Professor Alexander Swarbrick

Professor Alexander Swarbrick

Conjoint Professor

BSc (Hons) PhD

Medicine & Health
School of Clinical Medicine

Research Interests:

The Swarbrick lab is a multidisciplinary group with the mission to develop new treatment strategies for breast and prostate cancer and melanoma. We study human disease and patient-derived xenografts using advanced cell biology, immunology, molecular biology and computational methods.

We are leaders in the application of cellular genomics to oncology. Single cell and spatial genomics are revolutionizing our understanding of cell biology, immunology and genomics and promise to fuel a new generation of biological insights and treatments for cancer. We have optimised and developed methods to permit high-plex multiomic single cell and tissue analysis, measuring whole transcriptomes, hundreds of protein markers and targeted genome sequences from thousands of cells per sample.

With our close clinical collaborators, we have an active fresh tissue collection program, building unique cohorts of tissue sampled throughout disease progression:

  • Early disease, both untreated and undergoing neoadjuvant therapy

  • Metastatic disease, sampled at relapse and during adjuvant therapy

  • At death from cancer, we harvest multiple metastatic deposits from consenting participants through our rapid autopsy program.

My lab is a multi-disciplinary collaboration of cell biology, pathology, oncology, computation biology and genetics. Its a great place to learn, and great fun.  

https://www.swarbricklab.com/

Broad Research Areas:
Cancer, Cell Biology and Gene Regulation, single cell genomics, cellular genomics, spatial biology, single cell RNA-Seq, animal models, translational research

Specific Research Keywords:
Metastasis, Cell Biology, Molecular Biology, Breast Cancer, prostate cancer, single cell genomics, transcriptomics

Phone
+61-2-9295-8366
Location
Garvan Institute of Medical Research 384 Victoria st Darlinghurst, NSW 2010
  • Book Chapters | 2012
    Swarbrick A, 2012, 'MicroRNAs in cancer stem cells', in MicroRNA in Cancer, pp. 29 - 41, http://dx.doi.org/10.1007/978-94-007-4655-8_3
  • Journal articles | 2024
    Chen J; Larsson L; Swarbrick A; Lundeberg J, 2024, 'Spatial landscapes of cancers: insights and opportunities', Nature Reviews Clinical Oncology, 21, pp. 660 - 674, http://dx.doi.org/10.1038/s41571-024-00926-7
    Journal articles | 2024
    Ciriello G; Magnani L; Aitken SJ; Akkari L; Behjati S; Hanahan D; Landau DA; Lopez-Bigas N; Lupiáñez DG; Marine JC; Martin-Villalba A; Natoli G; Obenauf AC; Oricchio E; Scaffidi P; Sottoriva A; Swarbrick A; Tonon G; Vanharanta S; Zuber J, 2024, 'Cancer Evolution: A Multifaceted Affair', Cancer Discovery, 14, pp. 36 - 48, http://dx.doi.org/10.1158/2159-8290.CD-23-0530
    Journal articles | 2024
    Filipe EC; Velayuthar S; Philp A; Nobis M; Latham SL; Parker AL; Murphy KJ; Wyllie K; Major GS; Contreras O; Mok ETY; Enriquez RF; McGowan S; Feher K; Quek LE; Hancock SE; Yam M; Tran E; Setargew YFI; Skhinas JN; Chitty JL; Phimmachanh M; Han JZR; Cadell AL; Papanicolaou M; Mahmodi H; Kiedik B; Junankar S; Ross SE; Lam N; Coulson R; Yang J; Zaratzian A; Da Silva AM; Tayao M; Chin IL; Cazet A; Kansara M; Segara D; Parker A; Hoy AJ; Harvey RP; Bogdanovic O; Timpson P; Croucher DR; Lim E; Swarbrick A; Holst J; Turner N; Choi YS; Kabakova IV; Philp A; Cox TR, 2024, 'Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism', Advanced Science, 11, http://dx.doi.org/10.1002/advs.202307963
    Journal articles | 2024
    Holliday H; Yang J; Dodson E; Nikolic I; Kamili A; Wheatley M; Deng N; Alexandrou S; Davis TP; Kavallaris M; Caldon CE; McCarroll J; De Preter K; Mestdagh P; Marshall GM; Simpson KJ; Fletcher J; Swarbrick A, 2024, 'Erratum: miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma (Molecular Therapy (2022) 30(3) (1119–1134), (S1525001622000041), (10.1016/j.ymthe.2022.01.004))', Molecular Therapy, 32, pp. 2031 - 2033, http://dx.doi.org/10.1016/j.ymthe.2024.05.008
    Journal articles | 2024
    Meyer B; Stirzaker C; Ramkomuth S; Harvey K; Chan B; Lee CS; Karim R; Deng N; Avery-Kiejda KA; Scott RJ; Lakhani S; Fox S; Robbins E; Shin JS; Beith J; Gill A; Sioson L; Chan C; Krishnaswamy M; Cooper C; Warrier S; Mak C; Rasko JEJ; Bailey CG; Swarbrick A; Clark SJ; O'Toole S; Pidsley R, 2024, 'Detailed DNA methylation characterisation of phyllodes tumours identifies a signature of malignancy and distinguishes phyllodes from metaplastic breast carcinoma', Journal of Pathology, 262, pp. 480 - 494, http://dx.doi.org/10.1002/path.6250
    Journal articles | 2024
    Mo J; Zhang H; Harvey K; Swarbrick A, 2024, 'Abstract C040: Spatial transcriptomics unveils disparities in tumor microenvironment dynamics between breast cancer responders and non-responders', Cancer Research, 84, pp. C040 - C040, http://dx.doi.org/10.1158/1538-7445.tumbody-c040
    Journal articles | 2024
    Pereira BA; Ritchie S; Chambers CR; Gordon KA; Magenau A; Murphy KJ; Nobis M; Tyma VM; Liew YF; Lucas MC; Naeini MM; Barkauskas DS; Chacon-Fajardo D; Howell AE; Parker AL; Warren SC; Reed DA; Lee V; Metcalf XL; Lee YK; O'Regan LP; Zhu J; Trpceski M; Fontaine ARM; Stoehr J; Rouet R; Lin X; Chitty JL; Porazinski S; Wu SZ; Filipe EC; Cadell AL; Holliday H; Yang J; Papanicolaou M; Lyons RJ; Zaratzian A; Tayao M; Da Silva A; Vennin C; Yin J; Dew AB; McMillan PJ; Goldstein LD; Deveson IW; Croucher DR; Samuel MS; Sim HW; Batten M; Chantrill L; Grimmond SM; Gill AJ; Samra J; Jeffry Evans TR; Sasaki T; Phan TG; Swarbrick A; Sansom OJ; Morton JP; Pajic M; Parker BL; Herrmann D; Cox TR; Timpson P, 2024, 'Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response', Science Advances, 10, http://dx.doi.org/10.1126/sciadv.adl1197
    Journal articles | 2024
    Quek C; Pratapa A; Bai X; Al-Eryani G; Pires da Silva I; Mayer A; Bartonicek N; Harvey K; Maher NG; Conway JW; Kasalo RJ; Ben Cheikh B; Braubach O; Palendira U; Saw RPM; Stretch JR; Shannon KF; Menzies AM; Scolyer RA; Long GV; Swarbrick A; Wilmott JS, 2024, 'Single-cell spatial multiomics reveals tumor microenvironment vulnerabilities in cancer resistance to immunotherapy', Cell Reports, 43, http://dx.doi.org/10.1016/j.celrep.2024.114392
    Journal articles | 2024
    Strach MC; Yeung N; Apostolov E; Wang T; Lin H-M; Ansari N; Koh C; Shin J-S; Kench J; Swarbrick A; Horvath L; Mahon KL, 2024, 'Abstract 5480: Single cell and spatial transcriptomic profile of appendiceal tumour peritoneal disease', Cancer Research, 84, pp. 5480 - 5480, http://dx.doi.org/10.1158/1538-7445.am2024-5480
    Journal articles | 2024
    Swarbrick A; Fernandez-Martinez A; Perou CM, 2024, 'Gene-Expression Profiling to Decipher Breast Cancer Inter-and Intratumor Heterogeneity', Cold Spring Harbor Perspectives in Medicine, 14, http://dx.doi.org/10.1101/cshperspect.a041320
    Journal articles | 2024
    Wang T; Roach MJ; Harvey K; Morlanes JE; Kiedik B; Al-Eryani G; Greenwald A; Kalavros N; Dezem FS; Ma Y; Pita-Juarez YH; Wise K; Degletagne C; Elz A; Hadadianpour A; Johanneson J; Pakiam F; Ryu H; Newell EW; Tonon L; Kohlway A; Drennon T; Abousoud J; Stott R; Lund P; Durruthy J; Vallejo AF; Li W; Salomon R; Kaczorowski D; Warren J; Butler LM; O’Toole S; Plummer J; Vlachos IS; Lundeberg J; Swarbrick A; Martelotto LG, 2024, 'snPATHO-seq, a versatile FFPE single-nucleus RNA sequencing method to unlock pathology archives', Communications Biology, 7, http://dx.doi.org/10.1038/s42003-024-07043-2
    Journal articles | 2023
    Bai X; Quek C; Al-Eryani G; Harvey K; Silva I; Menzies AM; Swarbrick A; Long GV; Scolyer R; Wilmott J, 2023, '1165P Single cell spatial features of in-transit melanoma associated with patient outcome to immunotherapy', Annals of Oncology, 34, pp. S694 - S694, http://dx.doi.org/10.1016/j.annonc.2023.09.2981
    Journal articles | 2023
    Chaudagar K; Hieromnimon HM; Khurana R; Labadie B; Hirz T; Mei S; Hasan R; Shafran J; Kelley A; Apostolov E; Al-Eryani G; Harvey K; Rameshbabu S; Loyd M; Bynoe K; Drovetsky C; Solanki A; Markiewicz E; Zamora M; Fan X; Schürer S; Swarbrick A; Sykes DB; Patnaik A, 2023, 'Reversal of Lactate and PD-1–mediated Macrophage Immunosuppression Controls Growth of PTEN/p53-deficient Prostate Cancer', Clinical Cancer Research, 29, pp. 1952 - 1968, http://dx.doi.org/10.1158/1078-0432.CCR-22-3350
    Journal articles | 2023
    Chen J; Ruan T; Wu S; Lim E; Swarbrick A, 2023, '11P Targeting stromal cells to reverse immune suppression in triple-negative breast cancer', Annals of Oncology, 34, pp. S190 - S190, http://dx.doi.org/10.1016/j.annonc.2023.09.1514
    Journal articles | 2023
    Prekovic S; Chalkiadakis T; Roest M; Roden D; Lutz C; Schuurman K; Opdam M; Hoekman L; Abbott N; Tesselaar T; Wajahat M; Dwyer AR; Mayayo-Peralta I; Gomez G; Altelaar M; Beijersbergen R; Győrffy B; Young L; Linn S; Jonkers J; Tilley W; Hickey T; Vareslija D; Swarbrick A; Zwart W, 2023, 'Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity', EMBO Molecular Medicine, 15, http://dx.doi.org/10.15252/emmm.202317737
    Journal articles | 2023
    Quek C; Pratapa A; da Silva IP; Al-Eryani G; Mayer A; Bartonicek N; Harvey K; Braubach O; Saw RPM; Stretch J; Shannon KF; Menzies AM; Scolyer RA; Long GV; Swarbrick A; Wilmott JS, 2023, 'Abstract 4621: Distinct spatial and molecular maps in the tumour microenvironment of resistant melanoma patients treated with checkpoint inhibitor immunotherapy', Cancer Research, 83, pp. 4621 - 4621, http://dx.doi.org/10.1158/1538-7445.am2023-4621
    Journal articles | 2023
    Thai LM; O'Reilly L; Reibe-Pal S; Sue N; Holliday H; Small L; Schmitz-Peiffer C; Dhenni R; Wang-Wei Tsai V; Norris N; Yau B; Zhang X; Lee K; Yan C; Shi YC; Kebede MA; Brink R; Cooney GJ; Irvine KM; Breit SN; Phan TG; Swarbrick A; Biden TJ, 2023, 'β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling', iScience, 26, http://dx.doi.org/10.1016/j.isci.2023.106477
    Journal articles | 2023
    Thankamony AP; Ramkomuth S; Ramesh ST; Murali R; Chakraborty P; Karthikeyan N; Varghese BA; Jaikumar VS; Jolly MK; Swarbrick A; Nair R, 2023, 'Phenotypic heterogeneity drives differential disease outcome in a mouse model of triple negative breast cancer', Frontiers in Oncology, 13, http://dx.doi.org/10.3389/fonc.2023.1230647
    Journal articles | 2023
    Tran KA; Addala V; Johnston RL; Lovell D; Bradley A; Koufariotis LT; Wood S; Wu SZ; Roden D; Al-Eryani G; Swarbrick A; Williams ED; Pearson JV; Kondrashova O; Waddell N, 2023, 'Performance of tumour microenvironment deconvolution methods in breast cancer using single-cell simulated bulk mixtures', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-41385-5
    Journal articles | 2023
    Vail ME; Farnsworth RH; Hii L; Allen S; Arora S; Anderson RL; Dickins RA; Orimo A; Wu SZ; Swarbrick A; Scott AM; Janes PW, 2023, 'Inhibition of EphA3 Expression in Tumour Stromal Cells Suppresses Tumour Growth and Progression', Cancers, 15, http://dx.doi.org/10.3390/cancers15184646
    Journal articles | 2023
    Zhai L; Balachandran A; Larkin R; Seneviratne JA; Chung SA; Lalwani A; Tsubota S; Beck D; Kadomatsu K; Beckers A; Durink K; De Preter K; Speleman F; Haber M; Norris MD; Swarbrick A; Cheung BB; Marshall GM; Carter DR, 2023, 'Mitotic Dysregulation at Tumor Initiation Creates a Therapeutic Vulnerability to Combination Anti-Mitotic and Pro-Apoptotic Agents for MYCN-Driven Neuroblastoma', International Journal of Molecular Sciences, 24, http://dx.doi.org/10.3390/ijms242115571
    Journal articles | 2022
    Al-Eryani G; Swarbrick A, 2022, 'Spatial maps of genetically diverse breast cancer cells', Nature, 611, pp. 458 - 459, http://dx.doi.org/10.1038/d41586-022-03560-4
    Journal articles | 2022
    Anderson AC; Yanai I; Yates LR; Wang L; Swarbrick A; Sorger P; Santagata S; Fridman WH; Gao Q; Jerby L; Izar B; Shang L; Zhou X, 2022, 'Spatial transcriptomics', Cancer Cell, 40, pp. 895 - 900, http://dx.doi.org/10.1016/j.ccell.2022.08.021
    Journal articles | 2022
    Baldwin LA; Bartonicek N; Yang J; Wu SZ; Deng N; Roden DL; Chan CL; Al-Eryani G; Zanker DJ; Parker BS; Swarbrick A; Junankar S, 2022, 'DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and immunotherapy response', Nature Communications, 13, http://dx.doi.org/10.1038/s41467-022-34041-x
    Journal articles | 2022
    Crist SB; Nemkov T; Dumpit RF; Dai J; Tapscott SJ; True LD; Swarbrick A; Sullivan LB; Nelson PS; Hansen KC; Ghajar CM, 2022, 'Publisher Correction: Unchecked oxidative stress in skeletal muscle prevents outgrowth of disseminated tumour cells (Nature Cell Biology, (2022), 24, 4, (538-553), 10.1038/s41556-022-00881-4)', Nature Cell Biology, 24, pp. 1177, http://dx.doi.org/10.1038/s41556-022-00945-5
    Journal articles | 2022
    Crist SB; Nemkov T; Dumpit RF; Dai J; Tapscott SJ; True LD; Swarbrick A; Sullivan LB; Nelson PS; Hansen KC; Ghajar CM, 2022, 'Unchecked oxidative stress in skeletal muscle prevents outgrowth of disseminated tumour cells', Nature Cell Biology, 24, pp. 538 - 553, http://dx.doi.org/10.1038/s41556-022-00881-4
    Journal articles | 2022
    Deng N; Minoche A; Harvey K; Li M; Winkler J; Goga A; Swarbrick A, 2022, 'Deep whole genome sequencing identifies recurrent genomic alterations in commonly used breast cancer cell lines and patient-derived xenograft models', Breast Cancer Research, 24, http://dx.doi.org/10.1186/s13058-022-01540-0
    Journal articles | 2022
    Holliday H; Yang J; Dodson E; Nikolic I; Kamili A; Wheatley M; Deng N; Alexandrou S; Davis TP; Kavallaris M; Caldon CE; McCarroll J; De Preter K; Mestdagh P; Marshall GM; Simpson KJ; Fletcher J; Swarbrick A, 2022, 'miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma', Molecular Therapy, 30, pp. 1119 - 1134, http://dx.doi.org/10.1016/j.ymthe.2022.01.004
    Journal articles | 2022
    Masle-Farquhar E; Jackson KJL; Peters TJ; Al-Eryani G; Singh M; Payne KJ; Rao G; Avery DT; Apps G; Kingham J; Jara CJ; Skvortsova K; Swarbrick A; Ma CS; Suan D; Uzel G; Chua I; Leiding JW; Heiskanen K; Preece K; Kainulainen L; O'Sullivan M; Cooper MA; Seppänen MRJ; Mustjoki S; Brothers S; Vogel TP; Brink R; Tangye SG; Reed JH; Goodnow CC, 2022, 'STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation', Immunity, 55, pp. 2386 - 2404.e8, http://dx.doi.org/10.1016/j.immuni.2022.11.001
    Journal articles | 2022
    Papanicolaou M; Parker AL; Yam M; Filipe EC; Wu SZ; Chitty JL; Wyllie K; Tran E; Mok E; Nadalini A; Skhinas JN; Lucas MC; Herrmann D; Nobis M; Pereira BA; Law AMK; Castillo L; Murphy KJ; Zaratzian A; Hastings JF; Croucher DR; Lim E; Oliver BG; Mora FV; Parker BL; Gallego-Ortega D; Swarbrick A; O’Toole S; Timpson P; Cox TR, 2022, 'Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis', Nature Communications, 13, http://dx.doi.org/10.1038/s41467-022-32255-7
    Journal articles | 2022
    Roden D; Swarbrick A, 2022, 'Mapping the cancer cell states conserved across solid tumors', Nature Genetics, 54, pp. 1066 - 1067, http://dx.doi.org/10.1038/s41588-022-01151-7
    Journal articles | 2021
    Andersson A; Larsson L; Stenbeck L; Salmén F; Ehinger A; Wu SZ; Al-Eryani G; Roden D; Swarbrick A; Borg Å; Frisén J; Engblom C; Lundeberg J, 2021, 'Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions', Nature Communications, 12, http://dx.doi.org/10.1038/s41467-021-26271-2
    Journal articles | 2021
    Baldwin L; Bartonicek N; Yang J; Wu S; Deng N; Roden D; Chan C-L; Al-Eryani G; Zanker D; Parker B; Parker B; Swarbrick A; Junankar S, 2021, 'DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and in response to immunotherapy', , http://dx.doi.org/10.1101/2021.01.11.426174
    Journal articles | 2021
    Bergholtz H; Carter JM; Cesano A; Cheang MCU; Church SE; Divakar P; Fuhrman CA; Goel S; Gong J; Guerriero JL; Hoang ML; Hwang ES; Kuasne H; Lee J; Liang Y; Mittendorf EA; Perez J; Prat A; Pusztai L; Reeves JW; Riazalhosseini Y; Richer JK; Sahin Ö; Sato H; Schlam I; Sørlie T; Stover DG; Swain SM; Swarbrick A; Thompson EA; Tolaney SM; Warren SE, 2021, 'Best practices for spatial profiling for breast cancer research with the GeoMx® digital spatial profiler', Cancers, 13, http://dx.doi.org/10.3390/cancers13174456
    Journal articles | 2021
    Chew NJ; Lim Kam Sian TCC; Nguyen EV; Shin SY; Yang J; Hui MN; Deng N; McLean CA; Welm AL; Lim E; Gregory P; Nottle T; Lang T; Vereker M; Richardson G; Kerr G; Micati D; Jardé T; Abud HE; Lee RS; Swarbrick A; Daly RJ, 2021, 'Evaluation of FGFR targeting in breast cancer through interrogation of patient-derived models', Breast Cancer Research, 23, http://dx.doi.org/10.1186/s13058-021-01461-4
    Journal articles | 2021
    Deng N; Minoche A; Harvey K; Goga A; Swarbrick A, 2021, 'Deep whole genome sequencing identifies recurrent genomic alterations in commonly-used breast cancer cell lines and patient derived xenograft models', , http://dx.doi.org/10.21203/rs.3.rs-859624/v1
    Journal articles | 2021
    Hickey TE; Selth LA; Chia KM; Laven-Law G; Milioli HH; Roden D; Jindal S; Hui M; Finlay-Schultz J; Ebrahimie E; Birrell SN; Stelloo S; Iggo R; Alexandrou S; Caldon CE; Abdel-Fatah TM; Ellis IO; Zwart W; Palmieri C; Sartorius CA; Swarbrick A; Lim E; Carroll JS; Tilley WD, 2021, 'The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer', Nature Medicine, 27, pp. 310 - 320, http://dx.doi.org/10.1038/s41591-020-01168-7
    Journal articles | 2021
    Holliday H; Khoury A; Swarbrick A, 2021, 'Chromatin immunoprecipitation of transcription factors and histone modifications in Comma-Dβ mammary epithelial cells', STAR Protocols, 2, http://dx.doi.org/10.1016/j.xpro.2021.100514
    Journal articles | 2021
    Holliday H; Roden D; Junankar S; Wu SZ; Baker LA; Krisp C; Chan CL; McFarland A; Skhinas JN; Cox TR; Pal B; Huntington ND; Ormandy CJ; Carroll JS; Visvader J; Molloy MP; Swarbrick A, 2021, 'Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB', iScience, 24, http://dx.doi.org/10.1016/j.isci.2021.102072
    Journal articles | 2021
    McEvoy CR; Holliday H; Thio N; Mitchell C; Choong DY; Yellapu B; Leong HS; Xu H; Lade S; Browning J; Takano EA; Byrne DJ; Gill AJ; Duong CP; Li J; Fellowes AP; Fox SB; Swarbrick A; Prall OWJ, 2021, 'A MXI1-NUTM1 fusion protein with MYC-like activity suggests a novel oncogenic mechanism in a subset of NUTM1-rearranged tumors', Laboratory Investigation, 101, pp. 26 - 37, http://dx.doi.org/10.1038/s41374-020-00484-3
    Journal articles | 2021
    Meyer B; Clifton S; Locke W; Luu PL; Du Q; Lam D; Armstrong NJ; Kumar B; Deng N; Harvey K; Swarbrick A; Ganju V; Clark SJ; Pidsley R; Stirzaker C, 2021, 'Identification of DNA methylation biomarkers with potential to predict response to neoadjuvant chemotherapy in triple-negative breast cancer', Clinical Epigenetics, 13, http://dx.doi.org/10.1186/s13148-021-01210-6
    Journal articles | 2021
    Mulder K; Patel AA; Kong WT; Piot C; Halitzki E; Dunsmore G; Khalilnezhad S; Irac SE; Dubuisson A; Chevrier M; Zhang XM; Tam JKC; Lim TKH; Wong RMM; Pai R; Khalil AIS; Chow PKH; Wu SZ; Al-Eryani G; Roden D; Swarbrick A; Chan JKY; Albani S; Derosa L; Zitvogel L; Sharma A; Chen J; Silvin A; Bertoletti A; Blériot C; Dutertre CA; Ginhoux F, 2021, 'Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease', Immunity, 54, pp. 1883 - 1900.e5, http://dx.doi.org/10.1016/j.immuni.2021.07.007
    Journal articles | 2021
    Wu SZ; Al-Eryani G; Roden DL; Junankar S; Harvey K; Andersson A; Thennavan A; Wang C; Torpy JR; Bartonicek N; Wang T; Larsson L; Kaczorowski D; Weisenfeld NI; Uytingco CR; Chew JG; Bent ZW; Chan CL; Gnanasambandapillai V; Dutertre CA; Gluch L; Hui MN; Beith J; Parker A; Robbins E; Segara D; Cooper C; Mak C; Chan B; Warrier S; Ginhoux F; Millar E; Powell JE; Williams SR; Liu XS; O’Toole S; Lim E; Lundeberg J; Perou CM; Swarbrick A, 2021, 'A single-cell and spatially resolved atlas of human breast cancers', Nature Genetics, 53, pp. 1334 - 1347, http://dx.doi.org/10.1038/s41588-021-00911-1
    Journal articles | 2021
    Wu SZ; Roden DL; Al-Eryani G; Bartonicek N; Harvey K; Cazet AS; Chan CL; Junankar S; Hui MN; Millar EA; Beretov J; Horvath L; Joshua AM; Stricker P; Wilmott JS; Quek C; Long GV; Scolyer RA; Yeung BZ; Segara D; Mak C; Warrier S; Powell JE; O’Toole S; Lim E; Swarbrick A, 2021, 'Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis', Genome Medicine, 13, http://dx.doi.org/10.1186/s13073-021-00885-z
    Journal articles | 2021
    Wu SZ; Swarbrick A, 2021, 'Single-cell advances in stromal-leukocyte interactions in cancer', Immunological Reviews, 302, pp. 286 - 298, http://dx.doi.org/10.1111/imr.12976
    Journal articles | 2020
    Andersson A; Larsson L; Stenbeck L; Salmén F; Ehinger A; Wu S; Al-Eryani G; Roden D; Swarbrick A; Borg Å; Frisén J; Engblom C; Lundeberg J, 2020, 'Spatial Deconvolution of HER2-positive Breast Tumors Reveals Novel Intercellular Relationships', bioRxiv, http://dx.doi.org/10.1101/2020.07.14.200600
    Journal articles | 2020
    Baker LA; Holliday H; Roden D; Krisp C; Wu SZ; Junankar S; Junankar S; Serandour AA; Mohammed H; Nair R; Sankaranarayanan G; Law AMK; McFarland A; Simpson PT; Lakhani S; Dodson E; Selinger C; Anderson L; Samimi G; Hacker NF; Lim E; Ormandy CJ; Naylor MJ; Simpson K; Nikolic I; O'Toole S; Kaplan W; Cowley MJ; Carroll JS; Molloy M; Swarbrick A, 2020, 'Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer', Breast Cancer Research, 22, http://dx.doi.org/10.1186/s13058-020-01306-6
    Journal articles | 2020
    Holliday H; Roden D; Junankar S; Wu S; Baker L; Krisp C; Chan C-L; McFarland A; Skhinas J; Cox T; Pal B; Huntington N; Ormandy C; Carroll J; Visvader J; Molloy M; Swarbrick A, 2020, 'Inhibitor of Differentiation 4 (ID4) represses myoepithelial differentiation of mammary stem cells through its interaction with HEB', , http://dx.doi.org/10.1101/2020.04.06.026963
    Journal articles | 2020
    Hoque M; Elmaghrabi YA; Köse M; Beevi SS; Jose J; Meneses-Salas E; Blanco-Muñoz P; Conway JRW; Swarbrick A; Timpson P; Tebar F; Enrich C; Rentero C; Grewal T, 2020, 'Annexin A6 improves anti-migratory and anti-invasive properties of tyrosine kinase inhibitors in EGFR overexpressing human squamous epithelial cells', FEBS Journal, 287, pp. 2961 - 2978, http://dx.doi.org/10.1111/febs.15186
    Journal articles | 2020
    Millar EKA; Browne LH; Beretov J; Lee K; Lynch J; Swarbrick A; Graham PH, 2020, 'Tumour stroma ratio assessment using digital image analysis predicts survival in triple negative and luminal breast cancer', Cancers, 12, pp. 1 - 14, http://dx.doi.org/10.3390/cancers12123749
    Journal articles | 2020
    Owen KL; Gearing LJ; Zanker DJ; Brockwell NK; Khoo WH; Roden DL; Cmero M; Mangiola S; Hong MK; Spurling AJ; McDonald M; Chan CL; Pasam A; Lyons RJ; Duivenvoorden HM; Ryan A; Butler LM; Mariadason JM; Giang Phan T; Hayes VM; Sandhu S; Swarbrick A; Corcoran NM; Hertzog PJ; Croucher PI; Hovens C; Parker BS, 2020, 'Prostate cancer cell-intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone', EMBO Reports, 21, http://dx.doi.org/10.15252/embr.202050162
    Journal articles | 2020
    Piggin CL; Roden DL; Law AMK; Molloy MP; Krisp C; Swarbrick A; Naylor MJ; Kalyuga M; Kaplan W; Oakes SR; Gallego-Ortega D; Clark SJ; Carroll JS; Bartonicek N; Ormandy CJ, 2020, 'ELF5 modulates the estrogen receptor cistrome in breast cancer', PLoS Genetics, 16, http://dx.doi.org/10.1371/journal.pgen.1008531
    Journal articles | 2020
    Portman N; Milioli HH; Alexandrou S; Coulson R; Yong A; Fernandez KJ; Chia KM; Halilovic E; Segara D; Parker A; Haupt S; Haupt Y; Tilley WD; Swarbrick A; Caldon CE; Lim E, 2020, 'MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer', Breast Cancer Research, 22, pp. 87, http://dx.doi.org/10.1186/s13058-020-01318-2
    Journal articles | 2020
    Portman N; Milioli HH; Alexandrou S; Coulson R; Yong A; Fernandez KJ; Chia KM; Segara D; Parker A; Haupt S; Haupt Y; Tilley WD; Swarbrick A; Caldon CE; Lim E, 2020, 'MDM2 Inhibition in Combination with Endocrine Therapy and CDK4/6 Inhibition for the Treatment of ER-Positive Breast Cancer', , http://dx.doi.org/10.1101/2020.06.09.140921
    Journal articles | 2020
    Teo WS; Holliday H; Karthikeyan N; Cazet AS; Roden DL; Harvey K; Konrad CV; Murali R; Varghese BA; Thankamony AP; Chan CL; McFarland A; Junankar S; Ye S; Yang J; Nikolic I; Shah JS; Baker LA; Millar EKA; Naylor MJ; Ormandy CJ; Lakhani SR; Kaplan W; Mellick AS; O'Toole SA; Swarbrick A; Nair R, 2020, 'Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1', Frontiers in Cell and Developmental Biology, 8, http://dx.doi.org/10.3389/fcell.2020.00552
    Journal articles | 2020
    Thankamony AP; Murali R; Karthikeyan N; Varghese BA; Teo WS; McFarland A; Roden DL; Holliday H; Konrad CV; Cazet A; Dodson E; Yang J; Baker LA; George JT; Levine H; Jolly MK; Swarbrick A; Nair R, 2020, 'Targeting the id1-kif11 axis in triple-negative breast cancer using combination therapy', Biomolecules, 10, pp. 1 - 15, http://dx.doi.org/10.3390/biom10091295
    Journal articles | 2020
    Wu S; Roden D; Al-Eryani G; Bartonicek N; Harvey K; Cazet A; Chan C-L; Junankar S; Hui M; Millar E; Beretov J; Horvath L; Joshua A; Stricker P; Wilmott J; Quek C; Long G; Scolyer R; Yeung B; Segara D; Mak C; Warrier S; Powell J; O'Toole S; Lim E; Swarbrick A, 2020, 'Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis', bioRxiv, http://dx.doi.org/10.1101/2020.06.04.135277
    Journal articles | 2020
    Wu S; Roden D; Wang C; Holliday H; Harvey K; Cazet A; Murphy K; Pereira B; Al-Eryani G; Bartonicek N; Hou R; Torpy J; Junankar S; Chan C-L; Lam E; Hui M; Gluch L; Beith J; Parker A; Robbins E; Segara D; Mak C; Cooper C; Warrier S; Forrest A; Powell J; O’Toole S; Cox T; Timpson P; Lim E; Liu S; Swarbrick A, 2020, 'Single-cell analysis reveals diverse stromal subsets associated with immune evasion in triple-negative breast cancer', bioRxiv, http://dx.doi.org/10.1101/2020.06.04.135327
    Journal articles | 2020
    Wu SZ; Roden DL; Wang C; Holliday H; Harvey K; Cazet AS; Murphy KJ; Pereira B; Al-Eryani G; Bartonicek N; Hou R; Torpy JR; Junankar S; Chan CL; Lam CE; Hui MN; Gluch L; Beith J; Parker A; Robbins E; Segara D; Mak C; Cooper C; Warrier S; Forrest A; Powell J; O'Toole S; Cox TR; Timpson P; Lim E; Liu XS; Swarbrick A, 2020, 'Stromal cell diversity associated with immune evasion in human triple-negative breast cancer', EMBO Journal, 39, pp. embj2019104063, http://dx.doi.org/10.15252/embj.2019104063
    Journal articles | 2020
    Yang Y; Cooper C; Robbins E; Swarbrick A; Harvey K; Lim E; Mak C; Carmalt H; Warrier S; Chan B; Beith J; Hui M; Gluch L; O’Toole S; Cooper W, 2020, '9. Factors influencing the success rate of patient derived xenograft formation from breast cancer specimens', Pathology, 52, pp. S136 - S136, http://dx.doi.org/10.1016/j.pathol.2020.01.010
    Journal articles | 2019
    Brockwell NK; Rautela J; Owen KL; Gearing LJ; Deb S; Harvey K; Spurling A; Zanker D; Chan CL; Cumming HE; Deng N; Zakhour JM; Duivenvoorden HM; Robinson T; Harris M; White M; Fox J; Ooi C; Kumar B; Thomson J; Potasz N; Swarbrick A; Hertzog PJ; Molloy TJ; Toole SO; Ganju V; Parker BS, 2019, 'Tumor inherent interferon regulators as biomarkers of long-term chemotherapeutic response in TNBC', npj Precision Oncology, 3, http://dx.doi.org/10.1038/s41698-019-0093-2
    Journal articles | 2019
    Castillo L; George S; Lin H-M; Yeung N; Mawson A; Young AI; Law AM; Hastings J; Gallego-Ortega D; Deng N; Croucher D; Swarbrick A; Horvath L; Ormandy CJ; Oakes SR, 2019, 'Flicking the switch off, targeting MCL-1 in the treatment of breast and prostate cancer', Oncology Abstracts, http://dx.doi.org/10.1530/oncolabs.1.p038
    Journal articles | 2019
    Cazet A; Hui M; Elsworth B; Wu S; Roden D; Chan C-L; O'Toole S; Watkins DN; Taylor R; Cox T; Samuel M; Martin M; Swarbrick A, 2019, 'Targeting stromal remodelling and cancer stem cell plasticity overcomes chemoresistance in metastatic triple negative breast cancer', Oncology Abstracts, http://dx.doi.org/10.1530/oncolabs.1.p009
    Journal articles | 2019
    Chia KM; Milioli H; Portman N; Laven-Law G; Coulson R; Yong A; Segara D; Parker A; Caldon CE; Deng N; Swarbrick A; Tilley WD; Hickey TE; Lim E, 2019, 'Non-canonical AR activity facilitates endocrine resistance in breast cancer', Endocrine-Related Cancer, 26, pp. 251 - 264, http://dx.doi.org/10.1530/ERC-18-0333
    Journal articles | 2019
    Khoo WH; Ledergor G; Weiner A; Roden DL; Terry RL; McDonald MM; Chai RC; De Veirman K; Owen KL; Opperman KS; Vandyke K; Clark JR; Seckinger A; Kovacic N; Nguyen A; Mohanty ST; Pettitt JA; Xiao Y; Corr AP; Seeliger C; Novotny M; Lasken RS; Nguyen TV; Oyajobi BO; Aftab D; Swarbrick A; Parker B; Hewett DR; Hose D; Vanderkerken K; Zannettino ACW; Amit I; Phan TG; Croucher PI, 2019, 'A niche-dependent myeloid transcriptome signature defines dormant myeloma cells', Blood, 134, pp. 30 - 43, http://dx.doi.org/10.1182/blood.2018880930
    Journal articles | 2019
    McCabe M; Gauthier M-E; Chan C-L; Thompson T; De Sousa S; Puttick C; Grady J; Gayevskiy V; Tao J; Ying K; Cipponi A; Deng N; Swarbrick A; Thomas M; kConFab ; Lord R; Johns A; Kohonen-Corish M; O'Toole S; Clark J; Mueller S; Gupta R; McCormack A; Dinger M; Cowley M; Bastick P; Friedlander M; Colley A; Andrews L; Young M-A; Tucker K; Williams R, 2019, 'Development and validation of a targeted gene sequencing panel for application to disparate cancers', Scientific Reports, 9, pp. 17052, http://dx.doi.org/10.1038/s41598-019-52000-3
    Journal articles | 2019
    Money A-M; Schaverin J; Aubel P; Neist E; Owens T; Swarbrick A; Taniuchi I; Ormandy CJ; Simpson PT; Naylor MJ, 2019, 'Novel role of CBF[beta] as a regulator of breast cancer phenotype, progression and metastasis', Oncology Abstracts, http://dx.doi.org/10.1530/oncolabs.1.p037
    Journal articles | 2019
    Roden D; Wu S; Harvey K; Chan C-L; Al-Eryani G; Cazet A; Lim E; Swarbrick A, 2019, 'Single-cell transcriptomics reveals marked heterogeneity for intrinsic molecular subtype and cellular function in estrogen receptor positive breast cancer', Oncology Abstracts, http://dx.doi.org/10.1530/oncolabs.1.p045
    Journal articles | 2019
    Singh M; Al-Eryani G; Carswell S; Ferguson JM; Blackburn J; Barton K; Roden D; Luciani F; Giang Phan T; Junankar S; Jackson K; Goodnow CC; Smith MA; Swarbrick A, 2019, 'High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes', Nature Communications, 10, http://dx.doi.org/10.1038/s41467-019-11049-4
    Journal articles | 2018
    Baker L; Krisp C; Roden D; Holliday H; Wu S; Junankar S; Serandour A; Mohammed H; Nair R; Chan C-L; Yang J; Foreman N; Fitzpatrick B; Sankaranarayanan G; Law AMK; Ormandy C; Naylor M; McFarland A; Simpson P; Lakhani S; O'Toole S; Selinger C; Anderson L; Samimi G; Hacker N; Kaplan W; Carroll J; Molloy M; Swarbrick A, 2018, 'A novel role for the HLH protein Inhibitor of Differentiation 4 (ID4) in the DNA damage response in basal-like breast cancer.', BIORXIV, http://dx.doi.org/10.1101/281196
    Journal articles | 2018
    Cazet AS; Hui MN; Elsworth BL; Wu SZ; Roden D; Chan CL; Skhinas JN; Collot R; Yang J; Harvey K; Johan MZ; Cooper C; Nair R; Herrmann D; McFarland A; Deng N; Ruiz-Borrego M; Rojo F; Trigo JM; Bezares S; Caballero R; Lim E; Timpson P; O’Toole S; Watkins DN; Cox TR; Samuel MS; Martín M; Swarbrick A; O'Toole S, 2018, 'Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer', Nature Communications, 9, pp. 2897, http://dx.doi.org/10.1038/s41467-018-05220-6
    Journal articles | 2018
    Holliday H; Baker LA; Junankar SR; Clark SJ; Swarbrick A, 2018, 'Epigenomics of mammary gland development', Breast Cancer Research, 20, http://dx.doi.org/10.1186/s13058-018-1031-x
    Journal articles | 2018
    Lin H-M; Nikolic I; Yang J; Castillo L; Deng N; Chan C-L; Yeung N; Dodson E; Elsworth B; Spielman C; Lee B; Boyer Z; Simpson K; Daly R; Horvath L; Swarbrick A, 2018, 'MicroRNAs as potential therapeutics to enhance chemosensitivity in advanced prostate cancer', , http://dx.doi.org/10.1101/273284
    Journal articles | 2018
    Lin HM; Nikolic I; Yang J; Castillo L; Deng N; Chan CL; Yeung NK; Dodson E; Elsworth B; Spielman C; Lee BY; Boyer Z; Simpson KJ; Daly RJ; Horvath LG; Swarbrick A, 2018, 'MicroRNAs as potential therapeutics to enhance chemosensitivity in advanced prostate cancer', Scientific Reports, 8, http://dx.doi.org/10.1038/s41598-018-26050-y
    Journal articles | 2018
    Papachristou EK; Kishore K; Holding AN; Harvey K; Roumeliotis TI; Chilamakuri CSR; Omarjee S; Chia KM; Swarbrick A; Lim E; Markowetz F; Eldridge M; Siersbaek R; D’Santos CS; Carroll JS, 2018, 'A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes', Nature Communications, 9, http://dx.doi.org/10.1038/s41467-018-04619-5
    Journal articles | 2018
    Rogers S; McCloy RA; Parker BL; Gallego-Ortega D; Law AMK; Chin VT; Conway JRW; Fey D; Millar EKA; O’Toole S; Deng N; Swarbrick A; Chastain PD; Cesare AJ; Timpson P; Caldon CE; Croucher DR; James DE; Watkins DN; Burgess A, 2018, 'MASTL overexpression promotes chromosome instability and metastasis in breast cancer', Oncogene, 37, pp. 4518 - 4533, http://dx.doi.org/10.1038/s41388-018-0295-z
    Journal articles | 2018
    Singh M; Al-Eryani G; Carswell S; Ferguson J; Blackburn J; Barton K; Roden D; Luciani F; Phan T; Junankar S; Jackson K; Goodnow C; Smith M; Swarbrick A, 2018, 'High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes', , http://dx.doi.org/10.1101/424945
    Journal articles | 2018
    Wirasinha RC; Vijayan D; Smith NJ; Parnell GP; Swarbrick A; Brink R; King C; Stewart G; Booth DR; Batten M, 2018, 'GPR65 inhibits experimental autoimmune encephalomyelitis through CD4+ T cell independent mechanisms that include effects on iNKT cells', Immunology and Cell Biology, 96, pp. 128 - 136, http://dx.doi.org/10.1111/imcb.1031
    Journal articles | 2017
    Lin HM; Mahon KL; Spielman C; Gurney H; Mallesara G; Stockler MR; Bastick P; Briscoe K; Marx G; Swarbrick A; Horvath LG, 2017, 'Phase 2 study of circulating microRNA biomarkers in castration-resistant prostate cancer', British Journal of Cancer, 116, pp. 1002 - 1011, http://dx.doi.org/10.1038/bjc.2017.50
    Journal articles | 2017
    Nikolic I; Elsworth B; Dodson E; Wu SZ; Gould CM; Mestdagh P; Marshall GM; Horvath LG; Simpson KJ; Swarbrick A, 2017, 'Discovering cancer vulnerabilities using high-throughput micro-RNA screening', Nucleic Acids Research, 45, pp. 12657 - 12670, http://dx.doi.org/10.1093/nar/gkx1072
    Journal articles | 2017
    Rojo F; Ruiz Borrego M; Hui M; Trigo Perez JM; Cazet A; Karsdal MA; Urruticoechea A; Antolin S; García-Saenz JA; O’Toole S; Blach A; Perez-Ramos L; Bezares S; Sánchez-Aragó M; Caballero R; Bager CL; Swarbrick A; Martin Jimenez M, 2017, 'Tumor microenvironment biomarkers as therapeutic strategies for TNBC', Annals of Oncology, 28, pp. v597 - v597, http://dx.doi.org/10.1093/annonc/mdx391.004
    Journal articles | 2017
    Weinberg F; Reischmann N; Fauth L; Taromi S; Mastroianni J; Köhler M; Halbach S; Becker AC; Deng N; Schmitz T; Uhl FM; Herbener N; Riedel B; Beier F; Swarbrick A; Lassmann S; Dengjel J; Zeiser R; Brummer T, 2017, 'The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior', EBioMedicine, 20, pp. 79 - 97, http://dx.doi.org/10.1016/j.ebiom.2017.04.015
    Journal articles | 2016
    Baker LA; Holliday H; Swarbrick A, 2016, 'ID4 controls luminal lineage commitment in normal mammary epithelium and inhibits BRCA1 function in basal-like breast cancer', Endocrine-Related Cancer, 23, pp. R381 - R392, http://dx.doi.org/10.1530/ERC-16-0196
    Journal articles | 2016
    Beckers RK; Selinger C; Vilain R; Madore J; Wilmott JS; Harvey K; Holliday A; Cooper CL; Robbins E; Gillet D; Kennedy CW; Gluch L; Carmalt H; Mak C; Warrier S; Gee HE; Chan C; McLean A; Walker E; McNeil CM; Beith JM; Swarbrick A; Scolyer RA; O'Toole SA, 2016, 'PDl1 expression in triple-negative breast cancer is associated with tumour-infiltrating lymphocytes and improved outcome.', Pathology, 48 Suppl 1, pp. S146 - S147, http://dx.doi.org/10.1016/j.pathol.2015.12.399
    Journal articles | 2016
    Beckers RK; Selinger CI; Vilain R; Madore J; Wilmott JS; Harvey K; Holliday A; Cooper CL; Robbins E; Gillett D; Kennedy CW; Gluch L; Carmalt H; Mak C; Warrier S; Gee HE; Chan C; McLean A; Walker E; McNeil CM; Beith JM; Swarbrick A; Scolyer RA; O'Toole SA, 2016, 'Programmed death ligand 1 expression in triple-negative breast cancer is associated with tumour-infiltrating lymphocytes and improved outcome', Histopathology, 69, pp. 25 - 34, http://dx.doi.org/10.1111/his.12904
    Journal articles | 2016
    Sax MJ; Gasch C; Athota VR; Freeman R; Rasighaemi P; Westcott DE; Day CJ; Nikolic I; Elsworth B; Wei M; Rogers K; Swarbrick A; Mittal V; Pouliot N; Mellick AS, 2016, 'Cancer cell CCL5 mediates bone marrow independent angiogenesis in breast cancer', Oncotarget, 7, pp. 85437 - 85449, http://dx.doi.org/10.18632/oncotarget.13387
    Journal articles | 2015
    Gallego-Ortega D; Ledger A; Roden DL; Law AMK; Magenau A; Kikhtyak Z; Cho C; Allerdice SL; Lee HJ; Valdes-Mora F; Herrmann D; Salomon R; Young AIJ; Lee BY; Sergio CM; Kaplan W; Piggin C; Conway JRW; Rabinovich B; Millar EKA; Oakes SR; Chtanova T; Swarbrick A; Naylor MJ; O’Toole S; Green AR; Timpson P; Gee JMW; Ellis IO; Clark SJ; Ormandy CJ, 2015, 'ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells', PLoS Biology, 13, http://dx.doi.org/10.1371/journal.pbio.1002330
    Journal articles | 2015
    Gee HE; Buffa FM; Harris AL; Toohey JM; Carroll SL; Cooper CL; Beith J; McNeil C; Carmalt H; Mak C; Warrier S; Holliday A; Selinger C; Beckers R; Kennedy C; Graham P; Swarbrick A; Millar EKA; O'Toole SA; Molloy T, 2015, 'MicroRNA-related DNA repair/cell-cycle genes independently associated with relapse after radiation therapy for early breast cancer', International Journal of Radiation Oncology Biology Physics, 93, pp. 1104 - 1114, http://dx.doi.org/10.1016/j.ijrobp.2015.08.046
    Journal articles | 2015
    Hui M; Cazet A; Jessica Y; Cooper C; McFarland A; Nair R; O'Toole S; Swarbrick A, 2015, 'Targeting the hedgehog signalling pathway in triple negative breast cancer', Annals of Oncology, 26, pp. iii31, http://dx.doi.org/10.1093/annonc/mdv121.02
    Journal articles | 2015
    Junankar S; Baker LA; Roden DL; Nair R; Elsworth B; Gallego-Ortega D; Lacaze P; Cazet A; Nikolic I; Teo WS; Yang J; McFarland A; Harvey K; Naylor MJ; Lakhani SR; Simpson PT; Raghavendra A; Saunus J; Madore J; Kaplan W; Ormandy C; Millar EKA; O'Toole S; Yun K; Swarbrick A, 2015, 'ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype', NATURE COMMUNICATIONS, 6, http://dx.doi.org/10.1038/ncomms7548
    Journal articles | 2015
    Junankar S; Baker LA; Roden DL; Nair R; Elsworth B; Gallego-Ortega D; Lacaze P; Cazet A; Nikolic I; Teo WS; Yang J; McFarland A; Harvey K; Naylor MJ; Lakhani SR; Simpson PT; Raghavendra A; Saunus J; Madore J; Kaplan W; Ormandy C; Millar EKA; O'Toole S; Yun K; Swarbrick A, 2015, 'ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype', Nature Communications, 6, http://dx.doi.org/10.1038/ncomms7548
    Journal articles | 2015
    Junankar S; Shay G; Jurczyluk J; Ali N; Down J; Pocock N; Parker A; Nguyen A; Sun S; Kashemirov B; McKenna CE; Croucher PI; Swarbrick A; Weilbaecher K; Phan TG; Rogers MJ, 2015, 'Real-Time Intravital Imaging Establishes Tumor-Associated Macrophages as the Extraskeletal Target of Bisphosphonate Action in Cancer', Cancer Discovery, 5, pp. 35 - 42, http://dx.doi.org/10.1158/2159-8290.CD-14-0621
    Journal articles | 2015
    Liu PY; Erriquez D; Marshall GM; Tee AE; Polly P; Wong M; Liu B; Bell JL; Zhang XD; Milazzo G; Cheung BB; Fox A; Swarbrick A; Hüttelmaier S; Kavallaris M; Perini G; Mattick JS; Dinger ME; Liu T, 2015, 'Erratum: Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression (Journal of the National Cancer Institute (2014) 106:7 (dju113) DOI: 10.1093/jnci/dju113)', Journal of the National Cancer Institute, 107, http://dx.doi.org/10.1093/jnci/dju359
    Journal articles | 2015
    Phua YW; Nguyen A; Roden DL; Elsworth B; Deng N; Nikolic I; Yang J; Mcfarland A; Russell R; Kaplan W; Cowley MJ; Nair R; Zotenko E; O'Toole S; Tan SX; James DE; Clark SJ; Kouros-Mehr H; Swarbrick A, 2015, 'MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene', Breast Cancer Research, http://dx.doi.org/10.1186/s13058-015-0593-0
    Journal articles | 2014
    Ali NA; Wu J; Hochgräfe F; Chan H; Nair R; Ye S; Zhang L; Lyons RJ; Pinese M; Lee HC; Armstrong N; Ormandy CJ; Clark SJ; Swarbrick A; Daly RJ, 2014, 'Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways', Breast Cancer Research, 16, http://dx.doi.org/10.1186/s13058-014-0437-3
    Journal articles | 2014
    Lin HM; Castillo L; Mahon KL; Chiam K; Lee BY; Nguyen Q; Boyer MJ; Stockler MR; Pavlakis N; Marx G; Mallesara G; Gurney H; Clark SJ; Swarbrick A; Daly RJ; Horvath LG, 2014, 'Circulating microRNAs are associated with docetaxel chemotherapy outcome in castration-resistant prostate cancer', British Journal of Cancer, 110, pp. 2462 - 2471, http://dx.doi.org/10.1038/bjc.2014.181
    Journal articles | 2014
    Liu PY; Erriquez D; Marshall GM; Tee AE; Polly P; Wong M; Liu B; Bell JL; Zhang XD; Milazzo G; Cheung BB; Fox A; Swarbrick A; Hüttelmaier S; Kavallaris M; Perini G; Mattick JS; Dinger ME; Liu T, 2014, 'Effects of a Novel Long Noncoding RNA, lncUSMycN, on N-Myc Expression and Neuroblastoma Progression', Journal of the National Cancer Institute, 106, pp. dju113, http://dx.doi.org/10.1093/jnci/dju113
    Journal articles | 2014
    Nair R; Teo WS; Mittal V; Swarbrick A, 2014, 'ID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities', Molecular Therapy, 22, pp. 1407 - 1415, http://dx.doi.org/10.1038/mt.2014.83
    Journal articles | 2014
    Owens TW; Rogers RL; Best SA; Ledger A; Mooney AM; Ferguson A; Shore P; Swarbrick A; Ormandy CJ; Simpson PT; Carroll JS; Visvader JE; Naylor MJ, 2014, 'Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer', Cancer Research, 74, pp. 5277 - 5286, http://dx.doi.org/10.1158/0008-5472.CAN-14-0053
    Journal articles | 2014
    Selinger CI; Beckers R; Tran T; Cooper W; Harvey K; Swarbrick A; O’Toole S, 2014, 'MET Copy number in triple negative breast cancers', Pathology, 46, pp. S80 - S81, http://dx.doi.org/10.1097/01.pat.0000443613.80012.22
    Journal articles | 2014
    Teo WS; Nair R; Swarbrick A, 2014, 'New insights into the role of ID proteins in breast cancer metastasis: A MET affair', Breast Cancer Research, 16, http://dx.doi.org/10.1186/bcr3654
    Journal articles | 2013
    Al-Ejeh F; Shi W; Miranda M; Simpson PT; Vargas AC; Song S; Wiegmans AP; Swarbrick A; Welm AL; Brown MP; Chenevix-Trench G; Lakhani SR; Khanna KK, 2013, 'Treatment of triple-negative breast cancer using anti-EGFR-directed radioimmunotherapy combined with radiosensitizing chemotherapy and PARP inhibitor', Journal of Nuclear Medicine, 54, pp. 913 - 921, http://dx.doi.org/10.2967/jnumed.112.111534
    Journal articles | 2013
    Croucher DR; Hochgräfe F; Zhang L; Liu L; Lyons RJ; Rickwood D; Tactacan CM; Browne BC; Ali N; Chan H; Shearer R; Gallego-Ortega D; Saunders DN; Swarbrick A; Daly RJ, 2013, 'Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway', Cancer Research, 73, pp. 1969 - 1980, http://dx.doi.org/10.1158/0008-5472.CAN-12-1472
    Journal articles | 2013
    Hui M; Cazet A; Nair R; Watkins DN; O'Toole SA; Swarbrick A, 2013, 'The Hedgehog signalling pathway in breast development, carcinogenesis and cancer therapy', Breast Cancer Research, 15, http://dx.doi.org/10.1186/bcr3401
    Journal articles | 2013
    Koese M; Rentero C; Kota BP; Hoque M; Cairns R; Wood P; Vilà De Muga S; Reverter M; Alvarez-Guaita A; Monastyrskaya K; Hughes WE; Swarbrick A; Tebar F; Daly RJ; Enrich C; Grewal T, 2013, 'Annexin A6 is a scaffold for PKCα to promote EGFR inactivation', Oncogene, 32, pp. 2858 - 2872, http://dx.doi.org/10.1038/onc.2012.303
    Journal articles | 2013
    Lee P; Ho KKY; Swarbrick A, 2013, 'Brown Adipose Tissue in Adult Humans: A Metabolic Renaissance', Endocrine Reviews, 34, pp. 413 - 438, http://dx.doi.org/10.1210/er.2012-1081
    Journal articles | 2013
    Nair R; Roden DL; Teo WS; McFarland A; Junankar S; Ye S; Nguyen A; Yang J; Nikolic I; Hui M; Morey A; Shah J; Pfefferle AD; Usary J; Selinger C; Baker LA; Armstrong N; Cowley MJ; Naylor MJ; Ormandy CJ; Lakhani SR; Herschkowitz JI; Perou CM; Kaplan W; O'Toole SA; Swarbrick A, 2013, 'c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer', Oncogene, http://dx.doi.org/10.1038/onc.2013.368
    Journal articles | 2013
    Natividad KDT; Junankar S; Mohd redzwan N; Wirasinha RC; King C; Brink R; Swarbrick A; Batten ML; Nair R, 2013, 'Interleukin-27 Signaling Promotes Immunity against Endogenously Arising Murine Tumors', PLoS ONE, 8, pp. e57469, http://dx.doi.org/10.1371/journal.pone.0057469
    Journal articles | 2013
    O'Toole S; Beith JM; Millar EKA; West R; McLean A; Cazet A; Swarbrick A; Oakes , 2013, 'Therapeutic targets in triple negative breast cancer', Journal of Clinical Pathology, 66, pp. 530 - 542, http://dx.doi.org/10.1136/jclinpath-2012-201361
    Journal articles | 2013
    Plummer PN; Freeman R; Taft RJ; Vider J; Sax M; Umer BA; Gao D; Johns C; Mattick JS; Wilton SD; Ferro V; McMillan NAJ; Swarbrick A; Mittal V; Mellick AS, 2013, 'MicroRNAs regulate tumor angiogenesis modulated by endothelial progenitor cells', Cancer Research, 73, pp. 341 - 352, http://dx.doi.org/10.1158/0008-5472.CAN-12-0271
    Journal articles | 2013
    Swarbrick A; Junankar SR; Batten M, 2013, 'Could the properties of IL-27 make it an ideal adjuvant for anticancer immunotherapy', OncoImmunology, 2, http://dx.doi.org/10.4161/onci.25409
    Journal articles | 2013
    Warrier S; Sellinger C; Beith JM; Cazet A; Swarbrick A; Carmalt H; O'Toole S, 2013, 'Claudin-1 as a novel transcriptional target of hedgehog signaling and a predictor for outcome in breast cancer.', Journal of Clinical Oncology, 31, pp. 1053 - 1053, http://dx.doi.org/10.1200/jco.2013.31.15_suppl.1053
    Journal articles | 2012
    Kalyuga M; Gallego-Ortega D; Lee H; Roden DL; Cowley MJ; Caldon CE; Stone A; Allerdice SL; Valdes-Mora F; Rosalind launchbury R; Statham A; Armstrong NJ; Alles MC; Adelaide young A; Egger A; Au W; Piggin CL; Evans C; Ledger A; Brummer T; Oakes SR; Kaplan W; Gee JMW; Robert i nicholson RI; Sutherland RL; Swarbrick A; Naylor MJ; Clark SJ; Carroll JS; Ormandy CJ, 2012, 'ELF5 Suppresses Estrogen Sensitivity and Underpins the Acquisition of Antiestrogen Resistance in Luminal Breast Cancer', PLoS Biology, 10, pp. e1001461, http://dx.doi.org/10.1371/journal.pbio.1001461
    Journal articles | 2012
    McFarland A; Phua Y; Swarbrick A; Nair R, 2012, 'Meeting The 3Rs with the Use of In Vivo Imaging', JOURNAL OF THE AMERICAN ASSOCIATION FOR LABORATORY ANIMAL SCIENCE, 51, pp. 687 - 688, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000313303300243&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2012
    O’Toole S; Machakel D; Millar E; Nair R; Cooper C; Qiu MR; McLeod D; Sutherland R; Watkins N; Swarbrick A, 2012, '35. Hedgehog overexpression is regulated by stromal interactions and predicts for poor outcome in invasive ductal carcinoma', Pathology, 44, pp. S114 - S114, http://dx.doi.org/10.1016/s0031-3025(16)32927-0
    Journal articles | 2012
    Swarbrick A; Daly RJ, 2012, 'New insights into signalling networks regulating breast cancer stem cells', Breast Cancer Research, 14, pp. 321, http://dx.doi.org/10.1186/bcr3209
    Journal articles | 2010
    O'Toole SA; Machalek D; Shearer R; Millar EKA; Nair R; Martelotto L; McLeod D; Cooper C; Qiu MR; Sutherland RL; Watkins DN; Swarbrick A, 2010, 'Hedgehog Ligand Overexpression Predicts Poor Outcome in Breast Cancer and Is a Potential Therapeutic Target for Metastatic Disease', CANCER RESEARCH, 70, http://dx.doi.org/10.1158/0008-5472.SABCS10-S6-8
    Journal articles | 2009
    O Toole S; Swarbrick A; Sutherland RL, 2009, 'The Hedgehog signalling pathway as a therapeutic target in early breast cancer development', Expert Opinion on Therapeutic Targets, 13, pp. 1095 - 1103
    Journal articles | 2008
    Butt A; Caldon CE; Mcneil CM; Swarbrick A; Musgrove EA; Sutherland RL, 2008, 'Cell cycle machinery: Links with genesis and treatment of breast cancer', Advances in Experimental Medicine and Biology, 630, pp. 189 - 205
    Journal articles | 2008
    Caldon CE; Swarbrick A; Lee CS; Sutherland RL; Musgrove EA, 2008, 'The helix-loop-helix protein Id1 requires cyclin D1 to promote the proliferation of mammary epithelial cell acini', Cancer research, 68, pp. 3026 - 3036, http://dx.doi.org/10.1158/0008-5472.CAN-07-3079
    Journal articles | 2008
    Swarbrick A, 2008, 'Review of: Tumour invasion and metastasis initiated by microRNA-10b in breast cancer', Breast Cancer Online, 11, http://dx.doi.org/10.1017/S1470903108006688
    Journal articles | 2005
    Kairouz R; Parmar J; Lyons RJ; Swarbrick A; Musgrove EA; Daly RJ, 2005, 'Hormonal regulation of the grb14 signal modulator and its role in cellcycle progression of MCF-7 human breast cancer cells', Journal of Cellular Physiology, 203, pp. 85 - 93
    Journal articles | 2005
    Swarbrick A; Akerfeldt M; Lee CS; Sergio CM; Caldon CE; Hunter LJ; Sutherland RL; Musgrove EA; Lee CS, 2005, 'Regulation of cyclin expression and cell cycle progression in breastepithelial cells by the helix-loop-helix protein Id1', Oncogene, 24, pp. 381 - 389, http://dx.doi.org/10.1038/sj.onc.1208188
    Journal articles | 2003
    Carroll JS; Lynch DK; Swarbrick A; Renoir J; Sarcevic B; Daly RJ; Musgrove EA; Sutherland RL, 2003, 'p27Kip1 induces quiescence and growth factor insensitivity in tamoxifen-treated breast cancer cells', Cancer research, 63, pp. 4322 - 4326
    Journal articles | 2003
    Carroll JS; Lynch DK; Swarbrick A; Renoir JM; Sarcevic B; Daly RJ; Musgrove EA; Sutherland RL, 2003, 'p27Kip1 induces quiescence and growth factor insensitivity in tamoxifen-treated breast cancer cells', Cancer Research, 63, pp. 4322 - 4326
    Journal articles | 2003
    Sutherland RL; Carroll JS; Sergio CM; Swarbrick A; Musgrove EA, 2003, '97. Steroid regulation of breast cancer cell proliferation', Reproduction, Fertility and Development, 15, pp. 97 - 97, http://dx.doi.org/10.1071/srb03ab97
    Journal articles | 2002
    Carroll JS; Swarbrick A; Musgrove EA; Sutherland RL, 2002, 'Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: Implications for the antiproliferative effects of antiestrogens', Cancer Research, 62, pp. 3126 - 3131
    Journal articles | 2001
    Wei M; Cohen SM; Silverman AP; Lippard SJ, 2001, 'Effects of spectator ligands on the specific recognition of intrastrand platinum-DNA cross-links by high mobility group box and TATA-binding proteins.', J Biol Chem, 276, pp. 38774 - 38780, http://dx.doi.org/10.1074/jbc.M106374200
    Journal articles | 2000
    Swarbrick A; Lee CSL; Sutherland RL; Musgrove EA, 2000, 'Cooperation of p27(Kip1) and p18(INK4c) in progestin-mediated cell cycle arrest in T-47D breast cancer cells', Molecular and Cellular Biology, 20, pp. 2581 - 2591, http://dx.doi.org/10.1128/MCB.20.7.2581-2591.2000
    Journal articles | 1997
    Swarbrick A; Lim RL; Upcroft JA; Stewart TS, 1997, 'Nucleotide variation in the cytidine triphosphate synthetase gene of Giardia duodenalis', Journal of Eukaryotic Microbiology, 44, pp. 531 - 534
    Journal articles | 1997
    Swarbrick A; Murby EJ; Hume P, 1997, 'Post-column electrochemical oxidation of leuco malachite green for the analysis of rainbow trout flesh using HPLC with absorbance detection', Journal of Liquid Chromatography and Related Technologies, 20, pp. 2269 - 2280, http://dx.doi.org/10.1080/10826079708006562
  • Preprints | 2024
    Apostolov E; Roden DL; Holliday H; Cazet A; Harvey K; Zhang H; Wu SZ; van der Leij S; Selth LA; Bartonicek N; Al-Eryani G; He M; Lundeberg J; Reeves J; Kench JG; Potter AJ; Stricker P; Joshua AM; Horvath L; Swarbrick A, 2024, Profiling of epithelial functional states and fibroblast phenotypes in hormone therapy-naïve localised prostate cancer, http://dx.doi.org/10.1101/2024.10.23.619925
    Preprints | 2024
    Cai Z; Boys EL; Noor Z; Aref A; Xavier D; Lucas N; Williams SG; Koh JMS; Poulos RC; Wu Y; Dausmann M; MacKenzie KL; Aguilar-Mahecha A; Armengol C; Barranco MM; Basik M; Bowman ED; Clifton-Bligh RJ; Connolly EA; Cooper WA; Dalal B; DeFazio A; Filipits M; Flynn PJ; Graham JD; George J; Gill AJ; Gnant M; Habib R; Harris CC; Harvey K; Horvath LG; Jackson C; Kohonen-Corish MRJ; Lim E; Liu J; Long G; Lord RV; Mann GJ; McCaughan GW; Morgan L; Murphy LC; Nagabushan S; Nagrial AM; Navinés J; Panizza BJ; Samra JS; Scolyer RA; Souglakos I; Swarbrick A; Thomas DM; Balleine RL; Hains PG; Robinson PJ; Zhong Q; Reddel RR, 2024, Federated deep learning enables cancer subtyping by proteomics, http://dx.doi.org/10.1101/2024.10.16.618763
    Preprints | 2024
    Parsons A; Colon ES; Spasic M; Kurt BB; Swarbrick A; Freedman RA; Mittendorf EA; van Galen P; McAllister SS, 2024, Cell Populations in Human Breast Cancers are Molecularly and Biologically Distinct with Age., http://dx.doi.org/10.21203/rs.3.rs-5167339/v1
    Conference Papers | 2024
    Sandarenu P; Chen J; Slapetova I; Browne L; Graham PH; Swarbrick A; Millar EKA; Song Y; Meijering E, 2024, 'Semi-Supervised Variational Autoencoder for Cell Feature Extraction In Multiplexed Immunofluorescence Images', in Proceedings - International Symposium on Biomedical Imaging, http://dx.doi.org/10.1109/ISBI56570.2024.10635107
    Preprints | 2023
    Wang T; Harvey K; Morlanes JE; Kiedik B; Al-Eryani G; Greenwald A; Kalavros N; Dezem FS; Ma Y; Pita-Juarez YH; Wise K; Degletagne C; Elz A; Hadadianpour A; Johanneson J; Pakiam F; Ryu H; Newell EW; Tonon L; Kohlway A; Drennon T; Abousoud J; Stott R; Lund P; Durruthy J; Vallejo AF; Kaczorowski D; Warren J; Butler LM; O’Toole S; Plummer J; Vlachos IS; Lundeberg J; Swarbrick A; Martelotto L, 2023, snPATHO-seq: unlocking the pathology archives, http://dx.doi.org/10.1101/2023.12.07.570700
    Preprints | 2023
    Wang T; Harvey K; Reeves J; Roden DL; Bartonicek N; Yang J; Al-Eryani G; Kaczorowski D; Chan C-L; Powell J; O’Toole S; Lim E; Swarbrick A, 2023, An experimental comparison of the Digital Spatial Profiling and Visium spatial transcriptomics technologies for cancer research, http://dx.doi.org/10.1101/2023.04.06.535805
    Preprints | 2022
    Al-Eryani G; Bartonicek N; Chan C-L; Anderson A; Harvey K; Wu SZ; Roden D; Wang T; Reeves J; Yeung BZ; Masle-Farquhar E; Goodnow CC; Ma C; Phan TG; Lundeberg J; Junankar S; Swarbrick A, 2022, Integration of single-cell RNA and protein data identifies novel clinically-relevant lymphocyte phenotypes in breast cancers, http://dx.doi.org/10.1101/2022.05.31.494081
    Conference Posters | 2022
    Baldwin LA; Bartonicek N; Yang J; Wu SZ; Deng N; Roden D; Chan C-L; Al-Eryani G; Zanker DJ; Parker BS; Swarbrick A; Junankar S, 2022, 'Dna barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and in response to immunotherapy', Vol. 82, http://dx.doi.org/10.1158/1538-7445.SABCS21-P1-04-04
    Preprints | 2022
    Chaudagar K; Hieromnimon HM; Khurana R; Labadie B; Hirz T; Mei S; Hasan R; Shafran J; Kelley A; Apostolov E; Al-Eryani G; Harvey K; Rameshbabu S; Loyd M; Bynoe K; Drovetsky C; Solanki A; Markiewicz E; Zamora M; Fan X; Schürer S; Swarbrick A; Sykes DB; Patnaik A, 2022, Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer, http://dx.doi.org/10.1101/2022.05.12.490223
    Preprints | 2022
    Masle-Farquhar E; Jackson KJL; Peters T; Al-Eryani G; Singh M; Payne K; Rao G; Apps G; Kingham J; Jara C; Skvortsova K; Swarbrick A; Ma C; Suan D; Uzel G; Chua I; Leiding J; Heiskanen K; Preece K; Kainulainen L; O’Sullivan M; Cooper M; Seppänen MRJ; Mustjoki S; Brothers S; Vogel T; Brink R; Tangye S; Reed J; Goodnow C, 2022, STAT3gain-of-function mutations connect leukemia with autoimmune disease by pathological dysregulation of NKG2DhiCD8 killer T cells, http://dx.doi.org/10.1101/2022.02.11.480027
    Conference Abstracts | 2022
    Strach MC; Yeung N; Apostolov E; Lin H-M; Nagaraju RT; Ansari N; Koh C; Shin J-S; Kench J; Aziz O; Swarbrick A; Horvath LG; Barriuso J; Mahon K, 2022, 'Single-cell transcriptomic analysis of appendiceal cancer peritoneal disease', in ANNALS OF ONCOLOGY, ELSEVIER, ELECTR NETWORK, Vol. 33, pp. S1322 - S1322, presented at Annual Meeting of the European-Society-for-Medical-Oncology (ESMO), ELECTR NETWORK, 09 September 2022 - 13 September 2022, http://dx.doi.org/10.1016/j.annonc.2022.07.1791
    Preprints | 2022
    Vallejo A; Harvey K; Wang T; Wise K; Butler L; Polo J; Plummer J; Swarbrick A; Martelotto L, 2022, snPATHO-seq: unlocking the FFPE archives for single nucleus RNA profiling, http://dx.doi.org/10.1101/2022.08.23.505054
    Preprints | 2021
    Deng N; Minoche A; Harvey K; Li M; Winkler J; Goga A; Swarbrick A, 2021, Deep Whole Genome Sequencing Identifies Recurrent Genomic Alterations in Commonly-Used Breast Cancer Cell Lines and Patient Derived Xenograft Models, http://dx.doi.org/10.21203/rs.3.rs-859624/v2
    Conference Papers | 2021
    Portman N; Milioli H; Alexandrou S; Coulson R; Yong A; Fernandez K; Chia K; Halilovic E; Segara D; Parker A; Haupt S; Haupt Y; Tilley W; Swarbrick A; Caldon L; Lim E, 2021, 'Abstract PS18-17: Mdm2 inhibition synergises with endocrine therapy or cdk4/6 inhibition for the treatment of estrogen receptor-positive breast cancer', in Cancer Research, American Association for Cancer Research (AACR), presented at Abstracts: 2020 San Antonio Breast Cancer Virtual Symposium; December 8-11, 2020; San Antonio, Texas, http://dx.doi.org/10.1158/1538-7445.sabcs20-ps18-17
    Conference Abstracts | 2021
    Portman N; Milioli H; Alexandrou S; Coulson R; Yong A; Fernandez K; Chia K; Halilovic E; Segara D; Parker A; Haupt S; Haupt Y; Tilley W; Swarbrick A; Caldon L; Lim E, 2021, 'Mdm2 inhibition synergises with endocrine therapy or cdk4/6 inhibition for the treatment of estrogen receptor-positive breast cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 81, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000618737700638&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2021
    Quek C; Silva IP; Al-Eryani G; Mayer A; Bartonicek N; Harvey K; Buckley C; Braubach O; Thompson JF; Stretch JR; Saw RPM; Shannon KF; Menzies AM; Scolyer RA; Long GV; Swarbrick A; Wilmott JS, 2021, 'Abstract 2761: CODEX highly multiplex image mapping to CITEseq datasets reveal the spatial dynamics of the TME during the development of acquired resistant in immunotherapy treated melanoma', in Cancer Research, American Association for Cancer Research (AACR), pp. 2761 - 2761, http://dx.doi.org/10.1158/1538-7445.am2021-2761
    Conference Abstracts | 2021
    Quek C; Silva IP; Al-Eryani G; Mayer A; Bartonicek N; Harvey K; Buckley C; Braubach O; Thompson JF; Stretch JR; Saw RPM; Shannon KF; Menzies AM; Scolyer RA; Long GV; Swarbrick A; Wilmott JS, 2021, 'CODEX highly multiplex image mapping to CITEseq datasets reveal the spatial dynamics of the TME during the development of acquired resistant in immunotherapy treated melanoma.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 81, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000680263504311&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2021
    Wu SZ; Roden D; Al Eryani G; Junankar S; Lim E; Thennavan A; Andersson A; Williams S; Gong J; Fropf R; Fuhrman K; Lundeberg J; Perou C; Swarbrick A, 2021, 'An integrated multi-omic cellular atlas of human breast cancers.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 81, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000680263502037&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2021
    Wu SZ; Roden D; Eryani GA; Junankar S; Lim E; Thennavan A; Andersson A; Williams S; Gong J; Fropf R; Fuhrman K; Lundeberg J; Perou C; Swarbrick A, 2021, 'Abstract 129: An integrated multi-omic cellular atlas of human breast cancers', in Cancer Research, American Association for Cancer Research (AACR), pp. 129 - 129, http://dx.doi.org/10.1158/1538-7445.am2021-129
    Preprints | 2020
    Baker LA; Holliday H; Roden D; Krisp C; Wu SZ; Junankar S; Serandour AA; Mohammed H; Nair R; Sankaranarayanan G; Law AMK; McFarland A; Simpson PT; Lakhani S; Dodson E; Selinger C; Anderson L; Samimi G; Hacker NF; Lim E; Ormandy CJ; Naylor MJ; Simpson K; Nikolic I; O’Toole S; Kaplan W; Cowley MJ; Carroll JS; Molloy M; Swarbrick A, 2020, Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer, http://dx.doi.org/10.21203/rs.3.rs-16182/v1
    Preprints | 2020
    Baker LA; Holliday H; Roden D; Krisp C; Wu SZ; Junankar S; Serandour AA; Mohammed H; Nair R; Sankaranarayanan G; Law AMK; McFarland A; Simpson PT; Lakhani S; Dodson E; Selinger C; Anderson L; Samimi G; Hacker NF; Lim E; Ormandy CJ; Naylor MJ; Simpson K; Nikolic I; O’Toole S; Kaplan W; Cowley MJ; Carroll JS; Molloy M; Swarbrick A, 2020, Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer, http://dx.doi.org/10.21203/rs.3.rs-16182/v2
    Conference Abstracts | 2020
    Hickey T; Selth L; Chia KM; Milioli HH; Laven-Law G; Roden D; Jindal S; Hui M; Ebrahimie E; Birrel SN; Stello S; Iggo R; Alexandrou S; Caldon L; Finlay-Shultz J; Abdel-Fatah TM; Ellis IO; Zwart W; Palmieri C; Sartorious CA; Swarbrick A; Lim E; Carrol JS; Tilley WD, 2020, 'The androgen receptor is a tumour suppressor in estrogen receptor positive breast cancer', in Journal of the Endocrine Society, Oxford University Press (OUP), Vol. 4, pp. or05 - or06, presented at Endocrine Society Annual Meeting, http://dx.doi.org/10.1210/jendso/bvaa046.982
    Conference Papers | 2020
    Lim E; Milioli HH; Alexandrou S; Coulson R; Yong A; Fernandez KJ; Chia K; Halilovic E; Segara D; Parker A; Haupt S; Haupt Y; Tilley WD; Swarbrick A; Caldon EC; Portman N, 2020, 'MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 110 - 110, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000790145400122&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints | 2020
    Tilley W; Hickey T; Selth L; Chia KM; Milioli H; Laven-Law G; Roden D; Jindal S; Hui M; Finlay-Schultz J; Ebrahimie E; Birrell S; Stelloo S; Iggo R; Alexandrou S; Caldon C; Abdel-Fatah T; Ellis I; Zwart W; Palmieri C; Sartorius C; Swarbrick A; Lim E; Carroll J, 2020, The Androgen Receptor is a Tumour Suppressor in Estrogen Receptor Positive Breast Cancer, http://dx.doi.org/10.21203/rs.3.rs-62718/v1
    Conference Abstracts | 2019
    Al-Eryani G; Singh M; Wu S; Carswell S; Jackson K; Junankar S; Bartonicek N; Luciani F; Phan T; Smith M; Goodnow CC; Swarbrick A; Roden D, 2019, 'Linking multi-modal single-cell RNA sequencing with targeted long-read sequencing reveals the clonal and transcriptional profile of lymphocytes', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY, PEOPLES R CHINA, Beijing, Vol. 49, pp. 1343 - 1343, presented at 17th International Congress of Immunology of the International-Union-of-Immunological-Societies (IUIS), PEOPLES R CHINA, Beijing, 19 October 2019 - 23 October 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000490026904252&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Chia KM; Milioli HH; Portman N; Laven-Law G; Coulson R; Young A; Segara D; Parker A; Caldon L; Deng N; Swarbrick A; Tilley W; Hickey T; Lim E, 2019, 'Targeting AR in endocrine-resistant breast cancer', in Oncolabs, Bioscientifica, presented at 7th PacRim Breast & Prostate Cancer Meeting, http://dx.doi.org/10.1530/oncolabs.1.P012
    Conference Abstracts | 2019
    Chin VT; Al Eryani G; McCloy R; Stone E; Havryk A; Plit M; Field A; Watkins N; Swarbrick A; Powell J, 2019, 'Using single cell genomics to change the treatment of lung cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, Vol. 37, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2019 - 04 June 2019, http://dx.doi.org/10.1200/JCO.2019.37.15_suppl.e20563
    Conference Abstracts | 2019
    Lim E; Hickey TA; Selth LA; Chia KM; Milioli HH; Roden D; Laven-Law G; Jindal S; Hui M; Ebrahimie E; Birrell SN; Stelloo S; Caldon CE; Finlay-Schultz J; Abdel-Fatah TM; Ellis IO; Zwart W; Palmieri C; Sartorius CA; Swarbrick A; Carroll JS; Tilley WD, 2019, 'The androgen receptor is a tumour suppressor in estrogen receptor positive breast cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, TX, San Antonio, Vol. 80, presented at 42nd Annual San Antonio Breast Cancer Symposium, TX, San Antonio, 09 December 2019 - 14 December 2019, http://dx.doi.org/10.1158/1538-7445.SABCS19-GS2-03
    Preprints | 2019
    Murali R; Varghese BA; Karthikeyan N; Archana PT; Teo WS; McFarland A; Roden DL; Holliday H; Konrad C; Cazet A; Dodson E; George JT; Levine H; Jolly MK; Swarbrick A; Nair R, 2019, Targeting the Id1-Kif11-Aurka axis in triple negative breast cancer using combination therapy, http://dx.doi.org/10.1101/760686
    Conference Abstracts | 2018
    Chia KM; Milioli H; Portman N; Laven-Law G; Yong A; Swarbrick A; Caldon L; Tilley W; Hickey T; Lim E, 2018, 'Activation of AR inhibits growth of endocrine-resistant breast cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, TX, San Antonio, Vol. 79, presented at San Antonio Breast Cancer Symposium, TX, San Antonio, 04 December 2018 - 08 December 2018, http://dx.doi.org/10.1158/1538-7445.SABCS18-P6-20-04
    Conference Abstracts | 2018
    Hui MN; Cazet A; Elsworth B; Roden D; Cox T; Yang J; McFarland A; Deng N; Chan C-L; O'Toole S; Swarbrick A, 2018, 'Targeting the Hedgehog signalling pathway in triple negative breast cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, Vol. 36, http://dx.doi.org/10.1200/JCO.2018.36.15_suppl.e24216
    Preprints | 2018
    Roden DL; Baker LA; Elsworth B; Chan C-L; Harvey K; Deng N; Wu SZ; Cazet A; Nair R; Swarbrick A, 2018, Single cell transcriptomics reveals molecular subtype and functional heterogeneity in models of breast cancer, http://dx.doi.org/10.1101/282079
    Conference Abstracts | 2018
    Swarbrick A; Cazet A; Hui M; O'Toole S; Lim E; Martin M, 2018, 'Small molecule inhibition of smoothened in triple negative breast cancer-associated fibroblasts depletes cancer stem cells and sensitizes to cytotoxic chemotherapy in mice and humans', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, TX, San Antonio, Vol. 79, presented at San Antonio Breast Cancer Symposium, TX, San Antonio, 04 December 2018 - 08 December 2018, http://dx.doi.org/10.1158/1538-7445.SABCS18-P5-07-03
    Conference Abstracts | 2018
    Swarbrick A; Wu SZ; Roden D; Al-Eryani G; O'Toole S; Lim E, 2018, 'Landscape of the breast tumour microenvironment at single-cell resolution', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, TX, San Antonio, Vol. 79, presented at San Antonio Breast Cancer Symposium, TX, San Antonio, 04 December 2018 - 08 December 2018, http://dx.doi.org/10.1158/1538-7445.SABCS18-GS1-01
    Preprints | 2018
    Teo WS; Holliday H; Karthikeyan N; Cazet AS; Roden DL; Harvey K; Konrad CV; Murali R; Varghese BA; P. T. A; Chan C-L; McFarland A; Junankar S; Ye S; Yang J; Nikolic I; Shah JS; Baker LA; Millar EKA; Naylor MJ; Ormandy CJ; Lakhani SR; Kaplan W; Mellick AS; O’Toole SA; Swarbrick A; Nair R, 2018, Id proteins promote a cancer stem cell phenotype in triple negative breast cancer via negative regulation of Robo1, http://dx.doi.org/10.1101/497313
    Conference Abstracts | 2017
    Anderson RL; Swarbrick A; Johnstone R; Chua B; Gill A; Saunders C; Lakhani S; Lim E; Loi S; O'Toole SA; Khanna KK; Devereux L; Harvey K; Reed AM, 2017, 'Brocade: The National Breast Cancer Foundation Repository of Primary Tumours and Metastases from Breast Cancer Patients', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, Vol. 13, pp. 110 - 111, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000413954500136&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints | 2017
    Cazet A; Hui M; Elsworth B; Wu S; Roden D; Chan C-L; Skhinas J; Collot R; Yang J; Harvey K; Johan Z; Cooper C; Nair R; Herrmann D; McFarland A; Deng N-T; Ruiz-Borrego M; Rojo F; Trigo J; Bezares S; Caballero R; Lim E; Timpson P; O’Toole S; Watkins N; Cox T; Samuel M; Martín M; Swarbrick A, 2017, Targeting stromal remodeling and cancer stem cell plasticity to overcome chemoresistance in triple negative breast cancer, http://dx.doi.org/10.1101/215954
    Conference Abstracts | 2017
    Ho GY; Lieschke E; Kyran E; Shield-Artin K; Kondrashova O; Barker H; Hollian R; Cazet A; Thuan P; Swarbrick A; McNally O; Bowtell D; Wakefield M; Scott CL, 2017, 'Hedgehog inhibition impaired platinum response in high-grade serous ovarian cancer harboring high hedgehog ligand expression and mTOR pathway activation.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, Vol. 35, presented at 53rd Annual Clinical Science Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Symposium on Old Targets, New Drugs - Her2 and MET, IL, Chicago, 02 June 2017 - 07 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.5583
    Conference Abstracts | 2017
    Rojo F; Ruiz Borrego M; Hui M; Trigo Perez JM; Cazet A; Karsdal MA; Urruticoechea A; Antolin S; Garcia-Saenz JA; O'Toole S; Blach A; Perez-Ramos L; Bezares S; Sanchez-Arago M; Caballero R; Bager CL; Swarbrick A; Martin Jimenez M, 2017, 'Tumor microenvironment biomarkers as therapeutic strategies for TNBC', in ANNALS OF ONCOLOGY, OXFORD UNIV PRESS, SPAIN, Madrid, Vol. 28, presented at 42nd European-Society-for-Medical-Oncology Congress (ESMO), SPAIN, Madrid, 08 September 2017 - 12 September 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000411324004218&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Byrne NM; Khoo WH; Mourad N; Quinn JAPJ; Shah S; Mcdonald MM; Cazet A; Swarbrick A; Phan TG; Rogers MJ; Croucher PI, 2016, 'Identification of dormant prostate cancer cells in the skeleton in vivo and ex vivo', in BJU INTERNATIONAL, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 118, pp. 35 - 36, presented at 17th Asia-Pacific Prostate Cancer Conference, AUSTRALIA, Melbourne, 31 August 2016 - 03 September 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000381708200082&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Gallego-Ortega D; Ledger A; Roden D; Cho C; Allerdice SL; Lee HJ; Valdes-Mora F; Lee B; Kaplan W; Salomon R; Piggin C; Rabinovich B; Millar E; Chtanova T; Swarbrick A; Clark S; Ormandy C, 2015, 'The ETS transcription factor ELF5 drives metastasis via angiogenesis and recruitment of Gr-1+ CD11b+ myeloid derived suppressor cells in luminal breast cancer', in Clinical and Experimental Metastasis, Springer Verlag (Germany), Vol. 32, pp. 203 - 203, presented at MRS 15th International biennial congress of the metastasis research society, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351601900067&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Abstracts | 2015
    Nair R; Teo WS; Ye S; McFarland A; Harvey K; Roden D; Junankar S; Baker L; Yang J; Fluke N; Millar E; Mellick A; Naylor M; Ormandy C; Lakhani S; O'Toole S; Swarbrick A, 2015, 'The Inhibitor of Differentiation proteins mediate tumour-initiating properties and metastasis in breast cancer', in CLINICAL & EXPERIMENTAL METASTASIS, SPRINGER, Vol. 32, pp. 224 - 224, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351601900129&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Presentations | 2015
    Sax MJ; Plummer PN; Gasch C; Freeman R; Day CJ; Wei M; Swarbrick A; Mittal V; Mellick AS, 2015, 'Endothelial C-C chemokine receptor type 5 (CCR5) is required for tumor angiogenesis', Vol. 32, pp. 223 - 223, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351601900126&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2014
    Hui M; Yang J; Foreman N; McFarlane A; Cazet A; O'Toole S; Swarbrick A, 2014, 'TARGETING THE HEDGEHOG SIGNALLING PATHWAY IN TRIPLE NEGATIVE BREAST CANCER', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 128 - 128, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000345350900160&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Presentations | 2014
    Hui M; Yang J; McFarlane A; Cazet A; Swarbrick A, 2014, 'TARGETING THE HEDGEHOG SIGNALLING PATHWAY IN TRIPLE NEGATIVE BREAST CANCER', https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339716500008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Presentations | 2014
    Junankar S; Baker L; Yun K; Swarbrick A, 2014, 'Inhibitor of differentiation 4 (ID4) maintains mammary stem cell homeostasis and identifies a poor-prognosis subset of basal-like breast cancers with a putative stem cell of origin', presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-LB-62
    Conference Papers | 2014
    Mahon KL; Chiam K; Lee BY; Nguyen Q; Boyer MJ; Stockler M; Pavlakis N; Marx G; Mallesara G; Gurney H; Clark S; Swarbrick A; Daly R; Horvath L, 2014, 'CIRCULATING MICRORNAS ASSOCIATED WITH DOCETAXEL-RESISTANT CASTRATION-RESISTANT PROSTATE CANCER', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 26 - 27, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339716200012&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Plummer PN; Balsara S; Umer B; Taft R; Ferro V; Mattick JS; Swarbrick A; McMillan N; Mittal V; Mellick AS, 2013, 'MICRORNAS AS NOVEL ANTI-ANGIOGENESIS THERAPEUTIC TARGETS', in JOURNAL OF GENE MEDICINE, WILEY-BLACKWELL, AUSTRALIA, Univ Technol, Sydney, pp. 321 - 322, presented at 8th Meeting of the Australasian-Gene-Therapy-Society, AUSTRALIA, Univ Technol, Sydney, 08 May 2013 - 10 May 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000325102500023&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Warrier S; Sellinger C; Beith JM; Cazet A; Swarbrick A; Carmalt H; O'Toole S, 2013, 'Claudin-1 as a novel transcriptional target of hedgehog signaling and a predictor for outcome in breast cancer.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, presented at 49th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2013 - 04 June 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000335419600303&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2012
    Natividad KDT; Junankar S; Swarbrick A; Batten M, 2012, 'nterleukin-27 signaling promotes immunity against endogenously arising tumors', in CYTOKINE, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, SWITZERLAND, Geneva, pp. 538 - 538, presented at 10th Joint Meeting of the International-Cytokine-Society (ICS) / Meeting of the International-Society-for-Interferon-and-Cytokine-Research (ISICR), SWITZERLAND, Geneva, 11 September 2012 - 14 September 2012, http://dx.doi.org/10.1016/j.cyto.2012.06.148
    Conference Papers | 2012
    Teo W; Nair R; McFarland A; Ye S; Mellick A; Lakhani S; Swarbrick A, 2012, 'Dissecting the Role of the Inhibitor of Differentiation 1 in Breast Cancer Metastasis and Characterization of Pathways Controlling Breast Cancer Stem Cell Phenotype', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, Barcelona, SPAIN, pp. S37 - S37, presented at 22nd Biennial Congress of the European-Association-for-Cancer-Research, Barcelona, SPAIN, 07 July 2012 - 10 July 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000313036500138&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2011
    Plummer PN; Taft R; Mattick J; McMillan N; Swarbrick A; Brink R; Mittal V; Mellick AS, 2011, 'MICRORNAS AS TOOLS TO TARGET BONE MARROW MEDIATED TUMOUR ANGIOGENESIS', in JOURNAL OF GENE MEDICINE, WILEY, AUSTRALIA, Univ Melbourne, Bio21 Inst, Parkville, pp. 430 - 430, presented at 7th Biennial Meeting of the Australasian-Gene-Therapy-Society, AUSTRALIA, Univ Melbourne, Bio21 Inst, Parkville, 04 May 2011 - 06 May 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000297950900039&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2011
    Plummer PN; Taft R; Mattick J; McMillan N; Swarbrick A; Brink R; Mittal V; Mellick AS, 2011, 'MICRORNAS AS TOOLS TO TARGET BONE MARROW MEDIATED TUMOUR ANGIOGENESIS', in JOURNAL OF GENE MEDICINE, WILEY, AUSTRALIA, Univ Melbourne, Bio21 Inst, Parkville, pp. 443 - 443, presented at 7th Biennial Meeting of the Australasian-Gene-Therapy-Society, AUSTRALIA, Univ Melbourne, Bio21 Inst, Parkville, 04 May 2011 - 06 May 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000297950900061&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2010
    O'Toole SA; Machalek D; Shearer R; Millar EKA; Nair R; Martelotto L; McLeod D; Cooper C; Qiu MR; Sutherland RL; Watkins DN; Swarbrick A, 2010, 'Hedgehog Ligand Overexpression Predicts Poor Outcome in Breast Cancer and Is a Potential Therapeutic Target for Metastatic Disease', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 70, http://dx.doi.org/10.1158/0008-5472.SABCS10-S6-8
    Conference Papers | 2009
    O Toole SJ; Swarbrick A; Millar E; McLeod D; Mcneil CM; Qiu MR; Lopez-Knowles E; Caldon E; Oakes SR; Ormandy CJ; Morey AL; Musgrove EA; Henshall SM; Sutherland RL, 2009, 'Aberrent hedgehog signaling is an early event in breast cancer development', in Cancer research, American Association Cancer Research, Philadelphia, PA, pp. 70S - 70S
    Conference Papers | 2009
    O'Toole S; Swarbrick A; Millar E; McLeod D; McNeil C; Qiu M; Lopez-Knowles E; Caldon E; Oakes S; Ormandy C; Morey A; Musgrove E; Henshall S; Sutherland R, 2009, 'Aberrent hedgehog signaling is an early event in breast cancer development.', in Cancer Research, American Association for Cancer Research (AACR), pp. 24 - 24, http://dx.doi.org/10.1158/0008-5472.sabcs-24
    Conference Papers | 2002
    Swarbrick A; Hunter LJ; Lee CS; Sergio CM; Sutherland RL; Musgrove EA, 2002, 'Id1 is a critical target of c-Myc in breast cancer cells', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, CALIFORNIA, SAN FRANCISCO, pp. 433A - 433A, presented at 42nd Annual Meeting of the American-Society-for-Cell-Biology, CALIFORNIA, SAN FRANCISCO, 14 December 2002 - 18 December 2002, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000179569102437&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

https://www.swarbricklab.com/funding

 

NHMRC LEadership Fellowship (L2)

NHMRC Senior Research Fellowship

NSW Premier’s award for Outstanding Research Fellow, Cancer Institute NSW

NHMRC Career Development Fellowship II

CINSW Early Career Fellowship and NBCF Early Career Fellowship

Sydney University Medal for Excellence in Medical Research

NHMRC CJ Martin Fellowship

https://www.swarbricklab.com/

 

My Research Supervision

5 postdoctoral fellows

4 PhD students