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Associate Professor Angela Finch

Associate Professor Angela Finch

Associate Professor
Medicine & Health
School of Biomedical Sciences

Research Interests:
Research interests are molecular pharmacology and pedagogical research

Broad Research Areas:
Pharmacology

Society Memberships & Professional Activities:
ASCEPT

Specific Research Keywords:
Education Research, Pharmacology
Phone
+61 2 9065 1017
E-mail
a.finch@unsw.edu.au
  • Books | 2012
    2012, School of Medical Sciences Honours Course Manual, Polly P; Hardman CD; Finch AM, (eds.), School of Medical Sciences, Faculty of Medicine, UNSW, Sydney, Australia
    Books | 2011
    2011, School of Medical Sciences Honours Course Manual, Polly P; Hardman CD; Finch AM, (eds.), School of Medical Sciences, Faculty of Medicine, UNSW, Sydney, Australia
  • Book Chapters | 2005
    Finch A; Sarramegna V; Graham RM, 2005, 'Ligand binding, activation and agonist trafficking', in Perez DM (ed.), The Adrenergic Receptors in the 21st Century, Humana Press, New Jersey, NJ, pp. 25 - 86
  • Journal articles | 2023
    Stavrou MR; So SS; Finch AM; Ballouz S; Smith NJ, 2023, 'Gene expression analyses of TAS1R taste receptors relevant to the treatment of cardiometabolic disease', Chemical Senses, 48, http://dx.doi.org/10.1093/chemse/bjad027
    Journal articles | 2022
    Chen J; Campbell AP; Wakelin LPG; Finch AM, 2022, 'Characterisation of bis(4-aminoquinoline)s as α1A adrenoceptor allosteric modulators', European Journal of Pharmacology, 916, http://dx.doi.org/10.1016/j.ejphar.2021.174659
    Journal articles | 2022
    Wilkins BP; Finch AM; Wang Y; Smith NJ, 2022, 'Orphan GPR146: an alternative therapeutic pathway to achieve cholesterol homeostasis?', Trends in Endocrinology and Metabolism, 33, pp. 481 - 492, http://dx.doi.org/10.1016/j.tem.2022.04.008
    Journal articles | 2021
    Ngo T; Wilkins BP; So SS; Keov P; Chahal KK; Finch AM; Coleman JLJ; Kufareva I; Smith NJ, 2021, 'Orphan receptor GPR37L1 remains unliganded', Nature Chemical Biology, 17, pp. 383 - 386, http://dx.doi.org/10.1038/s41589-021-00748-z
    Journal articles | 2021
    Smith NJ; Grant JN; Moon JI; So SS; Finch AM, 2021, 'Critically evaluating sweet taste receptor expression and signaling through a molecular pharmacology lens', FEBS Journal, 288, pp. 2660 - 2672, http://dx.doi.org/10.1111/febs.15768
    Journal articles | 2020
    Lizarme-Salas Y; Ariawan AD; Ratnayake R; Luesch H; Finch A; Hunter L, 2020, 'Vicinal difluorination as a C=C surrogate: An analog of piperine with enhanced solubility, photostability, and acetylcholinesterase inhibitory activity', Beilstein Journal of Organic Chemistry, 16, pp. 2663 - 2670, http://dx.doi.org/10.3762/BJOC.16.216
    Journal articles | 2020
    Lizarme-Salas Y; Ariawan AD; Ratnayake R; Luesch H; Finch A; Hunter L, 2020, 'Vicinal difluorination as a C=C surrogate: an analog of piperine with enhanced solubility, photostability, and acetylcholinesterase inhibitory activity', , http://dx.doi.org/10.3762/bxiv.2020.93.v1
    Journal articles | 2020
    Ngo T; Wilkins B; So S; Keov P; Chahal K; Finch A; Coleman JLJ; Kufareva I; Smith N, 2020, 'Orphan G protein-coupled receptor, GPR37L1: pharmacological toolbox empty once again', , http://dx.doi.org/10.1101/2020.09.11.290486
    Journal articles | 2018
    Healey RD; Wojciechowski JP; Monserrat-Martinez A; Tan SL; Marquis CP; Sierecki E; Gambin Y; Finch AM; Thordarson P, 2018, 'Design, Synthesis, and Evaluation of N- and C-Terminal Protein Bioconjugates as G Protein-Coupled Receptor Agonists', Bioconjugate Chemistry, 29, pp. 403 - 409, http://dx.doi.org/10.1021/acs.bioconjchem.7b00716
    Journal articles | 2017
    Campbell AP; Wakelin LPG; Denny WA; Finch AM, 2017, 'Homobivalent conjugation increases the allosteric effect of 9-aminoacridine at the α1-adrenergic receptors', Molecular Pharmacology, 91, pp. 135 - 144, http://dx.doi.org/10.1124/mol.116.105874
    Journal articles | 2017
    Urmi KF; Finch AM; Griffith R, 2017, 'Template selection and refinement considerations for modelling aminergic GPCR-ligand complexes', Journal of Molecular Graphics and Modelling, 76, pp. 488 - 503, http://dx.doi.org/10.1016/j.jmgm.2017.07.030
    Journal articles | 2014
    Campbell AP; MacDougall IJA; Griffith R; Finch AM, 2014, 'An aspartate in the second extracellular loop of the α1B adrenoceptor regulates agonist binding', European Journal of Pharmacology, 733, pp. 90 - 96, http://dx.doi.org/10.1016/j.ejphar.2014.03.034
    Journal articles | 2014
    Chen J; Campbell AP; Urmi KF; Wakelin LPG; Denny WA; Griffith R; Finch AM, 2014, 'Human α1-adrenoceptor subtype selectivity of substituted homobivalent 4-aminoquinolines', Bioorganic and Medicinal Chemistry, 22, pp. 5910 - 5916, http://dx.doi.org/10.1016/j.bmc.2014.09.017
    Journal articles | 2014
    Kim MY; Finch AM; Lumbers ER; Boyce AC; Gibson KJ; Eiby YA; Lingwood BE, 2014, 'Expression of adrenoceptor subtypes in preterm piglet heart is different to term heart', PLoS ONE, 9, http://dx.doi.org/10.1371/journal.pone.0092167
    Journal articles | 2013
    Chen J; Murad AK; Wakelin L; Denny WA; Griffith R; Finch AM, 2013, 'a1-Adrenoceptor and serotonin 5-HT1A receptor affinity of homobivalent 4-aminoquinoline compounds: An investigation of the effect of linker length', Biochemical Pharmacology, 85, pp. 1534 - 1541, http://dx.doi.org/10.1016/j.bcp.2013.03.010
    Journal articles | 2013
    Ngo T; Nicholas TJ; Chen J; Finch AM; Griffith R, 2013, '5-HT1A receptor pharmacophores to screen for off-target activity of á1-adrenoceptor antagonists', Journal of Computer - Aided Molecular Design, 27, pp. 305 - 319, http://dx.doi.org/10.1007/s10822-013-9647-5
    Journal articles | 2011
    Stoddart ES; Senadheera SN; MacDougall I; Griffith R; Finch AM, 2011, 'A novel structural framework for á1a/d-adrenoceptor selective antagonists identified using subtype selective pharmacophores', PLoS One, 6, pp. e19695, http://dx.doi.org/10.1371/journal.pone.0019695
    Journal articles | 2008
    Antipatis C; Finch A; Ashworth C, 2008, 'Effect of controlled alterations in maternal dietary retinol on foetal and neonatal retinol status and pregnancy outcome in pigs', Livestock Science, 118, pp. 247 - 254
    Journal articles | 2008
    Laird AS; Finch A; Waite PM; Carrive P, 2008, 'Peripheral changes above and below injury level lead to prolonged vascular responses following high spinal cord injury', American Journal of Physiology - Heart and Circulatory Physiology, 294, pp. H785 - H792, http://dx.doi.org/10.1152/ajpheart.01002.2007
    Journal articles | 2008
    Riek RP; Finch A; Begg G; Graham RM, 2008, 'Wide turn diversity in protein transmembrane helices implications for G-protein-coupled receptor and other polytopic membrane protein structure and function', Molecular Pharmacology, 73, pp. 1092 - 1104, http://dx.doi.org/10.1124/mol.107.043042
    Journal articles | 2007
    Mcneil CJ; Nwagwu MO; Finch A; Page KP; Thain A; Mcardle HJ; Ashworth C, 2007, 'Glucocorticoid exposure and tissue gene expression of 11â HSD-1, 11 â HSD-2, and glucocorticoid receptor in a porcine model of differential fetal growth', Reproduction, 133, pp. 653 - 661
    Journal articles | 2006
    Du X; Gao X; Kiriazis H; Moore X; Ming Z; Su Y; Finch A; Hannan R; Dart A; Graham RM, 2006, 'Transgenic alpha(1A)-adrenergic activation limits post-infarct ventricular remodeling and dysfunction and improves survival', Cardiovascular Research, 71, pp. 735 - 743
    Journal articles | 2006
    Du XR; Gao X; Kiriazis H; Moore X; Ming Z; Su Y; Wang K; Finch A; Dart A; Graham RM, 2006, 'Cardiac overexpression of the alpha(1A)-adrenergic receptor limits post-infarct ventricular remodeling and dysfunction, and improves survival', Journal of Molecular and Cellular Cardiology, 41, pp. 735 - 735
    Journal articles | 2006
    Finch A; Graham RM, 2006, 'The alpha(1D)-adrenergic receptor: Cinderella or ugly stepsister', Molecular Pharmacology, 69, pp. 1 - 4
    Journal articles | 2006
    Finch AM; Graham RM, 2006, 'The α1D-adrenergic receptor: Cinderella or ugly stepsister', Molecular Pharmacology, 69, pp. 1 - 4, http://dx.doi.org/10.1124/mol.105.020230
    Journal articles | 2005
    Mcneil CJ; Finch A; Page KP; Clarke SD; Ashworth C; Mcardle HJ, 2005, 'The effect of fetal pig size and stage of gestation on tissue fatty acid metabolism and profile', Reproduction, 129, pp. 757 - 763
    Journal articles | 2004
    Du X; Fang L; Gao X; Kiriazis H; Feng X; Hotchkin E; Finch AM; Chaulet H; Graham RM, 2004, 'Genetic enhancement of ventricular contractility protects against pressure-overload-induced cardiac dysfunction', Journal of Molecular and Cellular Cardiology, 37, pp. 979 - 987
    Journal articles | 2004
    Finch A; Yang LG; Nwagwu MO; Page KP; Mcardle HJ; Ashworth C, 2004, 'Placental transport of leucine in a porcine model of low birth weight', Reproduction, 128, pp. 229 - 235
    Journal articles | 2004
    McGinty SJ; Finch AM; Griffith R; Graham RM; Bremner JB, 2004, 'Synthesis and biological evaluation of bicyclic and tricyclic substituted nortropan derivatives: discovery of a novel selective Ą1D-adrenergic receptor ligand', Bioorganic and Medicinal Chemistry, 12, pp. 5639 - 5650
    Journal articles | 2003
    Page KP; Ashworth C; Mcardle HJ; Finch A; Nwagwu MO, 2003, 'Sodium transport across the chorioallantoic membrane of porcine placenta involves the epithelial sodium channel (ENaC)', The Journal of Physiology, 547, pp. 849 - 857, http://dx.doi.org/10.1113/jphysiol.2002.031153
    Journal articles | 2002
    Finch AM; Antipatis C; Pickard AR; Ashworth CJ, 2002, 'Patterns of fetal growth within Large White x Landrace and Chinese Meishan gilt litters at three stages of gestation', Reproduction, Fertility and Development, 14, pp. 419 - 425, http://dx.doi.org/10.1071/RD01131
    Journal articles | 2001
    Ashworth CJ; Finch AM; Page KR; Nwagwu MO; McArdle HJ, 2001, 'Causes and consequences of fetal growth retardation in pigs.', Reproduction (Cambridge, England) Supplement, 58, pp. 233 - 246
    Journal articles | 2001
    Rocke JA; Sinclair AG; Edwards SA; Cordoba R; Pkiyach S; Penny PC; Penny P; Finch AM; Horgan GW, 2001, 'The effect of feeding salmon oil to sows throughout pregnancy on pre-weaning mortality of piglets', Animal Science, 73, pp. 489 - 500, http://dx.doi.org/10.1017/s135772980005846x
    Journal articles | 1999
    Finch AM; Wong AK; Paczkowski NJ; Wadi SK; Craik DJ; Fairlie DP; Taylor SM, 1999, 'Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a', Journal of Medicinal Chemistry, 42, pp. 1965 - 1974, http://dx.doi.org/10.1021/jm9806594
    Journal articles | 1999
    Paczkowski NJ; Finch AM; Whitmore JB; Short AJ; Wong AK; Monk PN; Cain SA; Fairlie DP; Taylor SM, 1999, 'Pharmacological characterization of antagonists of the C5a receptor', British Journal of Pharmacology, 128, pp. 1461 - 1466, http://dx.doi.org/10.1038/sj.bjp.0702938
    Journal articles | 1999
    Short A; Wong AK; Finch AM; Haaima G; Shiels IA; Fairlie DP; Taylor SM, 1999, 'Effects of a new C5a receptor antagonist on C5a- and endotoxin-induced neutropenia in the rat', British Journal of Pharmacology, 126, pp. 551 - 554, http://dx.doi.org/10.1038/sj.bjp.0702338
    Journal articles | 1999
    Vogen SM; Finch AM; Wadi SK; Thatcher J; Monk PN; Taylor SM; Sanderson SD, 1999, 'The influence of Lys68 in decapeptide agonists of C5a on C5a receptor binding, activation and selectivity', Journal of Peptide Research, 53, pp. 8 - 17, http://dx.doi.org/10.1111/j.1399-3011.1999.tb01612.x
    Journal articles | 1998
    Wong AK; Finch AM; Pierens GK; Craik DJ; Taylor SM; Fairlie DP, 1998, 'Small molecular probes for G-protein-coupled C5a receptors: Conformationally constrained antagonists derived from the C terminus of the human plasma protein C5a', Journal of Medicinal Chemistry, 41, pp. 3417 - 3425, http://dx.doi.org/10.1021/jm9800651
    Journal articles | 1997
    Finch AM; Vogen SM; Sherman SA; Kirnarsky L; Taylor SM; Sanderson SD, 1997, 'Biologically active conformer of the effector region of human C5a and modulatory effects of N-terminal receptor binding determinants on activity', Journal of Medicinal Chemistry, 40, pp. 877 - 884, http://dx.doi.org/10.1021/jm960727r
    Journal articles | 1997
    Tempero RM; Hollingsworth MA; Burdick MD; Finch AM; Taylor SM; Vogen SM; Morgan EL; Sanderson SD, 1997, 'Molecular Adjuvant Effects of a Conformationally Biased Agonist of Human C5a Anaphylatoxin', Journal of Immunology, 158, pp. 1377 - 1382
    Journal articles | 1996
    Kawatsu R; Sanderson SD; Blanco I; Kendall N; Finch AM; Taylor SM; Colcher D, 1996, 'Conformationally biased analogs of human C5a mediate changes in vascular permeability', Journal of Pharmacology and Experimental Therapeutics, 278, pp. 432 - 440
    Journal articles | 1995
    Finch AM; Heron AE; Tolhurst SL; Florin TH; Sanderson SD; Taylor SM, 1995, 'The effect of C5a and U46619 on the isolated, perfused human placental lobule: Development of a method for the online estimation of tissue fluid accumulation', Journal of Pharmacological and Toxicological Methods, 34, pp. 133 - 141, http://dx.doi.org/10.1016/1056-8719(95)00046-3
    Journal articles | 1995
    Sanderson SD; Kimarsky L; Sherman SA; Vogen SM; Prakash O; Finch AM; Taylor SM; Ember JA, 1995, 'Decapeptide Agonists of Human C5a: The Relationship between Conformation and Neutrophil Response', Journal of Medicinal Chemistry, 38, pp. 3669 - 3675, http://dx.doi.org/10.1021/jm00018a028
    Journal articles | 1994
    Sanderson SD; Kimarsky L; Sherman SA; Ember JA; Finch AM; Taylor SM, 1994, 'Decapeptide Agonists of Human C5a: The Relationship between Conformation and Spasmogenic and Platelet Aggregatory Activities', Journal of Medicinal Chemistry, 37, pp. 3171 - 3180, http://dx.doi.org/10.1021/jm00045a023
    Journal articles | 1994
    Taylor SM; Finch AM; Heron AE; Brown LC; Florin THJ, 1994, 'Reversibility of tachyphylaxis to C5a in guinea pig tissues, perfused human placental lobule, and umbilical artery', Inflammation, 18, pp. 645 - 657, http://dx.doi.org/10.1007/BF01535262
  • Conference Abstracts | 2018
    Tan S; Healey R; Thordarson P; Finch A, 2018, 'Investigating the Impact of Altered Subunit Expression on Sweet Taste Receptor Surface Trafficking and Signaling', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, CA, Amer Assoc Anatomists, San Diego, Vol. 32, presented at Experimental Biology Meeting, CA, Amer Assoc Anatomists, San Diego, 21 April 2018 - 25 April 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000436986700214&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2004
    Du X; Fang L; Gao X; Kiriazis H; Feng H; Hotchkins E; Mearns BM; Finch AM; Graham RM, 2004, 'Genetic enhancenment of ventricular contractility protects against pressure - overload-induced cardiac dysfunction', in Journal of Molecular and Cellular Cardiology, Academic Press Ltd Elsevier Science Ltd, London, England, pp. 363 - 364, presented at Journal of Molecular and Cellular Cardiology
    Conference Papers | 2003
    McNeil C; Finch AM; Page KR; Clarke SD; Ashworth CJ; McArdle HJ, 2003, 'Relationship between hepatic fatty acid profile and delta-6-desaturase gene expression in different sized pig fetuses at three stages of gestation.', in PEDIATRIC RESEARCH, INT PEDIATRIC RESEARCH FOUNDATION, INC, ENGLAND, BRIGHTON, pp. 16A - 16A, presented at 2nd World Congress on Dietal Origins of Adult Disease, ENGLAND, BRIGHTON, 07 June 2003 - 10 June 2003, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000183333800113&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2002
    Nwagwu M; Page KR; Thain A; Finch AM; McArdle HJ; Ashworth CJ, 2002, 'Differences in fetal pig plasma cortisol between inadequately grown and normal-sized fetuses are not related to changes in fetal plasma ACTH', in JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, pp. 116P - 117P, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000174618200157&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2002
    Page KR; Ashworth CJ; McArdle HJ; Finch AM; Nwagwu MO, 2002, 'Sodium transport across chorioallantoic membrane of porcine placenta at days 45 and 100 of gestation', in JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, pp. 127P - 128P, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000174618200173&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2000
    F'inch AM; Ashworth CJ; McArdle HJ, 2000, 'Is nutrient delivery altered in the placenta supplying the runt piglet?', in JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, pp. 177P - 177P, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000085937100254&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2000
    Finch AM; Ashworth CJ; Page KR; McArdle HJ, 2000, 'Gestational changes in leucine transport across porcine placentas supplying littermates of different sizes', in JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, pp. 26P - 27P, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000165837800034&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2000
    Page KR; Ashworth CJ; McArdle HJ; Finch AM; Nwagwu MO, 2000, 'Effect of amiloride on short-circuit currents across the chorioallantoic membrane of the porcine placenta', in JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, pp. 20P - 21P, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000165837800025&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1997
    Wong AK; Finch AM; Pierens GK; Taylor SM; Fairlie DP, 1997, 'Conformationally constrained small molecule antagonists of C5a.', in ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, pp. 9 - MEDI, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997XQ85702469&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1