L: An Assessment of Existing and Newly Developed Algorithms', Medical Decision Making, vol. 38, pp. 954 - 967, http://dx.doi.org/10.1177/0272989X18797588
    Journal articles | 2018
    Professor David Thomas
    Rasmussen V; Forrest LE; Rogasik M; Girodet M; Meeus P; Sunyach MP; Blay JY; Bally O; Brahmi M; Ballinger ML; Niedermayr E; Thomas DM; Halliday J; James P; Ray-Coquard I; Young MA, 2018, 'A comparison of Australian and French families affected by sarcoma: Perceptions of genetics and incidental findings', Personalized Medicine, vol. 15, pp. 13 - 24, http://dx.doi.org/10.2217/pme-2017-0035
    Journal articles | 2017
    Professor David Thomas
    Fleuren EDG; Vlenterie M; Van Der Graaf WTA; Hillebrandt-Roeffen MHS; Blackburn J; Ma X; Chan H; Magias MC; Van Erp A; Van Houdt L; Cebeci SAS; Van De Ven A; Flucke UE; Heyer EE; Thomas DM; Lord CJ; Marini KD; Vaghjiani V; Mercer TR; Cain JE; Wu J; Versleijen-Jonkers YMH; Daly RJ, 2017, 'Phosphoproteomic profiling reveals ALK and MET as novel actionable targets across synovial sarcoma subtypes', Cancer Research, vol. 77, pp. 4279 - 4292, http://dx.doi.org/10.1158/0008-5472.CAN-16-2550
    Journal articles | 2017
    Professor David Thomas
    Takeda K; Nakayama M; Hayakawa Y; Kojima Y; Ikeda H; Imai N; Ogasawara K; Okumura K; Thomas DM; Smyth MJ, 2017, 'IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting', Nature Communications, vol. 8, http://dx.doi.org/10.1038/ncomms14607
    Journal articles | 2017
    Professor David Thomas
    Ballinger ML; Best A; Mai PL; Khincha PP; Loud JT; Peters JA; Achatz MI; Chojniak R; Balieiro Da Costa A; Santiago KM; Garber J; O'Neill AF; Eeles RA; Evans DG; Bleiker E; Sonke GS; Ruijs M; Loo C; Schiffman J; Naumer A; Kohlmann W; Strong LC; Bojadzieva J; Malkin D; Rednam SP; Stoffel EM; Koeppe E; Weitzel JN; Slavin TP; Nehoray B; Robson M; Walsh M; Manelli L; Villani A; Thomas DM; Savage SA, 2017, 'Baseline surveillance in li-fraumeni syndrome using whole-body magnetic resonance imaging ameta-analysis', JAMA Oncology, vol. 3, pp. 1634 - 1639, http://dx.doi.org/10.1001/jamaoncol.2017.1968
    Journal articles | 2017
    Professor David Thomas
    Willis AM; Smith SK; Meiser B; Ballinger ML; Thomas DM; Young MA, 2017, 'Sociodemographic, psychosocial and clinical factors associated with uptake of genetic counselling for hereditary cancer: a systematic review', Clinical Genetics, vol. 92, pp. 121 - 133, http://dx.doi.org/10.1111/cge.12868
    Journal articles | 2017
    Professor David Thomas
    McBride KA; Ballinger ML; Schlub TE; Young MA; Tattersall MHN; Kirk J; Eeles R; Killick E; Walker LG; Shanley S; Thomas DM; Mitchell G, 2017, 'Psychosocial morbidity in TP53 mutation carriers: is whole-body cancer screening beneficial?', Familial Cancer, vol. 16, pp. 423 - 432, http://dx.doi.org/10.1007/s10689-016-9964-7
    Journal articles | 2017
    Professor David Thomas
    Lorgelly PK; Doble B; Rowen D; Brazier J; Thomas DM; Fox SB; Thorne H; Parisot JP; Doig K; Fellowes A; Dobrovic A; James PA; Lipton L; Ashley D; Hayes T; McMurrick P; Richardson G; Lucas M; McNeil JJ; John T, 2017, 'Condition-specific or generic preference-based measures in oncology? A comparison of the EORTC-8D and the EQ-5D-3L', Quality of Life Research, vol. 26, pp. 1163 - 1176, http://dx.doi.org/10.1007/s11136-016-1443-y
    Journal articles | 2017
    Professor David Thomas
    Leung DH; Heltshe SL; Borowitz D; Gelfond D; Kloster M; Heubi JE; Stalvey M; Ramsey BW; Stecenko A; Schechter M; Hunter E; Hoover W; Hathorne H; Brand K; Filbrun A; Linn M; Borowitz D; Caci N; McWilliams B; Brazil I; Heubi J; Bushman M; McColley S; Bowen A; McCoy K; Sakellaris K; Sharma P; Cannon C; Hebert A; Sagel S; Anthony M; Dyson M; Urbanek H; Millard S; Gile C; Graff G; Allwein L; Hiatt P; Schaap N; Krupp N; Bendy L; Ahrens R; Teresi M; Berlinski A; Ramsey LL; McNamara J; Johnson M; Brown R; Berry P; Mehdi N; Royall J; Thomas D; Rubenstein R; Donnelly E; Weiner D; Hurban S; Hartigan E; Powers M; Simmons K; Chatfield B; Oldroyd H; Hoffman L; McNamara S; Wooldridge J; Cooper A; Faro A; Rodgers D; Fortner C; Suttmore V; Hocevar-Trnka J; Skalland M; Fowler A, 2017, 'Effects of diagnosis by newborn screening for cystic fibrosis on weight and length in the first year of life', JAMA Pediatrics, vol. 171, pp. 546 - 554, http://dx.doi.org/10.1001/jamapediatrics.2017.0206
    Journal articles | 2017
    Professor David Thomas
    Thomas DM, 2017, 'Is Li–Fraumeni syndrome really much more common?', Human Mutation, vol. 38, pp. 1619, http://dx.doi.org/10.1002/humu.23342
    Journal articles | 2017
    Professor David Thomas
    Ballinger ML; Ferris NJ; Moodie K; Mitchell G; Shanley S; James PA; Thomas DM, 2017, 'Surveillance in Germline TP53 Mutation Carriers Utilizing Whole-Body Magnetic Resonance Imaging', JAMA oncology, vol. 3, pp. 1735 - 1736, http://dx.doi.org/10.1001/jamaoncol.2017.1355
    Journal articles | 2017
    Professor David Thomas
    Doble B; John T; Thomas D; Fellowes A; Fox S; Lorgelly P, 2017, 'Cost-effectiveness of precision medicine in the fourth-line treatment of metastatic lung adenocarcinoma: An early decision analytic model of multiplex targeted sequencing', Lung Cancer, vol. 107, pp. 22 - 35, http://dx.doi.org/10.1016/j.lungcan.2016.05.024
    Journal articles | 2017
    Professor David Thomas
    Peng G; Bojadzieva J; Ballinger ML; Li J; Blackford AL; Mai PL; Savage SA; Thomas DM; Strong LC; Wang W, 2017, 'Estimating TP53 mutation carrier probability in families with li-fraumeni syndrome using LFSPRO', Cancer Epidemiology Biomarkers and Prevention, vol. 26, pp. 837 - 844, http://dx.doi.org/10.1158/1055-9965.EPI-16-0695
    Journal articles | 2016
    Professor David Thomas
    Kager L; Whelan J; Dirksen U; Hassan B; Anninga J; Bennister L; Bovee JVMG; Brennan B; Broto JM; Brugieres L; Cleton-Jansen A-M; Copland C; Dutour A; Fagioli F; Ferrari S; Fiocco M; Fleuren E; Gaspar N; Gelderblom H; Gerrand C; Gerss J; Gonzato O; van der Graaf W; Hecker-Nolting S; Herrero-Martin D; Klco-Brosius S; Kovar H; Ladenstein R; Lancia C; LeDeley M-C; McCabe MG; Metzler M; Myklebost O; Nathrath M; Picci P; Potratz J; Redini F; Richter GHS; Reinke D; Rutkowski P; Scotlandi K; Strauss S; Thomas D; Tirado OM; Tirode F; Vassal G; Bielack SS, 2016, 'The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report', CLINICAL SARCOMA RESEARCH, vol. 6, http://dx.doi.org/10.1186/s13569-016-0043-5
    Journal articles | 2016
    Professor David Thomas
    Burgess A; Chia KM; Haupt S; Thomas D; Haupt Y; Lim E, 2016, 'Clinical overview of MDM2/X-targeted therapies', Frontiers in Oncology, vol. 6, http://dx.doi.org/10.3389/fonc.2016.00007
    Journal articles | 2016
    Professor David Thomas
    Ballinger ML; Goode DL; Ray-Coquard I; James PA; Mitchell G; Niedermayr E; Puri A; Schiffman JD; Dite GS; Cipponi A; Maki RG; Brohl AS; Myklebost O; Stratford EW; Lorenz S; Ahn SM; Ahn JH; Kim JE; Shanley S; Beshay V; Randall RL; Judson I; Seddon B; Campbell IG; Young MA; Sarin R; Blay JY; O'Donoghue SI; Thomas DM, 2016, 'Monogenic and polygenic determinants of sarcoma risk: an international genetic study', The Lancet Oncology, vol. 17, pp. 1261 - 1271, http://dx.doi.org/10.1016/S1470-2045(16)30147-4
    Journal articles | 2016
    Professor David Thomas
    Vargas AC; Selinger CI; Satgunaseelan L; Cooper WA; Gupta R; Stalley P; Brown W; Soper J; Schatz J; Boyle R; Thomas DM; Tattersall MHN; Bhadri VA; Maclean F; Bonar SF; Scolyer RA; Karim RZ; McCarthy SW; Mahar A; O'Toole SA, 2016, 'Atypical Ewing sarcoma breakpoint region 1 fluorescence in-situ hybridization signal patterns in bone and soft tissue tumours: diagnostic experience with 135 cases', Histopathology, vol. 69, pp. 1000 - 1011, http://dx.doi.org/10.1111/his.13031
    Journal articles | 2016
    Professor David Thomas
    McBride KA; Hallowell N; Tattersall MHN; Kirk J; Ballinger ML; Thomas DM; Mitchell G; Young MA, 2016, 'Timing and context: important considerations in the return of genetic results to research participants', Journal of Community Genetics, vol. 7, pp. 11 - 20, http://dx.doi.org/10.1007/s12687-015-0231-7
    Journal articles | 2016
    Professor David Thomas
    Lomax AJ; Beith J; Bhadri V; Boyer M; Grimison P; Horvath LG; Kao S; Tattersall M; Thomas D; McNeil C, 2016, 'Outcomes of patients with non-melanoma solid tumours receiving self-funded pembrolizumab at Chris O'Brien Lifehouse', Internal Medicine Journal, vol. 46, pp. 1392 - 1398, http://dx.doi.org/10.1111/imj.13232
    Journal articles | 2016
    Professor David Thomas
    Lorgelly PK; Doble B; Knott RJ; Thomas DM; Fox SB; Thorne H; Parisot JP; Doig K; Fellowes A; Dobrovic A; Fellowes A; Lipton L; Ashley D; Hayes T; McMurrick P; Richardson G; Lucas M; McNeil JJ; John T, 2016, 'Realising the Value of Linked Data to Health Economic Analyses of Cancer Care: A Case Study of Cancer 2015', PharmacoEconomics, vol. 34, pp. 139 - 154, http://dx.doi.org/10.1007/s40273-015-0343-2
    Journal articles | 2016
    Professor David Thomas
    Ballinger ML; Thomas DM, 2016, 'Sarcoma and germ-line DICER1 mutations – Authors’ reply', The Lancet Oncology, vol. 17, pp. e471, http://dx.doi.org/10.1016/S1470-2045(16)30527-7
    Journal articles | 2016
    Professor David Thomas
    Gaston CL; Grimer RJ; Parry M; Stacchiotti S; Tos APD; Gelderblom H; Ferrari S; Baldi GG; Jones RL; Chawla S; Casali P; LeCesne A; Blay J-Y; Dijkstra SPD; Thomas DM; Rutkowski P, 2016, 'Current status and unanswered questions on the use of Denosumab in giant cell tumor of bone', CLINICAL SARCOMA RESEARCH, vol. 6, http://dx.doi.org/10.1186/s13569-016-0056-0
    Journal articles | 2016
    Professor David Thomas
    Thomas DM; Ballinger ML, 2016, 'Diagnosis and management of hereditary sarcoma', Recent Results in Cancer Research, vol. 205, pp. 169 - 189, http://dx.doi.org/10.1007/978-3-319-29998-3_10
    Journal articles | 2016
    Professor David Thomas
    Ngiow SF; Loi S; Thomas D; Smyth MJ, 2016, 'Mouse Models of Tumor Immunotherapy', Tumor immunology, vol. 130, pp. 1 - 24, http://dx.doi.org/10.1016/bs.ai.2015.12.004
    Journal articles | 2016
    Professor David Thomas
    Thomas D, 2016, 'International survey of awareness of genetic risk in the clinical sarcoma community', Asia Pac J Clin Oncol, vol. 12, pp. 133 - 142, http://dx.doi.org/10.1111/ajco.12457
    Journal articles | 2015
    Professor David Thomas
    Sampson JN; Wheeler WA; Yeager M; Panagiotou O; Wang Z; Berndt SI; Lan Q; Abnet CC; Amundadottir LT; Figueroa JD; Landi MT; Mirabello L; Savage SA; Taylor PR; De Vivo I; McGlynn KA; Purdue MP; Rajaraman P; Adami HO; Ahlbom A; Albanes D; Amary MF; An SJ; Andersson U; Andriole G; Andrulis IL; Angelucci E; Ansell SM; Arici C; Armstrong BK; Arslan AA; Austin MA; Baris D; Barkauskas DA; Bassig BA; Becker N; Benavente Y; Benhamou S; Berg C; Van Den Berg D; Bernstein L; Bertrand KA; Birmann BM; Black A; Boeing H; Boffetta P; Boutron-Ruault MC; Bracci PM; Brinton L; Brooks-Wilson AR; Bueno-De-Mesquita HB; Burdett L; Buring J; Butler MA; Cai Q; Cancel-Tassin G; Canzian F; Carrato A; Carreon T; Carta A; Chan JKC; Chang ET; Chang GC; Chang IS; Chang J; Chang-Claude J; Chen CJ; Chen CY; Chen C; Chen CH; Chen C; Chen H; Chen K; Chen KY; Chen KC; Chen Y; Chen YH; Chen YS; Chen YM; Chien LH; Chirlaque MD; Choi JE; Choi YY; Chow WH; Chung CC; Clavel J; Clavel-Chapelon F; Cocco P; Colt JS; Comperat E; Conde L; Connors JM; Conti D; Cortessis VK; Cotterchio M; Cozen W; Crouch S; Crous-Bou M; Cussenot O; Davis FG, 2015, 'Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types', Journal of the National Cancer Institute, vol. 107, http://dx.doi.org/10.1093/jnci/djv279
    Journal articles | 2015
    Professor David Thomas
    Mirabello L; Koster R; Moriarity BS; Spector LG; Meltzer PS; Gary J; Machiela MJ; Pankratz N; Panagiotou OA; Largaespada D; Wang Z; Gastier-Foster JM; Gorlick R; Khanna C; de Toledo SRC; Petrilli AS; Patiño-Garcia A; Sierrasesúmaga L; Lecanda F; Andrulis IL; Wunder JS; Gokgoz N; Serra M; Hattinger C; Picci P; Scotlandi K; Flanagan AM; Tirabosco R; Amary MF; Halai D; Ballinger ML; Thomas DM; Davis S; Barkauskas DA; Marina N; Helman L; Otto GM; Becklin KL; Wolf NK; Weg MT; Tucker M; Wacholder S; Fraumeni JF; Caporaso NE; Boland JF; Hicks BD; Vogt A; Burdett L; Yeager M; Hoover RN; Chanock SJ; Savage SA, 2015, 'A genome-wide scan identifies variants in NFIB associated with metastasis in patients with osteosarcoma', Cancer Discovery, vol. 5, pp. 920 - 931, http://dx.doi.org/10.1158/2159-8290.CD-15-0125
    Journal articles | 2015
    Professor David Thomas
    Chantrill LA; Nagrial AM; Watson C; Johns AL; Martyn-Smith M; Simpson S; Mead S; Jones MD; Samra JS; Gill AJ; Watson N; Chin VT; Humphris JL; Chou A; Brown B; Morey A; Pajic M; Grimmond SM; Chang DK; Thomas D; Sebastian L; Sjoquist K; Yip S; Pavlakis N; Asghari R; Harvey S; Grimison P; Simes J; Biankin AV, 2015, 'Precision medicine for advanced pancreas cancer: The individualized molecular pancreatic cancer therapy (IMPaCT) Trial', Clinical Cancer Research, vol. 21, pp. 2029 - 2037, http://dx.doi.org/10.1158/1078-0432.CCR-15-0426
    Journal articles | 2015
    Professor David Thomas
    Tattersall MHN; Thomas DM, 2015, 'Distinguishing activity from progress', The Lancet Oncology, vol. 16, pp. 1586 - 1588, http://dx.doi.org/10.1016/S1470-2045(15)00466-0
    Journal articles | 2015
    Professor David Thomas
    Neuhaus SJ; Thomas D; Desai J; Vuletich C; Von Dincklage J; Olver I, 2015, 'Wiki-based clinical practice guidelines for the management of adult onset sarcoma: A new paradigm in sarcoma evidence', Sarcoma, vol. 2015, http://dx.doi.org/10.1155/2015/614179
    Journal articles | 2015
    Professor David Thomas
    Parisot JP; Thorne H; Fellowes A; Doig K; Lucas M; McNeil JJ; Doble B; Dobrovic A; John T; James PA; Lipton L; Ashley D; Hayes T; McMurrick P; Richardson G; Lorgelly P; Fox SB; Thomas DM, 2015, '“Cancer 2015”: A prospective, population-based cancer cohort—phase 1: Feasibility of genomics-guided precision medicine in the clinic', Journal of Personalized Medicine, vol. 5, pp. 354 - 369, http://dx.doi.org/10.3390/jpm5040354
    Journal articles | 2015
    Professor David Thomas
    Ballinger ML; Mitchell G; Thomas DM, 2015, 'Surveillance recommendations for patients with germline TP53 mutations', Current Opinion in Oncology, vol. 27, pp. 332 - 337, http://dx.doi.org/10.1097/CCO.0000000000000200
    Journal articles | 2015
    Professor David Thomas
    Thomas DM; Fox S; Lorgelly PK; Ashley D; Richardson G; Lipton L; Parisot JP; Lucas M; McNeil J, 2015, 'Cancer 2015: A longitudinal whole-of-system study of genomic cancer medicine', Drug Discovery Today, vol. 20, pp. 1429 - 1432, http://dx.doi.org/10.1016/j.drudis.2015.10.009
    Journal articles | 2015
    Professor David Thomas
    Martin JH; Phillips E; Thomas D; Somogyi AA, 2015, 'Adding the 'medicines' back into personalized medicine to improve cancer treatment outcomes', British Journal of Clinical Pharmacology, vol. 80, pp. 929 - 931, http://dx.doi.org/10.1111/bcp.12690
    Journal articles | 2015
    Professor David Thomas
    Thomas DM; James PA; Ballinger ML, 2015, 'Clinical implications of genomics for cancer risk genetics', The Lancet Oncology, vol. 16, pp. e303 - e308, http://dx.doi.org/10.1016/S1470-2045(15)70026-4
    Journal articles | 2015
    Professor David Thomas
    Wong SQ; Fellowes A; Doig K; Ellul J; Bosma TJ; Irwin D; Vedururu R; Tan AYC; Weiss J; Chan KS; Lucas M; Thomas DM; Dobrovic A; Parisot JP; Fox SB, 2015, 'Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients', British Journal of Cancer, vol. 112, pp. 1411 - 1420, http://dx.doi.org/10.1038/bjc.2015.80
    Journal articles | 2015
    Professor David Thomas
    Ashley D; Thomas D; Gore L; Carter R; Zalcberg JR; Otmar R; Savulescu J, 2015, 'Accepting risk in the acceleration of drug development for rare cancers', The Lancet Oncology, vol. 16, pp. e190 - e194, http://dx.doi.org/10.1016/S1470-2045(14)71153-2
    Journal articles | 2015
    Professor David Thomas
    Thomas DM; Ballinger ML, 2015, 'Etiologic, environmental and inherited risk factors in sarcomas', Journal of Surgical Oncology, vol. 111, pp. 490 - 495, http://dx.doi.org/10.1002/jso.23809
    Journal articles | 2015
    Professor David Thomas
    Thomas DM, 2015, 'The growing problem of benign connective tissue tumours', The Lancet Oncology, vol. 16, pp. 879 - 880, http://dx.doi.org/10.1016/S1470-2045(15)00147-3
    Journal articles | 2015
    Professor David Thomas
    Papenfuss AT; Thomas DM, 2015, 'The life history of neochromosomes revealed', Molecular and Cellular Oncology, vol. 2, pp. e1000698, http://dx.doi.org/10.1080/23723556.2014.1000698
    Journal articles | 2014
    Professor David Thomas
    Garsed DW; Marshall OJ; Corbin VDA; Hsu A; DiStefano L; Schröder J; Li J; Feng ZP; Kim BW; Kowarsky M; Lansdell B; Brookwell R; Myklebost O; Meza-Zepeda L; Holloway AJ; Pedeutour F; Choo KHA; Damore MA; Deans AJ; Papenfuss AT; Thomas DM, 2014, 'The Architecture and Evolution of Cancer Neochromosomes', Cancer Cell, vol. 26, pp. 653 - 667, http://dx.doi.org/10.1016/j.ccell.2014.09.010
    Journal articles | 2014
    Professor David Thomas
    Kansara M; Teng MW; Smyth MJ; Thomas DM, 2014, 'Translational biology of osteosarcoma', Nature Reviews Cancer, vol. 14, pp. 722 - 735, http://dx.doi.org/10.1038/nrc3838
    Journal articles | 2014
    Professor David Thomas
    Wong SQ; Li J; Tan AYC; Vedururu R; Pang JMB; Do H; Ellul J; Doig K; Bell A; Macarthur GA; Fox SB; Thomas DM; Fellowes A; Parisot JP; Dobrovic A, 2014, 'Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing', BMC Medical Genomics, vol. 7, http://dx.doi.org/10.1186/1755-8794-7-23
    Journal articles | 2014
    Professor David Thomas
    McBride KA; Ballinger ML; Killick E; Kirk J; Tattersall MHN; Eeles RA; Thomas DM; Mitchell G, 2014, 'Li-Fraumeni syndrome: Cancer risk assessment and clinical management', Nature Reviews Clinical Oncology, vol. 11, pp. 260 - 271, http://dx.doi.org/10.1038/nrclinonc.2014.41
    Journal articles | 2014
    Professor David Thomas
    Kansara M; Thomas DM, 2014, 'RB1-mediated cell-autonomous and hostdependent oncosuppressor mechanisms in radiation-induced osteosarcoma', OncoImmunology, vol. 3, http://dx.doi.org/10.4161/onci.27569
    Journal articles | 2014
    Professor David Thomas
    Lewin J; Khamly KK; Young RJ; Mitchell C; Hicks RJ; Toner GC; Ngan SYK; Chander S; Powell GJ; Herschtal A; Te Marvelde L; Desai J; Choong PFM; Stacker SA; Achen MG; Ferris N; Fox S; Slavin J; Thomas DM, 2014, 'A phase Ib/II translational study of sunitinib with neoadjuvant radiotherapy in soft-tissue sarcoma', British Journal of Cancer, vol. 111, pp. 2254 - 2261, http://dx.doi.org/10.1038/bjc.2014.537
    Journal articles | 2014
    Professor David Thomas
    Pishas KI; Neuhaus SJ; Clayer MT; Schreiber AW; Lawrence DM; Perugini M; Whitfield RJ; Farshid G; Manavis J; Chryssidis S; Mayo BJ; Haycox RC; Ho K; Brown MP; D'Andrea RJ; Evdokiou A; Thomas DM; Desai J; Callen DF; Neilsen PM, 2014, 'Nutlin-3a efficacy in sarcoma predicted by transcriptomic and epigenetic profiling', Cancer Research, vol. 74, pp. 921 - 931, http://dx.doi.org/10.1158/0008-5472.CAN-13-2424
    Journal articles | 2014
    Professor David Thomas
    Wang Z; Zhu B; Zhang M; Parikh H; Jia J; Chung CC; Sampson JN; Hoskins JW; Hutchinson A; Burdette L; Ibrahim A; Hautman C; Raj PS; Abnet CC; Adjei AA; Ahlbom A; Albanes D; Allen NE; Ambrosone CB; Aldrich M; Amiano P; Amos C; Andersson U; Gerald Andriole GA; Andrulis IL; Arici C; Arslan AA; Austin MA; Baris D; Barkauskas DA; Bassig BA; Freeman LEB; Berg CD; Berndt SI; Bertazzi PA; Biritwum RB; Black A; Blot W; Boeing H; Boffetta P; Bolton K; Boutron-Ruault MC; Bracci PM; Brennan P; Brinton LA; Brotzman M; Bueno-de-Mesquita HB; Buring JE; Butler MA; Cai Q; Cancel-Tassin G; Canzian F; Cao G; Caporaso NE; Carrato A; Carreon T; Carta A; Chang GC; Chang IS; Chang-Claude J; Che X; Chen CJ; Chen CY; Chen CH; Chen C; Chen KY; Chen YM; Chokkalingam AP; Chu LW; Clavel-Chapelon F; Colditz GA; Colt JS; Conti D; Cook MB; Cortessis VK; Crawford ED; Cussenot O; Davis FG; De Vivo I; Deng X; Ding T; Dinney CP; Di Stefano AL; Diver WR; Duell EJ; Elena JW; Fan JH; Feigelson HS; Feychting M; Figueroa JD; Flanagan AM; Fraumeni JF; Freedman ND; Fridley BL; Fuchs CS; Gago-Dominguez M; Gallinger S; Gao YT; Gapstur SM; Garcia-Closas M, 2014, 'Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33', Human Molecular Genetics, vol. 23, pp. 6616 - 6633, http://dx.doi.org/10.1093/hmg/ddu363
    Journal articles | 2014
    Professor David Thomas
    Cipponi A; Thomas DM, 2014, 'Stress-induced cellular adaptive strategies: Ancient evolutionarily conserved programs as new anticancer therapeutic targets', BioEssays, vol. 36, pp. 552 - 560, http://dx.doi.org/10.1002/bies.201300170
    Journal articles | 2013
    Professor David Thomas
    Kansara M; Leong HS; Lin DM; Popkiss S; Pang P; Garsed DW; Walkley CR; Cullinane C; Ellul J; Haynes NM; Hicks R; Kuijjer ML; Cleton-Jansen AM; Hinds PW; Smyth MJ; Thomas DM, 2013, 'Immune response to rb1-Regulated senescence limits radiation-Induced osteosarcoma formation', Journal of Clinical Investigation, vol. 123, pp. 5351 - 5360, http://dx.doi.org/10.1172/JCI70559
    Journal articles | 2013
    Professor David Thomas
    Young M-A; Herlihy A; Mitchell G; Thomas DM; Ballinger M; Tucker K; Lewis CR; Neuhaus S; Halliday J, 2013, 'The attitudes of people with sarcoma and their family towards genomics and incidental information arising from genetic research', Clinical Sarcoma Research, vol. 3, pp. 11 - 11, http://dx.doi.org/10.1186/2045-3329-3-11
    Journal articles | 2013
    Professor David Thomas
    Harvey KF; Zhang X; Thomas DM, 2013, 'The Hippo pathway and human cancer', Nature Reviews Cancer, vol. 13, pp. 246 - 257, http://dx.doi.org/10.1038/nrc3458
    Journal articles | 2013
    Professor David Thomas
    Cain JE; McCaw A; Jayasekara WSN; Rossello FJ; Marini KD; Irving AT; Kansara M; Thomas DM; Ashley DM; Watkins DN, 2013, 'Sustained low-dose treatment with the Histone deacetylase inhibitor LBH589 induces terminal differentiation of osteosarcoma cells', Sarcoma, vol. 2013, http://dx.doi.org/10.1155/2013/608964
    Journal articles | 2013
    Professor David Thomas
    Collins M; Wilhelm M; Conyers R; Herschtal A; Whelan J; Bielack S; Kager L; Kühne T; Sydes M; Gelderblom H; Ferrari S; Picci P; Smeland S; Eriksson M; Petrilli AS; Bleyer A; Thomas DM, 2013, 'Benefits and adverse events in younger versus older patients receiving neoadjuvant chemotherapy for osteosarcoma: Findings from a meta-analysis', Journal of Clinical Oncology, vol. 31, pp. 2303 - 2312, http://dx.doi.org/10.1200/JCO.2012.43.8598
    Journal articles | 2013
    Professor David Thomas
    Chawla S; Henshaw R; Seeger L; Choy E; Blay JY; Ferrari S; Kroep J; Grimer R; Reichardt P; Rutkowski P; Schuetze S; Skubitz K; Staddon A; Thomas D; Qian Y; Jacobs I, 2013, 'Safety and efficacy of denosumab for adults and skeletally mature adolescents with giant cell tumour of bone: Interim analysis of an open-label, parallel-group, phase 2 study', The Lancet Oncology, vol. 14, pp. 901 - 908, http://dx.doi.org/10.1016/S1470-2045(13)70277-8
    Journal articles | 2013
    Professor David Thomas
    Tothill RW; Li J; Mileshkin L; Doig K; Siganakis T; Cowin P; Fellowes A; Semple T; Fox S; Byron K; Kowalczyk A; Thomas D; Schofield P; Bowtell DD, 2013, 'Massively-parallel sequencing assists the diagnosis and guided treatment of cancers of unknown primary', Journal of Pathology, vol. 231, pp. 413 - 423, http://dx.doi.org/10.1002/path.4251
    Journal articles | 2013
    Professor David Thomas
    Savage SA; Mirabello L; Wang Z; Gastier-Foster JM; Gorlick R; Khanna C; Flanagan AM; Tirabosco R; Andrulis IL; Wunder JS; Gokgoz N; Patiño-Garcia A; Sierrasesúmaga L; Lecanda F; Kurucu N; Ilhan IE; Sari N; Serra M; Hattinger C; Picci P; Spector LG; Barkauskas DA; Marina N; De Toledo SRC; Petrilli AS; Amary MF; Halai D; Thomas DM; Douglass C; Meltzer PS; Jacobs K; Chung CC; Berndt SI; Purdue MP; Caporaso NE; Tucker M; Rothman N; Landi MT; Silverman DT; Kraft P; Hunter DJ; Malats N; Kogevinas M; Wacholder S; Troisi R; Helman L; Fraumeni JF; Yeager M; Hoover RN; Chanock SJ, 2013, 'Genome-wide association study identifies two susceptibility loci for osteosarcoma', Nature Genetics, vol. 45, pp. 799 - 803, http://dx.doi.org/10.1038/ng.2645
    Journal articles | 2013
    Professor David Thomas
    Bandopadhayay P; Jabbour AM; Riffkin C; Salmanidis M; Gordon L; Popovski D; Rigby L; Ashley DM; Watkins DN; Thomas DM; Algar E; Ekert PG, 2013, 'The oncogenic properties of EWS/WT1 of desmoplastic small round cell tumors are unmasked by loss of p53 in murine embryonic fibroblasts', BMC Cancer, vol. 13, http://dx.doi.org/10.1186/1471-2407-13-585
    Journal articles | 2013
    Professor David Thomas
    Rossello FJ; Tothill RW; Britt K; Marini KD; Falzon J; Thomas DM; Peacock CD; Marchionni L; Li J; Bennett S; Tantoso E; Brown T; Chan P; Martelotto LG; Watkins DN, 2013, 'Next-Generation Sequence Analysis of Cancer Xenograft Models', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0074432
    Journal articles | 2013
    Professor David Thomas
    Lewin J; Puri A; Quek R; Ngan R; Alcasabas AP; Wood D; Thomas D, 2013, 'Management of sarcoma in the asia-pacific region: Resource-stratified guidelines', The Lancet Oncology, vol. 14, pp. e562 - e570, http://dx.doi.org/10.1016/S1470-2045(13)70475-3
    Journal articles | 2013
    Professor David Thomas
    Lewin J; Thomas D, 2013, 'Denosumab: A new treatment option for giant cell tumor of bone', Drugs of Today, vol. 49, pp. 693 - 700, http://dx.doi.org/10.1358/dot.2013.49.11.2064725
    Journal articles | 2013
    Professor David Thomas
    Mitchell G; Ballinger ML; Wong S; Hewitt C; James P; Young MA; Cipponi A; Pang T; Goode DL; Dobrovic A; Thomas DM; Porceddu S; Gattas M; Neuhaus S; Suthers G; Tattersall M; Tucker K; Lewis C; Carey-Smith R, 2013, 'High Frequency of Germline TP53 Mutations in a Prospective Adult-Onset Sarcoma Cohort', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0069026
    Journal articles | 2013
    Professor David Thomas
    Doble B; Harris A; Thomas DM; Fox S; Lorgelly P, 2013, 'Multiomics medicine in oncology: Assessing effectiveness, cost-effectiveness and future research priorities for the molecularly unique individual', Pharmacogenomics, vol. 14, pp. 1405 - 1417, http://dx.doi.org/10.2217/pgs.13.142
    Journal articles | 2012
    Professor David Thomas
    Thomas DM; Ballinger ML, 2012, 'Inherited and de novo germline TP53 mutations in adult-onset sarcoma', Hereditary cancer in clinical practice, vol. 10, pp. A26 - A26, http://dx.doi.org/10.1186/1897-4287-10-s2-a26
    Journal articles | 2012
    Professor David Thomas
    Mahendran K; Ballinger M; Kirk J; Thomas D; Tattersall M, 2012, 'Pathogenic germline TP53 mutations in adult sarcoma patients; implications for treatment and screening – description of an upcoming project', Hereditary cancer in clinical practice, vol. 10, pp. A61 - A61, http://dx.doi.org/10.1186/1897-4287-10-s2-a61
    Journal articles | 2012
    Professor David Thomas
    Pedeutour F; Maire G; Pierron A; Thomas DM; Garsed DW; Bianchini L; Duranton-Tanneur V; Cortes-Maurel A; Italiano A; Squire JA; Coindre JM, 2012, 'A newly characterized human well-differentiated liposarcoma cell line contains amplifications of the 12q12-21 and 10p11-14 regions', Virchows Archiv, vol. 461, pp. 67 - 78, http://dx.doi.org/10.1007/s00428-012-1256-5
    Journal articles | 2012
    Professor David Thomas
    Cassier PA; Gelderblom H; Stacchiotti S; Thomas D; Maki RG; Kroep JR; Van Der Graaf WT; Italiano A; Seddon B; Dômont J; Bompas E; Wagner AJ; Blay JY, 2012, 'Efficacy of imatinib mesylate for the treatment of locally advanced and/or metastatic tenosynovial giant cell tumor/pigmented villonodular synovitis', Cancer, vol. 118, pp. 1649 - 1655, http://dx.doi.org/10.1002/cncr.26409
    Journal articles | 2012
    Professor David Thomas
    Guagnano V; Kauffmann A; Wöhrle S; Stamm C; Ito M; Barys L; Pornon A; Yao Y; Li F; Zhang Y; Chen Z; Wilson CJ; Bordas V; Le Douget M; Alex Gaither L; Borawski J; Monahan JE; Venkatesan K; Brümmendorf T; Thomas DM; Garcia-Echeverria C; Hofmann F; Sellers WR; Graus-Porta D, 2012, 'FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a selective Pan-FGFR inhibitor', Cancer Discovery, vol. 2, pp. 1118 - 1133, http://dx.doi.org/10.1158/2159-8290.CD-12-0210
    Journal articles | 2012
    Professor David Thomas
    Paget C; Duret H; Ngiow SF; Kansara M; Thomas DM; Smyth MJ, 2012, 'Studying the role of the immune system on the antitumor activity of a Hedgehog inhibitor against murine osteosarcoma', OncoImmunology, vol. 1, pp. 1313 - 1322, http://dx.doi.org/10.4161/onci.21680
    Journal articles | 2012
    Professor David Thomas
    Branstetter DG; Nelson SD; Manivel JC; Blay JY; Chawla S; Thomas DM; Jun S; Jacobs I, 2012, 'Denosumab induces tumor reduction and bone formation in patients with giant-cell tumor of bone', Clinical Cancer Research, vol. 18, pp. 4415 - 4424, http://dx.doi.org/10.1158/1078-0432.CCR-12-0578
    Journal articles | 2012
    Professor David Thomas
    Dyson GJ; Thompson K; Palmer S; Thomas DM; Schofield P, 2012, 'The relationship between unmet needs and distress amongst young people with cancer', Supportive Care in Cancer, vol. 20, pp. 75 - 85, http://dx.doi.org/10.1007/s00520-010-1059-7
    Journal articles | 2012
    Professor David Thomas
    Kelleher FC; Cain JE; Healy JM; Watkins DN; Thomas DM, 2012, 'Prevailing importance of the hedgehog signaling pathway and the potential for treatment advancement in sarcoma', Pharmacology and Therapeutics, vol. 136, pp. 153 - 168, http://dx.doi.org/10.1016/j.pharmthera.2012.08.004
    Journal articles | 2012
    Professor David Thomas
    Thomas DM, 2012, 'RANKL, denosumab, and giant cell tumor of bone', Current Opinion in Oncology, vol. 24, pp. 397 - 403, http://dx.doi.org/10.1097/CCO.0b013e328354c129
    Journal articles | 2012
    Professor David Thomas
    Hubbard J; Thomas DM; Yothers G; Green E; Blanke C; O'Connell MJ; Labianca R; Shi Q; Bleyer A; De Gramont A; Sargent D, 2012, 'Benefits and adverse events in younger versus older patients receiving adjuvant chemotherapy for colon cancer: Findings from the adjuvant colon cancer endpoints data set', Journal of Clinical Oncology, vol. 30, pp. 2334 - 2339, http://dx.doi.org/10.1200/JCO.2011.41.1975
    Journal articles | 2012
    Professor David Thomas
    Ray-Coquard I; Thomas D, 2012, 'Targeted therapies: Pazopanib for soft-tissue sarcoma: A PALETTE of data emerges', Nature Reviews Clinical Oncology, vol. 9, pp. 431 - 432, http://dx.doi.org/10.1038/nrclinonc.2012.113
    Journal articles | 2011
    Professor David Thomas
    Ito M; Barys L; O'Reilly T; Young S; Gorbatcheva B; Monahan J; Zumstein-Mecker S; Choong PF; Dickinson I; Crowe P; Hemmings C; Desai J; Thomas DM; Lisztwan J, 2011, 'Comprehensive mapping of p53 pathway alterations reveals an apparent role for both SNP309 and MDM2 amplification in sarcomagenesis', Clinical Cancer Research, vol. 17, pp. 416 - 426, http://dx.doi.org/10.1158/1078-0432.CCR-10-2050
    Journal articles | 2011
    Professor David Thomas
    Blanke CD; Bot BM; Thomas DM; Bleyer A; Kohne CH; Seymour MT; De Gramont A; Goldberg RM; Sargent DJ, 2011, 'Impact of young age on treatment efficacy and safety in advanced colorectal cancer: A pooled analysis of patients from nine first-line phase III chemotherapy trials', Journal of Clinical Oncology, vol. 29, pp. 2781 - 2786, http://dx.doi.org/10.1200/JCO.2010.33.5281
    Journal articles | 2011
    Professor David Thomas
    Hemmings C; Miles C; Slavin J; Bonar SF; Graf N; Austen L; Thomas D; Desai J; Barry P, 2011, 'Optimising the management of soft tissue tumours', Pathology, vol. 43, pp. 295 - 301, http://dx.doi.org/10.1097/PAT.0b013e3283464427
    Journal articles | 2011
    Professor David Thomas
    Clark JCM; Akiyama T; Thomas DM; Labrinidis A; Evdokiou A; Galloway SJ; Kim HS; Dass CR; Choong PFM, 2011, 'RECK in osteosarcoma: A novel role in tumour vasculature and inhibition of tumorigenesis in an orthotopic model', Cancer, vol. 117, pp. 3517 - 3528, http://dx.doi.org/10.1002/cncr.25757
    Journal articles | 2011
    Professor David Thomas
    Aubin S; Barr R; Rogers P; Schacter B; Bielack SS; Ferrari A; Manchester RA; McMaster K; Morgan S; Patterson M; Petrilli AS; Ribera J-M; Shaw P; Thomas DM; Treadgold C, 2011, 'What Should the Age Range Be for AYA Oncology?', JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY, vol. 1, pp. 3 - 10, http://dx.doi.org/10.1089/jayao.2011.1505
    Journal articles | 2011
    Professor David Thomas
    Thomas D; Moore A, 2011, 'Counterpoints in cancer: The somatic mutation theory under attack', BioEssays, vol. 33, pp. 313 - 314, http://dx.doi.org/10.1002/bies.201190016
    Journal articles | 2011
    Professor David Thomas
    Newnham GM; Conron M; McLachlan SA; Dobrovic A; Do H; Li J; Opeskin K; Thompson N; Wright GM; Thomas DM, 2011, 'Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer', BMC Cancer, vol. 11, http://dx.doi.org/10.1186/1471-2407-11-93
    Journal articles | 2011
    Professor David Thomas
    Collins IM; Thomas DM, 2011, 'Novel approaches to treatment of leiomyosarcomas', Current Oncology Reports, vol. 13, pp. 316 - 322, http://dx.doi.org/10.1007/s11912-011-0173-0
    Journal articles | 2011
    Professor David Thomas
    Lockwood WW; Stack D; Morris T; Grehan D; O'Keane C; Stewart GL; Cumiskey J; Lam WL; Squire JA; Thomas DM; O'Sullivan MJ, 2011, 'Cyclin E1 is amplified and overexpressed in osteosarcoma', Journal of Molecular Diagnostics, vol. 13, pp. 289 - 296, http://dx.doi.org/10.1016/j.jmoldx.2010.11.020
    Journal articles | 2011
    Professor David Thomas
    Thomas DM; Conyers R; Young S, 2011, 'Liposarcoma: Molecular genetics and therapeutics', Sarcoma, vol. 2011, http://dx.doi.org/10.1155/2011/483154
    Journal articles | 2011
    Professor David Thomas
    Neilsen PM; Pishas KI; Callen DF; Thomas DM, 2011, 'Targeting the p53 pathway in Ewing Sarcoma', Sarcoma, vol. 2011, http://dx.doi.org/10.1155/2011/746939
    Journal articles | 2011
    Professor David Thomas
    Thomas DM, 2011, 'Lessons from the deep study of rare tumours', Journal of Pathology, vol. 224, pp. 306 - 308, http://dx.doi.org/10.1002/path.2928
    Journal articles | 2010
    Professor David Thomas
    Ferrari A; Thomas D; Franklin ARK; Hayes-Lattin BM; Mascarin M; Van Der Graaf W; Albritton KH, 2010, 'Starting an Adolescent and Young Adult Program: Some success stories and some obstacles to overcome', Journal of Clinical Oncology, vol. 28, pp. 4850 - 4857, http://dx.doi.org/10.1200/JCO.2009.23.8097
    Journal articles | 2010
    Professor David Thomas
    Thomas D; Henshaw R; Skubitz K; Chawla S; Staddon A; Blay JY; Roudier M; Smith J; Ye Z; Sohn W; Dansey R; Jun S, 2010, 'Denosumab in patients with giant-cell tumour of bone: an open-label, phase 2 study', The Lancet Oncology, vol. 11, pp. 275 - 280, http://dx.doi.org/10.1016/S1470-2045(10)70010-3
    Journal articles | 2010
    Professor David Thomas
    Thomas DM, 2010, 'Wnts, bone and cancer', Journal of Pathology, vol. 220, pp. 1 - 4, http://dx.doi.org/10.1002/path.2635
    Journal articles | 2010
    Professor David Thomas
    Thomas DM; Albritton KH; Ferrari A, 2010, 'Adolescent and young adult oncology: An emerging field', Journal of Clinical Oncology, vol. 28, pp. 4781 - 4782, http://dx.doi.org/10.1200/JCO.2010.30.5128
    Journal articles | 2010
    Professor David Thomas
    Thomas DM; Wagner AJ, 2010, 'Specific targets in sarcoma and developmental therapeutics', JNCCN Journal of the National Comprehensive Cancer Network, vol. 8, pp. 677 - 685, http://dx.doi.org/10.6004/jnccn.2010.0050
    Journal articles | 2010
    Professor David Thomas
    Thomas D; Carriere P; Jacobs I, 2010, 'Safety of denosumab in giant-cell tumour of bone', The Lancet Oncology, vol. 11, pp. 815, http://dx.doi.org/10.1016/S1470-2045(10)70170-4
    Journal articles | 2010
    Professor David Thomas
    Thomas D, 2010, 'The hard and soft sides of cancer programming', BioEssays, vol. 32, pp. 837 - 838, http://dx.doi.org/10.1002/bies.201090036
    Journal articles | 2010
    Professor David Thomas
    Thomas DM, 2010, 'Importance of molecular genetics of sarcomas', Cancer Forum, vol. 34, pp. 154 - 156
    Journal articles | 2009
    Professor David Thomas
    Kansara M; Tsang M; Kodjabachian L; Sims NA; Trivett MK; Ehrich M; Dobrovic A; Slavin J; Choong PFM; Simmons PJ; Dawid IB; Thomas DM, 2009, 'Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice', Journal of Clinical Investigation, vol. 119, pp. 837 - 851, http://dx.doi.org/10.1172/JCI37175
    Journal articles | 2009
    Professor David Thomas
    Fleming NI; Trivett MK; George J; Slavin JL; Murray WK; Moseley JM; Anderson RL; Thomas DM, 2009, 'Parathyroid hormone-related protein protects against mammary tumor emergence and is associated with monocyte infiltration in ductal carcinoma in situ', Cancer Research, vol. 69, pp. 7473 - 7479, http://dx.doi.org/10.1158/0008-5472.CAN-09-0194
    Journal articles | 2009
    Professor David Thomas
    Garsed DW; Holloway AJ; Thomas DM, 2009, 'Cancer-associated neochromosomes: A novel mechanism of oncogenesis', BioEssays, vol. 31, pp. 1191 - 1200, http://dx.doi.org/10.1002/bies.200800208
    Journal articles | 2009
    Professor David Thomas
    Fleming NI; Trivett MK; George J; Slavin JL; Murray WK; Moseley JM; Anderson RL; Thomas DM, 2009, 'Parathyroid hormone-related protein protects against mammary tumor emergence and is associated with monocyte infiltration in ductal carcinoma in situ (Cancer Research (2009) 69, (7473-7479))', Cancer Research, vol. 69, pp. 8832, http://dx.doi.org/10.1158/0008-5472.CAN-09-3870
    Journal articles | 2009
    Professor David Thomas
    Khamly KK; Thursfield VJ; Fay M; Desai J; Toner GC; Choong PFM; Ngan SYK; Powell GJ; Thomas DM, 2009, 'Gender-specific activity of chemotherapy correlates with outcomes in chemosensitive cancers of young adulthood', International Journal of Cancer, vol. 125, pp. 426 - 431, http://dx.doi.org/10.1002/ijc.24376
    Journal articles | 2009
    Professor David Thomas
    Thomas DM; Skubitz KM, 2009, 'Giant cell tumour of bone', Current Opinion in Oncology, vol. 21, pp. 338 - 344, http://dx.doi.org/10.1097/CCO.0b013e32832c951d
    Journal articles | 2009
    Professor David Thomas
    Pires de Camargo V; van de Rijn M; de Alava E; Madoz-Gúrpide J; Pilotti S; von Mehren M; Pedeutour F; Maki RG; Rutkowski P; Thomas DM, 2009, 'Other Targetable Sarcomas', Seminars in Oncology, vol. 36, pp. 358 - 371, http://dx.doi.org/10.1053/j.seminoncol.2009.06.008
    Journal articles | 2009
    Professor David Thomas
    Thomas DM; O'Sullivan B; Gronchi A, 2009, 'Current concepts and future perspectives in retroperitoneal soft-tissue sarcoma management', Expert Review of Anticancer Therapy, vol. 9, pp. 1145 - 1157, http://dx.doi.org/10.1586/ERA.09.77
    Journal articles | 2009
    Professor David Thomas
    Soliman H; Ferrari A; Thomas D, 2009, 'Sarcoma in the Young Adult Population: An International View', Seminars in Oncology, vol. 36, pp. 227 - 236, http://dx.doi.org/10.1053/j.seminoncol.2009.03.006
    Journal articles | 2009
    Professor David Thomas
    Thomas D; Whyte S; Choong P, 2009, 'Australian Sarcona Study Group: Development and outlook', Cancer Forum, vol. 33, pp. 25 - 28
    Journal articles | 2008
    Professor David Thomas
    Bleyer A; Barr R; Hayes-Lattin B; Thomas D; Ellis C; Anderson B, 2008, 'The distinctive biology of cancer in adolescents and young adults', Nature Reviews Cancer, vol. 8, pp. 288 - 298, http://dx.doi.org/10.1038/nrc2349
    Journal articles | 2008
    Professor David Thomas
    Gutierrez GM; Kong E; Sabbagh Y; Brown NE; Lee JS; Demay MB; Thomas DM; Hinds PW, 2008, 'Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice', Proceedings of the National Academy of Sciences of the United States of America, vol. 105, pp. 18402 - 18407, http://dx.doi.org/10.1073/pnas.0805925105
    Journal articles | 2008
    Professor David Thomas
    Alvaro F; Young A; Goldstein D; Thomas D; McJannett M; Dillon R, 2008, 'Clinical oncological society of Australia: Adolescent and young adult cancer forum', Cancer Forum, vol. 32, pp. 116 - 119
    Journal articles | 2008
    Professor David Thomas
    Khamly KK; Hicks RJ; McArthur GA; Thomas DM, 2008, 'The promise of PET in clinical management and as a sensitive test for drug cytotoxicity in sarcomas', Expert Review of Molecular Diagnostics, vol. 8, pp. 105 - 119, http://dx.doi.org/10.1586/14737159.8.1.105
    Journal articles | 2008
    Professor David Thomas
    Newnham GM; Thomas DM; McLachlan SA; Wright G; Conron M, 2008, 'Molecular Profiling of Non-Small Cell Lung Cancer: Of What Value in Clinical Practice?', Heart Lung and Circulation, vol. 17, pp. 451 - 462, http://dx.doi.org/10.1016/j.hlc.2007.11.144
    Journal articles | 2007
    Professor David Thomas
    Kansara M; Thomas DM, 2007, 'Molecular pathogenesis of osteosarcoma', DNA and Cell Biology, vol. 26, pp. 1 - 18, http://dx.doi.org/10.1089/dna.2006.0505
    Journal articles | 2007
    Professor David Thomas
    Clark JCM; Thomas DM; Choong PFM; Dass CR, 2007, 'RECK - A newly discovered inhibitor of metastasis with prognostic significance in multiple forms of cancer', Cancer and Metastasis Reviews, vol. 26, pp. 675 - 683, http://dx.doi.org/10.1007/s10555-007-9093-8
    Journal articles | 2007
    Professor David Thomas
    Fon A; Mileshkin L; Slavin J; Twomey H; James P; Thomas DM, 2007, 'Synchronous diagnosis of Hodgkin lymphoma and osteosarcoma [1]', Internal Medicine Journal, vol. 37, pp. 731 - 732, http://dx.doi.org/10.1111/j.1445-5994.2007.01465.x
    Journal articles | 2007
    Professor David Thomas
    Thomas DM, 2007, 'Adolescents and young adults with cancer: The challenge', Palliative and Supportive Care, vol. 5, pp. 173 - 174, http://dx.doi.org/10.1017/S1478951507070253
    Journal articles | 2006
    Professor David Thomas
    Thomas DM; Seymour JF; O'Brien T; Sawyer SM; Ashley DM, 2006, 'Adolescent and young adult cancer: A revolution in evolution?', Internal Medicine Journal, vol. 36, pp. 302 - 307, http://dx.doi.org/10.1111/j.1445-5994.2006.01062.x
    Journal articles | 2006
    Professor David Thomas
    Thomas D; Kansara M, 2006, 'Epigenetic modifications in osteogenic differentiation and transformation', Journal of Cellular Biochemistry, vol. 98, pp. 757 - 769, http://dx.doi.org/10.1002/jcb.20850
    Journal articles | 2006
    Professor David Thomas
    Tan JZY; Schlicht SM; Powell GJ; Thomas D; Slavin JL; Smith PJ; Choong PFM, 2006, 'Multidisciplinary approach to diagnosis and management of osteosarcoma - A review of the St Vincent's Hospital experience', International Seminars in Surgical Oncology, vol. 3, http://dx.doi.org/10.1186/1477-7800-3-38
    Journal articles | 2006
    Professor David Thomas
    Krypuy M; Newnham GM; Thomas DM; Conron M; Dobrovic A, 2006, 'High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer', BMC Cancer, vol. 6, http://dx.doi.org/10.1186/1471-2407-6-295
    Journal articles | 2006
    Professor David Thomas
    Chaffer CL; Thomas DM; Thompson EW; Williams ED, 2006, 'PPARγ-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma', BMC Cancer, vol. 6, http://dx.doi.org/10.1186/1471-2407-6-53
    Journal articles | 2006
    Professor David Thomas
    Lee JS; Thomas DM; Gutierrez G; Carty SA; Yanagawa SI; Hinds PW, 2006, 'HES1 cooperates with pRb to activate RUNX2-dependent transcription', Journal of Bone and Mineral Research, vol. 21, pp. 921 - 933, http://dx.doi.org/10.1359/jbmr.060303
    Journal articles | 2006
    Professor David Thomas
    Amukotuwa SA; Choong PFM; Smith PJ; Powell GJ; Thomas D; Schlicht SM, 2006, 'Femoral mesenchymal chondrosarcoma with secondary aneurysmal bone cysts mimicking a small-cell osteosarcoma', Skeletal Radiology, vol. 35, pp. 311 - 318, http://dx.doi.org/10.1007/s00256-005-0044-6
    Journal articles | 2006
    Professor David Thomas
    Slavin JL; Thomas D, 2006, 'Gene expression profiling of sarcomas', Pathology, vol. 38, pp. 101 - 102, http://dx.doi.org/10.1080/00313020600595854
    Journal articles | 2005
    Professor David Thomas
    Cullinane C; Dorow DS; Kansara M; Conus N; Binns D; Hicks RJ; Ashman LK; McArthur GA; Thomas DM, 2005, 'An in vivo tumor model exploiting metabolic response as a biomarker for targeted drug development', Cancer Research, vol. 65, pp. 9633 - 9636, http://dx.doi.org/10.1158/0008-5472.CAN-05-2285
    Journal articles | 2005
    Professor David Thomas
    Morgan T; Atkins GJ; Trivett MK; Johnson SA; Kansara M; Schlicht SL; Slavin JL; Simmons P; Dickinson I; Powell G; Choong PFM; Holloway AJ; Thomas DM, 2005, 'Molecular profiling of giant cell tumor of bone and the osteoclastic localization of ligand for receptor activator of nuclear factor κB', American Journal of Pathology, vol. 167, pp. 117 - 128, http://dx.doi.org/10.1016/S0002-9440(10)62959-8
    Journal articles | 2005
    Professor David Thomas
    Dudley AC; Thomas D; Best J; Jenkins A, 2005, 'A VEGF/JAK2/STAT5 axis may partially mediate endothelial cell tolerance to hypoxia', Biochemical Journal, vol. 390, pp. 427 - 436, http://dx.doi.org/10.1042/BJ20050351
    Journal articles | 2004
    Professor David Thomas
    Thomas DM; Johnson SA; Sims NA; Trivett MK; Slavin JL; Rubin BP; Waring P; McArthur GA; Walkley CR; Holloway AJ; Diyagama D; Grim JE; Clurman BE; Bowtell DDL; Lee JS; Gutierrez GM; Piscopo DM; Carty SA; Hinds PW, 2004, 'Terminal osteoblast differentiation, mediated by runx2 and p27 KIP1, is disrupted in osteosarcoma', Journal of Cell Biology, vol. 167, pp. 925 - 934, http://dx.doi.org/10.1083/jcb.200409187
    Journal articles | 2004
    Professor David Thomas
    Thomas DM; Fleming NI; Holloway AJ; Bowtell DDL, 2004, 'Molecular medicine: A clinician's primer on microarrays', Internal Medicine Journal, vol. 34, pp. 565 - 569, http://dx.doi.org/10.1111/j.1445-5994.2004.00680.x
    Journal articles | 2004
    Professor David Thomas
    Dudley AC; Thomas D; Best J; Jenkins A, 2004, 'The STATs in cell stress-type responses', Cell Communication and Signaling, vol. 2, http://dx.doi.org/10.1186/1478-811X-2-8
    Journal articles | 2003
    Professor David Thomas
    Dudley A; Gilbert RE; Thomas D; Cox A; Price JT; Best J; Jenkins A, 2003, 'STI-571 inhibits in vitro angiogenesis', Biochemical and Biophysical Research Communications, vol. 310, pp. 135 - 142, http://dx.doi.org/10.1016/j.bbrc.2003.08.129
    Journal articles | 2003
    Professor David Thomas
    Thomas DM; Yang HS; Alexander K; Hinds PW, 2003, 'Role of the retinoblastoma protein in differentiation and senescence', Cancer Biology and Therapy, vol. 2, pp. 124 - 130, http://dx.doi.org/10.4161/cbt.2.2.235
    Journal articles | 2003
    Professor David Thomas
    Dudley A; McKinstry W; Thomas D; Best J; Jenkins A, 2003, 'Removal of endotoxin by reverse phase HPLC abolishes anti-endothelial cell activity of bacterially expressed plasminogen kringle 5', BioTechniques, vol. 35, pp. 724 - 732, http://dx.doi.org/10.2144/03354st02
    Journal articles | 2003
    Professor David Thomas
    Chin SL; Johnson SA; Quinn J; Mirosavljevic D; Price JT; Dudley AC; Thomas DM, 2003, 'A role for αV integrin subunit in TGF-β-stimulated osteoclastogenesis', Biochemical and Biophysical Research Communications, vol. 307, pp. 1051 - 1058, http://dx.doi.org/10.1016/S0006-291X(03)01294-4
    Journal articles | 2002
    Professor David Thomas
    Cook N; Thomas DM, 2002, 'Retrospective survey of unselected hospital patients with and without cancer comparing outcomes following venous thromboembolism', Internal Medicine Journal, vol. 32, pp. 437 - 444, http://dx.doi.org/10.1046/j.1445-5994.2002.00249.x
    Journal articles | 2001
    Professor David Thomas
    Rosenthal MA; Thomas D; Davis I; Toner G; Noordin N; Zalcberg J, 2001, 'Pilot study of oral eniluracil/5-FU in the palliation of hormone-refractory prostate cancer', Prostate Journal, vol. 3, pp. 30 - 35, http://dx.doi.org/10.1046/j.1525-1411.2001.003001030.x
    Journal articles | 2001
    Professor David Thomas
    Thomas DM; Carty SA; Piscopo DM; Lee JS; Wang WF; Forrester WC; Hinds PW, 2001, 'The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation', Molecular Cell, vol. 8, pp. 303 - 316, http://dx.doi.org/10.1016/S1097-2765(01)00327-6
    Journal articles | 1999
    Professor David Thomas
    Ebeling PR; Thomas DM; Erbas B; Hopper JL; Szer J; Grigg AP, 1999, 'Mechanisms of bone loss following allogeneic and autologous hemopoietic stem cell transplantation', Journal of Bone and Mineral Research, vol. 14, pp. 342 - 350, http://dx.doi.org/10.1359/jbmr.1999.14.3.342
    Journal articles | 1999
    Professor David Thomas
    Puche RC; Thomas DM; Udagawa N; Hards DK; Quinn JMW; Moseley JM; Findlay DM; Best JD, 1999, 'Letters to the editor (multiple letters).', Bone, vol. 25
    Journal articles | 1998
    Professor David Thomas
    Thomas DM; Zalcberg JR, 1998, '5-Fluorouracil: A pharmacological paradigm in the use of cytotoxics', Clinical and Experimental Pharmacology and Physiology, vol. 25, pp. 887 - 895, http://dx.doi.org/10.1111/j.1440-1681.1998.tb02339.x
    Journal articles | 1998
    Professor David Thomas
    Thomas DM; Mitchell PLR; Berlangieri SU; Tochon-Danguy H; Knight S; Clarke CP; Scott AM, 1998, 'Positron emission tomography in assessing response to neoadjuvant chemotherapy for non-small-cell lung cancer [1]', Medical Journal of Australia, vol. 169, pp. 227, http://dx.doi.org/10.5694/j.1326-5377.1998.tb140229.x
    Journal articles | 1998
    Professor David Thomas
    Thomas DM; Seymour JF; Szer J; Grigg AP; Basser RL; Green MD; Fox RM; Thomas DM, 1998, 'Progress in management of acute myeloid leukaemia (AML) in Australia since 1980: A single institution retrospective study', Australian and New Zealand Journal of Medicine, vol. 28, pp. 190 - 196, http://dx.doi.org/10.1111/j.1445-5994.1998.tb02968.x
    Journal articles | 1998
    Professor David Thomas
    Thomas DM; Udagawa N; Hards DK; Quinn JMW; Moseley JM; Findlay DM; Best JD, 1998, 'Insulin receptor expression in primary and cultured osteoclast-like cells', Bone, vol. 23, pp. 181 - 186, http://dx.doi.org/10.1016/S8756-3282(98)00095-7
    Journal articles | 1998
    Professor David Thomas
    Thomas DM; Mitchell PLR; Berlangieri SU; Tochon-Danguy H; Knight S; Clarke CP; Scott AM, 1998, 'Positron emission tomography in assessing response to neoadjuvant chemotherapy for non-small-cell lung cancer (vol 169, pg 227, 1998)', MEDICAL JOURNAL OF AUSTRALIA, vol. 169, pp. 344 - 344, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000076023200028&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1998
    Professor David Thomas
    Thomas DM; Mitchell PLR; Berlangieri SU; Tochon-Danguy H; Knight S; Clarke CP; Scott AM, 1998, 'Correction: Positron emission tomography in assessing response to neoadjuvant chemotherapy for non-small-cell lung cancer (Medical Journal of Australia (1998) 169 (227))', Medical Journal of Australia, vol. 169, pp. 344
    Journal articles | 1997
    Professor David Thomas
    Thomas DM; Seymour JF; Griffiths JD; Szer J; Grigg AP, 1997, 'Prolonged disease-free survival with specific re-induction therapy in acute myeloid leukaemia relapsing following bone marrow transplantation', Australian and New Zealand Journal of Medicine, vol. 27, pp. 712 - 713, http://dx.doi.org/10.1111/j.1445-5994.1997.tb01009.x
    Journal articles | 1997
    Professor David Thomas
    Thomas DM; Ng KW; Best JD, 1997, 'Insulin and bone: A clinical and scientific review', Endocrinology and Metabolism, Supplement, vol. 4, pp. 5 - 17
    Journal articles | 1996
    Professor David Thomas
    Thomas DM; Hards DK; Rogers SD; Ng KW; Best JD, 1996, 'Insulin receptor expression in bone', Journal of Bone and Mineral Research, vol. 11, pp. 1312 - 1320, http://dx.doi.org/10.1002/jbmr.5650110916
    Journal articles | 1996
    Professor David Thomas
    Thomas DM; Maher F; Rogers SD; Best JD, 1996, 'Expression and regulation by insulin of Glut 3 in UMR 106-01, a clonal rat osteosarcoma cell line', Biochemical and Biophysical Research Communications, vol. 218, pp. 789 - 793, http://dx.doi.org/10.1006/bbrc.1996.0140
    Journal articles | 1996
    Professor David Thomas
    Thomas DM; Rogers SD; Ng KW; Best JD, 1996, 'Dexamethasone modulates insulin receptor expression and subcellular distribution of the glucose transporter GLUT 1 in UMR 106-01, a clonal osteogenic sarcoma cell line', Journal of Molecular Endocrinology, vol. 17, pp. 7 - 17, http://dx.doi.org/10.1677/jme.0.0170007
    Journal articles | 1995
    Professor David Thomas
    Thomas DM; Rogers SD; Sleeman MW; Pasquini GM; Bringhurst FR; Ng KW; Zajac JD; Best JD, 1995, 'Modulation of glucose transport by parathyroid hormone and insulin in UMR 106-01, a clonal rat osteogenic sarcoma cell line', Journal of Molecular Endocrinology, vol. 14, pp. 263 - 275, http://dx.doi.org/10.1677/jme.0.0140263
    Journal articles |
    Professor David Thomas
    Lin FP; Thavaneswaran S; Grady JP; Ballinger M; Kansara M; Oakes SR; Desai J; Lee CK; Simes J; Thomas DM, 'Criteria-based curation of a therapy-focused compendium to support treatment recommendations in precision oncology', , http://dx.doi.org/10.1101/2020.12.18.20248521
  • Conference Abstracts | 2020
    Professor David Thomas
    Best M; Butow P; Jacobs C; Juraskova I; Savard J; Meiser B; Goldstein D; Ballinger M; Bartley N; Napier C; Davies G; Thomas D; Tucker K; Schlub T; Newson AJ, 2020, 'Advanced cancer patient preferences for receiving molecular profiling results', in Psycho-Oncology, WILEY, Vol. 29, pp. 1533 - 1539, http://dx.doi.org/10.1002/pon.5446
    Conference Papers | 2019
    Professor David Thomas
    Shin SJ; Dodd E; Peng G; Bojadzieva J; Chen J; Ning J; Mai PL; Savage SA; Ballinger ML; Thomas DM; Yuan Y; Strong LC; Wang W, 2019, 'Abstract 2434: Characterizing age-of-onset of multiple primary cancers and specific cancer types in families with Li-Fraumeni syndrome', in Prevention, Early Detection, and Interception, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-2434
    Conference Papers | 2019
    Professor David Thomas
    Ballinger ML; Pinese M; Thomas DM, 2019, 'Translating genomic risk into an early detection strategy for sarcoma', in Genes Chromosomes and Cancer, United States, pp. 130 - 136, United States, http://dx.doi.org/10.1002/gcc.22697
    Conference Abstracts | 2019
    Professor David Thomas
    Thavaneswaran S; Ballinger ML; Grady J; Cowley M; Joshua A; Sebastian L; Collignon E; Silvestri A; Kansara M; Pinese M; Sjoquist KM; Hague W; Lee CK; Simes J; Thomas DM, 2019, 'The Cancer Molecular Screening and Therapeutics Program (MoST): Actionable mutation frequencies in a population with rare and less common cancers.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, Chicago, IL, Vol. 37, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL, 31 May 2019 - 04 June 2019, http://dx.doi.org/10.1200/JCO.2019.37.15_suppl.3136
    Conference Abstracts | 2019
    Professor David Thomas
    Thavaneswaran S; Napier C; Goldstein D; Meiser B; Butow P; Thomas DM; Ballinger ML; Best M, 2019, 'Medical oncologists' experience with returning molecular tumor profiling to patients.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, Chicago, IL, Vol. 37, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL, 31 May 2019 - 04 June 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000487345804031&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2018
    Professor David Thomas
    Pinese M; Ballinger M; Thomas D, 2018, 'Abstract IA03: Translating genomic risk into an early detection strategy for sarcoma', in Genomics, American Association for Cancer Research, presented at Abstracts: Advances in Sarcomas: From Basic Science to Clinical Translation; May 16-19, 2017; Philadelphia, PA, http://dx.doi.org/10.1158/1557-3265.sarcomas17-ia03
    Conference Abstracts | 2018
    Professor David Thomas
    Barnet M; Jackson K; Gao B; Nagrial A; Boyer M; Cooper W; Hui R; Linton A; Tattersall M; Russell A; Gibson G; Cebon J; Long G; Menzies A; Scolyer R; Lacaze P; Brink R; Peters T; Cowley M; Gayevskiy V; Thomas D; Pinese M; Blinman P; Kao S; Goodnow C, 2018, 'Exploring the Germ-Line Contribution to Exceptional Response to PD-1/PD-L1 Inhibition in Patients with NSCLC by Whole Genome Sequencing', in JOURNAL OF THORACIC ONCOLOGY, ELSEVIER SCIENCE INC, Vol. 13, pp. S529 - S529, http://dx.doi.org/10.1016/j.jtho.2018.08.726
    Conference Papers | 2018
    Professor David Thomas
    Barnet MB; Jackson KJ; Gao B; Nagrial AM; Boyer MJ; Cooper WA; Hui R; Linton A; Tattersall MH; Gibson G; Cebon J; Long GV; Menzies AM; Scolyer RA; Lacaze P; Brink R; Peters T; Cowley M; Gayevskiy V; Thomas DM; Pinese M; Blinman P; Kao S; Goodnow CC, 2018, 'Exploring the germ-line contribution to exceptional response to PD-1/PD-L1 inhibition in patients with metastatic non-small-cell lung cancer by whole genome sequencing', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Chicago, IL, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Chicago, IL, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-LB-121
    Conference Papers | 2018
    Professor David Thomas
    Kansara M; Pang P; Sulkowski N; Teng M; Smyth M; Thomas D, 2018, 'Abstract PR13: Pivotal role of interleukin 23 in osteosarcoma development and its link with glutamate metabotropic 4: Identification of novel therapeutic targets for osteosarcoma', in Omics, American Association for Cancer Research, presented at Abstracts: Advances in Sarcomas: From Basic Science to Clinical Translation; May 16-19, 2017; Philadelphia, PA, http://dx.doi.org/10.1158/1557-3265.sarcomas17-pr13
    Conference Papers | 2018
    Professor David Thomas
    Cain JE; Cochrane CR; Vaghjiani V; Szczepny A; Mccaw A; Carey K; Martelotto L; Kansara M; Thomas D; Walkley C; Matsui WH; Watkins DN, 2018, 'p53 and RB regulate Hedgehog responsiveness via autophagy-mediated ciliogenesis', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Chicago, IL, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Chicago, IL, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-4994
    Conference Abstracts | 2018
    Professor David Thomas
    Thavaneswaran S; Sebastian L; Ballinger M; Cowley M; Grady J; Joshua A; Lee C; Sjoquist K; Hague W; Simes J; Thomas D, 2018, 'The cancer molecular screening and therapeutics program (MoST): A molecular screening platform with multiple, parallel, signal-seeking therapeutic substudies', in Annals of oncology : official journal of the European Society for Medical Oncology, OXFORD UNIV PRESS, Munich, GERMANY, Vol. 29, pp. viii147, presented at 43rd ESMO Congress (ESMO), Munich, GERMANY, 19 October 2018 - 23 October 2018, http://dx.doi.org/10.1093/annonc/mdy279.434
    Conference Papers | 2017
    Professor David Thomas
    Kansara M; Pang P; Sulkowski N; Teng M; Smyth M; Thomas D, 2017, 'Pivotal role of interleukin 23 in osteosarcoma development and its link with glutamate metabotropic 4: Identification of novel therapeutic targets for osteosarcoma.', in CLINICAL CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Philadelphia, PA, pp. 33 - 34, presented at AACR Special Conference on Advances in Sarcomas - From Basic Science to Clinical Translation, Philadelphia, PA, 16 May 2017 - 19 May 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000422882000036&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Posters | 2017
    Professor David Thomas
    Hess D; Sebastian LT; Sjoquist KM; Lee CK; Hague W; Miller D; Cowley M; Qiu MR; Fox SB; Joshua AM; Simes J; Thomas DM, 2017, 'The Molecular Screening and Therapeutics (MoST) Program: A precision medicine framework for biomarker-driven signal seeking clinical studies for rare cancers.', Chicago, IL, Vol. 35, presented at 53rd Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL, 02 June 2017 - 06 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.TPS2621
    Conference Posters | 2016
    Professor David Thomas
    McBride KA; Schlub TE; Ballinger ML; Thomas DM; Tattersall MHN, 2016, 'International survey of awareness of genetic risk in the clinical sarcoma community', Vol. 12, pp. 133 - 142, http://dx.doi.org/10.1111/ajco.12457
    Conference Abstracts | 2016
    Professor David Thomas
    Jones RM; Melton PE; Rea A; Ingley E; Ballinger ML; Wood DJ; Thomas DM; Moses EK, 2016, 'Whole Exome Sequencing in Multigenerational Mixed Cancer Families Identifies a Putative Risk Variant in the PDIA2 Gene', in GENETIC EPIDEMIOLOGY, WILEY-BLACKWELL, Toronto, CANADA, Vol. 40, pp. 644 - 644, presented at Annual Meeting of the International-Genetic-Epidemiology-Society, Toronto, CANADA, 24 October 2016 - 26 October 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000386034800102&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2015
    Professor David Thomas
    Ashley DM; Gupta S; Truyen T; Wei L; Lorgelly PK; Thomas DM; Fox SB; Venkatesh S, 2015, 'Machine-learning prediction of cancer survival: A prospective study examining the impact of combining clinical and genomic data', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, Chicago, IL, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Clinical Science Symposium on Predicting and Improving Adverse Outcomes in Older Adults with Cancer, Chicago, IL, 29 May 2015 - 02 June 2015, http://dx.doi.org/10.1200/jco.2015.33.15_suppl.6521
    Conference Abstracts | 2015
    Professor David Thomas
    Peng G; Bojadzieva J; Ballinger ML; Thomas DM; Strong L; Wang W, 2015, 'LFSpro: A risk assessment tool to estimate TP53 mutation status in families with Li-Fraumeni syndrome', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Philadelphia, PA, Vol. 75, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia, PA, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-2762
    Conference Abstracts | 2015
    Professor David Thomas
    Thomas D, 2015, 'RANKL and giant cell tumor of bone: the growing problem of benign tumours', in CLINICAL ENDOCRINOLOGY, WILEY, Adelaide, AUSTRALIA, Vol. 84, pp. 3 - 4, presented at Annual Scientific Meeting of the Endocrine-Society-of-Australia, Adelaide, AUSTRALIA, 23 August 2015 - 26 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000372310400010&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Professor David Thomas
    Chantrill L; Nagrial A; Watson C; Johns A; Martyn-Smith M; Simpson S; Mead S; Jones M; Samra J; Gill A; Watson N; Chin V; Humphris J; Chou A; Brown B; Morey A; Thomas D; Sebastian L; Sjoquist K; Yip S; Pavlakis N; Asghari R; Harvey S; Grimison P; Simes J; Biankin A, 2015, 'Precision medicine for advanced pancreas cancer: the individualised molecular pancreatic cancer therapy (IMPACT) trial', in Asia-Pacific Journal of Clinical Oncology, WILEY-BLACKWELL, Vol. 11, pp. 147 - 148, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000364320800239&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Abstracts | 2015
    Professor David Thomas
    McBride KA; Young M-A; Schlub TE; Kirk J; Tattersall MHN; Ballinger M; Thomas D; Mitchell G, 2015, 'THE PSYCHOSOCIAL EFFECTS OF A WHOLE BODY MRI SCREENING TRIAL IN SARCOMA PATIENTS WITH A GERMLINE TP53 MUTATION', in Asia-Pacific Journal of Clinical Oncology, WILEY-BLACKWELL, Vol. 11, pp. 178 - 178, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000364320800325&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Professor David Thomas
    Thomas DM, 2015, 'MANAGING SARCOMA FROM A MEDICAL ONCOLOGIST PERSPECTIVE', in Asia-Pacific Journal of Clinical Oncology, WILEY-BLACKWELL, Vol. 11, pp. 75 - 75, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000364320800041&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Presentations | 2014
    Professor David Thomas
    Thomas D, 2014, 'PULMONARY OLIGOMETASTATIC SARCOMA', Vol. 10, pp. 78 - 78, http://dx.doi.org/10.1111/ajco.12307
    Conference Presentations | 2014
    Professor David Thomas
    Lorgelly P; Doble B; Lucas M; Parisot J; Fox S; Thomas D, 2014, 'WHAT DRIVES THE COST OF CANCER TREATMENT? INSIGHTS FROM AN ANALYSIS OF A LONGITUDINAL COHORT (CANCER 2015) LINKED TO ADMINISTRATIVE REIMBURSEMENT DATA', Vol. 10, pp. 96 - 96, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000345350900067&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Proceedings (Editor of) | 2014
    Professor David Thomas
    2014, 'WHAT DRIVES THE COST OF CANCER TREATMENT? INSIGHTS FROM AN ANALYSIS OF A LONGITUDINAL COHORT (CANCER 2015) LINKED TO ADMINISTRATIVE REIMBURSEMENT DATA', WILEY-BLACKWELL, Vol. 10, pp. 105 - 106, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000346343700315&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Posters | 2014
    Professor David Thomas
    Thomas D; Hicks RJ; Skubitz K; Chawla S; Staddon A; Engellau J; Feng A; Bach BA, 2014, 'RAPID FLUORODEOXYGLUCOSE-POSITRON EMISSION TOMOGRAPHY (FDG-PET) RESPONSE TO DENOSUMAB TREATMENT IN PATIENTS WITH GIANT CELL TUMOUR OF BONE (GCTB): RESULTS FROM TWO PHASE 2 TRIALS', Vol. 10, pp. 190 - 190, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000345350900341&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Posters | 2014
    Professor David Thomas
    McBride KA; Young M-A; Schlub TE; Ballinger ML; Kirk J; Tattersall MH; Thomas DM; Mitchell G, 2014, 'THE PSYCHOLOGICAL IMPACT OF A PILOT WHOLE-BODY SCREENING TRIAL (SMOC) ON INDIVIDUALS WITH LI-FRAUMENI SYNDROME', Vol. 10, pp. 166 - 167, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000345350900277&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2008
    Professor David Thomas
    Davis H; Vetere F; Ashkanasy S; Dyson G; Schofield P; Thompson K; Withers G; Thomas D, 2008, 'Towards social connection for young people with cancer', in Proceedings of the 20th Australasian Conference on Computer-Human Interaction: Designing for Habitus and Habitat, OZCHI'08, pp. 319 - 322, http://dx.doi.org/10.1145/1517744.1517804

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