Xylo Bio

Transforming lives with targeted neurotherapeutics

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At a glance

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    Development stage

    Early stage research / proof-of-concept

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    Investment stage

    Series A

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    UNSW affiliation

    Co-located company

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    Technology readiness level

    TRL 4

Why invest
World-class expertise in medicinal chemistry meets cutting-edge computational drug discovery to develop novel small molecules optimised to target specific receptors that promote neuroplasticity.

Xylo is pioneering next-generation therapeutics designed to rewire neural circuits and restore brain function.

By combining advanced neuroscience with computational discovery, Xylo is developing treatments to revolutionise care for neurological and psychiatric conditions. They aim to deliver breakthrough therapies that address critical unmet needs and improve the lives of patients worldwide. 

  • Xylo is building a pipeline of therapies designed to enhance neuroplasticity and address critical gaps in the treatment by harnessing the brain’s ability to rewire and restore function.

    Neuroplasticity offers a transformative approach to treating psychiatric and neurological disorders — whereby underlying dysfunctions can be addressed instead of merely managing symptoms — paving the way for long-term recovery. 

    • Patients with psychiatric and neurological disorders deserve better treatments. Xylo are developing innovative mechanism-based therapies to provide effective solutions for these complex conditions.  
    • By redefining care, Xylo aim to address critical unmet needs and create lasting impact for patients and healthcare systems.
    • Patients with psychiatric & substance-use disorders
    • Individuals with other undisclosed neurological conditions 
    • Xylo has four development programs. Their lead program begins clinical trials in 2026 for major depressive disorder. Xylo’s other programs are in pre-clinical development. 
    • Secured Series Seed funding led by Tenmile and Main Sequence Ventures.
    • Expanding into the US with new HQ while maintaining strong presence on UNSW Kensington campus.

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