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McLean B; Istadi A; Clack T; Vankan M; Schramek D; Neely GG; Pajic M, 2022, 'A CRISPR Path to Finding Vulnerabilities and Solving Drug Resistance: Targeting the Diverse Cancer Landscape and Its Ecosystem.', Adv Genet (Hoboken), 3, pp. 2200014, http://dx.doi.org/10.1002/ggn2.202200014
Journal articles | 2022
Poh AR; O'Brien M; Chisanga D; He H; Baloyan D; Traichel J; Dijkstra C; Chopin M; Nutt S; Whitehead L; Boon L; Parkin A; Lowell C; Pajic M; Shi W; Nikfarjam M; Ernst M, 2022, 'Inhibition of HCK in myeloid cells restricts pancreatic tumor growth and metastasis', Cell Reports, 41, http://dx.doi.org/10.1016/j.celrep.2022.111479
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Dreyer SB; Upstill-Goddard R; Paulus-Hock V; Paris C; Lampraki EM; Dray E; Serrels B; Caligiuri G; Rebus S; Plenker D; Galluzzo Z; Brunton H; Cunningham R; Tesson M; Nourse C; Bailey UM; Jones MD; Moran-Jones K; Wright DW; Duthie F; Oien K; Evers L; McKay CJ; McGregor GA; Gulati A; Brough R; Bajrami I; Pettitt S; Dziubinski ML; Candido J; Balkwill F; Barry ST; Grützmann R; Rahib L; Allison S; Bailey PJ; Biankin AV; Beraldi D; Cameron E; Chang DK; Cooke SL; Grimwood P; Kelly S; Marshall J; Martin S; McDade B; McElroy D; Musgrove EA; Ramsay D; Wright D; Hair J; Jamieson NB; Westwood P; Williams N; Johns AL; Mawson A; Scarlett CJ; Brancato MAL; Rowe SJ; Simpson SH; Martyn-Smith M; Thomas MT; Chantrill LA; Chin VT; Chou A; Cowley MJ; Humphris JL; Mead RS; Nagrial AM; Pajic M; Pettit J; Pinese M; Rooman I; Wu J; Tao J; DiPietro R; Watson C; Steinmann A; Lee HC; Wong R; Pinho AV; Giry-Laterriere M; Daly RJ; Sutherland RL; Grimmond SM; Waddell N; Kassahn KS; Miller DK; Wilson PJ; Patch AM; Song S; Harliwong I; Idrisoglu S; Nourbakhsh E; Manning S; Wani S; Gongora M; Anderson M; Holmes O; Leonard C, 2021, 'Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer', Gastroenterology, 160, pp. 362 - 377.e13, http://dx.doi.org/10.1053/j.gastro.2020.09.043
Journal articles | 2021
Geleta B; Park KC; Jansson PJ; Sahni S; Maleki S; Xu Z; Murakami T; Pajic M; Apte MV; Richardson DR; Kovacevic Z, 2021, 'Breaking the cycle: Targeting of NDRG1 to inhibit bi-directional oncogenic cross-talk between pancreatic cancer and stroma', FASEB Journal, 35, pp. e21347, http://dx.doi.org/10.1096/fj.202002279R
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Kryza T; Khan T; Lovell S; Harrington BS; Yin J; Porazinski S; Pajic M; Koistinen H; Rantala JK; Dreyer T; Magdolen V; Reuning U; He Y; Tate EW; Hooper JD, 2021, 'Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1', Nature Chemical Biology, 17, pp. 776 - 783, http://dx.doi.org/10.1038/s41589-021-00783-w
Lundy J; Gearing LJ; Gao H; West AC; McLeod L; Deswaerte V; Yu L; Porazinski S; Pajic M; Hertzog PJ; Croagh D; Jenkins BJ, 2021, 'TLR2 activation promotes tumour growth and associates with patient survival and chemotherapy response in pancreatic ductal adenocarcinoma', Oncogene, 40, pp. 6007 - 6022, http://dx.doi.org/10.1038/s41388-021-01992-2
Journal articles | 2021
Murphy KJ; Reed DA; Vennin C; Conway JRW; Nobis M; Yin JX; Chambers CR; Pereira BA; Lee V; Filipe EC; Trpceski M; Ritchie S; Lucas MC; Warren SC; Skhinas JN; Magenau A; Metcalf XL; Stoehr J; Major G; Parkin A; Bidanel R; Lyons RJ; Zaratzian A; Tayao M; Da Silva A; Abdulkhalek L; Gill AJ; Johns AL; Biankin AV; Samra J; Grimmond SM; Chou A; Goetz JG; Samuel MS; Lyons JG; Burgess A; Caldon CE; Horvath LG; Daly RJ; Gadegaard N; Wang Y; Sansom OJ; Morton JP; Cox TR; Pajic M; Herrmann D; Timpson P, 2021, 'Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status', Science Advances, 7, http://dx.doi.org/10.1126/sciadv.abh0363
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Satgunaseelan L; Porazinski S; Strbenac D; Istadi A; Willet C; Chew T; Sadsad R; Palme CE; Lee JH; Boyer M; Yang JYH; Clark JR; Pajic M; Gupta R, 2021, 'Oral Squamous Cell Carcinoma in Young Patients Show Higher Rates of EGFR Amplification: Implications for Novel Personalized Therapy', Frontiers in Oncology, 11, pp. 750852, http://dx.doi.org/10.3389/fonc.2021.750852
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Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2021, 'Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to slc7a11 inhibition', Cancer Research, 81, pp. 3461 - 3479, http://dx.doi.org/10.1158/0008-5472.CAN-20-2496
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Brunton H; Caligiuri G; Cunningham R; Upstill-Goddard R; Bailey UM; Garner IM; Nourse C; Dreyer S; Jones M; Moran-Jones K; Wright DW; Paulus-Hock V; Nixon C; Thomson G; Jamieson NB; McGregor GA; Evers L; McKay CJ; Gulati A; Brough R; Bajrami I; Pettitt SJ; Dziubinski ML; Barry ST; Grützmann R; Brown R; Curry E; Allison S; Biankin AV; Chang DK; Cooke SL; Grimwood P; Kelly S; Marshall J; McDade B; McElroy D; Ramsay D; Rebus S; Hair J; Westwood P; Williams N; Duthie F; Johns AL; Mawson A; Scarlett CJ; Brancato MAL; Rowe SJ; Simpson SH; Martyn-Smith M; Thomas MT; Chantrill LA; Chin VT; Chou A; Cowley MJ; Humphris JL; Mead RS; Nagrial AM; Pajic M; Pettit J; Pinese M; Rooman I; Wu J; Tao J; DiPietro R; Watson C; Steinmann A; Lee HC; Wong R; Pinho AV; Giry-Laterriere M; Daly RJ; Musgrove EA; Sutherland RL; Grimmond SM; Waddell N; Kassahn KS; Miller DK; Wilson PJ; Patch AM; Song S; Harliwong I; Idrisoglu S; Nourbakhsh E; Manning S; Wani S; Gongora M; Anderson M; Holmes O; Leonard C; Taylor D; Wood S; Xu C; Nones K; Fink JL; Christ A; Bruxner T; Cloonan N; Newell F; Pearson JV; Quinn M, 2020, 'HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer', Cell Reports, 31, http://dx.doi.org/10.1016/j.celrep.2020.107625
Man J; Pajic M; Joshua AM, 2020, 'Fats and mets, KRAS-driven lipid dysregulation affects metastatic potential in pancreatic cancer', Cancer Research, 80, pp. 4886 - 4887, http://dx.doi.org/10.1158/0008-5472.CAN-20-3082
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Porazinski S; Parkin A; Pajic M, 2020, 'Rho-ROCK Signaling in Normal Physiology and as a Key Player in Shaping the Tumor Microenvironment', , 1223, pp. 99 - 127, http://dx.doi.org/10.1007/978-3-030-35582-1_6
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Thejer BM; Adhikary PP; Kaur A; Teakel SL; Van Oosterum A; Seth I; Pajic M; Hannan KM; Pavy M; Poh P; Jazayeri JA; Zaw T; Pascovici D; Ludescher M; Pawlak M; Cassano JC; Turnbull L; Jazayeri M; James AC; Coorey CP; Roberts TL; Kinder SJ; Hannan RD; Patrick E; Molloy MP; New EJ; Fehm TN; Neubauer H; Goldys EM; Weston LA; Cahill MA, 2020, 'PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth', BMC Molecular and Cell Biology, 21, pp. 24, http://dx.doi.org/10.1186/s12860-020-00256-3
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Vennin C; Rath N; Pajic M; Olson MF; Timpson P, 2020, 'Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy', Small GTPases, 11, pp. 45 - 52, http://dx.doi.org/10.1080/21541248.2017.1345712
Journal articles | 2019
Blatter S; Pajic M; Guyader C; Gonggrijp M; Kersbergen A; Küçükosmanoğlu A; Sol W; Drost R; Jonkers J; Borst P; Rottenberg S, 2019, 'Targeting drug tolerance of residual BRCA1-mutated mouse mammary tumours', Journal of Comparative Pathology, 166, pp. 101 - 101, http://dx.doi.org/10.1016/j.jcpa.2018.10.008
Parkin A; Man J; Timpson P; Pajic M, 2019, 'Targeting the complexity of Src signalling in the tumour microenvironment of pancreatic cancer: from mechanism to therapy', FEBS Journal, 286, pp. 3510 - 3539, http://dx.doi.org/10.1111/febs.15011
Journal articles | 2019
Wang K; Huynh N; Wang X; Pajic M; Parkin A; Man J; Baldwin GS; Nikfarjam M; He H, 2019, 'PAK inhibition by PF-3758309 enhanced the sensitivity of multiple chemotherapeutic reagents in patient-derived pancreatic cancer cell lines', American Journal of Translational Research, 11, pp. 3353 - 3364, https://www.ncbi.nlm.nih.gov/pubmed/31312349
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Campbell H; Fleming N; Roth I; Mehta S; Wiles A; Williams G; Vennin C; Arsic N; Parkin A; Pajic M; Munro F; McNoe L; Black M; McCall J; Slatter TL; Timpson P; Reddel R; Roux P; Print C; Baird MA; Braithwaite AW, 2018, 'Δ133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signaling', Nature Communications, 9, http://dx.doi.org/10.1038/s41467-017-02408-0
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Chou A; Kim Y; Samra JS; Pajic M; Gill AJ, 2018, 'BRAF gene rearrangements can be identified by FISH studies in pancreatic acinar cell carcinoma', Pathology, 50, pp. 345 - 348, http://dx.doi.org/10.1016/j.pathol.2017.09.027
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Conway JRW; Warren SC; Herrmann D; Murphy KJ; Cazet AS; Vennin C; Shearer RF; Killen MJ; Magenau A; Mélénec P; Pinese M; Nobis M; Zaratzian A; Boulghourjian A; Da Silva AM; del Monte-Nieto G; Adam ASA; Harvey RP; Haigh JJ; Wang Y; Croucher DR; Sansom OJ; Pajic M; Caldon CE; Morton JP; Timpson P, 2018, 'Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer', Cell Reports, 23, pp. 3312 - 3326, http://dx.doi.org/10.1016/j.celrep.2018.05.038
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Hoque M; Abbassi RH; Froio D; Man J; Johns TG; Stringer BW; Day BW; Pajic M; Kassiou M; Munoz L, 2018, 'Changes in cell morphology guide identification of tubulin as the off-target for protein kinase inhibitors', Pharmacological Research, 134, pp. 166 - 178, http://dx.doi.org/10.1016/j.phrs.2018.06.023
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Molloy T; Parkin A; Chou A; Samra J; Timpson P; Gill A; Pajic M, 2018, 'PO-195 Integrative analysis of in vivo models of pancreatic cancer reveals complex mechanisms behind treatment failure and provides new tools for effective targeting', ESMO Open, 3, pp. A303 - A303, http://dx.doi.org/10.1136/esmoopen-2018-eacr25.713
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Murphy K; Vennin C; Cox T; Wang Y; Morton J; Sansom O; Pajic M; Herrmann D; Timpson P, 2018, 'PO-229 Transient tissue ‘priming’ via FAK inhibition to impair pancreatic ductal adenocarcinoma (PDAC) progression to improve sensitivity to gemcitabine/abraxane', ESMO Open, 3, pp. A316 - A317, http://dx.doi.org/10.1136/esmoopen-2018-eacr25.746
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Parkin A; Man J; Chou A; Nagrial AM; Samra J; Gill AJ; Timpson P; Pajic M, 2018, 'The Evolving Understanding of the Molecular and Therapeutic Landscape of Pancreatic Ductal Adenocarcinoma.', Diseases, 6, http://dx.doi.org/10.3390/diseases6040103
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Parkin A; Steinmann A; Froio D; Drury A; Vogel N; Murphy K; Deng N; Gill A; Timpson P; Pajic M, 2018, 'PO-046 Dual inhibition of JAK and Src: a novel and promising therapeutic combination for pancreatic cancer', ESMO Open, 3, pp. A245 - A245, http://dx.doi.org/10.1136/esmoopen-2018-eacr25.579
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Rath N; Munro J; Cutiongco MF; Jagiełło A; Gadegaard N; McGarry L; Unbekandt M; Michalopoulou E; Kamphorst JJ; Sumpton D; Mackay G; Vennin C; Pajic M; Timpson P; Olson MF, 2018, 'Rho kinase inhibition by AT13148 blocks pancreatic ductal adenocarcinoma invasion and tumor growth', Cancer Research, 78, pp. 3321 - 3336, http://dx.doi.org/10.1158/0008-5472.CAN-17-1339
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Vennin C; Murphy KJ; Morton JP; Cox TR; Pajic M; Timpson P, 2018, 'Reshaping the Tumor Stroma for Treatment of Pancreatic Cancer', Gastroenterology, 154, pp. 820 - 838, http://dx.doi.org/10.1053/j.gastro.2017.11.280
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Chin VT; Vennin C; Timpson P; Pajic M, 2017, 'Effective modulation of stromal signaling through ROCK inhibition: Is it all in the timing?', Molecular and Cellular Oncology, 4, http://dx.doi.org/10.1080/23723556.2017.1333973
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Vennin C; Cox TR; Pajic M; Timpson P, 2017, 'Transient targeting of the pancreatic cancer stroma as a 'finetuned' anti-tumor and anti-metastatic therapy', Oncotarget, 8, pp. 84635 - 84636, http://dx.doi.org/10.18632/oncotarget.21468
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Chou A; Steinmann A; Froio D; Drury A; Wohl D; Chin V; Nagrial A; Gill A; Pajic M, 2016, 'Combination of CDK4/6 inhibitor PD-0332991 with standard chemotherapy is synergistic in RB high pancreatic cancer', European Journal of Cancer, 61, pp. S182 - S182, http://dx.doi.org/10.1016/s0959-8049(16)61645-3
Journal articles | 2016
Gingras MC; Covington KR; Chang DK; Donehower LA; Gill AJ; Ittmann MM; Creighton CJ; Johns AL; Shinbrot E; Dewal N; Fisher WE; Pilarsky C; Grützmann R; Overman MJ; Jamieson NB; Van Buren G; Drummond J; Walker K; Hampton OA; Xi L; Muzny DM; Doddapaneni H; Lee SL; Bellair M; Hu J; Han Y; Dinh HH; Dahdouli M; Samra JS; Bailey P; Waddell N; Pearson JV; Harliwong I; Wang H; Aust D; Oien KA; Hruban RH; Hodges SE; McElhany A; Saengboonmee C; Duthie FR; Grimmond SM; Biankin AV; Wheeler DA; Gibbs RA; Jones MD; Mawson A; Scarlett CJ; Brancato MAL; Rowe SJ; Simpson SH; Smith Martyn M; Thomas MT; Chantrill LA; Chin VT; Angela C; Cowley MJ; Humphris JL; Mead S; Nagrial AM; Pajic M; Pettit J; Pinese M; Rooman I; Wu J; Tao J; DiPietro R; Watson C; Steinmann A; Lee HC; Wong R; Pinho AV; Giry-Laterriere M; Daly RJ; Musgrove EA; Sutherland RL; Kassahn KS; Miller DK; Wilson PJ; Patch AM; Song S; Idrisoglu S; Nourse C; Nourbakhsh E; Manning S; Wani S; Gongora M; Anderson M; Holmes O; Leonard C; Taylor D; Wood S; Xu C; Nones K; Fink LJ; Christ A; Bruxner T; Cloonan N; Newell F; Quinn M, 2016, 'Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation', Cell Reports, 14, pp. 907 - 919, http://dx.doi.org/10.1016/j.celrep.2015.12.005
Journal articles | 2016
Humphrey ES; Su SP; Nagrial AM; Hochgrä Fe F; Pajic M; Lehrbach GM; Parton RG; Yap AS; Horvath LG; Chang DK; Biankin AV; Wu J; Daly RJ, 2016, 'Resolution of novel pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling', Molecular and Cellular Proteomics, 15, pp. 2671 - 2685, http://dx.doi.org/10.1074/mcp.M116.058313
Journal articles | 2016
O'Connor LO; Rulten SL; Cranston AN; Odedra R; Brown H; Jaspers JE; Jones L; Knights C; Evers B; Ting A; Bradbury RH; Pajic M; Rottenberg S; Jonkers J; Rudge D; Martin NMB; Caldecott KW; Lau A; O'Connor MJ, 2016, 'The PARP inhibitor AZD2461 provides insights into the role of PARP3 inhibition for both synthetic lethality and tolerability with chemotherapy in preclinical models', Cancer Research, 76, pp. 6084 - 6094, http://dx.doi.org/10.1158/0008-5472.CAN-15-3240
Journal articles | 2015
Chantrill LA; Nagrial AM; Watson C; Johns AL; Martyn-Smith M; Simpson S; Mead S; Jones MD; Samra JS; Gill AJ; Watson N; Chin VT; Humphris JL; Chou A; Brown B; Morey A; Pajic M; Grimmond SM; Chang DK; Thomas D; Sebastian L; Sjoquist K; Yip S; Pavlakis N; Asghari R; Harvey S; Grimison P; Simes J; Biankin AV, 2015, 'Precision medicine for advanced pancreas cancer: The individualized molecular pancreatic cancer therapy (IMPaCT) Trial', Clinical Cancer Research, 21, pp. 2029 - 2037, http://dx.doi.org/10.1158/1078-0432.CCR-15-0426
Journal articles | 2015
Chin VT; Nagrial AM; Chou A; Biankin AV; Gill AJ; Timpson P; Pajic M, 2015, 'Rho-associated kinase signalling and the cancer microenvironment: Novel biological implications and therapeutic opportunities', Expert Reviews in Molecular Medicine, 17, http://dx.doi.org/10.1017/erm.2015.17
Journal articles | 2015
Grimont A; Pinho AV; Cowley MJ; Augereau C; Mawson A; Giry-Laterriere M; Van den Steen G; Waddell N; Pajic M; Sempoux C; Wu J; Grimmond SM; Biankin AV; Lemaigre FP; Rooman I; Jacquemin P, 2015, 'SOX9 regulates ERBB signalling in pancreatic cancer development', GUT, 64, pp. 1790 - 1799, http://dx.doi.org/10.1136/gutjnl-2014-307075
Journal articles | 2015
Nagrial AM; Chin VT; Sjoquist KM; Pajic M; Horvath LG; Biankin AV; Yip D, 2015, 'Second-line treatment in inoperable pancreatic adenocarcinoma: A systematic review and synthesis of all clinical trials', Critical Reviews in Oncology/Hematology, 96, pp. 483 - 497, http://dx.doi.org/10.1016/j.critrevonc.2015.07.007
Journal articles | 2015
Pajic M; Herrmann D; Vennin C; Conway JRW; Chin VT; Johnsson AKE; Welch HCE; Timpson P, 2015, 'The dynamics of Rho GTPase signaling and implications for targeting cancer and the tumor microenvironment', Small GTPases, 6, pp. 123 - 133, http://dx.doi.org/10.4161/21541248.2014.973749
Journal articles | 2015
Susanto JM; Colvin EK; Pinese M; Chang DK; Pajic M; Mawson A; Caldon CE; Musgrove EA; Henshall SM; Sutherland RL; Biankin AV; Scarlett CJ, 2015, 'The epigenetic agents suberoylanilide hydroxamic acid and 5-AZA-2′ deoxycytidine decrease cell proliferation, induce cell death and delay the growth of MiaPaCa2 pancreatic cancer cells in vivo', International Journal of Oncology, 46, pp. 2223 - 2230, http://dx.doi.org/10.3892/ijo.2015.2894
Journal articles | 2015
Vennin C; Pajic M; Timpson P, 2015, 'Imaging fibrosis in pancreatic cancer using second harmonic generation', Pancreatology, 15, pp. 200 - 201, http://dx.doi.org/10.1016/j.pan.2015.02.004
Journal articles | 2015
Waddell N; Pajic M; Patch AM; Chang DK; Kassahn KS; Bailey P; Johns AL; Miller D; Nones K; Quek K; Quinn MCJ; Robertson AJ; Fadlullah MZH; Bruxner TJC; Christ AN; Harliwong I; Idrisoglu S; Manning S; Nourse C; Nourbakhsh E; Wani S; Wilson PJ; Markham E; Cloonan N; Anderson MJ; Fink JL; Holmes O; Kazakoff SH; Leonard C; Newell F; Poudel B; Song S; Taylor D; Waddell N; Wood S; Xu Q; Wu J; Pinese M; Cowley MJ; Lee HC; Jones MD; Nagrial AM; Humphris J; Chantrill LA; Chin V; Steinmann AM; Mawson A; Humphrey ES; Colvin EK; Chou A; Scarlett CJ; Pinho AV; Giry-Laterriere M; Rooman I; Samra JS; Kench JG; Pettitt JA; Merrett ND; Toon C; Epari K; Nguyen NQ; Barbour A; Zeps N; Jamieson NB; Graham JS; Niclou SP; Bjerkvig R; Grützmann R; Aust D; Hruban RH; Maitra A; Iacobuzio-Donahue CA; Wolfgang CL; Morgan RA; Lawlor RT; Corbo V; Bassi C; Falconi M; Zamboni G; Tortora G; Tempero MA; Gill AJ; Eshleman JR; Pilarsky C; Scarpa A; Musgrove EA; Pearson JV; Biankin AV; Grimmond SM, 2015, 'Whole genomes redefine the mutational landscape of pancreatic cancer', Nature, 518, pp. 495 - 501, http://dx.doi.org/10.1038/nature14169
Journal articles | 2014
Al-Ejeh F; Pajic M; Shi W; Kalimutho M; Miranda M; Nagrial AM; Chou A; Biankin AV; Grimmond SM; Brown MP; Khanna KK, 2014, 'Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinoma', Clinical Cancer Research, 20, pp. 3187 - 3197, http://dx.doi.org/10.1158/1078-0432.CCR-14-0048
Journal articles | 2014
Chou A; Gill AJ; Kang J; Lee C; Sergio M; APGI ; Musgrove L; Morey AL; Grimmond S; Biankin AV; Pajic M, 2014, '9. Cyclin-Dependent kinase inhibitor as a potential novel therapeutic agent for pancreatic cancer', Pathology, 46, pp. S109 - S109, http://dx.doi.org/10.1097/01.pat.0000443699.20071.3b
Journal articles | 2014
Grimont A; Pinho AV; Cowley MJ; Augereau C; Mawson A; Giry-Laterriere M; Van den Steen G; Waddell N; Pajic M; Sempoux C; Wu J; Grimmond SM; Biankin AV; Lemaigre FP; Rooman I; Jacquemin P, 2014, 'SOX9 regulates ERBB signalling in pancreatic cancer development', Gut, 64, pp. 1790 - 1799, http://dx.doi.org/10.1136/gutjnl-2014-307075
Journal articles | 2014
Humphris JL; Johns AL; Simpson SH; Cowley MJ; Pajic M; Chang DK; Nagrial AM; Chin VT; Chantrill LA; Pinese M; Mead RS; Gill AJ; Samra JS; Kench JG; Musgrove EA; Tucker KM; Spigelman AD; Waddell N; Grimmond SM; Biankin AV, 2014, 'Clinical and pathologic features of familial pancreatic cancer', Cancer, 120, pp. 3669 - 3675, http://dx.doi.org/10.1002/cncr.28863
Journal articles | 2014
Johns AL; Miller DK; Simpson SH; Gill AJ; Kassahn KS; Humphris JL; Samra JS; Tucker K; Andrews L; Chang DK; Waddell N; Pajic M; Pearson JV; Grimmond SM; Biankin AV; Zeps N; Martyn-Smith M; Tang H; Papangelis V; Beilin M, 2014, 'Returning individual research results for genome sequences of pancreatic cancer', Genome Medicine, 6, http://dx.doi.org/10.1186/gm558
Journal articles | 2014
Kemp MW; Molloy TJ; Pajic M; Chapman E, 2014, 'An analysis of reported motivational orientation in students undertaking doctoral studies in the biomedical sciences', BMC Medical Education, 14, http://dx.doi.org/10.1186/1472-6920-14-38
Journal articles | 2014
Nagrial AM; Chang DK; Nguyen NQ; Johns AL; Chantrill LA; Humphris JL; Chin VT; Samra JS; Gill AJ; Pajic M; Pinese M; Colvin EK; Scarlett CJ; Chou A; Kench JG; Sutherland RL; Horvath LG; Biankin AV, 2014, 'Adjuvant chemotherapy in elderly patients with pancreatic cancer', British Journal of Cancer, 110, pp. 313 - 319, http://dx.doi.org/10.1038/bjc.2013.722
Journal articles | 2014
Nones K; Waddell N; Song S; Patch AM; Miller D; Johns A; Wu J; Kassahn KS; Wood D; Bailey P; Fink L; Manning S; Christ AN; Nourse C; Kazakoff S; Taylor D; Leonard C; Chang DK; Jones MD; Thomas M; Watson C; Pinese M; Cowley M; Rooman I; Pajic M; Butturini G; Malpaga A; Corbo V; Crippa S; Falconi M; Zamboni G; Castelli P; Lawlor RT; Gill AJ; Scarpa A; Pearson JV; Biankin AV; Grimmond SM, 2014, 'Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling', International Journal of Cancer, 135, pp. 1110 - 1118, http://dx.doi.org/10.1002/ijc.28765
Journal articles | 2014
Sjoquist KM; Chin VT; Chantrill LA; O'Connor C; Hemmings C; Chang DK; Chou A; Pajic M; Johns AL; Nagrial AM; Biankin AV; Yip D, 2014, 'Personalising pancreas cancer treatment: When tissue is the issue', World Journal of Gastroenterology, 20, pp. 7849 - 7863, http://dx.doi.org/10.3748/wjg.v20.i24.7849
Journal articles | 2013
Alexandrov LB; Nik-Zainal S; Wedge DC; Aparicio SAJR; Behjati S; Biankin AV; Bignell GR; Bolli N; Borg A; Børresen-Dale A-L; Boyault S; Burkhardt B; Butler AP; Caldas C; Davies HR; Desmedt C; Eils R; Eyfjörd JE; Foekens JA; Greaves M; Hosoda F; Hutter B; Ilicic T; Imbeaud S; Imielinski M; Jäger N; Jones DTW; Knappskog S; Kool M; Lakhani SR; López-Otín C; Martin S; Munshi NC; Nakamura H; Northcott PA; Pajic M; Papaemmanuil E; Paradiso A; Pearson JV; Puente XS; Raine K; Ramakrishna M; Richardson AL; Richter J; Rosenstiel P; Schlesner M; Schumacher TN; Span PN; Teague JW; Totoki Y; Tutt ANJ; Valdés-Mas R; Van Buuren MM; Van 'T Veer L; Vincent-Salomon A; Waddell N; Yates LR; Zucman-Rossi J; Futreal PA; McDermott U; Lichter P; Meyerson M; Grimmond SM; Siebert R; Campo E; Shibata T; Pfister SM; Campbell PJ; Stratton MR, 2013, 'Erratum: Signatures of mutational processes in human cancer', Nature, 502, pp. 258 - 258, http://dx.doi.org/10.1038/nature12666
Journal articles | 2013
Alexandrov LB; Nik-Zainal S; Wedge DC; Aparicio SAJR; Behjati S; Biankin AV; Bignell GR; Bolli N; Borg A; Børresen-Dale AL; Boyault S; Burkhardt B; Butler AP; Caldas C; Davies HR; Desmedt C; Eils R; Eyfjörd JE; Foekens JA; Greaves M; Hosoda F; Hutter B; Ilicic T; Imbeaud S; Imielinsk M; Jäger N; Jones DTW; Jonas D; Knappskog S; Koo M; Lakhani SR; López-Otín C; Martin S; Munshi NC; Nakamura H; Northcott PA; Pajic M; Papaemmanuil E; Paradiso A; Pearson JV; Puente XS; Raine K; Ramakrishna M; Richardson AL; Richter J; Rosenstiel P; Schlesner M; Schumacher TN; Span PN; Teague JW; Totoki Y; Tutt ANJ; Valdés-Mas R; Van Buuren MM; Van 'T Veer L; Vincent-Salomon A; Waddell N; Yates LR; Zucman-Rossi J; Andrew Futreal P; McDermott U; Lichter P; Meyerson M; Grimmond SM; Siebert R; Campo E; Shibata T; Pfister SM; Campbell PJ; Stratton MR, 2013, 'Signatures of mutational processes in human cancer', Nature, 500, pp. 415 - 421, http://dx.doi.org/10.1038/nature12477
Journal articles | 2013
Chang DK; Jamieson N; Johns A; Scarlett CJ; Pajic M; Biankin AV; et A, 2013, 'Histomolecular phenotypes and outcome in adenocarcinoma of the ampulla of vater', Journal of Clinical Oncology, 31, pp. 1348 - 1356, http://dx.doi.org/10.1200/JCO.2012.46.8868
Journal articles | 2013
Chin VT; Nagrial A; Chantrill LA; Chang DK; Chou A; Humprhis J; Cowley M; Wu J; DiPetro R; Watson C; Spielman C; Steinmann A; Pinese M; Pettitt J; Johns A; Waddell N; Grimmond S; Timpson P; Biankin AV; Pajic M, 2013, 'From functional genomics to precision medicine: The therapeutic potential of targeting ROCK signaling in pancreatic cancer.', Journal of Clinical Oncology, 31, pp. e15029 - e15029, http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e15029
Kassahn KS; Holmes O; Nones K; Patch AM; Miller DK; Christ AN; Harliwong I; Bruxner TJ; Xu Q; Anderson M; Wood S; Leonard C; Taylor D; Newell F; Song S; Idrisoglu S; Nourse C; Nourbakhsh E; Manning S; Wani S; Steptoe A; Pajic M; Cowley MJ; Pinese M; Chang DK; Gill AJ; Johns AL; Wu J; Wilson PJ; Fink L; Biankin AV; Waddell N; Grimmond SM; Pearson JV, 2013, 'Somatic point mutation calling in low cellularity tumors', PLoS ONE, 8, http://dx.doi.org/10.1371/journal.pone.0074380
Journal articles | 2013
Kemp MW; Molloy TJ; Pajic M; Chapman E, 2013, 'Peer relationships and the biomedical doctorate: A key component of the contemporary learning environment', Journal of Higher Education Policy and Management, 35, pp. 370 - 385, http://dx.doi.org/10.1080/1360080X.2013.812055
Journal articles | 2013
Kemp MW; Pajic M; Molloy TJ; Chapman E, 2013, 'Perceived assessment requirements in the contemporary biomedical doctorate: A case-study from a research intensive australian university', International Journal of Doctoral Studies, 8, pp. 105 - 120, http://dx.doi.org/10.28945/1893
Journal articles | 2012
Harliwong I; Gudkov AV; De Ridder J; Burkhart CA; Knosel T; Rummele P; Pajic M; Sartorelli AC; van der Weyden L, 2012, 'Impact of intertumoral heterogeneity on predicting chemotheraphy response of BRCA1-deficient mammary tumors', Cancer Research, 72, pp. 2350 - 2361, http://dx.doi.org/10.1158/0008-5472.CAN-11-4201
Journal articles | 2012
Perez-Mancera P; Rust AG; van der Weyden L; Kristiansen GO; Kristiansen GO; Li A; Sarver AL; Silverstein KAT; Grutzmann R; Aust DE; Rummele P; Knosel T; Herd C; Stemple D; Kettleborough R; Brosnan JA; Li A; Richard GM; Knight S; Yu J; Stegeman S; Collier LS; Ten Hoeve JJ; De Ridder J; Klein A; Goggins M; Hruban R; Chang D; Biankin AV; Pinese M; Grimmond S; Wessels L; Wood S; Iacobuzio-donahue CA; Pilarsky CP; Largaespada DA; Adams DJ; Tuveson DA, 2012, 'The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma', Nature, 486, pp. 266 - 270, http://dx.doi.org/10.1038/nature11114
Journal articles | 2012
Song S; Nones K; Miller DK; Harliwong I; Pinese M; Kassahn KS; Pajic M; Gill A; Johns A; Anderson ML; Holmes O; Leonard C; Taylor DF; Wood SA; Xu Q; Newell FS; Cowley MJ; Wu J; Wilson PJ; Fink L; Biankin AV; Waddell NJ; Grimmond S; Pearson JV, 2012, 'qpure: A tool to estimate tumor cellularity from genome-wide single-nucleotide polymorphism profiles', PLoS ONE, 7, pp. e45835, http://dx.doi.org/10.1371/journal.pone.0045835
Journal articles | 2011
Chang DK; Colvin EK; Scarlett CJ; Pajic M; Pinese M; Gill AJ; Musgrove EA; Sutherland R; Kench J; Biankin AV; New South Wales Pancreatic Cancer Network , 2011, 'A molecular prognostic nomogram for resectable pancreatic cancer.', J Clin Oncol, 29, pp. 154, http://www.ncbi.nlm.nih.gov/pubmed/27985628
Journal articles | 2011
Chang DK; Colvin EK; Scarlett CJ; Pajic M; Pinese M; Gill AJ; Musgrove EA; Sutherland R; Kench J; Biankin AV, 2011, 'A molecular prognostic nomogram for resectable pancreatic cancer', JOURNAL OF CLINICAL ONCOLOGY, 29, http://dx.doi.org/10.1200/jco.2011.29.4_suppl.154
Journal articles | 2011
Chang DK; Johns A; Scarlett CJ; Pajic M; Chou A; Toon C; Samra JS; Sutherland R; Gill AJ; Biankin AV; New South Wales Pancreatic Cancer Network , 2011, 'Molecular pathologic phenotypes and outcome in adenocarcinoma of the ampulla of Vater.', J Clin Oncol, 29, pp. 196, http://www.ncbi.nlm.nih.gov/pubmed/27985359
Journal articles | 2011
Chang DK; Johns A; Scarlett CJ; Pajic M; Chou A; Toon C; Samra JS; Sutherland R; Gill AJ; Biankin AV, 2011, 'Molecular pathologic phenotypes and outcome in adenocarcinoma of the ampulla of Vater', JOURNAL OF CLINICAL ONCOLOGY, 29, http://dx.doi.org/10.1200/jco.2011.29.4_suppl.196
Journal articles | 2010
Borst P; Rottenberg S; Jonkers J; Zander S; Pajic M; Jaspers J, 2010, 'The contribution of ABC transporters to drug resistance in a realistic mouse mammary tumor model', Cancer Genetics and Cytogenetics, 203, pp. 64 - 64, http://dx.doi.org/10.1016/j.cancergencyto.2010.07.044
Pajic M; Kersbergen A; Van Diepen F; Pfauth A; Jonkers J; Borst P; Rottenberg S, 2010, 'Tumor-initiating cells are not enriched in cisplatin-surviving BRCA1;p53-deficient mammary tumor cells in vivo', Cell Cycle, 9, pp. 3804 - 3815, http://dx.doi.org/10.4161/cc.9.18.13002
Journal articles | 2010
Rottenberg S; Pajic M; Jonkers J, 2010, 'Studying drug resistance using genetically engineered mouse models for breast cancer.', Methods in molecular biology (Clifton, N.J.), 596, pp. 33 - 45, http://dx.doi.org/10.1007/978-1-60761-416-6_3
Zander SAL; Kersbergen A; Van Der Burg E; De Water N; Van Tellingen O; Gunnarsdottir S; Jaspers JE; Pajic M; Nygren AOH; Jonkers J; Borst P; Rottenberg S, 2010, 'Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan', Cancer Research, 70, pp. 1700 - 1710, http://dx.doi.org/10.1158/0008-5472.CAN-09-3367
Journal articles | 2009
Pajic M; Iyer JK; Kersbergen A; Van Der Burg E; Nygren AOH; Jonkers J; Borst P; Rottenberg S, 2009, 'Moderate increase in Mdr1a/1b expression causes in vivo resistance to doxorubicin in a mouse model for hereditary breast cancer', Cancer Research, 69, pp. 6396 - 6404, http://dx.doi.org/10.1158/0008-5472.CAN-09-0041
Journal articles | 2007
Chung S; Wei A; Connor DE; Webb GC; Molloy TJ; Pajic M; Diwan AD, 2007, 'Nucleus pulposus cellular longevity by telomerase gene therapy', Spine, 32, pp. 1188 - 1196, http://dx.doi.org/10.1097/BRS.0b013e31805471a3
Journal articles | 2007
Rottenberg S; Nygren AOH; Pajic M; Van Leeuwen FWB; Van Der Heijden I; Van Wetering KD; Liu X; De Visser KE; Gilhuijs KG; Van Tellingen O; Schouten JP; Jonkers J; Borst P, 2007, 'Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer', Proceedings of the National Academy of Sciences of the United States of America, 104, pp. 12117 - 12122, http://dx.doi.org/10.1073/pnas.0702955104
Journal articles | 2005
Pajic M; Norris MD; Cohn RJ; Haber M, 2005, 'The role of the multidrug resistance-associated protein 1 gene in neuroblastoma biology and clinical outcome', Cancer Letters, 228, pp. 241 - 246, http://dx.doi.org/10.1016/j.canlet.2005.01.060
Journal articles | 2004
Pajic M; Bebawy M; Hoskins JM; Roufogalis BD; Rivory LP, 2004, 'Effect of short-term morphine exposure on P-glycoprotein expression and activity in cancer cell lines', Oncology Reports, 11, pp. 1091 - 1095, http://dx.doi.org/10.3892/or.11.5.1091
Journal articles | 1987
Ivanovic V; Filipovic V; Pajic M; Santini A, 1987, 'Tertiary dentine formation in dogs' teeth in response to lining materials.', J Dent, 15, pp. 85 - 87, http://dx.doi.org/10.1016/0300-5712(87)90006-6
Working Papers | 2020
Thejer B; Adhikary P; Kaur A; Teakel S; Oosterum AV; Seth I; Pajic M; Hannan K; Pavy M; Poh P; Jazayeri J; Zaw T; Pascovici D; Ludescher M; Pawlak M; Cassano J; Turnbull L; Jazayeri M; James A; Coorey C; Roberts T; Kinder S; Hannan R; Patrick E; Molloy M; J E; Fehm T; Neubauer H; Goldys E; Weston L; CAHILL M, 2020, PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth, http://dx.doi.org10.21203/rs.2.22342/v3
Working Papers | 2019
Thejer B; Adhikary P; Kaur A; Teakel S; Van Oosterum A; Seth I; Pajic M; Hannan K; Pavy M; Poh P; Jazayeri J; Zaw T; Pascovici D; Ludescher M; Pawlak M; Cassano J; Turnbull L; Jazayeri M; James A; Coorey C; Roberts T; Kinder S; Hannan R; Patrick E; Molloy M; New E; Fehm T; Neubauer H; Goldys E; Weston L; Cahill M, 2019, PGRMC1 phosphorylation and cell plasticity 1: glycolysis, mitochondria, tumor growth, Cold Spring Harbor Laboratory, http://dx.doi.org10.1101/737718
Preprints | 2023
Colino-Sanguino Y; Fuente LRDL; Gloss B; Law A; Handler K; Pajic M; Salomon R; Gallego-Ortega D; Valdes-Mora F, 2023, Systematic comparison of high throughput Single-Cell RNA-Seq platforms in complex tissues, , http://dx.doi.org/10.1101/2023.04.04.535585
Preprints | 2022
Kokkinos J; Sharbeen G; Ignacio RMC; Pandzic E; Youkhana J; Boyer C; Haghighi KS; Gunawarman M; Goldstein D; Gebski V; Pajic M; Pitiyarachchi O; Davis ME; Schulstad G; Arkell OSM; Kopecky C; Gonzales-Aloy E; Erkan M; Morton JP; Kavallaris M; Gunning PW; Hardeman EC; Johns A; Gill AJ; Whan RM; Mawson A; McCarroll JA; Phillips PA, 2022, βIII-Tubulin is a Brake on Extrinsic Cell-Death in Pancreatic Cancer, , http://dx.doi.org/10.1101/2022.09.29.510034
Preprints | 2020
Kryza T; Khan T; Lovell S; Harrington BS; Yin J; Porazinski S; Pajic M; Koistinen H; Rantala J; Dreyer T; Magdolen V; Reuning U; He Y; Tate E; Hooper JD, 2020, Substrate-biased activity-based probes identify the urokinase-plasminogen axis as a master regulator of metastatic signaling by orphan membrane receptor CDCP1, , http://dx.doi.org/10.21203/rs.3.rs-92391/v1
Preprints | 2020
Thejer BM; Adhikary PP; Kaur A; Teakel SL; Oosterum AV; Seth I; Pajic M; Hannan KM; Pavy M; Poh P; Jazayeri JA; Zaw T; Pascovici D; Ludescher M; Pawlak M; Cassano JC; Turnbull L; Jazayeri M; James AC; Coorey CP; Roberts TL; Kinder SJ; Hannan RD; Patrick E; Molloy MP; J. E; Fehm TN; Neubauer H; Goldys EM; Weston LA; CAHILL M, 2020, PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth, , http://dx.doi.org/10.21203/rs.2.22342/v1
Preprints | 2020
Thejer BM; Adhikary PP; Kaur A; Teakel SL; Oosterum AV; Seth I; Pajic M; Hannan KM; Pavy M; Poh P; Jazayeri JA; Zaw T; Pascovici D; Ludescher M; Pawlak M; Cassano JC; Turnbull L; Jazayeri M; James AC; Coorey CP; Roberts TL; Kinder SJ; Hannan RD; Patrick E; Molloy MP; J. E; Fehm TN; Neubauer H; Goldys EM; Weston LA; CAHILL M, 2020, PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth, , http://dx.doi.org/10.21203/rs.2.22342/v2
Wang K; Huynh N; Wang X; Pajic M; Parkin A; Man J; Baldwin G; He H; Nikfarjam M, 2018, The PAK Inhibitor PF-3758309 Promotes the Inhibitory Effects of Multiple Chemotherapeutic Reagents on Patient-Derived Pancreatic Cancer Cell Lines, , http://dx.doi.org/10.20944/preprints201809.0322.v1
Conference Abstracts | 2017
Chin VT; Nagrial A; Conway J; Vennin C; Chantrill LA; Chou A; Steinmann A; Gill AJ; Humprhis J; Drury A; Froio D; Morgan A; Biankin A; Timpson P; Pajic M, 2017, 'Effect of Rho/ROCK pathway inhibition on metastasis-free and overall survival in biomarker selected, orthotopic, patient-derived models of pancreatic cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, Vol. 35, presented at 53rd Annual Clinical Science Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Symposium on Old Targets, New Drugs - Her2 and MET, IL, Chicago, 02 June 2017 - 07 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.e15759
Conference Papers | 2016
Chou A; Steinmann A; Froio D; Drury A; Wohl D; Chin V; Nagrial A; Gill A; Pajic M, 2016, 'Combination of CDK4/6 inhibitor PD-0332991 with standard chemotherapy is synergistic in RB high pancreatic cancer', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, pp. S182 - S182, http://dx.doi.org/10.1016/S0959-8049(16)61645-3
Conference Abstracts | 2015
Chin VT; Conway J; Nagrial A; Chantrill LA; Chou A; Steinmann A; Gill A; Pinese M; Wu J; Johns A; Dury A; Biankin A; Timpson P; Pajic M, 2015, 'Targeting the Rho-ROCK pathway to treat pancreatic cancer: The use of unique preclinical models to ascertain the effects on cancer growth and metastasis', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, CA, San Francisco, Vol. 33, presented at Gastrointestinal Cancers Symposium, CA, San Francisco, 15 January 2015 - 17 January 2015, http://dx.doi.org/10.1200/jco.2015.33.3_suppl.312
Chin VT; Nagrial A; Chantrill LA; Sjoquist KM; O'Connor C; Pajic M; Blankin AV; Yip D, 2014, 'Targeted therapies in the treatment of advanced pancreatic adenocarcinoma (PC): A systematic review and meta-analysis of randomized trials', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, presented at 50th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 30 May 2014 - 03 June 2014, http://dx.doi.org/10.1200/jco.2014.32.15_suppl.e15209
Pinho AV; Grimont A; Cowley MJ; Augereau C; Mawson A; Giry-Laterriere M; Van den Steen G; Waddell N; Pajic M; Sempoux C; Wu J; Grimmond SM; Biankin AV; Lemaigre FP; Jacquemin P; Rooman I, 2014, 'SOX9 regulates EGFR/ERBB signaling in pancreatic cancer', Vol. 74, presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-LB-73
Conference Papers | 2013
Chang DK; Pinese M; Scarlett CJ; Pajic M; Colvin EK; Johns AL; Wu J; Cowley MJ; Humphris JL; Chou A; Nguyen NQ; Nagrial AM; Chantrill L; Chin VT; Musgrove EA; Altekruse S; Gill AJ; Kench JG; Biankin AV, 2013, 'A molecular pre-operative prognostic nomogram for resectable pancreatic cancer', in Cancer Research, American Association for Cancer Research, Washington, DC, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-1156
Molloy T; Pajic M; Holzhauser S; Graham P; Millar EKA; Sutherland RL, 2012, 'Identifying Putative MiRNAs Mediators of Radiotherapy Resistance in Breast Cancer', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, SPAIN, Barcelona, pp. S270 - S270, presented at 22nd Biennial Congress of the European-Association-for-Cancer-Research, SPAIN, Barcelona, 07 July 2012 - 10 July 2012, http://dx.doi.org/10.1016/S0959-8049(12)71723-9
Conference Abstracts | 2012
Pajic M; Chang DK; Kassahn KS; Wu J; Cowley M; Waddell N; Johns A; Grimmond SM; Biankin AV, 2012, 'Proffered Paper: Testing Individualised Treatment Strategies in Preclinical Models of Pancreatic Cancer', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, SPAIN, Barcelona, Vol. 48, pp. S22 - S22, presented at 22nd Biennial Congress of the European-Association-for-Cancer-Research, SPAIN, Barcelona, 07 July 2012 - 10 July 2012, http://dx.doi.org/10.1016/S0959-8049(12)70795-5
Conference Papers | 2010
Borst P; Rottenberg S; Jonkers J; Zander S; Pajic M; Jaspers J, 2010, 'Abstract PL6-1: Resistance to targeted therapies in a realistic mouse breast cancer model', in Clinical Cancer Research, American Association for Cancer Research (AACR), presented at Abstracts: AACR International Conference on Translational Cancer Medicine--; Mar 21–24, 2010; Amsterdam, The Netherlands, http://dx.doi.org/10.1158/1078-0432.tcme10-pl6-1
Conference Papers | 2010
Rottenberg S; Pajic M; Kersbergen A; Banishki N; Xu G; Jonkers J; Borst P, 2010, 'Abstract A14: Lack of tumor eradication of chemotherapy-sensitive BRCA1;p53-deficient mouse mammary tumors', in Clinical Cancer Research, American Association for Cancer Research (AACR), pp. A14 - A14, presented at Abstracts: AACR International Conference on Translational Cancer Medicine--; Mar 21-24, 2010; Amsterdam, The Netherlands, http://dx.doi.org/10.1158/1078-0432.tcme10-a14
Murray J; Burkhart CA; Watt F; Pajic M; Flemming C; Smith J; Gudkov AV; Haber M; Norris MD, 2006, 'Sensitisation of neuroblastorna tumours to chemotherapy by use of a novel class of MRP1 small molecule inhibitor', in EJC SUPPLEMENTS, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 4, pp. 54 - 54, http://dx.doi.org/10.1016/S1359-6349(06)70175-6