EpiQuil

Engineering microneedle delivery for lipophilic medicines

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At a glance

  • Optimization graph line icon
    Development stage

    Prototype developed

  • Cash payment coin 1 icon
    Investment stage

    Pre-Seed

  • Startup launch 1 icon
    Commercialisation pathway

    Spinout - staff led

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    Technology readiness level

    TRL 4

  • Gender female icon
    Female led

    Yes

EpiQuil is developing a dissolving microneedle patch to improve drug delivery for people with severe epilepsy.

Investment categories

Healthcare & med tech

  • EpiQuil has developed a dissolving microneedle patch that delivers pharmaceutical cannabidiol through the skin for children and adults with severe drug-resistant epilepsy, replacing the burden of oily oral liquids. Its proprietary platform is designed for lipophilic medicines, such as cannabinoids, for which oral delivery is inherently limited.

  • Cannabidiol is a clinically validated, blockbuster epilepsy medicine, yet it reaches patients only as a high-volume oral oil with variable exposure and a heavy daily burden on families. EpiQuil's dissolving microneedle patch is designed to close that delivery gap, leading with Lennox-Gastaut syndrome ahead of a broader pipeline.

  • Patients living with Lennox-Gastaut Syndrome and their caregivers, paediatric to adult. Prescribed by neurologists and epileptologists in reimbursed markets.

    • Pre-clinical safety complete; animal pharmacokinetic study underway for August 2026 data
    • More than AU$500,000 in non-dilutive funding secured to date
    • End-to-end first-in-human supply chain engaged: API, GMP, clinical investigator
Why invest
Epidiolex passed US$1.1 billion in 2025, validating cannabidiol for drug-resistant epilepsy. Microneedle manufacturing reached clinical scale, making the format failure now solvable.

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