Dr Danit Saks

Postdoctoral Fellow

PhD (Clinical Medicine), MRes (Biomedical Sciences), MBMSc, BSc (Neuroscience)

Medicine & Health

Centre for Healthy Brain Ageing

Dr Saks is a post-doctoral research fellow and study coordinator for the AusCADASIL study. She joined the Centre for Healthy Brain Ageing at University of New South Wales in January 2023 after completing her PhD in clinical medicine (Glaucoma) and Masters of Research in Biomedical Sciences (Alzheimer's Disease) at Macquarie University. She has research experience in the fields of neurodegeneration, neuroscience and vision science, with a focus on Alzheimer's disease, dementia, and glaucoma.

Phone

+61 2 9348 1658

E-mail

d.saks@unsw.edu.au

Location

Centre for Healthy Brain Ageing, Health Translation Hub, UNSW

Journal articles | 2026

Sachdev PS; Bentvelzen AC; Gustafson D; Hansra GK; Hosoki S; Jiang J; Lennon MJ; Moro MA; Saks DG; Samaras K; Kovacic JC; Kalaria R, 2026, 'Vascular Cognitive Impairment and Dementia: Clinical Features, Neuropathology, and Biomarkers', Journal of the American College of Cardiology, 87, pp. 52 - 76, http://dx.doi.org/10.1016/j.jacc.2025.11.008

Journal articles | 2025

Bentvelzen AC; Kochan NA; Saks DG; Chander RJ; Koncz R; Aam S; Alves GS; Briceno EM; Brodtmann A; Cerami C; Clancy U; Cysique L; Deary IJ; DeCarli C; Dodich A; Godefroy O; Jochems ACC; Jokinen H; Kang Y; Karayanidis F; Kessels RPC; Kyläheiko I; Lancaster K; Laukka EJ; Levine DA; Marseglia A; Pase MP; Peters R; Salmon DP; Salvadori E; Shirk SD; Stokes KA; Sudo FK; Summers MJ; Vandermorris S; Vasquez BP; Sachdev PS, 2025, 'Consensus-Harmonized Neuropsychological Assessment for Vascular Cognitive Impairment and Dementia', JAMA Network Open, http://dx.doi.org/10.1001/jamanetworkopen.2025.47948

Journal articles | 2025

Cristalli CAA; Rosales J; Gonzalez F; Selvaggi V; Alonso JM; López JI; Aguilar M; Kauffman M; Saks DG; Allegri R; Sevlever G; Chaves H; Cristalli DO; Calandri IL, 2025, 'Clinical Manifestations', Alzheimer S Dementia the Journal of the Alzheimer S Association, 21, pp. e101610, http://dx.doi.org/10.1002/alz70857_101610

Journal articles | 2025

Sachdev PS; Bentvelzen AC; Kochan NA; Jiang J; Hosoki S; Koncz R; Chander RJ; Saks D; Aben HP; Acosta D; Andersen P; Assal F; Bae HJ; Biessels GJ; Blacker D; Bordet R; Briceno EM; Brodaty H; Brodtmann A; Caramelli P; Castro-Costa E; Chabriat H; Chen C; Clancy U; Cysique L; Decarli C; Ding D; Duering M; Engelhardt E; Gauthier S; Geranmayeh F; Godefroy O; Gorelick P; Greenberg SM; Jelic V; Jokinen H; Kalaria RN; Krishna M; Lancaster K; De Leeuw FE; Lim JS; Marseglia A; Marta-Moreno J; O'Brien JT; Pantoni L; Pase MP; Pendlebury ST; Rosenberg G; Sabayan B; Salvadori E; Samaras K; Sebastian IA; Seshadri S; Smith EE; Srikanth V; Stokes K; Sudo FK; Sveikata L; Valenzuela M; Wallin A; Wardlaw JM; Xu Q, 2025, 'Revised Diagnostic Criteria for Vascular Cognitive Impairment and Dementia-The VasCog-2-WSO Criteria', JAMA Neurology, 82, pp. 1103 - 1112, http://dx.doi.org/10.1001/jamaneurol.2025.3242

Journal articles | 2025

Saks DG; Bentvelzen AC; Sachdev PS, 2025, 'Cognitive Impairment in CADASIL: A Systematic Review and Meta-Analysis of Current Evidence', Cerebral Circulation - Cognition and Behavior, 9, pp. 100455 - 100455, http://dx.doi.org/10.1016/j.cccb.2025.100455

Journal articles | 2025

Saks DG; Sachdev PS, 2025, 'Monogenic causes of cerebral small vessel disease- models for vascular cognitive impairment and dementia?', Current Opinion in Psychiatry, 38, pp. 112 - 118, http://dx.doi.org/10.1097/YCO.0000000000000978

Journal articles | 2024

Saks DG; Bajorek B; Catts VS; Bentvelzen AC; Jiang J; Wen W; Mather KA; Thalamuthu A; Huang-Lung J; Nivison-Smith L; Griffiths LR; Smith RA; Sexton A; James P; Jayasena T; Poljak A; Hansra GK; Hosoki S; Park A; Hillenbrand CM; van Wijngaarden P; Chander RJ; Humphrey S; Chen R; Kochan NA; Helman TJ; Levi C; Brodtmann A; O'Sullivan MJ; Markus R; Butcher K; Parsons M; Kovacic JC; Sachdev PS, 2024, 'The protocol for an observational Australian cohort study of CADASIL: The AusCADASIL study', CEREBRAL CIRCULATION-COGNITION AND BEHAVIOR, 6, http://dx.doi.org/10.1016/j.cccb.2024.100225

Journal articles | 2024

Saks DG; Schulz A; Qassim A; Marshall H; Hewitt A; MacGregor S; Craig JE; Graham SL, 2024, 'Genetic risk of glaucoma is associated with vascular and retinal nerve fibre wedge defects', Acta Ophthalmologica, 102, pp. e185 - e194, http://dx.doi.org/10.1111/aos.15775

Journal articles | 2024

Saks DG; Smith EE; Sachdev PS, 2024, 'National and international collaborations to advance research into vascular contributions to cognitive decline', Cerebral Circulation Cognition and Behavior, 6, http://dx.doi.org/10.1016/j.cccb.2023.100195

Journal articles | 2024

Shen T; Sheriff S; You Y; Jiang J; Schulz A; Francis H; Mirzaei M; Saks D; Palanivel V; Basavarajappa D; Chitranshi N; Gupta V; Wen W; Sachdev PS; Jia H; Sun X; Graham SL; Gupta VK, 2024, 'Brain-Derived Neurotrophic Factor Val66Met is Associated with Variation in Cortical Structure in Healthy Aging Subjects', Aging and Disease, 15, pp. 2315 - 2327, http://dx.doi.org/10.14336/AD.2024.0346

Journal articles | 2023

Sheriff S; Shen T; Abdal S; Saks D; Mirzaei M; Gupta V; Chitranshi N; You Y; Schultz A; Graham SL; Gupta V, 2023, 'Retinal thickness and vascular parameters using optical coherence tomography in Alzheimer's disease: a meta-analysis', Neural Regeneration Research, 18, pp. 2504 - 2513, http://dx.doi.org/10.4103/1673-5374.371380

Journal articles | 2023

Sheriff S; Shen T; Saks D; Schultz A; Francis H; Wen W; Jiang J; Mirzaei M; Gupta V; Fiatarone Singh M; Sachdev PS; Graham SL; Gupta V, 2023, 'The Association of APOE ε4 Allele with Retinal Layer Thickness and Microvasculature in Older Adults: Optic Nerve Decline and Cognitive Change Study', Journal of Clinical Medicine, 12, http://dx.doi.org/10.3390/jcm12196219

Journal articles | 2022

Saks D; Schulz A; Sheriff S; Shen T; Gupta V; Qassim A; Ridge B; Pham R; Craig J; Graham S, 2022, 'Quantification of localised vascular wedge-shaped defects in glaucoma', Clinical and Experimental Ophthalmology, 50, pp. 724 - 735, http://dx.doi.org/10.1111/ceo.14134

Journal articles | 2022

Shen T; Sheriff S; You Y; Jiang J; Schulz A; Francis H; Mirzaei M; Saks D; Chitranshi N; Gupta V; Singh MF; Klistorner A; Wen W; Sachdev P; Gupta VK; Graham SL, 2022, 'Evaluating associations of RNFL thickness and multifocal VEP with cognitive assessment and brain MRI volumes in older adults: Optic nerve decline and cognitive change (ONDCC) initiative', Aging Brain, 2, http://dx.doi.org/10.1016/j.nbas.2022.100049

Journal articles | 2022

Sheriff S; Shen T; Saks D; Chitranshi N; Schulz A; Graham S; Gupta V, 2022, 'Relationship of APOE ε4 allele and BDNF Val66Met polymorphism to retinal structural and vascular OCTA parameters in aging cohort: Optic nerve decline and cognitive change study', ACTA OPHTHALMOLOGICA, 100, http://dx.doi.org/10.1111/j.1755-3768.2022.0326

Journal articles | 2021

Abyadeh M; Gupta V; Chitranshi N; Gupta V; Wu Y; Saks D; Wander Wall R; Fitzhenry MJ; Basavarajappa D; You Y; Salekdeh GH; Haynes PA; Graham SL; Mirzaei M, 2021, 'Mitochondrial dysfunction in Alzheimer’s disease - a proteomics perspective', Expert Review of Proteomics, 18, pp. 295 - 304, http://dx.doi.org/10.1080/14789450.2021.1918550

Journal articles | 2021

Abyadeh M; Gupta V; Paulo JA; Gupta V; Chitranshi N; Godinez A; Saks D; Hasan M; Amirkhani A; McKay M; Salekdeh GH; Haynes PA; Graham SL; Mirzaei M, 2021, 'A proteomic view of cellular and molecular effects of cannabis', Biomolecules, 11, http://dx.doi.org/10.3390/biom11101411

Journal articles | 2021

Chitranshi N; Kumar A; Sheriff S; Gupta V; Godinez A; Saks D; Sarkar S; Shen T; Mirzaei M; Basavarajappa D; Abyadeh M; Singh SK; Dua K; Zhang KYJ; Graham SL; Gupta V, 2021, 'Identification of novel cathepsin b inhibitors with implications in alzheimer’s disease: Computational refining and biochemical evaluation', Cells, 10, http://dx.doi.org/10.3390/cells10081946

Journal articles | 2020

Saks D; Schulz A; Craig J; Graham S, 2020, 'Determination of retinal nerve fibre layer and ganglion cell/inner plexiform layers progression rates using two optical coherence tomography systems: The PROGRESSA study', Clinical and Experimental Ophthalmology, 48, pp. 915 - 926, http://dx.doi.org/10.1111/ceo.13826

Journal articles | 2018

Saks D; Naismith SL; LaMonica H; Mowszowski L; Pye J; Lewis SJG; Hickie IB; Grunstein R; Duffy SL, 2018, 'P1‐653: UNDERSTANDING THE RELATIONSHIP BETWEEN PHYSICAL ACTIVITY, DEPRESSIVE SYMPTOMS AND SLEEP QUALITY IN OLDER ADULTS AT‐RISK FOR DEMENTIA', Alzheimer's & Dementia, 14, http://dx.doi.org/10.1016/j.jalz.2018.06.665
Conference Papers | 2025

Saks DG; Sachdev PS; Team A, 2025, '3538 Clinical profile of CADASIL: a preliminary case series from AusCADASIL', in Poster Abstracts, BMJ Publishing Group Ltd, pp. A34.3 - A35, presented at ANZAN Annual Scientific Meeting 2025 Abstracts, http://dx.doi.org/10.1136/bmjno-2025-anzan.93

Conference Posters | 2024

Saks DG; Sachdev PS; Group ACS, 2024, 'Improving the global understanding of CADASIL- a monogenic cause of vascular dementia', Vol. 20, pp. e088571 - e088571, http://dx.doi.org/10.1002/alz.088571

Conference Abstracts | 2022

Pham R; Marshall H; Kolovos A; Qassim A; Mullany S; Saks D; To M-S; Agar A; Galanopoulos A; Landers J; Healey PR; Graham SL; Hewitt AW; Casson R; MacGregor S; Siggs OM; Carneiro G; Craig JE; Palmer LJ, 2022, 'Associations between deep learning segmented macular optical coherence tomography cell layer thicknesses and primary open-angle glaucoma outcomes in the PROGRESSA study', in CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, WILEY, Vol. 49, pp. 913 - 914, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000721587100203&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2022

Saks D; Qassim A; Marshall H; Hewitt A; MacGregor S; Schulz A; Graham S; Craig J, 2022, 'Genetic risk of glaucoma is associated with focal patterns of vascular loss', in CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, WILEY, pp. 925 - 925, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000876646500074&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2022

Saks D; Schulz A; Craig J; Graham S, 2022, 'Dynamic and static retinal vessel analysis in primary open-angle glaucoma', in CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, WILEY, pp. 924 - 924, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000876646500072&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2022

Saks DG; Schulz A; Qassim A; Ridge B; Pham R; Sheriff S; Shen T; Gupta V; Craig JE; Graham SL, 2022, 'Clinical update on vascular changes in glaucoma', in CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, WILEY, pp. 851 - 851, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000721587100064&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2022

Sheriff S; Shen T; Saks D; Schulz A; Graham S; Gupta V, 2022, 'Influence of the APOE epsilon 4 allele on retinal nerve fibre layer thickness and optical coherence tomography angiography parameters in healthy aging: Optic nerve decline and cognitive change', in CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, WILEY, pp. 962 - 962, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000876646500163&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers | 2021

Saks D; Schulz A; Graham SL, 2021, 'Quantifi cation of Localised Wedge-Shaped Vessel Defects in Glaucoma', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, ELECTR NETWORK, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), ELECTR NETWORK, 01 May 2021 - 07 May 2021

Conference Papers | 2019

Saks D; Schulz A; Craig J; Graham S, 2019, 'Comparison of RNFL and GCLIPL thicknesses and progression characteristics using two OCT systems: The PROGRESSA Study', in CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, WILEY, pp. 119 - 119, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000493279000198&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

1. Title: From Imaging to Insight: Advancing Retinal Disease Detection with Hyperspectral Technology at UNSW

Investigators: Angelica Ly, Jessie Huang-Lung, Lisa Keay, Lisa Nivison-Smith, Matt Trinh, Rene Cheung, Nicole Carnt, Andrew John White, Maria Markoulli, Danit Saks, Henry Brodaty, Perminder Sachdev, Matthew Kiernan, Imran Razzak, Mary-Anne Williams

Scheme:UNSW Research Infrastructure Scheme

Amount: $131,499.00

UNSW School of Clinical Medicine Travel Bursary 2024: $1000
Kwan Fung and Yuet Ying Fung Healthy Brain Ageing Research Award 2024: $4000

My Research Supervision

PhD

Honours

ILP

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