Dr Chantal Kopecky

Postdoctoral Fellow

2018: Promotion to Lecturer, UNSW Sydney

2015: PhD in Immunology, Medical University of Vienna, Austria

2009: MSc in Nutrition Science, University of Vienna, Austria

Science

School of Chemistry

I obtained my PhD in Immunology at the Medical University of Vienna, Austria in the field of cardiovascular and lipoprotein biology in chronic kidney disease. Extending my work in Austria as junior Post-doctoral Fellow my research was further focused on linking molecular changes in lipid quality with clinical outcomes in cardiovascular high-risk patient populations.

After moving to Sydney in 2016, I was investigating metabolic and inflammatory complications in diabetes and cardiovascular disease at UNSW. Specifically, I utilised 3D lightsheet fluorescence imaging to visualise pathologic processes, immune cell involvement and disease progression in atherosclerosis and I was working on characterising impairments of skeletal muscle metabolism in the context of diabetes.

Working in the Pancreatic Cancer Translational Research Group at UNSW from 2018 - 2020, my research was focused on efficacy of drug delivery and novel therapeutic approaches in pancreatic cancer. Specific projects were aimed to investigate therapeutic targets to metabolically reprogramm the stroma in pancreatic cancer and the development of novel nanomedicines to deliver gene therapeutics to pancreatic tumours.

Currently, I am working in the field of Biomaterials and Tissue Engineering (Kilian Lab UNSW) with a specific focus on cancer mechanobiology and the development of novel 3D tumour micorenvironments.

Location

Hilmer Building Level 7 Sydney NSW 2052

Journal articles | 2024

Johnson KK; Koshy P; Kopecky C; Devadason M; Biazik J; Zheng X; Jiang Y; Wang X; Liu Y; Holst J; Yang JL; Kilian KA; Sorrell CC, 2024, 'ROS-mediated anticancer effects of EGFR-targeted nanoceria', Journal of Biomedical Materials Research - Part A, 112, pp. 754 - 769, http://dx.doi.org/10.1002/jbm.a.37656

Journal articles | 2024

Kopecky C; Haug M; Reischl B; Deshpande N; Manandhar B; King TW; Lee V; Wilkins MR; Morris M; Polly P; Friedrich O; Rye KA; Cochran BJ, 2024, 'Effect of insulin insufficiency on ultrastructure and function in skeletal muscle', Journal of Cachexia, Sarcopenia and Muscle, 15, pp. 112 - 123, http://dx.doi.org/10.1002/jcsm.13380

Journal articles | 2023

K. Johnson K; Kopecky C; Koshy P; Liu Y; Devadason M; Holst J; A. Kilian K; C. Sorrell C, 2023, 'Theranostic Activity of Ceria-Based Nanoparticles toward Parental and Metastatic Melanoma: 2D vs 3D Models', ACS Biomaterials Science and Engineering, 9, pp. 1053 - 1065, http://dx.doi.org/10.1021/acsbiomaterials.2c01258

Journal articles | 2023

Liu Y; Nemec S; Kopecky C; Stenzel MH; Kilian KA, 2023, 'Hydrogel Microtumor Arrays to Evaluate Nanotherapeutics', Advanced Healthcare Materials, 12, http://dx.doi.org/10.1002/adhm.202201696

Journal articles | 2023

Molley TG; Jiang S; Ong L; Kopecky C; Ranaweera CD; Jalandhra GK; Milton L; Kardia E; Zhou Z; Rnjak-Kovacina J; Waters SA; Toh YC; Kilian KA, 2023, 'Gas-modulating microcapsules for spatiotemporal control of hypoxia', Proceedings of the National Academy of Sciences of the United States of America, 120, pp. e2217557120, http://dx.doi.org/10.1073/pnas.2217557120

Journal articles | 2023

Srivastava P; Romanazzo S; Kopecky C; Nemec S; Ireland J; Molley TG; Lin K; Jayathilaka PB; Pandzic E; Yeola A; Chandrakanthan V; Pimanda J; Kilian K, 2023, 'Defined Microenvironments Trigger In Vitro Gastrulation in Human Pluripotent Stem Cells', Advanced Science, 10, http://dx.doi.org/10.1002/advs.202203614

Journal articles | 2022

Antlanger M; Domenig O; Kaltenecker CC; Kovarik JJ; Rathkolb V; Müller MM; Schwaiger E; Hecking M; Poglitsch M; Säemann MD; Kopecky C, 2022, 'Combined sodium glucose co-transporter-2 inhibitor and angiotensin-converting enzyme inhibition upregulates the renin-angiotensin system in chronic kidney disease with type 2 diabetes: Results of a randomized, double-blind, placebo-controlled exploratory trial', Diabetes, Obesity and Metabolism, 24, pp. 816 - 826, http://dx.doi.org/10.1111/dom.14639

Journal articles | 2022

Nemec S; Ganda S; Al Taief K; Kopecky C; Kuchel R; Lebhar H; Marquis CP; Thordarson P; Kilian KA, 2022, 'A Tunable Tumor Microenvironment through Recombinant Bacterial Collagen-Hyaluronic Acid Hydrogels', ACS Applied Bio Materials, 5, pp. 4581 - 4588, http://dx.doi.org/10.1021/acsabm.2c00186

Journal articles | 2022

Romanazzo S; Kopecky C; Jiang S; Doshi R; Mukund V; Srivastava P; Rnjak-Kovacina J; Kelly K; Kilian KA, 2022, 'Biomaterials directed activation of a cryostable therapeutic secretome in induced pluripotent stem cell derived mesenchymal stromal cells', Journal of Tissue Engineering and Regenerative Medicine, 16, pp. 1008 - 1018, http://dx.doi.org/10.1002/term.3347

Journal articles | 2021

Kokkinos J; Ignacio RM; Haghighi K; Kopecky C; Sharbeen G; Gonzales-Aloy E; Youkhana J; Butler L; Goldstein D; McCarroll J; Phillips P, 2021, 'Patient-derived pancreatic tumours in a dish: implications for real-time precision medicine', HPB, 23, pp. S235 - S235, http://dx.doi.org/10.1016/j.hpb.2020.11.590

Journal articles | 2021

Kovarik JJ; Kaltenecker CC; Domenig O; Antlanger M; Poglitsch M; Kopecky C; Säemann MD, 2021, 'Effect of Mineralocorticoid Receptor Antagonism and ACE Inhibition on Angiotensin Profiles in Diabetic Kidney Disease: An Exploratory Study', Diabetes Therapy, 12, pp. 2485 - 2498, http://dx.doi.org/10.1007/s13300-021-01118-7

Journal articles | 2021

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2021, 'Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to slc7a11 inhibition', Cancer Research, 81, pp. 3461 - 3479, http://dx.doi.org/10.1158/0008-5472.CAN-20-2496

Journal articles | 2021

2021, 'Ex vivo culture of intact human patient derived pancreatic tumour tissue', , http://dx.doi.org/10.1038/s41598-021-81299-0

Journal articles | 2020

Kaltenecker CC; Domenig O; Kopecky C; Antlanger M; Poglitsch M; Berlakovich G; Kain R; Stegbauer J; Rahman M; Hellinger R; Gruber C; Grobe N; Fajkovic H; Eskandary F; Böhmig GA; Säemann MD; Kovarik JJ, 2020, 'Critical Role of Neprilysin in Kidney Angiotensin Metabolism', Circulation Research, 127, pp. 593 - 606, http://dx.doi.org/10.1161/CIRCRESAHA.119.316151

Journal articles | 2020

Kokkinos J; Sharbeen G; Haghighi K; Ignacio RM; Kopecky C; Gonzales-Aloy E; Youkhana J; Pandzic E; Boyer C; Davis T; Butler L; Goldstein D; McCarroll J; Phillips P, 2020, 'Bringing the pancreas patient back to the bench: Ex vivo culture of intact human patient derived pancreatic tumour tissue', , http://dx.doi.org/10.1101/2020.07.30.223925

Journal articles | 2019

Kopecky C; Lytvyn Y; Domenig O; Antlanger M; Kovarik JJ; Kaltenecker CC; Poglitsch M; Perkins BA; Rye KA; Cherney DZI; Säemann MD, 2019, 'Molecular regulation of the renin–angiotensin system by sodium–glucose cotransporter 2 inhibition in type 1 diabetes mellitus', Diabetologia, 62, pp. 1090 - 1093, http://dx.doi.org/10.1007/s00125-019-4871-8

Journal articles | 2019

Kopecky C; Pandzic E; Parmar A; Szajer J; Lee V; Dupuy A; Arthur A; Fok S; Whan R; Ryder WJ; Rye KA; Cochran BJ, 2019, 'Translocator protein localises to CD11b ⁺ macrophages in atherosclerosis', Atherosclerosis, 284, pp. 153 - 159, http://dx.doi.org/10.1016/j.atherosclerosis.2019.03.011

Journal articles | 2019

Kovarik JJ; Kaltenecker CC; Kopecky C; Domenig O; Antlanger M; Werzowa J; Eskandary F; Kain R; Poglitsch M; Schmaldienst S; Böhmig GA; Säemann MD, 2019, 'Intrarenal Renin-Angiotensin-System Dysregulation after Kidney Transplantation', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-46114-x

Journal articles | 2019

Raupachova J; Kopecky C; Cohen G, 2019, 'High-density lipoprotein from chronic kidney disease patients modulates polymorphonuclear leukocytes', Toxins, 11, http://dx.doi.org/10.3390/toxins11020073

Journal articles | 2019

Schwaiger E; Burghart L; Signorini L; Ristl R; Kopecky C; Tura A; Pacini G; Wrba T; Antlanger M; Schmaldienst S; Werzowa J; Säemann MD; Hecking M, 2019, 'Empagliflozin in posttransplantation diabetes mellitus: A prospective, interventional pilot study on glucose metabolism, fluid volume, and patient safety.', Am J Transplant, 19, pp. 907 - 919, http://dx.doi.org/10.1111/ajt.15223

Journal articles | 2018

Reinthaler EM; Graf E; Zrzavy T; Wieland T; Hotzy C; Kopecky C; Pferschy S; Schmied C; Leutmezer F; Keilani M; Lill CM; Hoffjan S; Epplen JT; Zettl UK; Hecker M; Deutschländer A; Meuth SG; Ahram M; Mustafa B; El-Khateeb M; Vilariño-Güell C; Sadovnick AD; Zimprich F; Tomkinson B; Strom T; Kristoferitsch W; Lassmann H; Zimprich A, 2018, 'TPP2 mutation associated with sterile brain inflammation mimicking MS.', Neurol Genet, 4, pp. e285, http://dx.doi.org/10.1212/NXG.0000000000000285

Journal articles | 2018

Werzowa JM; Säemann MD; Mohl A; Bergmann M; Kaltenecker CC; Brozek W; Thomas A; Haidinger M; Antlanger M; Kovarik JJ; Kopecky C; Song PXK; Budde K; Pascual J; Hecking M, 2018, 'A randomized controlled trial-based algorithm for insulin-pump therapy in hyperglycemic patients early after kidney transplantation.', PLoS One, 13, pp. e0193569, http://dx.doi.org/10.1371/journal.pone.0193569

Journal articles | 2017

Antlanger M; Aschauer S; Kopecky C; Hecking M; Kovarik JJ; Werzowa J; Mascherbauer J; Genser B; Säemann MD; Bonderman D, 2017, 'Heart Failure with Preserved and Reduced Ejection Fraction in Hemodialysis Patients: Prevalence, Disease Prediction and Prognosis.', Kidney Blood Press Res, 42, pp. 165 - 176, http://dx.doi.org/10.1159/000473868

Journal articles | 2017

Antlanger M; Bernhofer S; Kovarik JJ; Kopecky C; Kaltenecker CC; Domenig O; Poglitsch M; Säemann MD, 2017, 'Effects of direct renin inhibition versus angiotensin II receptor blockade on angiotensin profiles in non-diabetic chronic kidney disease.', Ann Med, 49, pp. 525 - 533, http://dx.doi.org/10.1080/07853890.2017.1313447

Journal articles | 2017

Antlanger M; Domenig O; Kovarik JJ; Kaltenecker CC; Kopecky C; Poglitsch M; Säemann MD, 2017, 'Molecular remodeling of the renin-angiotensin system after kidney transplantation.', J Renin Angiotensin Aldosterone Syst, 18, pp. 1470320317705232, http://dx.doi.org/10.1177/1470320317705232

Journal articles | 2017

Kopecky C; Ebtehaj S; Genser B; Drechsler C; Krane V; Antlanger M; Kovarik JJ; Kaltenecker CC; Parvizi M; Wanner C; Weichhart T; Säemann MD; Tietge UJF, 2017, 'HDL Cholesterol Efflux Does Not Predict Cardiovascular Risk in Hemodialysis Patients.', J Am Soc Nephrol, 28, pp. 769 - 775, http://dx.doi.org/10.1681/ASN.2016030262

Journal articles | 2017

Kopecky C; Michlits G; Säemann MD; Weichhart T, 2017, 'Pro- versus Anti-inflammatory Actions of HDLs in Innate Immunity', Cell Metabolism, 26, pp. 2 - 3, http://dx.doi.org/10.1016/j.cmet.2017.04.007

Journal articles | 2017

Kovarik JJ; Kopecky C; Antlanger M; Domenig O; Kaltenecker CC; Werzowa J; Hecking M; Mahr S; Grömmer M; Wallner C; Aumayr K; Kain R; Zuckermann A; Poglitsch M; Säemann MD, 2017, 'Effects of angiotensin-converting-enzyme inhibitor therapy on the regulation of the plasma and cardiac tissue renin-angiotensin system in heart transplant patients.', J Heart Lung Transplant, 36, pp. 355 - 365, http://dx.doi.org/10.1016/j.healun.2016.08.022

Journal articles | 2017

Sponder M; Kopecky C; Campean I-A; Emich M; Fritzer-Szekeres M; Litschauer B; Graf S; Säemann MD; Strametz-Juranek J, 2017, 'Sports and HDL-Quality Reflected By Serum Amyloid A and Surfactant Protein B.', Int J Med Sci, 14, pp. 1040 - 1048, http://dx.doi.org/10.7150/ijms.20388

Journal articles | 2017

Sponder M; Kopecky C; Campean IA; Emich M; Bergler-Klein J; Graf S; Saeemann M; Strametz-Juranek J, 2017, 'P5311Influence of physical activity on hdl-quality reflected by serum amyloid a and surfactant protein b', European Heart Journal, 38, http://dx.doi.org/10.1093/eurheartj/ehx493.p5311

Journal articles | 2016

Antlanger M; Domenig O; Kovarik JJ; Kaltenecker CC; Kopecky C; Poglitsch M; Säemann MD, 2016, 'MP012MOLECULAR REMODELING OF THE RENIN ANGIOTENSIN SYSTEM FOLLOWING RENAL TRANSPLANTATION', Nephrology Dialysis Transplantation, 31, pp. i347 - i347, http://dx.doi.org/10.1093/ndt/gfw181.12

Journal articles | 2016

Ebtehaj S; Kopecky C; Genser B; Drechsler C; Krane V; Antlanger M; J. Kovarik J; C. Kaltenecker C; Parvizi M; Wanner C; Weichhart T; Säemann MD; Tietge UJ, 2016, 'Abstract 622: High-density Lipoprotein Cholesterol Efflux Does Not Predict Cardiovascular Risk in Hemodialysis Patients', Arteriosclerosis, Thrombosis, and Vascular Biology, 36, http://dx.doi.org/10.1161/atvb.36.suppl_1.622

Journal articles | 2016

Kopecky C; Ebtehaj S; Genser B; Wanner C; Saemann MD; Tietge U, 2016, 'HDL cholesterol efflux is not predictive of cardiovascular risk in diabetic patients on hemodialysis', Atherosclerosis, 252, pp. e107 - e107, http://dx.doi.org/10.1016/j.atherosclerosis.2016.07.594

Journal articles | 2016

Kopecky C; Ebtehaj S; Genser B; Wanner C; Säemann MD; Tietge U, 2016, 'SP479HDL CHOLESTEROL EFFLUX IS NOT PREDICTIVE OF CARDIOVASCULAR RISK IN DIABETIC PATIENTS ON HEMODIALYSIS', Nephrology Dialysis Transplantation, 31, pp. i253 - i253, http://dx.doi.org/10.1093/ndt/gfw172.19

Journal articles | 2016

Kopecky C; Tufaro C; Antlanger M; Säemann MD; Bonderman D, 2016, 'SP485HDL PROTEIN COMPOSITION IN PATIENTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION AND END STAGE RENAL DISEASE', Nephrology Dialysis Transplantation, 31, pp. i255 - i255, http://dx.doi.org/10.1093/ndt/gfw172.25

Journal articles | 2016

Kovarik JJ; Antlanger M; Domenig O; Kaltenecker CC; Hecking M; Haidinger M; Werzowa J; Kopecky C; Säemann MD, 2016, 'Molecular regulation of the renin-angiotensin system in haemodialysis patients.', Nephrol Dial Transplant, 31, pp. 851, http://dx.doi.org/10.1093/ndt/gfw071

Journal articles | 2016

Kovarik JJ; Kaltenecker CC; Domenig O; Kopecky C; Antlanger M; Poglitsch M; Kain R; Eskandary F; Böhmig GA; Säemann MD, 2016, 'MO020CHYMASE AND NEPRILYSIN ARE KEY REGULATORS OF THE CLASSICAL AND ALTERNATIVE RENIN ANGIOTENSIN SYSTEM (RAS) AFTER KIDNEY TRANSPLANTATION: IMPLICATIONS FOR RAS BLOCKINGTHERAPY', Nephrology Dialysis Transplantation, 31, pp. i36 - i36, http://dx.doi.org/10.1093/ndt/gfw133.02

Journal articles | 2015

Antlanger M; Aschauer S; Kopecky C; Mascherbauer J; Bonderman D; Säemann M, 2015, 'FP608HEART FAILURE WITH PRESERVED AND REDUCED EJECTION FRACTION IN HEMODIALYSIS PATIENTS: DIAGNOSIS, PREVALENCE AND ASSOCIATED FACTORS', Nephrology Dialysis Transplantation, 30, pp. iii276 - iii276, http://dx.doi.org/10.1093/ndt/gfv181.01

Journal articles | 2015

Haidinger M; Antlanger M; Kopecky C; Kovarik JJ; Säemann MD; Werzowa J, 2015, 'Post-transplantation diabetes mellitus: evaluation of treatment strategies.', Clin Transplant, 29, pp. 415 - 424, http://dx.doi.org/10.1111/ctr.12541

Journal articles | 2015

Holzer M; Schilcher G; Curcic S; Trieb M; Ljubojevic S; Stojakovic T; Scharnagl H; Kopecky CM; Rosenkranz AR; Heinemann A; Marsche G, 2015, 'Dialysis Modalities and HDL Composition and Function.', J Am Soc Nephrol, 26, pp. 2267 - 2276, http://dx.doi.org/10.1681/ASN.2014030309

Journal articles | 2015

Kaltenecker C; Domenig O; Kopecky C; Antlanger M; Poglitsch M; Kain R; Säemann MD; Kovarik JJ, 2015, 'PP.39.21', Journal of Hypertension, 33, pp. e490 - e490, http://dx.doi.org/10.1097/01.hjh.0000468933.96228.b6

Journal articles | 2015

Kaltenecker CC; Domenig O; Kopecky C; Antlanger M; Poglitsch M; Manzel A; Linker R; Kain R; Säemann MD; Kovarik JJ, 2015, 'SP056OF MICE AND MEN: COMPARATIVE ANALYSIS OF ANGIOTENSIN FORMATION IN HEALTHY HUMAN AND MURINE KIDNEYS', Nephrology Dialysis Transplantation, 30, pp. iii398 - iii399, http://dx.doi.org/10.1093/ndt/gfv188.19

Journal articles | 2015

Kane JP; Malloy MJ; Pullinger CR, 2015, 'HDL cholesterol efflux capacity and cardiovascular events.', N Engl J Med, 372, pp. 1871, http://dx.doi.org/10.1056/NEJMc1503139

Journal articles | 2015

Kopecky C; Genser B; Drechsler C; Krane V; Kaltenecker CC; Hengstschläger M; März W; Wanner C; Säemann MD; Weichhart T, 2015, 'Quantification of HDL proteins, cardiac events, and mortality in patients with type 2 diabetes on hemodialysis.', Clin J Am Soc Nephrol, 10, pp. 224 - 231, http://dx.doi.org/10.2215/CJN.06560714

Journal articles | 2015

Kopecky C; Genser B; März W; Wanner C; Säemann MD; Weichhart T, 2015, 'HDL-Proteine sind mit kardiovaskulärem Risiko und Mortalität bei Patienten mit Typ 2-Diabetes an der Hämodialyse assoziiert', Nieren- und Hochdruckkrankheiten, 44, pp. 159 - 165, http://dx.doi.org/10.5414/nhx01694

Journal articles | 2015

Kopecky C; Haidinger M; Birner-Grünberger R; Darnhofer B; Kaltenecker CC; Marsche G; Holzer M; Weichhart T; Antlanger M; Kovarik JJ; Werzowa J; Hecking M; Säemann MD, 2015, 'Restoration of renal function does not correct impairment of uremic HDL properties.', J Am Soc Nephrol, 26, pp. 565 - 575, http://dx.doi.org/10.1681/ASN.2013111219

Journal articles | 2015

Kovarik JJ; Antlanger M; Domenig O; Kaltenecker CC; Hecking M; Haidinger M; Werzowa J; Kopecky C; Säemann MD, 2015, 'Molecular regulation of the renin-angiotensin system in haemodialysis patients.', Nephrol Dial Transplant, 30, pp. 115 - 123, http://dx.doi.org/10.1093/ndt/gfu265

Journal articles | 2015

Kovarik JJ; Kaltenecker CC; Domenig O; Kopecky C; Antlanger M; Poglitsch M; Kain R; Eskandary F; Böhmig GA; Säemann MD, 2015, '8D.03', Journal of Hypertension, 33, pp. e113 - e114, http://dx.doi.org/10.1097/01.hjh.0000467657.23414.54

Journal articles | 2015

Kovarik JJ; Kaltenecker CC; Domenig O; Kopecky C; Antlanger M; Werzowa J; Hecking M; Poglitsch M; Kain R; Eskandary F; Böhmig GA; Säemann MD, 2015, 'FP842EVIDENCE FOR AN ACE-INDEPENDENT TISSUE-SPECIFIC RAS REGULATION AFTER KIDNEY TRANSPLANTATION', Nephrology Dialysis Transplantation, 30, pp. iii359 - iii359, http://dx.doi.org/10.1093/ndt/gfv185.31

Journal articles | 2015

Kovarik JJ; Kopecky C; Antlanger M; Domenig O; Kaltenecker CC; Werzowa J; Hecking M; Mahr S; Kain R; Zuckermann A; Poglitsch M; Säemann MD, 2015, 'PP.39.20', Journal of Hypertension, 33, pp. e490 - e490, http://dx.doi.org/10.1097/01.hjh.0000468932.96228.ff

Journal articles | 2015

Kovarik JJ; Kopecky C; Antlanger M; Domenig O; Kaltenecker CC; Werzowa J; Hecking M; Mahr S; Zuckermann A; Kain R; Poglitsch M; Säemann MD, 2015, 'FP274ACE-INDEPENDENT RAS ENZYME ACTIVITIES IN HEART TRANSPLANT PATIENTS WITH CHRONIC KIDNEY DISEASE (CKD)', Nephrology Dialysis Transplantation, 30, pp. iii158 - iii159, http://dx.doi.org/10.1093/ndt/gfv174.09

Journal articles | 2015

Zewinger S; Drechsler C; Kleber ME; Dressel A; Riffel J; Triem S; Lehmann M; Kopecky C; Säemann MD; Lepper PM; Silbernagel G; Scharnagl H; Ritsch A; Thorand B; de las Heras Gala T; Wagenpfeil S; Koenig W; Peters A; Laufs U; Wanner C; Fliser D; Speer T; März W, 2015, 'Serum amyloid A: high-density lipoproteins interaction and cardiovascular risk.', Eur Heart J, 36, pp. 3007 - 3016, http://dx.doi.org/10.1093/eurheartj/ehv352

Journal articles | 2015

Zewinger S; Speer T; Drechsler C; Kleber ME; Dressel A; Riffel J; Lehmann M; Kopecky C; Säemann MD; Lepper PM; Silbernagel G; Scharnagl H; Ritsch A; Laufs U; Wanner C; Fliser D; März W, 2015, 'FO005SERUM AMYLOID A (SAA) AND HIGH DENSITY LIPOPROTEINS (HDL) INTERACTION AND CARDIOVASCULAR RISK IN RENAL PATIENTS', Nephrology Dialysis Transplantation, 30, pp. iii2 - iii2, http://dx.doi.org/10.1093/ndt/gfv135.05

Journal articles | 2014

Bajari TM; Winnicki W; Gensberger E-T; Scharrer SI; Regele H; Aumayr K; Kopecky C; Gmeiner BM; Hermann M; Zeillinger R; Sengölge G, 2014, 'Known players, new interplay in atherogenesis: Chronic shear stress and carbamylated-LDL induce and modulate expression of atherogenic LR11 in human coronary artery endothelium.', Thromb Haemost, 111, pp. 323 - 332, http://dx.doi.org/10.1160/TH12-12-0924

Journal articles | 2014

Haidinger M; Werzowa J; Hecking M; Antlanger M; Stemer G; Pleiner J; Kopecky C; Kovarik JJ; Döller D; Pacini G; Säemann MD, 2014, 'Efficacy and safety of vildagliptin in new-onset diabetes after kidney transplantation--a randomized, double-blind, placebo-controlled trial.', Am J Transplant, 14, pp. 115 - 123, http://dx.doi.org/10.1111/ajt.12518

Journal articles | 2014

Kopecky C; Michael H; Birner-Gruenberger R; Christopher K; Gunther M; Saemann M, 2014, 'Molecular Composition and Function of High-Density Lipoprotein Is Uniquely Altered After Kidney Transplantation.', Transplantation, 98, pp. 565 - 565, http://dx.doi.org/10.1097/00007890-201407151-01897

Journal articles | 2013

Haidinger M; Werzowa J; Kain R; Antlanger M; Hecking M; Pfaffenberger S; Mascherbauer J; Gremmel T; Gilbertson JA; Rowczenio D; Weichhart T; Kopecky C; Hörl WH; Hawkins PN; Säemann MD, 2013, 'Hereditary amyloidosis caused by R554L fibrinogen Aα-chain mutation in a Spanish family and review of the literature.', Amyloid, 20, pp. 72 - 79, http://dx.doi.org/10.3109/13506129.2013.781998

Journal articles | 2013

Porrini E; Silva I; Ibernon M; Rocio B; Diaz JM; Delgado Mallen P; Osorio JM; Moreso F; Torres A; Haidinger M; Werzowa J; Hecking M; Stemer G; Pleiner J; Kopecky C; Pacini G; Antlanger M; Saemann MD, 2013, 'Management of diabetes in advanced CKD', Nephrology Dialysis Transplantation, 28, pp. i77 - i77, http://dx.doi.org/10.1093/ndt/gft190

Journal articles | 2012

Atamaniuk J; Kopecky C; Skoupy S; Säemann MD; Weichhart T, 2012, 'Apoptotic cell-free DNA promotes inflammation in haemodialysis patients.', Nephrol Dial Transplant, 27, pp. 902 - 905, http://dx.doi.org/10.1093/ndt/gfr695

Journal articles | 2012

Weichhart T; Kopecky C; Kubicek M; Haidinger M; Doller D; Katholnig K; Suarna C; Eller P; Tolle M; Gerner C; Zlabinger GJ; Van der giet M; Horl W; Stocker R; Saemann M, 2012, 'Serum amyloid A in uremic HDL promotes inflammation.', Journal of the American Society of Nephrology, 23, pp. 934 - 947, http://dx.doi.org/10.1681/ASN.2011070668

Journal articles | 2012

Weichhart T; Kopecky C; Kubicek M; Haidinger M; Döller D; Katholnig K; Suarna C; Eller P; Tölle M; Gerner C; Zlabinger GJ; Van Der Giet M; Hörl WH; Stocker R; Säemann MD, 2012, 'When "good" cholesterol becomes bad', Vasomed, 24, pp. 95 - 96

Journal articles | 2011

Weichhart T; Haidinger M; Katholnig K; Kopecky C; Poglitsch M; Lassnig C; Rosner M; Zlabinger GJ; Hengstschläger M; Müller M; Hörl WH; Säemann MD, 2011, 'Inhibition of mTOR blocks the anti-inflammatory effects of glucocorticoids in myeloid immune cells.', Blood, 117, pp. 4273 - 4283, http://dx.doi.org/10.1182/blood-2010-09-310888

Journal articles | 2010

Säemann MD; Poglitsch M; Kopecky C; Haidinger M; Hörl WH; Weichhart T, 2010, 'The versatility of HDL: a crucial anti-inflammatory regulator.', Eur J Clin Invest, 40, pp. 1131 - 1143, http://dx.doi.org/10.1111/j.1365-2362.2010.02361.x
Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Data from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.c.6512931

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Data from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.c.6512931.v1

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Figure S1 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428180

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Figure S1 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428180.v1

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Figure S2 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428177

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Figure S2 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428177.v1

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Figure S3 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428168

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Figure S3 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428168.v1

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Figure S4 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428165

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Figure S4 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428165.v1

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Supplementary Table 1 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428162

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Supplementary Table 1 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428162.v1

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Supplementary Table 2 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428159

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Supplementary Table 2 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428159.v1

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Supplementary Table 3 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428156

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Supplementary Table 3 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428156.v1

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Supplementary Table 4 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428153

Other | 2023

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2023, Supplementary Table 4 from Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition, , http://dx.doi.org/10.1158/0008-5472.22428153.v1

Preprints | 2022

Kokkinos J; Sharbeen G; Ignacio RM; Pandzic E; Youkhana J; Boyer C; Haghighi K; Gunawarman M; Goldstein D; Gebski V; Pajic M; Pitiyarachchi O; Davis M; Schulstad G; Arkell OSM; Kopecky C; Gonzales-Aloy E; Erkan M; Morton J; Kavallaris M; Gunning P; Hardeman E; Johns A; Gill A; Whan R; Mawson A; McCarroll J; Phillips P; Australian Pancreatic Cancer Genome Initiative , 2022, βIII-Tubulin is a Brake on Extrinsic Cell-Death in Pancreatic Cancer, , http://dx.doi.org/10.1101/2022.09.29.510034

Preprints | 2022

Kopecky C; Haug M; Reischl B; Deshpande N; Manandhar B; King T; Lee V; Wilkins M; Morris M; Polly P; Friedrich O; Rye K-A; Cochran B, 2022, Effect of insulin insufficiency on ultrastructure and function in skeletal muscle, , http://dx.doi.org/10.1101/2022.12.18.520900

Preprints | 2022

Molley T; Jiang S; Kopecky C; Ranaweera C; Jalandhra G; Rnjak-Kovacina J; Kilian K, 2022, Gas modulating microcapsules for spatiotemporal control of hypoxia, , http://dx.doi.org/10.1101/2022.09.02.506302

Preprints | 2020

Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey S; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill A; Gonzales-Aloy E; Kokkinos J; Gebski V; Turner N; Apte M; Davis TP; Morton JP; Haghighi K; Phillips PA, 2020, Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to SLC7A11 inhibition, , http://dx.doi.org/10.1101/2020.07.12.199638

Conference Presentations | 2019

Tan WT; Kopecky C; Manandhar B; Rye K-A; Cochran B, 2019, 'Skeletal Muscle Specific Deletion Of Abca1 And Abcg1 Impacts Body Composition And Metabolism And Is Age Dependent', presented at 87th European Atherosclerosis Society Congress, 26 May 2019, http://dx.doi.org/10.1016/j.atherosclerosis.2019.06.122

Preprints | 2018

Kopecky C; Pandzic E; Parmar A; Szajer J; Lee V; Dupuy A; Arthur A; Fok S; Whan R; Ryder WJ; Rye K-A; Cochran BJ, 2018, Translocator Protein Localises To CD11b+ Macrophages In Atherosclerosis, , http://dx.doi.org/10.1101/494377

Conference Abstracts | 2018

Kopecky C; Ryder WJ; Szajer J; Parmar A; Pandzic E; Rye K-A; Cochran BJ, 2018, 'THE TSPO RADIOLIGAND 18F-PBR111 AS A PRE-ATHEROSCLEROTIC LESION DETECTION AGENT', in Atherosclerosis Plus, Elsevier, CANADA, Toronto, Vol. 32, pp. 145 - 146, presented at International Symposium on Atherosclerosis (ISA), CANADA, Toronto, 09 June 2018 - 12 June 2018, http://dx.doi.org/10.1016/j.atherosclerosissup.2018.04.446

Conference Papers | 2018

Kopecky CM; Ryder WJ; Szajer J; Parmar A; Pandzic E; Rye KA; Cochran BJ, 2018, 'Translocator Protein as Novel Marker for Early Atherosclerosis', in ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, CA, San Francisco, presented at Scientific Sessions of the American-Heart-Association on Vascular Discovery - From Genes to Medicine, CA, San Francisco, 10 May 2018 - 12 May 2018, http://dx.doi.org/10.1161/atvb.38.suppl_1.222

2020 – 2021: Innovative nanomedicines to improve drug delivery and metabolic reprogramming in pancreatic cancer; Cancer Clinical Academic Group E/MCR Seed grant scheme (Primary Investigator)

2019 - 2021: MyoRobot automated Biomechatronics Technology for Higher Education and Teaching Using Virtual Skills Lab; Australia-Germany Joint Research Cooperation Scheme (Secondary Investigator)

2016 - 2020: Effect of empagliflozin on the renin-angiotensin system in patients with chronic kidney disease with and without type 2 diabetes (NCT03078101); Boehringer-Ingelheim Investigator-Initiated Study (Applicant and Secondary Investigator)

UNSW Sydney School of Medical Sciences Paper of the Month award (2019)
Travel grant of the Australian Atherosclerosis Society (2018)
Abstract Prize of the Austrian Diabetes Society (2017)
Young Investigator Fellowship of the European Society of Atherosclerosis (2016)
Clinical Science award of the Austrian Society of Transplantation, Transfusion and Genetics (2015)
Hans-Krister-Stummvoll prize of the Austrian Society of Nephrology (2014)

Evaluation of nanomedicine therapeutics in vitro and in vivo to demonstrate the functional impact of metabolic reprogramming in pancreatic cancer
Utilisation of state-of-the-art methodologies such as 3D lightsheet fluorescence microscopy to identify and characterise:

a. human pancreatic tumour morphology

b. different stages of atherosclerosis progression and the associated immune cell profile

Identification of key molecular pathways and structural features of impaired skeletal muscle metabolism in diabetes
Characterisation of molecular effects of anti-diabetic and antihypertensive therapies on renin-angiotensin system (RAS) regulation in diabetic kidney disease
Comprehensive profiling of the protein composition and cardioprotective properties of high-density lipoproteins in chronic inflammatory diseases with high cardiovascular risk

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Dr Chantal Kopecky