Definitive Endoderm

iPSC-derived definitive endoderm cells
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Microscopic visualisation of endoderm cellular structures

Description

Definitive Endoderm derived from pluripotent stem cells can be leveraged to give rise to important tissues such as lung, liver, pancreas and intestines. For those tissues with established protocols, these cells can be used to create reproducible organoids, whilst for those without an established protocol they can be a robust, reproducible starting material for optimisation of culture conditions.

Specifications

    • Pluripotent stem cell derived 
    • Grown in 2D 
    • Cultured as a minimum of 5 days 
    • Available in culture, or as low-passage cryopreserved vials
    • Flow Cytometry 
    • Morphological attributes
    • CD184 
    • SOX17 
    • FOXA2
    • C-Kit

Applications

  • Stem Cell Biology 
  • 3D Culture 
  • Organoids 
  • Drug Screening 
  • Lung Biology 
  • Liver Biology 
  • Intestinal Biology 
  • Pancreatic Biology 
  • Developmental Biology 
  • Regenerative Medicine

Related instruments

Instrument location

3D Culture Facility

Room 2061, Level 2
BioSciences (E26)
UNSW Sydney, NSW 2033
In 3D Culture Facility

Phone: (02) 9348 8212
Email:  3Dculture@unsw.edu.au

Dr Alison Ferguson

Research Manager
  • Phone icon
    Phone
    (02) 9348 8212
  • Send email envelope icon
    Email
    alison.ferguson@unsw.edu.au

Parent facility

3D Culture Facility

The 3D Culture Facility is a centralised, multi-user facility dedicated to advancing therapeutics through innovative 3D culture techniques.

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