Dr Claire Burley
Postdoctoral Fellow

Dr Claire Burley

PhD A Multimodal Investigation of Brain Health: Cerebral Blood Flow, Cognitive Performance and Quality of Life; University of Birmingham, UK

MSc Clinical Neuroscience; University College London, UK

BSc Psychology (with industrial placement, Oxford Health NHS Foundation Trust); Loughborough University, UK

Medicine & Health
Centre for Healthy Brain Ageing

Dr Claire Burley is interested in healthy ageing, measures of brain health (e.g., MRI and Doppler imaging, neuropsychiatric, cognitive and quality of life), changed behaviours, psychological symptoms, dementia risk factors, and improving care for people living with dementia using person-centred, non-pharmacological approaches. Dr Burley has two research/ teaching roles at the Faculty of Medicine and Health, UNSW Sydney, both involving dementia and brain health. One is based at the Centre for Healthy Brain Ageing (CHeBA), School of Psychiatry and the other is based at the Lifestyle Clinic, School of Health Sciences.

Centre for Healthy Brain Ageing (CHeBA), School of Psychiatry: 

Dr Burley's CHeBA project is focusing on improving care for people living with dementia in the hospital setting using person-centred, nonpharmacological, evidence-based approaches. This project received funding through a competitive NHMRC grant and Dr Burley is a CI. She manages the project with Professor Lynn Chenoweth. The study involves educating nursing, medical and allied health staff in person-centred concepts and approaches to care. These ultimately lead to improve quality of life for people living with dementia, reduced occurrence of neuropsychiatric symptoms, and lead to higher levels of staff satisfaction. Their team have shown that these approaches are effective in a hospital setting in a pilot study. Their current project is building on this work and a PhD student with extensive nursing experience is being supervised to develop online education packages and approaches that can be rolled out on a large scale across Australia.

The Lifestyle Clinic, School of Health Sciences:

Dr Burley's projects at the Lifestyle Clinic focus on improving physical and brain health using physical activity approaches provided by Accredited Exercise Physiologists. These projects include optimising exercise strategies for hypertension, diabetes, osteoporosis and osteoarthritis. These strategies aim to reduce pain, improve quality of life and reduce risk for falls and developing dementia. Two PhD students are being enrolled to support this work and Dr Burley is developing teaching materials for BSc Exercise Physiology students with a focus on the latest research into physical activity, dementia and brain health.

Other projects Dr Burley has recently completed include reviewing cost-effective approaches of person-centred care and other nonpharmacological approaches (Burley et al., 2020, International Psychogeriatrics), as misconceptions around costs are considered a barrier to implementing long-term beneficial change, particularly in residential care settings, a systematic review for approaches to reduce disinhibited behaviours in dementia (Burley et al. accepted Feb 2022, International Psychogeriatrics), a meta-analysis of nonpharmacological approaches that reduce symptoms of depression in dementia (under review, Ageing Research Reviews), a qualitative study investigating the views of people living with dementia towards changed behaviours that they experience (Burley et al., 2021, Frontiers in Psychiatry) and helpful/ unhelpful responses from others that people living with dementia find helpful (manuscript in preparation).

Mobile
+61 (0) 403 804 907
Phone
+61 (2) 9065 3510
  • Book Chapters | 2021
    Burley CV; Mullinger KJ; Thomas KN; Rendeiro C; Dehghani H; Lucas SJE, 2021, 'Imaging cerebral blood flow for brain health measurement', in Encyclopedia of Behavioral Neuroscience: Second Edition, Elsevier, pp. 126 - 135, http://dx.doi.org/10.1016/B978-0-12-819641-0.00157-2
  • Journal articles | 2022
    Burley CV; Burns K; Brodaty H, 2022, 'Pharmacological and nonpharmacological approaches to reduce disinhibited behaviors in dementia: A systematic review', International Psychogeriatrics, pp. 1 - 17, http://dx.doi.org/10.1017/S1041610222000151
    Journal articles | 2021
    Burley CV; Casey AN; Chenoweth L; Brodaty H, 2021, 'Reconceptualising Behavioral and Psychological Symptoms of Dementia: Views of People Living With Dementia and Families/Care Partners', Frontiers in Psychiatry, vol. 12, pp. 710703, http://dx.doi.org/10.3389/fpsyt.2021.710703
    Journal articles | 2021
    Burley CV; Chenoweth L; Casey ANS; Brodaty H, 2021, 'Changed behaviours associated with cognitive decline: Views of people living with dementia, families and healthcare professionals', Alzheimer's & dementia : the journal of the Alzheimer's Association, vol. 17, pp. e051963, http://dx.doi.org/10.1002/alz.051963
    Journal articles | 2021
    Burley CV; Francis ST; Thomas KN; Whittaker AC; Lucas SJE; Mullinger KJ, 2021, 'Contrasting Measures of Cerebrovascular Reactivity Between MRI and Doppler: A Cross-Sectional Study of Younger and Older Healthy Individuals', Frontiers in Physiology, vol. 12, http://dx.doi.org/10.3389/fphys.2021.656746
    Journal articles | 2021
    Burley CV; Francis ST; Whittaker AC; Mullinger KJ; Lucas SJE, 2021, 'Measuring resting cerebral haemodynamics using MRI arterial spin labelling and transcranial Doppler ultrasound: Comparison in younger and older adults', Brain and Behavior, vol. 11, http://dx.doi.org/10.1002/brb3.2126
    Journal articles | 2020
    Burley CV; Livingston G; Knapp MRJ; Wimo A; Norman R; Brodaty H, 2020, 'Time to invest in nonpharmacological interventions for behaviours and psychological symptoms associated with dementia', Alzheimer's & Dementia, vol. 16, http://dx.doi.org/10.1002/alz.042281
    Journal articles | 2020
    Burley CV; Livingston G; Knapp MRJ; Wimo A; Norman R; Brodaty H, 2020, 'Time to invest in prevention and better care of behaviors and psychological symptoms associated with dementia', International Psychogeriatrics, vol. 32, pp. 567 - 572, http://dx.doi.org/10.1017/S104161022000037X
    Journal articles | 2020
    Burley CV; Lucas RAI; Whittaker AC; Mullinger K; Lucas SJE, 2020, 'The CO2 stimulus duration and steady-state time point used for data extraction alters the cerebrovascular reactivity outcome measure', Experimental Physiology, vol. 105, pp. 893 - 903, http://dx.doi.org/10.1113/EP087883
    Journal articles | 2020
    Furlong RJ; Weaver SR; Sutherland R; Burley CV; Imi GM; Lucas RAI; Lucas SJE, 2020, 'Exercise-induced elevations in cerebral blood velocity are greater in running compared to cycling at higher intensities', Physiological Reports, vol. 8, pp. e14539, http://dx.doi.org/10.14814/phy2.14539
    Journal articles | 2020
    Gratton G; Weaver SR; Burley CV; Low KA; Maclin EL; Johns PW; Pham QS; Lucas SJE; Fabiani M; Rendeiro C, 2020, 'Dietary flavanols improve cerebral cortical oxygenation and cognition in healthy adults', Scientific Reports, vol. 10, http://dx.doi.org/10.1038/s41598-020-76160-9
    Journal articles | 2019
    Elhassan YS; Kluckova K; Fletcher RS; Schmidt MS; Garten A; Doig CL; Cartwright DM; Oakey L; Burley CV; Jenkinson N; Wilson M; Lucas SJE; Akerman I; Seabright A; Lai YC; Tennant DA; Nightingale P; Wallis GA; Manolopoulos KN; Brenner C; Philp A; Lavery GG, 2019, 'Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures', Cell Reports, vol. 28, pp. 1717 - 1728.e6, http://dx.doi.org/10.1016/j.celrep.2019.07.043
    Journal articles | 2018
    Segaert K; Lucas SJE; Burley CV; Segaert P; Milner AE; Ryan M; Wheeldon L, 2018, 'Higher physical fitness levels are associated with less language decline in healthy ageing', Scientific Reports, vol. 8, http://dx.doi.org/10.1038/s41598-018-24972-1
    Journal articles | 2017
    Burley CV; Mullinger K; Francis ST; Whittaker AC; Lucas SJE, 2017, '[IC‐P‐159]: A COMPARISON OF BRAIN IMAGING MODALITIES AND ANALYSIS APPROACHES FOR MEASURES OF CEREBROVASCULAR RESPONSIVENESS', Alzheimer's & Dementia, vol. 13, pp. P121 - P122, http://dx.doi.org/10.1016/j.jalz.2017.06.2534
    Journal articles | 2017
    Burley CV; Whittaker AC; Mullinger K; Lucas SJE, 2017, '[P1–610]: HIGHER AEROBIC FITNESS IMPROVES PERFORMANCE ON COGNITIVE TASKS AND MEASURES OF QUALITY OF LIFE: A CROSS‐SECTIONAL STUDY OF YOUNG AND OLD INDIVIDUALS', Alzheimer's & Dementia, vol. 13, pp. P529 - P530, http://dx.doi.org/10.1016/j.jalz.2017.06.626
    Journal articles | 2016
    Burley CV; Bailey DM; Marley CJ; Lucas SJE, 2016, 'Brain train to combat brain drain; focus on exercise strategies that optimize neuroprotection', Experimental Physiology, vol. 101, pp. 1178 - 1184, http://dx.doi.org/10.1113/EP085672
    Journal articles | 2010
    Horne JA; Burley CV, 2010, 'We know when we are sleepy: Subjective versus objective measurements of moderate sleepiness in healthy adults', Biological Psychology, vol. 83, pp. 266 - 268, http://dx.doi.org/10.1016/j.biopsycho.2009.12.011
  • Preprints | 2019
    Elhassan Y; Kluckova K; Fletcher R; Schmidt M; Garten A; Doig C; Cartwright D; Oakey L; Burley C; Jenkinson N; Wilson M; Lucas S; Akerman I; Seabright A; Lai Y-C; Tennant D; Nightingale P; Wallis G; Manolopoulos K; Brenner C; Philp A; Lavery G, 2019, Nicotinamide riboside augments the human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures in aged subjects: a placebo-controlled, randomized trial, http://dx.doi.org/10.1101/680462
    Preprints | 2018
    Segaert K; Lucas SJE; Burley CV; Segaert P; Milner AE; Ryan M; Wheeldon L, 2018, Higher physical fitness levels are associated with less language decline in healthy ageing
    Conference Papers | 2017
    Burley CV; Mullinger KJ; Francis ST; Phillips AC; Lucas SJE, 2017, 'Assessing Cerebrovascular Responsiveness: Comparing Functional Magnetic Resonance Imaging With Doppler Ultrasound', in MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, LIPPINCOTT WILLIAMS & WILKINS, Denver, CO, pp. 825 - 825, presented at Annual Meeting of the American-College-of-Sports-Medicine (ACSM), Denver, CO, 30 May 2017 - 03 June 2017, http://dx.doi.org/10.1249/01.mss.0000519215.31383.62
    Conference Papers | 2017
    Lucas SJE; Thomas K; Wright RL; Ramsay JRE; Medwell AL; Burley CV, 2017, 'Effect Of Aquatic-treadmill Training On Cerebrovascular Function In Community-dwelling Stroke Survivors: A Pilot Study', in MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, LIPPINCOTT WILLIAMS & WILKINS, Denver, CO, pp. 30 - 30, presented at Annual Meeting of the American-College-of-Sports-Medicine (ACSM), Denver, CO, 30 May 2017 - 03 June 2017, http://dx.doi.org/10.1249/01.mss.0000516896.38375.33
    Preprints |
    Parmenter B; Burley C; Stewart C; Whife J; Champion K; Osman B; Newton N; Green O; Wescott AB; Gardner LA; Visontay R; Birrell L; Bryant Z; Chapman C; Lubans DR; Sunderland M; Slade T; Thornton L, How well can your smartphone measure your physical activity levels? A systematic review of the measurement properties of smartphone approaches to assess physical activity in healthy young people. (Preprint), http://dx.doi.org/10.2196/preprints.39085
    Preprints |
    Segaert K; Lucas SJE; Burley CV; Segaert P; Milner AE; Ryan M; Wheeldon L, Higher physical fitness levels are associated with less language decline in healthy ageing, http://dx.doi.org/10.1101/197095

2022:

CI, Dementia Australia Research Foundation (DARF) Project Grant, $75,000. Towards better mental health of people living with dementia in Residential Aged Care: Co-design of a performance measurement tool to aid organisational governance.

2021:

CI, NHMRC DCRC World Class Research Grant, $600,000. Improving health outcomes, well-being and care for people living with dementia in a hospital setting.

2018:

Named researcher, Birmingham-Nottingham Strategic Collaboration Fund, £38,000. Contrasting measures of cerebral haemodynamics between MRI (ASL, BOLD & PCA) and Doppler ultrasound (TCD, Duplex Doppler).

2016:

CI, Cambridge Cognition Research Grant - Doctoral Researcher. A multimodal investigation of brain health: cerebral blood flow, cognitive performance and quality of life.

2021:

Alzheimer's Association International Conference (AAIC) Travel Fellowship (Registration & accommodation)

2020:

Alzheimer’s Disease International (ADI) Early Career Researcher Bursary (Invitation to present, registration)

2018:

Birmingham College LES Travel Award (£500)
Physiological Society Travel Award (£500)

2017:

Birmingham College LES Travel Award (£600)
Physiological Society Travel Award (£500)

2016:

Guarantors of Brain Travel Grant (£1,000)
Physiological Society Travel Award (£500)

2015:

U21 Research Scholarship, UBC, Canada (£1,500)
Birmingham Travel Scholarship (£1,000)
Birmingham College LES Travel Award (£1,000)
Physiological Society Travel Award (£500)

2014:

3-year PhD Studentship, University of Birmingham