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Dr Arunasingam Abayasingam
Research Associate

Dr Arunasingam Abayasingam

BSc (Honours)

Medicine & Health
The Kirby Institute

Arun completed his Bachelor’s Degree in Science with Honours at the University of New South Wales in 2016. During his studies, he focused on pathology and pharmacology, undertaking a project investigate the effects of epidermal growth factor receptor targeted and metabolic inhibitor combination therapy in osteosarcomas.

In 2017, Arun joined the Viral Immunology Systems Program as a Postgraduate Student under the supervision of Dr Rowena Bull and Dr Chaturaka Rodrigo. His current project includes characterising Hepatitis C (HCV) Transmitted/Founder virus, understanding the host-viral interaction during acute HCV infection, and investigating the host-viral interactions in HCV re-infection. Findings of this project will potentially contribute towards designing an effective protective vaccine against HCV.
Phone
+61 (2) 9348 1583
E-mail
aabayasingam@kirby.unsw.edu.au
  • Journal articles | 2023
    2023, 'A systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA and adenovirus vectored vaccines', Cell Reports Medicine, 4, pp. 100971, http://dx.doi.org/10.1016/j.xcrm.2023.100971
    Journal articles | 2023
    2023, 'B Cell Signatures and Antibody Imprinting Define HCV Reinfection Outcome', , http://dx.doi.org/10.2139/ssrn.4418620
    Journal articles | 2022
    Adhikari A; Abayasingam A; Rodrigo C; Agapiou D; Pandzic E; Brasher NA; Fernando BSM; Keoshkerian E; Li H; Kim HN; Lord M; Popovic G; Rawlinson W; Mina M; Post JJ; Hudson B; Gilroy N; Dwyer D; Sasson SC; Grubor-Bauk B; Lloyd AR; Martinello M; Bull RA; Tedla N; Bull RA; Lloyd AR; Kaldor J; Dore G; Sorrell T; Rawlinson W; Dwyer D; Post JJ; Hudson B; Bartlett A; Lemberg D; Sasson SC; Di Girolamo N; Bull RA; Byrne M; Hammoud M; Lloyd AR; Sultan R; Post JJ; Hudson B; Gilroy N; Rawlinson W; Konecny P; Matthews G; Shek D; Holdaway S; Mitsa-Kos K; How-Chow D; Lagunday R; Robinson S; Terrill L; Joshi N; Li Y; Gill S; Sevehon A, 2022, 'Longitudinal Characterization of Phagocytic and Neutralization Functions of Anti-Spike Antibodies in Plasma of Patients after Severe Acute Respiratory Syndrome Coronavirus 2 Infection', Journal of Immunology, 209, pp. 1499 - 1512, http://dx.doi.org/10.4049/jimmunol.2200272
    Journal articles | 2022
    2022, 'SARS-CoV-2 Omicron variant escapes neutralizing antibodies and T cell responses more efficiently than other variants in mild COVID-19 convalescents', Cell Reports Medicine, 3, pp. 100651, http://dx.doi.org/10.1016/j.xcrm.2022.100651
    Journal articles | 2021
    Rouet R; Mazigi O; Walker GJ; Langley DB; Sobti M; Schofield P; Lenthall H; Jackson J; Ubiparipovic S; Henry JY; Abayasingam A; Burnett D; Kelleher A; Brink R; Bull RA; Turville S; Stewart AG; Goodnow CC; Rawlinson WD; Christ D, 2021, 'Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies', mAbs, 13, pp. 1922134, http://dx.doi.org/10.1080/19420862.2021.1922134
    Journal articles | 2021
    2021, 'Long-term persistence of RBD+ memory B cells encoding neutralizing antibodies in SARS-CoV-2 infection', Cell Reports Medicine, 2, pp. 100228, http://dx.doi.org/10.1016/j.xcrm.2021.100228
    Journal articles | 2020
    Rouet R; Mazigi O; Walker G; Langley D; Sobti M; Schofield P; Lenthall H; Jackson J; Ubiparipovic S; Henry J; Abayasingam A; Burnett D; Kelleher A; Brink R; Bull R; Turville S; Stewart A; Goodnow C; Rawlinson W; Christ D, 2020, 'Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies', , http://dx.doi.org/10.1101/2020.12.14.422791
    Journal articles | 2019
    2019, 'Clearance of hepatitis C virus is associated with early and potent but narrowly-directed, Envelope-specific antibodies', Scientific Reports, 9, pp. 13300, http://dx.doi.org/10.1038/s41598-019-49454-w
    Journal articles | 2019
    2019, 'Genomic characterization of hepatitis C virus transmitted founder variants with deep sequencing', Infection, Genetics and Evolution, 71, pp. 36 - 41, http://dx.doi.org/10.1016/j.meegid.2019.02.032
  • Preprints | 2022
    2022, A systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA (BNT162b2/mRNA-1273) and adenovirus vectored vaccines (ChAdOx1-S) after the first, second and third doses, , http://dx.doi.org/10.1101/2022.09.22.22280180
    Preprints | 2021
    2021, COVID-19 convalescents exhibit deficient humoral and T cell responses to variant of concern Spike antigens at 12 month post-infection, , http://dx.doi.org/10.1101/2021.11.08.21266035
    Preprints | 2021
    2021, Longitudinal characterisation of phagocytic and neutralisation functions of anti-Spike antibodies in plasma of patients after SARS-CoV-2 infection, , http://dx.doi.org/10.1101/2021.12.21.473774
    Preprints | 2020
    2020, Long-term persistence of neutralizing memory B cells in SARS-CoV-2, , http://dx.doi.org/10.21203/rs.3.rs-92527/v1
    Preprints |
    'One Year Later' - SARS-CoV-2-Specific Immunity in Mild Cases of COVID-19, , http://dx.doi.org/10.2139/ssrn.3859298
    Preprints |
    Long-Term Persistence of Neutralizing Memory B Cells in SARS-CoV-2, , http://dx.doi.org/10.2139/ssrn.3732365

Development of a human tonsil organoid model to study human disease. CI Abayasingam. Triple I Clinical Academic Group Seed. 2023. $75,000.