MERSCOPE

MERFISH technology that maps and quantifies RNA species in tissues at single-cell resolution
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Merscope

Description

The MERSCOPE from Vizgen is a high-resolution in situ platform powered by MERFISH technology that maps and quantifies RNA species in tissues at single-cell resolution, enabling detailed spatial genomics analysis. It supports flexible experimental setups with customizable gene panels, enhancing cost efficiency and research productivity.

Specifications

  • 1 cm2 of tissue per instrument run
  • 10x and 60x/1.4NA oil objective
  • 1 merscope slide capacity
  • Up to 1000 gene multiplexing capability
  • Back-thinned cooled sCMOS camera with 2048 x 2048 pixel sensor
  • Five laser lines, 405 nm, 475 nm, 545 nm, 635 nm, and 750 nm
  • 16TB data storage
  • Automated transcript decoding

Applications

  • RNA spatial transcriptomics, custom design 140, 300, 500 and 1000 gene panel or pre-designed mouse and human panels

Instrument location

Katharina Gaus Light Microscopy Facility

Level 2
Biosciences (E26)
UNSW Sydney, NSW 2033

Phone: 02 9065 5306
Email: KGlmf@unsw.edu.au

Dr Alex Macmillan

Head of KGLMF
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    Email
    alex.macmillan@unsw.edu.au

Dr Michael Carnell

Senior Lecturer
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    m.carnell@unsw.edu.au

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