Dr Ashish Diwan
Senior Lecturer

Dr Ashish Diwan

Medicine & Health
School of Clinical Medicine

Dr Ashish Diwan is a Clinical Academic Senior Lecturer at the St George & Sutherland Clinical School, located at St George Hospital, Kogarah. 

Research Interests:

As a surgeon my research emphasis is on repair and regeneration of tissues. Degeneration of the intervertebral disc is a common problem leading to chronic back and neck pain. Understanding the molecular and mechanical basis of degeneration and/or aging of the disc is a prelude to developing strategies for disc reconstruction, repair or regeneration. I am involved in understanding the spinal column at all levels; from the molecule to biomechanics, from clinical to socio-economic impact. The role of Bone Morphogenic Proteins is being studied extensively at the bench and also in the clinic. I am involved in the development of a novel nuclear replacement device and collaborate with numerous engineers.

Broad Research Areas:
Orthopaedics, Stem Cells, Injury, Biomedical Engineering, Pain

Qualifications:
PhD, FRACS, FAOrthA

Specific Research Keywords:
Biomechanics, Spine, Back Pain, Finite element modelling (spinal column), Medical Devices, Growth Factor, Regenerative Medicine, Tissue healing, Lumbar Spine Service, Disc Degeneratio

Phone
+61 2 8566 7166
  • Book Chapters | 2021
    Umali J; Ghahreman A; Diwan AD, 2021, 'Spinal Fusion Evaluation in Various Settings: A Summary of Human-Only Studies', in Handbook of Spine Technology, Springer International Publishing, pp. 1131 - 1147, http://dx.doi.org/10.1007/978-3-319-44424-6_123
    Book Chapters | 2019
    Chamoli U; Lam M; Diwan AD, 2019, 'Replacing the Nucleus Pulposus for Degenerative Disc Disease and Disc Herniation: Disc Preservation Following Discectomy', in Handbook of Spine Technology, Springer International Publishing, pp. 1 - 20, http://dx.doi.org/10.1007/978-3-319-33037-2_94-1
    Book Chapters | 2019
    Umali J; Ghahreman A; Diwan A, 2019, 'Spinal Fusion Evaluation in Various Settings: A Summary of Human-Only Studies', in Handbook of Spine Technology, Springer International Publishing, pp. 1 - 17, http://dx.doi.org/10.1007/978-3-319-33037-2_123-1
  • Journal articles | 2023
    Chen X; Kohan S; Bhargav D; Choi J; Perera S; Dean C; Chopra N; Sial A; Sandhu HS; Apos E; Appleyard R; Diwan AD, 2023, 'Phase 1 evaluation of an elastomeric nucleus pulposus device as an option to augment disc at microdiscectomy: Experimental results from biomechanical and biocompatibility testing and first in human', JOR Spine, http://dx.doi.org/10.1002/jsp2.1250
    Journal articles | 2023
    Chen X; Lu S; Chopra N; Cui P; Zhang S; Narulla R; Diwan AD, 2023, 'The association between low virulence organisms in different locations and intervertebral disc structural failure: A meta-analysis and systematic review', JOR Spine, http://dx.doi.org/10.1002/jsp2.1244
    Journal articles | 2023
    Chew G; Menounos S; Sheldrick K; Das A; Diwan AD, 2023, 'Age-based exclusion is common and multifactorial in spinal RCTs: a systematic review and quantitative analysis', European Spine Journal, http://dx.doi.org/10.1007/s00586-023-07618-3
    Journal articles | 2023
    Ramakrishna VAS; Chamoli U; Larosa AG; Mukhopadhyay SC; Gangadhara Prusty B; Diwan AD, 2023, 'A biomechanical comparison of posterior fixation approaches in lumbar fusion using computed tomography based lumbosacral spine modelling', Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, pp. 9544119221149119, http://dx.doi.org/10.1177/09544119221149119
    Journal articles | 2023
    Ramakrishna VAS; Chamoli U; Mukhopadhyay SC; Diwan AD; Prusty BG, 2023, 'Measuring compressive loads on a ‘smart’ lumbar interbody fusion cage: Proof of concept', Journal of Biomechanics, vol. 147, pp. 111440, http://dx.doi.org/10.1016/j.jbiomech.2023.111440
    Journal articles | 2022
    Belavy DL; Tagliaferri SD; Buntine P; Saueressig T; Ehrenbrusthoff K; Chen X; Diwan A; Miller CT; Owen PJ, 2022, 'Interventions for promoting evidence-based guideline-consistent surgery in low back pain: a systematic review and meta-analysis of randomised controlled trials', European Spine Journal, vol. 31, pp. 2851 - 2865, http://dx.doi.org/10.1007/s00586-022-07378-6
    Journal articles | 2022
    Chen X; Sial A; Stewart C; Vargas Castillo J; Diwan AD, 2022, 'Stand-alone anterior cervical decompression and fusion surgery: A cohort study evaluating a shaped cage without plates or screws', Frontiers in Surgery, vol. 9, http://dx.doi.org/10.3389/fsurg.2022.934018
    Journal articles | 2022
    Chen X; Sima S; Sandhu HS; Kuan J; Diwan AD, 2022, 'Radiographic evaluation of lumbar intervertebral disc height index: An intra and inter-rater agreement and reliability study', Journal of Clinical Neuroscience, vol. 103, pp. 153 - 162, http://dx.doi.org/10.1016/j.jocn.2022.07.018
    Journal articles | 2022
    Chepurin D; Chamoli U; Diwan AD, 2022, 'Bony Stress and Its Association With Intervertebral Disc Degeneration in the Lumbar Spine: A Systematic Review of Clinical and Basic Science Studies', Global Spine Journal, vol. 12, pp. 964 - 979, http://dx.doi.org/10.1177/21925682211008837
    Journal articles | 2022
    He B; Sheldrick K; Das A; Diwan A, 2022, 'Clinical and Research MRI Techniques for Assessing Spinal Cord Integrity in Degenerative Cervical Myelopathy—A Scoping Review', Biomedicines, vol. 10, pp. 2621 - 2621, http://dx.doi.org/10.3390/biomedicines10102621
    Journal articles | 2022
    Li W; Lai K; Chopra N; Zheng Z; Das A; Diwan AD, 2022, 'Gut-disc axis: A cause of intervertebral disc degeneration and low back pain?', European Spine Journal, vol. 31, pp. 917 - 925, http://dx.doi.org/10.1007/s00586-022-07152-8
    Journal articles | 2022
    MacDessi SJ; Wood JA; Diwan A; Harris IA, 2022, 'Intraoperative pressure sensors improve soft-tissue balance but not clinical outcomes in total knee arthroplasty: a multicentre randomized controlled trial', The bone & joint journal, vol. 104-B, pp. 604 - 612, http://dx.doi.org/10.1302/0301-620X.104B5.BJJ-2021-1299.R2
    Journal articles | 2022
    Mesregah MK; Yoshida B; Lashkari N; Abedi A; Meisel HJ; Diwan A; Hsieh P; Wang JC; Buser Z; Yoon ST, 2022, 'Demographic, clinical, and operative risk factors associated with postoperative adjacent segment disease in patients undergoing lumbar spine fusions: a systematic review and meta-analysis', Spine Journal, vol. 22, pp. 1038 - 1069, http://dx.doi.org/10.1016/j.spinee.2021.12.002
    Journal articles | 2022
    Ramakrishna VAS; Chamoli U; Larosa AG; Mukhopadhyay SC; Prusty BG; Diwan AD, 2022, 'Finite element modeling of temporal bone graft changes in XLIF: Quantifying biomechanical effects at adjacent levels', Journal of Orthopaedic Research, vol. 40, pp. 1420 - 1435, http://dx.doi.org/10.1002/jor.25166
    Journal articles | 2022
    Tu J; Li W; Yang S; Yang P; Yan Q; Wang S; Lai K; Bai X; Wu C; Ding W; Cooper-White J; Diwan A; Yang C; Yang H; Zou J, 2022, 'Single-Cell Transcriptome Profiling Reveals Multicellular Ecosystem of Nucleus Pulposus during Degeneration Progression', Advanced Science, vol. 9, pp. e2103631, http://dx.doi.org/10.1002/advs.202103631
    Journal articles | 2021
    Belavy DL; Diwan AD; Ford J; Miller CT; Hahne AJ; Mundell N; Tagliaferri S; Bowe S; Pedder H; Saueressig T; Zhao X; Chen X; Balasundaram AP; Arora NK; Owen PJ, 2021, 'Network meta-analysis for comparative effectiveness of treatments for chronic low back pain disorders: Systematic review protocol', BMJ Open, vol. 11, http://dx.doi.org/10.1136/bmjopen-2021-057112
    Journal articles | 2021
    Chen X; Hodges PW; James G; Diwan AD, 2021, 'Do markers of inflammation and/or muscle regeneration in lumbar multifidus muscle and fat differ between individuals with good or poor outcome following microdiscectomy for lumbar disc herniation?', Spine, vol. 46, pp. 678 - 686, http://dx.doi.org/10.1097/BRS.0000000000003863
    Journal articles | 2021
    Chen X; Sandhu HS; Vargas Castillo J; Diwan AD, 2021, 'The association between pain scores and disc height change following discectomy surgery in lumbar disc herniation patients: a systematic review and meta-analysis', European Spine Journal, vol. 30, pp. 3265 - 3277, http://dx.doi.org/10.1007/s00586-021-06891-4
    Journal articles | 2021
    Chopra N; Menounos S; Choi JP; Hansbro PM; Diwan AD; Das A, 2021, 'Blood-Spinal Cord Barrier: Its Role in Spinal Disorders and Emerging Therapeutic Strategies', NeuroSci, vol. 3, pp. 1 - 27, http://dx.doi.org/10.3390/neurosci3010001
    Journal articles | 2021
    Cui H; Zhang J; Li Z; Chen F; Cui H; Du X; Liu H; Wang J; Diwan AD; Zheng Z, 2021, 'Growth differentiation factor-6 attenuates inflammatory and pain-related factors and degenerated disc-induced pain behaviors in rat model', Journal of Orthopaedic Research, vol. 39, pp. 959 - 970, http://dx.doi.org/10.1002/jor.24793
    Journal articles | 2021
    James G; Chen X; Diwan A; Hodges PW, 2021, 'Fat infiltration in the multifidus muscle is related to inflammatory cytokine expression in the muscle and epidural adipose tissue in individuals undergoing surgery for intervertebral disc herniation', European Spine Journal, vol. 30, pp. 837 - 845, http://dx.doi.org/10.1007/s00586-020-06514-4
    Journal articles | 2021
    Koremans FW; Chen X; Das A; Diwan AD, 2021, 'Changes in back pain scores after bariatric surgery in obese patients: A systematic review and meta-analysis', Journal of Clinical Medicine, vol. 10, http://dx.doi.org/10.3390/jcm10071443
    Journal articles | 2021
    Lapkin S; Ellwood L; Diwan A; Fernandez R, 2021, 'Reliability, validity, and responsiveness of multidimensional pain assessment tools used in postoperative adult patients: A systematic review of measurement properties', JBI Evidence Synthesis, vol. 19, pp. 284 - 307, http://dx.doi.org/10.11124/JBISRIR-D-19-00407
    Journal articles | 2021
    MacDessi SJ; Cohen DA; Wood JA; Diwan AD; Harris IA, 2021, 'Does the Use of Intraoperative Pressure Sensors for Knee Balancing in Total Knee Arthroplasty Improve Clinical Outcomes? A Comparative Study With a Minimum Two-Year Follow-Up', Journal of Arthroplasty, vol. 36, pp. 514 - 519, http://dx.doi.org/10.1016/j.arth.2020.08.025
    Journal articles | 2021
    MacDessi SJ; Wood JA; Diwan AD; Harris IA; Bhimani A; Burns AWR; Chen DB; Molnar RB; Mulford JS; Walker RM, 2021, 'Surgeon-defined assessment is a poor predictor of knee balance in total knee arthroplasty: a prospective, multicenter study', Knee Surgery, Sports Traumatology, Arthroscopy, vol. 29, pp. 498 - 506, http://dx.doi.org/10.1007/s00167-020-05925-6
    Journal articles | 2021
    Menounos S; Hansbro PM; Diwan AD; Das A, 2021, 'Pathophysiological Correlation between Cigarette Smoking and Amyotrophic Lateral Sclerosis', NeuroSci, vol. 2, pp. 120 - 134, http://dx.doi.org/10.3390/neurosci2020008
    Journal articles | 2021
    Tu J; Castillo JV; Das A; Diwan AD, 2021, 'Degenerative cervical myelopathy: Insights into its pathobiology and molecular mechanisms', Journal of Clinical Medicine, vol. 10, pp. 1 - 28, http://dx.doi.org/10.3390/jcm10061214
    Journal articles | 2021
    Tu J; Li W; Yang S; Yang P; Yan Q; Wang S; Lai K; Bai X; Wu C; Ding W; Cooper-White J; Diwan A; Yang C; Yang H; Zou J, 2021, 'Single-cell transcriptome profiling reveals multicellular ecosystem of nucleus pulposus during degeneration progression', , http://dx.doi.org/10.1101/2021.05.25.445620
    Journal articles | 2020
    Chamoli U; Umali J; Kleuskens MWA; Chepurin D; Diwan AD, 2020, 'Morphological characteristics of the kangaroo lumbar intervertebral discs and comparison with other animal models used in spine research', European Spine Journal, vol. 29, pp. 652 - 662, http://dx.doi.org/10.1007/s00586-019-06044-8
    Journal articles | 2020
    Chen X; Chamoli U; Vargas Castillo J; Ramakrishna VAS; Diwan AD, 2020, 'Complication rates of different discectomy techniques for symptomatic lumbar disc herniation: a systematic review and meta-analysis', European Spine Journal, vol. 29, pp. 1752 - 1770, http://dx.doi.org/10.1007/s00586-020-06389-5
    Journal articles | 2020
    Hodgkinson T; Gilbert HTJ; Pandya T; Diwan AD; Hoyland JA; Richardson SM, 2020, 'Regenerative response of degenerate human nucleus pulposus cells to GDF6 stimulation', International Journal of Molecular Sciences, vol. 21, pp. 1 - 14, http://dx.doi.org/10.3390/ijms21197143
    Journal articles | 2020
    Koremans FW; Chen X; Das A; Diwan AD, 2020, 'Changes in back pain scores after bariatric surgery in obese patients: A systematic review and meta-analysis', , http://dx.doi.org/10.1101/2020.08.25.20182022
    Journal articles | 2020
    MacDessi SJ; Griffiths-Jones W; Chen DB; Griffiths-Jones S; Wood JA; Diwan AD; Harris IA, 2020, 'Restoring the constitutional alignment with a restrictive kinematic protocol improves quantitative soft-tissue balance in total knee arthroplasty: A randomized controlled trial', Bone and Joint Journal, vol. 102, pp. 117 - 124, http://dx.doi.org/10.1302/0301-620X.102B1.BJJ-2019-0674.R2
    Journal articles | 2020
    Ramakrishna VAS; Chamoli U; Rajan G; Mukhopadhyay SC; Prusty BG; Diwan AD, 2020, 'Smart orthopaedic implants: A targeted approach for continuous postoperative evaluation in the spine', Journal of Biomechanics, vol. 104, pp. 109690 - 109690, http://dx.doi.org/10.1016/j.jbiomech.2020.109690
    Journal articles | 2020
    Sritharan K; Chamoli U; Kuan J; Diwan AD, 2020, 'Assessment of degenerative cervical stenosis on T2-weighted MR imaging: sensitivity to change and reliability of mid-sagittal and axial plane metrics', Spinal Cord, vol. 58, pp. 238 - 246, http://dx.doi.org/10.1038/s41393-019-0358-1
    Journal articles | 2020
    Tavakoli J; Diwan AD; Tipper JL, 2020, 'Advanced strategies for the regeneration of lumbar disc annulus fibrosus', International Journal of Molecular Sciences, vol. 21, pp. 1 - 20, http://dx.doi.org/10.3390/ijms21144889
    Journal articles | 2020
    Tavakoli J; Diwan AD; Tipper JL, 2020, 'Elastic fibers: The missing key to improve engineering concepts for reconstruction of the Nucleus Pulposus in the intervertebral disc', Acta Biomaterialia, http://dx.doi.org/10.1016/j.actbio.2020.06.008
    Journal articles | 2020
    Tavakoli J; Diwan AD; Tipper JL, 2020, 'The ultrastructural organization of elastic fibers at the interface of the nucleus and annulus of the intervertebral disk', Acta Biomaterialia, vol. 114, pp. 323 - 332, http://dx.doi.org/10.1016/j.actbio.2020.07.021
    Journal articles | 2020
    Zhang T; Ren X; Feng X; Diwan A; Luk KDK; Lu WW; Wong TM; Li C; Cheung JPY, 2020, 'Failure mechanisms of pedicle screws and cortical screws fixation under large displacement: A biomechanical and microstructural study based on a clinical case scenario', Journal of the Mechanical Behavior of Biomedical Materials, vol. 104, http://dx.doi.org/10.1016/j.jmbbm.2020.103646
    Journal articles | 2020
    Zhang T; Zhu C; Lu Q; Liu J; Diwan A; Cheung JPY, 2020, 'A novel tool to provide predictable alignment data irrespective of source and image quality acquired on mobile phones: what engineers can offer clinicians', European Spine Journal, vol. 29, pp. 387 - 395, http://dx.doi.org/10.1007/s00586-019-06264-y
    Journal articles | 2019
    Chen X; Chamoli U; Lapkin S; Castillo JV; Diwan AD, 2019, 'Complication rates of different discectomy techniques for the treatment of lumbar disc herniation: a network meta-analysis', European Spine Journal, vol. 28, pp. 2588 - 2601, http://dx.doi.org/10.1007/s00586-019-06142-7
    Journal articles | 2019
    Chepurin D; Chamoli U; Sheldrick K; Lapkin S; Scott D; Kuan J; Diwan AD, 2019, 'Bony stress in the lumbar spine is associated with intervertebral disc degeneration and low back pain: a retrospective case–control MRI study of patients under 25 years of age', European Spine Journal, vol. 28, pp. 2470 - 2477, http://dx.doi.org/10.1007/s00586-019-06148-1
    Journal articles | 2019
    Costa N; Ferreira ML; Setchell J; Makovey J; Dekroo T; Downie A; Diwan A; Koes B; Natvig B; Vicenzino B; Hunter D; Roseen EJ; Rasmussen-Barr E; Guillemin F; Hartvigsen J; Bennell K; Costa L; Macedo L; Pinheiro M; Underwood M; Van Tulder M; Johansson M; Enthoven P; Kent P; O'Sullivan P; Suri P; Genevay S; Hodges PW, 2019, 'A Definition of “Flare” in Low Back Pain: A Multiphase Process Involving Perspectives of Individuals With Low Back Pain and Expert Consensus', Journal of Pain, vol. 20, pp. 1267 - 1275, http://dx.doi.org/10.1016/j.jpain.2019.03.009
    Journal articles | 2019
    Hodgkinson T; Shen B; Diwan A; Hoyland JA; Richardson SM, 2019, 'Therapeutic potential of growth differentiation factors in the treatment of degenerative disc diseases', JOR Spine, vol. 2, http://dx.doi.org/10.1002/jsp2.1045
    Journal articles | 2019
    Lapkin S; Fernandez R; Ellwood L; Diwan A, 2019, 'Reliability, validity and generalizability of multidimensional pain assessment tools used in postoperative adult patients: a systematic review protocol', JBI database of systematic reviews and implementation reports, vol. 17, pp. 1334 - 1340, http://dx.doi.org/10.11124/JBISRIR-2017-003819
    Journal articles | 2019
    MacDessi SJ; Bhimani A; Burns AWR; Chen DB; Leong AKL; Molnar RB; Mulford JS; Walker RM; Harris IA; Diwan A; Wood JA, 2019, 'Does soft tissue balancing using intraoperative pressure sensors improve clinical outcomes in total knee arthroplasty? A protocol of a multicentre randomised controlled trial', BMJ Open, vol. 9, pp. e027812, http://dx.doi.org/10.1136/bmjopen-2018-027812
    Journal articles | 2019
    Sheldrick K; Chamoli U; Masuda K; Miyazaki S; Kato K; Diwan AD, 2019, 'A novel magnetic resonance imaging postprocessing technique for the assessment of intervertebral disc degeneration—Correlation with histological grading in a rabbit disc degeneration model', JOR Spine, vol. 2, http://dx.doi.org/10.1002/jsp2.1060
    Journal articles | 2018
    Bax DV; Yin Y; Kondyurin A; Diwan AD; Bhargav D; Weiss AS; Bilek MMM; McKenzie DR, 2018, 'Plasma processing of PDMS based spinal implants for covalent protein immobilization, cell attachment and spreading', Journal of Materials Science: Materials in Medicine, vol. 29, http://dx.doi.org/10.1007/s10856-018-6181-y
    Journal articles | 2018
    Choy WJ; Phan K; Diwan AD; Ong CS; Mobbs RJ, 2018, 'Annular closure device for disc herniation: Meta-analysis of clinical outcome and complications', BMC Musculoskeletal Disorders, vol. 19, http://dx.doi.org/10.1186/s12891-018-2213-5
    Journal articles | 2018
    Martin JT; Gullbrand SE; Fields AJ; Purmessur D; Diwan AD; Oxland TR; Chiba K; Guilak F; Hoyland JA; Iatridis JC, 2018, 'Publication trends in spine research from 2007 to 2016: Comparison of the Orthopaedic Research Society Spine Section and the International Society for the Study of the Lumbar Spine', JOR Spine, vol. 1, http://dx.doi.org/10.1002/jsp2.1006
    Journal articles | 2018
    Miyazaki S; Diwan AD; Kato K; Cheng K; Bae WC; Sun Y; Yamada J; Muehleman C; Lenz ME; Inoue N; Sah RL; Kawakami M; Masuda K, 2018, 'ISSLS PRIZE IN BASIC SCIENCE 2018: Growth differentiation factor-6 attenuated pro-inflammatory molecular changes in the rabbit anular-puncture model and degenerated disc-induced pain generation in the rat xenograft radiculopathy model', European Spine Journal, vol. 27, pp. 739 - 751, http://dx.doi.org/10.1007/s00586-018-5488-1
    Journal articles | 2018
    Ramakrishna VAS; Chamoli U; Viglione LL; Tsafnat N; Diwan AD, 2018, 'Mild (not severe) disc degeneration is implicated in the progression of bilateral L5 spondylolysis to spondylolisthesis', BMC Musculoskeletal Disorders, vol. 19, http://dx.doi.org/10.1186/s12891-018-2011-0
    Journal articles | 2018
    Ramakrishna VAS; Chamoli U; Viglione LL; Tsafnat N; Diwan AD, 2018, 'The Role of Sacral Slope in the Progression of a Bilateral Spondylolytic Defect at L5 to Spondylolisthesis: A Biomechanical Investigation Using Finite Element Analysis', Global Spine Journal, vol. 8, pp. 460 - 470, http://dx.doi.org/10.1177/2192568217735802
    Journal articles | 2018
    Richardson SM; Hodgkinson T; Wei A; Shen B; Diwan A; Hoyland J, 2018, 'Growth differentiation factor 6 promotes a healthy nucleus pulposus cell phenotype through smad and smad-independent signalling pathways', Osteoarthritis and Cartilage, vol. 26, pp. S423 - S423, http://dx.doi.org/10.1016/j.joca.2018.02.817
    Journal articles | 2018
    Sabnis AB; Chamoli U; Diwan AD, 2018, 'Is L5–S1 motion segment different from the rest? A radiographic kinematic assessment of 72 patients with chronic low back pain', European Spine Journal, vol. 27, pp. 1127 - 1135, http://dx.doi.org/10.1007/s00586-017-5400-4
    Journal articles | 2018
    Thorpe AA; Bach FC; Tryfonidou MA; Le Maitre CL; Mwale F; Diwan AD; Ito K, 2018, 'Leaping the hurdles in developing regenerative treatments for the intervertebral disc from preclinical to clinical', JOR Spine, vol. 1, http://dx.doi.org/10.1002/jsp2.1027
    Journal articles | 2017
    Viglione LL; Chamoli U; Diwan AD, 2017, 'Is Stand-Alone Anterior Lumbar Interbody Fusion a Safe and Efficacious Treatment for Isthmic Spondylolisthesis of L5-S1?', Global Spine Journal, vol. 7, pp. 587 - 595, http://dx.doi.org/10.1177/2192568217699210
    Journal articles | 2017
    Virk SS; Diwan A; Phillips FM; Sandhu H; Khan SN, 2017, 'What is the Rate of Revision Discectomies After Primary Discectomy on a National Scale?', Clinical Orthopaedics and Related Research, vol. 475, pp. 2752 - 2762, http://dx.doi.org/10.1007/s11999-017-5467-6
    Journal articles | 2016
    Wei A; Shen B; Williams LA; Bhargav D; Gulati T; Fang Z; Pathmanandavel S; Diwan AD, 2016, 'Expression of growth differentiation factor 6 in the human developing fetal spine retreats from vertebral ossifying regions and is restricted to cartilaginous tissues', Journal of Orthopaedic Research, vol. 34, pp. 279 - 289, http://dx.doi.org/10.1002/jor.22983
    Journal articles | 2016
    Wei A; Shen B; Williams LA; Bhargav D; Yan F; Chong BH; Diwan AD, 2016, 'Expression and functional roles of estrogen receptor GPR30 in human intervertebral disc', Journal of Steroid Biochemistry and Molecular Biology, vol. 158, pp. 46 - 55, http://dx.doi.org/10.1016/j.jsbmb.2016.01.012
    Journal articles | 2015
    Chamoli U; Korkusuz MH; Sabnis AB; Manolescu AR; Tsafnat N; Diwan AD, 2015, 'Global and segmental kinematic changes following sequential resection of posterior osteoligamentous structures in the lumbar spine: An in vitro biomechanical investigation using pure moment testing protocols', Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, vol. 229, pp. 812 - 821, http://dx.doi.org/10.1177/0954411915612503
    Journal articles | 2015
    Diwan AD; Shen B; Wei A; Williams L; Zhou F, 2015, 'Cartilage Derived Morphogenetic Protein-2 Induces Cell Migration and Its Chondrogenic Potential in C28/I2 Cells', International Journal of Spine Surgery, vol. 9, pp. 1 - 13, http://dx.doi.org/10.14444/2052
    Journal articles | 2015
    Gulati T; Chung SA; Wei AQ; Diwan AD, 2015, 'Localization of bone morphogenetic protein 13 in human intervertebral disc and its molecular and functional effects in vitro in 3D culture', Journal of Orthopaedic Research, vol. 33, pp. 1769 - 1775, http://dx.doi.org/10.1002/jor.22965
    Journal articles | 2014
    Arora M; Diwan AD; Harris IA, 2014, 'Prevalence and factors of burnout among Australian orthopaedic trainees: A cross-sectional study', Journal of Orthopaedic Surgery, vol. 22, pp. 374 - 377, http://dx.doi.org/10.1177/230949901402200322
    Journal articles | 2014
    Chamoli U; Chen AS; Diwan AD, 2014, 'Interpedicular kinematics in an in vitro biomechanical assessment of a bilateral lumbar spondylolytic defect', Clinical Biomechanics, vol. 29, pp. 1108 - 1115, http://dx.doi.org/10.1016/j.clinbiomech.2014.10.002
    Journal articles | 2014
    Chamoli U; Chen AS; Diwan AD, 2014, 'To the editor', Spine, vol. 39, pp. 921, http://dx.doi.org/10.1097/BRS.0000000000000310
    Journal articles | 2014
    Chamoli U; Diwan AD; Tsafnat N, 2014, 'Pedicle screw-based posterior dynamic stabilizers for degenerative spine: In vitro biomechanical testing and clinical outcomes', Journal of Biomedical Materials Research - Part A, vol. 102, pp. 3324 - 3340, http://dx.doi.org/10.1002/jbm.a.34986
    Journal articles | 2014
    Grigg M; Arora M; Diwan AD, 2014, 'Australian medical students and their choice of surgery as a career: a review', ANZ journal of surgery, vol. 84, pp. 653 - 655, http://dx.doi.org/10.1111/ans.12389
    Journal articles | 2014
    Grigg M; Arora M; Diwan AD, 2014, 'Role of nutritional supplementation in elderly patients with hip fractures', Journal of Orthopaedic Translation, vol. 2, pp. 26 - 34, http://dx.doi.org/10.1016/j.jot.2013.11.003
    Journal articles | 2014
    Malham G; Parker R; Ballok Z; Goss B; Diwan A; Uribe J; Malham G; Parker R; Ballok Z; Goss B; Diwan A, 2014, 'Bone Scans Are Reliable for the Identification of Lumbar Disk and Facet Pathology', Global Spine Journal, vol. 5, pp. 23 - 29, http://dx.doi.org/10.1055/s-0034-1394298
    Journal articles | 2014
    Sabnis A; Diwan A, 2014, 'The timing of surgery in lumbar disc prolapse: A systematic review', Indian Journal of Orthopaedics, vol. 48, pp. 127 - 135, http://dx.doi.org/10.4103/0019-5413.128740
    Journal articles | 2014
    Wei A; Shen B; Williams L; Diwan AD, 2014, 'Mesenchymal Stem Cells: Potential application in intervertebral disc regeneration', Translational Pediatrics, vol. 3, pp. 71 - 90, http://dx.doi.org/10.3978/j.issn.2224-4336.2014.03.05
    Journal articles | 2013
    Arora M; Asha S; Chinnappa J; Diwan AD, 2013, 'Review article: Burnout in emergency medicine physicians', EMA - Emergency Medicine Australasia, vol. 25, pp. 491 - 495, http://dx.doi.org/10.1111/1742-6723.12135
    Journal articles | 2013
    Arora M; Chan E; Gupta S; Diwan AD, 2013, 'Polymethylmethacrylate bone cements and additives: A review of the literature', World Journal of Orthopedics, vol. 4, pp. 67 - 74, http://dx.doi.org/10.5312/wjo.v4.i2.67
    Journal articles | 2013
    Diwan AD; Leong A; Appleyard R; Bhargav D; Fang Z; Wei A, 2013, 'Bone morphogenetic protein-7 accelerates fracture healing in osteoporotic rats', Indian Journal of Orthopaedics, vol. 47, pp. 540 - 546, http://dx.doi.org/10.4103/0019-5413.121569
    Journal articles | 2013
    Mathew J; Singh SB; Garis S; Diwan AD, 2013, 'Backing up the stories: The psychological and social costs of chronic low-back pain', International Journal of Spine Surgery, vol. 7, http://dx.doi.org/10.1016/j.ijsp.2013.02.001
    Journal articles | 2013
    Oliver RA; Yu Y; Yee G; Low AK; Diwan AD; Walsh WR, 2013, 'Poor histological healing of a femoral fracture following 12 months of oestrogen deficiency in rats', Osteoporosis International, vol. 24, pp. 2581 - 2589, http://dx.doi.org/10.1007/s00198-013-2345-2
    Journal articles | 2013
    Zhou FY; Wei AIQ; Diwan A, 2013, 'An overview of intervertebral disc degeneration therapies and an evaluation of the chondrogenic and chemotactic potential of CDMP-2', Journal of Biomimetics, Biomaterials, and Tissue Engineering, vol. 18, pp. 97 - 118, http://dx.doi.org/10.4028/www.scientific.net/JBBTE.18.97
    Journal articles | 2012
    Kishen T; Lindstrom ST; Etherington G; Diwan AD, 2012, 'Veillonella spondylodiscitis in a healthy 76-year-old lady', European Spine Journal, vol. 21, pp. S413 - S417, http://dx.doi.org/10.1007/s00586-011-1871-x
    Journal articles | 2012
    Mitchell SJ; Hilmer SN; Kirkpatrick CM; Hansen R; Williamson DA; Singh N; Finnegan T; Allen BJ; Diamond T; Diwan AD; Lloyd BD; Smith E; Fiatarone Singh M, 2012, 'Estimation of lean body weight in older women with hip fracture', The Journal of Nutrition, Health and Aging (JNHA), vol. 16, pp. 188 - 192, http://dx.doi.org/10.1007/s12603-011-0100-y
    Journal articles | 2011
    Brisby H; Wei AY; Chung S; Tao H; Ma D; Diwan A, 2011, 'Survival and differentiation of syngeneic bone marrow-derived mononuclear cells in rat intervertebral discs', Stem Cell Therapy and Uses in Medical Treatment, pp. 23 - 34
    Journal articles | 2011
    Sabet TS; Ho R; Choi J; Boughton PC; Diwan AD, 2011, 'A kangaroo spine lumbar motion segment model: Biomechanical analysis of a novel in-situ curing nucleus replacement device', Journal of Biomimetics, Biomaterials, and Tissue Engineering, vol. 9, pp. 25 - 35, http://dx.doi.org/10.4028/www.scientific.net/JBBTE.9.25
    Journal articles | 2010
    Boughton P; Merhebi J; Kim C; Roger G; Diwan A; Clarke E; Amanat N; Ho R; Ruys A, 2010, 'An interlocking ligamentous spinal disk arthroplasty with neural network infrastructure', Journal of Biomimetics, Biomaterials, and Tissue Engineering, vol. 7, pp. 55 - 79, http://dx.doi.org/10.4028/www.scientific.net/JBBTE.7.55
    Journal articles | 2010
    Brisby H; Wei A; Molloy TJ; Chung S; Murrell GA; Diwan AD, 2010, 'The effect of running exercise on intervertebral disc extracellular matrix production in a rat model.', Spine, vol. 35, pp. 1429 - 1436, http://dx.doi.org/10.1097/BRS.0b013e3181e0f5bc
    Journal articles | 2010
    Shen B; Wei A; Bhargav D; Kishen T; Diwan AD, 2010, 'Hyaluronan: its potential application in intervertebral disc regeneration', Orthopedic research and reviews, vol. 2, pp. 17 - 26, http://dx.doi.org/10.2147/ORR.S7741
    Journal articles | 2010
    Shen B; Wei A; Whittaker S; Williams LA; Tao H; Ma DD; Diwan AD, 2010, 'The Role of BMP-7 in Chondrogenic and Osteogenic Differentiation of Human Bone Marrow Multipotent Mesenchymal Stromal Cells in vitro', Journal of Cellular Biochemistry, vol. 109, pp. 406 - 416, http://dx.doi.org/10.1002/jcb.22412
    Journal articles | 2010
    Strange DGT; Fisher ST; Boughton P; Kishen T; Diwan AD, 2010, 'Restoration of compressive loading properties of lumbar discs with a nucleus implant-a finite element analysis study', Spine Journal, vol. 10, pp. 602 - 609, http://dx.doi.org/10.1016/j.spinee.2010.04.015
    Journal articles | 2010
    Wei A; Brisby H; Hoy IM; Chung S; Murrell G; Diwan A, 2010, 'The effect of running exercise on intervertebral disc extracellular matrix production in a rat model', Journal of Science and Medicine in Sport, vol. 12, pp. e176 - e177, http://dx.doi.org/10.1016/j.jsams.2009.10.372
    Journal articles | 2010
    Wei A; Leong AK; Williams LA; Chung S; Shen B; Bhargav D; Diwan AD, 2010, 'BMP-7 in combination with estrogen enhances bone formation in a fracture callus explant culture.', Tohoku Journal of Experimental Medicine, vol. 221, pp. 61 - 68, http://dx.doi.org/10.1620/tjem.221.61
    Journal articles | 2009
    Fiatarone-Singh M; Singh N; Hansen RD; Finnegan T; Allen BJ; Diamond T; Diwan AD; Lloyd BD; Williamson D; Smith E; Grady J; Stavrinos T; Thompson M, 2009, 'Methodology and baseline characteristics for the sarcopenia and hip fracture study: A 5-year prospective study', Journals of Gerontology, Series A : Biological Sciences and Medical Sciences, vol. 64, pp. 568 - 574, http://dx.doi.org/10.1093/gerona/glp002
    Journal articles | 2009
    Lloyd BD; Williamson DA; Singh N; Hansen R; Diamond T; Finnegan T; Allen BJ; Grady J; Stavrinos T; Smith EU; Diwan AD; Singh M, 2009, 'Recurrent and injurious falls in the year following hip fracture: A prospective study of incidence and risk factors from the sarcopenia and hip fracture study', Journals of Gerontology, Series A : Biological Sciences and Medical Sciences, vol. 64A, pp. 599 - 609, http://dx.doi.org/10.1093/gerona/glp003
    Journal articles | 2009
    Shen B; Wei A; Tao H; Diwan AD; Ma DD, 2009, 'BMP-2 enhances TGF-β3-mediated chondrogenic differentiation of human bone marrow multipotent mesenchymal stromal cells in alginate bead culture', Tissue Engineering: Part A, vol. 15, pp. 1311 - 1320, http://dx.doi.org/10.1089/ten.tea.2008.0132
    Journal articles | 2009
    Wei A-Q; Brisby H; Molloy T; Chung SA; Murrell G; Diwan A, 2009, '28. The Effects of Running on Intervertebral Disc Extracellular Matrix Production in Rats', The Spine Journal, vol. 9, pp. 15S - 16S, http://dx.doi.org/10.1016/j.spinee.2009.08.035
    Journal articles | 2009
    Wei A; Bhargav D; Shen B; Kishen T; Duffy N; Diwan AD, 2009, 'BMP13 prevents the effects of annular injury in an ovine model', International Journal of Biological Sciences, vol. 5, pp. 388 - 396, http://dx.doi.org/10.7150/ijbs.5.388
    Journal articles | 2009
    Wei A; Chung S; Tao H; Brisby H; Lin Z; Shen B; Ma DD; Diwan AD, 2009, 'Differentiation of rodent bone marrow mesenchymal stem cells into intervertebral disc-like cells following coculture with rat disc tissue', Tissue Engineering: Part A, vol. 15, pp. 2581 - 2593, http://dx.doi.org/10.1089/ten.tea.2008.0458
    Journal articles | 2009
    Wei A; Tao H; Chung S; Brisby H; Ma DD; Diwan AD, 2009, 'The fate of transplanted xenogeneic bone marrow-derived stem cells in rat intervertebral discs', Journal of Orthopaedic Research, vol. 27, pp. 374 - 379, http://dx.doi.org/10.1002/jor.20567
    Journal articles | 2008
    Lu J; Bhargav D; Wei A; Diwan AD, 2008, 'Posterolateral intertransverse spinal fusion possible in osteoporotic rats with BMP-7 in a higher dose delivered on a composite carrier', Spine, vol. 33, pp. 242 - 249, http://dx.doi.org/10.1097/BRS.0b013e318162451b
    Journal articles | 2008
    Tassabehji M; Fang ZM; McGaughran J; Zhao Z; De Bock CE; Howard E; Malass M; Donnai D; Diwan AD; Manson FD; Murrell DF; Clarke RA, 2008, 'Mutations in GDF6 are associated with vertebral segmentation defects in klippel-feil syndrome', Human Mutation, vol. 29, pp. 1017 - 1027, http://dx.doi.org/10.1002/humu.20741
    Journal articles | 2008
    Wei A; Brisby H; Chung S; Diwan AD, 2008, 'Bone morphogenetic protein-7 protects human intervertebral disc cells in vitro from apoptosis', Spine Journal, vol. 8, pp. 466 - 474, http://dx.doi.org/10.1016/j.spinee.2007.04.021
    Journal articles | 2007
    Chung S; Wei A; Connor DE; Webb GC; Molloy TJ; Pajic M; Diwan AD, 2007, 'Nucleus pulposus cellular longevity by telomerase gene therapy', Spine, vol. 32, pp. 1188 - 1196, http://dx.doi.org/10.1097/BRS.0b013e31805471a3
    Journal articles | 2007
    Hansen R; Williamson D; Finnegan T; Lloyd B; Grady J; Diamond T; Smith E; Stavrinos T; Thompson M; Gwinn T; Allen BJ; Smerdely P; Diwan AD; Singh N; Singh M, 2007, 'Estimation of thigh muscle cross-sectional area by dual-energy X-ray absorptiometry in frail elderly patients', American Journal of Clinical Nutrition, vol. 86, pp. 952 - 958
    Journal articles | 2005
    Baldik Y; Diwan AD; Appleyard RC; Ming Fang Z; Wang Y; Murrell GA, 2005, 'Deletion of iNOS gene impairs mouse fracture healing', Bone, vol. 37, pp. 32 - 36, http://dx.doi.org/10.1016/j.bone.2004.10.002
    Journal articles | 2005
    Khan SN; Cammisa FP; Sandha H; Diwan AD; Girardi F; Lane JM, 2005, 'The biology of bone grafting', Journal of the American Academy of Orthopaedic Surgeons, vol. 13, pp. 77 - 86, http://dx.doi.org/10.5435/00124635-200501000-00010
    Journal articles | 2005
    Lee P; Zhu CC; Sadick NS; Diwan AH; Zhang PS; Liu JS; Prieto VG, 2005, 'Expression of androgen receptor coactivator ARA70/ELE1 in androgenic alopecia', Journal of Cutaneous Pathology, vol. 32, pp. 567 - 571, http://dx.doi.org/10.1111/j.0303-6987.2005.00397.x
    Journal articles | 2004
    Diwan AD; Khan SN, 2004, 'Chronic low back pain: issues and management, part II', Orthopedic Clinics of North America, vol. 35, pp. IX - IX, http://dx.doi.org/10.1016/S0030-5898(03)00107-X
    Journal articles | 2004
    Rajaratnam R; Yee G; Low AK; Yu Y; Jansen J; Diwan A; Walsh WR, 2004, 'The effects of long term ovariectomy on fracture healing in a rat osteopenia model', Transactions - 7th World Biomaterials Congress, pp. 699
    Journal articles | 2003
    Chung SA; Khan SN; Diwan AD, 2003, 'The molecular basis of intervertebral disk degeneration', Orthopedic Clinics of North America, vol. 34, pp. 209 - 219, http://dx.doi.org/10.1016/S0030-5898(03)00026-9
    Journal articles | 2003
    Summersell PC; Turnbull A; Long G; Diwan AD; Macdessi S; Cooke PJ; Li GS, 2003, 'Temperature trends in total hip arthroplasty', Journal of Arthroplasty, vol. 18, pp. 426 - 429, http://dx.doi.org/10.1016/S0883-5403(03)00015-9
    Journal articles | 2002
    Fraser JF; Diwan AD; Peterson M; O Brien MF; Mintz DN; Khan SN; Sandhu H, 2002, 'Preoperative Magnetic Resonance Imaging Screening for a Surgical Decision Regarding the Approach for Anterior Spine Fusion at the Cervicothoracic Junction', Spine, vol. 27, pp. 675 - 681, http://dx.doi.org/10.1097/00007632-200204010-00002
    Journal articles | 2002
    Sandhu H; Toth JM; Diwan AD; Seim HB; Kanim LE; Kabo JM; Turner AS, 2002, 'Histologic Evaluation of the Efficacy of rhBMP-2 Compared with Autograft Bone in Sheep Spinal Anterior Interbody Fusion', Spine, vol. 27, pp. 567 - 575, http://dx.doi.org/10.1097/00007632-200203150-00003
    Journal articles | 2001
    Lin JH; Wang M; Wei A; Zhu W; Diwan AD; Murrell GA, 2001, 'Temporal expression of nitric oxide synthase isoforms in healing Achilles tendon', Journal of Orthopaedic Research, vol. 19, pp. 136 - 142, http://dx.doi.org/10.1016/S0736-0266(00)00019-X
    Journal articles | 2001
    Namkung-Matthai H; Appleyard RC; Jansen J; Lin JH; Masstricht S; Swain MV; Mason RS; Murrell GA; Diwan AD; Diamond T, 2001, 'Osteoporosis influences the early period of fracture healing in a rat osteoporotic modle', Bone, vol. 28, pp. 80 - 86, http://dx.doi.org/10.1016/S8756-3282(00)00414-2
    Journal articles | 2001
    Zhu W; Diwan AD; Lin JH; Murrell GA, 2001, 'Nitric oxide synthase isoforms during fracture healing', Journal of Bone and Mineral Research, vol. 16, pp. 535 - 540, http://dx.doi.org/10.1359/jbmr.2001.16.3.535
    Journal articles | 2000
    Diwan AD; Parvataneni HK; Sandhu H; Girardi F; Cammisa FP, 2000, 'Current concepts in intervertebral disc restoration', Orth, vol. 31, pp. 453 - 464, http://dx.doi.org/10.1016/S0030-5898(05)70163-2
    Journal articles | 2000
    Diwan AD; Wang M; Jang D; Zhu W; Murrell GA, 2000, 'Nitric oxide modulates fracture healing', Journal of Bone and Mineral Research, vol. 15, pp. 342 - 351
    Journal articles | 2000
    Namkung-Matthai H; Diwan AD; Mason RS; Murrell GA; Diamond T, 2000, 'Nitric oxide regulates alkaline phosphatase activity in rat fracture callus explant cultures', Redox Report, vol. 5, pp. 126 - 128, http://dx.doi.org/10.1179/135100000101535438
  • Preprints | 2020
    Chepurin D; Chamoli U; Diwan AD, 2020, Bony Stress and Its Association With Intervertebral Disc Degeneration in the Lumbar Spine: a Review of Clinical and Basic Science Studies, http://dx.doi.org/10.21203/rs.3.rs-51303/v1
    Conference Abstracts | 2020
    Diwan A; Chen X; Chamoli U; fogel H, 2020, 'Clinicians’ perceptions around discectomy surgery for lumbar disc herniation: a survey of orthopaedic and neuro-surgeons in Australia and New Zealand', in Clinicians’ perceptions around discectomy surgery for lumbar disc herniation: a survey of orthopaedic and neuro-surgeons in Australia and New Zealand, virtual, presented at Proceeding of the 2020 Spine Society of Australia Virtual Meetin, virtual, 20 November 2020 - 20 November 2020
    Conference Papers | 2019
    Zhang T; Bai S; Dokos S; Cheung JPY; Diwan AD, 2019, 'XLIF interbody cage reduces stress and strain of fixation in spinal reconstructive surgery in comparison with TLIF cage with bilateral or unilateral fixation: A computational analysis', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 1887 - 1890, http://dx.doi.org/10.1109/EMBC.2019.8856592
    Conference Papers | 2007
    Pelletier MH; Smitham PJ; Michaels D; Carter A; Diwan AD; Walsh WR, 2007, 'In vivo evaluation of a novel protein polymer hydrogel for nucleus pulpus replacement.', in Transactions of the Annual Meeting - Orthopaedic Research Society, Orthopaedic Research Society, USA, presented at 53rd Annual Meeting of the Orthoapedic Research Society, San Diego, Californa, USA