Dr David   Tsai
Senior Lecturer

Dr David Tsai

  • PhD (Biomedical Engineering), 2012, University of New South Wales
  • MBiomedE, 2007, University of New South Wales
  • BE (Software, Honours 1st Class), 2007 University of New South Wales
Engineering
Grad Sch: Biomedical Eng

Dr David Tsai is a Senior Lecturer at the Graduate School of Biomedical Engineering and at the School of Electrical Engineering & Telecommunications. His research focuses on developing neurotechnologies for interacting with the brain at scale, with high spatiotemporal resolution and with reduced invasiveness.

Visit his lab's website for more information: https://biomicrosyslab.org.

Phone
+61 2 9065 8230
Location
Room 1003, Level 1, Bioscience South (E26)

Publications

  • Book Chapters | 2021
    Dr David Tsai
    Guo T; Shivdasani MN; Tsai D; Ayton LN; Rathbun DL; Lovell NH, 2021, 'Visual Prostheses: Neuroengineering Handbook', in Handbook of Neuroengineering, Springer Singapore, pp. 1 - 46, http://dx.doi.org/10.1007/978-981-15-2848-4_31-2
    Book Chapters | 2020
    Dr David Tsai
    Guo T; Tsai D; Bai S; Shivdasani M; Muralidharan M; Li L; Dokos S; Lovell N, 2020, 'Insights from Computational Modelling: Selective Stimulation of Retinal Ganglion Cells', in Brain and Human Body Modeling 2020, Springer Nature, http://dx.doi.org/10.1007/978-3-030-45623-8_13
  • Journal articles | 2020
    Dr David Tsai
    Muralidharan M; Guo T; Shivdasani MN; Tsai D; Fried S; Li L; Dokos S; Morley JW; Lovell NH, 2020, 'Neural activity of functionally different retinal ganglion cells can be robustly modulated by high-rate electrical pulse trains', Journal of Neural Engineering, vol. 17, pp. 045013, http://dx.doi.org/10.1088/1741-2552/ab9a97
    Journal articles | 2020
    Dr David Tsai
    Periyanagounder D; Wei T; Li T; Lin C; Gonçalves TP; Fu H; Tsai D; Ke J; Kuo H; Huang K; Lu N; Fang X; He J, 2020, 'Organic Semiconductors: Fast‐Response, Highly Air‐Stable, and Water‐Resistant Organic Photodetectors Based on a Single‐Crystal Pt Complex (Adv. Mater. 2/2020)', Advanced Materials, vol. 32, pp. 2070015 - 2070015, http://dx.doi.org/10.1002/adma.202070015
    Journal articles | 2019
    Dr David Tsai
    Guo T; Tsai D; Yang CY; Al Abed A; Twyford P; Fried SI; Morley JW; Suaning GJ; Dokos S; Lovell NH, 2019, 'Mediating retinal ganglion cell spike rates using high-frequency electrical stimulation', Frontiers in Neuroscience, vol. 13, http://dx.doi.org/10.3389/fnins.2019.00413
    Journal articles | 2019
    Dr David Tsai
    Periyanagounder D; Wei T-C; Li T-Y; Lin C-H; Goncalves TP; Fu H-C; Tsai D-S; Ke J-J; Kuo H-W; Huang K-W; Lu N; Fang X; He J-H, 2019, 'Fast-Response, Highly Air-Stable, and Water-Resistant Organic Photodetectors Based on a Single-Crystal Pt Complex', ADVANCED MATERIALS, vol. 32, http://dx.doi.org/10.1002/adma.201904634
    Journal articles | 2019
    Dr David Tsai
    Guo T; Tsai D; Yang CY; Al Abed A; Twyford P; Fried S, 2019, 'Mediating Retinal Ganglion Cell Spike Rates Using High-Frequency Electrical Stimulation (vol 13, 413, 2019)', FRONTIERS IN NEUROSCIENCE, vol. 13, http://dx.doi.org/10.3389/fnins.2019.00910
    Journal articles | 2018
    Dr David Tsai
    Yang CY; Tsai D; Guo T; Dokos S; Suaning G; Morley JM; Lovell N, 2018, 'Differential Electrical Responses in Retinal Ganglion Cell Subtypes: Effects of Synaptic Blockade and Stimulating Electrode Location', Journal of Neural Engineering, vol. 15, http://dx.doi.org/10.1088/1741-2552/aac315
    Journal articles | 2018
    Dr David Tsai
    Guo T; Yang CY; Tsai D; Muralidharan M; Suaning G; Morley J; Dokos S; Lovell N, 2018, 'Closed-Loop Efficient Searching of Optimal Electrical Stimulation Parameters for Preferential Excitation of Retinal Ganglion Cells', Frontiers in Neuroscience, vol. 12, http://dx.doi.org/10.3389/fnins.2018.00168
    Journal articles | 2018
    Dr David Tsai
    Tsai D; Yuste R; Shepard KL, 2018, 'Correction: Statistically reconstructed multiplexing for very dense, high-channel-count acquisition systems (IEEE Transactions on Biomedical Circuits and Systems (2018) 8:1 (13-23))', IEEE Transactions on Biomedical Circuits and Systems, vol. 12, pp. 1215 - 1216, http://dx.doi.org/10.1109/TBCAS.2018.2851843
    Journal articles | 2018
    Dr David Tsai
    Tsai D; Sawyer D; Bradd A; Yuste R; Shepard KL, 2018, 'Addendum: A very large-scale microelectrode array for cellular-resolution electrophysiology', Nature Communications, vol. 9, http://dx.doi.org/10.1038/s41467-018-06969-6
    Journal articles | 2017
    Dr David Tsai
    Tsai D; Yuste R; Shepard K, 2017, 'Statistically Reconstructed Multiplexing for Very Dense, High-Channel-Count Acquisition Systems', IEEE Transactions on Biomedical Circuits and Systems, vol. 12, pp. 13 - 23, http://dx.doi.org/10.1109/TBCAS.2017.2750484
    Journal articles | 2017
    Dr David Tsai
    Tsai D; Sawyer D; Bradd A; Yuste R; Shepard K, 2017, 'A very large-scale microelectrode array for cellular- resolution electrophysiology', Nature Communications, vol. 8, pp. 1802 - 1802, http://dx.doi.org/10.1038/s41467-017-02009-x
    Journal articles | 2017
    Dr David Tsai
    Jayant K; Hirtz JJ; Plante IJL; Tsai DM; De Boer WDAM; Semonche A; Peterka DS; Owen JS; Sahin O; Shepard KL; Yuste R, 2017, 'Targeted intracellular voltage recordings from dendritic spines using quantum-dot-coated nanopipettes', Nature Nanotechnology, vol. 12, pp. 335 - 342, http://dx.doi.org/10.1038/nnano.2016.268
    Journal articles | 2017
    Dr David Tsai
    Tsai D; Morley JW; Suaning GJ; Lovell NH, 2017, 'Survey of electrically evoked responses in the retina-stimulus preferences and oscillation among neurons', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/s41598-017-14357-1
    Journal articles | 2016
    Dr David Tsai
    Guo T; Tsai D; Morley JW; Suaning GJ; Kameneva T; Lovell NH; Dokos S, 2016, 'Electrical activity of on and off retinal ganglion cells: A modelling study', Journal of Neural Engineering, vol. 13, http://dx.doi.org/10.1088/1741-2560/13/2/025005
    Journal articles | 2015
    Dr David Tsai
    Tsai D; Choi J; Aklimi E; Shi C; Krishnaswamy H; Shepard K, 2015, 'Matching the power, voltage, and size of biological systems: a nW–scale, 0.023–mm3 pulsed 33–GHz radio trans- mitter operating from a 5kT/q–supply voltage', IEEE Transactions on Circuits and Systems, vol. 62, pp. 1950 - 1958, http://dx.doi.org/10.1109/TCSI.2015.2426958
    Journal articles | 2014
    Dr David Tsai
    Guo T; Tsai D; Bai S; Morley JW; Suaning GJ; Lovell NH; Dokos S, 2014, 'Understanding the retina: A review of computational models of the retina from the single cell to the network level', Critical Reviews in Biomedical Engineering, vol. 42, pp. 419 - 436, http://dx.doi.org/10.1615/CritRevBiomedEng.2014011732
    Journal articles | 2013
    Dr David Tsai
    Matteucci PB; Chen SC; Tsai D; Dodds CWD; Dokos S; Morley JW; Lovell NH; Suaning GJ, 2013, 'Current steering in retinal stimulation via a quasimonopolar stimulation paradigm', Investigative Ophthalmology and Visual Science, vol. 54, pp. 4307 - 4320, http://dx.doi.org/10.1167/iovs.13-11653
    Journal articles | 2012
    Dr David Tsai
    Tsai D; Chen S; Protti DA; Morley JW; Suaning GJ; Lovell NH, 2012, 'Responses of Retinal Ganglion Cells to Extracellular Electrical Stimulation, from Single Cell to Population: Model-Based Analysis', PLoS ONE, vol. 7, pp. 1 - 16, http://dx.doi.org/10.1371/journal.pone.0053357
    Journal articles | 2011
    Dr David Tsai
    Tsai D; Morley JW; Suaning GJ; Lovell NH, 2011, 'Frequency-dependent reduction of voltage-gated sodium current modulates retinal ganglion cell response rate to electrical stimulation', Journal of Neural Engineering, vol. 8, pp. Article number: 066007, http://dx.doi.org/10.1088/1741-2560/8/6/066007
    Journal articles | 2009
    Dr David Tsai
    Tsai D; Morley JW; Suaning GJ; Lovell NH, 2009, 'Direct activation and temporal response properties of rabbit retinal ganglion cells following subretinal stimulation', Journal of Neurophysiology, vol. 102, pp. 2982 - 2993, http://dx.doi.org/10.1152/jn.00545.2009
    Journal articles | 2009
    Dr David Tsai
    Tsai D; Morley JW; Suaning GJ; Lovell NH, 2009, 'A wearable real-time image processor for a vision prosthesis', Computer Methods and Programs in Biomedicine, vol. 95, pp. 258 - 269, http://dx.doi.org/10.1016/j.cmpb.2009.03.009
  • Conference Papers | 2021
    Dr David Tsai
    Sy L; Hoang TT; Bussu M; Thai MT; Phan PT; Low H; Brodie MA; Tsai D; Lovell N; Do TN, 2021, 'M-SAM: Miniature and Soft Artificial Muscle-Driven Wearable Robotic Fabric Sleeve for Upper Limb Augmentation', Yale, USA, presented at The 4th IEEE International Conference on Soft Robotics (Robosoft 2021), Yale, USA, 12 April 2021 - 16 March 2021
    Conference Papers | 2020
    Dr David Tsai
    Lin Q; Shivdasani MN; Tsai D; Chang YC; Jayaprakash N; Zanos S; Lovell NH; Dokos S; Guo T, 2020, 'A Computational Model of Functionally-distinct Cervical Vagus Nerve Fibers', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 2475 - 2478, http://dx.doi.org/10.1109/EMBC44109.2020.9175855
    Conference Papers | 2020
    Dr David Tsai
    Muralidharan M; Guo T; Shivdasani MN; Tsai D; Fried S; Cameron M; Morley JW; Dokos S; Lovell NH, 2020, 'Towards Controlling Functionally-Distinct Retinal Ganglion Cells in Degenerate Retina', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 3598 - 3601, http://dx.doi.org/10.1109/EMBC44109.2020.9176595
    Conference Papers | 2018
    Dr David Tsai
    Guo T; Tsai ; Muralidharan ; Suaning ; Morley ; Dokos ; Lovell , 2018, 'Computational models and tools for developing sophisticated stimulation strategies for retinal neuroprostheses', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Engineering in Medicine and Biology Society (EMBC), 2018 Annual International Conference of the IEEE., Honolulu, US, pp. 2248 - 2251, presented at Engineering in Medicine and Biology Society (EMBC), 2018 Annual International Conference of the IEEE., Honolulu, US, 18 July 2018 - 22 July 2018, http://dx.doi.org/10.1109/EMBC.2018.8512748
    Conference Papers | 2017
    Dr David Tsai
    Guo T; Barriga-Rivera A; Suaning G; Tsai D; Morley J; Dokos S; Lovell N, 2017, 'Mimicking Natural Neural Encoding through Retinal Electrostimulation', in International IEEE/EMBS Conference on Neural Engineering, NER, Shanghai, pp. 284 - 287, presented at 2017 Annual International Conference of the IEEE on Neural Engineering, Shanghai, 25 May 2017 - 28 May 2017, http://dx.doi.org/10.1109/NER.2017.8008346
    Patents | 2017
    Dr David Tsai
    Tsai D; Morley J; Suaning G; Lovell N, 2017, Stimulation method for maintaining the re- sponsiveness of electrically excitable cells to repeated electrical stimulation, Patent No. 9,669,213 B2
    Patents | 2017
    Dr David Tsai
    Lovell N; Morley J; Suaning G; Tsai D, 2017, Stimulation method for maintaining responsiveness of cells, Australia, Patent No. 2012211030, http://pericles.ipaustralia.gov.au/ols/auspat/applicationDetails.do?applicationNo=2012211030
    Conference Papers | 2016
    Dr David Tsai
    Yang C; Tsai D; Guo T; Suaning G; Dokos S; Morley J; Lovell N, 2016, 'High Frequency Electrical Stimulation: the Effect of Spatial Location on Retinal Ganglion Cell Responses In vitro', in Proceedings of the 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Engineering in Medicine and Biology Society (EMBC), 2016 Annual International Conference of the IEEE., Florida USA, presented at Engineering in Medicine and Biology Society (EMBC), 2016 Annual International Conference of the IEEE., Florida USA, 16 August 2016 - 20 August 2016
    Conference Papers | 2015
    Dr David Tsai
    Tsai D; John E; Chari T; Yuste R; Shepard K, 2015, 'High–channel–count, high–density microelectrode array for closed–loop investigation of neuronal networks,', in Proceedings of the 37th Annual International Conference of the IEEE EMBS, Milan, Italy, pp. 7510 - 7513, presented at Annual International Conference of the IEEE EMBS, Milan, Italy, 25 August 2015 - 29 August 2015, http://dx.doi.org/10.1109/EMBC.2015.7320129
    Conference Papers | 2015
    Dr David Tsai
    Guo T; Lovell NH; Tsai D; Twyford P; Fried S; Morley JW; Suaning GJ; Dokos S, 2015, 'Optimizing retinal ganglion cell responses to high-frequency electrical stimulation strategies for preferential neuronal excitation', in International IEEE/EMBS Conference on Neural Engineering, NER, pp. 252 - 255, http://dx.doi.org/10.1109/NER.2015.7146607
    Conference Papers | 2015
    Dr David Tsai
    Bai S; Guo T; Tsai D; Morley JW; Suaning GJ; Lovell NH; Dokos S, 2015, 'Influence of retinal ganglion cell morphology on neuronal response properties - A simulation study', in International IEEE/EMBS Conference on Neural Engineering, NER, pp. 679 - 682, http://dx.doi.org/10.1109/NER.2015.7146714
    Conference Papers | 2015
    Dr David Tsai
    Yang CY; Woolley AJ; Tsai D; Suaning GJ; Morley JW; Lovell NH, 2015, 'Calcium imaging of retinal ganglion cell dendritic responses to extracellular microelectrode stimulation', in International IEEE/EMBS Conference on Neural Engineering, NER, pp. 438 - 441, http://dx.doi.org/10.1109/NER.2015.7146653
    Conference Papers | 2014
    Dr David Tsai
    Choi J; Aklimi E; Roseman J; Tsai D; Krishnaswamy H; Shepard KL, 2014, 'Matching the power density and potentials of biological systems: A 3.1-nW, 130-mV, 0.023-mm3 pulsed 33-GHz radio transmitter in 32-nm SOI CMOS', in Proceedings of the IEEE 2014 Custom Integrated Circuits Conference, CICC 2014, http://dx.doi.org/10.1109/CICC.2014.6945985
    Conference Papers | 2014
    Dr David Tsai
    Guo T; Tsai D; Morley JW; Suaning GJ; Lovell NH; Dokos S, 2014, 'The Unique Characteristics of ON and OFF Retinal Ganglion Cells: A Modeling Study', in 2014 36TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), IEEE, Chicago, IL, pp. 6072 - 6075, presented at 36th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society (EMBC), Chicago, IL, 26 August 2014 - 30 August 2014, http://dx.doi.org/10.1109/EMBC.2014.6945020
    Conference Papers | 2014
    Dr David Tsai
    Guo T; Lovell NH; Tsai D; Twyford P; Fried S; Morley JW; Suaning GJ; Dokos S, 2014, 'Selective activation of ON and OFF retinal ganglion cells to high-frequency electrical stimulation: a computational modeling study', in Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, pp. 6108 - 6111, http://dx.doi.org/10.1109/EMBC.2014.6945023
    Conference Papers | 2013
    Dr David Tsai
    Guo T; Tsai D; Sovilj S; Morley JW; Suaning GJ; Lovell NH; Dokos S, 2013, 'Influence of active dendrites on firing patterns in a retinal ganglion cell model', in Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, pp. 4557 - 4560, http://dx.doi.org/10.1109/EMBC.2013.6610561
    Conference Papers | 2013
    Dr David Tsai
    Guo T; Tsai D; Morley JW; Suaning GJ; Lovell NH; Dokos S, 2013, 'Cell-specific modeling of retinal ganglion cell electrical activity', in Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, pp. 6539 - 6542, http://dx.doi.org/10.1109/EMBC.2013.6611053
    Conference Papers | 2012
    Dr David Tsai
    Guo T; Tsai D; Suaning GJ; Lovell NH; Dokos S, 2012, 'Modeling Normal and Rebound Excitation in Mammalian Retinal Ganglion Cells', in 34th Annual International Conference of the IEEE EMBS, IEEE, San Diego, California, USA, pp. 5506 - 5509, presented at 34th Annual International Conference of the IEEE EMBS, San Diego, California, USA, 28 August 2012 - 01 September 2012, http://dx.doi.org/10.1109/EMBC.2012.6347241
    Conference Papers | 2011
    Dr David Tsai
    Tsai D; Morley JW; Suaning GJ; Lovell NH, 2011, 'Responses of starburst amacrine cells to prosthetic stimulation of the retina', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, IEEE, Piscataway, NJ, United States, pp. 1053 - 1056, presented at 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011, Boston, Massachusetts USA, 30 August 2011 - 03 September 2011, http://dx.doi.org/10.1109/IEMBS.2011.6090245
    Conference Papers | 2011
    Dr David Tsai
    Tsai D; Morley JW; Suaning GJ; Lovell NH, 2011, 'Sodium channel inactivation reduces retinal ganglion cell responsiveness to repetitive prosthetic stimulation', in 2011 5th International IEEE/EMBS Conference on Neural Engineering, NER 2011, IEEE, USA, pp. 550 - 553, presented at 5th International IEEE/EMBS Conference on Neural Engineering, NER 2011, Cancun, Mexico, 27 April 2011 - 01 May 2011, http://dx.doi.org/10.1109/NER.2011.5910607
    Conference Papers | 2010
    Dr David Tsai
    Suaning GJ; Kisban S; Chen SC; Preston P; Dodds C; Tsai D; Matteucci P; H S; Morley JW; Lovell NH; Paul O; Stieglitz T; Rutherford P, 2010, 'Discrete cortical responses from multi-site supra-choroidal electrical stimulation in the feline retina', in IEEE Engineering in Medicine and Biology Society. Conference Proceedings, IEEE Society, USA, pp. 5879 - 5882, presented at The 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2010), Buenos Aires, Argentina
    Conference Papers | 2009
    Dr David Tsai
    Tsai D; Morley JW; Suaning GJ; Lovell NH, 2009, 'Direct activation of retinal ganglion cells with subretinal stimulation.', in Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, pp. 618 - 621

Awards

Grants

Past and present fundings from the following sources are gratefully acknowledged:

  • Australian Research Data Commons; ARDC (co-CI)
  • National Health and Medical Research Council; NHMRC (sole-CI and co-CI)
  • Kavli Foundation (sole-CI)
  • UNSW (co-CI)

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