Conjoint Lecturer

Dr Brendan Julian Smyth

medicine-health
St. George Clin Sch- Operating

Dr Smyth is a staff specialist nephrologist and clinical researcher at St George Hospital. After completing his training in nephrology at Royal Prince Alfred Hospital, he has been completing a PhD in randomised controlled trials and trial methodology in hemodilaysis. He is due to submit at the end of 2019. He has developed a broad range of research skills and interests. This includes lead roles in the ACTIVE Dialysis and RESOLVE studies and in meta-analysis. He is also involved in the international promotion of clinical trials. As a member of the International Society of Nephrology's Advancing Clinical Trials working group he publishes monthly summaries of clinical trials in nephrology and is developing an online trials toolkit aimed at boosting research participation globally. He is keen to facilitate research participation locally also and to improve the understanding of research methodogies in local medical graduates.

Location
St George Hospital, Kogarah

Publications

  • Book Chapters | 2021
    Dr Brendan Julian Smyth
    Smyth B; Haber A; Hennessy A, 2021, 'Kidney Disease and Electrolyte Disorders in the Context of Drug Use', in Textbook of Addiction Treatment, Springer International Publishing, pp. 1113 - 1132, http://dx.doi.org/10.1007/978-3-030-36391-8_78
  • Journal articles | 2021
    Dr Brendan Julian Smyth
    Ng JKC; Smyth B; Marshall MR; Kang A; Pinter J; Bassi A; Krishnasamy R; Rossignol P; Rocco MV; Li Z; Jha V; Hawley CM; Kerr PG; DI Tanna GL; Woodward M; Jardine AM, 2021, 'Relationship between measured and prescribed dialysate sodium in haemodialysis: a systematic review and meta-analysis', Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, vol. 36, pp. 695 - 703, http://dx.doi.org/10.1093/ndt/gfaa287
    Journal articles | 2021
    Dr Brendan Julian Smyth
    Nataatmadja M; Krishnasamy R; Zuo L; Hong D; Smyth B; Jun M; de Zoysa JR; Howard K; Wang J; Lu C; Liu Z; Chan CT; Cass A; Perkovic V; Jardine M; Gray NA, 2021, 'Quality of Life in Caregivers of Patients Randomized to Standard- Versus Extended-Hours Hemodialysis', Kidney International Reports, vol. 6, pp. 1058 - 1065, http://dx.doi.org/10.1016/j.ekir.2021.01.020
    Journal articles | 2021
    Dr Brendan Julian Smyth
    Kang A; Arnold R; Gallagher M; Snelling P; Green J; Fernando M; Kiernan M; Hand S; Grimley K; Burman J; Heath A; Rogers K; Bhattacharya A; Smyth B; Bradbury T; Hawley C; Perkovic V; Krishnan A; Jardine M, 2021, 'Effect of Hemodiafiltration on the Progression of Neuropathy with Kidney Failure.', Clin J Am Soc Nephrol, http://dx.doi.org/10.2215/CJN.17151120
    Journal articles | 2021
    Dr Brendan Julian Smyth
    Evans RDR; Smyth B; Levin A; Jha V; Wheeler DC; Jardine M; Perkovic V; Damster S; Malik C; de Zeeuw D; Hiemstra T, 2021, 'The International Society of Nephrology Advancing Clinical Trials (ISN-ACT) Network: current activities and future goals', Kidney International, vol. 99, pp. 551 - 554, http://dx.doi.org/10.1016/j.kint.2020.10.048
    Journal articles | 2021
    Dr Brendan Julian Smyth
    Sharma S; Smyth B, 2021, 'From Proteinuria to Fibrosis: An Update on Pathophysiology and Treatment Options', Kidney and Blood Pressure Research, pp. 1 - 10, http://dx.doi.org/10.1159/000516911
    Journal articles | 2021
    Dr Brendan Julian Smyth
    YI TW; SMYTH B; KANG AMY; CARDOZA K; TANNA GLD; ARNOTT C; POLLOCK CA; AGARWAL R; BAKRIS G; CANNON CP; DE ZEEUW D; HEERSPINK HL; LEVIN A; NEAL B; WHEELER DC; ZHANG H; ZINMAN B; MAHAFFEY KW; PERKOVIC V; JARDINE MJ, 2021, '129-LB: Kidney and Cardiovascular Effects of Canagliflozin According to Age and Sex in the CREDENCE Trial', Diabetes, vol. 70, pp. 129 - LB, http://dx.doi.org/10.2337/db21-129-lb
    Journal articles | 2021
    Dr Brendan Julian Smyth
    LIAO J; KANG AMY; XIA C; ARNOTT C; TANNA GLD; KRISHNAN AV; POLLOCK CA; AGARWAL R; BAKRIS G; HEERSPINK HL; LEVIN A; DE ZEEUW D; NEAL B; ZHANG H; WHEELER DC; ZINMAN B; MAHAFFEY KW; PERKOVIC V; JARDINE MJ; SMYTH B, 2021, '131-LB: The Impact of Canagliflozin on the Risk of Neuropathy Events: Results from the CREDENCE Trial', Diabetes, vol. 70, pp. 131 - LB, http://dx.doi.org/10.2337/db21-131-lb
    Journal articles | 2021
    Dr Brendan Julian Smyth
    CARDOZA K; KANG AMY; SMYTH B; YI TW; TANNA GLD; POLLOCK CA; DE ZEEUW D; WHEELER DC; CANNON CP; ZINMAN B; JARDINE MJ; ARNOTT C; LEVIN A; MAHAFFEY KW, 2021, '133-LB: Canagliflozin Improves Cardiovascular and Renal Outcomes across Broad Geographic Regions: Results from CREDENCE', Diabetes, vol. 70, pp. 133 - LB, http://dx.doi.org/10.2337/db21-133-lb
    Journal articles | 2020
    Dr Brendan Julian Smyth
    Kang A; Smyth B; Neuen B; Lambers Heerspink H; Di Tanna GL; Neal B; Zhang H; Hockham C; Agarwal R; Bakris G; Charytan DM; De Zeeuw D; Greene T; Levin A; Pollock C; Wheeler D; Zinman B; Mahaffey KW; Perkovic V; Jardine M, 2020, 'P1019CANAGLIFLOZIN AND RISK OF SKIN AND SOFT TISSUE INFECTIONS IN PEOPLE WITH DIABETES MELLITUS AND KIDNEY DISEASE - A POST-HOC ANALYSIS OF THE CREDENCE TRIAL', Nephrology Dialysis Transplantation, vol. 35, http://dx.doi.org/10.1093/ndt/gfaa142.p1019
    Journal articles | 2020
    Dr Brendan Julian Smyth
    Smyth B; Zuo L; Gray NA; Chan CT; de Zoysa JR; Hong D; Rogers K; Wang J; Cass A; Gallagher M; Perkovic V; Jardine M, 2020, 'No evidence of a legacy effect on survival following randomization to extended hours dialysis in the ACTIVE Dialysis trial', Nephrology, vol. 25, pp. 792 - 800, http://dx.doi.org/10.1111/nep.13737
    Journal articles | 2020
    Dr Brendan Julian Smyth
    Chung EY; Risi D; Holt JL; Lonergan M; Kotwal S; Yong K; Smyth B; Chen JH; Wen C, 2020, 'A retrospective study on the epidemiology of ANCA-associated vasculitis in two Australian health districts.', Intern Med J, http://dx.doi.org/10.1111/imj.15098
    Journal articles | 2020
    Dr Brendan Julian Smyth
    Luyckx VA; Smyth B; Harris DCH; Pecoits-Filho R, 2020, 'Dialysis funding, eligibility, procurement, and protocols in low- and middle-income settings: results from the International Society of Nephrology collection survey', Kidney International Supplements, vol. 10, pp. e10 - e18, http://dx.doi.org/10.1016/j.kisu.2019.11.005
    Journal articles | 2020
    Dr Brendan Julian Smyth
    Shaman AM; Smyth B; Arnott C; Palmer SC; Mihailidou AS; Jardine MJ; Gallagher MP; Perkovic V; Jun M, 2020, 'Comparative efficacy and safety of bp-lowering pharmacotherapy in patients undergoing maintenance dialysis: A network meta-analysis of randomized, controlled trials', Clinical Journal of the American Society of Nephrology, vol. 15, pp. 1129 - 1138, http://dx.doi.org/10.2215/CJN.12201019
    Journal articles | 2020
    Dr Brendan Julian Smyth
    Smyth B; Chan CT; Grieve SM; Puranik R; Zuo L; Hong D; Gray NA; De Zoysa JR; Scaria A; Gallagher M; Perkovic V; Jardine M, 2020, 'Predictors of Change in Left-Ventricular Structure and Function in a Trial of Extended Hours Hemodialysis', Journal of Cardiac Failure, vol. 26, pp. 482 - 491, http://dx.doi.org/10.1016/j.cardfail.2020.03.010
    Journal articles | 2020
    Dr Brendan Julian Smyth
    Smyth B; Chan CT; Grieve SM; Puranik R; Zuo L; Hong D; Gray NA; de Zoysa JR; Scaria A; Gallagher M; Perkovic V; Jardine M, 2020, 'Response to: Loutradis et al. Longer Dialysis Sessions Improve Cardiac Systolic Function by Reducing Myocardial Stunning', Journal of Cardiac Failure, vol. 26, pp. 1028 - 1029, http://dx.doi.org/10.1016/j.cardfail.2020.09.001
    Journal articles | 2020
    Dr Brendan Julian Smyth
    TALBOT B; Sood A; Smyth B; Leishman G; Garvey V; Kaur N; Knight J, 2020, 'SAT-273 EARLY DETECTION OF PERITONITIS - A NOVEL APPROACH TO PERITONEAL EFFLUENT TURBIDITY', Kidney International Reports, vol. 5, pp. S116 - S117, http://dx.doi.org/10.1016/j.ekir.2020.02.290
    Journal articles | 2019
    Dr Brendan Julian Smyth
    Liu Y; Hong D; Wang AY; Guo R; Smyth B; Liu J; Sun G; Chen S; Tan N; Jardine M; Brieger D; Shaman A; Islam S; Chen J; Gallagher M, 2019, 'Effects of intravenous hydration on risk of contrast induced nephropathy and in-hospital mortality in STEMI patients undergoing primary percutaneous coronary intervention: A systematic review and meta-analysis of randomized controlled trials', BMC Cardiovascular Disorders, vol. 19, http://dx.doi.org/10.1186/s12872-019-1054-y
    Journal articles | 2019
    Dr Brendan Julian Smyth
    Smyth B; Haber A; Trongtrakul K; Hawley C; Perkovic V; Woodward M; Jardine M, 2019, 'Representativeness of Randomized Clinical Trial Cohorts in End-stage Kidney Disease: A Meta-analysis', JAMA Internal Medicine, vol. 179, pp. 1316 - 1324, http://dx.doi.org/10.1001/jamainternmed.2019.1501
    Journal articles | 2019
    Dr Brendan Julian Smyth
    Smyth B; van den Broek-Best O; Hong D; Howard K; Rogers K; Zuo L; Gray NA; de Zoysa JR; Chan CT; Lin H; Zhang L; Xu J; Cass A; Gallagher M; Perkovic V; Jardine M, 2019, 'Varying association of extended hours dialysis with quality of life', Clinical Journal of the American Society of Nephrology, vol. 14, pp. 1751 - 1762, http://dx.doi.org/10.2215/CJN.06800619
    Journal articles | 2019
    Dr Brendan Julian Smyth
    Smyth B; Krishnan AV; Gallagher M; Kiernan M; Snelling P; Hawley C; Fernando M; Hand S; Grimley K; Burman J; Heath A; Kang A; Perkovic V; Jardine MJ, 2019, 'Randomised controlled trial of the impact of haemodiafiltration on uraemic neuropathy: FINESSE study protocol', BMJ Open, vol. 9, http://dx.doi.org/10.1136/bmjopen-2018-023736
    Journal articles | 2019
    Dr Brendan Julian Smyth
    Smyth B; Kotwal S; Gallagher M; Gray NA; Polkinghorne K, 2019, 'Dialysis catheter management practices in Australia and New Zealand', Nephrology, vol. 24, pp. 827 - 834, http://dx.doi.org/10.1111/nep.13507
    Journal articles | 2019
    Dr Brendan Julian Smyth
    Liao JL; van den Broek-Best O; Smyth B; Hong D; Vo K; Zuo L; Gray NA; Chan CT; de Zoysa J; Perkovic V; Jiang L; Jardine M, 2019, 'Effect of extended hours dialysis on sleep quality in a randomized trial', Nephrology, vol. 24, pp. 430 - 437, http://dx.doi.org/10.1111/nep.13236
    Journal articles | 2019
    Dr Brendan Julian Smyth
    Smyth B, 2019, 'Studies Making Use of the Same Randomized Clinical Trial Cohorts - Reply', JAMA Internal Medicine, vol. 179, pp. 1447, http://dx.doi.org/10.1001/jamainternmed.2019.4624
    Journal articles | 2019
    Dr Brendan Julian Smyth
    Chen SQ; Liu Y; Smyth B; Li HL; Sun GL; Chen ZJ; Zhou YL, 2019, 'Clinical Implications of Contrast-Induced Nephropathy in Patients Without Baseline Renal Dysfunction Undergoing Coronary Angiography', Heart Lung and Circulation, vol. 28, pp. 866 - 873, http://dx.doi.org/10.1016/j.hlc.2018.04.291
    Journal articles | 2019
    Dr Brendan Julian Smyth
    Smyth B; Trongtrakul K; Haber A; Talbot B; Hawley C; Perkovic V; Woodward M; Jardine M, 2019, 'Inequities in the global representation of sites participating in large, multicentre dialysis trials: A systematic review', BMJ Global Health, vol. 4, http://dx.doi.org/10.1136/bmjgh-2019-001940
    Journal articles | 2019
    Dr Brendan Julian Smyth
    Zhan Z; Smyth B; Toussaint ND; Gray NA; Zuo L; De Zoysa JR; Chan CT; Jin C; Scaria A; Hawley CM; Perkovic V; Jardine MJ; Zhang L, 2019, 'Effect of extended hours dialysis on markers of chronic kidney disease-mineral and bone disorder in the ACTIVE Dialysis study', BMC Nephrology, vol. 20, http://dx.doi.org/10.1186/s12882-019-1438-3
    Journal articles | 2019
    Dr Brendan Julian Smyth
    Smyth B; Kotwal S; Gallagher M; Gray NA; Polkinghorne KR, 2019, 'Arteriovenous access practices in Australian and New Zealand dialysis units', Journal of Vascular Access, vol. 20, pp. 740 - 745, http://dx.doi.org/10.1177/1129729819851061
    Journal articles | 2019
    Dr Brendan Julian Smyth
    Gray NA; Zuo L; Hong D; Smyth B; Jun M; De Zoysa J; Vo K; Howard K; Wang J; Lu C; Liu Z; Cass A; Perkovic V; Jardine M, 2019, 'Quality of life in caregivers compared with dialysis recipients: The Co-ACTIVE sub-study of the ACTIVE dialysis trial', Nephrology, vol. 24, pp. 1056 - 1063, http://dx.doi.org/10.1111/nep.13530
    Journal articles | 2019
    Dr Brendan Julian Smyth
    Smyth B; Haber A; Trongtrakul K; Hawley C; Perkovic V; Woodward M; Jardine M, 2019, 'SAT-041 A META-ANALYSIS OF THE REPRESENTATIVENESS OF RANDOMIZED CONTROLLED TRIAL COHORTS IN END-STAGE KIDNEY DISEASE', Kidney International Reports, vol. 4, pp. S21 - S21, http://dx.doi.org/10.1016/j.ekir.2019.05.064
    Journal articles | 2018
    Dr Brendan Julian Smyth
    Smyth B; Perkovic V, 2018, 'New hypoglycemic agents and the kidney: What do the major trials tell us? [version 1; referees: 2 approved]', F1000Research, vol. 7, http://dx.doi.org/10.12688/f1000research.16135.1
    Journal articles | 2018
    Dr Brendan Julian Smyth
    Smyth B; Kotwal S; Gallagher M; Jardine M, 2018, 'FP513CARDIOVASCULAR EVENTS IN A LINKED DATA COHORT OF DIALYSIS PATIENTS: IMPACT OF MODALITY AND EVENT DEFINITION', Nephrology Dialysis Transplantation, vol. 33, pp. i211 - i211, http://dx.doi.org/10.1093/ndt/gfy104.fp513
    Journal articles | 2017
    Dr Brendan Julian Smyth
    Wang K; Li HL; Chen LL; Bei WJ; Lin KY; Smyth B; Chen SQ; Guo XS; Guo W; Liu YH; Chen PY; Chen JY; Chen KH; Liu Y; Tan N, 2017, 'Association of N-terminal pro-brain natriuretic peptide with contrast-induced acute kidney injury and long-term mortality in patients with heart failure and mid-range ejection fraction', Medicine (United States), vol. 96, http://dx.doi.org/10.1097/MD.0000000000006259
    Journal articles | 2016
    Dr Brendan Julian Smyth
    Smyth B; Ong S, 2016, 'Severe hypocalcaemia and hypophosphataemia following intravenous iron and denosumab: A novel drug interaction', Internal Medicine Journal, vol. 46, pp. 360 - 363, http://dx.doi.org/10.1111/imj.13001
    Journal articles | 2016
    Dr Brendan Julian Smyth
    Smyth B; Jones C; Saunders J, 2016, 'Prescribing for patients on dialysis', Australian Prescriber, vol. 39, pp. 21 - 24, http://dx.doi.org/10.18773/austprescr.2016.008
    Journal articles | 2016
    Dr Brendan Julian Smyth
    Smyth B; Knight JF; Herrington WG, 2016, 'The rise and rise of randomized clinical evidence in Sub-Saharan Africa', Clinical Kidney Journal, vol. 9, pp. 814 - 816, http://dx.doi.org/10.1093/ckj/sfw084
  • Conference Abstracts | 2020
    Dr Brendan Julian Smyth
    TALBOT B; Sukkar L; Smyth B; Jun M; Jardine M; Cass A; Walker R; Reith C; Hooi L; Gallagher M, 2020, 'SUN-119 COMPARING SURVIVAL IN PATIENTS WITH CHRONIC KIDNEY DISEASE ACROSS THREE COUNTRIES - RESULTS FROM THE STUDY OF HEART AND RENAL PROTECTION-EXTENDED REVIEW (SHARP-ER)', in Kidney International Reports, Elsevier BV, Vol. 5, pp. S250 - S250, http://dx.doi.org/10.1016/j.ekir.2020.02.646

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