Dr Bruno Gaeta
Senior Lecturer

Dr Bruno Gaeta

BSc (Hons) (Biochemistry) and University Medal, UNSW (1986)

PhD (Molecular Genetics), UNSW (1992)

Computer Science and Engineering

I am a Senior Lecturer in Bioinformatics and Director of Studies (Bioinformatics Engineering) with the School of Computer Science and Engineering.

Research Interest

My main research interest is in the engineering of computer methods and software to better understand the immune system and especially the basis for the "memory" of the immune system and vaccines.

This includes software for analysing immunoglobulins, both at the genetic level and at the protein level.

I am especially interested in the design of algorithms for analysing large datasets of rearranged immunoglobulin genes for the purpose of understanding genetic variation in these genes, diversity generation events, and binding specificity.

I am also more widely interested in applications of computational methods to molecular biology, especially to gene expression, and, in collaboration with Professor Sri Parameswaran, the development of specialised hardware for bioinformatics analysis.

Professional Organisations and Consulting Positions

I am very active in the promotion and advocacy for the disciplines of computational biology and bioinformatics, through involvement in the leading professional societies and conferences in the field:

  • International Society for Computational Biology (ISCB): Director and Co-chair of the Affiliates Committee 
  • Intelligent Systems in Molecular Biology (ISMB) conference (2017-present): Steering Committee Member

Past Appointments and Contributions

  • 2017-2021: Treasurer and Executive Committee Member, International Society for Computational Biology (ISCB)
  • 2008-2019: Executive Committee Member, Asia-Pacific Bioinformatics Network (APBioNet)
  • 2016-2019: Operational Board Member, Global Organisation for Bioinformatics Learning, Education and Training (GOBLET)
  • 2006: Conference chair, Bioinformatics Australia conference (Sydney)
  • 2005-2010: Management committee, Bioinformatics Australia
  • 2002: Advisory Board, Thailand National Bioinformatics Helpdesk
  • 2001-2002: Adjunct Lecturer, School of Molecular and Microbial Biosciences, University of Sydney 
  • 1999-2001: Adjunct Lecturer, School of Microbiology, University of Sydney 
  • 1999-2001: Director of Education and Senior Scientist, eBioinformatics Pty Ltd (re-named Entigen Inc)
  • 2000: Adviser/consultant for the Biotechnology program of the Thailand-Australia Science and Engineering Assistance Project 
  • 1993-1998: Liaison Officer and Education Officer, Australian Genomic Information Centre, University of Sydney.
  • 1991-1993: Post-Doctoral Research Officer, Heart Research Institute, Camperdown, NSW

Program Committee member for conferences and workshops including Pattern Recognition in Bioinformatics, International Conference on Bioinformatics (InCoB), GIW, Computational Models for Life Sciences, and International Conference on Intelligent Sensing and Information Processing, International Conference on Artificial Immune Systems

Manuscript reviewer for PLoS Computational Biology, Bioinformatics, Briefings in Bioinformatics, BMC Bioinformatics, Journal of Theoretical Biology and Comparative and Functional Genomics

+61 2 9385 7213
401C, K17
  • Journal articles | 2019
    Wang H; Chu W; Ye C; Gaeta B; Tao H; Wang M; Qiu Z, 2019, 'Chlorogenic acid attenuates virulence factors and pathogenicity of Pseudomonas aeruginosa by regulating quorum sensing', Applied Microbiology and Biotechnology, vol. 103, pp. 903 - 915, http://dx.doi.org/10.1007/s00253-018-9482-7
    Journal articles | 2015
    Atwood TK; Bongcam-Rudloff E; Brazas ME; Corpas M; Gaudet P; Lewitter F; Mulder N; Palagi PM; Schneider MV; van Gelder CWG; Attwood TK; Banag C; Blackford S; Blatter MC; Brazas MD; Brooksbank C; Budd A; Charleston M; Christoffels A; Conesa A; Crowe M; Davies A; de Crecy-Lagard V; De Las Rivas J; Doyle M; Edwards R; Facchiano A; Fernandes P; Gaeta B; Heger A; Herringa J; Hughes D; Jimenez RC; Kille P; Korpelainen E; Kumuthini J; MacLean D; Martinez SAR; McGrath A; Michalopoulos I; Mulder N; Ouellette BF; Palagi PM; Pearson WR; Qi W; Romano P; Rother K; Sansone SA; Schönbach C; Tastan-Bishop O; Trelles O; Twells R; Via A; Vriend G; Warnow T; Watson M; Westervelt N; Zanzoni A, 2015, 'GOBLET: The Global Organisation for Bioinformatics Learning, Education and Training', PLoS Computational Biology, vol. 11, http://dx.doi.org/10.1371/journal.pcbi.1004143
    Journal articles | 2015
    Corpas M; Jimenez RC; Bongcam-Rudloff E; Budd A; Brazas MD; Fernandes PL; Gaeta B; Van Gelder C; Korpelainen E; Lewitter F; McGrath A; MacLean D; Palagi PM; Rother K; Taylor J; Via A; Watson M; Schneider MV; Attwood TK, 2015, 'The GOBLET training portal: A global repository of bioinformatics training materials, courses and trainers', Bioinformatics, vol. 31, pp. 140 - 142, http://dx.doi.org/10.1093/bioinformatics/btu601
    Journal articles | 2014
    Welch L; Lewitter F; Schwartz R; Brooksbank C; Radivojac P; Gaeta B; Schneider MV, 2014, 'Bioinformatics Curriculum Guidelines: Toward a Definition of Core Competencies', PLoS Computational Biology, vol. 10, http://dx.doi.org/10.1371/journal.pcbi.1003496
    Journal articles | 2013
    Ballouz S; Liu JY; George RA; Bains N; Liu A; Oti M; Gaeta B; Fatkin D; Wouters MA, 2013, 'Gentrepid V2.0: A web server for candidate disease gene prediction', BMC Bioinformatics, vol. 14, http://dx.doi.org/10.1186/1471-2105-14-249

My Research Supervision

I am currently supervising one PhD student in my group, and up to four Honours students per year.

I have previously graduated 4 PhD students and 2 MSc students.

My Teaching

I am Director of Studies for the Bioinformatics Engineering program, and for the Bioinformatics major at UNSW.

Lectures/Courses taught

  • BINF2010 Introduction to Bioinformatics
  • BINF3010/9010 Applied Bioinformatics
  • BINF3020/9020 Computational Bioinformatics
  • DESN2000 Engineering Design and Professional Practice