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Professor Marina Pajic

Conjoint Professor
Medicine & Health
School of Clinical Medicine
Phone
02 9355 5834
  • Journal articles | 2025
    Chambers CR; Watakul S; Schofield P; Howell AE; Zhu J; Tran AMH; Kuepper N; Reed DA; Murphy KJ; Channon LM; Pereira BA; Tyma VM; Lee V; Trpceski M; Henry J; Melenec P; Abdulkhalek L; Nobis M; Metcalf XL; Ritchie S; Cadell A; Stoehr J; Magenau A; Chacon-Fajardo D; Chitty JL; O’Connell S; Zaratzian A; Tayao M; Silva AD; Lyons RJ; Goldstein LD; Dale A; Rookyard A; Connolly A; Crossett B; Tran YTH; Kaltzis P; Vennin C; Dinevska M; Croucher DR; Samra J; Mittal A; Weatheritt RJ; Philp A; Monte-Nieto GD; Zhang L; Enriquez RF; Cox TR; Shi YCC; Pinese M; Waddell N; Sim HW; Chtanova T; Wang Y; Joshua AM; Chantrill L; Jeffry Evans TR; Gill AJ; Morton JP; Pajic M; Christ D; Herzog H; Timpson P; Herrmann D, 2025, 'Targeting the NPY/NPY1R signaling axis in mutant p53–dependent pancreatic cancer impairs metastasis', Science Advances, 11, http://dx.doi.org/10.1126/sciadv.adq4416
    Journal articles | 2025
    Ephraums J; Youkhana J; Raina AS; Schulstad G; Croft K; Mawson A; Kokkinos J; Gonzales-Aloy E; Ignacio RMC; McCarroll JA; Boyer C; Goldstein D; Pajic M; Haghighi KS; Johns A; Gill AJ; Erkan M; Initiative (APGI) APCG; Phillips PA; Sharbeen G, 2025, 'MYH knockdown in pancreatic cancer cells creates an exploitable DNA repair vulnerability', Neoplasia (United States), 61, http://dx.doi.org/10.1016/j.neo.2025.101138
    Journal articles | 2025
    Malhotra P; Fyfe J; Emmanouilidi A; Casari I; Mellett NA; Huynh K; Pajic M; Greening DW; Meikle PJ; Falasca M, 2025, 'Oncogenic small extracellular vesicles enriched in sphingosine-1-phosphate play a crucial role in pancreatic cancer progression', Cellular Signalling, 132, http://dx.doi.org/10.1016/j.cellsig.2025.111775
    Journal articles | 2025
    Panda A; Ragunath K; Pajic M; Greening DW; Falasca M, 2025, 'Oncogenic proteome of pancreatic cancer extracellular vesicles: sodium/myo-inositol cotransporter as a potential marker.', Signal Transduct Target Ther, 10, pp. 148, http://dx.doi.org/10.1038/s41392-025-02232-9
    Journal articles | 2024
    Colino-Sanguino Y; Rodriguez de la Fuente L; Gloss B; Law AMK; Handler K; Pajic M; Salomon R; Gallego-Ortega D; Valdes-Mora F, 2024, 'Performance comparison of high throughput single-cell RNA-Seq platforms in complex tissues', Heliyon, 10, http://dx.doi.org/10.1016/j.heliyon.2024.e37185
    Journal articles | 2024
    Istadi A; Porazinski S; Pajic M, 2024, 'Cancer variant modeling in vivo', Nature Biotechnology, 42, pp. 383 - 385, http://dx.doi.org/10.1038/s41587-023-02080-4
    Journal articles | 2024
    McGahan W; Gough M; Liu C; Hoyte S; Gill AJ; Cavallucci D; Cooper C; Butler N; Yeung S; Kryza T; Gulhane B; Latter MJ; Waddell N; Samra JS; Simpson F; Pajic M; Thomas PA; O'Rourke T; Hooper JD, 2024, 'Fibroblast Activation Protein Is Overexpressed on Both Stromal and Epithelial Cells Before Pancreatic Ductal Adenocarcinoma: Implications for Early Diagnosis on 68Ga-FAPI-PET/CT', Gastroenterology, 167, pp. 1217 - 1220, http://dx.doi.org/10.1053/j.gastro.2024.06.033
    Journal articles | 2024
    Pajic M; McLean B; Fajardo DC; Porazinski S; Upton DH; Schuhmacher D; Istadi A; Cox T; Timpson P; Wilcock DJ; Anderson KJ; Mason H; Guisot NE; Jones CD; Phillips C; Armer R, 2024, 'Abstract 720: Combining zelasudil, a small molecule ROCK2 inhibitor, with chemotherapy or immunotherapy improves response in preclinical models of pancreatic cancer', Cancer Research, 84, pp. 720 - 720, http://dx.doi.org/10.1158/1538-7445.am2024-720
    Journal articles | 2024
    Pereira BA; Ritchie S; Chambers CR; Gordon KA; Magenau A; Murphy KJ; Nobis M; Tyma VM; Liew YF; Lucas MC; Naeini MM; Barkauskas DS; Chacon-Fajardo D; Howell AE; Parker AL; Warren SC; Reed DA; Lee V; Metcalf XL; Lee YK; O'Regan LP; Zhu J; Trpceski M; Fontaine ARM; Stoehr J; Rouet R; Lin X; Chitty JL; Porazinski S; Wu SZ; Filipe EC; Cadell AL; Holliday H; Yang J; Papanicolaou M; Lyons RJ; Zaratzian A; Tayao M; Da Silva A; Vennin C; Yin J; Dew AB; McMillan PJ; Goldstein LD; Deveson IW; Croucher DR; Samuel MS; Sim HW; Batten M; Chantrill L; Grimmond SM; Gill AJ; Samra J; Jeffry Evans TR; Sasaki T; Phan TG; Swarbrick A; Sansom OJ; Morton JP; Pajic M; Parker BL; Herrmann D; Cox TR; Timpson P, 2024, 'Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response', Science Advances, 10, http://dx.doi.org/10.1126/sciadv.adl1197
    Journal articles | 2024
    Pitiyarachchi O; Lin FP; Spooner A; Sharbeen G; Barker HP; Thornton K; Collignon E; Ballinger ML; Thomas DM; Magenau A; Porazinski S; Raina A; Sjoquist KM; Chantrill LA; Gebski V; Sowmya A; Timpson P; Pajic M; Goldstein D; Phillips PA, 2024, '1513P Impact of symptom and functional burden on survival in pancreatic ductal adenocarcinoma (PDAC)', Annals of Oncology, 35, pp. S925 - S925, http://dx.doi.org/10.1016/j.annonc.2024.08.1576
    Journal articles | 2024
    Tyma V; Liew Y-F; Tran A; Howell A; Ritchie S; Pancreatic Cancer Matrix Atlas AA; Genome Initiative AP; Cox T; Pajic M; Herrmann D; Pereira B; Timpson P; Gordon K, 2024, 'Abstract A067: Identifying and targeting FOLFIRINOX resistance mechanisms to improve outcomes in pancreatic cancer', Cancer Research, 84, pp. A067 - A067, http://dx.doi.org/10.1158/1538-7445.pancreatic24-a067
    Journal articles | 2024
    Upton D; Fajardo DC; Omari S; Porazinski S; McLean B; Schuhmacher D; Istadi A; Kothari V; Finkelstein D; Machajewski T; Rock F; Turner S; Pajic M, 2024, 'Selective targeting of integrins αVβ8 and αVβ1 within the dynamic ecosystem of pancreatic cancer to improve the overall anti-tumor response', CANCER RESEARCH, 84, http://dx.doi.org/10.1158/1538-7445.AM2024-6575
    Journal articles | 2023
    Aaltonen LA; Abascal F; Abeshouse A; Aburatani H; Adams DJ; Agrawal N; Ahn KS; Ahn SM; Aikata H; Akbani R; Akdemir KC; Al-Ahmadie H; Al-Sedairy ST; Al-Shahrour F; Alawi M; Albert M; Aldape K; Alexandrov LB; Ally A; Alsop K; Alvarez EG; Amary F; Amin SB; Aminou B; Ammerpohl O; Anderson MJ; Ang Y; Antonello D; Anur P; Aparicio S; Appelbaum EL; Arai Y; Aretz A; Arihiro K; Ariizumi SI; Armenia J; Arnould L; Asa S; Assenov Y; Atwal G; Aukema S; Auman JT; Aure MRR; Awadalla P; Aymerich M; Bader GD; Baez-Ortega A; Bailey MH; Bailey PJ; Balasundaram M; Balu S; Bandopadhayay P; Banks RE; Barbi S; Barbour AP; Barenboim J; Barnholtz-Sloan J; Barr H; Barrera E; Bartlett J; Bartolome J; Bassi C; Bathe OF; Baumhoer D; Bavi P; Baylin SB; Bazant W; Beardsmore D; Beck TA; Behjati S; Behren A; Niu B; Bell C; Beltran S; Benz C; Berchuck A; Bergmann AK; Bergstrom EN; Berman BP; Berney DM; Bernhart SH; Beroukhim R; Berrios M; Bersani S; Bertl J; Betancourt M; Bhandari V; Bhosle SG; Biankin AV; Bieg M; Bigner D; Binder H; Birney E; Birrer M; Biswas NK; Bjerkehagen B; Bodenheimer T; Boice L; Bonizzato G; De Bono JS, 2023, 'Author Correction: Pan-cancer analysis of whole genomes (Nature, (2020), 578, 7793, (82-93), 10.1038/s41586-020-1969-6)', Nature, 614, pp. E39, http://dx.doi.org/10.1038/s41586-022-05598-w
    Journal articles | 2023
    Alexandrov LB; Kim J; Haradhvala NJ; Huang MN; Tian Ng AW; Wu Y; Boot A; Covington KR; Gordenin DA; Bergstrom EN; Islam SMA; Lopez-Bigas N; Klimczak LJ; McPherson JR; Morganella S; Sabarinathan R; Wheeler DA; Mustonen V; Boutros P; Chan K; Fujimoto A; Getz G; Kazanov M; Lawrence M; Martincorena I; Nakagawa H; Polak P; Prokopec S; Roberts SA; Rozen SG; Saini N; Shibata T; Shiraishi Y; Stratton MR; Teh BT; Vázquez-García I; Yousif F; Yu W; Aaltonen LA; Abascal F; Abeshouse A; Aburatani H; Adams DJ; Agrawal N; Ahn KS; Ahn SM; Aikata H; Akbani R; Akdemir KC; Al-Ahmadie H; Al-Sedairy ST; Al-Shahrour F; Alawi M; Albert M; Aldape K; Ally A; Alsop K; Alvarez EG; Amary F; Amin SB; Aminou B; Ammerpohl O; Anderson MJ; Ang Y; Antonello D; Anur P; Aparicio S; Appelbaum EL; Arai Y; Aretz A; Arihiro K; Ariizumi SI; Armenia J; Arnould L; Asa S; Assenov Y; Atwal G; Aukema S; Auman JT; Aure MRR, 2023, 'Author Correction: The repertoire of mutational signatures in human cancer (Nature, (2020), 578, 7793, (94-101), 10.1038/s41586-020-1943-3)', Nature, 614, pp. E41, http://dx.doi.org/10.1038/s41586-022-05600-5
    Journal articles | 2023
    Calabrese C; Davidson NR; Demircioğlu D; Fonseca NA; He Y; Kahles A; Lehmann KV; Liu F; Shiraishi Y; Soulette CM; Urban L; Greger L; Li S; Liu D; Perry MD; Xiang Q; Zhang F; Zhang J; Bailey P; Erkek S; Hoadley KA; Hou Y; Huska MR; Kilpinen H; Korbel JO; Marin MG; Markowski J; Nandi T; Pan-Hammarström Q; Pedamallu CS; Siebert R; Stark SG; Su H; Tan P; Waszak SM; Yung C; Zhu S; Awadalla P; Creighton CJ; Meyerson M; Ouellette BFF; Wu K; Yang H; Perry MD; Amin SB; Bailey P; Chateigner A; Cortés-Ciriano I; Craft B; Frenkel-Morgenstern M; Goldman M; Khurana E; Lamaze FC; Li C; Li X; Li X; Liu X; Nielsen MM; Ojesina AI; Park PJ; Pedersen JS, 2023, 'Author Correction: Genomic basis for RNA alterations in cancer (Nature, (2020), 578, 7793, (129-136), 10.1038/s41586-020-1970-0)', Nature, 614, pp. E37, http://dx.doi.org/10.1038/s41586-022-05596-y
    Journal articles | 2023
    Chitty JL; Yam M; Perryman L; Parker AL; Skhinas JN; Setargew YFI; Mok ETY; Tran E; Grant RD; Latham SL; Pereira BA; Ritchie SC; Murphy KJ; Trpceski M; Findlay AD; Melenec P; Filipe EC; Nadalini A; Velayuthar S; Major G; Wyllie K; Papanicolaou M; Ratnaseelan S; Phillips PA; Sharbeen G; Youkhana J; Russo A; Blackwell A; Hastings JF; Lucas MC; Chambers CR; Reed DA; Stoehr J; Vennin C; Pidsley R; Zaratzian A; Da Silva AM; Tayao M; Charlton B; Herrmann D; Nobis M; Clark SJ; Biankin AV; Johns AL; Croucher DR; Nagrial A; Gill AJ; Grimmond SM; Chantrill LA; Chou A; Dwarte T; Metcalf XL; Jeong G; Kenyon L; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Hofmann O; Samra JS; Pavlakis N; Arena J; High HA; Asghari R; Merrett ND; Das A; Cosman PH; Ismail K; Stoita A; Williams D; Spigellman A; McLeo D; Kirk J; Kench JG; Grimison P; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forrest C; Ballal M; Fletcher D; Beilin M; Feeney K; Epari K; Mukhedkar S; Zeps N; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J, 2023, 'A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer', Nature Cancer, 4, pp. 1326 - 1344, http://dx.doi.org/10.1038/s43018-023-00614-y
    Journal articles | 2023
    Gerstung M; Jolly C; Leshchiner I; Dentro SC; Gonzalez S; Rosebrock D; Mitchell TJ; Rubanova Y; Anur P; Yu K; Tarabichi M; Deshwar A; Wintersinger J; Kleinheinz K; Vázquez-García I; Haase K; Jerman L; Sengupta S; Macintyre G; Malikic S; Donmez N; Livitz DG; Cmero M; Demeulemeester J; Schumacher S; Fan Y; Yao X; Lee J; Schlesner M; Boutros PC; Bowtell DDL; Zhu H; Getz G; Imielinski M; Beroukhim R; Sahinalp SC; Ji Y; Peifer M; Markowetz F; Mustonen V; Yuan K; Wang W; Morris QD; Adams DJ; Campbell PJ; Cao S; Christie EL; Cun Y; Dawson KJ; Drews RM; Fittall M; Garsed DW; Ha G; Lee-Six H; Martincorena I; Oesper L; Peto M; Raphael BJ; Salcedo A; Shi R; Shin SJ; Spiro O; Stein LD; Vembu S; Wheeler DA, 2023, 'Author Correction: The evolutionary history of 2,658 cancers (Nature, (2020), 578, 7793, (122-128), 10.1038/s41586-019-1907-7)', Nature, 614, pp. E42, http://dx.doi.org/10.1038/s41586-022-05601-4
    Journal articles | 2023
    Li Y; Roberts ND; Wala JA; Shapira O; Schumacher SE; Kumar K; Khurana E; Waszak S; Korbel JO; Haber JE; Imielinski M; Akdemir KC; Alvarez EG; Baez-Ortega A; Beroukhim R; Boutros PC; Bowtell DDL; Brors B; Burns KH; Campbell PJ; Chan K; Chen K; Cortés-Ciriano I; Dueso-Barroso A; Dunford AJ; Edwards PA; Estivill X; Etemadmoghadam D; Feuerbach L; Fink JL; Frenkel-Morgenstern M; Garsed DW; Gerstein M; Gordenin DA; Haan D; Hess JM; Hutter B; Jones DTW; Ju YS; Kazanov MD; Klimczak LJ; Koh Y; Lee EA; Lee JJK; Lynch AG; Macintyre G; Markowetz F; Martincorena I; Martinez-Fundichely A; Meyerson M; Miyano S; Nakagawa H; Navarro FCP; Ossowski S; Park PJ; Pearson JV; Puiggròs M; Rippe K; Roberts SA; Rodriguez-Martin B; Scully R; Shackleton M; Sidiropoulos N; Sieverling L; Stewart C; Torrents D; Tubio JMC; Villasante I; Waddell N; Weischenfeldt J; Yang L; Yao X; Yoon SS; Zamora J; Zhang CZ; Aaltonen LA; Abascal F; Abeshouse A; Aburatani H; Adams DJ; Agrawal N; Ahn KS; Ahn SM; Aikata H; Akbani R; Akdemir KC; Al-Ahmadie H; Al-Sedairy ST; Al-Shahrour F; Alawi M; Albert M, 2023, 'Author Correction: Patterns of somatic structural variation in human cancer genomes (Nature, (2020), 578, 7793, (112-121), 10.1038/s41586-019-1913-9)', Nature, 614, pp. E38, http://dx.doi.org/10.1038/s41586-022-05597-x
    Journal articles | 2023
    Rheinbay E; Nielsen MM; Abascal F; Wala JA; Shapira O; Tiao G; Hornshøj H; Hess JM; Juul RI; Lin Z; Feuerbach L; Sabarinathan R; Madsen T; Kim J; Mularoni L; Shuai S; Lanzós A; Herrmann C; Maruvka YE; Shen C; Amin SB; Bandopadhayay P; Bertl J; Boroevich KA; Busanovich J; Carlevaro-Fita J; Chakravarty D; Chan CWY; Craft D; Dhingra P; Diamanti K; Fonseca NA; Gonzalez-Perez A; Guo Q; Hamilton MP; Haradhvala NJ; Hong C; Isaev K; Johnson TA; Juul M; Kahles A; Kahraman A; Kim Y; Komorowski J; Kumar K; Kumar S; Lee D; Lehmann KV; Li Y; Liu EM; Lochovsky L; Park K; Pich O; Roberts ND; Saksena G; Schumacher SE; Sidiropoulos N; Sieverling L; Sinnott-Armstrong N; Stewart C; Tamborero D; Umer HM; Uusküla-Reimand L; Wadelius C; Wadi L; Yao X; Zhang CZ; Zhang J; Haber JE; Hobolth A; Imielinski M; Kellis M; Lawrence MS; von Mering C; Nakagawa H; Raphael BJ; Rubin MA; Sander C; Stein LD; Stuart JM; Tsunoda T; Wheeler DA; Johnson R; Reimand J; Gerstein M; Khurana E; Campbell PJ; López-Bigas N; Bader GD; Barenboim J; Beroukhim R; Brunak S, 2023, 'Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes (Nature, (2020), 578, 7793, (102-111), 10.1038/s41586-020-1965-x)', Nature, 614, pp. E40, http://dx.doi.org/10.1038/s41586-022-05599-9
    Journal articles | 2023
    Rodriguez-Martin B; Alvarez EG; Baez-Ortega A; Zamora J; Supek F; Demeulemeester J; Santamarina M; Temes J; Garcia-Souto D; Detering H; Li Y; Rodriguez-Castro J; Dueso-Barroso A; Bruzos AL; Dentro SC; Blanco MG; Contino G; Ardeljan D; Tojo M; Roberts ND; Zumalave S; Edwards PA; Weischenfeldt J; Puiggròs M; Chong Z; Chen K; Lee EA; Wala JA; Raine KM; Butler A; Waszak SM; Navarro FCP; Schumacher SE; Monlong J; Maura F; Bolli N; Gerstein M; Park PJ; Wedge DC; Beroukhim R; Torrents D; Korbel JO; Martincorena I; Fitzgerald RC; Van Loo P; Kazazian HH; Burns KH; Akdemir KC; Boutros PC; Bowtell DDL; Brors B; Campbell PJ; Chan K; Chen K; Cortés-Ciriano I; Dunford AJ; Estivill X; Etemadmoghadam D; Feuerbach L; Fink JL; Frenkel-Morgenstern M; Garsed DW; Gordenin DA; Haan D; Haber JE; Hess JM; Hutter B; Imielinski M; Jones DTW; Ju YS; Kazanov MD; Klimczak LJ; Koh Y; Kumar K; Lee JJK; Lynch AG; Macintyre G; Markowetz F; Martinez-Fundichely A; Meyerson M; Miyano S; Nakagawa H; Ossowski S; Pearson JV; Rippe K; Roberts SA, 2023, 'Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition (Nature Genetics, (2020), 52, 3, (306-319), 10.1038/s41588-019-0562-0)', Nature Genetics, 55, pp. 1080, http://dx.doi.org/10.1038/s41588-023-01319-9
    Journal articles | 2023
    Yakneen S; Waszak SM; Aminou B; Bartolome J; Boroevich KA; Boyce R; Brooks AN; Buchanan A; Buchhalter I; Butler AP; Byrne NJ; Cafferkey A; Campbell PJ; Chen Z; Cho S; Choi W; Clapham P; Davis-Dusenbery BN; De La Vega FM; Demeulemeester J; Dow MT; Dursi LJ; Eils J; Eils R; Ellrott K; Farcas C; Favero F; Fayzullaev N; Ferretti V; Flicek P; Fonseca NA; Gelpi JL; Getz G; Gibson B; Grossman RL; Harismendy O; Heath AP; Heinold MC; Hess JM; Hofmann O; Hong JH; Hudson TJ; Hutter B; Hutter CM; Hübschmann D; Imoto S; Ivkovic S; Jeon SH; Jiao W; Jung J; Kabbe R; Kahles A; Kerssemakers JNA; Kim HL; Kim H; Kim J; Kim Y; Kleinheinz K; Koscher M; Koures A; Kovacevic M; Lawerenz C; Leshchiner I; Liu J; Livitz D; Mihaiescu GL; Mijalkovic S; Mijalkovic Lazic A; Miyano S; Miyoshi N; Nahal-Bose HK; Nakagawa H; Nastic M; Newhouse SJ; Nicholson J; O’Connor BD; Ocana D; Ohi K; Ohno-Machado L; Omberg L; Ouellette BFF; Paramasivam N; Perry MD; Pihl TD; Prinz M; Puiggròs M; Radovic P; Raine KM; Rheinbay E; Rosenberg M; Royo R; Rätsch G; Saksena G; Schlesner M; Shorser SI; Short C; Sofia HJ; Spring J; Stein LD; Struck AJ, 2023, 'Author Correction: Butler enables rapid cloud-based analysis of thousands of human genomes (Nature Biotechnology, (2020), 38, 3, (288-292), 10.1038/s41587-019-0360-3)', Nature Biotechnology, 41, pp. 577, http://dx.doi.org/10.1038/s41587-022-01554-1
    Journal articles | 2022
    Dreyer SB; Upstill-Goddard R; Legrini A; Biankin AV; Allison S; Beraldi D; Cameron E; Chang DK; Cooke SL; Cunningham R; Grimwood P; Kelly S; Marshall J; McDade B; Musgrove EA; Ramsay D; Evers L; Rebus S; Rahib L; Serrels B; Jamieson NB; McKay CJ; Westwood P; Williams N; Duthie F; Shen W; Pea A; Johns AL; Gill AJ; Chantrill LA; Timpson P; Chou A; Pajic M; Dwarte T; Herrmann D; Vennin C; Cox TR; Pereira B; Ritchiee S; Reed DA; Chambers CR; Metcalf X; Nobis M; Jeong G; Kenyon L; Lyons RJ; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Grimmond SM; Hofmann O; Samra JS; Pavlakis N; Arena J; High HA; Asghari R; Merrett ND; Das A; Cosman PH; Ismail K; Stoita A; Williams D; Spigellman A; McLeod D; Kirk J; Kench JG; Grimison P; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forrest C; Ballal M; Fletcher D; Beilin M; Feeney K; Epari K; Mukhedkar S; Zeps N; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J; Brooke-Smith ME; Papangelis V; Clouston AD; Barbour AP; O'Rourke TJ; Fawcett JW, 2022, 'Genomic and Molecular Analyses Identify Molecular Subtypes of Pancreatic Cancer Recurrence', Gastroenterology, 162, pp. 320 - 324.e4, http://dx.doi.org/10.1053/j.gastro.2021.09.022
    Journal articles | 2022
    Khan T; Lyons NJ; Gough M; Kwah KKX; Cuda TJ; Snell CE; Tse BW; Sokolowski KA; Pearce LA; Adams TE; Rose SE; Puttick S; Pajic M; Adams MN; He Y; Hooper JD; Kryza T, 2022, 'CUB Domain-Containing Protein 1 (CDCP1) is a rational target for the development of imaging tracers and antibody-drug conjugates for cancer detection and therapy', Theranostics, 12, pp. 6915 - 6930, http://dx.doi.org/10.7150/thno.78171
    Journal articles | 2022
    McLean B; Istadi A; Clack T; Vankan M; Schramek D; Neely GG; Pajic M, 2022, 'A CRISPR Path to Finding Vulnerabilities and Solving Drug Resistance: Targeting the Diverse Cancer Landscape and Its Ecosystem.', Adv Genet (Hoboken), 3, pp. 2200014, http://dx.doi.org/10.1002/ggn2.202200014
    Journal articles | 2022
    Poh AR; O'Brien M; Chisanga D; He H; Baloyan D; Traichel J; Dijkstra C; Chopin M; Nutt S; Whitehead L; Boon L; Parkin A; Lowell C; Pajic M; Shi W; Nikfarjam M; Ernst M, 2022, 'Inhibition of HCK in myeloid cells restricts pancreatic tumor growth and metastasis', Cell Reports, 41, http://dx.doi.org/10.1016/j.celrep.2022.111479
    Journal articles | 2021
    Dreyer SB; Upstill-Goddard R; Paulus-Hock V; Paris C; Lampraki EM; Dray E; Serrels B; Caligiuri G; Rebus S; Plenker D; Galluzzo Z; Brunton H; Cunningham R; Tesson M; Nourse C; Bailey UM; Jones MD; Moran-Jones K; Wright DW; Duthie F; Oien K; Evers L; McKay CJ; McGregor GA; Gulati A; Brough R; Bajrami I; Pettitt S; Dziubinski ML; Candido J; Balkwill F; Barry ST; Grützmann R; Rahib L; Allison S; Bailey PJ; Biankin AV; Beraldi D; Cameron E; Chang DK; Cooke SL; Grimwood P; Kelly S; Marshall J; Martin S; McDade B; McElroy D; Musgrove EA; Ramsay D; Wright D; Hair J; Jamieson NB; Westwood P; Williams N; Johns AL; Mawson A; Scarlett CJ; Brancato MAL; Rowe SJ; Simpson SH; Martyn-Smith M; Thomas MT; Chantrill LA; Chin VT; Chou A; Cowley MJ; Humphris JL; Mead RS; Nagrial AM; Pajic M; Pettit J; Pinese M; Rooman I; Wu J; Tao J; DiPietro R; Watson C; Steinmann A; Lee HC; Wong R; Pinho AV; Giry-Laterriere M; Daly RJ; Sutherland RL; Grimmond SM; Waddell N; Kassahn KS; Miller DK; Wilson PJ; Patch AM; Song S; Harliwong I; Idrisoglu S; Nourbakhsh E; Manning S; Wani S; Gongora M; Anderson M; Holmes O; Leonard C; Biankin A; Toon CCW; Pavey D; Merrett N; asghari R; Chang D; Pereira B, 2021, 'Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer', Gastroenterology, 160, pp. 362 - 377.e13, http://dx.doi.org/10.1053/j.gastro.2020.09.043
    Journal articles | 2021
    Geleta B; Park KC; Jansson PJ; Sahni S; Maleki S; Xu Z; Murakami T; Pajic M; Apte MV; Richardson DR; Kovacevic Z, 2021, 'Breaking the cycle: Targeting of NDRG1 to inhibit bi-directional oncogenic cross-talk between pancreatic cancer and stroma', FASEB Journal, 35, http://dx.doi.org/10.1096/fj.202002279R
    Journal articles | 2021
    Kryza T; Khan T; Lovell S; Harrington BS; Yin J; Porazinski S; Pajic M; Koistinen H; Rantala JK; Dreyer T; Magdolen V; Reuning U; He Y; Tate EW; Hooper JD, 2021, 'Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1', Nature Chemical Biology, 17, pp. 776 - 783, http://dx.doi.org/10.1038/s41589-021-00783-w
    Journal articles | 2021
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    Chou A; Waddell N; Cowley MJ; Gill AJ; Chang DK; Patch AM; Nones K; Wu J; Pinese M; Johns AL; Miller DK; Kassahn KS; Nagrial AM; Wasan H; Goldstein D; Toon CW; Chin V; Chantrill L; Humphris J; Mead RS; Rooman I; Samra JS; Pajic M; Musgrove EA; Pearson JV; Morey AL; Grimmond SM; Biankin AV, 2013, 'Clinical and molecular characterization of HER2 amplified-pancreatic cancer', Genome Medicine, 5, pp. 78, http://dx.doi.org/10.1186/gm482
    Journal articles | 2013
    Kassahn KS; Holmes O; Nones K; Patch AM; Miller DK; Christ AN; Harliwong I; Bruxner TJ; Xu Q; Anderson M; Wood S; Leonard C; Taylor D; Newell F; Song S; Idrisoglu S; Nourse C; Nourbakhsh E; Manning S; Wani S; Steptoe A; Pajic M; Cowley MJ; Pinese M; Chang DK; Gill AJ; Johns AL; Wu J; Wilson PJ; Fink L; Biankin AV; Waddell N; Grimmond SM; Pearson JV, 2013, 'Somatic point mutation calling in low cellularity tumors', PLoS ONE, 8, http://dx.doi.org/10.1371/journal.pone.0074380
    Journal articles | 2013
    Kemp MW; Molloy TJ; Pajic M; Chapman E, 2013, 'Peer relationships and the biomedical doctorate: A key component of the contemporary learning environment', Journal of Higher Education Policy and Management, 35, pp. 370 - 385, http://dx.doi.org/10.1080/1360080X.2013.812055
    Journal articles | 2013
    Kemp MW; Pajic M; Molloy TJ; Chapman E, 2013, 'Perceived assessment requirements in the contemporary biomedical doctorate: A case-study from a research intensive australian university', International Journal of Doctoral Studies, 8, pp. 105 - 120, http://dx.doi.org/10.28945/1893
    Journal articles | 2012
    Biankin AV; Waddell NJ; Kassahn KS; Gingras M-C; Muthuswamy L; Johns AL; Miller DK; Wilson PJ; Patchett A-M; Wu J; Chang DK; Cowley MJ; Gardiner BB; Song S; Harliwong I; Idrisoglu S; Nourse C; Nourbakhsh E; Manning S; Wani S; Gongora MM; Pajic M; Scarlett CJ; Gill AJ; Pinho AV; Rooman I; Anderson ML; Holmes O; Leonard C; Taylor DF; Wood SA; Xu Q; Nones K; Fink JL; Christ A; Bruxner T; Cloonan N; Kolle G; Newell F; Pinese M; Mead RS; Humphris J; Kaplan W; Jones M; Colvin EK; Nagrial AM; Humphreys ES; Chou A; Chin VT; Chantrill LA; Mawson A; Samra JS; Kench JG; Lovell JA; Daly RJ; Merrett ND; Toon C; Epari K; Nguyen NQ; Barbour A; Zeps N; Kakkar N; Zhao F; Wu YQ; Wang MJ; Muzny DM; Fisher WE; Brunicardi FC; Hodges SE; Reid JG; Drummond J; Chang K; Han Y; Lewis LR; Dinh H; Buhay CJ; Beck T; Timms L; Sam M; Begley K; Brown A; Pai D; Panchal A; Buchner N; De Borja R; Denroche RE; Yung CK; Serra S; Onetto N; Mukhopadhyay D; Tsao M; Shaw PA; Petersen G; Gallinger S; Hruban R; Maitra A; Iacobuzio-donahue CA; Schulick RD; Wolfgang ; Morgan RA; Lawlor RT; Capelli P; Corbo V; Scardoni M; Tortora G; Tempero MA; Mann KM; Jenkins NA; Perez-Mancera PA; Adams DJ; Largaespada DA; Wessels LFA; Rust AG; Stein LD; Tuveson DA; Copeland NG; Musgrove EA; Scarpa A; Eshleman JR; Hudson TJ; Sutherland RL; Wheeler DA; Pearson JV; McPherson JD; Gibbs RA; Grimmond SM, 2012, 'Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes', Nature, 491, pp. 399 - 405, http://dx.doi.org/10.1038/nature11547
    Journal articles | 2012
    Harliwong I; Gudkov AV; De Ridder J; Burkhart CA; Knosel T; Rummele P; Pajic M; Sartorelli AC; van der Weyden L, 2012, 'Impact of intertumoral heterogeneity on predicting chemotheraphy response of BRCA1-deficient mammary tumors', Cancer Research, 72, pp. 2350 - 2361, http://dx.doi.org/10.1158/0008-5472.CAN-11-4201
    Journal articles | 2012
    Perez-Mancera P; Rust AG; van der Weyden L; Kristiansen GO; Kristiansen GO; Li A; Sarver AL; Silverstein KAT; Grutzmann R; Aust DE; Rummele P; Knosel T; Herd C; Stemple D; Kettleborough R; Brosnan JA; Li A; Richard GM; Knight S; Yu J; Stegeman S; Collier LS; Ten Hoeve JJ; De Ridder J; Klein A; Goggins M; Hruban R; Chang D; Biankin AV; Pinese M; Grimmond S; Wessels L; Wood S; Iacobuzio-donahue CA; Pilarsky CP; Largaespada DA; Adams DJ; Tuveson DA; Rooman I; Pavey D; Cosman P; Nagrial A; Merrett N; asghari R; Cowley M; Daly R; Musgrove E; Pajic M; Wu J; Chang D; Chantrill L; Sutherland R; Gill A; Mawson A; Chou A; Kaplan W; Toon CCW; Johns A, 2012, 'The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma', Nature, 486, pp. 266 - 270, http://dx.doi.org/10.1038/nature11114
    Journal articles | 2012
    Song S; Nones K; Miller DK; Harliwong I; Pinese M; Kassahn KS; Pajic M; Gill A; Johns A; Anderson ML; Holmes O; Leonard C; Taylor DF; Wood SA; Xu Q; Newell FS; Cowley MJ; Wu J; Wilson PJ; Fink L; Biankin AV; Waddell NJ; Grimmond S; Pearson JV, 2012, 'qpure: A tool to estimate tumor cellularity from genome-wide single-nucleotide polymorphism profiles', PLoS ONE, 7, pp. e45835, http://dx.doi.org/10.1371/journal.pone.0045835
    Journal articles | 2011
    Chang DK; Colvin EK; Scarlett CJ; Pajic M; Pinese M; Gill AJ; Musgrove EA; Sutherland R; Kench J; Biankin AV; New South Wales Pancreatic Cancer Network , 2011, 'A molecular prognostic nomogram for resectable pancreatic cancer.', J Clin Oncol, 29, pp. 154, http://www.ncbi.nlm.nih.gov/pubmed/27985628
    Journal articles | 2011
    Chang DK; Colvin EK; Scarlett CJ; Pajic M; Pinese M; Gill AJ; Musgrove EA; Sutherland R; Kench J; Biankin AV, 2011, 'A molecular prognostic nomogram for resectable pancreatic cancer', JOURNAL OF CLINICAL ONCOLOGY, 29, http://dx.doi.org/10.1200/jco.2011.29.4_suppl.154
    Journal articles | 2011
    Chang DK; Johns A; Scarlett CJ; Pajic M; Chou A; Toon C; Samra JS; Sutherland R; Gill AJ; Biankin AV; New South Wales Pancreatic Cancer Network , 2011, 'Molecular pathologic phenotypes and outcome in adenocarcinoma of the ampulla of Vater.', J Clin Oncol, 29, pp. 196, http://www.ncbi.nlm.nih.gov/pubmed/27985359
    Journal articles | 2011
    Chang DK; Johns A; Scarlett CJ; Pajic M; Chou A; Toon C; Samra JS; Sutherland R; Gill AJ; Biankin AV, 2011, 'Molecular pathologic phenotypes and outcome in adenocarcinoma of the ampulla of Vater', JOURNAL OF CLINICAL ONCOLOGY, 29, http://dx.doi.org/10.1200/jco.2011.29.4_suppl.196
    Journal articles | 2010
    Borst P; Rottenberg S; Jonkers J; Zander S; Pajic M; Jaspers J, 2010, 'The contribution of ABC transporters to drug resistance in a realistic mouse mammary tumor model', Cancer Genetics and Cytogenetics, 203, pp. 64 - 64, http://dx.doi.org/10.1016/j.cancergencyto.2010.07.044
    Journal articles | 2010
    Chang D; Johns A; Scarlett C; Pajic M; Chou A; Jones M; Samra J; Henshall S; Musgrove E; Sutherland R; Gill A; Biankin A, 2010, 'Histology and Molecular Pathology Define Clinically Relevant Phenotypes in Carcinoma of the Ampulla of Vater', PANCREAS, 39, pp. 1313 - 1314, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000282946600067&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2010
    Pajic M; Kersbergen A; Van Diepen F; Pfauth A; Jonkers J; Borst P; Rottenberg S, 2010, 'Tumor-initiating cells are not enriched in cisplatin-surviving BRCA1;p53-deficient mammary tumor cells in vivo', Cell Cycle, 9, pp. 3804 - 3815, http://dx.doi.org/10.4161/cc.9.18.13002
    Journal articles | 2010
    Rottenberg S; Pajic M; Jonkers J, 2010, 'Studying drug resistance using genetically engineered mouse models for breast cancer.', Methods in molecular biology (Clifton, N.J.), 596, pp. 33 - 45, http://dx.doi.org/10.1007/978-1-60761-416-6_3
    Journal articles | 2010
    Scarlett CJ; Chang DK; Stoddart ES; Colvin EK; Mawson A; Jones MD; Tobelmann PE; Pajic M; Daly RJ; Biankin AV, 2010, 'High S100A2 Calcium-Binding Protein Expression Defines a Metastatic Phenotype in Pancreatic Cancer', PANCREAS, 39, pp. 1345 - 1346, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000282946600205&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2010
    Zander SAL; Kersbergen A; Van Der Burg E; De Water N; Van Tellingen O; Gunnarsdottir S; Jaspers JE; Pajic M; Nygren AOH; Jonkers J; Borst P; Rottenberg S, 2010, 'Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan', Cancer Research, 70, pp. 1700 - 1710, http://dx.doi.org/10.1158/0008-5472.CAN-09-3367
    Journal articles | 2009
    Pajic M; Iyer JK; Kersbergen A; Van Der Burg E; Nygren AOH; Jonkers J; Borst P; Rottenberg S, 2009, 'Moderate increase in Mdr1a/1b expression causes in vivo resistance to doxorubicin in a mouse model for hereditary breast cancer', Cancer Research, 69, pp. 6396 - 6404, http://dx.doi.org/10.1158/0008-5472.CAN-09-0041
    Journal articles | 2007
    Chung S; Wei A; Connor DE; Webb GC; Molloy TJ; Pajic M; Diwan AD, 2007, 'Nucleus pulposus cellular longevity by telomerase gene therapy', Spine, 32, pp. 1188 - 1196
    Journal articles | 2007
    Rottenberg S; Nygren AOH; Pajic M; Van Leeuwen FWB; Van Der Heijden I; Van Wetering KD; Liu X; De Visser KE; Gilhuijs KG; Van Tellingen O; Schouten JP; Jonkers J; Borst P, 2007, 'Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer', Proceedings of the National Academy of Sciences of the United States of America, 104, pp. 12117 - 12122, http://dx.doi.org/10.1073/pnas.0702955104
    Journal articles | 2005
    Pajic M; Norris MD; Cohn RJ; Haber M, 2005, 'The role of the multidrug resistance-associated protein 1 gene in neuroblastoma biology and clinical outcome', Cancer Letters, 228, pp. 241 - 246
    Journal articles | 2004
    Pajic M; Bebawy M; Hoskins JM; Roufogalis BD; Rivory LP, 2004, 'Effect of short-term morphine exposure on P-glycoprotein expression and activity in cancer cell lines', Oncology Reports, 11, pp. 1091 - 1095, http://dx.doi.org/10.3892/or.11.5.1091
    Journal articles | 1987
    Ivanovic V; Filipovic V; Pajic M; Santini A, 1987, 'Tertiary dentine formation in dogs' teeth in response to lining materials.', J Dent, 15, pp. 85 - 87, http://dx.doi.org/10.1016/0300-5712(87)90006-6
  • Working Papers | 2020
    Thejer B; Adhikary P; Kaur A; Teakel S; Oosterum AV; Seth I; Pajic M; Hannan K; Pavy M; Poh P; Jazayeri J; Zaw T; Pascovici D; Ludescher M; Pawlak M; Cassano J; Turnbull L; Jazayeri M; James A; Coorey C; Roberts T; Kinder S; Hannan R; Patrick E; Molloy M; J E; Fehm T; Neubauer H; Goldys E; Weston L; CAHILL M, 2020, PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth, http://dx.doi.org10.21203/rs.2.22342/v3
    Working Papers | 2019
    Thejer B; Adhikary P; Kaur A; Teakel S; Van Oosterum A; Seth I; Pajic M; Hannan K; Pavy M; Poh P; Jazayeri J; Zaw T; Pascovici D; Ludescher M; Pawlak M; Cassano J; Turnbull L; Jazayeri M; James A; Coorey C; Roberts T; Kinder S; Hannan R; Patrick E; Molloy M; New E; Fehm T; Neubauer H; Goldys E; Weston L; Cahill M, 2019, PGRMC1 phosphorylation and cell plasticity 1: glycolysis, mitochondria, tumor growth, http://dx.doi.org10.1101/737718
  • Conference Abstracts | 2024
    Pajic M; McLean B; Fajardo DC; Porazinski S; Upton DH; Schuhmacher D; Istadi A; Cox T; Timpson P; Wilcock DJ; Anderson KJ; Mason H; Guisot NE; Jones CD; Phillips C; Armer R, 2024, 'Combining zelasudil, a small molecule ROCK2 inhibitor, with chemotherapy or immunotherapy improves response in preclinical models of pancreatic cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, San Diego, Vol. 84, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2024 - 10 April 2024, http://dx.doi.org/10.1158/1538-7445.AM2024-720
    Conference Abstracts | 2024
    Pitiyarachchi O; Lin FP; Spooner A; Sharbeen G; Barker HP; Thornton K; Collignon E; Ballinger ML; Thomas DM; Magenau A; Porazinski S; Raina A; Sjoquist KM; Chantrill LA; Gebski V; Sowmya A; Timpson P; Pajic M; Goldstein D; Phillips PA, 2024, '1513P Impact of symptom and functional burden on survival in pancreatic ductal adenocarcinoma (PDAC)', in Annals of Oncology, Elsevier BV, Vol. 35, pp. S925 - S925, http://dx.doi.org/10.1016/j.annonc.2024.08.1576
    Conference Abstracts | 2024
    Tyma V; Liew Y-F; Tran A; Howell A; Ritchie S; Atlas AAPCM; Cox T; Pajic M; Herrmann D; Pereira B; Timpson P; Gordon K, 2024, 'Identifying and targeting FOLFIRINOX resistance mechanisms to improve outcomes in pancreatic cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, MA, Boston, Vol. 84, presented at AACR Special Conference in Cancer Research: Advances in Pancreatic Cancer Research, MA, Boston, 15 September 2024 - 18 September 2024, http://dx.doi.org/10.1158/1538-7445.PANCREATIC24-A067
    Conference Abstracts | 2024
    Upton D; Fajardo DC; Omari S; Porazinski S; McLean B; Schuhmacher D; Istadi A; Kothari V; Finkelstein D; Machajewski T; Rock F; Turner S; Pajic M, 2024, 'Selective targeting of integrins αVβ8 and αVβ1 within the dynamic ecosystem of pancreatic cancer to improve the overall anti-tumor response', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, San Diego, Vol. 84, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2024 - 10 April 2024, http://dx.doi.org/10.1158/1538-7445.AM2024-6575
    Conference Abstracts | 2023
    Chacon-Fajardo D; Porazinski S; Man J; Yim H; El-Omar E; Joshua A; Pajic M, 2023, 'Re-purposing non-oncology agent itraconazole to target the dynamic cellular ecosystem of pancreatic cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, MA, Boston, Vol. 84, presented at AACR Special Conference - Pancreatic Cancer, MA, Boston, 27 September 2023 - 30 September 2023, http://dx.doi.org/10.1158/1538-7445.PANCA2023-A029
    Preprints | 2023
    Colino-Sanguino Y; de la Fuente LR; Gloss B; Law A; Handler K; Pajic M; Salomon R; Gallego-Ortega D; Valdes-Mora F, 2023, Performance comparison of high throughput single-cell RNA-Seq platforms in complex tissues, http://dx.doi.org/10.1101/2023.04.04.535585
    Conference Papers | 2023
    Fajardo DC; Moore CL; Porazinski S; McLean B; Borbilas E; Kothari V; Machajewski T; Rock F; Turner SM; Pajic M, 2023, '1467 Selective targeting of integrins αVβ8 and αVβ1 within the dynamic ecosystem of pancreatic cancer to improve the overall anti-tumor response', in Regular and Young Investigator Award Abstracts, BMJ Publishing Group Ltd, pp. A1631 - A1631, presented at SITC 38th Annual Meeting (SITC 2023) Abstracts, http://dx.doi.org/10.1136/jitc-2023-sitc2023.1467
    Conference Abstracts | 2023
    Murphy KJ; Reed DA; Chambers CR; Channon LM; Pajic M; Herrmann D; Timpson P, 2023, 'Anti-fibrotic FAK 'priming' to improve contemporary chemotherapy in pancreatic cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, MA, Boston, Vol. 84, presented at AACR Special Conference - Pancreatic Cancer, MA, Boston, 27 September 2023 - 30 September 2023, http://dx.doi.org/10.1158/1538-7445.PANCA2023-B037
    Conference Abstracts | 2023
    Porazinski S; Man J; Chacon-Fajardo D; Yim H; El-Omar E; Joshua A; Pajic M, 2023, 'The anti-fungal itraconazole improves immunotherapy efficacy in pancreatic ductal adenocarcinoma by reversing the immune-suppressive tumor microenvironment', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, MA, Boston, Vol. 84, presented at AACR Special Conference - Pancreatic Cancer, MA, Boston, 27 September 2023 - 30 September 2023, http://dx.doi.org/10.1158/1538-7445.PANCA2023-C017
    Preprints | 2022
    Kokkinos J; Sharbeen G; Ignacio RM; Pandzic E; Youkhana J; Boyer C; Haghighi K; Gunawarman M; Goldstein D; Gebski V; Pajic M; Pitiyarachchi O; Davis M; Schulstad G; Arkell OSM; Kopecky C; Gonzales-Aloy E; Erkan M; Morton J; Kavallaris M; Gunning P; Hardeman E; Johns A; Gill A; Whan R; Mawson A; Australian Pancreatic Cancer Genome Initiative ; McCarroll J; Phillips P, 2022, βIII-Tubulin is a Brake on Extrinsic Cell-Death in Pancreatic Cancer, http://dx.doi.org/10.1101/2022.09.29.510034
    Conference Abstracts | 2022
    McLean B; Fajardo DC; Istadi A; Porazinski S; Pajic M; Pajic M, 2022, 'EFFECTIVE CO-TARGETING OF FIBROTIC AND IMMUNE MICROENVIRONMENTS TO IMPROVE THE OVERALL ANTI-TUMOUR RESPONSE IN MODELS OF ADVANCED PANCREATIC CANCER', in JOURNAL FOR IMMUNOTHERAPY OF CANCER, BMJ PUBLISHING GROUP, Vol. 10, pp. A1514 - A1514, http://dx.doi.org/10.1136/jitc-2022-SITC2022.1455
    Preprints | 2020
    Kryza T; Khan T; Lovell S; Harrington B; Yin J; Porazinski S; Pajic M; Koistinen H; Rantala J; Dreyer T; Magdolen V; Reuning U; He Y; Tate E; Hooper JD, 2020, Substrate-biased activity-based probes identify the urokinase-plasminogen axis as a master regulator of metastatic signaling by orphan membrane receptor CDCP1, http://dx.doi.org/10.21203/rs.3.rs-92391/v1
    Preprints | 2020
    Thejer BM; Adhikary PP; Kaur A; Teakel SL; Oosterum AV; Seth I; Pajic M; Hannan KM; Pavy M; Poh P; Jazayeri JA; Zaw T; Pascovici D; Ludescher M; Pawlak M; Cassano JC; Turnbull L; Jazayeri M; James AC; Coorey CP; Roberts TL; Kinder SJ; Hannan RD; Patrick E; Molloy MP; J. E; Fehm TN; Neubauer H; Goldys EM; Weston LA; CAHILL M, 2020, PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth, http://dx.doi.org/10.21203/rs.2.22342/v1
    Preprints | 2020
    Thejer BM; Adhikary PP; Kaur A; Teakel SL; Oosterum AV; Seth I; Pajic M; Hannan KM; Pavy M; Poh P; Jazayeri JA; Zaw T; Pascovici D; Ludescher M; Pawlak M; Cassano JC; Turnbull L; Jazayeri M; James AC; Coorey CP; Roberts TL; Kinder SJ; Hannan RD; Patrick E; Molloy MP; J. E; Fehm TN; Neubauer H; Goldys EM; Weston LA; CAHILL M, 2020, PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth, http://dx.doi.org/10.21203/rs.2.22342/v2
    Preprints | 2019
    Dreyer SB; Upstill-Goddard R; Paulus-Hock V; Paris C; Lampraki E-M; Dray E; Serrels B; Caligiuri G; Rebus S; Brunton H; Cunningham R; Nourse C; Bailey U-M; Jones M; Moran-Jones K; Wright DW; Duthie F; Oien K; Evers L; McKay CJ; McGregor GA; Gulati A; Brough R; Bajrami I; Pettitt S; Dziubinski ML; Candido J; Balkwill F; Barry ST; Grützmann R; Rahib L; Johns A; Pajic M; Froeling FEM; Beer P; Musgrove EA; Petersen GM; Ashworth A; Frame MC; Crawford HC; Simeone DM; Lord C; Mukhopadhyay D; Pilarsky C; Cooke SL; Jamieson NB; Morton JP; Sansom OJ; Bailey PJ; Biankin AV; Chang DK, 2019, Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer, http://dx.doi.org/10.1101/713545
    Preprints | 2018
    Wang K; Huynh N; Wang X; Pajic M; Parkin A; Man J; Baldwin G; He H; Nikfarjam M, 2018, The PAK Inhibitor PF-3758309 Promotes the Inhibitory Effects of Multiple Chemotherapeutic Reagents on Patient-Derived Pancreatic Cancer Cell Lines, http://dx.doi.org/10.20944/preprints201809.0322.v1
    Conference Abstracts | 2017
    Chin VT; Nagrial A; Conway J; Vennin C; Chantrill LA; Chou A; Steinmann A; Gill AJ; Humprhis J; Drury A; Froio D; Morgan A; Biankin A; Timpson P; Pajic M, 2017, 'Effect of Rho/ROCK pathway inhibition on metastasis-free and overall survival in biomarker selected, orthotopic, patient-derived models of pancreatic cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, Vol. 35, presented at 53rd Annual Clinical Science Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Symposium on Old Targets, New Drugs - Her2 and MET, IL, Chicago, 02 June 2017 - 07 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.e15759
    Conference Papers | 2016
    Chou A; Steinmann A; Froio D; Drury A; Wohl D; Chin V; Nagrial A; Gill A; Pajic M, 2016, 'Combination of CDK4/6 inhibitor PD-0332991 with standard chemotherapy is synergistic in RB high pancreatic cancer', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, pp. S182 - S182, http://dx.doi.org/10.1016/S0959-8049(16)61645-3
    Conference Abstracts | 2015
    Chin VT; Conway J; Nagrial A; Chantrill LA; Chou A; Steinmann A; Gill A; Pinese M; Wu J; Johns A; Dury A; Biankin A; Timpson P; Pajic M, 2015, 'Targeting the Rho-ROCK pathway to treat pancreatic cancer: The use of unique preclinical models to ascertain the effects on cancer growth and metastasis', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, CA, San Francisco, Vol. 33, presented at Gastrointestinal Cancers Symposium, CA, San Francisco, 15 January 2015 - 17 January 2015, http://dx.doi.org/10.1200/jco.2015.33.3_suppl.312
    Conference Papers | 2014
    Chin V; Nagrial A; Chantrill L; Sjoquist K; O'Connor C; Pajic M; Biankin A; Yip D, 2014, 'PHARMACOLOGIC INTERVENTIONS FOR ADVANCED PANCREATIC CANCER (PC) - A META-ANALYSIS COMPARING GEMCITABINE ALONE (G) VERSUS GEMCITABINE COMBINATIONS (GCs)', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 48 - 48, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339716500014&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2014
    Chin VT; Nagrial A; Chantrill LA; Sjoquist KM; O'Connor C; Pajic M; Blankin AV; Yip D, 2014, 'Targeted therapies in the treatment of advanced pancreatic adenocarcinoma (PC): A systematic review and meta-analysis of randomized trials', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, presented at 50th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 30 May 2014 - 03 June 2014, http://dx.doi.org/10.1200/jco.2014.32.15_suppl.e15209
    Conference Presentations | 2014
    Chou A; Chin VT; Nagrial AM; Gill AJ; Timpson P; Chang DK; Waddell N; Wu J; Grimmond SM; Biankin AV; Pajic M, 2014, 'From functional genomics to precision medicine: Using well annotated models to define personalised treatment strategies for pancreatic cancer', https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000341276000017&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2014
    Nagrial A; Chin V; Steinmann A; Chou A; Grimmond S; Horvath L; Pajic M; Biankin A, 2014, 'GENOMIC CLASSIFIER FOR PANCREATIC DUCTAL ADENOCARCINOMA THERAPEUTIC RESPONSE', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 44 - 44, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339716500009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Presentations | 2014
    Pinho AV; Grimont A; Cowley MJ; Augereau C; Mawson A; Giry-Laterriere M; Van den Steen G; Waddell N; Pajic M; Sempoux C; Wu J; Grimmond SM; Biankin AV; Lemaigre FP; Jacquemin P; Rooman I, 2014, 'SOX9 regulates EGFR/ERBB signaling in pancreatic cancer', presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-LB-73
    Conference Papers | 2013
    Chang DK; Pinese M; Scarlett CJ; Pajic M; Colvin EK; Johns AL; Wu J; Cowley MJ; Humphris JL; Chou A; Nguyen NQ; Nagrial AM; Chantrill L; Chin VT; Musgrove EA; Altekruse S; Gill AJ; Kench JG; Biankin AV, 2013, 'A molecular pre-operative prognostic nomogram for resectable pancreatic cancer', in Cancer Research, American Association for Cancer Research, Washington, DC, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-1156
    Conference Posters | 2013
    Chin V; Nagrial A; Chang D; Chantrill L; Cowley M; Wu J; Spielman C; Steinmann A; Pinese M; Pettitt J; Johns A; Gill A; Timpson P; Biankin A; Pajic M, 2013, 'From function genomics to precision medicine: the therapeutic potential of targeting rock signalling in pancreatic cancer', Chicago, IL, Vol. 9, pp. 53 - 53, presented at ASCO Annual Meeting, Chicago, IL, 31 May 2013 - 04 June 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000329462300024&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2013
    Chin VT; Nagrial A; Chantrill LA; Chang DK; Chou A; Humprhis J; Cowley M; Wu J; DiPetro R; Watson C; Spielman C; Steinmann A; Pinese M; Pettitt J; Johns A; Waddell N; Grimmond S; Timpson P; Biankin AV; Pajic M, 2013, 'From functional genomics to precision medicine: The therapeutic potential of targeting ROCK signaling in pancreatic cancer.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, Vol. 31, presented at 49th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2013 - 04 June 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000335419603693&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Pajic M; Graham PH; Millar EKA; O'Toole SA; Molloy TJ, 2013, 'MicroRNA-regulated pathways of radiotherapy sensitivity and resistance in breast cancer', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, NETHERLANDS, Amsterdam, pp. S232 - S232, presented at European Cancer Congress 2013 - 17th ECCO / 38th ESMO / 32nd ESTRO, NETHERLANDS, Amsterdam, 27 September 2013 - 01 October 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000326843601304&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2012
    Chang DK; Chou A; Nguyen NQ; Nagrial AM; Chantrill LA; Chin VT; Musgrove EA; Sutherland RL; Gill AJ; Altekruse S; Kench JG; Scarlett CJ; Biankin AV; Pinese M; Pajic M; Colvin EK; Johns AL; Humphris JL; Wu J; Cowley MJ, 2012, 'Abstract B64: A molecular preoperative prognostic nomogram for resectable pancreatic cancer.', in Tumor Biology, American Association for Cancer Research, pp. B64 - B64, presented at Abstracts: AACR Special Conference on Pancreatic Cancer: Progress and Challenges; June 18-21, 2012; Lake Tahoe, NV, http://dx.doi.org/10.1158/1538-7445.panca2012-b64
    Conference Abstracts | 2012
    Humphris J; Johns A; Simpson S; Chang D; Cowley MJ; Pajic M; Jones M; Simpson S; Mead S; Biankin A, 2012, 'Risk factors for pancreatic cancer in patients with and without a family history of pancreatic cancer', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, Vol. 27, pp. 127 - 127, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308642600262&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Presentations | 2012
    Humphris J; Tao J; Chang D; Johns A; Cowley MJ; Pajic M; Jones M; Simpson S; Mead S; Biankin A, 2012, 'Somatic mutations in pancreatic ductal adenocarcinoma using amplicon sequencing from formalin fixed paraffin embedded tissue', https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308642600042&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2012
    Molloy T; Pajic M; Holzhauser S; Graham P; Millar EKA; Sutherland RL, 2012, 'Identifying Putative MiRNAs Mediators of Radiotherapy Resistance in Breast Cancer', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, SPAIN, Barcelona, pp. S270 - S270, presented at 22nd Biennial Congress of the European-Association-for-Cancer-Research, SPAIN, Barcelona, 07 July 2012 - 10 July 2012, http://dx.doi.org/10.1016/S0959-8049(12)71723-9
    Conference Abstracts | 2012
    Pajic M; Chang DK; Kassahn KS; Wu J; Cowley M; Waddell N; Johns A; Grimmond SM; Biankin AV, 2012, 'Proffered Paper: Testing Individualised Treatment Strategies in Preclinical Models of Pancreatic Cancer', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, SPAIN, Barcelona, Vol. 48, pp. S22 - S22, presented at 22nd Biennial Congress of the European-Association-for-Cancer-Research, SPAIN, Barcelona, 07 July 2012 - 10 July 2012, http://dx.doi.org/10.1016/S0959-8049(12)70795-5
    Conference Papers | 2010
    Borst P; Rottenberg S; Jonkers J; Zander S; Pajic M; Jaspers J, 2010, 'Abstract PL6-1: Resistance to targeted therapies in a realistic mouse breast cancer model', in Clinical Cancer Research, American Association for Cancer Research (AACR), http://dx.doi.org/10.1158/1078-0432.tcme10-pl6-1
    Conference Papers | 2010
    Rottenberg S; Pajic M; Kersbergen A; Banishki N; Xu G; Jonkers J; Borst P, 2010, 'Abstract A14: Lack of tumor eradication of chemotherapy-sensitive BRCA1;p53-deficient mouse mammary tumors', in Clinical Cancer Research, American Association for Cancer Research (AACR), pp. A14 - A14, http://dx.doi.org/10.1158/1078-0432.tcme10-a14
    Conference Papers | 2006
    Burkhart CA; Watt F; Pajic M; Murray J; Xue C; Flemming C; Smith J; Marshall GM; Haber M; Norris MD; Gudkov AV, 2006, 'Selective Sensitization of murine tumors to chemotherapy by a novel class of non-toxic small molecule inhibitors of MRP1', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454606201252&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2006
    Murray J; Burkhart CA; Watt F; Pajic M; Flemming C; Smith J; Gudkov AV; Haber M; Norris MD, 2006, 'Sensitisation of neuroblastorna tumours to chemotherapy by use of a novel class of MRP1 small molecule inhibitor', in EJC SUPPLEMENTS, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 4, pp. 54 - 54, http://dx.doi.org/10.1016/S1359-6349(06)70175-6
    Preprints |
    Brunton H; Caligiuri G; Cunningham R; Upstill-Goddard R; Bailey U-M; Garner IM; Nourse C; Dreyer S; Jones M; Moran-Jones K; Wright DW; Paulus-Hock V; Nixon C; Thomson G; Jamieson N; McGregor GA; Evers L; McKay CJ; Gulati A; Brough R; Bajrami I; Pettit S; Dziubinski ML; Barry ST; Grützmann R; Brown R; Curry E; Laboratory GPO; Initiative APCG; Pajic M; Musgrove EA; Petersen G; Shanks E; Ashworth A; Crawford HC; Simeone DM; Froeling FEM; Lord CJ; Mukhopadhyay D; Pilarsky C; Grimmond SE; Morton JP; Sansom OJ; Chang DK; Bailey P; Biankin AV, <i>HNF4A</i> and <i>GATA6</i> Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer, http://dx.doi.org/10.2139/ssrn.3430714