Professor David Thomas
Conjoint Professor

Professor David Thomas

1988: Bachelor of Medicine and Surgery (University of Melbourne)

1997: Doctorate of Philosophy (University of Melbourne)

1997: Fellowship of the Royal Australasian College of Physicians.

Medicine & Health
School of Clinical Medicine

Dr Thomas is a National Health and Medical Research Council L3 Investigator at the Garvan Institute of Medical Research, as well as CEO of Omico, Australia's Genomic Cancer Medicine Centre. He undertook his basic training in medicine at the University of Melbourne (1982-88), followed by a PhD at the same university (1992-95), and obtained his Fellowship in Medical Oncology from the Royal Australasian College of Physicians in 1997. He then undertook post-doctoral studies at Harvard Medical School (1998-2000), before returning to St Vincents Hospital Department of Medicine in 2001. He then moved his lab to the Peter MacCallum Cancer Centre (2004-14). During this time he established the Australasian Sarcoma Study Group, the International Sarcoma Kindred Study and onTrac@PeterMac. He moved to the Garvan Institute in 2014, taking up Directorship of the Kinghorn Cancer Centre (2014-21) and Head of the Cancer Division of the Garvan Institute (2014-20). He established Omico, a non-profit national oncology platform, in 2018. He was President of the Connective Tissue Oncology Society in 2018.

Phone
02 93555770
  • Book Chapters | 2017
    Neuhaus SJ; Thomas DM, 2017, 'Multidisciplinary approach to treatment: An Australian perspective', in Sarcoma: A Multidisciplinary Approach to Treatment, Springer, pp. 461 - 476, http://dx.doi.org/10.1007/978-3-319-43121-5_23
    Book Chapters | 2017
    Thomas DM; Whelan J, 2017, 'Bone Sarcomas in the Adolescent and Young Adult Population', in Bleyer A; Barr R; Ries L; Whelan J; Ferrari A (ed.), Cancer in Adolescents and Young Adults., edn. 9783319336770, Springer, pp. 417 - 427, http://dx.doi.org/10.1007/978-3-319-33679-4_16
    Book Chapters | 2009
    Orme LM; Palmer S; Thomas D, 2009, 'No-man’s land: Between paediatric and adult medical oncology', in When Cancer Crosses Disciplines: A Physician's Handbook, pp. 885 - 906, http://dx.doi.org/10.1142/9781848163652_0035
  • Journal articles | 2022
    Bartley N; Best MC; Biesecker BB; Fisher A; Goldstein D; Meiser B; Thomas DM; Ballinger ML; Butow P, 2022, 'Effectively communicating comprehensive tumor genomic profiling results: Mitigating uncertainty for advanced cancer patients', Patient Education and Counseling, vol. 105, pp. 452 - 459, http://dx.doi.org/10.1016/j.pec.2021.05.018
    Journal articles | 2022
    Best MC; Bartley N; Napier CE; Fisher A; Ballinger ML; Thomas DM; Goldstein D; Tucker K; Biesecker BB; Butow P, 2022, 'Return of comprehensive tumour genomic profiling results to advanced cancer patients: a qualitative study', Supportive Care in Cancer, vol. 30, pp. 8201 - 8210, http://dx.doi.org/10.1007/s00520-022-07272-3
    Journal articles | 2022
    Best MC; Butow P; Savard J; Jacobs C; Bartley N; Davies G; Napier CE; Ballinger ML; Thomas DM; Biesecker B; Tucker KM; Juraskova I; Meiser B; Schlub T; Newson AJ, 2022, 'Preferences for return of germline genome sequencing results for cancer patients and their genetic relatives in a research setting', European Journal of Human Genetics, vol. 30, pp. 930 - 937, http://dx.doi.org/10.1038/s41431-022-01069-y
    Journal articles | 2022
    Butow P; Davies G; Napier CE; Bartley N; Ballinger ML; Biesecker B; Juraskova I; Meiser B; Schlub T; Thomas DM; Goldstein D; Best MC, 2022, 'Value of whole-genome sequencing to Australian cancer patients and their first-degree relatives participating in a genomic sequencing study', Journal of Genetic Counseling, vol. 31, pp. 96 - 108, http://dx.doi.org/10.1002/jgc4.1455
    Journal articles | 2022
    Butow PN; Best MC; Davies G; Schlub T; Napier CE; Bartley N; Ballinger ML; Juraskova I; Meiser B; Goldstein D; Biesecker B; Thomas DM, 2022, 'Psychological impact of comprehensive tumor genomic profiling results for advanced cancer patients', Patient Education and Counseling, vol. 105, pp. 2206 - 2216, http://dx.doi.org/10.1016/j.pec.2022.01.011
    Journal articles | 2022
    Gounder MM; Agaram NP; Trabucco SE; Robinson V; Ferraro RA; Millis SZ; Krishnan A; Lee J; Attia S; Abida W; Drilon A; Chi P; Angelo SPD; Dickson MA; Keohan ML; Kelly CM; Agulnik M; Chawla SP; Choy E; Chugh R; Meyer CF; Myer PA; Moore JL; Okimoto RA; Pollock RE; Ravi V; Singh AS; Somaiah N; Wagner AJ; Healey JH; Frampton GM; Venstrom JM; Ross JS; Ladanyi M; Singer S; Brennan MF; Schwartz GK; Lazar AJ; Thomas DM; Maki RG; Tap WD; Ali SM; Jin DX, 2022, 'Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma', Nature Communications, vol. 13, pp. 3406, http://dx.doi.org/10.1038/s41467-022-30496-0
    Journal articles | 2022
    Jadhao S; Davison C; Roulis EV; Lee S; Lacaze P; Riaz M; McNeil JJ; Thomas DM; Pecheniuk NM; Hyland CA; Flower RL; Nagaraj SH, 2022, 'Using whole-genome sequencing to characterize clinically significant blood groups among healthy older Australians', Blood Advances, vol. 6, pp. 4593 - 4604, http://dx.doi.org/10.1182/bloodadvances.2022007505
    Journal articles | 2022
    Lacaze PA; Tiller J; Winship I; Winship I; Brotchie A; McNeil J; Zalcberg J; Thomas D; Milne R; James P; Delatycki M; Young MA; Nowak K; Nguyen-Dumont T; Southey M; Ademi Z; Bruinsma F; Riaz M; Terrill B; Kirk J; Tucker K; Andrews L; Pachter N; Susman R; Poplawski N; Wallis M; Watts G; Nicholls S; Macrae F; Sturm A; Green R; Ahern S; Revote J; Von Saldern S; Powell S; Rice T, 2022, 'Population DNA screening for medically actionable disease risk in adults', Medical Journal of Australia, vol. 216, pp. 278 - 280, http://dx.doi.org/10.5694/mja2.51454
    Journal articles | 2022
    Lau LMS; Mayoh C; Xie J; Barahona P; MacKenzie KL; Wong M; Kamili A; Tsoli M; Failes TW; Kumar A; Mould EVA; Gifford A; Chow SO; Pinese M; Fletcher JI; Arndt GM; Khuong-Quang DA; Wadham C; Batey D; Eden G; Trebilcock P; Joshi S; Alfred S; Gopalakrishnan A; Khan A; Grebert Wade D; Strong PA; Manouvrier E; Morgan LT; Span M; Lim JY; Cadiz R; Ung C; Thomas DM; Tucker KM; Warby M; McCowage GB; Dalla-Pozza L; Byrne JA; Saletta F; Fellowes A; Fox SB; Norris MD; Tyrrell V; Trahair TN; Lock RB; Cowley MJ; Ekert PG; Haber M; Ziegler DS; Marshall GM, 2022, 'In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer', EMBO Molecular Medicine, vol. 14, http://dx.doi.org/10.15252/emmm.202114608
    Journal articles | 2022
    Mateo J; Steuten L; Aftimos P; André F; Davies M; Garralda E; Geissler J; Husereau D; Martinez-Lopez I; Normanno N; Reis-Filho JS; Stefani S; Thomas DM; Westphalen CB; Voest E, 2022, 'Delivering precision oncology to patients with cancer', Nature Medicine, vol. 28, pp. 658 - 665, http://dx.doi.org/10.1038/s41591-022-01717-2
    Journal articles | 2022
    Meiser B; Butow P; Davies G; Napier CE; Schlub TE; Bartley N; Juraskova I; Ballinger ML; Thomas DM; Best MC, 2022, 'Psychological predictors of cancer patients' and their relatives’ attitudes towards the return of genomic sequencing results', European Journal of Medical Genetics, vol. 65, pp. 104516, http://dx.doi.org/10.1016/j.ejmg.2022.104516
    Journal articles | 2022
    Meiser B; Butow P; Davies G; Napier CE; Schlub TE; Bartley N; Juraskova I; Ballinger ML; Thomas DM; Tucker K; Goldstein D; Biesecker BB; Best MC, 2022, 'Psychological predictors of advanced cancer patients’ preferences for return of results from comprehensive tumor genomic profiling', American Journal of Medical Genetics, Part A, vol. 188, pp. 725 - 734, http://dx.doi.org/10.1002/ajmg.a.62563
    Journal articles | 2022
    Napier CE; Davies G; Butow PN; Schlub TE; Best MC; Bartley N; Juraskova I; Meiser B; Tucker KM; Biesecker BB; Thomas DM; Ballinger ML, 2022, 'Cancer patient knowledge about and behavioral intentions after germline genome sequencing', Patient Education and Counseling, vol. 105, pp. 707 - 718, http://dx.doi.org/10.1016/j.pec.2021.07.004
    Journal articles | 2022
    Siu DHW; Ali A; Tjokrowidjaja A; De Silva M; Lee J; Clingan PR; Aghmesheh M; Brungs D; Mapagu C; Goldstein D; O'Neill S; Liauw WS; Sjoquist KM; Thomas D; Pavlakis N; Clarke SJ; Diakos C; Chantrill LA, 2022, 'Clinical and molecular profile of young adults with early-onset colorectal cancer: Experience from four Australian tertiary centers', Asia-Pacific Journal of Clinical Oncology, http://dx.doi.org/10.1111/ajco.13745
    Journal articles | 2022
    Stacchiotti S; Maria Frezza A; Demetri GD; Blay JY; Bajpai J; Baldi GG; Baldini EH; Benjamin RS; Bonvalot S; Bovée JVMG; Callegaro D; Casali PG; D'Angelo SP; Davis EJ; Dei Tos AP; Demicco EG; Desai J; Dileo P; Eriksson M; Gelderblom H; George S; Gladdy RA; Gounder MM; Gupta AA; Haas R; Hayes A; Hohenberger P; Jones KB; Jones RL; Kasper B; Kawai A; Kirsch DG; Kleinerman ES; Le Cesne A; Maestro R; Martin Broto J; Maki RG; Miah AB; Palmerini E; Patel SR; Raut CP; Razak ARA; Reed DR; Rutkowski P; Sanfilippo RG; Sbaraglia M; Schaefer IM; Strauss DC; Strauss SJ; Tap WD; Thomas DM; Trama A; Trent JC; van der Graaf WTA; van Houdt WJ; von Mehren M; Wilky BA; Fletcher CDM; Gronchi A; Miceli R; Wagner AJ, 2022, 'Retrospective observational studies in ultra-rare sarcomas: A consensus paper from the Connective Tissue Oncology Society (CTOS) community of experts on the minimum requirements for the evaluation of activity of systemic treatments', Cancer Treatment Reviews, vol. 110, http://dx.doi.org/10.1016/j.ctrv.2022.102455
    Journal articles | 2022
    Sylvester DE; Chen Y; Grima N; Saletta F; Padhye B; Bennetts B; Wright D; Krivanek M; Graf N; Zhou L; Catchpoole D; Kirk J; Latchoumanin O; Qiao L; Ballinger M; Thomas D; Jamieson R; Dalla-Pozza L; Byrne JA, 2022, 'Rare germline variants in childhood cancer patients suspected of genetic predisposition to cancer', Genes Chromosomes and Cancer, vol. 61, pp. 81 - 93, http://dx.doi.org/10.1002/gcc.23006
    Journal articles | 2022
    Tarride JE; Gould T; Thomas DM, 2022, 'Challenges of Conducting Value Assessment for Comprehensive Genomic Profiling', International Journal of Technology Assessment in Health Care, vol. 38, http://dx.doi.org/10.1017/S026646232200040X
    Journal articles | 2022
    Thomas DM; Hackett JM; Plestina S, 2022, 'Unlocking Access to Broad Molecular Profiling: Benefits, Barriers, and Policy Solutions', Public Health Genomics, vol. 25, pp. 70 - 79, http://dx.doi.org/10.1159/000520000
    Journal articles | 2022
    Vatter S; Schlub TE; Napier CE; Best MC; Bartley N; Juraskova I; Meiser B; Ballinger ML; Biesecker BB; Goldstein D; Thomas DM; Butow P, 2022, 'Psychological Outcomes in Advanced Cancer Patients After Receiving Genomic Tumor Profiling Results', Health Psychology, vol. 41, pp. 396 - 408, http://dx.doi.org/10.1037/hea0001181
    Journal articles | 2021
    Alcindor T; Dumitra S; Albritton K; Thomas DM, 2021, 'Disparities in Cancer Care: The Example of Sarcoma-In Search of Solutions for a Global Issue.', Am Soc Clin Oncol Educ Book, vol. 41, pp. 1 - 7, http://dx.doi.org/10.1200/EDBK_320463
    Journal articles | 2021
    Ballinger ML; Thomas D, 2021, 'Heritable cancer risk in the genomic ERA', Pathology, vol. 53, pp. S10 - S10, http://dx.doi.org/10.1016/j.pathol.2021.05.038
    Journal articles | 2021
    Bartley N; Davies G; Butow P; Napier CE; Schlub T; Ballinger ML; Thomas DM; Juraskova I; Meiser B; Best MC, 2021, 'Fear of cancer recurrence in patients undergoing germline genome sequencing', Supportive Care in Cancer, vol. 29, pp. 7289 - 7297, http://dx.doi.org/10.1007/s00520-021-06311-9
    Journal articles | 2021
    Butow P; Müller F; Napier CE; Bartley N; Ballinger ML; Biesecker B; Juraskova I; Meiser B; Schlub TE; Thomas DM; Goldstein D; Best MC; Newson A; Tucker K; Vines R; Vines K; Kirk J; Young MA; Savard J; Jacobs C, 2021, 'Longitudinal patterns in fear of cancer progression in patients with rare, advanced cancers undergoing comprehensive tumour genomic profiling', Psycho-Oncology, vol. 30, pp. 1920 - 1929, http://dx.doi.org/10.1002/pon.5764
    Journal articles | 2021
    Cilento MA; Poplawski NK; Paramasivam S; Thomas DM; Kichenadasse G, 2021, 'Germline PALB2 variants and PARP inhibitors in endometrial cancer', JNCCN Journal of the National Comprehensive Cancer Network, vol. 19, pp. 1212 - 1217, http://dx.doi.org/10.6004/jnccn.2021.7067
    Journal articles | 2021
    Gong B; Li D; Kusko R; Novoradovskaya N; Zhang Y; Wang S; Pabón-Peña C; Zhang Z; Lai K; Cai W; LoCoco JS; Lader E; Richmond TA; Mittal VK; Liu LC; Johann DJ; Willey JC; Bushel PR; Yu Y; Xu C; Chen G; Burgess D; Cawley S; Giorda K; Haseley N; Qiu F; Wilkins K; Arib H; Attwooll C; Babson K; Bao L; Bao W; Lucas AB; Best H; Bhandari A; Bisgin H; Blackburn J; Blomquist TM; Boardman L; Burgher B; Butler DJ; Chang CJ; Chaubey A; Chen T; Chierici M; Chin CR; Close D; Conroy J; Coleman JC; Craig DJ; Crawford E; del Pozo A; Deveson IW; Duncan D; Eterovic AK; Fan X; Foox J; Furlanello C; Ghosal A; Glenn S; Guan M; Haag C; Hang X; Happe S; Hennigan B; Hipp J; Hong H; Horvath K; Hu J; Hung LY; Jarosz M; Kerkhof J; Kipp B; Kreil DP; Łabaj P; Lapunzina P; Li P; Li QZ; Li W; Li Z; Liang Y; Liu S; Liu Z; Ma C; Marella N; Martín-Arenas R; Megherbi DB; Meng Q; Mieczkowski PA; Morrison T; Muzny D; Ning B; Parsons BL; Paweletz CP; Pirooznia M; Qu W; Raymond A; Rindler P; Ringler R; Sadikovic B, 2021, 'Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions', Genome Biology, vol. 22, pp. 109, http://dx.doi.org/10.1186/s13059-021-02315-0
    Journal articles | 2021
    Kaur S; Sikta N; Schafferhans A; Bordin N; Cowley M; Thomas D; Ballinger M; O’Donoghue S, 2021, 'Streamlined use of protein structures in variant analysis', , http://dx.doi.org/10.1101/2021.09.10.459756
    Journal articles | 2021
    Kovac M; Woolley C; Ribi S; Blattmann C; Roth E; Morini M; Kovacova M; Ameline B; Kulozik A; Bielack S; Hartmann W; Ballinger ML; Thomas DM; Tomlinson I; Nathrath M; Heinimann K; Baumhoer D, 2021, 'Germline RET variants underlie a subset of paediatric osteosarcoma', Journal of Medical Genetics, vol. 58, pp. 20 - 24, http://dx.doi.org/10.1136/jmedgenet-2019-106734
    Journal articles | 2021
    Lin FP; Thavaneswaran S; Grady JP; Ballinger M; Kansara M; Oakes SR; Desai J; Lee CK; Simes J; Thomas DM, 2021, 'Criteria-based curation of a therapy-focused compendium to support treatment recommendations in precision oncology', npj Precision Oncology, vol. 5, http://dx.doi.org/10.1038/s41698-021-00194-z
    Journal articles | 2021
    Minoche AE; Lundie B; Peters GB; Ohnesorg T; Pinese M; Thomas DM; Zankl A; Roscioli T; Schonrock N; Kummerfeld S; Burnett L; Dinger ME; Cowley MJ, 2021, 'ClinSV: clinical grade structural and copy number variant detection from whole genome sequencing data', Genome Medicine, vol. 13, http://dx.doi.org/10.1186/s13073-021-00841-x
    Journal articles | 2021
    Mweempwa A; Xu H; Vissers JHA; Tothill RW; Pattison AD; Fellowes AP; Thomas DM; Richardson G; Hicks RJ; Grimmond SM; Fox SB; Luen SJ; Desai J; Solomon BJ, 2021, 'Novel RET fusion RET-SEPTIN9 predicts response to selective RET inhibition with selpercatinib in malignant pheochromocytoma', JCO Precision Oncology, vol. 5, pp. 1160 - 1165, http://dx.doi.org/10.1200/PO.21.00127
    Journal articles | 2021
    Sabesan S; Malica M; Gebbie C; Scott C; Thomas D; Zalcberg J, 2021, 'Implementation of the Australasian Teletrial Model: Translating idea into action using implementation science frameworks', Journal of Telemedicine and Telecare, pp. 1357633X211017805, http://dx.doi.org/10.1177/1357633X211017805
    Journal articles | 2021
    Scheinberg T; Lomax A; Tattersall M; Thomas D; McCowage G; Sullivan M; Karim R; Luk PP; Mahar A; Bonar F; Bhadri VA, 2021, 'PD-1 blockade using pembrolizumab in adolescent and young adult patients with advanced bone and soft tissue sarcoma', Cancer Reports, vol. 4, http://dx.doi.org/10.1002/cnr2.1327
    Journal articles | 2021
    Singhal D; Hahn CN; Feurstein S; Wee LYA; Moma L; Kutyna MM; Chhetri R; Eshraghi L; Schreiber AW; Feng J; Wang PPS; Babic M; Parker WT; Gao S; Moore S; Das S; Thomas D; Pattnaik S; Brown AL; D’Andrea RJ; Poplawski NK; Thomas D; Scott HS; Godley LA; Hiwase DK, 2021, 'Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancer', Leukemia, vol. 35, pp. 3245 - 3256, http://dx.doi.org/10.1038/s41375-021-01246-w
    Journal articles | 2021
    Smit AK; Bartley N; Best MC; Napier CE; Butow P; Newson AJ; Tucker K; Ballinger ML; Thomas DM; Jacobs C; Meiser B; Goldstein D; Savard J; Juraskova I, 2021, 'Family communication about genomic sequencing: A qualitative study with cancer patients and relatives', Patient Education and Counseling, vol. 104, pp. 944 - 952, http://dx.doi.org/10.1016/j.pec.2020.10.022
    Journal articles | 2021
    Stacchiotti S; Frezza AM; Blay JY; Baldini EH; Bonvalot S; Bovée JVMG; Callegaro D; Casali PG; Chiang RRCJ; Demetri GD; Demicco EG; Desai J; Eriksson M; Gelderblom H; George S; Gounder MM; Gronchi A; Gupta A; Haas RL; Hayes-Jardon A; Hohenberger P; Jones KB; Jones RL; Kasper B; Kawai A; Kirsch DG; Kleinerman ES; Le Cesne A; Lim J; Chirlaque López MD; Maestro R; Marcos-Gragera R; Martin Broto J; Matsuda T; Mir O; Patel SR; Raut CP; Razak ARA; Reed DR; Rutkowski P; Sanfilippo RG; Sbaraglia M; Schaefer IM; Strauss DC; Sundby Hall K; Tap WD; Thomas DM; van der Graaf WTA; van Houdt WJ; Visser O; von Mehren M; Wagner AJ; Wilky BA; Won YJ; Fletcher CDM; Dei Tos AP; Trama A, 2021, 'Ultra-rare sarcomas: A consensus paper from the Connective Tissue Oncology Society community of experts on the incidence threshold and the list of entities', Cancer, vol. 127, pp. 2934 - 2942, http://dx.doi.org/10.1002/cncr.33618
    Journal articles | 2021
    Thavaneswaran S; Ballinger M; Butow P; Meiser B; Goldstein D; Lin F; Napier C; Thomas D; Best M, 2021, 'The experiences and needs of australian medical oncologists in integrating comprehensive genomic profiling into clinical care: A nation-wide survey', Oncotarget, vol. 12, pp. 2169 - 2176, http://dx.doi.org/10.18632/ONCOTARGET.28076
    Journal articles | 2021
    Vatter S; Bartley N; Best M; Juraskova I; Jacobs C; Ballinger ML; Thomas DM; Butow P, 2021, 'Does undertaking genome sequencing prompt actual and planned lifestyle-related behavior change in cancer patients and survivors? A qualitative study', Journal of Psychosocial Oncology Research & Practice, vol. 3, pp. e059 - e059, http://dx.doi.org/10.1097/or9.0000000000000059
    Journal articles | 2021
    Willis AM; Smith SK; Meiser B; James PA; Ballinger ML; Thomas DM; Yanes T; Young MA, 2021, 'Influence of lived experience on risk perception among women who received a breast cancer polygenic risk score: ‘Another piece of the pie’', Journal of Genetic Counseling, vol. 30, pp. 849 - 860, http://dx.doi.org/10.1002/jgc4.1384
    Journal articles | 2020
    Ballinger ML; Thomas D, 2020, 'Heritable cancer risk in the genomic era', Pathology, vol. 52, pp. S28 - S29, http://dx.doi.org/10.1016/j.pathol.2020.01.118
    Journal articles | 2020
    Bartley N; Best M; Jacobs C; Juraskova I; Newson AJ; Savard J; Meiser B; Ballinger ML; Thomas DM; Biesecker B; Butow P, 2020, 'Cancer patients' views and understanding of genome sequencing: A qualitative study', Journal of Medical Genetics, vol. 57, pp. 671 - 676, http://dx.doi.org/10.1136/jmedgenet-2019-106410
    Journal articles | 2020
    Best MC; Butow P; Jacobs C; Savard J; Biesecker B; Ballinger ML; Bartley N; Davies G; Napier CE; Smit AK; Thomas DM; Newson AJ, 2020, 'Who should access germline genome sequencing? A mixed methods study of patient views', Clinical Genetics, vol. 97, pp. 329 - 337, http://dx.doi.org/10.1111/cge.13664
    Journal articles | 2020
    Butow P; Butow P; Davies G; Napier CE; Schlub T; Best MC; Bartley N; Juraskova I; Meiser B; Ballinger ML; Biesecker B; Goldstein D; Thomas DM, 2020, 'Assessment of the Value of Tumor Variation Profiling Perceived by Patients with Cancer', JAMA Network Open, vol. 3, pp. e204721, http://dx.doi.org/10.1001/jamanetworkopen.2020.4721
    Journal articles | 2020
    Butow P; Davies G; Napier C; Thomas DM; Bartley N; Goldstein D; Ballinger ML; Juraskova I; Schlub TE; Tucker K; Meiser B; Young M-A, 2020, 'Return of results after somatic tumor mutation profiling in advanced cancer: Psychological impacts.', Journal of Clinical Oncology, vol. 38, pp. 1541 - 1541, http://dx.doi.org/10.1200/jco.2020.38.15_suppl.1541
    Journal articles | 2020
    Cipponi A; Goode DL; Bedo J; McCabe MJ; Pajic M; Croucher DR; Rajal AG; Junankar SR; Saunders DN; Lobachevsky P; Papenfuss AT; Nessem D; Nobis M; Warren SC; Timpson P; Cowley M; Vargas AC; Qiu MR; Generali DG; Keerthikumar S; Nguyen U; Corcoran NM; Long GV; Blay J-Y; Thomas DM; McCabe M, 2020, 'MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer', Science
    Journal articles | 2020
    Dancsok AR; Gao D; Lee AF; Steigen SE; Blay JY; Thomas DM; Maki RG; Nielsen TO; Demicco EG, 2020, 'Tumor-associated macrophages and macrophage-related immune checkpoint expression in sarcomas', OncoImmunology, vol. 9, http://dx.doi.org/10.1080/2162402X.2020.1747340
    Journal articles | 2020
    Davies G; Butow P; Napier CE; Bartley N; Juraskova I; Meiser B; Ballinger ML; Thomas DM; Schlub TE; Best MC, 2020, 'Advanced Cancer Patient Knowledge of and Attitudes towards Tumor Molecular Profiling', Translational Oncology, vol. 13, pp. 100799, http://dx.doi.org/10.1016/j.tranon.2020.100799
    Journal articles | 2020
    Demetri GD; Antonescu CR; Bjerkehagen B; Bovée JVMG; Boye K; Chacón M; Dei Tos AP; Desai J; Fletcher JA; Gelderblom H; George S; Gronchi A; Haas RL; Hindi N; Hohenberger P; Joensuu H; Jones RL; Judson I; Kang YK; Kawai A; Lazar AJ; Le Cesne A; Maestro R; Maki RG; Martín J; Patel S; Penault-Llorca F; Premanand Raut C; Rutkowski P; Safwat A; Sbaraglia M; Schaefer IM; Shen L; Serrano C; Schöffski P; Stacchiotti S; Sundby Hall K; Tap WD; Thomas DM; Trent J; Valverde C; van der Graaf WTA; von Mehren M; Wagner A; Wardelmann E; Naito Y; Zalcberg J; Blay JY, 2020, 'Diagnosis and management of tropomyosin receptor kinase (TRK) fusion sarcomas: expert recommendations from the World Sarcoma Network', Annals of Oncology, vol. 31, pp. 1506 - 1517, http://dx.doi.org/10.1016/j.annonc.2020.08.2232
    Journal articles | 2020
    Heyer EE; Deveson IW; Wooi D; Selinger CI; Lyons RJ; Hayes VM; O’Toole SA; Ballinger ML; Gill D; Thomas DM; Mercer TR; Blackburn J, 2020, 'Author Correction: Diagnosis of fusion genes using targeted RNA sequencing (Nature Communications, (2019), 10, 1, (1388), 10.1038/s41467-019-09374-9)', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-020-15697-9
    Journal articles | 2020
    Joshua AM; Prawira A; Thavaneswaran S; Cosman R; Lee CK; Sjoquist KM; Simes J; Thomas DM; Espinoza D; Sebastian L; Ballinger ML; Hague W; Chinchen S; Collignon E; Kansara M; Palacios T; Grady J; Barker H; Thornton K, 2020, 'A signal-seeking trial of olaparib and durvalumab in homologous repair-deficient tumors: A sub-study of the cancer molecular screening and therapeutics (MoST) program.', Journal of Clinical Oncology, vol. 38, pp. 3073 - 3073, http://dx.doi.org/10.1200/jco.2020.38.15_suppl.3073
    Journal articles | 2020
    Kalachand RD; Stordal B; Madden S; Chandler B; Cunningham J; Goode EL; Ruscito I; Braicu EI; Sehouli J; Ignatov A; Yu H; Katsaros D; Mills GB; Lu KH; Carey MS; Timms KM; Kupryjanczyk J; Rzepecka IK; Podgorska A; McAlpine JN; Swisher EM; Bernards SS; O'Riain C; O'Toole S; O'Leary JJ; Bowtell DD; Thomas DM; Prieske K; Joosse SA; Woelber L; Chaudhry P; Häfner N; Runnebaum IB; Hennessy BT, 2020, 'BRCA1 Promoter Methylation and Clinical Outcomes in Ovarian Cancer: An Individual Patient Data Meta-Analysis', Journal of the National Cancer Institute, vol. 112, pp. 1190 - 1203, http://dx.doi.org/10.1093/jnci/djaa070
    Journal articles | 2020
    Lim LE; Chan DL; Thomas D; Du Y; Tincknell G; Kuchel A; Davis A; Bailey DL; Pavlakis N; Cehic G; Macdonald W; Wyld D; Segelov E, 2020, 'Australian experience of peptide receptor radionuclide therapy in lung neuroendocrine tumours', Oncotarget, vol. 11, pp. 2636 - 2646, http://dx.doi.org/10.18632/oncotarget.27659
    Journal articles | 2020
    Lin F; Thavaneswaran S; Grady J; Ballinger M; Kansara M; Oakes S; Desai J; Lee CK; Simes J; Thomas D, 2020, 'Criteria-based curation of a therapy-focused compendium to support treatment recommendations in precision oncology', , http://dx.doi.org/10.1101/2020.12.18.20248521
    Journal articles | 2020
    Mirabello L; Zhu B; Koster R; Karlins E; Dean M; Yeager M; Gianferante M; Spector LG; Morton LM; Karyadi D; Robison LL; Armstrong GT; Bhatia S; Song L; Pankratz N; Pinheiro M; Gastier-Foster JM; Gorlick R; De Toledo SRC; Petrilli AS; Patino-Garcia A; Lecanda F; Gutierrez-Jimeno M; Serra M; Hattinger C; Picci P; Scotlandi K; Flanagan AM; Tirabosco R; Amary MF; Kurucu N; Ilhan IE; Ballinger ML; Thomas DM; Barkauskas DA; Mejia-Baltodano G; Valverde P; Hicks BD; Wang M; Hutchinson AA; Tucker M; Sampson J; Landi MT; Freedman ND; Gapstur S; Carter B; Hoover RN; Chanock SJ; Savage SA, 2020, 'Frequency of Pathogenic Germline Variants in Cancer-Susceptibility Genes in Patients with Osteosarcoma', JAMA Oncology, vol. 6, pp. 724 - 734, http://dx.doi.org/10.1001/jamaoncol.2020.0197
    Journal articles | 2020
    Pinese M; Lacaze P; Rath EM; Stone A; Brion MJ; Ameur A; Nagpal S; Puttick C; Husson S; Degrave D; Cristina TN; Kahl VFS; Statham AL; Woods RL; McNeil JJ; Riaz M; Barr M; Nelson MR; Reid CM; Murray AM; Shah RC; Wolfe R; Atkins JR; Fitzsimmons C; Cairns HM; Green MJ; Carr VJ; Cowley MJ; Pickett HA; James PA; Powell JE; Kaplan W; Gibson G; Gyllensten U; Cairns MJ; McNamara M; Dinger ME; Thomas DM, 2020, 'The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-019-14079-0
    Journal articles | 2020
    Shin SJ; Dodd-Eaton EB; Peng G; Bojadzieva J; Chen J; Amos CI; Frone MN; Khincha PP; Mai PL; Savage SA; Ballinger ML; Thomas DM; Yuan Y; Strong LC; Wang W, 2020, 'Penetrance of different cancer types in families with Li-Fraumeni syndrome: A validation study using multicenter cohorts', Cancer Research, vol. 80, pp. 354 - 360, http://dx.doi.org/10.1158/0008-5472.CAN-19-0728
    Journal articles | 2020
    Wong M; Mayoh C; Lau LMS; Khuong-Quang DA; Pinese M; Kumar A; Barahona P; Wilkie EE; Sullivan P; Bowen-James R; Syed M; Martincorena I; Abascal F; Sherstyuk A; Bolanos NA; Baber J; Priestley P; Dolman MEM; Fleuren EDG; Gauthier ME; Mould EVA; Gayevskiy V; Gifford AJ; Grebert-Wade D; Strong PA; Manouvrier E; Warby M; Thomas DM; Kirk J; Tucker K; O’Brien T; Alvaro F; McCowage GB; Dalla-Pozza L; Gottardo NG; Tapp H; Wood P; Khaw SL; Hansford JR; Moore AS; Norris MD; Trahair TN; Lock RB; Tyrrell V; Haber M; Marshall GM; Ziegler DS; Ekert PG; Cowley MJ, 2020, 'Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer', Nature Medicine, vol. 26, pp. 1742 - 1753, http://dx.doi.org/10.1038/s41591-020-1072-4
    Journal articles | 2020
    Zaheed M; Tucker K; Ballinger ML; Thomas DM, 2020, 'Genotype and phenotype correlation of common cancer predisposition syndromes in sarcoma cases.', Journal of Clinical Oncology, vol. 38, pp. 1524 - 1524, http://dx.doi.org/10.1200/jco.2020.38.15_suppl.1524
    Journal articles | 2019
    Best MC; Bartley N; Jacobs C; Juraskova I; Goldstein D; Newson AJ; Savard J; Meiser B; Ballinger M; Napier C; Thomas D; Biesecker B; Butow P; Tucker K; Schlub T; Vines R; Vines K; Kirk J; Young MA, 2019, 'Patient perspectives on molecular tumor profiling: "why wouldn't you?"', BMC Cancer, vol. 19, pp. 753, http://dx.doi.org/10.1186/s12885-019-5920-x
    Journal articles | 2019
    Dancsok AR; Setsu N; Gao D; Blay JY; Thomas D; Maki RG; Nielsen TO; Demicco EG, 2019, 'Expression of lymphocyte immunoregulatory biomarkers in bone and soft-tissue sarcomas', Modern Pathology, vol. 32, pp. 1772 - 1785, http://dx.doi.org/10.1038/s41379-019-0312-y
    Journal articles | 2019
    Fortuno C; Cipponi A; Ballinger ML; Tavtigian SV; Olivier M; Ruparel V; Haupt Y; Haupt S; Study ISK; Tucker K; Spurdle AB; Thomas DM; James PA, 2019, 'A quantitative model to predict pathogenicity of missense variants in the TP53 gene', Human Mutation, vol. 40, pp. 788 - 800, http://dx.doi.org/10.1002/humu.23739
    Journal articles | 2019
    Heyer EE; Deveson IW; Wooi D; Selinger CI; Lyons RJ; Hayes VM; O’Toole SA; Ballinger ML; Gill D; Thomas DM; Mercer TR; Blackburn J, 2019, 'Diagnosis of fusion genes using targeted RNA sequencing', Nature Communications, vol. 10, http://dx.doi.org/10.1038/s41467-019-09374-9
    Journal articles | 2019
    Jones RM; Melton PE; Pinese M; Rea AJ; Ingley E; Ballinger ML; Wood DJ; Thomas DM; Moses EK, 2019, 'Identification of novel sarcoma risk genes using a two-stage genome wide DNA sequencing strategy in cancer cluster families and population case and control cohorts', BMC Medical Genetics, vol. 20, http://dx.doi.org/10.1186/s12881-019-0808-9
    Journal articles | 2019
    Kansara M; Thomson K; Pang P; Dutour A; Mirabello L; Acher F; Pin JP; Demicco EG; Yan J; Teng MWL; Smyth MJ; Thomas DM, 2019, 'Infiltrating myeloid cells drive osteosarcoma progression via GRM4 regulation of IL23', Cancer Discovery, vol. 9, pp. 1511 - 1519, http://dx.doi.org/10.1158/2159-8290.CD-19-0154
    Journal articles | 2019
    Lacaze P; Pinese M; Kaplan W; Stone A; Brion MJ; Woods RL; McNamara M; McNeil JJ; Dinger ME; Thomas DM, 2019, 'The Medical Genome Reference Bank: a whole-genome data resource of 4000 healthy elderly individuals. Rationale and cohort design', European Journal of Human Genetics, vol. 27, pp. 308 - 316, http://dx.doi.org/10.1038/s41431-018-0279-z
    Journal articles | 2019
    Lim LE; Chan DL; Thomas D; Wyld DK; Cehic G; Macdonald W; Du YT; Tincknell G; Kuchel A; Pavlakis N; Bailey D; Davis A; Segelov E, 2019, 'An Australian multi-centre experience of the use of peptide receptor radionuclide therapy for bronchial carcinoid tumours', Annals of Oncology, vol. 30, pp. v572 - v572, http://dx.doi.org/10.1093/annonc/mdz256.021
    Journal articles | 2019
    McCabe MJ; Pinese M; Chan CL; Sheriff N; Thompson TJ; Grady J; Wong M; Gauthier MEA; Puttick C; Gayevskiy V; Hajdu E; Wong SQ; Barrett W; Earls P; Lukeis R; Cheng YY; Lin RCY; Thomas DM; Watkins DN; Dinger ME; McCormack AI; Cowley MJ, 2019, 'Genomic stratification and liquid biopsy in a rare adrenocortical carcinoma (ACC) case, with dual lung metastases', Cold Spring Harbor Molecular Case Studies, vol. 5, http://dx.doi.org/10.1101/mcs.a003764
    Journal articles | 2019
    Puttick C; Kumar K; Davis R; Pinese M; Thomas D; Dinger M; Sue C; Cowley M, 2019, 'mity: A highly sensitive mitochondrial variant analysis pipeline for whole genome sequencing data', , http://dx.doi.org/10.1101/852210
    Journal articles | 2019
    Tap WD; Gelderblom H; Palmerini E; Desai J; Bauer S; Blay JY; Alcindor T; Ganjoo K; Martín-Broto J; Ryan CW; Thomas DM; Peterfy C; Healey JH; van de Sande M; Gelhorn HL; Shuster DE; Wang Q; Yver A; Hsu HH; Lin PS; Tong-Starksen S; Stacchiotti S; Wagner AJ, 2019, 'Pexidartinib versus placebo for advanced tenosynovial giant cell tumour (ENLIVEN): a randomised phase 3 trial', The Lancet, vol. 394, pp. 478 - 487, http://dx.doi.org/10.1016/S0140-6736(19)30764-0
    Journal articles | 2019
    Thavaneswaran S; Napier C; Goldstein D; Meiser B; Butow P; Thomas DM; Ballinger ML; Best M, 2019, 'Medical oncologists’ experience with returning molecular tumor profiling to patients.', Journal of Clinical Oncology, vol. 37, pp. 10521 - 10521, http://dx.doi.org/10.1200/jco.2019.37.15_suppl.10521
    Journal articles | 2019
    Thavaneswaran S; Rath E; Tucker K; Joshua AM; Hess D; Pinese M; Ballinger ML; Thomas DM, 2019, 'Author Correction: Therapeutic implications of germline genetic findings in cancer (Nature Reviews Clinical Oncology, (2019), 16, 6, (386-396), 10.1038/s41571-019-0179-3)', Nature Reviews Clinical Oncology, vol. 16, pp. 397, http://dx.doi.org/10.1038/s41571-019-0212-6
    Journal articles | 2019
    Thavaneswaran S; Rath E; Tucker K; Joshua AM; Hess D; Pinese M; Ballinger ML; Thomas DM, 2019, 'Therapeutic implications of germline genetic findings in cancer', Nature Reviews Clinical Oncology, vol. 16, pp. 386 - 396, http://dx.doi.org/10.1038/s41571-019-0179-3
    Journal articles | 2019
    Vargas AC; Selinger C; Satgunaseelan L; Cooper WA; Gupta R; Stalley P; Brown W; Soper J; Schatz J; Boyle R; Thomas DM; Tattersall MHN; Bhadri V; Maclean F; Bonar SF; Scolyer RA; Karim RZ; McCarthy SW; Mahar A; O'Toole SA, 2019, 'FISH analysis of selected soft tissue tumors: Diagnostic experience in a tertiary center', Asia-Pacific Journal of Clinical Oncology, vol. 15, pp. 38 - 47, http://dx.doi.org/10.1111/ajco.12980
    Journal articles | 2018
    Best M; Newson AJ; Meiser B; Juraskova I; Goldstein D; Tucker K; Ballinger ML; Hess D; Schlub TE; Biesecker B; Vines R; Vines K; Thomas D; Young MA; Savard J; Jacobs C; Butow P, 2018, 'The PiGeOn project: Protocol of a longitudinal study examining psychosocial and ethical issues and outcomes in germline genomic sequencing for cancer', BMC Cancer, vol. 18, http://dx.doi.org/10.1186/s12885-018-4366-x
    Journal articles | 2018
    Chan EKF; Cameron DL; Petersen DC; Lyons RJ; Baldi BF; Papenfuss AT; Thomas DM; Hayes VM, 2018, 'Optical mapping reveals a higher level of genomic architecture of chained fusions in cancer', Genome Research, vol. 28, pp. 726 - 738, http://dx.doi.org/10.1101/gr.227975.117
    Journal articles | 2018
    Gounder MM; Thomas DM; Tap WD, 2018, 'Locally aggressive connective tissue tumors', Journal of Clinical Oncology, vol. 36, pp. 202 - 209, http://dx.doi.org/10.1200/JCO.2017.75.8482
    Journal articles | 2018
    Jones RL; Blay J-Y; Agulnik M; Chugh R; Mir O; Italiano A; Thomas D; Gupta A; Jahan T; Cote G; Villalobos V; Demetri GDD; Roche M; Sapir I; Daigle S; Clawson A; Gounder M, 2018, 'A phase II, multicenter study of the EZH2 inhibitor tazemetostat in adults (rhabdoid tumor cohort) (NCT02601950)', Annals of Oncology, vol. 29, pp. viii580 - viii581, http://dx.doi.org/10.1093/annonc/mdy299.011
    Journal articles | 2018
    Koster R; Panagiotou OA; Wheeler WA; Karlins E; Gastier-Foster JM; Caminada de Toledo SR; Petrilli AS; Flanagan AM; Tirabosco R; Andrulis IL; Wunder JS; Gokgoz N; Patiño-Garcia A; Lecanda F; Serra M; Hattinger C; Picci P; Scotlandi K; Thomas DM; Ballinger ML; Gorlick R; Barkauskas DA; Spector LG; Tucker M; Belynda DH; Yeager M; Hoover RN; Wacholder S; Chanock SJ; Savage SA; Mirabello L, 2018, 'Genome-wide association study identifies the GLDC/IL33 locus associated with survival of osteosarcoma patients', International Journal of Cancer, vol. 142, pp. 1594 - 1601, http://dx.doi.org/10.1002/ijc.31195
    Journal articles | 2018
    Liu Z; Martin J; Orme L; Seddon B; Desai J; Nicholls W; Thomson D; Porter D; McCowage G; Underhill C; Cranswick N; Michael M; Zacharin M; Herschtal A; Sivasuthan J; Thomas DM, 2018, 'Gender differences in doxorubicin pharmacology for subjects with chemosensitive cancers of young adulthood', Cancer Chemotherapy and Pharmacology, vol. 82, pp. 887 - 898, http://dx.doi.org/10.1007/s00280-018-3683-8
    Journal articles | 2018
    Pattnaik S; Vacher C; Lee HC; Kaplan W; Thomas D; Wu J; Pinese M, 2018, 'Network-aware mutation clustering of cancer', BIORXIV, http://dx.doi.org/10.1101/432872
    Journal articles | 2018
    Rasmussen V; Forrest LE; Rogasik M; Girodet M; Meeus P; Sunyach MP; Blay JY; Bally O; Brahmi M; Ballinger ML; Niedermayr E; Thomas DM; Halliday J; James P; Ray-Coquard I; Young MA, 2018, 'A comparison of Australian and French families affected by sarcoma: Perceptions of genetics and incidental findings', Personalized Medicine, vol. 15, pp. 13 - 24, http://dx.doi.org/10.2217/pme-2017-0035
    Journal articles | 2018
    Stacchiotti S; Blay J-Y; Jones RL; Demetri GDD; Mir O; Italiano A; Thomas D; Chen TW-W; Schöffski P; Gil T; Jahan T; Cote G; Ratan R; Attia S; Roche M; Daigle S; Sapir I; Clawson A; Gounder M, 2018, 'A phase II, multicenter study of the EZH2 inhibitor tazemetostat in adults (INI1-negative tumors cohort) (NCT02601950)', Annals of Oncology, vol. 29, pp. viii580 - viii580, http://dx.doi.org/10.1093/annonc/mdy299.010
    Journal articles | 2018
    Thavaneswaran S; Sebastian L; Ballinger M; Best M; Hess D; Lee CK; Sjoquist KM; Hague WE; Butow PN; Simes RJ; Thomas D, 2018, 'Cancer Molecular Screening and Therapeutics (MoST): A framework for multiple, parallel signal-seeking studies of targeted therapies for rare and neglected cancers', Medical Journal of Australia, vol. 209, pp. 354.e1 - 354.e6, http://dx.doi.org/10.5694/MJA18.00227
    Journal articles | 2018
    Thomas D; Hare B; Cameron I, 2018, 'Using body mapping as part of the risk assessment process - a case study', POLICY AND PRACTICE IN HEALTH AND SAFETY, vol. 16, pp. 224 - 240, http://dx.doi.org/10.1080/14773996.2018.1491146
    Journal articles | 2018
    Walczak A; Patterson P; Thomas D, 2018, 'Trials and tribulations: improving outcomes for adolescents and young adults with rare and low survival cancers', The Medical journal of Australia, vol. 209, pp. 330 - 332, http://dx.doi.org/10.5694/mja17.00976
    Journal articles | 2018
    Willis AM; Smith SK; Meiser B; Ballinger ML; Thomas DM; Tattersall M; Young MA, 2018, 'Development and Pilot Testing of a Decision Aid for Genomic Research Participants Notified of Clinically Actionable Research Findings for Cancer Risk', Journal of Genetic Counseling, vol. 27, pp. 1055 - 1066, http://dx.doi.org/10.1007/s10897-018-0223-y
    Journal articles | 2018
    Woodcock F; Doble B; Fox SB; Collins I; Hayes T; Singh M; Richardson G; Lipton L; Moon SY; Lucas M; Fellowes A; Xu H; Thorne H; McNeil JJ; Lorgelly P; Thomas DM; James PA; John T; Risbridger G; Wright G; Snyder R, 2018, 'Mapping the EORTC-QLQ-C30 to the EQ-5D-3L: An Assessment of Existing and Newly Developed Algorithms', Medical Decision Making, vol. 38, pp. 954 - 967, http://dx.doi.org/10.1177/0272989X18797588
    Journal articles | 2017
    Ballinger ML; Best A; Mai PL; Khincha PP; Loud JT; Peters JA; Achatz MI; Chojniak R; Balieiro Da Costa A; Santiago KM; Garber J; O'Neill AF; Eeles RA; Evans DG; Bleiker E; Sonke GS; Ruijs M; Loo C; Schiffman J; Naumer A; Kohlmann W; Strong LC; Bojadzieva J; Malkin D; Rednam SP; Stoffel EM; Koeppe E; Weitzel JN; Slavin TP; Nehoray B; Robson M; Walsh M; Manelli L; Villani A; Thomas DM; Savage SA, 2017, 'Baseline surveillance in li-fraumeni syndrome using whole-body magnetic resonance imaging ameta-analysis', JAMA Oncology, vol. 3, pp. 1634 - 1639, http://dx.doi.org/10.1001/jamaoncol.2017.1968
    Journal articles | 2017
    Ballinger ML; Ferris NJ; Moodie K; Mitchell G; Shanley S; James PA; Thomas DM, 2017, 'Surveillance in Germline TP53 Mutation Carriers Utilizing Whole-Body Magnetic Resonance Imaging', JAMA oncology, vol. 3, pp. 1735 - 1736, http://dx.doi.org/10.1001/jamaoncol.2017.1355
    Journal articles | 2017
    Doble B; John T; Thomas D; Fellowes A; Fox S; Lorgelly P, 2017, 'Cost-effectiveness of precision medicine in the fourth-line treatment of metastatic lung adenocarcinoma: An early decision analytic model of multiplex targeted sequencing', Lung Cancer, vol. 107, pp. 22 - 35, http://dx.doi.org/10.1016/j.lungcan.2016.05.024
    Journal articles | 2017
    Fleuren EDG; Vlenterie M; Van Der Graaf WTA; Hillebrandt-Roeffen MHS; Blackburn J; Ma X; Chan H; Magias MC; Van Erp A; Van Houdt L; Cebeci SAS; Van De Ven A; Flucke UE; Heyer EE; Thomas DM; Lord CJ; Marini KD; Vaghjiani V; Mercer TR; Cain JE; Wu J; Versleijen-Jonkers YMH; Daly RJ, 2017, 'Phosphoproteomic profiling reveals ALK and MET as novel actionable targets across synovial sarcoma subtypes', Cancer Research, vol. 77, pp. 4279 - 4292, http://dx.doi.org/10.1158/0008-5472.CAN-16-2550
    Journal articles | 2017
    Leung DH; Heltshe SL; Borowitz D; Gelfond D; Kloster M; Heubi JE; Stalvey M; Ramsey BW; Stecenko A; Schechter M; Hunter E; Hoover W; Hathorne H; Brand K; Filbrun A; Linn M; Borowitz D; Caci N; McWilliams B; Brazil I; Bushman M; McColley S; Bowen A; McCoy K; Sakellaris K; Sharma P; Cannon C; Hebert A; Sagel S; Anthony M; Dyson M; Urbanek H; Millard S; Gile C; Graff G; Allwein L; Hiatt P; Schaap N; Krupp N; Bendy L; Ahrens R; Teresi M; Berlinski A; Ramsey LL; McNamara J; Johnson M; Brown R; Berry P; Mehdi N; Royall J; Thomas D; Rubenstein R; Donnelly E; Weiner D; Hurban S; Hartigan E; Powers M; Simmons K; Chatfield B; Oldroyd H; Hoffman L; McNamara S; Wooldridge J; Cooper A; Faro A; Rodgers D; Fortner C; Suttmore V; Hocevar-Trnka J; Skalland M; Fowler A, 2017, 'Effects of diagnosis by newborn screening for cystic fibrosis on weight and length in the first year of life', JAMA Pediatrics, vol. 171, pp. 546 - 554, http://dx.doi.org/10.1001/jamapediatrics.2017.0206
    Journal articles | 2017
    Lorgelly PK; Doble B; Rowen D; Brazier J; Thomas DM; Fox SB; Thorne H; Parisot JP; Doig K; Fellowes A; Dobrovic A; James PA; Lipton L; Ashley D; Hayes T; McMurrick P; Richardson G; Lucas M; McNeil JJ; John T, 2017, 'Condition-specific or generic preference-based measures in oncology? A comparison of the EORTC-8D and the EQ-5D-3L', Quality of Life Research, vol. 26, pp. 1163 - 1176, http://dx.doi.org/10.1007/s11136-016-1443-y
    Journal articles | 2017
    McBride KA; Ballinger ML; Schlub TE; Young MA; Tattersall MHN; Kirk J; Eeles R; Killick E; Walker LG; Shanley S; Thomas DM; Mitchell G, 2017, 'Psychosocial morbidity in TP53 mutation carriers: is whole-body cancer screening beneficial?', Familial Cancer, vol. 16, pp. 423 - 432, http://dx.doi.org/10.1007/s10689-016-9964-7
    Journal articles | 2017
    Peng G; Bojadzieva J; Ballinger ML; Li J; Blackford AL; Mai PL; Savage SA; Thomas DM; Strong LC; Wang W, 2017, 'Estimating TP53 mutation carrier probability in families with li-fraumeni syndrome using LFSPRO', Cancer Epidemiology Biomarkers and Prevention, vol. 26, pp. 837 - 844, http://dx.doi.org/10.1158/1055-9965.EPI-16-0695
    Journal articles | 2017
    Takeda K; Nakayama M; Hayakawa Y; Kojima Y; Ikeda H; Imai N; Ogasawara K; Okumura K; Thomas DM; Smyth MJ, 2017, 'IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting', Nature Communications, vol. 8, http://dx.doi.org/10.1038/ncomms14607
    Journal articles | 2017
    Thomas DM, 2017, 'Is Li–Fraumeni syndrome really much more common?', Human Mutation, vol. 38, pp. 1619, http://dx.doi.org/10.1002/humu.23342
    Journal articles | 2017
    Thway K; Noujaim J; Thomas DM; Fisher C; Jones RL, 2017, 'Myoepithelial Carcinoma of the Paracecal Mesentery: Aggressive Behavior of a Rare Neoplasm at an Unusual Anatomic Site.', Rare Tumors, vol. 9, pp. 6504, http://dx.doi.org/10.4081/rt.2017.6504
    Journal articles | 2017
    Willis AM; Smith SK; Meiser B; Ballinger ML; Thomas DM; Young MA, 2017, 'Sociodemographic, psychosocial and clinical factors associated with uptake of genetic counselling for hereditary cancer: a systematic review', Clinical Genetics, vol. 92, pp. 121 - 133, http://dx.doi.org/10.1111/cge.12868
    Journal articles | 2016
    Ballinger ML; Goode DL; Ray-Coquard I; James PA; Mitchell G; Niedermayr E; Puri A; Schiffman JD; Dite GS; Cipponi A; Maki RG; Brohl AS; Myklebost O; Stratford EW; Lorenz S; Ahn SM; Ahn JH; Kim JE; Shanley S; Beshay V; Randall RL; Judson I; Seddon B; Campbell IG; Young MA; Sarin R; Blay JY; O'Donoghue SI; Thomas DM, 2016, 'Monogenic and polygenic determinants of sarcoma risk: an international genetic study', The Lancet Oncology, vol. 17, pp. 1261 - 1271, http://dx.doi.org/10.1016/S1470-2045(16)30147-4
    Journal articles | 2016
    Ballinger ML; Thomas DM, 2016, 'Sarcoma and germ-line DICER1 mutations – Authors’ reply', The Lancet Oncology, vol. 17, pp. e471, http://dx.doi.org/10.1016/S1470-2045(16)30527-7
    Journal articles | 2016
    Burgess A; Chia KM; Haupt S; Thomas D; Haupt Y; Lim E, 2016, 'Clinical overview of MDM2/X-targeted therapies', Frontiers in Oncology, vol. 6, http://dx.doi.org/10.3389/fonc.2016.00007
    Journal articles | 2016
    Gaston CL; Grimer RJ; Parry M; Stacchiotti S; Tos APD; Gelderblom H; Ferrari S; Baldi GG; Jones RL; Chawla S; Casali P; LeCesne A; Blay J-Y; Dijkstra SPD; Thomas DM; Rutkowski P, 2016, 'Current status and unanswered questions on the use of Denosumab in giant cell tumor of bone', CLINICAL SARCOMA RESEARCH, vol. 6, http://dx.doi.org/10.1186/s13569-016-0056-0
    Journal articles | 2016
    Kager L; Whelan J; Dirksen U; Hassan B; Anninga J; Bennister L; Bovee JVMG; Brennan B; Broto JM; Brugieres L; Cleton-Jansen A-M; Copland C; Dutour A; Fagioli F; Ferrari S; Fiocco M; Fleuren E; Gaspar N; Gelderblom H; Gerrand C; Gerss J; Gonzato O; van der Graaf W; Hecker-Nolting S; Herrero-Martin D; Klco-Brosius S; Kovar H; Ladenstein R; Lancia C; LeDeley M-C; McCabe MG; Metzler M; Myklebost O; Nathrath M; Picci P; Potratz J; Redini F; Richter GHS; Reinke D; Rutkowski P; Scotlandi K; Strauss S; Thomas D; Tirado OM; Tirode F; Vassal G; Bielack SS, 2016, 'The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report', CLINICAL SARCOMA RESEARCH, vol. 6, http://dx.doi.org/10.1186/s13569-016-0043-5
    Journal articles | 2016
    Lomax AJ; Beith J; Bhadri V; Boyer M; Grimison P; Horvath LG; Kao S; Tattersall M; Thomas D; McNeil C, 2016, 'Outcomes of patients with non-melanoma solid tumours receiving self-funded pembrolizumab at Chris O'Brien Lifehouse', Internal Medicine Journal, vol. 46, pp. 1392 - 1398, http://dx.doi.org/10.1111/imj.13232
    Journal articles | 2016
    Lorgelly PK; Doble B; Knott RJ; Thomas DM; Fox SB; Thorne H; Parisot JP; Doig K; Fellowes A; Dobrovic A; Lipton L; Ashley D; Hayes T; McMurrick P; Richardson G; Lucas M; McNeil JJ; John T, 2016, 'Realising the Value of Linked Data to Health Economic Analyses of Cancer Care: A Case Study of Cancer 2015', PharmacoEconomics, vol. 34, pp. 139 - 154, http://dx.doi.org/10.1007/s40273-015-0343-2
    Journal articles | 2016
    McBride KA; Hallowell N; Tattersall MHN; Kirk J; Ballinger ML; Thomas DM; Mitchell G; Young MA, 2016, 'Timing and context: important considerations in the return of genetic results to research participants', Journal of Community Genetics, vol. 7, pp. 11 - 20, http://dx.doi.org/10.1007/s12687-015-0231-7
    Journal articles | 2016
    Ngiow SF; Loi S; Thomas D; Smyth MJ, 2016, 'Mouse Models of Tumor Immunotherapy', Tumor immunology, vol. 130, pp. 1 - 24, http://dx.doi.org/10.1016/bs.ai.2015.12.004
    Journal articles | 2016
    Thomas D, 2016, 'International survey of awareness of genetic risk in the clinical sarcoma community', Asia Pac J Clin Oncol, vol. 12, pp. 133 - 142, http://dx.doi.org/10.1111/ajco.12457
    Journal articles | 2016
    Thomas DM; Ballinger ML, 2016, 'Diagnosis and management of hereditary sarcoma', Recent Results in Cancer Research, vol. 205, pp. 169 - 189, http://dx.doi.org/10.1007/978-3-319-29998-3_10
    Journal articles | 2016
    Vargas AC; Selinger CI; Satgunaseelan L; Cooper WA; Gupta R; Stalley P; Brown W; Soper J; Schatz J; Boyle R; Thomas DM; Tattersall MHN; Bhadri VA; Maclean F; Bonar SF; Scolyer RA; Karim RZ; McCarthy SW; Mahar A; O'Toole SA, 2016, 'Atypical Ewing sarcoma breakpoint region 1 fluorescence in-situ hybridization signal patterns in bone and soft tissue tumours: diagnostic experience with 135 cases', Histopathology, vol. 69, pp. 1000 - 1011, http://dx.doi.org/10.1111/his.13031
    Journal articles | 2015
    Ashley D; Thomas D; Gore L; Carter R; Zalcberg JR; Otmar R; Savulescu J, 2015, 'Accepting risk in the acceleration of drug development for rare cancers', The Lancet Oncology, vol. 16, pp. e190 - e194, http://dx.doi.org/10.1016/S1470-2045(14)71153-2
    Journal articles | 2015
    Ballinger ML; Mitchell G; Thomas DM, 2015, 'Surveillance recommendations for patients with germline TP53 mutations', Current Opinion in Oncology, vol. 27, pp. 332 - 337, http://dx.doi.org/10.1097/CCO.0000000000000200
    Journal articles | 2015
    Chantrill LA; Nagrial AM; Watson C; Johns AL; Martyn-Smith M; Simpson S; Mead S; Jones MD; Samra JS; Gill AJ; Watson N; Chin VT; Humphris JL; Chou A; Brown B; Morey A; Pajic M; Grimmond SM; Chang DK; Thomas D; Sebastian L; Sjoquist K; Yip S; Pavlakis N; Asghari R; Harvey S; Grimison P; Simes J; Biankin AV, 2015, 'Precision medicine for advanced pancreas cancer: The individualized molecular pancreatic cancer therapy (IMPaCT) Trial', Clinical Cancer Research, vol. 21, pp. 2029 - 2037, http://dx.doi.org/10.1158/1078-0432.CCR-15-0426
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    Martin JH; Phillips E; Thomas D; Somogyi AA, 2015, 'Adding the 'medicines' back into personalized medicine to improve cancer treatment outcomes', British Journal of Clinical Pharmacology, vol. 80, pp. 929 - 931, http://dx.doi.org/10.1111/bcp.12690
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    Mirabello L; Koster R; Moriarity BS; Spector LG; Meltzer PS; Gary J; Machiela MJ; Pankratz N; Panagiotou OA; Largaespada D; Wang Z; Gastier-Foster JM; Gorlick R; Khanna C; de Toledo SRC; Petrilli AS; Patiño-Garcia A; Sierrasesúmaga L; Lecanda F; Andrulis IL; Wunder JS; Gokgoz N; Serra M; Hattinger C; Picci P; Scotlandi K; Flanagan AM; Tirabosco R; Amary MF; Halai D; Ballinger ML; Thomas DM; Davis S; Barkauskas DA; Marina N; Helman L; Otto GM; Becklin KL; Wolf NK; Weg MT; Tucker M; Wacholder S; Fraumeni JF; Caporaso NE; Boland JF; Hicks BD; Vogt A; Burdett L; Yeager M; Hoover RN; Chanock SJ; Savage SA, 2015, 'A genome-wide scan identifies variants in NFIB associated with metastasis in patients with osteosarcoma', Cancer Discovery, vol. 5, pp. 920 - 931, http://dx.doi.org/10.1158/2159-8290.CD-15-0125
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    Neuhaus SJ; Thomas D; Desai J; Vuletich C; Von Dincklage J; Olver I, 2015, 'Wiki-based clinical practice guidelines for the management of adult onset sarcoma: A new paradigm in sarcoma evidence', Sarcoma, vol. 2015, http://dx.doi.org/10.1155/2015/614179
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    Papenfuss AT; Thomas DM, 2015, 'The life history of neochromosomes revealed', Molecular and Cellular Oncology, vol. 2, pp. e1000698, http://dx.doi.org/10.1080/23723556.2014.1000698
    Journal articles | 2015
    Parisot JP; Thorne H; Fellowes A; Doig K; Lucas M; McNeil JJ; Doble B; Dobrovic A; John T; James PA; Lipton L; Ashley D; Hayes T; McMurrick P; Richardson G; Lorgelly P; Fox SB; Thomas DM, 2015, '“Cancer 2015”: A prospective, population-based cancer cohort—phase 1: Feasibility of genomics-guided precision medicine in the clinic', Journal of Personalized Medicine, vol. 5, pp. 354 - 369, http://dx.doi.org/10.3390/jpm5040354
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    Tattersall MHN; Thomas DM, 2015, 'Distinguishing activity from progress', The Lancet Oncology, vol. 16, pp. 1586 - 1588, http://dx.doi.org/10.1016/S1470-2045(15)00466-0
    Journal articles | 2015
    Thomas DM, 2015, 'The growing problem of benign connective tissue tumours', The Lancet Oncology, vol. 16, pp. 879 - 880, http://dx.doi.org/10.1016/S1470-2045(15)00147-3
    Journal articles | 2015
    Thomas DM; Ballinger ML, 2015, 'Etiologic, environmental and inherited risk factors in sarcomas', Journal of Surgical Oncology, vol. 111, pp. 490 - 495, http://dx.doi.org/10.1002/jso.23809
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    Thomas DM; Fox S; Lorgelly PK; Ashley D; Richardson G; Lipton L; Parisot JP; Lucas M; McNeil J, 2015, 'Cancer 2015: A longitudinal whole-of-system study of genomic cancer medicine', Drug Discovery Today, vol. 20, pp. 1429 - 1432, http://dx.doi.org/10.1016/j.drudis.2015.10.009
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    Thomas DM; James PA; Ballinger ML, 2015, 'Clinical implications of genomics for cancer risk genetics', The Lancet Oncology, vol. 16, pp. e303 - e308, http://dx.doi.org/10.1016/S1470-2045(15)70026-4
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    Thomas DM; Wood MA, 2015, 'THE EMERGENCE OF NEGATIVE SUPERHUMPS IN CATACLYSMIC VARIABLES: SMOOTHED PARTICLE HYDRODYNAMICS SIMULATIONS', ASTROPHYSICAL JOURNAL, vol. 803, http://dx.doi.org/10.1088/0004-637X/803/2/55
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    Wong SQ; Fellowes A; Doig K; Ellul J; Bosma TJ; Irwin D; Vedururu R; Tan AYC; Weiss J; Chan KS; Lucas M; Thomas DM; Dobrovic A; Parisot JP; Fox SB, 2015, 'Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients', British Journal of Cancer, vol. 112, pp. 1411 - 1420, http://dx.doi.org/10.1038/bjc.2015.80
    Journal articles | 2014
    Anninga JK; Cleton-Jansen A-M; Hassan B; Amary MF; Baumhoer D; Blay J-Y; Brugieres L; Ferrari S; Jurgens H; Kempf-Bielack B; Kovar H; Myklebost O; Nathrath M; Picci P; Riegman P; Schilham MW; Soliman R; Stark DP; Strauss S; Sydes M; Tarpey P; Thomas D; Whelan J; Wilhelm M; Zamzam M; Gelderblom H; Bielack SS, 2014, 'Workshop report on the 2nd Joint ENCCA/EuroSARC European bone sarcoma network meeting: integration of clinical trials with tumour biology', CLINICAL SARCOMA RESEARCH, vol. 4, http://dx.doi.org/10.1186/2045-3329-4-4
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    Cipponi A; Thomas DM, 2014, 'Stress-induced cellular adaptive strategies: Ancient evolutionarily conserved programs as new anticancer therapeutic targets', BioEssays, vol. 36, pp. 552 - 560, http://dx.doi.org/10.1002/bies.201300170
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    Garsed DW; Marshall OJ; Corbin VDA; Hsu A; DiStefano L; Schröder J; Li J; Feng ZP; Kim BW; Kowarsky M; Lansdell B; Brookwell R; Myklebost O; Meza-Zepeda L; Holloway AJ; Pedeutour F; Choo KHA; Damore MA; Deans AJ; Papenfuss AT; Thomas DM, 2014, 'The Architecture and Evolution of Cancer Neochromosomes', Cancer Cell, vol. 26, pp. 653 - 667, http://dx.doi.org/10.1016/j.ccell.2014.09.010
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    Kansara M; Teng MW; Smyth MJ; Thomas DM, 2014, 'Translational biology of osteosarcoma', Nature Reviews Cancer, vol. 14, pp. 722 - 735, http://dx.doi.org/10.1038/nrc3838
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    Kansara M; Thomas DM, 2014, 'RB1-mediated cell-autonomous and hostdependent oncosuppressor mechanisms in radiation-induced osteosarcoma', OncoImmunology, vol. 3, http://dx.doi.org/10.4161/onci.27569
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    Lewin J; Khamly KK; Young RJ; Mitchell C; Hicks RJ; Toner GC; Ngan SYK; Chander S; Powell GJ; Herschtal A; Te Marvelde L; Desai J; Choong PFM; Stacker SA; Achen MG; Ferris N; Fox S; Slavin J; Thomas DM, 2014, 'A phase Ib/II translational study of sunitinib with neoadjuvant radiotherapy in soft-tissue sarcoma', British Journal of Cancer, vol. 111, pp. 2254 - 2261, http://dx.doi.org/10.1038/bjc.2014.537
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    McBride KA; Ballinger ML; Killick E; Kirk J; Tattersall MHN; Eeles RA; Thomas DM; Mitchell G, 2014, 'Li-Fraumeni syndrome: Cancer risk assessment and clinical management', Nature Reviews Clinical Oncology, vol. 11, pp. 260 - 271, http://dx.doi.org/10.1038/nrclinonc.2014.41
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    Pishas KI; Neuhaus SJ; Clayer MT; Schreiber AW; Lawrence DM; Perugini M; Whitfield RJ; Farshid G; Manavis J; Chryssidis S; Mayo BJ; Haycox RC; Ho K; Brown MP; D'Andrea RJ; Evdokiou A; Thomas DM; Desai J; Callen DF; Neilsen PM, 2014, 'Nutlin-3a efficacy in sarcoma predicted by transcriptomic and epigenetic profiling', Cancer Research, vol. 74, pp. 921 - 931, http://dx.doi.org/10.1158/0008-5472.CAN-13-2424
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    Wang Z; Zhu B; Zhang M; Parikh H; Jia J; Chung CC; Sampson JN; Hoskins JW; Hutchinson A; Burdette L; Ibrahim A; Hautman C; Raj PS; Abnet CC; Adjei AA; Ahlbom A; Albanes D; Allen NE; Ambrosone CB; Aldrich M; Amiano P; Amos C; Andersson U; Gerald Andriole GA; Andrulis IL; Arici C; Arslan AA; Austin MA; Baris D; Barkauskas DA; Bassig BA; Freeman LEB; Berg CD; Berndt SI; Bertazzi PA; Biritwum RB; Black A; Blot W; Boeing H; Boffetta P; Bolton K; Boutron-Ruault MC; Bracci PM; Brennan P; Brinton LA; Brotzman M; Bueno-de-Mesquita HB; Buring JE; Butler MA; Cai Q; Cancel-Tassin G; Canzian F; Cao G; Caporaso NE; Carrato A; Carreon T; Carta A; Chang GC; Chang IS; Chang-Claude J; Che X; Chen CJ; Chen CY; Chen CH; Chen C; Chen KY; Chen YM; Chokkalingam AP; Chu LW; Clavel-Chapelon F; Colditz GA; Colt JS; Conti D; Cook MB; Cortessis VK; Crawford ED; Cussenot O; Davis FG; De Vivo I; Deng X; Ding T; Dinney CP; Di Stefano AL; Diver WR; Duell EJ; Elena JW; Fan JH; Feigelson HS; Feychting M; Figueroa JD; Flanagan AM; Fraumeni JF; Freedman ND; Fridley BL; Fuchs CS; Gago-Dominguez M; Gallinger S; Gao YT; Gapstur SM; Garcia-Closas M, 2014, 'Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33', Human Molecular Genetics, vol. 23, pp. 6616 - 6633, http://dx.doi.org/10.1093/hmg/ddu363
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    Wong SQ; Li J; Tan AYC; Vedururu R; Pang JMB; Do H; Ellul J; Doig K; Bell A; Macarthur GA; Fox SB; Thomas DM; Fellowes A; Parisot JP; Dobrovic A, 2014, 'Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing', BMC Medical Genomics, vol. 7, http://dx.doi.org/10.1186/1755-8794-7-23
    Journal articles | 2013
    Bandopadhayay P; Jabbour AM; Riffkin C; Salmanidis M; Gordon L; Popovski D; Rigby L; Ashley DM; Watkins DN; Thomas DM; Algar E; Ekert PG, 2013, 'The oncogenic properties of EWS/WT1 of desmoplastic small round cell tumors are unmasked by loss of p53 in murine embryonic fibroblasts', BMC Cancer, vol. 13, http://dx.doi.org/10.1186/1471-2407-13-585
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    Cain JE; McCaw A; Jayasekara WSN; Rossello FJ; Marini KD; Irving AT; Kansara M; Thomas DM; Ashley DM; Watkins DN, 2013, 'Sustained low-dose treatment with the Histone deacetylase inhibitor LBH589 induces terminal differentiation of osteosarcoma cells', Sarcoma, vol. 2013, http://dx.doi.org/10.1155/2013/608964
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    Chawla S; Henshaw R; Seeger L; Choy E; Blay JY; Ferrari S; Kroep J; Grimer R; Reichardt P; Rutkowski P; Schuetze S; Skubitz K; Staddon A; Thomas D; Qian Y; Jacobs I, 2013, 'Safety and efficacy of denosumab for adults and skeletally mature adolescents with giant cell tumour of bone: Interim analysis of an open-label, parallel-group, phase 2 study', The Lancet Oncology, vol. 14, pp. 901 - 908, http://dx.doi.org/10.1016/S1470-2045(13)70277-8
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    Collins M; Wilhelm M; Conyers R; Herschtal A; Whelan J; Bielack S; Kager L; Kühne T; Sydes M; Gelderblom H; Ferrari S; Picci P; Smeland S; Eriksson M; Petrilli AS; Bleyer A; Thomas DM, 2013, 'Benefits and adverse events in younger versus older patients receiving neoadjuvant chemotherapy for osteosarcoma: Findings from a meta-analysis', Journal of Clinical Oncology, vol. 31, pp. 2303 - 2312, http://dx.doi.org/10.1200/JCO.2012.43.8598
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    Doble B; Harris A; Thomas DM; Fox S; Lorgelly P, 2013, 'Multiomics medicine in oncology: Assessing effectiveness, cost-effectiveness and future research priorities for the molecularly unique individual', Pharmacogenomics, vol. 14, pp. 1405 - 1417, http://dx.doi.org/10.2217/pgs.13.142
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    Harvey KF; Zhang X; Thomas DM, 2013, 'The Hippo pathway and human cancer', Nature Reviews Cancer, vol. 13, pp. 246 - 257, http://dx.doi.org/10.1038/nrc3458
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    Kansara M; Leong HS; Lin DM; Popkiss S; Pang P; Garsed DW; Walkley CR; Cullinane C; Ellul J; Haynes NM; Hicks R; Kuijjer ML; Cleton-Jansen AM; Hinds PW; Smyth MJ; Thomas DM, 2013, 'Immune response to rb1-Regulated senescence limits radiation-Induced osteosarcoma formation', Journal of Clinical Investigation, vol. 123, pp. 5351 - 5360, http://dx.doi.org/10.1172/JCI70559
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    Lewin J; Puri A; Quek R; Ngan R; Alcasabas AP; Wood D; Thomas D, 2013, 'Management of sarcoma in the asia-pacific region: Resource-stratified guidelines', The Lancet Oncology, vol. 14, pp. e562 - e570, http://dx.doi.org/10.1016/S1470-2045(13)70475-3
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    Lewin J; Thomas D, 2013, 'Denosumab: A new treatment option for giant cell tumor of bone', Drugs of Today, vol. 49, pp. 693 - 700, http://dx.doi.org/10.1358/dot.2013.49.11.2064725
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    Lewin J; Wieringa S; Collins M; Desai J; Orme L; Lingaratnam S; Thomas DM, 2013, 'Intra-patient dose escalation in Ewing's sarcoma treated with vincristine, doxorubicin, cyclophosphamide alternating with ifosfamide and etoposide: a retrospective review', CLINICAL SARCOMA RESEARCH, vol. 3, http://dx.doi.org/10.1186/2045-3329-3-15
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    Mitchell G; Ballinger ML; Wong S; Hewitt C; James P; Young MA; Cipponi A; Pang T; Goode DL; Dobrovic A; Thomas DM; Porceddu S; Gattas M; Neuhaus S; Suthers G; Tattersall M; Tucker K; Lewis C; Carey-Smith R, 2013, 'High Frequency of Germline TP53 Mutations in a Prospective Adult-Onset Sarcoma Cohort', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0069026
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    Rossello FJ; Tothill RW; Britt K; Marini KD; Falzon J; Thomas DM; Peacock CD; Marchionni L; Li J; Bennett S; Tantoso E; Brown T; Chan P; Martelotto LG; Watkins DN, 2013, 'Next-Generation Sequence Analysis of Cancer Xenograft Models', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0074432
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    Savage SA; Mirabello L; Wang Z; Gastier-Foster JM; Gorlick R; Khanna C; Flanagan AM; Tirabosco R; Andrulis IL; Wunder JS; Gokgoz N; Patiño-Garcia A; Sierrasesúmaga L; Lecanda F; Kurucu N; Ilhan IE; Sari N; Serra M; Hattinger C; Picci P; Spector LG; Barkauskas DA; Marina N; De Toledo SRC; Petrilli AS; Amary MF; Halai D; Thomas DM; Douglass C; Meltzer PS; Jacobs K; Chung CC; Berndt SI; Purdue MP; Caporaso NE; Tucker M; Rothman N; Landi MT; Silverman DT; Kraft P; Hunter DJ; Malats N; Kogevinas M; Wacholder S; Troisi R; Helman L; Fraumeni JF; Yeager M; Hoover RN; Chanock SJ, 2013, 'Genome-wide association study identifies two susceptibility loci for osteosarcoma', Nature Genetics, vol. 45, pp. 799 - 803, http://dx.doi.org/10.1038/ng.2645
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    Tothill RW; Li J; Mileshkin L; Doig K; Siganakis T; Cowin P; Fellowes A; Semple T; Fox S; Byron K; Kowalczyk A; Thomas D; Schofield P; Bowtell DD, 2013, 'Massively-parallel sequencing assists the diagnosis and guided treatment of cancers of unknown primary', Journal of Pathology, vol. 231, pp. 413 - 423, http://dx.doi.org/10.1002/path.4251
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    Young M-A; Herlihy A; Mitchell G; Thomas DM; Ballinger M; Tucker K; Lewis CR; Neuhaus S; Halliday J, 2013, 'The attitudes of people with sarcoma and their family towards genomics and incidental information arising from genetic research', Clinical Sarcoma Research, vol. 3, pp. 11 - 11, http://dx.doi.org/10.1186/2045-3329-3-11
    Journal articles | 2012
    Angoa-Perez M; Kane MJ; Briggs DI; Sykes CE; Shah MM; Francescutti DM; Rosenberg DR; Thomas DM; Kuhn DM, 2012, 'Genetic depletion of brain 5HT reveals a common molecular pathway mediating compulsivity and impulsivity', JOURNAL OF NEUROCHEMISTRY, vol. 121, pp. 974 - 984, http://dx.doi.org/10.1111/j.1471-4159.2012.07739.x
    Journal articles | 2012
    Blay J; Chawla S; Choy E; Grimer RJ; Ferrari S; Reichardt P; Rutkowski P; Thomas D; Qian Y; Jacobs I, 2012, 'Efficacy and Safety of Denosumab in Giant Cell Tumor of Bone: Updated Results with Independent Radiographic Assessment of Response', Annals of Oncology, vol. 23, pp. ix479 - ix479, http://dx.doi.org/10.1016/s0923-7534(20)34053-9
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    Branstetter DG; Nelson SD; Manivel JC; Blay JY; Chawla S; Thomas DM; Jun S; Jacobs I, 2012, 'Denosumab induces tumor reduction and bone formation in patients with giant-cell tumor of bone', Clinical Cancer Research, vol. 18, pp. 4415 - 4424, http://dx.doi.org/10.1158/1078-0432.CCR-12-0578
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    Cassier PA; Gelderblom H; Stacchiotti S; Thomas D; Maki RG; Kroep JR; Van Der Graaf WT; Italiano A; Seddon B; Dômont J; Bompas E; Wagner AJ; Blay JY, 2012, 'Efficacy of imatinib mesylate for the treatment of locally advanced and/or metastatic tenosynovial giant cell tumor/pigmented villonodular synovitis', Cancer, vol. 118, pp. 1649 - 1655, http://dx.doi.org/10.1002/cncr.26409
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    Dyson GJ; Thompson K; Palmer S; Thomas DM; Schofield P, 2012, 'The relationship between unmet needs and distress amongst young people with cancer', Supportive Care in Cancer, vol. 20, pp. 75 - 85, http://dx.doi.org/10.1007/s00520-010-1059-7
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    Guagnano V; Kauffmann A; Wöhrle S; Stamm C; Ito M; Barys L; Pornon A; Yao Y; Li F; Zhang Y; Chen Z; Wilson CJ; Bordas V; Le Douget M; Alex Gaither L; Borawski J; Monahan JE; Venkatesan K; Brümmendorf T; Thomas DM; Garcia-Echeverria C; Hofmann F; Sellers WR; Graus-Porta D, 2012, 'FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a selective Pan-FGFR inhibitor', Cancer Discovery, vol. 2, pp. 1118 - 1133, http://dx.doi.org/10.1158/2159-8290.CD-12-0210
    Journal articles | 2012
    Hubbard J; Thomas DM; Yothers G; Green E; Blanke C; O'Connell MJ; Labianca R; Shi Q; Bleyer A; De Gramont A; Sargent D, 2012, 'Benefits and adverse events in younger versus older patients receiving adjuvant chemotherapy for colon cancer: Findings from the adjuvant colon cancer endpoints data set', Journal of Clinical Oncology, vol. 30, pp. 2334 - 2339, http://dx.doi.org/10.1200/JCO.2011.41.1975
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    Kelleher FC; Cain JE; Healy JM; Watkins DN; Thomas DM, 2012, 'Prevailing importance of the hedgehog signaling pathway and the potential for treatment advancement in sarcoma', Pharmacology and Therapeutics, vol. 136, pp. 153 - 168, http://dx.doi.org/10.1016/j.pharmthera.2012.08.004
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    Kelleher FC; Thomas DM, 2012, 'Molecular pathogenesis and targeted therapeutics in Ewing sarcoma/primitive neuroectodermal tumours', CLINICAL SARCOMA RESEARCH, vol. 2, http://dx.doi.org/10.1186/2045-3329-2-6
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    Lemech CR; Fontela A; Arkenau H-T; Chin MTM; Li S; Liauw WS; Thomas D; De Souza PL, 2012, 'Phase I study of everolimus in combination with fluvastatin and zoledronic acid in patients with solid tumours.', Journal of Clinical Oncology, vol. 30, pp. e13585 - e13585, http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e13585
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    Mahendran K; Ballinger M; Kirk J; Thomas D; Tattersall M, 2012, 'Pathogenic germline TP53 mutations in adult sarcoma patients; implications for treatment and screening – description of an upcoming project', Hereditary cancer in clinical practice, vol. 10, pp. A61 - A61, http://dx.doi.org/10.1186/1897-4287-10-s2-a61
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    Paget C; Duret H; Ngiow SF; Kansara M; Thomas DM; Smyth MJ, 2012, 'Studying the role of the immune system on the antitumor activity of a Hedgehog inhibitor against murine osteosarcoma', OncoImmunology, vol. 1, pp. 1313 - 1322, http://dx.doi.org/10.4161/onci.21680
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    Pedeutour F; Maire G; Pierron A; Thomas DM; Garsed DW; Bianchini L; Duranton-Tanneur V; Cortes-Maurel A; Italiano A; Squire JA; Coindre JM, 2012, 'A newly characterized human well-differentiated liposarcoma cell line contains amplifications of the 12q12-21 and 10p11-14 regions', Virchows Archiv, vol. 461, pp. 67 - 78, http://dx.doi.org/10.1007/s00428-012-1256-5
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    Ray-Coquard I; Thomas D, 2012, 'Targeted therapies: Pazopanib for soft-tissue sarcoma: A PALETTE of data emerges', Nature Reviews Clinical Oncology, vol. 9, pp. 431 - 432, http://dx.doi.org/10.1038/nrclinonc.2012.113
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    Thomas DM, 2012, 'RANKL, denosumab, and giant cell tumor of bone', Current Opinion in Oncology, vol. 24, pp. 397 - 403, http://dx.doi.org/10.1097/CCO.0b013e328354c129
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    Thomas DM; Ballinger ML, 2012, 'Inherited and de novo germline TP53 mutations in adult-onset sarcoma', Hereditary cancer in clinical practice, vol. 10, pp. A26 - A26, http://dx.doi.org/10.1186/1897-4287-10-s2-a26
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    Thomas DM; Ballinger ML, 2012, 'Inherited and de novo germline TP53 mutations in adult-onset sarcoma', Hereditary cancer in clinical practice, vol. 10, pp. A3 - A3, http://dx.doi.org/10.1186/1897-4287-10-s2-a3
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    Thomas DM; Savage SA; Bond GL, 2012, 'Hereditary and environmental epidemiology of sarcomas', CLINICAL SARCOMA RESEARCH, vol. 2, http://dx.doi.org/10.1186/2045-3329-2-13
    Journal articles | 2011
    Aubin S; Barr R; Rogers P; Schacter B; Bielack SS; Ferrari A; Manchester RA; McMaster K; Morgan S; Patterson M; Petrilli AS; Ribera J-M; Shaw P; Thomas DM; Treadgold C, 2011, 'What Should the Age Range Be for AYA Oncology?', JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY, vol. 1, pp. 3 - 10, http://dx.doi.org/10.1089/jayao.2011.1505
    Journal articles | 2011
    Blanke CD; Bot BM; Thomas DM; Bleyer A; Kohne CH; Seymour MT; De Gramont A; Goldberg RM; Sargent DJ, 2011, 'Impact of young age on treatment efficacy and safety in advanced colorectal cancer: A pooled analysis of patients from nine first-line phase III chemotherapy trials', Journal of Clinical Oncology, vol. 29, pp. 2781 - 2786, http://dx.doi.org/10.1200/JCO.2010.33.5281
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    Blay J; Chawla SP; Martin Broto J; Choy E; Dominkus M; Engellau J; Grimer R; Henshaw RM; Palmerini E; Reichardt P; Rutkowski P; Skubitz KM; Thomas DM; Zhao Y; Qian Y; Jacobs IA, 2011, 'Denosumab safety and efficacy in giant cell tumor of bone (GCTB): Interim results from a phase II study.', Journal of Clinical Oncology, vol. 29, pp. 10034 - 10034, http://dx.doi.org/10.1200/jco.2011.29.15_suppl.10034
    Journal articles | 2011
    Clark JCM; Akiyama T; Thomas DM; Labrinidis A; Evdokiou A; Galloway SJ; Kim HS; Dass CR; Choong PFM, 2011, 'RECK in osteosarcoma: A novel role in tumour vasculature and inhibition of tumorigenesis in an orthotopic model', Cancer, vol. 117, pp. 3517 - 3528, http://dx.doi.org/10.1002/cncr.25757
    Journal articles | 2011
    Collins IM; Thomas DM, 2011, 'Novel approaches to treatment of leiomyosarcomas', Current Oncology Reports, vol. 13, pp. 316 - 322, http://dx.doi.org/10.1007/s11912-011-0173-0
    Journal articles | 2011
    Hemmings C; Miles C; Slavin J; Bonar SF; Graf N; Austen L; Thomas D; Desai J; Barry P, 2011, 'Optimising the management of soft tissue tumours', Pathology, vol. 43, pp. 295 - 301, http://dx.doi.org/10.1097/PAT.0b013e3283464427
    Journal articles | 2011
    Ito M; Barys L; O'Reilly T; Young S; Gorbatcheva B; Monahan J; Zumstein-Mecker S; Choong PF; Dickinson I; Crowe P; Hemmings C; Desai J; Thomas DM; Lisztwan J, 2011, 'Comprehensive mapping of p53 pathway alterations reveals an apparent role for both SNP309 and MDM2 amplification in sarcomagenesis', Clinical Cancer Research, vol. 17, pp. 416 - 426, http://dx.doi.org/10.1158/1078-0432.CCR-10-2050
    Journal articles | 2011
    Kuhn DM; Angoa-Perez M; Thomas DM, 2011, 'Nucleus Accumbens Invulnerability to Methamphetamine Neurotoxicity', ILAR JOURNAL, vol. 52, pp. 352 - 365, http://dx.doi.org/10.1093/ilar.52.3.352
    Journal articles | 2011
    Lockwood WW; Stack D; Morris T; Grehan D; O'Keane C; Stewart GL; Cumiskey J; Lam WL; Squire JA; Thomas DM; O'Sullivan MJ, 2011, 'Cyclin E1 is amplified and overexpressed in osteosarcoma', Journal of Molecular Diagnostics, vol. 13, pp. 289 - 296, http://dx.doi.org/10.1016/j.jmoldx.2010.11.020
    Journal articles | 2011
    Neilsen PM; Pishas KI; Callen DF; Thomas DM, 2011, 'Targeting the p53 pathway in Ewing Sarcoma', Sarcoma, vol. 2011, http://dx.doi.org/10.1155/2011/746939
    Journal articles | 2011
    Newnham GM; Conron M; McLachlan SA; Dobrovic A; Do H; Li J; Opeskin K; Thompson N; Wright GM; Thomas DM, 2011, 'Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer', BMC Cancer, vol. 11, http://dx.doi.org/10.1186/1471-2407-11-93
    Journal articles | 2011
    Roudier M; Blay* JY; Chawla S; Manivel C; Nelson SD; Thomas D; Woody L; Soriano R; Jun S; Jacobs I, 2011, 'Denosumab decreases proliferation in giant cell tumor of bone (GCTB)', Bone, vol. 48, pp. S15 - S15, http://dx.doi.org/10.1016/j.bone.2010.10.039
    Journal articles | 2011
    Thomas D; Moore A, 2011, 'Counterpoints in cancer: The somatic mutation theory under attack', BioEssays, vol. 33, pp. 313 - 314, http://dx.doi.org/10.1002/bies.201190016
    Journal articles | 2011
    Thomas DM, 2011, 'Lessons from the deep study of rare tumours', Journal of Pathology, vol. 224, pp. 306 - 308, http://dx.doi.org/10.1002/path.2928
    Journal articles | 2011
    Thomas DM; Conyers R; Young S, 2011, 'Liposarcoma: Molecular genetics and therapeutics', Sarcoma, vol. 2011, http://dx.doi.org/10.1155/2011/483154
    Journal articles | 2011
    Thomas DM; Wilhelm M; Cleton-Jansen A-M; Dirksen U; Entz-Werle N; Gelderblom H; Hassan B; Juergens H; Koster J; Kovar H; Lankester AC; Lewis IJ; Myklebost O; Nathrath MHM; Picci P; Whelan JS; Hogendoorn PCW; Bielack SS, 2011, 'Workshop Report on the European Bone Sarcoma Networking Meeting: Integration of Clinical Trials with Tumor Biology', JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY, vol. 1, pp. 118 - 123, http://dx.doi.org/10.1089/jayao.2012.0005
    Journal articles | 2010
    Cassier PA; Stacchiotti S; Gelderblom H; Thomas DM; Van Der Graaf W; Seddon BM; Julien D; Wagner AJ; Blay J, 2010, 'Imatinib mesylate for the treatment of locally advanced and/or metastatic pigmented villonodular synovitis/tenosynovial giant cell tumor (PVNS/TGCT).', Journal of Clinical Oncology, vol. 28, pp. 10012 - 10012, http://dx.doi.org/10.1200/jco.2010.28.15_suppl.10012
    Journal articles | 2010
    Conyers R; Thomas D, 2010, 'Review of “Cancer - basic science and clinical aspects”', BioEssays, vol. 32, pp. 914 - 916, http://dx.doi.org/10.1002/bies.201000084
    Journal articles | 2010
    Ferrari A; Thomas D; Franklin ARK; Hayes-Lattin BM; Mascarin M; Van Der Graaf W; Albritton KH, 2010, 'Starting an Adolescent and Young Adult Program: Some success stories and some obstacles to overcome', Journal of Clinical Oncology, vol. 28, pp. 4850 - 4857, http://dx.doi.org/10.1200/JCO.2009.23.8097
    Journal articles | 2010
    Sargent DJ; Yothers GA; Green E; Blanke CD; O'Connell MJ; Labianca R; Bleyer A; De Gramont A; Thomas DM, 2010, 'Benefits and adverse events (AEs) in younger (Y) (age <50) versus older patients (pts) receiving adjuvant chemotherapy (AT) for colon cancer (CC): Findings from the 33,574 pt ACCENT dataset.', Journal of Clinical Oncology, vol. 28, pp. 3523 - 3523, http://dx.doi.org/10.1200/jco.2010.28.15_suppl.3523
    Journal articles | 2010
    Journal articles | 2010
    Thomas D, 2010, 'The hard and soft sides of cancer programming', BioEssays, vol. 32, pp. 837 - 838, http://dx.doi.org/10.1002/bies.201090036
    Journal articles | 2010
    Thomas D; Carriere P; Jacobs I, 2010, 'Safety of denosumab in giant-cell tumour of bone', The Lancet Oncology, vol. 11, pp. 815, http://dx.doi.org/10.1016/S1470-2045(10)70170-4
    Journal articles | 2010
    Thomas D; Henshaw R; Skubitz K; Chawla S; Staddon A; Blay JY; Roudier M; Smith J; Ye Z; Sohn W; Dansey R; Jun S, 2010, 'Denosumab in patients with giant-cell tumour of bone: an open-label, phase 2 study', The Lancet Oncology, vol. 11, pp. 275 - 280, http://dx.doi.org/10.1016/S1470-2045(10)70010-3
    Journal articles | 2010
    Thomas DM, 2010, 'Importance of molecular genetics of sarcomas', Cancer Forum, vol. 34, pp. 154 - 156
    Journal articles | 2010
    Thomas DM, 2010, 'The importance of molecular and anatomic pathology in cancer management', Pathology, vol. 42, pp. S12 - S12, http://dx.doi.org/10.1097/01268031-201042001-00014
    Journal articles | 2010
    Thomas DM, 2010, 'The importance of molecular and anatomic pathology in cancer management', Pathology, vol. 42, pp. S31 - S31, http://dx.doi.org/10.1097/01268031-201042001-00063
    Journal articles | 2010
    Thomas DM, 2010, 'Wnts, bone and cancer', Journal of Pathology, vol. 220, pp. 1 - 4, http://dx.doi.org/10.1002/path.2635
    Journal articles | 2010
    Thomas DM; Albritton KH; Ferrari A, 2010, 'Adolescent and young adult oncology: An emerging field', Journal of Clinical Oncology, vol. 28, pp. 4781 - 4782, http://dx.doi.org/10.1200/JCO.2010.30.5128
    Journal articles | 2010
    Thomas DM; Wagner AJ, 2010, 'Specific targets in sarcoma and developmental therapeutics', JNCCN Journal of the National Comprehensive Cancer Network, vol. 8, pp. 677 - 685, http://dx.doi.org/10.6004/jnccn.2010.0050
    Journal articles | 2009
    Fleming NI; Trivett MK; George J; Slavin JL; Murray WK; Moseley JM; Anderson RL; Thomas DM, 2009, 'Parathyroid hormone-related protein protects against mammary tumor emergence and is associated with monocyte infiltration in ductal carcinoma in situ (Cancer Research (2009) 69, (7473-7479))', Cancer Research, vol. 69, pp. 8832, http://dx.doi.org/10.1158/0008-5472.CAN-09-3870
    Journal articles | 2009
    Fleming NI; Trivett MK; George J; Slavin JL; Murray WK; Moseley JM; Anderson RL; Thomas DM, 2009, 'Parathyroid hormone-related protein protects against mammary tumor emergence and is associated with monocyte infiltration in ductal carcinoma in situ', Cancer Research, vol. 69, pp. 7473 - 7479, http://dx.doi.org/10.1158/0008-5472.CAN-09-0194
    Journal articles | 2009
    Garsed DW; Holloway AJ; Thomas DM, 2009, 'Cancer-associated neochromosomes: A novel mechanism of oncogenesis', BioEssays, vol. 31, pp. 1191 - 1200, http://dx.doi.org/10.1002/bies.200800208
    Journal articles | 2009
    Kansara M; Tsang M; Kodjabachian L; Sims NA; Trivett MK; Ehrich M; Dobrovic A; Slavin J; Choong PFM; Simmons PJ; Dawid IB; Thomas DM, 2009, 'Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice', Journal of Clinical Investigation, vol. 119, pp. 837 - 851, http://dx.doi.org/10.1172/JCI37175
    Journal articles | 2009
    Khamly KK; Thursfield VJ; Fay M; Desai J; Toner GC; Choong PFM; Ngan SYK; Powell GJ; Thomas DM, 2009, 'Gender-specific activity of chemotherapy correlates with outcomes in chemosensitive cancers of young adulthood', International Journal of Cancer, vol. 125, pp. 426 - 431, http://dx.doi.org/10.1002/ijc.24376
    Journal articles | 2009
    Pires de Camargo V; van de Rijn M; de Alava E; Madoz-Gúrpide J; Pilotti S; von Mehren M; Pedeutour F; Maki RG; Rutkowski P; Thomas DM, 2009, 'Other Targetable Sarcomas', Seminars in Oncology, vol. 36, pp. 358 - 371, http://dx.doi.org/10.1053/j.seminoncol.2009.06.008
    Journal articles | 2009
    Soliman H; Ferrari A; Thomas D, 2009, 'Sarcoma in the Young Adult Population: An International View', Seminars in Oncology, vol. 36, pp. 227 - 236, http://dx.doi.org/10.1053/j.seminoncol.2009.03.006
    Journal articles | 2009
    Thomas D; Whyte S; Choong P, 2009, 'Australian Sarcona Study Group: Development and outlook', Cancer Forum, vol. 33, pp. 25 - 28
    Journal articles | 2009
    Thomas DM; Chawla S; Skubitz K; Staddon A; Henshaw R; Blay J; Smith J; Ye Z; Roudier M; Jun S, 2009, 'Denosumab for the treatment of giant cell tumor (GCT) of bone: Final results from a proof-of-concept, phase II study', Journal of Clinical Oncology, vol. 27, pp. 10510 - 10510, http://dx.doi.org/10.1200/jco.2009.27.15_suppl.10510
    Journal articles | 2009
    Thomas DM; O'Sullivan B; Gronchi A, 2009, 'Current concepts and future perspectives in retroperitoneal soft-tissue sarcoma management', Expert Review of Anticancer Therapy, vol. 9, pp. 1145 - 1157, http://dx.doi.org/10.1586/ERA.09.77
    Journal articles | 2009
    Thomas DM; Skubitz KM, 2009, 'Giant cell tumour of bone', Current Opinion in Oncology, vol. 21, pp. 338 - 344, http://dx.doi.org/10.1097/CCO.0b013e32832c951d
    Journal articles | 2008
    Alvaro F; Young A; Goldstein D; Thomas D; McJannett M; Dillon R, 2008, 'Clinical oncological society of Australia: Adolescent and young adult cancer forum', Cancer Forum, vol. 32, pp. 116 - 119
    Journal articles | 2008
    Bleyer A; Barr R; Hayes-Lattin B; Thomas D; Ellis C; Anderson B, 2008, 'The distinctive biology of cancer in adolescents and young adults', Nature Reviews Cancer, vol. 8, pp. 288 - 298, http://dx.doi.org/10.1038/nrc2349
    Journal articles | 2008
    Gutierrez GM; Kong E; Sabbagh Y; Brown NE; Lee JS; Demay MB; Thomas DM; Hinds PW, 2008, 'Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice', Proceedings of the National Academy of Sciences of the United States of America, vol. 105, pp. 18402 - 18407, http://dx.doi.org/10.1073/pnas.0805925105
    Journal articles | 2008
    Khamly KK; Hicks RJ; McArthur GA; Thomas DM, 2008, 'The promise of PET in clinical management and as a sensitive test for drug cytotoxicity in sarcomas', Expert Review of Molecular Diagnostics, vol. 8, pp. 105 - 119, http://dx.doi.org/10.1586/14737159.8.1.105
    Journal articles | 2008
    Newnham GM; Thomas DM; McLachlan SA; Wright G; Conron M, 2008, 'Molecular Profiling of Non-Small Cell Lung Cancer: Of What Value in Clinical Practice?', Heart Lung and Circulation, vol. 17, pp. 451 - 462, http://dx.doi.org/10.1016/j.hlc.2007.11.144
    Journal articles | 2008
    Thomas D; Chawla SP; Skubitz K; Staddon AP; Henshaw R; Blay JY; Smith J; Ye Z; Roudier M; Jun S, 2008, 'Denosumab treatment of giant cell tumor of bone: Interim analysis of an open-label phase II study', Journal of Clinical Oncology, vol. 26, pp. 10500 - 10500, http://dx.doi.org/10.1200/jco.2008.26.15_suppl.10500
    Journal articles | 2008
    Thomas DM; Francescutti-Verbeem DM; Kuhn DM, 2008, 'The newly synthesized pool of dopamine determines the severity of methamphetamine-induced neurotoxicity', JOURNAL OF NEUROCHEMISTRY, vol. 105, pp. 605 - 616, http://dx.doi.org/10.1111/j.1471-4159.2007.05155.x
    Journal articles | 2007
    Clark JCM; Thomas DM; Choong PFM; Dass CR, 2007, 'RECK - A newly discovered inhibitor of metastasis with prognostic significance in multiple forms of cancer', Cancer and Metastasis Reviews, vol. 26, pp. 675 - 683, http://dx.doi.org/10.1007/s10555-007-9093-8
    Journal articles | 2007
    Fon A; Mileshkin L; Slavin J; Twomey H; James P; Thomas DM, 2007, 'Synchronous diagnosis of Hodgkin lymphoma and osteosarcoma [1]', Internal Medicine Journal, vol. 37, pp. 731 - 732, http://dx.doi.org/10.1111/j.1445-5994.2007.01465.x
    Journal articles | 2007
    Kansara M; Thomas DM, 2007, 'Molecular pathogenesis of osteosarcoma', DNA and Cell Biology, vol. 26, pp. 1 - 18, http://dx.doi.org/10.1089/dna.2006.0505
    Journal articles | 2007
    Thomas DM, 2007, 'Adolescents and young adults with cancer: The challenge', Palliative and Supportive Care, vol. 5, pp. 173 - 174, http://dx.doi.org/10.1017/S1478951507070253
    Journal articles | 2006
    Amukotuwa SA; Choong PFM; Smith PJ; Powell GJ; Thomas D; Schlicht SM, 2006, 'Femoral mesenchymal chondrosarcoma with secondary aneurysmal bone cysts mimicking a small-cell osteosarcoma', Skeletal Radiology, vol. 35, pp. 311 - 318, http://dx.doi.org/10.1007/s00256-005-0044-6
    Journal articles | 2006
    Chaffer CL; Thomas DM; Thompson EW; Williams ED, 2006, 'PPARγ-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma', BMC Cancer, vol. 6, http://dx.doi.org/10.1186/1471-2407-6-53
    Journal articles | 2006
    Krypuy M; Newnham GM; Thomas DM; Conron M; Dobrovic A, 2006, 'High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer', BMC Cancer, vol. 6, http://dx.doi.org/10.1186/1471-2407-6-295
    Journal articles | 2006
    Lee JS; Thomas DM; Gutierrez G; Carty SA; Yanagawa SI; Hinds PW, 2006, 'HES1 cooperates with pRb to activate RUNX2-dependent transcription', Journal of Bone and Mineral Research, vol. 21, pp. 921 - 933, http://dx.doi.org/10.1359/jbmr.060303
    Journal articles | 2006
    Slavin JL; Thomas D, 2006, 'Gene expression profiling of sarcomas', Pathology, vol. 38, pp. 101 - 102, http://dx.doi.org/10.1080/00313020600595854
    Journal articles | 2006
    Tan JZY; Schlicht SM; Powell GJ; Thomas D; Slavin JL; Smith PJ; Choong PFM, 2006, 'Multidisciplinary approach to diagnosis and management of osteosarcoma - A review of the St Vincent's Hospital experience', International Seminars in Surgical Oncology, vol. 3, http://dx.doi.org/10.1186/1477-7800-3-38
    Journal articles | 2006
    Thomas D; Kansara M, 2006, 'Epigenetic modifications in osteogenic differentiation and transformation', Journal of Cellular Biochemistry, vol. 98, pp. 757 - 769, http://dx.doi.org/10.1002/jcb.20850
    Journal articles | 2006
    Thomas DM; Seymour JF; O'Brien T; Sawyer SM; Ashley DM, 2006, 'Adolescent and young adult cancer: A revolution in evolution?', Internal Medicine Journal, vol. 36, pp. 302 - 307, http://dx.doi.org/10.1111/j.1445-5994.2006.01062.x
    Journal articles | 2005
    Cullinane C; Dorow DS; Kansara M; Conus N; Binns D; Hicks RJ; Ashman LK; McArthur GA; Thomas DM, 2005, 'An in vivo tumor model exploiting metabolic response as a biomarker for targeted drug development', Cancer Research, vol. 65, pp. 9633 - 9636, http://dx.doi.org/10.1158/0008-5472.CAN-05-2285
    Journal articles | 2005
    Dudley AC; Thomas D; Best J; Jenkins A, 2005, 'A VEGF/JAK2/STAT5 axis may partially mediate endothelial cell tolerance to hypoxia', Biochemical Journal, vol. 390, pp. 427 - 436, http://dx.doi.org/10.1042/BJ20050351
    Journal articles | 2005
    Morgan T; Atkins GJ; Trivett MK; Johnson SA; Kansara M; Schlicht SL; Slavin JL; Simmons P; Dickinson I; Powell G; Choong PFM; Holloway AJ; Thomas DM, 2005, 'Molecular profiling of giant cell tumor of bone and the osteoclastic localization of ligand for receptor activator of nuclear factor κB', American Journal of Pathology, vol. 167, pp. 117 - 128, http://dx.doi.org/10.1016/S0002-9440(10)62959-8
    Journal articles | 2005
    Thomas DM; Kuhn DM, 2005, 'Cyclooxygenase-2 is an obligatory factor in methamphetamine-induced neurotoxicity', JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 313, pp. 870 - 876, http://dx.doi.org/10.1124/jpet.104.080242
    Journal articles | 2004
    Dudley AC; Thomas D; Best J; Jenkins A, 2004, 'The STATs in cell stress-type responses', Cell Communication and Signaling, vol. 2, http://dx.doi.org/10.1186/1478-811X-2-8
    Journal articles | 2004
    Thomas DM; Fleming NI; Holloway AJ; Bowtell DDL, 2004, 'Molecular medicine: A clinician's primer on microarrays', Internal Medicine Journal, vol. 34, pp. 565 - 569, http://dx.doi.org/10.1111/j.1445-5994.2004.00680.x
    Journal articles | 2004
    Thomas DM; Johnson SA; Sims NA; Trivett MK; Slavin JL; Rubin BP; Waring P; McArthur GA; Walkley CR; Holloway AJ; Diyagama D; Grim JE; Clurman BE; Bowtell DDL; Lee JS; Gutierrez GM; Piscopo DM; Carty SA; Hinds PW, 2004, 'Terminal osteoblast differentiation, mediated by runx2 and p27 KIP1, is disrupted in osteosarcoma', Journal of Cell Biology, vol. 167, pp. 925 - 934, http://dx.doi.org/10.1083/jcb.200409187
    Journal articles | 2003
    Chin SL; Johnson SA; Quinn J; Mirosavljevic D; Price JT; Dudley AC; Thomas DM, 2003, 'A role for αV integrin subunit in TGF-β-stimulated osteoclastogenesis', Biochemical and Biophysical Research Communications, vol. 307, pp. 1051 - 1058, http://dx.doi.org/10.1016/S0006-291X(03)01294-4
    Journal articles | 2003
    Dudley A; Gilbert RE; Thomas D; Cox A; Price JT; Best J; Jenkins A, 2003, 'STI-571 inhibits in vitro angiogenesis', Biochemical and Biophysical Research Communications, vol. 310, pp. 135 - 142, http://dx.doi.org/10.1016/j.bbrc.2003.08.129
    Journal articles | 2003
    Dudley A; McKinstry W; Thomas D; Best J; Jenkins A, 2003, 'Removal of endotoxin by reverse phase HPLC abolishes anti-endothelial cell activity of bacterially expressed plasminogen kringle 5', BioTechniques, vol. 35, pp. 724 - 732, http://dx.doi.org/10.2144/03354st02
    Journal articles | 2003
    Thomas DM; Yang HS; Alexander K; Hinds PW, 2003, 'Role of the retinoblastoma protein in differentiation and senescence', Cancer Biology and Therapy, vol. 2, pp. 124 - 130, http://dx.doi.org/10.4161/cbt.2.2.235
    Journal articles | 2002
    Cook N; Thomas DM, 2002, 'Retrospective survey of unselected hospital patients with and without cancer comparing outcomes following venous thromboembolism', Internal Medicine Journal, vol. 32, pp. 437 - 444, http://dx.doi.org/10.1046/j.1445-5994.2002.00249.x
    Journal articles | 2001
    Rosenthal MA; Thomas D; Davis I; Toner G; Noordin N; Zalcberg J, 2001, 'Pilot study of oral eniluracil/5-FU in the palliation of hormone-refractory prostate cancer', Prostate Journal, vol. 3, pp. 30 - 35, http://dx.doi.org/10.1046/j.1525-1411.2001.003001030.x
    Journal articles | 2001
    Thomas DM; Carty SA; Piscopo DM; Lee JS; Wang WF; Forrester WC; Hinds PW, 2001, 'The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation', Molecular Cell, vol. 8, pp. 303 - 316, http://dx.doi.org/10.1016/S1097-2765(01)00327-6
    Journal articles | 1999
    Ebeling PR; Thomas DM; Erbas B; Hopper JL; Szer J; Grigg AP, 1999, 'Mechanisms of bone loss following allogeneic and autologous hemopoietic stem cell transplantation', Journal of Bone and Mineral Research, vol. 14, pp. 342 - 350, http://dx.doi.org/10.1359/jbmr.1999.14.3.342
    Journal articles | 1999
    Puche RC; Thomas DM; Udagawa N; Hards DK; Quinn JMW; Moseley JM; Findlay DM; Best JD, 1999, 'Letters to the editor (multiple letters).', Bone, vol. 25
    Journal articles | 1998
    Thomas DM; Mitchell PLR; Berlangieri SU; Tochon-Danguy H; Knight S; Clarke CP; Scott AM, 1998, 'Correction: Positron emission tomography in assessing response to neoadjuvant chemotherapy for non-small-cell lung cancer (Medical Journal of Australia (1998) 169 (227))', Medical Journal of Australia, vol. 169, pp. 344
    Journal articles | 1998
    Thomas DM; Mitchell PLR; Berlangieri SU; Tochon-Danguy H; Knight S; Clarke CP; Scott AM, 1998, 'Positron emission tomography in assessing response to neoadjuvant chemotherapy for non-small-cell lung cancer (vol 169, pg 227, 1998)', MEDICAL JOURNAL OF AUSTRALIA, vol. 169, pp. 344 - 344, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000076023200028&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1998
    Thomas DM; Mitchell PLR; Berlangieri SU; Tochon-Danguy H; Knight S; Clarke CP; Scott AM, 1998, 'Positron emission tomography in assessing response to neoadjuvant chemotherapy for non-small-cell lung cancer [1]', Medical Journal of Australia, vol. 169, pp. 227, http://dx.doi.org/10.5694/j.1326-5377.1998.tb140229.x
    Journal articles | 1998
    Thomas DM; Seymour JF; Szer J; Grigg AP; Basser RL; Green MD; Fox RM; Thomas DM, 1998, 'Progress in management of acute myeloid leukaemia (AML) in Australia since 1980: A single institution retrospective study', Australian and New Zealand Journal of Medicine, vol. 28, pp. 190 - 196, http://dx.doi.org/10.1111/j.1445-5994.1998.tb02968.x
    Journal articles | 1998
    Thomas DM; Udagawa N; Hards DK; Quinn JMW; Moseley JM; Findlay DM; Best JD, 1998, 'Insulin receptor expression in primary and cultured osteoclast-like cells', Bone, vol. 23, pp. 181 - 186, http://dx.doi.org/10.1016/S8756-3282(98)00095-7
    Journal articles | 1998
    Thomas DM; Zalcberg JR, 1998, '5-Fluorouracil: A pharmacological paradigm in the use of cytotoxics', Clinical and Experimental Pharmacology and Physiology, vol. 25, pp. 887 - 895, http://dx.doi.org/10.1111/j.1440-1681.1998.tb02339.x
    Journal articles | 1997
    Thomas DM; Ng KW; Best JD, 1997, 'Insulin and bone: A clinical and scientific review', Endocrinology and Metabolism, Supplement, vol. 4, pp. 5 - 17
    Journal articles | 1997
    Thomas DM; Seymour JF; Griffiths JD; Szer J; Grigg AP, 1997, 'Prolonged disease-free survival with specific re-induction therapy in acute myeloid leukaemia relapsing following bone marrow transplantation', Australian and New Zealand Journal of Medicine, vol. 27, pp. 712 - 713, http://dx.doi.org/10.1111/j.1445-5994.1997.tb01009.x
    Journal articles | 1996
    Thomas DM; Hards DK; Rogers SD; Ng KW; Best JD, 1996, 'Insulin receptor expression in bone', Journal of Bone and Mineral Research, vol. 11, pp. 1312 - 1320, http://dx.doi.org/10.1002/jbmr.5650110916
    Journal articles | 1996
    Thomas DM; Maher F; Rogers SD; Best JD, 1996, 'Expression and regulation by insulin of Glut 3 in UMR 106-01, a clonal rat osteosarcoma cell line', Biochemical and Biophysical Research Communications, vol. 218, pp. 789 - 793, http://dx.doi.org/10.1006/bbrc.1996.0140
    Journal articles | 1996
    Thomas DM; Rogers SD; Ng KW; Best JD, 1996, 'Dexamethasone modulates insulin receptor expression and subcellular distribution of the glucose transporter GLUT 1 in UMR 106-01, a clonal osteogenic sarcoma cell line', Journal of Molecular Endocrinology, vol. 17, pp. 7 - 17, http://dx.doi.org/10.1677/jme.0.0170007
    Journal articles | 1995
    Thomas DM; Rogers SD; Sleeman MW; Pasquini GM; Bringhurst FR; Ng KW; Zajac JD; Best JD, 1995, 'Modulation of glucose transport by parathyroid hormone and insulin in UMR 106-01, a clonal rat osteogenic sarcoma cell line', Journal of Molecular Endocrinology, vol. 14, pp. 263 - 275, http://dx.doi.org/10.1677/jme.0.0140263
  • Preprints | 2022
    Best M; Bartley N; Napier C; Fisher A; Ballinger M; Thomas D; Goldstein D; Tucker K; Biesecker B; Butow P, 2022, Return of comprehensive tumour genomic profiling results to advanced cancer patients: a qualitative study, http://dx.doi.org/10.21203/rs.3.rs-1190781/v1
    Preprints | 2022
    Thavaneswaran S; Lin FP; Kansara M; Grady JP; Espinoza D; Joshua AM; Grimison P; Craft P; Cosman R; Lee C; Harwood K; Chinchen S; Corpuz T; Ballinger M; Sebastian L; Simes J; Thomas D, 2022, A signal-seeking Phase II trial of Durvalumab and Tremelimumab Focused on Advanced, Rare and Less Common Cancers, http://dx.doi.org/10.1101/2022.06.30.22277092
    Conference Papers | 2022
    Thomas DM, 2022, 'Heritable defects in telomere and mitotic function selectively predispose to sarcomas', in CANCER SCIENCE, WILEY, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000778583800159&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2021
    Bartley N; Best MC; Biesecker BB; Fisher A; Goldstein D; Meiser B; Thomas DM; Ballinger ML; Butow P, 2021, 'Effectively communicating comprehensive tumour genomic profiling results: Mitigating uncertainty for advanced cancer patients', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 180 - 180, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000717281500295&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints | 2021
    Jadhao S; Davison C; Roulis EV; Lee S; Lacaze P; Riaz M; McNeil JJ; Thomas DM; Pecheniuk NM; Hyland CA; Flower RL; Nagaraj SH, 2021, Using Whole Genome Sequencing to Characterize Clinically Significant Blood Groups Among Healthy Older Australians, http://dx.doi.org/10.1101/2021.04.18.21255241
    Conference Papers | 2021
    Scott CL; Lim R; Kee D; Georgiou C; Caldwell R; Papadopoulos L; Krasovitsky MS; Tay R; Bourne A; Vandenberg C; Dall G; Shield-Artin K; Carmagnac A; Ratnayak G; Tram J; Zhou W; Bedo J; Penington J; Zhu L; Vissers J; Thomas D; Grimmond S; Wakefield M; Papenfuss T; Barke H; Goldstein D, 2021, 'Delivering personalized care and research for rare cancers in the increasingly genomic world?', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 92 - 92, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000717281500102&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2021
    Thavaneswaran S; Sebastian L; Finlayson S; Desai J; O'Byrne K; Harrup R; Ballinger ML; Lin F; Grady JP; Kansara M; Simes J; Leland SM; Jansen VM; Cavers AC; Thomas DM, 2021, 'CRESTONE: Clinical Study of REsponse to Seribantumab in Tumours with NEuregulin-1 (NRG1) Fusions: A phase 2 study of the anti-HER3 monoclonal antibody for advanced or metastatic solid tumours (MoST CRESTONE in Australia)', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 206 - 206, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000717281500346&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints | 2021
    Thavaneswaran S; Sebastian L; Kansara M; Ballinger M; Espinoza D; Lin F; Lee C; Sjoquist K; Grady J; Cowley M; Joshua A; Qiu M; Oakes S; Simes J; Thomas D, 2021, A Signal-seeking Phase Iia Trial of Palbociclib in Advanced Cancers With Cell Cycle Pathway Alterations – A Substudy of the Molecular Screening and Therapeutics (Most) Program, http://dx.doi.org/10.21203/rs.3.rs-254137/v1
    Conference Papers | 2021
    Thomas DM, 2021, 'MTOR signaling orchestrates stress-induced mutagenesis facilitating adaptive evolution in human cancers', in CANCER SCIENCE, WILEY, pp. 182 - 182, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000618060100103&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2021
    Vatter S; Schlub TE; Napier CE; Best MC; Bartley N; Juraskova I; Meiser B; Ballinger ML; Biesecker BB; Goldstein D; Thomas DM; Butow P, 2021, 'Psychological outcomes in advanced cancer patients after receiving genomic tumour profiling results', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 198 - 198, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000717281500332&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2020
    Best M; Butow P; Jacobs C; Juraskova I; Savard J; Meiser B; Goldstein D; Ballinger M; Bartley N; Napier C; Davies G; Thomas D; Tucker K; Schlub T; Newson AJ, 2020, 'Advanced cancer patient preferences for receiving molecular profiling results', in Psycho-Oncology, WILEY, Vol. 29, pp. 1533 - 1539, http://dx.doi.org/10.1002/pon.5446
    Conference Papers | 2020
    Butow P; Best M; Davies G; Schlub T; Napier C; Bartley N; Ballinger M; Juraskova I; Meiser B; Goldstein D; Biesecker B; Thomas D, 2020, 'Psychological impact of comprehensive genomic profiling results to advanced cancer patients', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 92 - 92, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000790145400077&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2020
    Butow P; Davies G; Napier C; Thomas DM; Bartley N; Goldstein D; Ballinger ML; Juraskova I; Schlub TE; Tucker K; Meiser B; Young M-A, 2020, 'Return of results after somatic tumor mutation profiling in advanced cancer: Psychological impacts.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, ELECTR NETWORK, Vol. 38, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), ELECTR NETWORK, 29 May 2020 - 31 May 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000560368301063&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2020
    Joshua AM; Prawira A; Thavaneswaran S; Cosman R; Lee CK; Sjoquist KM; Simes J; Thomas DM; Espinoza D; Sebastian L; Ballinger ML; Hague W; Chinchen S; Collignon E; Kansara M; Palacios T; Grady J; Barker H; Thornton K, 2020, 'A signal-seeking trial of olaparib and durvalumab in homologous repair-deficient tumors: A sub-study of the cancer molecular screening and therapeutics (MoST) program.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, ELECTR NETWORK, Vol. 38, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), ELECTR NETWORK, 29 May 2020 - 31 May 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000560368301329&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2020
    Kee D; Kondrashova O; Ananda S; Brown MP; Cohen PA; Dean A; Desai J; Fellowes A; Fox SB; Hadley A; Lindsay D; Mileshkin LR; O'Byrne KJ; Prall OWJ; Scott H; Thomas DM; Vines R; Waddell N; Papenfuss A; Scott CL, 2020, 'NOMINATOR: Feasibility of genomic testing of rare cancers to match cancer to treatment.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, ELECTR NETWORK, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), ELECTR NETWORK, 29 May 2020 - 31 May 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000560368300004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2020
    Kee D; Kondrashova O; Hadley A; Brown MP; Dean A; Rico GT; Cohen P; Mileshkin L; Ananda S; O'Byrne K; Lindsay D; Vines R; Fox S; Desai J; Thomas D; Waddell N; Fellowes A; Papenfuss T; Scott CL, 2020, 'Outcomes in rare cancer patients who underwent comprehensive genomic sequencing in the NOMINATOR study', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 70 - 70, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000790145400028&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints | 2020
    Minoche AE; Lundie B; Peters GB; Ohnesorg T; Pinese M; Thomas DM; Zankl A; Roscioli T; Schonrock N; Kummerfeld S; Burnett L; Dinger ME; Cowley MJ, 2020, ClinSV: Clinical grade structural and copy number variant detection from whole genome sequencing data, http://dx.doi.org/10.1101/2020.06.30.20143453
    Conference Abstracts | 2020
    Zaheed M; Tucker K; Ballinger ML; Thomas DM, 2020, 'Genotype and phenotype correlation of common cancer predisposition syndromes in sarcoma cases.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, ELECTR NETWORK, Vol. 38, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), ELECTR NETWORK, 29 May 2020 - 31 May 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000560368301047&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2019
    Ballinger ML; Pinese M; Thomas DM, 2019, 'Translating genomic risk into an early detection strategy for sarcoma', in Genes Chromosomes and Cancer, United States, pp. 130 - 136, United States, http://dx.doi.org/10.1002/gcc.22697
    Conference Papers | 2019
    Best M; Butow P; Jacobs C; Savard J; Biesecker B; Ballinger M; Bartley N; Davies G; Napier CE; Smit AE; Thomas D; Newson AJ, 2019, 'Who should access germline genome sequencing? A mixed methods study of patient views', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 92 - 93, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000493438400100&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Best MC; Davies G; Napier CE; Bartley N; Juraskova I; Meiser B; Ballinger ML; Thomas DM; Schlub TE; Butow P, 2019, 'Exploring knowledge and attitudes in cancer tumour genomic profiling', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, Vol. 15, pp. 194 - 195, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000493438400321&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints | 2019
    Shin SJ; Dodd E; Peng G; Bojadzieva J; Chen J; Amos C; Mai PL; Savage SA; Ballinger ML; Thomas DM; Yuan Y; Strong LC; Wang W, 2019, Risk of differential cancer types over age in families with Li-Fraumeni syndrome: a validation study using multi-center cohorts, http://dx.doi.org/10.1101/567727
    Conference Papers | 2019
    Shin SJ; Dodd E; Peng G; Bojadzieva J; Chen J; Ning J; Mai PL; Savage SA; Ballinger ML; Thomas DM; Yuan Y; Strong LC; Wang W, 2019, 'Abstract 2434: Characterizing age-of-onset of multiple primary cancers and specific cancer types in families with Li-Fraumeni syndrome', in Prevention, Early Detection, and Interception, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-2434
    Conference Papers | 2019
    Shin SJ; Dodd E; Peng G; Bojadzieva J; Chen J; Ning J; Mai PL; Savage SA; Ballinger ML; Thomas DM; Yuan Y; Strong LC; Wang W, 2019, 'Characterizing age-of-onset of multiple primary cancers and specific cancer types in families with Li-Fraumeni syndrome', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, GA, Atlanta, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), GA, Atlanta, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-2434
    Conference Abstracts | 2019
    Thavaneswaran S; Ballinger ML; Grady J; Cowley M; Joshua A; Sebastian L; Collignon E; Silvestri A; Kansara M; Pinese M; Sjoquist KM; Hague W; Lee CK; Simes J; Thomas DM, 2019, 'The Cancer Molecular Screening and Therapeutics Program (MoST): Actionable mutation frequencies in a population with rare and less common cancers.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, Vol. 37, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2019 - 04 June 2019, http://dx.doi.org/10.1200/JCO.2019.37.15_suppl.3136
    Conference Abstracts | 2019
    Thavaneswaran S; Napier C; Goldstein D; Meiser B; Butow P; Thomas DM; Ballinger ML; Best M, 2019, 'Medical oncologists' experience with returning molecular tumor profiling to patients.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, Vol. 37, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2019 - 04 June 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000487345804031&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Barnet M; Jackson K; Gao B; Nagrial A; Boyer M; Cooper W; Hui R; Linton A; Tattersall M; Russell A; Gibson G; Cebon J; Long G; Menzies A; Scolyer R; Lacaze P; Brink R; Peters T; Cowley M; Gayevskiy V; Thomas D; Pinese M; Blinman P; Kao S; Goodnow C, 2018, 'Exploring the Germ-Line Contribution to Exceptional Response to PD-1/PD-L1 Inhibition in Patients with NSCLC by Whole Genome Sequencing', in JOURNAL OF THORACIC ONCOLOGY, ELSEVIER SCIENCE INC, Vol. 13, pp. S529 - S529, http://dx.doi.org/10.1016/j.jtho.2018.08.726
    Conference Papers | 2018
    Barnet MB; Jackson KJ; Gao B; Nagrial AM; Boyer MJ; Cooper WA; Hui R; Linton A; Tattersall MH; Gibson G; Cebon J; Long GV; Menzies AM; Scolyer RA; Lacaze P; Brink R; Peters T; Cowley M; Gayevskiy V; Thomas DM; Pinese M; Blinman P; Kao S; Goodnow CC, 2018, 'Exploring the germ-line contribution to exceptional response to PD-1/PD-L1 inhibition in patients with metastatic non-small-cell lung cancer by whole genome sequencing', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, IL, Chicago, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), IL, Chicago, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-LB-121
    Conference Papers | 2018
    Best M; Bartley N; Jacobs C; Juraskova I; Newson A; Savard J; Meiser B; Ballinger M; Thomas D; Biesecker B; Butow P, 2018, 'Advanced cancer patient perspectives on consenting to molecular tumour profiling: A qualitative study', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 144 - 144, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449544200232&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2018
    Best M; Bartley N; Jacobs C; Juraskova I; Newson A; Savard J; Meiser B; Ballinger M; Thomas D; Biesecker B; Butow P, 2018, 'Young cancer patient perspectives on undertaking whole genome sequencing: A qualitative study', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 144 - 144, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449544200231&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2018
    Cain JE; Cochrane CR; Vaghjiani V; Szczepny A; Mccaw A; Carey K; Martelotto L; Kansara M; Thomas D; Walkley C; Matsui WH; Watkins DN, 2018, 'p53 and RB regulate Hedgehog responsiveness via autophagy-mediated ciliogenesis', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, IL, Chicago, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), IL, Chicago, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-4994
    Conference Papers | 2018
    Dancsok AR; Thomas D; Blay J-Y; Maki RG; Nielsen TO; Demicco EG, 2018, 'Abstract B32: Lymphocytes and immune checkpoint biomarker expression in sarcomas', in Clinical Cancer Research, American Association for Cancer Research (AACR), pp. B32 - B32, presented at Abstracts: Advances in Sarcomas: From Basic Science to Clinical Translation; May 16-19, 2017; Philadelphia, PA, http://dx.doi.org/10.1158/1557-3265.sarcomas17-b32
    Conference Papers | 2018
    Ishaque S; Roberts R; Karnon J; Thomas D; Salter A, 2018, 'Adaptation/ content validation of measure yourself medical outcomes profile (MYMOP) questionnaire for 7-11 year old children', in QUALITY OF LIFE RESEARCH, SPRINGER, pp. S114 - S115, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000445248500282&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2018
    Kansara M; Pang P; Sulkowski N; Teng M; Smyth M; Thomas D, 2018, 'Abstract PR13: Pivotal role of interleukin 23 in osteosarcoma development and its link with glutamate metabotropic 4: Identification of novel therapeutic targets for osteosarcoma', in Clinical Cancer Research, American Association for Cancer Research (AACR), pp. PR13 - PR13, presented at Abstracts: Advances in Sarcomas: From Basic Science to Clinical Translation; May 16-19, 2017; Philadelphia, PA, http://dx.doi.org/10.1158/1557-3265.sarcomas17-pr13
    Conference Papers | 2018
    Koster R; Panagiotou OA; Wheeler WA; Karlins E; Gastier-Foster JM; Caminada de Toledo SR; Petrilli AS; Flanagan AM; Tirabosco R; Andrulis IL; Wunder JS; Gokgoz N; Patino-Garcia A; Lecanda F; Serra M; Hattinger C; Picci P; Scotlandi K; Thomas DM; Ballinger ML; Gorlick R; Barkauskas DA; Spector LG; Tucker M; Hicks B; Yeager M; Hoover R; Chanock SJ; Savage SA; Mirabello LJ, 2018, 'Genome-wide association study identifies the GLDC/IL33 locus associated with survival of osteosarcoma patients', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, IL, Chicago, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), IL, Chicago, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-2077
    Preprints | 2018
    Lacaze P; Pinese M; Kaplan W; Stone A; Brion M-J; Woods RL; McNamara M; McNeil JJ; Dinger ME; Thomas DM, 2018, The Medical Genome Reference Bank: a whole-genome data resource of 4,000 healthy elderly individuals. Rationale and cohort design, http://dx.doi.org/10.1101/274019
    Conference Papers | 2018
    Pinese M; Ballinger M; Thomas D, 2018, 'Abstract IA03: Translating genomic risk into an early detection strategy for sarcoma', in Clinical Cancer Research, American Association for Cancer Research (AACR), pp. IA03 - IA03, presented at Abstracts: Advances in Sarcomas: From Basic Science to Clinical Translation; May 16-19, 2017; Philadelphia, PA, http://dx.doi.org/10.1158/1557-3265.sarcomas17-ia03
    Conference Abstracts | 2018
    Thavaneswaran S; Sebastian L; Ballinger M; Cowley M; Grady J; Joshua A; Lee C; Sjoquist K; Hague W; Simes J; Thomas D, 2018, 'The cancer molecular screening and therapeutics program (MoST): A molecular screening platform with multiple, parallel, signal-seeking therapeutic substudies', in Annals of oncology : official journal of the European Society for Medical Oncology, OXFORD UNIV PRESS, Munich, GERMANY, Vol. 29, pp. viii147, presented at 43rd ESMO Congress (ESMO), Munich, GERMANY, 19 October 2018 - 23 October 2018, http://dx.doi.org/10.1093/annonc/mdy279.434
    Preprints | 2017
    Chan EKF; Petersen DC; Lyons RJ; Baldi BF; Papenfuss AT; Thomas DM; Hayes VM, 2017, Whole genome optical mapping reveals multiple fusion events chained by large novel sequences in cancer, http://dx.doi.org/10.1101/166173
    Conference Papers | 2017
    Dancsok AR; Thomas D; Blay J-Y; Maki RG; Nielsen TO; Demicco EG, 2017, 'Lymphocytes and immune checkpoint biomarker expression in sarcomas.', in CLINICAL CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, pp. 70 - 71, presented at AACR Special Conference on Advances in Sarcomas - From Basic Science to Clinical Translation, PA, Philadelphia, 16 May 2017 - 19 May 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000422882000095&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Posters | 2017
    Hess D; Sebastian LT; Sjoquist KM; Lee CK; Hague W; Miller D; Cowley M; Qiu MR; Fox SB; Joshua AM; Simes J; Thomas DM, 2017, 'The Molecular Screening and Therapeutics (MoST) Program: A precision medicine framework for biomarker-driven signal seeking clinical studies for rare cancers.', IL, Chicago, Vol. 35, presented at 53rd Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 02 June 2017 - 06 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.TPS2621
    Conference Papers | 2017
    Kansara M; Pang P; Sulkowski N; Teng M; Smyth M; Thomas D, 2017, 'Pivotal role of interleukin 23 in osteosarcoma development and its link with glutamate metabotropic 4: Identification of novel therapeutic targets for osteosarcoma.', in CLINICAL CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, pp. 33 - 34, presented at AACR Special Conference on Advances in Sarcomas - From Basic Science to Clinical Translation, PA, Philadelphia, 16 May 2017 - 19 May 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000422882000036&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2017
    Scheinberg T; Lomax A; Tattersall MHN; Thomas DM; McCowage GB; Sullivan MJ; Bhadri V, 2017, 'PD-1 blockade using pembrolizumab in adolescent and young adult patients with advanced bone and soft tissue sarcoma.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at 53rd Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 02 June 2017 - 06 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.3060
    Conference Abstracts | 2016
    Jones RM; Melton PE; Rea A; Ingley E; Ballinger ML; Wood DJ; Thomas DM; Moses EK, 2016, 'Whole Exome Sequencing in Multigenerational Mixed Cancer Families Identifies a Putative Risk Variant in the PDIA2 Gene', in GENETIC EPIDEMIOLOGY, WILEY-BLACKWELL, CANADA, Toronto, Vol. 40, pp. 644 - 644, presented at Annual Meeting of the International-Genetic-Epidemiology-Society, CANADA, Toronto, 24 October 2016 - 26 October 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000386034800102&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Posters | 2016
    McBride KA; Schlub TE; Ballinger ML; Thomas DM; Tattersall MHN, 2016, 'International survey of awareness of genetic risk in the clinical sarcoma community', Vol. 12, pp. 133 - 142, http://dx.doi.org/10.1111/ajco.12457
    Conference Papers | 2015
    Ashley DM; Gupta S; Truyen T; Wei L; Lorgelly PK; Thomas DM; Fox SB; Venkatesh S, 2015, 'Machine-learning prediction of cancer survival: A prospective study examining the impact of combining clinical and genomic data', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Clinical Science Symposium on Predicting and Improving Adverse Outcomes in Older Adults with Cancer, IL, Chicago, 29 May 2015 - 02 June 2015, http://dx.doi.org/10.1200/jco.2015.33.15_suppl.6521
    Conference Papers | 2015
    Cassier PA; Maki RG; Wagner AJ; Bompas E; Gelderblom H; Kroep JR; Thomas DM; Italiano A; Seddon BM; Van der Graaf WTA; Domont J; Blay J-Y; Stacchiotti S, 2015, 'Imatinib mesylate (IM) activity in patients (pts) with locally advanced tenosynovial giant cell tumor/pigmented villonodular synovitis (TGCT).', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Clinical Science Symposium on Predicting and Improving Adverse Outcomes in Older Adults with Cancer, IL, Chicago, 29 May 2015 - 02 June 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000358036900201&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Chantrill L; Nagrial A; Watson C; Johns A; Martyn-Smith M; Simpson S; Mead S; Jones M; Samra J; Gill A; Watson N; Chin V; Humphris J; Chou A; Brown B; Morey A; Thomas D; Sebastian L; Sjoquist K; Yip S; Pavlakis N; Asghari R; Harvey S; Grimison P; Simes J; Biankin A, 2015, 'Precision medicine for advanced pancreas cancer: the individualised molecular pancreatic cancer therapy (IMPACT) trial', in Asia-Pacific Journal of Clinical Oncology, WILEY-BLACKWELL, Vol. 11, pp. 147 - 148, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000364320800239&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Abstracts | 2015
    McBride KA; Young M-A; Schlub TE; Kirk J; Tattersall MHN; Ballinger M; Thomas D; Mitchell G, 2015, 'THE PSYCHOSOCIAL EFFECTS OF A WHOLE BODY MRI SCREENING TRIAL IN SARCOMA PATIENTS WITH A GERMLINE TP53 MUTATION', in Asia-Pacific Journal of Clinical Oncology, WILEY-BLACKWELL, Vol. 11, pp. 178 - 178, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000364320800325&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Peng G; Bojadzieva J; Ballinger ML; Thomas DM; Strong L; Wang W, 2015, 'LFSpro: A risk assessment tool to estimate TP53 mutation status in families with Li-Fraumeni syndrome', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, Vol. 75, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-2762
    Conference Abstracts | 2015
    Thomas D, 2015, 'RANKL and giant cell tumor of bone: the growing problem of benign tumours', in CLINICAL ENDOCRINOLOGY, WILEY, AUSTRALIA, Adelaide, Vol. 84, pp. 3 - 4, presented at Annual Scientific Meeting of the Endocrine-Society-of-Australia, AUSTRALIA, Adelaide, 23 August 2015 - 26 August 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000372310400010&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Thomas DM, 2015, 'MANAGING SARCOMA FROM A MEDICAL ONCOLOGIST PERSPECTIVE', in Asia-Pacific Journal of Clinical Oncology, WILEY-BLACKWELL, Vol. 11, pp. 75 - 75, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000364320800041&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Proceedings (Editor of) | 2014
    2014, 'WHAT DRIVES THE COST OF CANCER TREATMENT? INSIGHTS FROM AN ANALYSIS OF A LONGITUDINAL COHORT (CANCER 2015) LINKED TO ADMINISTRATIVE REIMBURSEMENT DATA', WILEY-BLACKWELL, Vol. 10, pp. 105 - 106, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000346343700315&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Presentations | 2014
    Lorgelly P; Doble B; Lucas M; Parisot J; Fox S; Thomas D, 2014, 'WHAT DRIVES THE COST OF CANCER TREATMENT? INSIGHTS FROM AN ANALYSIS OF A LONGITUDINAL COHORT (CANCER 2015) LINKED TO ADMINISTRATIVE REIMBURSEMENT DATA', Vol. 10, pp. 96 - 96, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000345350900067&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2014
    McBride KA; Schlub T; Thomas D; Tattersall M, 2014, 'AN INTERNATIONAL SURVEY OF AWARENESS OF GENETIC RISK IN THE CLINICAL SARCOMA COMMUNITY', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 22 - 22, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344745100050&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Posters | 2014
    McBride KA; Young M-A; Schlub TE; Ballinger ML; Kirk J; Tattersall MH; Thomas DM; Mitchell G, 2014, 'THE PSYCHOLOGICAL IMPACT OF A PILOT WHOLE-BODY SCREENING TRIAL (SMOC) ON INDIVIDUALS WITH LI-FRAUMENI SYNDROME', Vol. 10, pp. 166 - 167, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000345350900277&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2014
    Skubitz KM; Thomas DM; Chawla SP; Staddon AP; Engellau J; Feng A; Bach BA, 2014, 'Response to treatment with denosumab in patients with giant cell tumor of bone (GCTB): FDG PET results from two phase 2 trials.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, presented at 50th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 30 May 2014 - 03 June 2014, http://dx.doi.org/10.1200/jco.2014.32.15_suppl.10505
    Conference Presentations | 2014
    Thomas D, 2014, 'PULMONARY OLIGOMETASTATIC SARCOMA', Vol. 10, pp. 78 - 78, http://dx.doi.org/10.1111/ajco.12307
    Conference Posters | 2014
    Thomas D; Hicks RJ; Skubitz K; Chawla S; Staddon A; Engellau J; Feng A; Bach BA, 2014, 'RAPID FLUORODEOXYGLUCOSE-POSITRON EMISSION TOMOGRAPHY (FDG-PET) RESPONSE TO DENOSUMAB TREATMENT IN PATIENTS WITH GIANT CELL TUMOUR OF BONE (GCTB): RESULTS FROM TWO PHASE 2 TRIALS', Vol. 10, pp. 190 - 190, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000345350900341&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Doble B; Harris A; Thomas DM; Fox S; Lorgelly P, 2013, 'ASSESSING THE VALUE OF PRECISION THERAPIES IN THE MULTI-OMICS ERA OF MEDICINE', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 122 - 122, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000325868800196&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    James P; Thomas D, 2013, 'CANCER 2015-GENOME DEFINED CANCER RISK', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 64 - 64, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000325868800014&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Lewin J; Khamly K; Mitchell C; Hicks RJ; Toner GC; Ngan S; Powell G; Desai J; Choong P; Stacker S; Slavin J; Thomas DM, 2013, 'Hypoxia, angiogenic markers, and response to neoadjuvant radiotherapy in soft-tissue sarcomas', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, presented at 49th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2013 - 04 June 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000335419600343&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    McBride K; Kirk J; Mitchell G; Thomas D; Tattersall M; Young M-A, 2013, 'RESEARCH PARTICIPANTS' VIEWS OF THE FEEDBACK OF GENETIC TEST INFORMATION FOLLOWING PARTICIPATION IN THE INTERNATIONAL SARCOMA KINDRED STUDY (ISKS)', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 132 - 133, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000325868800229&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Parisot J; Thomas D; James P; Fox S; Fellowes A; Lorgelly P; Sullivan R, 2013, 'CANCER 2015-CROSS-DISCIPLINARY RESEARCH OF A GENOMIC CANCER COHORT', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 64 - 64, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000325868800013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Savage SA; Mirabelio L; Wang Z; Gastier-Foster J; Gorlick R; Khanna C; Flanagan AM; Tirabosco R; Andrulis IL; Wunder J; Gokgoz N; Patino-Garcia A; Sierrasesumaga L; Lecanda F; Kurucu N; Ilhan IE; Sari N; Serra M; Hattinger C; Picci P; Spector L; Barkauskas DA; Marina N; de Toledo SC; Petrilli S; Amary MF; Halai D; Thomas D; Douglass C; Meltzer P; Jacobs K; Chung CC; Berndt SI; Purdue MP; Caporaso NE; Tucker M; Rothman N; Landi MT; Silverman DT; Kraft P; Hunter DJ; Malats N; Kogevinas M; Wacholder S; Troisi R; Helman L; Fraumeni JF; Yeager M; Hoover R; Chanock SJ, 2013, 'Genome-wide association study identifies novel loci associated with osteosarcoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-4593
    Conference Papers | 2012
    Kerr LT; Young S; Williams ED; Thomas D; Johns TG, 2012, 'Discovery of new therapeutic strategies for rare cancers with defined genetic lesions', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM2012-3711
    Conference Papers | 2009
    Thomas DM; Chawla S; Skubitz K; Staddon A; Henshaw R; Blay J; Smith J; Ye Z; Roudier M; Jun S, 2009, 'Denosumab for the treatment of giant cell tumor (GCT) of bone: Final results from a proof-of-concept, phase II study', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, FL, Orlando, presented at 45th Annual Meeting of the American-Society-of-Clinical-Oncology, FL, Orlando, 29 May 2009 - 02 June 2009, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000276606606573&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2008
    Davis H; Vetere F; Ashkanasy S; Dyson G; Schofield P; Thompson K; Withers G; Thomas D, 2008, 'Towards social connection for young people with cancer', in Proceedings of the 20th Australasian Conference on Computer-Human Interaction: Designing for Habitus and Habitat, OZCHI'08, pp. 319 - 322, http://dx.doi.org/10.1145/1517744.1517804
    Conference Papers | 2006
    Thomas D; Clement J; Reeve J; Loveridge N, 2006, 'Remodelling clusters reduce local bone strain and favour canal merging', in JOURNAL OF BONE AND MINERAL RESEARCH, AMER SOC BONE & MINERAL RES, ENGLAND, Southampton, pp. 1152 - 1152, presented at Annual Meeting of the Bone-Research-Society, ENGLAND, Southampton, 05 July 2006 - 06 July 2006, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000238600900041&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2005
    Kuhn DM; Francescutti-Verbeem DM; Thomas DM, 2005, 'Dopamine quinones activate microglia and induce a neurotoxic gene expression profile - Relationship to methamphetamine-induced nerve ending damage', in Ali SF; Fornai F (ed.), CELLULAR AND MOLECULAR MECHANISMS OF DRUGS OF ABUSE AND NEUROTOXICITY: COCAINE, GHB, AND SUBSTITUTED AMPHETAMINES, BLACKWELL PUBLISHING, ITALY, Venice Int Univ, Venice, pp. 31 - 41, presented at Satellite Meeting on Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity - Cocaine, GHB and Substituted Amphetamines, ITALY, Venice Int Univ, Venice, 16 August 2005 - 19 August 2005, http://dx.doi.org/10.1196/annals.1369.003
    Conference Papers | 2004
    Mayhew P; Thomas D; Clement J; Loveridge N; Bonfield W; Beck T; Reeve J, 2004, 'Walking tall is poor long-term protection against hip fracture.', in JOURNAL OF BONE AND MINERAL RESEARCH, AMER SOC BONE & MINERAL RES, WA, Seattle, pp. S206 - S206, presented at 26th Annual Meeting of the American-Society-for-Bone-and-Mineral-Research, WA, Seattle, 01 October 2004 - 05 October 2004, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000224326801172&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2002
    Reeve J; Power J; Mayhew P; Thomas D; Kaptoge S; Loveridge N, 2002, 'Disease and ageing effects on bone renewal: influences on the mechanical properties of the skeleton', in BONE, ELSEVIER SCIENCE INC, GERMANY, MUNICH, pp. S22 - S22, presented at 2nd Annual Meeting of the International-Association-of-Forensic-Mental-Health-Services, GERMANY, MUNICH, 22 March 2002, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000186772400064&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2000
    Bell KL; Loveridge N; Reeve J; Thomas D; Feik S; Clement J, 2000, 'Cortical remodelling clusters (super-osteons) in the human femoral shaft.', in JOURNAL OF BONE AND MINERAL RESEARCH, AMER SOC BONE & MINERAL RES, pp. S237 - S237, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000088898400397&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

1998-2002: Neil Hamilton Fairley National Health and Medical Research Council Fellowship

2000: John Taplin Fellow, Harvard Medical School.

2002: Arnott Fellowship, Royal Australasian College of Physicians.

2003-2007: RD Wright NHMRC Career Development Award

2003-2004: Puzey fellowship, University of Melbourne

2006-2010: Edna and Murray Dunn Award

2007-2010: Victorian Cancer Agency, Clinician Researcher Fellowship

2008: Sam Sciacca Visiting Fellow, Queensland Cancer Council

2009: NHMRC Ten of the Best. Fellowship elected as one of the 10 best NHMRC investments for 2009

2011: Victorian Cancer Agency, Clinician Researcher Fellowship

2012-2015: NH&MRC Senior Research Fellow Level B

2014: Raine Visiting Professorship, University of Western Australia

2016-22: NH&MRC Principal Research Fellow

2018:David Danks Lecturer, Murdoch Children’s Medical Research Institute

         Kidson Lecturer, Queensland Institute of Medical Research

         President, Connective Tissue Oncology Society

         Named honor: Desai Thomas Award for Excellence in Sarcoma Research (inaugurated 2018)

2020: Herman Suit lecturer, CTOS.

2021:PWC Pearls Series: Emerging leaders in Sydney’s business community

As a clinician-scientist, I apply genomic technologies to the understanding and management of cancer. I founded the Australasian Sarcoma Study Group, which has enrolled over 1,000 patients onto research studies since 2008, and provided over $1.1M of funding through 18 grants to young researchers. I founded and lead the International Sarcoma Kindred Study, the largest ever conducted study of genetic factors in sarcoma, now recruiting from 23 centres in the US, UK, France, India, South Korea, New Zealand and Australia. I led the first international study of denosumab in Giant Cell Tumor of bone, leading to FDA, EMA and TGA approval of this agent for the management of this disorder. I also co-led a meta-analysis of whole body MRI screening for patients with Li-Fraumeni syndrome, changing clinical practice guidelines from the NCCN, AACR and EviQ in Australia. I am the CEO of Omico, a Federally-funded national precision oncology platform which focuses on using genomics to develop biomarker-dependent clinical trials infrastructure, and genetically stratified risk management. Omico has enabled more than 5,000 Australians with advanced cancer to access genomic profiling, and matched targeted therapies. He has over 230 research publications, including first or last author papers in Science, Cancer Cell, Molecular Cell, JAMA Oncology, Lancet Oncology, Journal of Clinical Oncology, Cancer Discovery, Journal of Clinical Investigation and Nature Communications. My work has been cited more than 10,000 times, with an H-index of 52 (September 2022, Web of Science).

My Research Supervision

Dr Min Li Huang (PhD)

Dr Aaron Wong (PhD)

Dr Milita Zaheed (PhD)

Ms Kelsy Prest (PhD)