Dr Jelena   Rnjak-Kovacina
Senior Lecturer

Dr Jelena Rnjak-Kovacina

Education & Training

Postdoctoral scholar- Department of Biomedical Engineering, Tufts University, Boston, USA, 2011-2013

Research area: Development of novel silk-based biomaterials for tissue engineering and regenerative medicine, Supervisor: Prof David Kaplan

Doctor of Philosophy, School of Molecular Bioscience, University of Sydney, 2011

Research area: Development of human elastin-based dermal substitutes for the treatment of severe burn injuries, Supervisor: Prof Antony Weiss

Bachelor of Science (Molecular Biology & Genetics) (Honours I) (University Medal),University of Sydney, 2007

Engineering
Grad Sch: Biomedical Eng

Dr Jelena Rnjak-Kovacina is a Senior Lecturer and Heart Foundation Future Leader Fellow at the Graduate School of Biomedical Engineering. She completed her doctoral degree in Prof Anthony Weiss' lab at the University of Sydney and postdoctoral training in Prof David Kaplan’s group at Tufts University in Boston prior to joining UNSW in 2014. Her research interests are at the interface of biology and engineering, focusing on the development of novel, biomimetic biomaterial platforms with tuneable physical and biological features that direct cellular behaviour and function. She develops biomaterial platforms to study the effects of physical and biological cues on the vascularisation of bioengineered tissues and the biological mechanisms underpinning this process, as well novel functional cardiovascular implant devices, including vascular grafts and cardiac patches.

 


 


 

Location
Samuels Building F25 Level 5, Room 507 UNSW Sydney NSW 2052 AUSTRALIA

Publications

  • Book Chapters | 2017
    Dr Jelena Rnjak-Kovacina
    Rnjak-Kovacina J; Daamen WF; Orbanić D; Rodríguez-Cabello JC; Weiss AS, 2017, 'Elastin Biopolymers', in Comprehensive Biomaterials II, pp. 412 - 437, http://dx.doi.org/10.1016/b978-0-12-803581-8.10187-0
    Book Chapters | 2017
    Dr Jelena Rnjak-Kovacina
    Rnjak-Kovacina J; Daamen WF; Orbanić D; Rodríguez-Cabello JC; Weiss AS, 2017, '2.18 Elastin biopolymers', in Comprehensive Biomaterials II, pp. 412 - 437, http://dx.doi.org/10.1016/B978-0-12-803581-8.10187-0
    Book Chapters | 2013
    Dr Jelena Rnjak-Kovacina
    Rnjak-Kovacina J; Weiss AS, 2013, 'The Role of Elastin in Wound Healing and Dermal Substitute Design', in Kamolz L-P; Lumenta DB (ed.), Dermal Replacements in General, Burn, and Plastic Surgery, Springer Science & Business, pp. 57 - 66, http://dx.doi.org/10.1007/978-3-7091-1586-2_5
    Book Chapters | 2011
    Dr Jelena Rnjak-Kovacina
    Rnjak-Kovacina J; Daamen WF; Pierna M; Rodríguez-Cabello JC; Weiss AS, 2011, 'Elastin Biopolymers', in Comprehensive Biomaterials, Elsevier, pp. 329 - 346, http://dx.doi.org/10.1016/b978-0-08-055294-1.00071-4
    Book Chapters | 2011
    Dr Jelena Rnjak-Kovacina
    Rnjak-Kovacina J; Daamen, WF ; Pierna, M ; Rodriguez-Cabello, JC ; Weiss, AS , 2011, 'Elastin Biopolymers', in Ducheyne P; Healy K; Hutmacher DE; Grainger DW; Kirkpatrick CJ (ed.), Comprehensive Biomaterials, Elsevier
  • Journal articles | 2021
    Dr Jelena Rnjak-Kovacina
    Monfared M; Mawad D; Rnjak-Kovacina J; Stenzel MH, 2021, '3D bioprinting of dual-crosslinked nanocellulose hydrogels for tissue engineering applications', JOURNAL OF MATERIALS CHEMISTRY B, http://dx.doi.org/10.1039/d1tb00624j
    Journal articles | 2021
    Dr Jelena Rnjak-Kovacina
    Chandrasekar K; Farrugia BL; Johnson L; Marks D; Irving D; Elgundi Z; Lau K; Kim HN; Rnjak-Kovacina J; Bilek MM; Whitelock JM; Lord MS, 2021, 'Effect of Recombinant Human Perlecan Domain V Tethering Method on Protein Orientation and Blood Contacting Activity on Polyvinyl Chloride', Advanced Healthcare Materials, http://dx.doi.org/10.1002/adhm.202100388
    Journal articles | 2021
    Dr Jelena Rnjak-Kovacina
    Joukhdar H; Seifert A; Jüngst T; Groll J; Lord MS; Rnjak-Kovacina J, 2021, 'Ice Templating Soft Matter: Fundamental Principles and Fabrication Approaches to Tailor Pore Structure and Morphology and Their Biomedical Applications', Advanced Materials, http://dx.doi.org/10.1002/adma.202100091
    Journal articles | 2021
    Dr Jelena Rnjak-Kovacina
    Polonchuk L; Surija L; Lee MH; Sharma P; Liu Chung Ming C; Richter F; Ben-Sefer E; Alsadat Rad M; Mahmodi Sheikh Sarmast H; Al Shamery W; Tran HA; Vettori L; Haeusermann F; Filipe EC; Rnjak-Kovacina J; Cox T; Tipper J; Kabakova I; Gentile C, 2021, 'Towards engineering heart tissues from bioprinted cardiac spheroids.', Biofabrication, http://dx.doi.org/10.1088/1758-5090/ac14ca
    Journal articles | 2021
    Dr Jelena Rnjak-Kovacina
    Yang N; Moore MJ; Michael PL; Santos M; Lam YT; Bao S; Ng MKC; Rnjak-Kovacina J; Tan RP; Wise SG, 2021, 'Silk Fibroin Scaffold Architecture Regulates Inflammatory Responses and Engraftment of Bone Marrow-Mononuclear Cells', Advanced Healthcare Materials, http://dx.doi.org/10.1002/adhm.202100615
    Journal articles | 2021
    Dr Jelena Rnjak-Kovacina
    Longoni A; Li J; Lindberg GCJ; Rnjak-Kovacina J; Wise LM; Hooper GJ; Woodfield TBF; Kieser DC; Lim KS, 2021, 'Strategies for inclusion of growth factors into 3D printed bone grafts.', Essays Biochem, http://dx.doi.org/10.1042/EBC20200130
    Journal articles | 2021
    Dr Jelena Rnjak-Kovacina
    Yan Y; Travaglini L; Lau K; Rnjak-Kovacina J; Ta D; Eslami M; Yang S; Lauto A; Officer DL; Mawad D, 2021, 'Impact of Sterilization on a Conjugated Polymer-Based Bioelectronic Patch', ACS Applied Polymer Materials, vol. 3, pp. 2541 - 2552, http://dx.doi.org/10.1021/acsapm.1c00131
    Journal articles | 2021
    Dr Jelena Rnjak-Kovacina
    Lau K; Waterhouse A; Akhavan B; Gao L; Kim HN; Tang F; Whitelock JM; Bilek MM; Lord MS; Rnjak-Kovacina J, 2021, 'Biomimetic silk biomaterials: Perlecan-functionalized silk fibroin for use in blood-contacting devices', Acta Biomaterialia, http://dx.doi.org/10.1016/j.actbio.2021.02.014
    Journal articles | 2020
    Dr Jelena Rnjak-Kovacina
    Cui X; Soliman BG; Alcala-Orozco CR; Li J; Vis MAM; Santos M; Wise SG; Levato R; Malda J; Woodfield TBF; Rnjak-Kovacina J; Lim KS, 2020, 'Rapid Photocrosslinking of Silk Hydrogels with High Cell Density and Enhanced Shape Fidelity', Advanced Healthcare Materials, vol. 9, pp. e1901667, http://dx.doi.org/10.1002/adhm.201901667
    Journal articles | 2020
    Dr Jelena Rnjak-Kovacina
    Lau K; Akhavan B; Lord MS; Bilek MM; Rnjak-Kovacina J, 2020, 'Dry Surface Treatments of Silk Biomaterials and Their Utility in Biomedical Applications', ACS Biomaterials Science and Engineering, vol. 6, pp. 5431 - 5452, http://dx.doi.org/10.1021/acsbiomaterials.0c00888
    Journal articles | 2020
    Dr Jelena Rnjak-Kovacina
    Tang F; Manz XD; Bongers A; Odell RA; Joukhdar H; Whitelock JM; Lord MS; Rnjak-Kovacina J, 2020, 'Microchannels are an architectural cue that promotes integration and vascularization of silk biomaterials in vivo', ACS Biomaterials Science and Engineering, vol. 6, pp. 1476 - 1486, http://dx.doi.org/10.1021/acsbiomaterials.9b01624
    Journal articles | 2020
    Dr Jelena Rnjak-Kovacina
    Eslami M; Zeglio E; Alosaimi G; Yan Y; Ruprai H; Macmillan A; Seidel J; Lauto A; Joukhdar H; Rnjak-Kovacina J; Mawad D, 2020, 'A One Step Procedure toward Conductive Suspensions of Liposome-Polyaniline Complexes', Macromolecular Bioscience, vol. 20, http://dx.doi.org/10.1002/mabi.202000103
    Journal articles | 2020
    Dr Jelena Rnjak-Kovacina
    Baptista M; Joukhdar H; Alcala-Orozco CR; Lau K; Jiang S; Cui X; He S; Tang F; Heu C; Woodfield TBF; Lim KS; Rnjak-Kovacina J, 2020, 'Silk fibroin photo-lyogels containing microchannels as a biomaterial platform for: In situ tissue engineering', Biomaterials Science, vol. 8, pp. 7093 - 7105, http://dx.doi.org/10.1039/d0bm01010c
    Journal articles | 2020
    Dr Jelena Rnjak-Kovacina
    Cui X; Soliman BG; Alcala-Orozco CR; Li J; Vis MAM; Santos M; Wise SG; Levato R; Malda J; Woodfield TBF; Rnjak-Kovacina J; Lim KS, 2020, 'Correction to: Rapid Photocrosslinking of Silk Hydrogels with High Cell Density and Enhanced Shape Fidelity (Adv. Healthcare Mater, (2020), 9, (1901667), 10.1002/adhm.201901667)', Advanced Healthcare Materials, vol. 9, http://dx.doi.org/10.1002/adhm.202001801
    Journal articles | 2020
    Dr Jelena Rnjak-Kovacina
    Lin X; Tang F; Jiang S; Khamis H; Bongers A; Whitelock JM; Lord MS; Rnjak-Kovacina J, 2020, 'A Biomimetic Approach toward Enhancing Angiogenesis: Recombinantly Expressed Domain V of Human Perlecan Is a Bioactive Molecule That Promotes Angiogenesis and Vascularization of Implanted Biomaterials', Adv. Sci., vol. 7, pp. 2000900, http://dx.doi.org/10.1002/advs.202000900
    Journal articles | 2020
    Dr Jelena Rnjak-Kovacina
    Atienza-Roca P; Kieser DC; Cui X; Bathish B; Ramaswamy Y; Hooper GJ; Clarkson AN; Rnjak-Kovacina J; Martens PJ; Wise LM; Woodfield TBF; Lim KS, 2020, 'Visible light mediated PVA-tyramine hydrogels for covalent incorporation and tailorable release of functional growth factors', Biomaterials Science, vol. 8, pp. 5005 - 5019, http://dx.doi.org/10.1039/d0bm00603c
    Journal articles | 2020
    Dr Jelena Rnjak-Kovacina
    Vettori L; Sharma P; Rnjak-Kovacina J; Gentile C, 2020, '3D Bioprinting of Cardiovascular Tissues for In Vivo and In Vitro Applications Using Hybrid Hydrogels Containing Silk Fibroin: State of the Art and Challenges', Current Tissue Microenvironment Reports, vol. 1, pp. 261 - 276, http://dx.doi.org/10.1007/s43152-020-00026-5
    Journal articles | 2019
    Dr Jelena Rnjak-Kovacina
    Holland C; Numata K; Rnjak-Kovacina J; Seib FP, 2019, 'The Biomedical Use of Silk: Past, Present, Future', Advanced Healthcare Materials, vol. 8, http://dx.doi.org/10.1002/adhm.201800465
    Journal articles | 2019
    Dr Jelena Rnjak-Kovacina
    Lim KS; Baptista M; Moon S; Woodfield TBF; Rnjak-Kovacina J, 2019, 'Microchannels in Development, Survival, and Vascularisation of Tissue Analogues for Regenerative Medicine', Trends in Biotechnology, vol. 37, pp. 1189 - 1201, http://dx.doi.org/10.1016/j.tibtech.2019.04.004
    Journal articles | 2019
    Dr Jelena Rnjak-Kovacina
    Rnjak-Kovacina J; Gerrand YW; Wray LS; Tan B; Joukhdar H; Kaplan DL; Morrison WA; Mitchell GM, 2019, 'Vascular Pedicle and Microchannels: Simple Methods Toward Effective In Vivo Vascularization of 3D Scaffolds', Advanced Healthcare Materials, vol. 8, http://dx.doi.org/10.1002/adhm.201901106
    Journal articles | 2019
    Dr Jelena Rnjak-Kovacina
    Chan AHP; Filipe EC; Tan RP; Santos M; Yang N; Hung J; Feng J; Nazir S; Benn AJ; Ng MKC; Rnjak-Kovacina J; Wise SG, 2019, 'Altered processing enhances the efficacy of small-diameter silk fibroin vascular grafts', Scientific Reports, vol. 9, http://dx.doi.org/10.1038/s41598-019-53972-y
    Journal articles | 2018
    Dr Jelena Rnjak-Kovacina
    Filipe EC; Santos M; Hung J; Lee BSL; Yang N; Chan AHP; Ng MKC; Rnjak-Kovacina J; Wise SG, 2018, 'Rapid Endothelialization of Off-the-Shelf Small Diameter Silk Vascular Grafts', JACC: Basic to Translational Science, vol. 3, pp. 38 - 53, http://dx.doi.org/10.1016/j.jacbts.2017.12.003
    Journal articles | 2018
    Dr Jelena Rnjak-Kovacina
    Lord M; Rnjak-Kovacina J; Tang F; Whitelock J, 2018, 'Glycosaminoglycan and Proteoglycan-Based Biomaterials: Current Trends and Future Perspectives', Advanced Healthcare Materials, vol. 7, pp. 1701042 - 1701042, http://dx.doi.org/10.1002/adhm.201701042
    Journal articles | 2018
    Dr Jelena Rnjak-Kovacina
    Kondyurin A; Lau K; Tang F; Akhavan B; Chrzanowski W; Lord MS; Rnjak-Kovacina J; Bilek MM, 2018, 'Plasma Ion Implantation of Silk Biomaterials Enabling Direct Covalent Immobilization of Bioactive Agents for Enhanced Cellular Responses', ACS Applied Materials and Interfaces, vol. 10, pp. 17605 - 17616, http://dx.doi.org/10.1021/acsami.8b03182
    Journal articles | 2018
    Dr Jelena Rnjak-Kovacina
    Lord MS; Tang F; Rnjak-Kovacina J; Smith JGW; Melrose J; Whitelock JM, 2018, 'The multifaceted roles of perlecan in fibrosis', Matrix Biology, vol. 68-69, pp. 150 - 166, http://dx.doi.org/10.1016/j.matbio.2018.02.013
    Journal articles | 2018
    Dr Jelena Rnjak-Kovacina
    Tan RP; Chan AHP; Lennartsson K; Miravet MM; Lee BSL; Rnjak-Kovacina J; Clayton ZE; Cooke JP; Ng MKC; Patel S; Wise SG, 2018, 'Integration of induced pluripotent stem cell-derived endothelial cells with polycaprolactone/gelatin-based electrospun scaffolds for enhanced therapeutic angiogenesis', Stem Cell Research and Therapy, vol. 9, http://dx.doi.org/10.1186/s13287-018-0824-2
    Journal articles | 2017
    Dr Jelena Rnjak-Kovacina
    Rnjak-Kovacina J; Tang F; Lin X; Whitelock JM; Lord MS, 2017, 'Recombinant Domain V of Human Perlecan Is a Bioactive Vascular Proteoglycan', Biotechnology Journal, vol. 12, http://dx.doi.org/10.1002/biot.201700196
    Journal articles | 2016
    Dr Jelena Rnjak-Kovacina
    Ghezzi CE; Wang L; Behlau I; Rnjak-Kovacina J; Wang S; Goldstein MH; Liu J; Marchant JK; Rosenblatt MI; Kaplan DL, 2016, 'Degradation of silk films in multipocket corneal stromal rabbit models', Journal of Applied Biomaterials and Functional Materials, vol. 14, pp. e266 - e276, http://dx.doi.org/10.5301/jabfm.5000274
    Journal articles | 2016
    Dr Jelena Rnjak-Kovacina
    Roberts JJ; Farrugia BL; Green RA; Rnjak-Kovacina J; Martens PJ, 2016, 'In situ formation of poly(vinyl alcohol)–heparin hydrogels for mild encapsulation and prolonged release of basic fibroblast growth factor and vascular endothelial growth factor', Journal of Tissue Engineering, vol. 7, pp. 2041731416677132, http://dx.doi.org/10.1177/2041731416677132
    Journal articles | 2016
    Dr Jelena Rnjak-Kovacina
    Rnjak-Kovacina J; Tang F; Whitelock JM; Lord MS, 2016, 'Silk biomaterials functionalized with recombinant domain V of human perlecan modulate endothelial cell and platelet interactions for vascular applications', Colloids and Surfaces B: Biointerfaces, vol. 148, pp. 130 - 138, http://dx.doi.org/10.1016/j.colsurfb.2016.08.039
    Journal articles | 2016
    Dr Jelena Rnjak-Kovacina
    Lord MS; Cheng B; Tang F; Lyons JG; Rnjak-Kovacina J; Whitelock JM, 2016, 'Bioengineered human heparin with anticoagulant activity', Metabolic Engineering, vol. 38, pp. 105 - 114, http://dx.doi.org/10.1016/j.ymben.2016.07.006
    Journal articles | 2016
    Dr Jelena Rnjak-Kovacina
    Lord M; Chuang C; Rnjak‐Kovacina J; Cheng B; Lyons G; Whitelock J, 2016, 'Bioengineering Proteoglycan‐based Matrices For Blood Contacting Applications', The FASEB Journal, vol. 30, http://dx.doi.org/10.1096/fasebj.30.1_supplement.622.2
    Journal articles | 2016
    Dr Jelena Rnjak-Kovacina
    Filipe E; Santos M; Hung J; Rnjak-Kovacina J; Ng M; Wise S, 2016, 'Bioengineering Synthetic Silk Conduits for Arterial Revascularisation', Heart, Lung and Circulation, vol. 25, pp. S32 - S32, http://dx.doi.org/10.1016/j.hlc.2016.06.072
    Journal articles | 2015
    Dr Jelena Rnjak-Kovacina
    Ghezzi CE; Rnjak-Kovacina J; Kaplan DL, 2015, 'Corneal Tissue Engineering: Recent Advances and Future Perspectives', Tissue Engineering - Part B: Reviews, vol. 21, pp. 278 - 287, http://dx.doi.org/10.1089/ten.teb.2014.0397
    Journal articles | 2015
    Dr Jelena Rnjak-Kovacina
    Rnjak-Kovacina J; Wray LS; Burke KA; Torregrosa T; Golinski JM; Huang W; Kaplan DL, 2015, 'Lyophilized Silk Sponges: A Versatile Biomaterial Platform for Soft Tissue Engineering', ACS Biomaterials Science and Engineering, vol. 1, pp. 260 - 270, http://dx.doi.org/10.1021/ab500149p
    Journal articles | 2015
    Dr Jelena Rnjak-Kovacina
    Zhang W; Wray LS; Rnjak-Kovacina J; Xu L; Zou D; Wang S; Zhang M; Dong J; Li G; Kaplan DL; Jiang X, 2015, 'Vascularization of hollow channel-modified porous silk scaffolds with endothelial cells for tissue regeneration', Biomaterials, vol. 56, pp. 68 - 77, http://dx.doi.org/10.1016/j.biomaterials.2015.03.053
    Journal articles | 2015
    Dr Jelena Rnjak-Kovacina
    Rnjak-Kovacina J; Desrochers TM; Burke KA; Kaplan DL, 2015, 'The effect of sterilization on silk fibroin biomaterial properties', Macromolecular Bioscience, vol. 15, pp. 861 - 874, http://dx.doi.org/10.1002/mabi.201500013
    Journal articles | 2015
    Dr Jelena Rnjak-Kovacina
    Chen Y; Lin Y; Davis KM; Wang Q; Rnjak-Kovacina J; Li C; Isberg RR; Kumamoto CA; Mecsas J; Kaplan DL, 2015, 'Robust bioengineered 3D functional human intestinal epithelium', Scientific Reports, vol. 5, http://dx.doi.org/10.1038/srep13708
    Journal articles | 2015
    Dr Jelena Rnjak-Kovacina
    Lord MS; Farrugia BL; Rnjak-Kovacina J; Whitelock JM, 2015, 'Current serological possibilities for the diagnosis of arthritis with special focus on proteins and proteoglycans from the extracellular matrix', Expert Review of Molecular Diagnostics, vol. 15, pp. 77 - 95, http://dx.doi.org/10.1586/14737159.2015.979158
    Journal articles | 2014
    Dr Jelena Rnjak-Kovacina
    Partlow BP; Hanna CW; Rnjak-Kovacina J; Moreau JE; Applegate MB; Burke KA; Marelli B; Mitropoulos AN; Omenetto FG; Kaplan DL, 2014, 'Highly tunable elastomeric silk biomaterials', Advanced Functional Materials, vol. 24, pp. 4615 - 4624, http://dx.doi.org/10.1002/adfm.201400526
    Journal articles | 2014
    Dr Jelena Rnjak-Kovacina
    Wu J; Funderburgh JL; Rnjak-Kovacina J; Kaplan DL; Du Y; Funderburgh ML, 2014, 'Corneal stromal bioequivalents secreted on patterned silk substrates', Biomaterials, http://dx.doi.org/10.1016/j.biomaterials.2013.12.078
    Journal articles | 2014
    Dr Jelena Rnjak-Kovacina
    Rnjak-Kovacina J; Wray LS; Golinski JM; Kaplan DL, 2014, 'Arrayed hollow channels in silk-based scaffolds provide functional outcomes for engineering critically sized tissue constructs', Advanced Functional Materials, vol. 24, pp. 2188 - 2196, http://dx.doi.org/10.1002/adfm.201302901
    Journal articles | 2014
    Dr Jelena Rnjak-Kovacina
    Wise SG; Yeo GC; Hiob MA; Rnjak-Kovacina J; Kaplan DL; Ng MKC; Weiss AS, 2014, 'Tropoelastin: A versatile, bioactive assembly module', Acta Biomaterialia, vol. 10, pp. 1532 - 1541, http://dx.doi.org/10.1016/j.actbio.2013.08.003
    Journal articles | 2014
    Dr Jelena Rnjak-Kovacina
    Liu H; Bao S; Wise SG; Weiss AS; Rnjak-Kovacina J; Kaplan DL; Bilek MMM; Fei J, 2014, 'Biocompatibility of silk-tropoelastin protein polymers', Biomaterials, http://dx.doi.org/10.1016/j.biomaterials.2014.03.024
    Journal articles | 2014
    Dr Jelena Rnjak-Kovacina
    McNamara SL; Rnjak-Kovacina J; Lo TJ; Kaplan DL; Schmidt DF, 2014, 'Silk as a biocohesive sacrificial binder in the fabrication of hydroxyapatite load bearing scaffolds', Biomaterials, http://dx.doi.org/10.1016/j.biomaterials.2014.05.013
    Journal articles | 2014
    Dr Jelena Rnjak-Kovacina
    Wu J; Rnjak-Kovacina J; Du Y; Funderburgh ML; Kaplan DL; Funderburgh JL, 2014, 'Corneal stromal bioequivalents secreted on patterned silk substrates', Biomaterials, vol. 35, pp. 3744 - 3755, http://dx.doi.org/10.1016/j.biomaterials.2013.12.078
    Journal articles | 2014
    Dr Jelena Rnjak-Kovacina
    Liu H; Wise SG; Rnjak-Kovacina J; Kaplan DL; Bilek MMM; Weiss AS; Fei J; Bao S, 2014, 'Biocompatibility of silk-tropoelastin protein polymers', Biomaterials, vol. 35, pp. 5138 - 5147, http://dx.doi.org/10.1016/j.biomaterials.2014.03.024
    Journal articles | 2014
    Dr Jelena Rnjak-Kovacina
    McNamara SL; Rnjak-Kovacina J; Schmidt DF; Lo TJ; Kaplan DL, 2014, 'Silk as a biocohesive sacrificial binder in the fabrication of hydroxyapatite load bearing scaffolds', Biomaterials, vol. 35, pp. 6941 - 6953, http://dx.doi.org/10.1016/j.biomaterials.2014.05.013
    Journal articles | 2013
    Dr Jelena Rnjak-Kovacina
    Shang K; Rnjak-Kovacina J; Lin Y; Hayden RS; Tao H; Kaplan DL, 2013, 'Accelerated In Vitro Degradation of Optically Clear Low beta-Sheet Silk Films by Enzyme-Mediated Pretreatment', TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, vol. 2, http://dx.doi.org/10.1167/tvst.2.3.2
    Journal articles | 2013
    Dr Jelena Rnjak-Kovacina
    Reddel CJ; Cultrone D; Rnjak-Kovacina J; Weiss AS; Burgess JK, 2013, 'Tropoelastin modulates TGF-β1-induced expression of VEGF and CTGF in airway smooth muscle cells', Matrix Biology, vol. 32, pp. 407 - 413, http://dx.doi.org/10.1016/j.matbio.2013.04.003
    Journal articles | 2013
    Dr Jelena Rnjak-Kovacina
    Seib FP; Jones GT; Rnjak-Kovacina J; Lin Y; Kaplan DL, 2013, 'pH-Dependent Anticancer Drug Release from Silk Nanoparticles', Advanced Healthcare Materials, vol. 2, pp. 1606 - 1611, http://dx.doi.org/10.1002/adhm.201300034
    Journal articles | 2013
    Dr Jelena Rnjak-Kovacina
    Ghezzi CE; Rnjak-Kovacina J; Weiss AS; Kaplan DL, 2013, 'Multifunctional silk-tropoelastin biomaterial systems', Israel Journal of Chemistry, vol. 53, pp. 777 - 786, http://dx.doi.org/10.1002/ijch.201300082
    Journal articles | 2012
    Dr Jelena Rnjak-Kovacina
    Wray LS; Rnjak-Kovacina J; Mandal BB; Schmidt DF; Gil ES; Kaplan DL, 2012, 'A silk-based scaffold platform with tunable architecture for engineering critically-sized tissue constructs', Biomaterials, vol. 33, pp. 9214 - 9224, http://dx.doi.org/10.1016/j.biomaterials.2012.09.017
    Journal articles | 2012
    Dr Jelena Rnjak-Kovacina
    Rnjak-kovacina J; Wise SG; Li Z; Maitz PK; Young C; Wang Y; Weiss AS, 2012, 'Electrospun synthetic human elastin:collagen composite scaffolds for dermal tissue engineering', ACTA Biomaterialia, vol. 8, pp. 3714 - 3722, http://dx.doi.org/10.1016/j.actbio.2012.06.032
    Journal articles | 2011
    Dr Jelena Rnjak-Kovacina
    Rnjak J; Wise SG; Mithieux SM; Weiss AS, 2011, 'Severe burn injuries and the role of Elastin in the design of dermal substitutes', Tissue Engineering - Part B: Reviews, vol. 17, pp. 81 - 91, http://dx.doi.org/10.1089/ten.teb.2010.0452
    Journal articles | 2011
    Dr Jelena Rnjak-Kovacina
    Rnjak-Kovacina J; Weiss AS, 2011, 'Increasing the pore size of electrospun scaffolds', Tissue Engineering - Part B: Reviews, vol. 17, pp. 365 - 372, http://dx.doi.org/10.1089/ten.teb.2011.0235
    Journal articles | 2011
    Dr Jelena Rnjak-Kovacina
    Rnjak-kovacina J; Wise SG; Li Z; Maitz PK; Young C; Wang Y; Weiss A, 2011, 'Tailoring the porosity and pore size of electrospun synthetic human elastin scaffolds for dermal tissue engineering', Biomaterials, vol. 32, pp. 6729 - 6736, http://dx.doi.org/10.1016/j.biomaterials.2011.05.065
    Journal articles | 2011
    Dr Jelena Rnjak-Kovacina
    Rnjak J; Annabi N; Dehghani F; Weiss AS, 2011, 'Elastin-based dermal substitutes', 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials
    Journal articles | 2010
    Dr Jelena Rnjak-Kovacina
    Hu X; Wang X; Rnjak J; Weiss AS; Kaplan DL, 2010, 'Biomaterials derived from silk-tropoelastin protein systems', Biomaterials, vol. 31, pp. 8121 - 8131, http://dx.doi.org/10.1016/j.biomaterials.2010.07.044
    Journal articles | 2010
    Dr Jelena Rnjak-Kovacina
    Almine JF; Bax DV; Mithieux SM; Smith LN; Rnjak J; Waterhouse A; Wise SG; Weiss AS, 2010, 'Elastin-based materials', Chemical Society Reviews, vol. 39, pp. 3371 - 3379, http://dx.doi.org/10.1039/b919452p
    Journal articles | 2010
    Dr Jelena Rnjak-Kovacina
    Nivison-Smith L; Rnjak J; Weiss AS, 2010, 'Synthetic human elastin microfibers: Stable cross-linked tropoelastin and cell interactive constructs for tissue engineering applications', Acta Biomaterialia, vol. 6, pp. 354 - 359, http://dx.doi.org/10.1016/j.actbio.2009.08.011
    Journal articles | 2010
    Dr Jelena Rnjak-Kovacina
    Almine JF; Bax DV; Mithieux SM; Nivison-Smith L; Rnjak J; Waterhouse A; Wise SG; Weiss AS, 2010, 'ChemInform Abstract: Elastin-Based Materials', ChemInform, vol. 41, pp. no - no, http://dx.doi.org/10.1002/chin.201051252
    Journal articles | 2009
    Dr Jelena Rnjak-Kovacina
    Rnjak J; Li Z; Maitz PKM; Wise SG; Weiss AS, 2009, 'Primary human dermal fibroblast interactions with open weave three-dimensional scaffolds prepared from synthetic human elastin', Biomaterials, vol. 30, pp. 6469 - 6477, http://dx.doi.org/10.1016/j.biomaterials.2009.08.017
  • Conference Abstracts | 2016
    Dr Jelena Rnjak-Kovacina
    Filipe E; Santos M; Hung J; Tan RP; Chan AP; Michael PL; Ng MK; Rnjak-Kovacina J; Wise SG, 2016, 'Bioengineered Silk Conduits are Effective for Small Diameter Revascularisation', in Circulation, American Heart Association, presented at Circulation
    Conference Abstracts | 2016
    Dr Jelena Rnjak-Kovacina
    Tang F; Lau K; Kondyurin A; Lord MS; Whitelock JM; Bilek MM; Rnjak-Kovacina J, 2016, 'Plasma Immersion Ion Implantation Treatment of Silk Biomaterials Enhances Biological Function', in Plasma Immersion Ion Implantation Treatment of Silk Biomaterials Enhances Biological Function, TISSUE ENGINEERING PART A, San Diego, Vol. 22, pp. S129 - S129, presented at TISSUE ENGINEERING PART A, San Diego, 11 December 2016 - 14 December 2016
    Conference Abstracts | 2016
    Dr Jelena Rnjak-Kovacina
    Rnjak-Kovacina J; Tang F; Whitelock JM; Lord MS, 2016, 'Domain V of Perlecan Covalently Immobilized on Silk Biomaterials Modulates Endothelial Cell and Platelet Interactions for Vascular Applications', in TISSUE ENGINEERING PART A, MARY ANN LIEBERT, INC, San Diego, CA, Vol. 22, pp. S20 - S21, presented at TERMIS - Americas Conference and Exhibition, San Diego, CA, 11 December 2016 - 14 December 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000390569200074&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Dr Jelena Rnjak-Kovacina
    Lord M; chuang C; rnjak-kovacina J; cheng B; lyons G; whitelock J, 2016, 'Bioengineering proteoglycan-based matrices for blood contacting applications', in The FASEB Journal, Federation of American Society of Experimental Biology (FASEB), San Diego, Vol. 6, pp. 622.2 - 622.2, presented at Experimental Biology 2016, San Diego, 02 April 2016 - 06 April 2016
    Conference Papers | 2016
    Dr Jelena Rnjak-Kovacina
    Passipieri J; Stroppel WL; Mintz E; Baker HB; Rnjak-Kovacina J; Kaplan DL; Christ GJ, 2016, 'Further Development of Silk Biomaterials for a Tissue Engineered Muscle Repair (TEMR) Platform: Enhanced Cellular Coverage and Unidirectional Orientation of Muscle Progenitor Cells Following Bioreactor Pre-Conditioning', in Further Development of Silk Biomaterials for a Tissue Engineered Muscle Repair (TEMR) Platform: Enhanced Cellular Coverage and Unidirectional Orientation of Muscle Progenitor Cells Following Bioreacto, TISSUE ENGINEERING PART A, San Diego, pp. S87 - S87, presented at TISSUE ENGINEERING PART A, San Diego, 11 December 2016 - 14 December 2016
    Conference Abstracts | 2015
    Dr Jelena Rnjak-Kovacina
    Filipe EC; Santos M; Hung J; Tan RP; Chan AP; Michael PL; Ng MK; Rnjak-Kovacina J; Wise SG, 2015, 'Water Vapor Annealing of Silk for Vascular Grafts', in TISSUE ENGINEERING PART A, MARY ANN LIEBERT, INC, Boston, MA, Vol. 21, pp. S211 - S211, presented at 4th TERMIS World Congress, Boston, MA, 08 September 2015 - 11 September 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360205201426&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2015
    Dr Jelena Rnjak-Kovacina
    Knothe Tate ML; Pereira A; Kaplan D; Rnjak-Kovacina J, 2015, 'Computationally-Driven Design of Novel Drug Delivery Patches', in Computationally-Driven Design of Novel Drug Delivery Patches, Frontiers in Medical Devices Conference: Innovations in Modeling and Simulation - Using Modeling and Simulation at Different Stages in the Total Product Life Cycle, presented at Frontiers in Medical Devices Conference: Innovations in Modeling and Simulation - Using Modeling and Simulation at Different Stages in the Total Product Life Cycle, 18 May 2015 - 20 May 2015, http://bmes.org/meddevicesconference
    Conference Papers | 2015
    Dr Jelena Rnjak-Kovacina
    Rnjak-Kovacina J; Wray LS; Zhang W; Jiang X; Kaplan DL, 2015, 'Vascularization of Bioengineered Tissues: Additive Effects of Physical and Biological Cues', in TISSUE ENGINEERING PART A, MARY ANN LIEBERT, INC, Boston, MA, pp. S114 - S115, presented at 4th TERMIS World Congress, Boston, MA, 08 September 2015 - 11 September 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360205201050&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Patents |
    Dr Jelena Rnjak-Kovacina
    Wray, L ; Rnjak-Kovacina J; Kaplan DL, Silk-based scaffold for vascularizing engineered tissue construct comprises body containing hollow conduits disposed in a solid-state silk matrix, where the hollow conduits are arranged in a pre-determined pattern, Patent No. WO2013070907-A1

Awards

 

  • NSW Early Career Researcher of the Year (Physical Sciences), NSW Premier's Prizes for Science & Engineering, 2020
  • Emerging Leader Award, Australasian Society for Biomaterials and Tissue Engineering (ABSTE), 2019
  • Travel award- NSW CVRN Travel Scholarship application, 2018
  • NSW Young Tall Poppy Science Award, Australian Institute of Policy & Science, 2018
  • Bob Fraser New Investigator Award, Matrix Biology Society of Australia & NZ, 2016
  • Fresh Science NSW, 2016
  • Finalist (Top 19) in the L’Oreal Women in Science Fellowship, 2015
  • Research featured in the American Chemical Society (ACS) Headline Science video series, 2015
  • Travel Award- Contributing to Australian Scholarship and Science (CASS) Foundation, 2015
  • Travel Award- Australasian Society for Biomaterials & Tissue Engineering (ASBTE), 2015
  • American Chemical Society (ACS) Editors’ Choice article, 2015
  • Best Early Career Researcher Oral Presentation Award- ASBTE, 2013
  • Best poster prize- ASBTE, 2009;
  • Best poster prize- 34th Lorne Conference on Protein Structure & Function, 2009
  • University Medal, University of Sydney, 2006.             

 

 

Grants

 

  • NSW Health/Cardiovascular Research Capacity Program - Investigator Development Grants (lead CI), ‘Engineering vascular microenvironments on silk biomaterials for advanced medical implants’, 2020
  • Australia-Germany Joint Research Cooperation Scheme (DAAD) (lead CI), ‘Application of advanced scaffold fabrication technologies toward functional cardiac patches’, 2020-2021
  • ARC Linkage Project (co-CI), ‘Engineering a physiologically-relevant blood vessel in vitro’, 2019-2022
  • Innovative Manufacturing CRC (co-CI), ‘Engineering an advanced, high value bioreactor system for research and clinical applications’, 2019-2022
  • HRC Project Grant (PI), ‘Smart delivery of growth factors for treating osteonecrosis of the femoral head’, 2021-2022
  • HRC Sir Charles Hercules Health Research Fellowship (AI), ‘HRC Sir Charles Hercus Health Research Fellowship’, 2020-2022
  • MARSDEN Fast start (PI), ‘Harnessing macromolecular chemistry to mimic vascular developmental biology’, 2020-2021
  • NHMRC Project Grant (co-CI), ‘New Synthetic Conduits for Arterial Revascularisation’ 2019-2021, Marshall and Warren Award for the most innovative and potentially transformative project grant
  • Diabetes Australia (co-CI), ‘Bioengineered growth factor binding scaffolds for improved diabetic wound healing’, 2019
  • Heart Foundation Future Leader Fellowship (lead CI), ‘Biomaterial-directed vascularisation of bioengineered cardiac patches’, 2018-2022
  • ARC Discovery Project (DP150104242) (lead CI), ‘Novel biomimetic vascular biomaterials using extracellular matrix molecules’, 2015-2019;
  • UNSW Engineering Faculty Major Research Equipment Funding (lead CI), 'Medical device characterisation', 2018
  • UNSW Infrastructure Fund (AI), ‘Dynamic Mechanical Testing-ElectroForce’, 2017
  • UNSW Infrastructure Fund (AI), ‘High throughput Flash Purification System for Small Molecule and Polymer Separations’, 2017;
  • UNSW Network Lab Project (AI), ‘Molecular Surface Interaction Network Lab’, 2017-2018;
  • UNSW Faculty of Engineering Startup award (lead CI), 2016-2017;
  • UNSW Career Advancement Fund (lead CI), 2017-2018;
  • UNSW Minor Equipment Grants (lead CI), 2014, 2015, 2016, 2017;
  • UNSW Faculty of Engineering Early Career Researcher Award (lead CI), 2014.

Media