Dr Anthony Byrne

Dr Anthony Byrne

Conjoint Associate Professor

PhD MBBS MIPH BAppSc FRACP

Medicine & Health
School of Clinical Medicine

Dr Anthony Byrne is a thoracic physician and researcher with a strong interest in respiratory infections, asthma and structural lung disease. His doctoral studies focused on the link between tuberculosis and chronic respiratory disease including asthma and chronic obstructive pulmonary disease among patients in Lima, Peru.

Dr Byrne is a staff specialist respiratory physician at St Vincent’s public and private hospitals and has consulting rooms at St Vincent’s Clinic, Darlinghurst. He is a Cochrane author and associate editor with the “Cochrane Clinical Answers” initiative, dedicated to providing bite-size, clinician-focused summaries of high-quality systematic reviews. 

 

Current Positions 
    

Staff Specialist in Respiratory Medicine, St Vincent’s Public and Private Hospitals, Sydney. 

Staff Specialist in Respiratory Medicine, Blacktown Public Hospital, Sydney.


Conjoint Associate Lecturer of Medicine: St Vincent’s Clinical School, UNSW.


Author, Cochrane Clinical Answers, Cochrane Review Group 

Respiratory Physician: St Vincent’s Clinic suite 806, Victoria St, Sydney (Private Practice) 
 

Phone
+612 83826822
Location
Dr Anthony Byrne PhD MBBS MIPH BAppSc FRACP Staff Specialist Thoracic Physician Staff specialist St Vincent's and Blacktown Hospitals, Sydney Australia. Respiratory Physician St Vincent's Clinic, Suite 806 Level 8, Darlinghurst. Principal Investigator Socios En Salud, Partners In Health Peru.
  • Book Chapters | 2023
    Rachow A; Walker NF; Allwood B; van der Zalm MM; Byrne A; Meghji J, 2023, 'The challenge of post-tuberculosis lung disease', in The Challenge of Tuberculosis in the 21st Century, European Respiratory Society, pp. 191 - 209, http://dx.doi.org/10.1183/2312508x.10025122
    Book Chapters | 2021
    Alffenaar JWC; Kim HY; Byrne A; Piubello A; Migliori GB, 2021, 'Monitoring Treatment: Clinical and Programmatic Approach for Drug-Susceptible and Drug-Resistant Tuberculosis', in Essential Tuberculosis, Springer International Publishing, pp. 163 - 170, http://dx.doi.org/10.1007/978-3-030-66703-0_18
  • Journal articles | 2023
    Cysique LA; Jakabek D; Bracken SG; Allen-Davidian Y; Heng B; Chow S; Dehhaghi M; Staats Pires A; Darley DR; Byrne A; Phetsouphanh C; Kelleher A; Dore GJ; Matthews GV; Guillemin GJ; Brew BJ, 2023, 'The kynurenine pathway relates to post-acute COVID-19 objective cognitive impairment and PASC', Annals of Clinical and Translational Neurology, 10, pp. 1338 - 1352, http://dx.doi.org/10.1002/acn3.51825
    Journal articles | 2023
    Dorvil N; Rivera VR; Riviere C; Berman R; Severe P; Bang H; Lavoile K; Devieux JG; Faustin M; Saintyl G; Mendicuti MD; Pierre S; Apollon A; Dumond E; Forestal GPL; Rouzier V; Marcelin A; McNairy ML; Walsh KF; Dupnik K; Reif LK; Byrne AL; Bousleiman S; Orvis E; Joseph P; Cremieux PY; Pape JW; Koenig SP, 2023, 'Same-day testing with initiation of antiretroviral therapy or tuberculosis treatment versus standard care for persons presenting with tuberculosis symptoms at HIV diagnosis: A randomized open-label trial from Haiti', PLoS Medicine, 20, pp. e1004246, http://dx.doi.org/10.1371/journal.pmed.1004246
    Journal articles | 2023
    Nightingale R; Carlin F; Meghji J; McMullen K; Evans D; van der Zalm MM; Anthony MG; Bittencourt M; Byrne A; du Preez K; Coetzee M; Feris C; Goussard P; Hirasen K; Bouwer J; Hoddinott G; Huaman MA; Inglis-Jassiem G; Ivanova O; Karmadwala F; Schaaf HS; Schoeman I; Seddon JA; Sineke T; Solomons R; Thiart M; van Toorn R; Fujiwara PI; Romanowski K; Marais S; Hesseling AC; Johnston J; Allwood B; Muhwa JC; Mortimer K, 2023, 'Post-TB health and wellbeing', International Journal of Tuberculosis and Lung Disease, 27, pp. 248 - 283, http://dx.doi.org/10.5588/ijtld.22.0514
    Journal articles | 2023
    Pham JP; Boot M; Stefani M; Chapman S; Byrne A; Abdel-Shaheed C; Girgis L, 2023, 'Disseminated Mycobacterium chelonae infection complicating rheumatoid arthritis: A case report and review of the literature', International Journal of Rheumatic Diseases, 26, pp. 1167 - 1171, http://dx.doi.org/10.1111/1756-185X.14605
    Journal articles | 2021
    Alene KA; Wangdi K; Colquhoun S; Chani K; Islam T; Rahevar K; Morishita F; Byrne A; Clark J; Viney K, 2021, 'Tuberculosis related disability: a systematic review and meta-analysis', BMC Medicine, 19, http://dx.doi.org/10.1186/s12916-021-02063-9
    Journal articles | 2021
    Alffenaar JW; Märtson AG; Heysell SK; Cho JG; Patanwala A; Burch G; Kim HY; Sturkenboom MGG; Byrne A; Marriott D; Sandaradura I; Tiberi S; Sintchencko V; Srivastava S; Peloquin CA, 2021, 'Therapeutic Drug Monitoring in Non-Tuberculosis Mycobacteria Infections', Clinical Pharmacokinetics, 60, pp. 711 - 725, http://dx.doi.org/10.1007/s40262-021-01000-6
    Journal articles | 2021
    Allwood BW; Byrne A; Meghji J; Rachow A; Van Der Zalm MM; Schoch OD, 2021, 'Post-Tuberculosis Lung Disease: Clinical Review of an Under-Recognised Global Challenge', Respiration, 100, pp. 751 - 763, http://dx.doi.org/10.1159/000512531
    Journal articles | 2021
    Darley D; Matthews G; Dore G; Wilhelm K; Plit M; Stone E; Byrne A; Tonga K; Andresen D; Kelleher A; Cysique L; Cunningham P; Brew B, 2021, 'Persistent symptoms up to four months after community and hospital- managed SARS- CoV- 2 infection', Medical Journal of Australia, http://dx.doi.org/10.5694/mja2.50963
    Journal articles | 2021
    Darley DR; Dore GJ; Byrne A; Plit M; Brew BJ; Kelleher A; Matthews GV, 2021, 'Limited recovery from post-acute sequelae of SARS-CoV-2 (PASC) at eight months in a prospective cohort', , http://dx.doi.org/10.1101/2021.03.29.21254211
    Journal articles | 2021
    Darley DR; Dore GJ; Byrne AL; Plit ML; Brew BJ; Kelleher A; Matthews GV, 2021, 'Limited recovery from post-acute sequelae of sars-cov-2 at 8 months in a prospective cohort', ERJ Open Research, 7, pp. 00384 - 2021, http://dx.doi.org/10.1183/23120541.00384-2021
    Journal articles | 2021
    Di Michiel J; Gawthorne J; Shivam A; Maruno K; Cohn S; Lemon C; Liu Z; Byrne A, 2021, 'Lung health in the solomon islands: A mixed methods study', International Journal of COPD, 16, pp. 3093 - 3103, http://dx.doi.org/10.2147/COPD.S331734
    Journal articles | 2021
    Joseph Y; Yao Z; Dua A; Severe P; Collins SE; Bang H; Antoine Jean-Juste M; Ocheretina O; Apollon A; McNairy ML; Dupnik K; Cremieux E; Byrne A; Pape JW; Koenig SP, 2021, 'Long-term mortality after tuberculosis treatment among persons living with HIV in Haiti', Journal of the International AIDS Society, 24, pp. e25721, http://dx.doi.org/10.1002/jia2.25721
    Journal articles | 2021
    Menzies NA; Quaife M; Allwood BW; Byrne AL; Coussens AK; Harries AD; Marx FM; Meghji J; Pedrazzoli D; Salomon JA; Sweeney S; van Kampen SC; Wallis RS; Houben RMGJ; Cohen T, 2021, 'Lifetime burden of disease due to incident tuberculosis: a global reappraisal including post-tuberculosis sequelae', The Lancet Global Health, 9, pp. e1679 - e1687, http://dx.doi.org/10.1016/S2214-109X(21)00367-3
    Journal articles | 2021
    Migliori GB; Marx FM; Ambrosino N; Zampogna E; Schaaf HS; van der Zalm MM; Allwood B; Byrne AL; Mortimer K; Wallis RS; Fox GJ; Leung CC; Chakaya JM; Seaworth B; Rachow A; Marais BJ; Furin J; Akkerman OW; Al Yaquobi F; Amaral AFS; Borisov S; Caminero JA; Carvalho ACC; Chesov D; Codecasa LR; Teixeira RC; Dalcolmo MP; Datta S; Dinh-Xuan AT; Duarte R; Evans CA; García-García JM; Günther G; Hoddinott G; Huddart S; Ivanova O; Laniado-Laborín R; Manga S; Manika K; Mariandyshev A; Mello FCQ; Mpagama SG; Muñoz-Torrico M; Nahid P; Ong CWM; Palmero DJ; Piubello A; Pontali E; Silva DR; Singla R; Spanevello A; Tiberi S; Udwadia ZF; Vitacca M; Centis R; D'Ambrosio L; Sotgiu G; Lange C; Visca D, 2021, 'Clinical standards for the assessment, management and rehabilitation of post-TB lung disease', International Journal of Tuberculosis and Lung Disease, 25, pp. 797 - 813, http://dx.doi.org/10.5588/ijtld.21.0425
    Journal articles | 2020
    Allwood BW; Van Der Zalm MM; Amaral AFS; Byrne A; Datta S; Egere U; Evans CA; Evans D; Gray DM; Hoddinott G; Ivanova O; Jones R; Makanda G; Marx FM; Meghji J; Mpagama S; Pasipanodya JG; Rachow A; Schoeman I; Shaw J; Stek C; Van Kampen S; Von Delft D; Walker NF; Wallis RS; Mortimer K, 2020, 'Post-tuberculosis lung health: Perspectives from the First International Symposium', International Journal of Tuberculosis and Lung Disease, 24, pp. 820 - 828, http://dx.doi.org/10.5588/ijtld.20.0067
    Journal articles | 2020
    Byrne AL; Bennett MH; Chatterji R; Symons R; Thomas PS, 2020, 'Arterial and venous blood gases in exacerbations of chronic obstructive pulmonary disease', Internal Medicine Journal, 50, pp. 133 - 134, http://dx.doi.org/10.1111/imj.14692
    Journal articles | 2020
    Coates MM; Kintu A; Gupta N; Wroe EB; Adler AJ; Kwan GF; Park PH; Rajbhandari R; Byrne AL; Casey DC; Bukhman G, 2020, 'Burden of non-communicable diseases from infectious causes in 2017: a modelling study', The Lancet Global Health, 8, pp. e1489 - e1498, http://dx.doi.org/10.1016/S2214-109X(20)30358-2
    Journal articles | 2020
    Robertson DJ; Sanders JG; Towler A; Kramer RSS; Spowage J; Byrne A; Burton AM; Jenkins R, 2020, 'Hyper-realistic Face Masks in a Live Passport-Checking Task', Perception, 49, pp. 298 - 309, http://dx.doi.org/10.1177/0301006620904614
    Journal articles | 2020
    Yeong C; Byrne AL; Cho JG; Sintchenko V; Crighton T; Marais BJ, 2020, 'Use of GeneXpert MTB/RIF on a single pooled sputum specimen to exclude pulmonary tuberculosis among hospital inpatients placed in respiratory isolation', International Journal of Infectious Diseases, 92, pp. 175 - 180, http://dx.doi.org/10.1016/j.ijid.2019.12.024
    Journal articles | 2019
    Byrne AL; Marais BJ; Mitnick CD; Garden FL; Lecca L; Contreras C; Yauri Y; Garcia F; Marks GB, 2019, 'Asthma and atopy prevalence are not reduced among former tuberculosis patients compared with controls in Lima, Peru', BMC Pulmonary Medicine, 19, pp. 40, http://dx.doi.org/10.1186/s12890-019-0804-z
    Journal articles | 2018
    Byrne AL; Fox GJ; Marais BJ, 2018, 'Better than a pound of cure: Preventing the development of multidrug-resistant tuberculosis', Future Microbiology, 13, pp. 577 - 588, http://dx.doi.org/10.2217/fmb-2017-0236
    Journal articles | 2018
    Byrne AL; Marais BJ; Mitnick CD; Garden FL; Lecca L; Contreras C; Yauri Y; Garcia F; Marks GB, 2018, 'Feasibility and yield of screening for non-communicable diseases among treated tuberculosis patients in Peru', International Journal of Tuberculosis and Lung Disease, 22, pp. 86 - 92, http://dx.doi.org/10.5588/ijtld.17.0381
    Journal articles | 2017
    Byrne AL; Marais BJ; Mitnick CD; Garden FL; Lecca L; Contreras C; Yauri Y; Garcia F; Marks GB, 2017, 'Chronic airflow obstruction after successful treatment of multidrug-resistant tuberculosis', ERJ Open Research, 3, http://dx.doi.org/10.1183/23120541.00026-2017
    Journal articles | 2017
    Hayman YA; Sadofsky LR; Williamson JD; Hart SP; Morice AH, 2017, 'The effects of exogenous lipid on THP-1 cells: an in vitro model of airway aspiration?', ERJ Open Res, 3, http://dx.doi.org/10.1183/23120541.00026-2016
    Journal articles | 2017
    Ho J; Byrne AL; Linh NN; Jaramillo E; Fox GJ, 2017, 'Decentralized care for multidrug-resistant tuberculosis: A systematic review and meta-analysis', Bulletin of the World Health Organization, 95, pp. 584 - 593, http://dx.doi.org/10.2471/BLT.17.193375
    Journal articles | 2017
    Hovey EJ; Field KM; Rosenthal MA; Barnes EH; Cher L; Nowak AK; Wheeler H; Sawkins K; Livingstone A; Phal P; Goh C; Simes J; Kelly P; Hayden A; Barnes E; Espinoza D; Brown C; Winter D; Tomes B; Pike R; Simes J; Garrett L; Kilsby H; Freilich R; Arzhintar I; Dowling A; Ranieri N; Jennens R; Osmond F; Patterson KW; Phay A; Byrne A; Begbie S; Williams P; Kirby-Lewis S; Abell F; Plowman L; Flynn J; Inglis P; Ives A; Lobb S; Lwin Z; Woodward N; Crosbie G; Singhal N; Smith S; Whelan M, 2017, 'Continuing or ceasing bevacizumab beyond progression in recurrent glioblastoma: An exploratory randomized phase II trial', Neuro-Oncology Practice, 4, pp. 171 - 181, http://dx.doi.org/10.1093/nop/npw025
    Journal articles | 2015
    Byrne AL; Marais BJ; Mitnick CD; Lecca L; Marks GB, 2015, 'Risk factors for and origins of COPD', The Lancet, 385, pp. 1723 - 1724, http://dx.doi.org/10.1016/S0140-6736(15)60884-4
    Journal articles | 2015
    Byrne AL; Marais BJ; Mitnick CD; Lecca L; Marks GB, 2015, 'Tuberculosis and chronic respiratory disease: A systematic review', International Journal of Infectious Diseases, 32, pp. 138 - 146, http://dx.doi.org/10.1016/j.ijid.2014.12.016
    Journal articles | 2015
    Field KM; Simes J; Nowak AK; Cher L; Wheeler H; Hovey EJ; Brown CSB; Barnes EH; Sawkins K; Livingstone A; Freilich R; Phal PM; Fitt G; Rosenthal MA; Arzhintar I; Garrett L; Byrne A; Dowling A; Ranieri N; Jennens R; Osmond F; Patterson WK; Phay A; Abell F; Plowman L; Flynn J; Hovey E; Kilsby H; Kirby-Lewis S; Singhal N; Smith S; Whelan M; Inglis P; Ives A; Nowak A; Lobb S; Begbie S; Williams P; Lwin Z; Woodward N; Crosbie G; Harrup R; Pyszkowski L; Gauden S; Neville A, 2015, 'Randomized phase 2 study of carboplatin and bevacizumab in recurrent glioblastoma', Neuro-Oncology, 17, pp. 1504 - 1513, http://dx.doi.org/10.1093/neuonc/nov104
    Journal articles | 2014
    Byrne A; Bennett M; Chatterji R; Symons R; Pace N; Thomas P, 2014, 'Comparison of peripheral venous and arterial blood gas analyses Reply', RESPIROLOGY, 19, pp. 769 - 770, http://dx.doi.org/10.1111/resp.12300
    Journal articles | 2014
    Byrne A; Bennett M; Chatterji R; Symons R; Pace N; Thomas P, 2014, 'Reply', Respirology, 19, pp. 769 - 770, http://dx.doi.org/10.1111/resp.12300
    Journal articles | 2014
    Byrne AL; Bennett M; Chatterji R; Symons R; Pace NL; Thomas PS, 2014, 'Peripheral venous and arterial blood gas analysis in adults: Are they comparable? A systematic review and meta-analysis', Respirology, 19, pp. 168 - 175, http://dx.doi.org/10.1111/resp.12225
    Journal articles | 2013
    Byrne AL; Bennett MH; Pace NL; Thomas P, 2013, 'Peripheral venous blood gas analysis versus arterial blood gas analysis for the diagnosis of respiratory failure and metabolic disturbance in adults', Cochrane Database of Systematic Reviews, 2013, http://dx.doi.org/10.1002/14651858.CD010841
    Journal articles | 2013
    Huang S; Byrne A; Dimitri A; Thomas PS, 2013, 'RESPIRATORY PRESENTATIONS OF STRONGYLOIDIASIS IN A LOW PREVALENCE SETTING', RESPIROLOGY, 18, pp. 82 - 82, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000315589700309&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2009
    Parker GB; Brotchie H, 2009, 'Reply', ACTA Psychiatrica Scandinavica, 20, pp. 503 - 503
  • Preprints | 2022
    Cysique L; Jakabek D; Bracken S; Allen-Davidian Y; Heng B; Chow S; Dehhaghi M; Pires AS; Darley D; Byrne A; Phetsouphanh C; Kelleher A; Dore G; Matthews G; Guillemin G; Brew B, 2022, Post-acute COVID-19 cognitive impairment and decline uniquely associate with kynurenine pathway activation: a longitudinal observational study, , http://dx.doi.org/10.1101/2022.06.07.22276020
    Conference Papers | 2021
    Cysique LA; Allen-Davidian Y; Darley DR; Byrne A; Wilhelm K; Dore G; Matthews G; Brew BJ, 2021, '032 Cognitive deficits are associated with anosmia but not anxio-depressive symptoms in COVID-19', in Oral abstracts, BMJ Publishing Group Ltd, presented at ANZAN Annual Scientific Meeting 2021 Abstracts, http://dx.doi.org/10.1136/bmjno-2021-anzan.32
    Conference Papers | 2012
    Byrne AL; Goldberg H; Mckenzie D, 2012, 'BRONCHOSCOPY WITH BRONCHIAL LAVAGE VERSUS SPUTUM FOR THE DIAGNOSIS OF SMEAR NEGATIVE MYCOBACTERIUM TUBERCULOSIS', in RESPIROLOGY, WILEY-BLACKWELL, pp. 83 - 83, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000301120800316&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints |
    Menzies N; Quaife M; Allwood BW; Byrne AL; Coussens AK; Harries AD; Marx FM; Meghji J; Pedrazzoli D; Salomon JA; Sweeney S; van Kampen SC; Wallis RS; Houben RMGJ; Cohen T, The Lifetime Burden of Disease Due to Incident Tuberculosis: A Global Re-Appraisal Including Post-TB Sequelae, , http://dx.doi.org/10.2139/ssrn.3944911

Past 5 Years


1) National Health & Medical Research Council Tuberculosis Centre of Research Excellence. PhD scholarship. (2014-2015).Chronic Respiratory Disease among Successfully Treated Tuberculosis Patients of Lima, Peru. Byrne AL, Marais BJ, Marks GB. $50,000.


2) National Health & Medical Research Council Tuberculosis Centre of Research Excellence. Seed Funding. (2014). Byrne AL, Marais BJ, Mitnick CD, Marks GB. Chronic airflow obstruction after successful treatment of multidrug-resistant tuberculosis. A population-based cohort study in Lima, Peru. $25,000.


3) University of Sydney Postgraduate Research Support Scheme (2014, 2015). Byrne AL. Pulmones Post TB (Lungs after tuberculosis). Project support $12,000.


4) Woolcock Institute of Medical Research Fund (2015, 2016). Byrne AL. Marais BJ, Marks GB “Pulmones Post TB” (Lungs after tuberculosis). Project support $15,000.


5) National Health & Medical Research Council Tuberculosis Centre of Research Excellence. Seed Funding. (2017). Byrne AL, Marais BJ, Marriott D. The use of therapeutic drug monitoring to improve clinical outcomes for patients with pulmonary tuberculosis; a pilot study. $25,000

Committees

1) Thoracic Society of Australia and New Zealand, New South Wales Branch. (TSANZ). Elected executive committee member. (2017-ongoing).
2) New South Wales Tuberculosis Program. Expert panel member (2017- ongoing).
3) St Vincent’s Hospital Drug Committee member (2018- ongoing).
4) The V-QUIN MDR TRIAL: Expert Panel Member to review adverse events. The V-QUIN trial is a multicentre, randomised controlled trial to assess the efficacy of 6 months of levofloxacin preventative therapy for household contacts of multidrug resistant tuberculosis patients in Vietnam.
5) St Vincent’s hospital tuberculosis working group. Founding member (2015-ongoing).

Collaborative research
Current member;

• NHMRC Tuberculosis Centre of Research Excellence • International Union Against Tuberculosis and Lung Disease

• Harvard Medical School Global Health and Social Medicine Tuberculosis Research Group

• Partners In Health (Socios En Salud Sucursal, Peru) Principal Investigator

• Associate Investigator International Research and Development (IRD; a global health delivery and research organization based in Pakistan).

Reviewer
Journals: Respirology, BMC Respiratory, International Journal of chronic obstructive pulmonary disease, Journal of Thoracic Disease & others.

My Teaching

Undergraduate, postgraduate, junior medical officer (JMO) and basic & advanced trainee teaching and supervision.

Examiner: undergraduate exams (FRACP clinical exam), ATs.

Research supervision including AT projects.