Associate Professor Christopher Marquis
Associate Professor

Associate Professor Christopher Marquis

University of Sydney; Bachelor of Science (Chemistry)

University of Sydney; Bachelor of Engineering (Chemical Engineering)

University of Sydney; Doctor of Philosophy (Bioprocess Engineering)

Deakin University; Graduate Diploma (Technology Management)

Science
School of Biotech & Biomolecular Science

Research Program

A/Prof Marquis trained as a biochemical engineer and has current interdisciplinary research projects across protein biotechnology and in the bio-nanotechnology interface. Current projects include developing recombinant enzymes for organohalide bioremediation, developing a bioprocess for a novel protein therapeutic, bioprocess development for therapeutic bacteriophage production, bioprocessing for plasmid DNA production and the generation of recombinant spider silks. 

In addition A/Prof Marquis is the Academic Director of the Recombinant Products Facility (www.proteins.unsw.edu.au), which houses research infrastructure for fermentation, cell culture, mid-stream and downstream processing for protein production, purification and characterisation. The facility also provides expertise in developing and optimising bioprocesses. The primary role of the Facility is to provide research support to the UNSW research community, however the facility provides contract services for the wider research community and also industry. The RPF has fermentation capacity to 20L and a variety of mid and downstream processing capabilities for the production and purification of proteins for research. In addition to running contract projects we have a number of internal initiatives to investigate and optimise bioprocesses.

Available projects can be viewed here

Professional Experience

  • 1994-ongoing: Lecturer, UNSW. Senior Lecturer from 2004, Associate Professor from 2016
  • Director, UNSW Recombinant Products Facility: http://www.proteins.unsw.edu.au/ 

Memberships

  • Member Ausbiotech Committee NSW
Phone
(+61 2) 9385 3898
Location
Room: 320A, Building D26, Level 3
  • Journal articles | 2018
    Faiz MB; Amal R; Marquis CP; Harry EJ; Sotiriou GA; Rice SA; Gunawan C, 2018, 'Nanosilver and the microbiological activity of the particulate solids versus the leached soluble silver', Nanotoxicology, vol. 12, pp. 263 - 273, http://dx.doi.org/10.1080/17435390.2018.1434910
    Journal articles | 2017
    Danta M; Barber DA; Zhang HP; Lee-Ng M; Baumgart SWL; Tsai VWW; Husaini Y; Saxena M; Marquis CP; Errington W; Kerr S; Breit SN; Brown DA, 2017, 'Macrophage inhibitory cytokine-1/growth differentiation factor-15 as a predictor of colonic neoplasia', Alimentary Pharmacology and Therapeutics, vol. 46, pp. 347 - 354, http://dx.doi.org/10.1111/apt.14156
    Journal articles | 2017
    Gunawan C; Marquis CP; Amal R; Sotiriou GA; Rice SA; Harry EJ, 2017, 'Widespread and Indiscriminate Nanosilver Use: Genuine Potential for Microbial Resistance', ACS Nano, vol. 11, pp. 3438 - 3445, http://dx.doi.org/10.1021/acsnano.7b01166
    Journal articles | 2017
    Healey RD; Lebhar H; Hornung S; Thordarson P; Marquis CP, 2017, 'An improved process for the production of highly purified recombinant thaumatin tagged-variants', Food Chemistry, vol. 237, pp. 825 - 832, http://dx.doi.org/10.1016/j.foodchem.2017.06.018
    Journal articles | 2016
    Jugder ; Welch J; Braidy N; Marquis CP, 2016, 'Construction and use of a Cupriavidus necator H16 soluble hydrogenase promoter', PeerJ, vol. 4, pp. e2269 - e2269, http://dx.doi.org/10.7717/peerj.2269
    Journal articles | 2016
    Jugder B-E; Lebhar H; Aguey-Zinsou K-F; Marquis CP, 2016, 'Production and purification of a soluble hydrogenase from Ralstonia eutropha H16 for potential hydrogen fuel cell applications', MethodsX, vol. 3, pp. 242 - 250, http://dx.doi.org/10.1016/j.mex.2016.03.005
    Journal articles | 2016
    Jugder BE; Ertan H; Bohl S; Lee M; Marquis CP; Manefield M, 2016, 'Organohalide respiring bacteria and reductive dehalogenases: Key tools in organohalide bioremediation', Frontiers in Microbiology, vol. 7, http://dx.doi.org/10.3389/fmicb.2016.00249
    Journal articles | 2016
    Liana AE; Chia EW; Marquis CP; Gunawan C; Gooding JJ; Amal R, 2016, 'Adsorption of T4 bacteriophages on planar indium tin oxide surface via controlled surface tailoring', Journal of Colloid and Interface Science, vol. 468, pp. 192 - 199, http://dx.doi.org/10.1016/j.jcis.2016.01.052
    Journal articles | 2015
    Collins AM; Wang Y; Roskin KM; Marquis CP; Jackson KJL, 2015, 'The mouse antibody heavy chain repertoire is germline-focused and highly variable between inbred strains', Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 370, http://dx.doi.org/10.1098/rstb.2014.0236
    Journal articles | 2015
    Jugder BE; Ertan H; Lee M; Manefield M; Marquis CP, 2015, 'Reductive Dehalogenases Come of Age in Biological Destruction of Organohalides', Trends in Biotechnology, vol. 33, pp. 595 - 610, http://dx.doi.org/10.1016/j.tibtech.2015.07.004
    Journal articles | 2015
    Wong CK; Laos AJ; Soeriyadi AH; Wiedenmann J; Curmi PMG; Gooding JJ; Marquis CP; Stenzel MH; Thordarson P, 2015, 'Polymersomes prepared from thermoresponsive fluorescent protein-polymer bioconjugates: Capture of and report on drug and protein payloads', Angewandte Chemie - International Edition, vol. 54, pp. 5317 - 5322, http://dx.doi.org/10.1002/anie.201412406
    Journal articles | 2014
    Hvasanov D; Nam EV; Peterson JR; Pornsaksit D; Wiedenmann J; Marquis CP; Thordarson P, 2014, 'One-pot synthesis of high molecular weight synthetic heteroprotein dimers driven by charge complementarity electrostatic interactions', Journal of Organic Chemistry, vol. 79, pp. 9594 - 9602, http://dx.doi.org/10.1021/jo501713t
    Journal articles | 2014
    Tsai VWW; Manandhar R; Jrøgensen SB; Lee-Ng KKM; Zhang HP; Marquis CP; Jiang L; Husaini Y; Lin S; Sainsbury A; Sawchenko PE; Brown DA; Breit SN, 2014, 'The anorectic actions of the TGFβ cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract', PLoS ONE, vol. 9, http://dx.doi.org/10.1371/journal.pone.0100370
    Journal articles | 2013
    Cumbo V; Baird AH; Moore R; Negris AP; Neilan BA; Salih A; van Oppen MJH; Wang Y; Marquis C, 2013, 'Chromera velia is Endosymbiotic in Larvae of the Reef Corals Acropora digitifera and A. tenuis', Protist, vol. 164, pp. 237 - 244, http://dx.doi.org/10.1016/j.protis.2012.08.003
    Journal articles | 2013
    Gunawan C; Dr WYT; Marquis C; Amal R, 2013, 'Induced Adaptation of Bacillus sp. to Antimicrobial Nanosilver', Small, vol. 9, pp. 3553 - 3560, http://dx.doi.org/10.1002/smll.201300761
    Journal articles | 2013
    Gunawan C; Sirimanoonphan A; Teoh WY; Marquis C; Amal R, 2013, 'Submicron and Nano Formulations of Titanium Dioxide and Zinc Oxide Stimulate Unique Cellular Toxicological Responses in the Green Microalga Chlamydomonas reinhardtii', Journal of Hazardous Materials, vol. 260, pp. 984 - 992, http://dx.doi.org/10.1016/j.jhazmat.2013.06.067
    Journal articles | 2013
    Gunawan C; Teoh WY; Ricardo ; Marquis C; Amal R, 2013, 'Zinc Oxide Nanoparticles Induce Cell Filamentation in Escherichia coli', Particle and Particle Systems Characterisation, vol. 30, pp. 375 - 380, http://dx.doi.org/10.1002/ppsc.201200152
    Journal articles | 2011
    Duong HTT; Marquis C; Whittaker M; Davis TP; Boyer CA, 2011, 'Acid degradable and biocompatible polymeric nanoparticles for the potential codelivery of therapeutic agents', Macromolecules, vol. 44, pp. 8008 - 8019, http://dx.doi.org/10.1021/ma201085z
    Journal articles | 2011
    Gunawan C; Teoh WY; Marquis C; Amal R, 2011, 'Cytotoxic Origin of Copper(II) Oxide Nanoparticles: Comparative Studies with Micron-Sized Particles, Leachate, and Metal Salts', ACS Nano, vol. 5, pp. 7214 - 7225, http://dx.doi.org/10.1021/nn2020248
    Journal articles | 2009
    Gunawan C; Teoh WY; Marquis C; Lifia L; Amal R, 2009, 'Reversible Antimicrobial Photoswitching in Nanosilver', Small, vol. 5, pp. 341 - 344, http://dx.doi.org/10.1002/small.200801202
    Journal articles | 2005
    Coleman H; Marquis C; Scott JA; Chin S; Amal R, 2005, 'Bactericidal effects of titanium dioxide-based photocatalysts', Chemical engineering journal, vol. 113, pp. 55 - 63, http://dx.doi.org/10.1016/j.cej.2005.07.015