Dr. Ospina Stella is a virologist and molecular medicine scientist at the Kirby Institute, whose collaborative research focuses on the characterization of immune responses and their role in the diagnosis, prevention, and treatment of viral infections. His work has directly contributed to the development of new vaccines and immunotherapeutics against COVID-19, including the SpikoGen® vaccine, hyperimmune immunoglobulins, and sotrovimab. Alberto’s research has also been cited in health policy documents by the CDC and public health advisory groups in Canada, Ireland, and Australia.
Other areas of expertise encompass the development and optimization of high-throughput assays, including validation to regulator-licensed and GMP standards as needed. Broader research interests also include antibody engineering, host-pathogen interactions, and host-directed antiviral therapies.
Van Bockel D; Munier CML; Turville S; Badman SG; Walker G; Stella AO; Aggarwal A; Yeang M; Condylios A; Kelleher AD; Applegate TL; Vallely A; Whiley D; Rawlinson W; Cunningham P; Kaldor J; Guy R, 2020, 'Evaluation of commercially available viral transport medium (VTM) for SARS-CoV-2 inactivation and use in point-of-care (POC) testing', Viruses, 12, pp. 1208, http://dx.doi.org/10.3390/v12111208
Journal articles | 2020
Walker G; Clifford V; Bansal N; Stella AO; Turville S; Stelzer-Braid S; Klein L; Rawlinson W, 2020, 'SARS-CoV-2 in human milk is inactivated by Holder pasteurization but not cold storage', , http://dx.doi.org/10.1101/2020.06.18.20134395
Journal articles | 2020
Walker G; Naing Z; Stella AO; Yeang M; Caguicla J; Ramachandran V; Isaacs S; Agapiou D; Bull R; Stelzer-Braid S; Daly J; Gosbell I; Hoad V; Irving D; Pink J; Turville S; Kelleher A; Rawlinson W, 2020, 'SARS Coronavirus-2 microneutralisation and commercial serological assays correlated closely for some but not all enzyme immunoassays', , http://dx.doi.org/10.1101/2020.12.07.20245696
Journal articles | 2020
Walker GJ; Clifford V; Bansal N; Stella AO; Turville S; Stelzer-Braid S; Klein LD; Rawlinson W, 2020, 'SARS-CoV-2 in human milk is inactivated by Holder pasteurisation but not cold storage', Journal of Paediatrics and Child Health, 56, pp. 1872 - 1874, http://dx.doi.org/10.1111/jpc.15065
Journal articles | 2019
Aggarwal A; Ospina Stella A; Henry C; Narayan K; Turville S, 2019, 'HIV corruption of the Arp2/3-Cdc42-IQGAP1 axis to hijack cortical F-Actin to promote cell-cell viral spread', , http://dx.doi.org/10.1101/2019.12.13.873612
Journal articles | 2019
Hu W; Cai Y; Zhu Y; Li F; Stella AO; Tebas P; Mounzer K; Kostman J; Turville S; Montaner L, 2019, 'Cleaving HIV-1 provirus from ART-suppressed patient-derived resting CD4 T Cells using Cpf1/crRNA-array ribonucleotide protein packaged by CD4-targeting lentivirus-like particle', Journal of Virus Eradication, 5, pp. 55 - 56, http://dx.doi.org/10.1016/s2055-6640(20)30221-1
Kaspar D; Auer F; Schardt J; Schindele F; Ospina A; Held C; Ehrenreich A; Scherer S; Müller-Herbst S, 2014, 'Temperature- and nitrogen source-dependent regulation of GlnR target genes in Listeria monocytogenes', FEMS Microbiology Letters, 355, pp. 131 - 141, http://dx.doi.org/10.1111/1574-6968.12458
Preprints | 2025
Aggarwal A; Ognenovska S; Ison T; Fichter C; Milogiannakis V; Afzal M; Stella AO; Waters S; Esneau C; Bartlett N; Pöhlmann S; Hoffmann M; Burrell L; Patel S; Ellis S; Wehrhahn M; Martinez E; Ginn A; Churchill M; Angelovich T; Rawlinson W; Yeang M; Kok J; Sintchenkov V; Parry R; Sng J; Neely G; Moreno C; Loo L; Kelleher A; Brilot F; Khromykh A; Turville S, 2025, Replication of SARS-CoV-2 Omicron lineages is defined by TMPRSS2 use in environments where ACE2 is complexed with solute carriers SLC6A19 and SLC6A20, http://dx.doi.org/10.1101/2025.07.07.663433
Preprints | 2023
Moreno C; Castanheira F; Stella AO; Chung F; Aggarwal A; Cole A; Loo L; Dupuy A; Kong Y; Hagimola L; Fenwick J; Coleman P; Willson M; Bui-Marinos M; Hesselson D; Gamble J; Passam F; Turville S; Kubes P; Neely G, 2023, P-Selectin promotes SARS-CoV-2 interactions with platelets and the endothelium, http://dx.doi.org/10.1101/2023.02.13.528235
Walker G; Clifford V; Bansal N; Stella AO; Turville S; Stelzer-Braid S; Klein L; Rawlinson W, 2020, SARS-CoV-2 in human milk is inactivated by Holder pasteurization but not cold storage, http://dx.doi.org/10.1101/2020.06.18.20134395
Preprints | 2020
Walker G; Naing Z; Stella AO; Yeang M; Caguicla J; Ramachandran V; Isaacs S; Agapiou D; Bull R; Stelzer-Braid S; Daly J; Gosbell I; Hoad V; Irving D; Pink J; Turville S; Kelleher A; Rawlinson W, 2020, SARS Coronavirus-2 microneutralisation and commercial serological assays correlated closely for some but not all enzyme immunoassays, http://dx.doi.org/10.1101/2020.12.07.20245696
Preprints | 2019
Aggarwal A; Ospina Stella A; Henry C; Narayan K; Turville S, 2019, HIV corruption of the Arp2/3-Cdc42-IQGAP1 axis to hijack cortical F-Actin to promote cell-cell viral spread, http://dx.doi.org/10.1101/2019.12.13.873612
Preprints |
Balachandran H; Phetsouphanh C; Agapiou D; Adhikari A; Rodrigo C; Hammoud M; Shrestha LB; Keoshkerian E; Gupta M; Turville S; Christ D; King C; Sasson S; Bartlett A; Grubor-Bauk B; Rawlinson W; Aggarwal A; Stella AO; Klemm V; Mina MM; Post JJ; Hudson B; Gilroy N; Konecny P; Ahlenstiel G; Dwyer D; Sorrell TC; Kelleher A; Tedla N; Lloyd AR; Martinello M; Bull RA, Maintenance of Broad Neutralising Antibodies and Memory B Cells 12 Months Post-Infection Is Predicted by SARS-CoV-2 Specific CD4+ T Cell Responses, http://dx.doi.org/10.2139/ssrn.3920641
