Guillain-Barré syndrome (GBS) is a devastating autoimmune disease characterised by a ‘rogue’ immune response against peripheral nerves. Treatment for GBS has remained unchanged for decades and leaves patients with permanent impairments.
Most GBS cases are preceded by infectious causes (ranging from Campylobacter jejuni to COVID19). However, it remains entirely unknown what factors cause the immune response in these people to fail to discriminate between the invading threat and healthy tissues.
This project aims to identify how this autoimmune response develops, by studying the rogue cells that cause the disease in both patients with GBS compared to the normal response using sophisticated mouse models. This project aims to determine the basis of the autoimmune development and set the stage to for the development targeted therapies.
How to Apply
Express your interest in this project by emailing Dr Deborah Burnett. Include a copy of your CV and your academic transcript(s).
School / Research Area
Garvan Institute, St Vincent's Clinical School
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