I am a currently a postdoc in the School of Chemistry at UNSW Sydney. Prior to this appointment, I held an Alexander von Humboldt Fellowship (2019-2020) at the University of Münster in Germany.
My research interests lie in innovating methods to self-assemble block copolymers into complex nanostructures. Some self-assembly concepts/topics that I specialise in include (i) polymersomes (polymer vesicles) shape transformation, (i) hierarchical self-assembly from the nm-to-µm length scale, (iii) inverted solution polymer morphologies such as cubosomes and hexosomes, and (iv) scalable manufacturing of polymer nanoparticles.
In addition to block copolymer self-assembly, I have extensive experience in soft matter electron microscopy (cryo-TEM, cryo-ET, 3D reconstructions, selective polymer staining) and a personal fascination in topological defects.
I am open to collaborations and peer review requests in any of the area of studies listed above.
Below are some of my recent selected publications (in no particular order):
Wong* et al. J. Am. Chem. Soc.2020, 142, 10989–10995
Paper on the discovery of topological defects in polymer hexosomes - https://pubs.acs.org/doi/abs/10.1021/jacs.0c02009
Wong et al. Angew. Chem. Int. Ed.2019, 58, 7335 –7340
Paper describing a methodology to encapsulate molecules into two separate compartments which are only tens of nanometres apart -https://onlinelibrary.wiley.com/doi/epdf/10.1002/anie.201901880
Wong* et al. Chem. Soc. Rev. 2019, 48, 4019-4035
Tutorial review on non-spherical polymersomes - https://pubs.rsc.org/en/content/articlelanding/2019/CS/C8CS00856F
Wong et al. Prog. Polym. Sci.2020, 102, 101211
Review on making internally ordered microparticles from block copolymers - https://www.sciencedirect.com/science/article/pii/S0079670020300046
Lovegrove JT; Humphreys BA; Wong CK; de Campo L; Wang A; Garvey CJ; Stenzel MH, 2024, 'Correction to Assembly of Multicompartment Glycopolymer Worms in Aqueous Solution (vol 56, pg 3195, 2023)', MACROMOLECULES, 57, pp. 3873 - 3873, http://dx.doi.org/10.1021/acs.macromol.4c00738
Journal articles | 2024
Wong CK; Lai RY; Stenzel MH, 2024, 'Polymersomes with micellar patches', Journal of Colloid and Interface Science, 671, pp. 449 - 456, http://dx.doi.org/10.1016/j.jcis.2024.05.177
Journal articles | 2023
Chen C; Wong CK; Gröschel AH, 2023, 'Mixtures of Acid- and Base-Functionalized Microparticles for One-Pot Cascade Reaction', Macromolecular Rapid Communications, 44, http://dx.doi.org/10.1002/marc.202300063
Journal articles | 2023
Lovegrove JT; Humphreys BA; Wong CK; de Campo L; Wang A; Garvey CJ; Stenzel MH, 2023, 'Assembly of Multicompartment Glycopolymer Worms in Aqueous Solution', Macromolecules, 56, pp. 3195 - 3203, http://dx.doi.org/10.1021/acs.macromol.2c02466
Journal articles | 2023
Wong CK; Lai RY; Stenzel MH, 2023, 'Dynamic metastable polymersomes enable continuous flow manufacturing', Nature Communications, 14, pp. 6237, http://dx.doi.org/10.1038/s41467-023-41883-6
Journal articles | 2022
Ganda S; Wong CK; Biazik J; Raveendran R; Zhang L; Chen F; Ariotti N; Stenzel MH, 2022, 'Macrophage-Targeting and Complete Lysosomal Degradation of Self-assembled Two-Dimensional Poly(ϵ-caprolactone) Platelet Particles', ACS Applied Materials and Interfaces, 14, pp. 35333 - 35343, http://dx.doi.org/10.1021/acsami.2c06555
Journal articles | 2021
Chen C; Janoszka N; Wong CK; Gramse C; Weberskirch R; Gröschel AH, 2021, 'Scalable and Recyclable All-Organic Colloidal Cascade Catalysts', Angewandte Chemie International Edition, 60, pp. 237 - 241, http://dx.doi.org/10.1002/anie.202008104
Journal articles | 2021
Chen C; Janoszka N; Wong CK; Gramse C; Weberskirch R; Gröschel AH, 2021, 'Skalierbare und wiederverwertbare organische Kolloide als Kaskadenkatalysatoren', Angewandte Chemie, 133, pp. 240 - 245, http://dx.doi.org/10.1002/ange.202008104
Journal articles | 2021
Ganda S; Wong CK; Stenzel MH, 2021, 'Corona-Loading Strategies for Crystalline Particles Made by Living Crystallization-Driven Self-Assembly', Macromolecules, 54, pp. 6662 - 6669, http://dx.doi.org/10.1021/acs.macromol.1c00643
Journal articles | 2021
Qiang X; Franzka S; Quintieri G; Dai X; Wong CK; Gröschel AH, 2021, 'Size-Controlled Formation of Polymer Janus Discs', Angewandte Chemie International Edition, 60, pp. 21668 - 21672, http://dx.doi.org/10.1002/anie.202105235
Journal articles | 2021
Qiang X; Franzka S; Quintieri G; Dai X; Wong CK; Gröschel AH, 2021, 'Size‐Controlled Formation of Polymer Janus Discs', Angewandte Chemie, 133, pp. 21836 - 21840, http://dx.doi.org/10.1002/ange.202105235
Journal articles | 2020
Gröschel TI; Wong CK; Haataja JS; Dias MA; Gröschel AH, 2020, 'Direct Observation of Topological Defects in Striped Block Copolymer Discs and Polymersomes', ACS Nano, 14, pp. 4829 - 4838, http://dx.doi.org/10.1021/acsnano.0c00718
Journal articles | 2020
Nghiem TL; Chakroun R; Janoszka N; Chen C; Klein K; Wong CK; Gröschel AH, 2020, 'pH-Controlled Hierarchical Assembly/Disassembly of Multicompartment Micelles in Water', Macromolecular Rapid Communications, 41, http://dx.doi.org/10.1002/marc.202000301
Journal articles | 2020
Tjandra KC; Forest CR; Wong CK; Alcantara S; Kelly HG; Ju Y; Stenzel MH; McCarroll JA; Kavallaris M; Caruso F; Kent SJ; Thordarson P, 2020, 'Modulating the Selectivity and Stealth Properties of Ellipsoidal Polymersomes through a Multivalent Peptide Ligand Display', Advanced Healthcare Materials, 9, http://dx.doi.org/10.1002/adhm.202000261
Journal articles | 2020
Wong CK; Heidelmann M; Dulle M; Qiang X; Förster S; Stenzel MH; Gröschel AH, 2020, 'Vesicular Polymer Hexosomes Exhibit Topological Defects', Journal of the American Chemical Society, 142, pp. 10989 - 10995, http://dx.doi.org/10.1021/jacs.0c02009
Journal articles | 2020
Wong CK; Qiang X; Müller AHE; Gröschel AH, 2020, 'Self-Assembly of block copolymers into internally ordered microparticles', Progress in Polymer Science, 102, http://dx.doi.org/10.1016/j.progpolymsci.2020.101211
Journal articles | 2019
Piloni A; Wong CK; Chen F; Lord M; Walther A; Stenzel MH, 2019, 'Surface roughness influences the protein corona formation of glycosylated nanoparticles and alter their cellular uptake', Nanoscale, 11, pp. 23259 - 23267, http://dx.doi.org/10.1039/c9nr06835j
Journal articles | 2019
Wong CK; Chen F; Walther A; Stenzel MH, 2019, 'Bioactive Patchy Nanoparticles with Compartmentalized Cargoes for Simultaneous and Trackable Delivery', Angewandte Chemie - International Edition, 58, pp. 7335 - 7340, http://dx.doi.org/10.1002/anie.201901880
Journal articles | 2019
Wong CK; Chen F; Walther A; Stenzel MH, 2019, 'Bioactive Patchy Nanoparticles with Compartmentalized Cargoes for Simultaneous and Trackable Delivery', Angewandte Chemie, 131, pp. 7413 - 7418, http://dx.doi.org/10.1002/ange.201901880
Journal articles | 2019
Wong CK; Martin AD; Floetenmeyer M; Parton RG; Stenzel MH; Thordarson P, 2019, 'Faceted polymersomes: A sphere-to-polyhedron shape transformation', Chemical Science, 10, pp. 2725 - 2731, http://dx.doi.org/10.1039/c8sc04206c
Journal articles | 2019
Wong CK; Stenzel MH; Thordarson P, 2019, 'Non-spherical polymersomes: Formation and characterization', Chemical Society Reviews, 48, pp. 4019 - 4035, http://dx.doi.org/10.1039/c8cs00856f
Journal articles | 2019
Wong S; Zhao J; Cao C; Wong CK; Kuchel RP; De Luca S; Hook JM; Garvey CJ; Smith S; Ho J; Stenzel MH, 2019, 'Just add sugar for carbohydrate induced self-assembly of curcumin', Nature Communications, 10, pp. 582, http://dx.doi.org/10.1038/s41467-019-08402-y
Journal articles | 2017
Wong CK; Mason AF; Stenzel MH; Thordarson P, 2017, 'Formation of non-spherical polymersomes driven by hydrophobic directional aromatic perylene interactions', Nature Communications, 8, pp. 1240, http://dx.doi.org/10.1038/s41467-017-01372-z
Journal articles | 2015
Jiang Y; Wong CK; Stenzel MH, 2015, 'An Oligonucleotide Transfection Vector Based on HSA and PDMAEMA Conjugation: Effect of Polymer Molecular Weight on Cell Proliferation and on Multicellular Tumor Spheroids', Macromolecular Bioscience, 15, pp. 965 - 978, http://dx.doi.org/10.1002/mabi.201500006
Journal articles | 2015
Wong CK; Laos AJ; Soeriyadi AH; Wiedenmann J; Curmi PMG; Gooding JJ; Marquis CP; Stenzel MH; Thordarson P, 2015, 'Polymersomes Prepared from Thermoresponsive Fluorescent Protein–Polymer Bioconjugates: Capture of and Report on Drug and Protein Payloads', Angewandte Chemie, 127, pp. 5407 - 5412, http://dx.doi.org/10.1002/ange.201412406
Journal articles | 2015
Wong CK; Laos AJ; Soeriyadi AH; Wiedenmann J; Curmi PMG; Gooding JJ; Marquis CP; Stenzel MH; Thordarson P, 2015, 'Polymersomes prepared from thermoresponsive fluorescent protein-polymer bioconjugates: Capture of and report on drug and protein payloads', Angewandte Chemie International Edition, 54, pp. 5317 - 5322, http://dx.doi.org/10.1002/anie.201412406