Professor David Ziegler

Conjoint Professor

MBBS (Hons 1), BSc(Med), FRACP, MD(Res)

Medicine & Health
School of Clinical Medicine

Prof David Ziegler is a Senior Staff Specialist in the Kids Cancer Centre at Sydney Children’s Hospital and has expertise in neuro-oncology and early phase clinical trials.  Prof Ziegler completed his clinical training in paediatric haematology and oncology at Sydney Children’s Hospital and as a Fulbright Scholar at the Dana Farber Cancer Institute, Harvard Medical School and Children’s Hospital Boston.  He is a Conjoint Professor at the University of New South Wales and a Group Leader at the Children’s Cancer Institute (CCI), where his preclinical research focuses on novel therapies for childhood brain tumours. He leads the neuro-oncology and clinical trials programs at the Kids Cancer Centre, Sydney Children's Hospital. He is Director of the Kids Cancer Alliance – a translational research program developed with the support of the Cancer Institute NSW.
 

Phone
+61-2-93821730
  • Journal articles | 2023
    Ajuyah P; Mayoh C; Lau LMS; Barahona P; Wong M; Chambers H; Valdes-Mora F; Senapati A; Gifford AJ; D’Arcy C; Hansford JR; Manoharan N; Nicholls W; Williams MM; Wood PJ; Cowley MJ; Tyrrell V; Haber M; Ekert PG; Ziegler DS; Khuong-Quang DA, 2023, 'Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes', Scientific Reports, 13, pp. 3775, http://dx.doi.org/10.1038/s41598-023-30395-4
    Journal articles | 2023
    Daly R; Hetherington K; Hazell E; Wadling BR; Tyrrell V; Tucker KM; Marshall GM; Ziegler DS; Lau LMS; Trahair TN; O’Brien TA; Collins K; Gifford AJ; Haber M; Pinese M; Malkin D; Cowley MJ; Karpelowsky J; Drew D; Jacobs C; Wakefield CE, 2023, 'Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial', Journal of Personalized Medicine, 13, pp. 1033 - 1033, http://dx.doi.org/10.3390/jpm13071033
    Journal articles | 2023
    Daniel P; Sun CX; Bradshaw G; Shi H; Loi M; Chew N; Parackal S; Tsui V; Liang Y; Koptyra M; Adjumain S; Sun C; Chong WC; Fernando D; Drinkwater C; Tourchi M; Habarakada D; Carvalho D; Storm PB; Baubet V; Sayles LC; Fernandez E; Zhukova N; Dun MD; Ludlow LE; Day B; Stringer BW; Neeman N; Rubens JA; Raabe EH; Vinci M; Tyrrell V; Fletcher JI; Ekert PG; Dumevska B; Ziegler DS; Tsoli M; Sulaiman NFS; Loh AHP; Low SYY; Sweet-Cordero EA; Monje M; Resnick A; Jones C; Downie P; Williams B; Rosenbluh J; Gough D; Cain JE; Firestein R, 2023, 'SYST-15 GENERATION AND MULTI-DIMENSIONAL PROFILING OF A CHILDHOOD CANCER CELL LINE ATLAS DEFINES NEW THERAPEUTIC OPPORTUNITIES', Neuro-Oncology Advances, 5, pp. iii30 - iii30, http://dx.doi.org/10.1093/noajnl/vdad070.119
    Journal articles | 2023
    Ehteda A; Khan A; Rajakumar G; Vanniasinghe AS; Gopalakrishnan A; Liu J; Tsoli M; Ziegler DS, 2023, 'Microtubule-targeting combined with HDAC inhibition is a novel therapeutic strategy for Diffuse Intrinsic Pontine Gliomas.', Mol Cancer Ther, http://dx.doi.org/10.1158/1535-7163.MCT-23-0179
    Journal articles | 2023
    Geoerger B; Marshall LV; Nysom K; Makin G; Bouffet E; Defachelles AS; Amoroso L; Aerts I; Leblond P; Barahona P; Van-Vlerken K; Fu E; Solca F; Lorence RM; Ziegler DS, 2023, 'Afatinib in paediatric patients with recurrent/refractory ErbB-dysregulated tumours: Results of a phase I/expansion trial', European Journal of Cancer, 188, pp. 8 - 19, http://dx.doi.org/10.1016/j.ejca.2023.04.007
    Journal articles | 2023
    Gereis JM; Hetherington K; Robertson EG; Daly R; Donoghoe MW; Ziegler DS; Marshall GM; Lau LMS; Marron JM; Wakefield CE, 2023, 'Parents’ and adolescents’ perspectives and understanding of information about childhood cancer precision medicine', Cancer, http://dx.doi.org/10.1002/cncr.34914
    Journal articles | 2023
    Gonzales-Aloy E; Ahmed-Cox A; Tsoli M; Ziegler DS; Kavallaris M, 2023, 'From cells to organoids: The evolution of blood-brain barrier technology for modelling drug delivery in brain cancer', Advanced Drug Delivery Reviews, 196, pp. 114777, http://dx.doi.org/10.1016/j.addr.2023.114777
    Journal articles | 2023
    Hardin EC; Schmid S; Sommerkamp A; Bodden C; Heipertz A-E; Sievers P; Wittmann A; Milde T; Pfister SM; von Deimling A; Horn S; Herz NA; Simon M; Perera AA; Azizi A; Cruz O; Curry S; Van Damme A; Garami M; Hargrave D; Kattamis A; Kotnik BF; Lähteenmäki P; Scheinemann K; Schouten-van Meeteren AYN; Sehested A; Viscardi E; Wormdal OM; Zapotocky M; Ziegler DS; Koch A; Driever PH; Witt O; Capper D; Sahm F; Jones DTW; van Tilburg CM, 2023, 'LOGGIC Core BioClinical Data Bank: Added clinical value of RNA-Seq in an international molecular diagnostic registry for pediatric low-grade glioma patients.', Neuro Oncol, http://dx.doi.org/10.1093/neuonc/noad078
    Journal articles | 2023
    Hayden E; Franshaw L; Upton D; Liu J; Nguyen H; Joshi S; Tsoli M; Dolman E; Rayner B; Ziegler D, 2023, 'Abstract 1561: Preclinical examination of PLK1 inhibitors for the treatment of diffuse midline gliomas', Cancer Research, 83, pp. 1561 - 1561, http://dx.doi.org/10.1158/1538-7445.am2023-1561
    Journal articles | 2023
    Kilburn L; Khuong-Quang D-A; Nysom K; Landi D; Ziegler D; Driever PH; Leary S; Bailey S; Van der Lugt J; Perreault S; Waanders A; Baxter P; Witt O; Hargrave D; McCowage G; Zhao X; Da Costa D; Cox M; Manley P; Hansford J, 2023, 'LGG-09. CLINICAL ACTIVITY OF PAN-RAF INHIBITOR TOVORAFENIB IN THE REGISTRATIONAL PEDIATRIC LOW-GRADE GLIOMA ARM OF THE PHASE 2 FIREFLY-1 (PNOC026) STUDY', Neuro-Oncology, 25, pp. i57 - i57, http://dx.doi.org/10.1093/neuonc/noad073.219
    Journal articles | 2023
    Kilburn LB; Khuong-Quang D-A; Nysom K; Landi DB; Ziegler DS; Hernáiz Driever P; Leary S; Bailey S; van der Lugt J; Perreault S; Waanders AJ; Baxter PA; Witt O; Hargrave DR; McCowage GB; Zhao X; Da Costa D; Cox MC; Manley P; Hansford J, 2023, 'Clinical activity of pan-RAF inhibitor tovorafenib in the registrational pediatric low-grade glioma arm of the phase 2 FIREFLY-1 (PNOC026) study.', Journal of Clinical Oncology, 41, pp. 10004 - 10004, http://dx.doi.org/10.1200/jco.2023.41.16_suppl.10004
    Journal articles | 2023
    Lilly JV; Rokita JL; Mason JL; Patton T; Stefankiewiz S; Higgins D; Trooskin G; Larouci CA; Arya K; Appert E; Heath AP; Zhu Y; Brown MA; Zhang B; Farrow BK; Robins S; Morgan AM; Nguyen TQ; Frenkel E; Lehmann K; Drake E; Sullivan C; Plisiewicz A; Coleman N; Patterson L; Koptyra M; Helili Z; Van Kuren N; Young N; Kim MC; Friedman C; Lubneuski A; Blackden C; Williams M; Baubet V; Tauhid L; Galanaugh J; Boucher K; Ijaz H; Cole KA; Choudhari N; Santi M; Moulder RW; Waller J; Rife W; Diskin SJ; Mateos M; Parsons DW; Pollack IF; Goldman S; Leary S; Caporalini C; Buccoliero AM; Scagnet M; Haussler D; Hanson D; Firestein R; Cain J; Phillips JJ; Gupta N; Mueller S; Grant G; Monje-Deisseroth M; Partap S; Greenfield JP; Hashizume R; Smith A; Zhu S; Johnston JM; Fangusaro JR; Miller M; Wood MD; Gardner S; Carter CL; Prolo LM; Pisapia J; Pehlivan K; Franson A; Niazi T; Rubin J; Abdelbaki M; Ziegler DS; Lindsay HB; Stucklin AG; Gerber N; Vaske OM; Quinsey C; Rood BR; Nazarian J; Raabe E; Jackson EM; Stapleton S; Lober RM; Kram DE; Koschmann C; Storm PB; Lulla RR; Prados M; Resnick AC; Waanders AJ, 2023, 'The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science', Neoplasia (United States), 35, pp. 100846, http://dx.doi.org/10.1016/j.neo.2022.100846
    Journal articles | 2023
    Mayoh C; Gifford AJ; Terry R; Lau LMS; Wong M; Rao P; Shai-Hee T; Saletta F; Khuong-Quang DA; Qin V; Mateos MK; Meyran D; Miller KE; Yuksel A; Mould EVA; Bowen-James R; Govender D; Senapati A; Zhukova N; Omer N; Dholaria H; Alvaro F; Tapp H; Diamond Y; Pozza LD; Moore AS; Nicholls W; Gottardo NG; McCowage G; Hansford JR; Khaw SL; Wood PJ; Catchpoole D; Cottrell CE; Mardis ER; Marshall GM; Tyrrell V; Haber M; Ziegler DS; Vittorio O; Trapani JA; Cowley MJ; Neeson PJ; Ekert PG, 2023, 'A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer', Genome Medicine, 15, http://dx.doi.org/10.1186/s13073-023-01170-x
    Journal articles | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow SO; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, 'High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer', Cancer research, 83, pp. 2716 - 2732, http://dx.doi.org/10.1158/0008-5472.CAN-22-3702
    Journal articles | 2023
    McGill BC; Wakefield CE; Tucker KM; Daly RA; Donoghoe MW; Vetsch J; Warby M; Fuentes-Bolanos NA; Barlow-Stewart K; Kirk J; Courtney E; O’Brien TA; Marshall GM; Pinese M; Cowley MJ; Tyrrell V; Deyell RJ; Ziegler DS; Hetherington K, 2023, 'Parents’ expectations, preferences, and recall of germline findings in a childhood cancer precision medicine trial', Cancer, http://dx.doi.org/10.1002/cncr.34917
    Journal articles | 2023
    Poursani EM; Mercatelli D; Raninga P; Bell JL; Saletta F; Kohane FV; Neumann DP; Zheng Y; Rouaen JRC; Jue TR; Michniewicz FT; Schadel P; Kasiou E; Tsoli M; Cirillo G; Waters S; Shai-Hee T; Cazzoli R; Brettle M; Slapetova I; Kasherman M; Whan R; Souza-Fonseca-Guimaraes F; Vahdat L; Ziegler D; Lock JG; Giorgi FM; Khanna KK; Vittorio O, 2023, 'Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer', Cell and Bioscience, 13, http://dx.doi.org/10.1186/s13578-023-01083-7
    Journal articles | 2023
    Staunton J; Robertson PA; Harris A; Mayoh C; Wong M; Rumford M; Fuentes-Bolanos N; Cowley M; Lau L; Ziegler DS; Barahona P; Manoharan N, 2023, 'HGG-20. NOVEL PAEDIATRIC CASE OF A SPINAL HIGH-GRADE ASTROCYTOMA WITH PILOID FEATURES IN A PATIENT WITH NOONAN SYNDROME', Neuro-Oncology, 25, pp. i44 - i44, http://dx.doi.org/10.1093/neuonc/noad073.169
    Journal articles | 2023
    Sun CX; Daniel P; Bradshaw G; Shi H; Loi M; Chew N; Parackal S; Tsui V; Liang Y; Koptyra M; Adjumain S; Sun C; Chong WC; Fernando D; Drinkwater C; Tourchi M; Habarakada D; Sooraj D; Carvalho D; Storm PB; Baubet V; Sayles LC; Fernandez E; Nguyen T; Pörksen M; Doan A; Crombie DE; Panday M; Zhukova N; Dun MD; Ludlow LE; Day B; Stringer BW; Neeman N; Rubens JA; Raabe EH; Vinci M; Tyrrell V; Fletcher JI; Ekert PG; Dumevska B; Ziegler DS; Tsoli M; Syed Sulaiman NF; Loh AHP; Low SYY; Sweet-Cordero EA; Monje M; Resnick A; Jones C; Downie P; Williams B; Rosenbluh J; Gough D; Cain JE; Firestein R, 2023, 'Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities', Cancer Cell, 41, pp. 660 - 677.e7, http://dx.doi.org/10.1016/j.ccell.2023.03.007
    Journal articles | 2023
    Trinder SM; McKay C; Power P; Topp M; Chan B; Valvi S; McCowage G; Govender D; Kirby M; Ziegler DS; Manoharan N; Hassall T; Kellie S; Heath J; Alvaro F; Wood P; Laughton S; Tsui K; Dodgshun A; Eisenstat DD; Endersby R; Luen SJ; Koh ES; Sim HW; Kong B; Gottardo NG; Whittle JR; Khuong-Quang DA; Hansford JR, 2023, 'BRAF-mediated brain tumors in adults and children: A review and the Australian and New Zealand experience', Frontiers in Oncology, 13, pp. 1154246, http://dx.doi.org/10.3389/fonc.2023.1154246
    Journal articles | 2023
    White CL; Kinross KM; Buntine MK; Rasouli E; Strong R; Jones JM; Cain JE; Sturm D; Sahm F; Jones DTW; Pfister SM; Robertson T; D'Arcy C; Rodriguez ML; Dyke JM; Junckerstorff R; Bhuva DD; Davis MJ; Wood P; Hassall T; Ziegler DS; Kellie S; McCowage G; Alvaro F; Kirby M; Heath JA; Tsui K; Dodgshun A; Eisenstat DD; Khuong-Quang D-A; Wall M; Algar EM; Gottardo NG; Hansford JR, 2023, 'Implementation of DNA Methylation Array Profiling in Pediatric Central Nervous System Tumors: The AIM BRAIN Project: An Australian and New Zealand Children's Hematology and Oncology Group Study.', J Mol Diagn, http://dx.doi.org/10.1016/j.jmoldx.2023.06.013
    Journal articles | 2023
    Whitehouse JP; Hii H; Mayoh C; Wong M; Ajuyah P; Barahona P; Cui L; Dholaria H; White CL; Buntine MK; Byrne J; Rodrigues da Silva K; Howlett M; Girard EJ; Tsoli M; Ziegler DS; Dyke JM; Lee S; Ekert PG; Cowley MJ; Gottardo NG; Endersby R, 2023, 'In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma', Frontiers in Oncology, 13, pp. 1123492, http://dx.doi.org/10.3389/fonc.2023.1123492
    Journal articles | 2023
    van Tilburg CM; Kilburn LB; Crotty E; Smith AA; Perreault S; Franson AF; Jabado N; Hoffman LM; Schmidt R; Schouten-van Meeteren AYN; Sehestedt A; Opocher E; Hernáiz Driever P; Avula S; Ziegler DS; Qiu J; Tsao L-P; Manley P; Hargrave DR; Witt O, 2023, 'LOGGIC/FIREFLY-2: A phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration.', Journal of Clinical Oncology, 41, pp. TPS10067 - TPS10067, http://dx.doi.org/10.1200/jco.2023.41.16_suppl.tps10067
    Journal articles | 2022
    Bartlett AL; Lane A; Chaney B; Escorza NY; Black K; Cochrane A; Minturn J; Bartels U; Warren K; Hansford J; Ziegler D; Diez B; Goldman S; Packer R; Kieran M; DeWire-Schottmiller M; Erker C; Monje-Deisseroth M; Wagner L; Koschmann C; Dorris K; Shih CS; Hassall T; Samson Y; Fisher P; Wang SS; Tsui K; Sevlever G; Zhu X; Dexheimer P; Asher A; Fuller C; Drissi R; Jones B; Leach J; Fouladi M, 2022, 'Characteristics of children ≤36 months of age with DIPG: A report from the international DIPG registry', Neuro-Oncology, 24, pp. 2190 - 2199, http://dx.doi.org/10.1093/neuonc/noac123
    Journal articles | 2022
    Burke MJ; Ziegler DS; Bautista F; Attarbaschi A; Gore L; Locatelli F; M. O'Brien M; Pauly M; Kormany WN; Tian S; Morris CL; Baruchel A, 2022, 'Phase 1b study of carfilzomib with induction chemotherapy in pediatric relapsed/refractory acute lymphoblastic leukemia', Pediatric Blood and Cancer, 69, http://dx.doi.org/10.1002/pbc.29999
    Journal articles | 2022
    Das A; Sudhaman S; Morgenstern D; Coblentz A; Chung J; Stone SC; Alsafwani N; Liu ZA; Karsaneh OAA; Soleimani S; Ladany H; Chen D; Zatzman M; Cabric V; Nobre L; Bianchi V; Edwards M; Sambira Nahum LC; Ercan AB; Nabbi A; Constantini S; Dvir R; Yalon-Oren M; Campino GA; Caspi S; Larouche V; Reddy A; Osborn M; Mason G; Lindhorst S; Bronsema A; Magimairajan V; Opocher E; De Mola RL; Sabel M; Frojd C; Sumerauer D; Samuel D; Cole K; Chiaravalli S; Massimino M; Tomboc P; Ziegler DS; George B; Van Damme A; Hijiya N; Gass D; McGee RB; Mordechai O; Bowers DC; Laetsch TW; Lossos A; Blumenthal DT; Sarosiek T; Yen LY; Knipstein J; Bendel A; Hoffman LM; Luna-Fineman S; Zimmermann S; Scheers I; Nichols KE; Zapotocky M; Hansford JR; Maris JM; Dirks P; Taylor MD; Kulkarni AV; Shroff M; Tsang DS; Villani A; Xu W; Aronson M; Durno C; Shlien A; Malkin D; Getz G; Maruvka YE; Ohashi PS; Hawkins C; Pugh TJ; Bouffet E; Tabori U, 2022, 'Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency', Nature Medicine, 28, pp. 125 - 135, http://dx.doi.org/10.1038/s41591-021-01581-6
    Journal articles | 2022
    Doz F; Van Tilburg CM; Geoerger B; Højgaard M; Øra I; Boni V; Capra M; Chisholm J; Chung HC; Dubois SG; Gallego-Melcon S; Gerber NU; Goto H; Grilley-Olson JE; Hansford JR; Hong DS; Italiano A; Kang HJ; Nysom K; Thorwarth A; Stefanowicz J; Tahara M; Ziegler DS; Gavrilovic IT; Norenberg R; Dima L; De La Cuesta E; Laetsch TW; Drilon A; Perreault S, 2022, 'Efficacy and safety of larotrectinib in TRK fusion-positive primary central nervous system tumors', Neuro-Oncology, 24, pp. 997 - 1007, http://dx.doi.org/10.1093/neuonc/noab274
    Journal articles | 2022
    Erker C; Lane A; Chaney B; Leary S; Minturn JE; Bartels U; Packer RJ; Dorris K; Gottardo NG; Warren KE; Broniscer A; Kieran MW; Zhu X; White P; Dexheimer PJ; Black K; Asher A; Dewire M; Hansford JR; Gururangan S; Nazarian J; Ziegler DS; Sandler E; Bartlett A; Goldman S; Shih CS; Hassall T; Dholaria H; Bandopadhayay P; Samson Y; Monje M; Fisher PG; Dodgshun A; Parkin S; Chintagumpala M; Tsui K; Gass D; Larouche V; Broxson E; Garcia Lombardi M; Wang SS; Ma J; Hawkins C; Hamideh D; Wagner L; Koschmann C; Fuller C; Drissi R; Jones BV; Leach J; Fouladi M, 2022, 'Characteristics of patients ≥10 years of age with diffuse intrinsic pontine glioma: a report from the International DIPG/DMG Registry', Neuro-Oncology, 24, pp. 141 - 152, http://dx.doi.org/10.1093/neuonc/noab140
    Journal articles | 2022
    Gargett T; Ebert LM; Truong NTH; Kollis PM; Sedivakova K; Yu W; Yeo ECF; Wittwer NL; Gliddon BL; Tea MN; Ormsby R; Poonnoose S; Nowicki J; Vittorio O; Ziegler DS; Pitson SM; Brown MP, 2022, 'GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma', Journal for ImmunoTherapy of Cancer, 10, pp. e005187, http://dx.doi.org/10.1136/jitc-2022-005187
    Journal articles | 2022
    Gereis J; Hetherington K; Ha L; Robertson EG; Ziegler DS; Barlow-Stewart K; Tucker KM; Marron JM; Wakefield CE, 2022, 'Parents’ understanding of genome and exome sequencing for pediatric health conditions: a systematic review', European Journal of Human Genetics, 30, pp. 1216 - 1225, http://dx.doi.org/10.1038/s41431-022-01170-2
    Journal articles | 2022
    Hetherington K; Wakefield CE; Kunalan KPK; Donoghoe MW; McGill BC; Fardell JE; Daly R; Deyell RJ; Ziegler DS, 2022, 'Quality of Life (QoL) of Children and Adolescents Participating in a Precision Medicine Trial for High-Risk Childhood Cancer', Cancers, 14, pp. 5310 - 5310, http://dx.doi.org/10.3390/cancers14215310
    Journal articles | 2022
    Hunter JD; Robertson EG; Hetherington K; Ziegler DS; Marshall GM; Kirk J; Marron JM; Denburg AE; Barlow-Stewart K; Warby M; Tucker KM; Lee BM; O’Brien TA; Wakefield CE, 2022, 'What’s in a Name? Parents’ and Healthcare Professionals’ Preferred Terminology for Pathogenic Variants in Childhood Cancer Predisposition Genes', Journal of Personalized Medicine, 12, http://dx.doi.org/10.3390/jpm12081327
    Journal articles | 2022
    Kong BY; Carter C; Nowak AK; Hovey E; Lwin Z; Haghighi N; Gan HK; Sim HW; Ziegler DS; Barton K; Parkinson J; Leonard R; Khasraw M; Foote M, 2022, 'Barriers and potential solutions to international collaboration in neuro-oncology clinical trials: Challenges from the Australian perspective', Asia-Pacific Journal of Clinical Oncology, 18, pp. 259 - 266, http://dx.doi.org/10.1111/ajco.13606
    Journal articles | 2022
    Lau LMS; Mayoh C; Xie J; Barahona P; MacKenzie KL; Wong M; Kamili A; Tsoli M; Failes TW; Kumar A; Mould EVA; Gifford A; Chow SO; Pinese M; Fletcher JI; Arndt GM; Khuong-Quang DA; Wadham C; Batey D; Eden G; Trebilcock P; Joshi S; Alfred S; Gopalakrishnan A; Khan A; Grebert Wade D; Strong PA; Manouvrier E; Morgan LT; Span M; Lim JY; Cadiz R; Ung C; Thomas DM; Tucker KM; Warby M; McCowage GB; Dalla-Pozza L; Byrne JA; Saletta F; Fellowes A; Fox SB; Norris MD; Tyrrell V; Trahair TN; Lock RB; Cowley MJ; Ekert PG; Haber M; Ziegler DS; Marshall GM, 2022, 'In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer', EMBO Molecular Medicine, 14, http://dx.doi.org/10.15252/emmm.202114608
    Journal articles | 2022
    Lazow MA; Fuller C; Dewire M; Lane A; Bandopadhayay P; Bartels U; Bouffet E; Cheng S; Cohen KJ; Cooney TM; Coven SL; Dholaria H; Diez B; Dorris K; El-Ayadi M; El-Sheikh A; Fisher PG; Fonseca A; Garcia Lombardi M; Greiner RJ; Goldman S; Gottardo N; Gururangan S; Hansford JR; Hassall T; Hawkins C; Kilburn L; Koschmann C; Leary SE; Ma J; Minturn JE; Monje-Deisseroth M; Packer R; Samson Y; Sandler ES; Sevlever G; Tinkle CL; Tsui K; Wagner LM; Zaghloul M; Ziegler DS; Chaney B; Black K; Asher A; Drissi R; Fouladi M; Jones BV; Leach JL, 2022, 'Accuracy of central neuro-imaging review of DIPG compared with histopathology in the International DIPG Registry', Neuro-Oncology, 24, pp. 821 - 833, http://dx.doi.org/10.1093/neuonc/noab245
    Journal articles | 2022
    Lazow MA; Nievelstein MT; Lane A; Bandopadhayhay P; DeWire-Schottmiller M; Fouladi M; Glod JW; Greiner RJ; Hoffman LM; Hummel TR; Kilburn L; Leary S; Minturn JE; Packer R; Ziegler DS; Chaney B; Black K; de Blank P; Leach JL, 2022, 'Volumetric endpoints in diffuse intrinsic pontine glioma: p correlations in the International DIPG/DMG Registry', Neuro-Oncology, 24, pp. 1598 - 1608, http://dx.doi.org/10.1093/neuonc/noac037
    Journal articles | 2022
    Lehmann R; Rayner BS; Ziegler DS, 2022, 'Resistance mechanisms in BRAFV600E paediatric high-grade glioma and current therapeutic approaches', Frontiers in Oncology, 12, http://dx.doi.org/10.3389/fonc.2022.1031378
    Journal articles | 2022
    Pommert L; Schafer ES; Malvar J; Gossai N; Florendo E; Pulakanti K; Heimbruch K; Stelloh C; Chi YY; Sposto R; Rao S; Huynh VT; Brown P; Chang BH; Colace SI; Hermiston ML; Heym K; Hutchinson RJ; Kaplan JA; Mody R; O'Brien TA; Place AE; Shaw PH; Ziegler DS; Wayne A; Bhojwani D; Burke MJ, 2022, 'Decitabine and vorinostat with FLAG chemotherapy in pediatric relapsed/refractory AML: Report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium', American Journal of Hematology, 97, pp. 613 - 622, http://dx.doi.org/10.1002/ajh.26510
    Journal articles | 2022
    Tsai JW; Cejas P; Wang DK; Patel S; Wu DW; Arounleut P; Wei X; Zhou N; Syamala S; Dubois FPB; Crane A; Pelton K; Vogelzang J; Sousa C; Baguette A; Chen X; Condurat AL; Dixon-Clarke SE; Zhou KN; Lu SD; Gonzalez EM; Chacon MS; Digiacomo JJ; Kumbhani R; Novikov D; Hunter J; Tsoli M; Ziegler DS; Dirksen U; Jager N; Balasubramanian GP; Kramm CM; Nathrath M; Bielack S; Baker SJ; Zhang J; McFarland JM; Getz G; Aguet F; Jabado N; Witt O; Pfister SM; Ligon KL; Hovestadt V; Kleinman CL; Long H; Jones DTW; Bandopadhayay P; Phoenix TN, 2022, 'FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits', Cancer Research, 82, pp. 2980 - 3001, http://dx.doi.org/10.1158/0008-5472.CAN-22-0671
    Journal articles | 2022
    Upton DH; Ung C; George SM; Tsoli M; Kavallaris M; Ziegler DS, 2022, 'Challenges and opportunities to penetrate the blood-brain barrier for brain cancer therapy', Theranostics, 12, pp. 4734 - 4752, http://dx.doi.org/10.7150/THNO.69682
    Journal articles | 2022
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    Goto H; Geoerger B; DuBois SG; Grilley-Olson JE; van Tilburg CM; Schulte J; Kang HJ; Tahara M; Boni V; Perreault S; Capra M; Reeves JA; Brega N; Childs BH; Laetsch TW; Ziegler DS; Doz F, 2020, 'EPCT-08. ACTIVITY OF LAROTRECTINIB IN PEDIATRIC TROPOMYOSIN RECEPTOR KINASE (TRK) FUSION CANCER PATIENTS WITH PRIMARY CENTRAL NERVOUS SYSTEM (CNS) TUMORS', Neuro-Oncology, 22, pp. iii305 - iii305, http://dx.doi.org/10.1093/neuonc/noaa222.132
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    Hanson D; Hoffman LM; Nagabushan S; Goumnerova LC; Rathmann A; Vogel T; Ziegler DS; Chi S, 2020, 'A modified IRS-III chemotherapy regimen leads to prolonged survival in children with embryonal tumor with multilayer rosettes', Neuro-Oncology Advances, 2, pp. vdaa120, http://dx.doi.org/10.1093/noajnl/vdaa120
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    McGill BC; Wakefield CE; Hetherington K; Munro LJ; Warby M; Lau L; Tyrrell V; Ziegler DS; O’brien TA; Marshall GM; Malkin D; Hansford JR; Tucker KM; Vetsch J, 2020, '“Balancing Expectations with Actual Realities”: Conversations with Clinicians and Scientists in the First Year of a High-Risk Childhood Cancer Precision Medicine Trial', Journal of Personalized Medicine, 10, http://dx.doi.org/10.3390/jpm10010009
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    Michniewicz F; Saletta F; Rouen J; Ziegler D; Vittorio O, 2020, 'DIPG-83. USING COPPER CHELATING AGENTS TO TARGET RECEPTOR TYROSINE KINASE SIGNALLING IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', Neuro-Oncology, 22, pp. iii303 - iii303, http://dx.doi.org/10.1093/neuonc/noaa222.124
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    Schulte JH; Moreno L; Ziegler DS; Marshall LV; Zwaan CM; Irwin M; Casanova M; Sabado C; Wulff B; Stegert M; Wang L; Hurtado FK; Branle F; Fischer M; Geoerger B, 2020, 'Final analysis of phase I study of ceritinib in pediatric patients with malignancies harboring activated anaplastic lymphoma kinase (ALK).', Journal of Clinical Oncology, 38, pp. 10505 - 10505, http://dx.doi.org/10.1200/jco.2020.38.15_suppl.10505
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    Shen H; Yu M; Tsoli M; Chang C; Joshi S; Liu J; Ryall S; Chornenkyy Y; Siddaway R; Hawkins C; Ziegler DS, 2020, 'Targeting reduced mitochondrial DNA quantity as a therapeutic approach in pediatric high-grade gliomas', Neuro-Oncology, 22, pp. 139 - 151, http://dx.doi.org/10.1093/neuonc/noz140
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    Terry RL; Meyran D; Ziegler DS; Haber M; Ekert PG; Trapani JA; Neeson PJ, 2020, 'Immune profiling of pediatric solid tumors', Journal of Clinical Investigation, 130, pp. 3391 - 3402, http://dx.doi.org/10.1172/JCI137181
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    Vetsch J; Hetherington K; Wakefield C; Ziegler D, 2020, 'Families’ experiences of a precision medicine trial for childhood cancer', Oncology Central
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    Wood P; Desai J; Waldeck K; Cain J; Gottardo N; Strong R; Kinross K; Carr M; Jones J; Wong L; Ziegler D; Hansford J; Michael M; Ashley D, 2020, 'ATRT-08. A PHASE II STUDY OF CONTINUOUS LOW DOSE PANOBINOSTAT IN PAEDIATRIC PATIENTS WITH MALIGNANT RHABDOID TUMORS/ATYPICAL TERATOID RHABDOID TUMORS', Neuro-Oncology, 22, pp. iii277 - iii277, http://dx.doi.org/10.1093/neuonc/noaa222.008
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    Burke MJ; Ziegler DS; Bautista Sirvent FJ; Attarbaschi A; Gore L; Locatelli F; O'Brien MM; Pauly M; Obreja M; Morris CL; Baruchel A, 2019, 'Phase 1b Study of Carfilzomib in Combination with Induction Chemotherapy in Children with Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL)', Blood, 134, pp. 3873 - 3873, http://dx.doi.org/10.1182/blood-2019-127350
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    Doz F; Geoerger B; DuBois SG; Grilley-Olson JE; van Tilburg CM; Italiano A; Lissat A; Jin Kang H; Tahara M; Boni V; Perreault S; Capra M; Nanda S; Brega N; Holynskyj A; Ziegler DS; Hong DS; Hyman DM; Drilon A, 2019, 'RARE-45. ACTIVITY OF LAROTRECTINIB IN TRK FUSION CANCER PATIENTS WITH PRIMARY CENTRAL NERVOUS SYSTEM TUMORS', Neuro-Oncology, 21, pp. vi231 - vi231, http://dx.doi.org/10.1093/neuonc/noz175.968
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    Drilon AE; DuBois SG; Farago AF; Geoerger B; Grilley-Olson JE; Hong DS; Sohal D; van Tilburg CM; Ziegler DS; Ku N; Cox MC; Nanda S; Childs BH; Doz FP, 2019, 'Activity of larotrectinib in TRK fusion cancer patients with brain metastases or primary central nervous system tumors.', Journal of Clinical Oncology, 37, pp. 2006 - 2006, http://dx.doi.org/10.1200/jco.2019.37.15_suppl.2006
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    Franshaw L; Tsoli M; Lau LMS; Ziegler DS, 2019, 'Translating palbociclib to the clinic for DIPG - What is truly achievable?', EBioMedicine, 45, pp. 22, http://dx.doi.org/10.1016/j.ebiom.2019.06.024
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    Hanson D; Chi S; Ziegler D, 2019, 'MEDU-38. A CASE SERIES OF CHILDREN WITH EMBRYONAL TUMOR WITH MULTILAYER ROSETTES TREATED WITH A MODIFIED IRS-III CHEMOTHERAPY BACKBONE', Neuro-Oncology, 21, pp. ii111 - ii111, http://dx.doi.org/10.1093/neuonc/noz036.196
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    Vetsch J; Wakefield CE; Techakesari P; Warby M; Ziegler DS; O'Brien TA; Drinkwater C; Neeman N; Tucker K, 2019, 'Healthcare professionals’ attitudes toward cancer precision medicine: A systematic review', Seminars in Oncology, 46, pp. 291 - 303, http://dx.doi.org/10.1053/j.seminoncol.2019.05.001
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    Dixon F; Ziegler DS; Bajuk B; Wright I; Hilder L; Abdel Latif ME; Somanathan A; Oei JL, 2018, 'Treatment with nitric oxide in the neonatal intensive care unit is associated with increased risk of childhood cancer', Acta Paediatrica, International Journal of Paediatrics, 107, pp. 2092 - 2098, http://dx.doi.org/10.1111/apa.14436
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    Fletcher JI; Ziegler DS; Trahair TN; Marshall GM; Haber M; Norris MD, 2018, 'Too many targets, not enough patients: Rethinking neuroblastoma clinical trials', Nature Reviews Cancer, 18, pp. 389 - 400, http://dx.doi.org/10.1038/s41568-018-0003-x
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    Kabalan P; Gifford AJ; Ziegler DS, 2018, 'Unresectable VIP-secreting neuroblastoma: Efficacy of debulking and steroids for symptom control', Pediatric Blood and Cancer, 65, http://dx.doi.org/10.1002/pbc.27358
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    Li BK; Vasiljevic A; Ho B; Jouvet A; Hwang EI; Hansford JR; Laquerriere A; Delisle M-B; Gururangan S; Fangusaro JR; Forest F; Sumihito N; Toledano H; Fouladi M; Gauchotte G; Ziegler DS; Bouffet E; Grundy RG; Dufour C; Huang AA, 2018, 'Genomic landscape of pineoblastoma.', Journal of Clinical Oncology, 36, pp. 2028 - 2028, http://dx.doi.org/10.1200/jco.2018.36.15_suppl.2028
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    Marachelian A; Hogarty MD; Flynn A; Liu K; Gerner EW; Bruckheimer E; Shamirian A; Hasenauer C; Norris M; Haber M; Groshen SG; Ziegler DS; Matthay KK, 2018, 'NANT 2012-01: Phase 1 study of DFMO and celecoxib with cyclophosphamide and topotecan for relapsed or refractory high-risk neuroblastoma.', JOURNAL OF CLINICAL ONCOLOGY, 36, http://dx.doi.org/10.1200/JCO.2018.36.15_suppl.10558
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    Robertson EG; Wakefield CE; Cohn RJ; O'Brien T; Ziegler DS; Fardell JE, 2018, 'The development of delta: Using agile to develop a decision aid for pediatric oncology clinical trial enrollment', JMIR Research Protocols, 7, http://dx.doi.org/10.2196/resprot.9258
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    Sagnella SM; Trieu J; Brahmbhatt H; MacDiarmid JA; MacMillan A; Whan RM; Fife CM; McCarroll JA; Gifford AJ; Ziegler DS; Kavallaris M, 2018, 'Targeted doxorubicin-loaded bacterially derived nano-cells for the treatment of neuroblastoma', Molecular Cancer Therapeutics, 17, pp. 1012 - 1023, http://dx.doi.org/10.1158/1535-7163.MCT-17-0738
    Journal articles | 2018
    Sun W; Malvar J; Sposto R; Verma A; Wilkes JJ; Dennis R; Heym K; Laetsch TW; Widener M; Rheingold SR; Oesterheld J; Hijiya N; Sulis ML; Huynh V; Place AE; Bittencourt H; Hutchinson R; Messinger Y; Chang B; Matloub Y; Ziegler DS; Gardner R; Cooper T; Ceppi F; Hermiston M; Dalla-Pozza L; Schultz KR; Gaynon P; Wayne AS; Whitlock JA, 2018, 'Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study', Leukemia, 32, pp. 2316 - 2325, http://dx.doi.org/10.1038/s41375-018-0094-0
    Journal articles | 2018
    Tsoli M; Liu J; Franshaw L; Shen H; Cheng C; Jung MS; Joshi S; Ehteda A; Khan A; Montero-Carcabosso A; Dilda PJ; Hogg P; Ziegler DS, 2018, 'Dual targeting of mitochondrial function and mTOR pathway as a therapeutic strategy for diffuse intrinsic pontine glioma', Oncotarget, 9, pp. 7541 - 7556, http://dx.doi.org/10.18632/oncotarget.24045
    Journal articles | 2018
    Tsoli M; Wadham C; Pinese M; Failes T; Joshi S; Mould E; Yin JX; Gayevskiy V; Kumar A; Kaplan W; Ekert PG; Saletta F; Franshaw L; Liu J; Gifford A; Weber MA; Rodriguez M; Cohn RJ; Arndt G; Tyrrell V; Haber M; Trahair T; Marshall GM; McDonald K; Cowley MJ; Ziegler DS, 2018, 'Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer', Cancer Biology and Therapy, 19, pp. 1078 - 1087, http://dx.doi.org/10.1080/15384047.2018.1491498
    Journal articles | 2018
    Vedi A; Mitchell R; Shanmuganathan S; Oswald C; Marshall GM; Trahair T; Sivarajasingam S; Ziegler DS, 2018, 'Increased Survival for Children with Acute Myeloid Leukemia Results from Improved Postrelapse Treatment', Journal of Pediatric Hematology/Oncology, 40, pp. 541 - 547, http://dx.doi.org/10.1097/MPH.0000000000001215
    Journal articles | 2018
    Ziegler DS; Wong M; Mayoh C; Kumar A; Tsoli M; Mould E; Tyrrell V; Khuong-Quang DA; Pinese M; Gayevskiy V; Cohn RJ; Lau LMS; Reynolds M; Cox MC; Gifford A; Rodriguez M; Cowley MJ; Ekert PG; Marshall GM; Haber M, 2018, 'Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma', British Journal of Cancer, 119, pp. 693 - 696, http://dx.doi.org/10.1038/s41416-018-0251-2
    Journal articles | 2017
    Baugh J; Bartels U; Leach J; Jones B; Chaney B; Warren KE; Kirkendall J; Doughman R; Hawkins C; Miles L; Fuller C; Hassall T; Bouffet E; Lane A; Hargrave D; Grill J; Hoffman LM; Jones C; Towbin A; Savage SA; Monje M; Li XN; Ziegler DS; Veldhuijzen van Zanten S; Kramm CM; van Vuurden DG; Fouladi M, 2017, 'The international diffuse intrinsic pontine glioma registry: an infrastructure to accelerate collaborative research for an orphan disease', Journal of Neuro-Oncology, 132, pp. 323 - 331, http://dx.doi.org/10.1007/s11060-017-2372-5
    Journal articles | 2017
    Bhojwani D; Burke MJ; Horton T; Ziegler DS; Sulis ML; Schultz KR; Wayne A; Izraeli S; Chang BH, 2017, 'Investigating the biology of relapsed acute leukemia: Proceedings of the Therapeutic Advances for Childhood Leukemia & Lymphoma (TACL) Consortium Biology Working Group', Pediatric Hematology and Oncology, 34, pp. 355 - 364, http://dx.doi.org/10.1080/08880018.2017.1395937
    Journal articles | 2017
    Campbell BB; Angelini P; Fabrizio D; Elvin J; Light N; Bouffet E; Larouche V; Samuel D; Stearns D; Cole K; Opocher E; Thomas G; Sabel M; George B; Ziegler D; Lapierre N; Mason G; Magimajrajan V; Shlien A; Tabori U, 2017, 'IMMU-13. LARGE SCALE TUMOR MUTATIONAL BURDEN ANALYSIS OF PEDIATRIC TUMORS PROVIDES A DIAGNOSTIC TOOL FOR GERMLINE PREDISPOSITION AND REVEALS NOVEL CANDIDATES FOR IMMUNE CHECKPOINT INHIBITION', Neuro-Oncology, 19, pp. iv30 - iv30, http://dx.doi.org/10.1093/neuonc/nox083.123
    Journal articles | 2017
    Campbell BB; Angelini P; Light N; Bouffet E; Larouche V; Samuel D; Stearns D; Cole KA; Opocher E; Sabel M; George B; Ziegler D; Laperriere N; Meyn S; Malkin D; Shlien A; Tabori U, 2017, 'PDTM-21. LARGE SCALE TUMOR MUTATIONAL BURDEN ANALYSIS OF PEDIATRIC TUMORS PROVIDES A DIAGNOSTIC TOOL FOR GERMLINE PREDISPOSITION AND REVEALS NOVEL CANDIDATES FOR IMMUNE CHECKPOINT INHIBITION', Neuro-Oncology, 19, pp. vi194 - vi194, http://dx.doi.org/10.1093/neuonc/nox168.785
    Journal articles | 2017
    Campbell BB; Light N; Fabrizio D; Zatzman M; Fuligni F; de Borja R; Davidson S; Edwards M; Elvin JA; Hodel KP; Zahurancik WJ; Suo Z; Lipman T; Wimmer K; Kratz CP; Bowers DC; Laetsch TW; Dunn GP; Johanns TM; Grimmer MR; Smirnov IV; Larouche V; Samuel D; Bronsema A; Osborn M; Stearns D; Raman P; Cole KA; Storm PB; Yalon M; Opocher E; Mason G; Thomas GA; Sabel M; George B; Ziegler DS; Lindhorst S; Issai VM; Constantini S; Toledano H; Elhasid R; Farah R; Dvir R; Dirks P; Huang A; Galati MA; Chung J; Ramaswamy V; Irwin MS; Aronson M; Durno C; Taylor MD; Rechavi G; Maris JM; Bouffet E; Hawkins C; Costello JF; Meyn MS; Pursell ZF; Malkin D; Tabori U; Shlien A, 2017, 'Comprehensive Analysis of Hypermutation in Human Cancer', Cell, 171, pp. 1042 - 1056.e10, http://dx.doi.org/10.1016/j.cell.2017.09.048
    Journal articles | 2017
    Durno CA; Aronson M; Edwards M; Ling S; Larouche V; Bronsema A; Osborn M; Stearns D; Cole K; Oren M; Opocher E; Mason GE; Thomas G; Sabel M; George B; Ziegler D; Lindhorst S; Magimairajan V; Laperriere N; Samuel D; Bouffet E; Tabori U, 2017, 'Immune Check Point Inhibitor Treatment for Young Patients with Hypermutant Cancers', Gastroenterology, 152, pp. S141 - S141, http://dx.doi.org/10.1016/s0016-5085(17)30801-6
    Journal articles | 2017
    Hennika T; Hu G; Olaciregui NG; Barton KL; Ehteda A; Chitranjan A; Chang C; Gifford AJ; Tsoli M; Ziegler DS; Carcaboso AM; Becher OJ, 2017, 'Pre-clinical study of panobinostat in xenograft and genetically engineered murine diffuse intrinsic pontine glioma models', PLoS ONE, 12, http://dx.doi.org/10.1371/journal.pone.0169485
    Journal articles | 2017
    Lapin DH; Tsoli M; Ziegler DS, 2017, 'Genomic insights into diffuse intrinsic pontine glioma', Frontiers in Oncology, 7, http://dx.doi.org/10.3389/fonc.2017.00057
    Journal articles | 2017
    Sadras T; Heatley SL; Kok CH; McClure BJ; Yeung D; Hughes TP; Sutton R; Ziegler DS; White DL, 2017, 'A novel somatic JAK2 kinase-domain mutation in pediatric acute lymphoblastic leukemia with rapid on-treatment development of LOH', Cancer Genetics, 216-217, pp. 86 - 90, http://dx.doi.org/10.1016/j.cancergen.2017.07.008
    Journal articles | 2017
    Valvi S; Ziegler DS, 2017, 'Ganglioglioma arising from desmoplastic medulloblastoma: A case report and review of literature', Pediatrics, 139, http://dx.doi.org/10.1542/peds.2016-1403
    Journal articles | 2016
    Barbaro PM; Ziegler DS; Reddel RR, 2016, 'The wide-ranging clinical implications of the short telomere syndromes', Internal Medicine Journal, 46, pp. 393 - 403, http://dx.doi.org/10.1111/imj.12868
    Journal articles | 2016
    Davis T; Doyle H; Tobias V; Ellison DW; Ziegler DS, 2016, 'Case report of spontaneous resolution of a congenital glioblastoma', Pediatrics, 137, http://dx.doi.org/10.1542/peds.2015-1241
    Journal articles | 2016
    Evageliou NF; Haber M; Vu A; Laetsch TW; Murray J; Gamble LD; Cheng NC; Liu K; Reese M; Corrigan KA; Ziegler DS; Webber H; Hayes CS; Pawel B; Marshall GM; Zhao H; Gilmour SK; Norris MD; Hogarty MD, 2016, 'Polyamine antagonist therapies inhibit neuroblastoma initiation and progression', Clinical Cancer Research, 22, pp. 4391 - 4404, http://dx.doi.org/10.1158/1078-0432.CCR-15-2539
    Journal articles | 2016
    Franshaw L; Sivarajasingam S; Byrne J; Dalla-Pozza L; Marshall G; Norris M; Ziegler DS, 2016, 'Predictors of success of phase 2 paediatric oncology clinical trials', European Journal of Cancer, 69, pp. S63 - S64, http://dx.doi.org/10.1016/s0959-8049(16)32778-2
    Journal articles | 2016
    Liu PY; Sokolowski N; Guo ST; Siddiqi F; Atmadibrata B; Telfer TJ; Sun Y; Zhang L; Yu D; Mccarroll J; Liu B; Yang RH; Guo XY; Tee AE; Itoh K; Wang J; Kavallaris M; Haber M; Norris MD; Cheung BB; Byrne JA; Ziegler DS; Marshall GM; Dinger ME; Codd R; Zhang XD; Liu T, 2016, 'The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs', Oncotarget, 7, pp. 79217 - 79232, http://dx.doi.org/10.18632/oncotarget.12640
    Journal articles | 2015
    Carter DR; Murray J; Cheung BB; Gamble L; Koach J; Tsang J; Sutton S; Kalla H; Syed S; Gifford AJ; Issaeva N; Biktasova A; Atmadibrata B; Sun Y; Sokolowski N; Ling D; Kim PY; Webber H; Clark A; Ruhle M; Liu B; Oberthuer A; Fischer M; Byrne J; Saletta F; Thwe LM; Purmal A; Haderski G; Burkhart C; Speleman F; De Preter K; Beckers A; Ziegler DS; Liu T; Gurova KV; Gudkov AV; Norris MD; Haber M; Marshall GM, 2015, 'Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma', Science Translational Medicine, 7, http://dx.doi.org/10.1126/scitranslmed.aab1803
    Journal articles | 2015
    Ziegler DS, 2015, 'Never say never', Journal of Clinical Oncology, 33, pp. 518 - 520, http://dx.doi.org/10.1200/JCO.2014.58.7717
    Journal articles | 2014
    Saletta F; Wadham C; Byrne J; Ziegler D; McCowage G; Haber M; Marshal G; Norris M, 2014, 'Molecular profiling for factors predicting sensitivity or resistance to therapy in relapsed child cancer', EUROPEAN JOURNAL OF CANCER, 50, pp. 135 - 135, http://dx.doi.org/10.1016/S0959-8049(14)70547-7
    Journal articles | 2014
    Saletta F; Wadham C; Ziegler DS; Marshall GM; Haber M; McCowage G; Norris MD; Byrne JA, 2014, 'Molecular profiling of childhood cancer: Biomarkers and novel therapies', BBA Clinical, 1, pp. 59 - 77, http://dx.doi.org/10.1016/j.bbacli.2014.06.003
    Journal articles | 2014
    Vedi A; ziegler D, 2014, 'Antibody therapy for pediatric leukemia', Frontiers in Oncology, 4, pp. 1 - 10, http://dx.doi.org/10.3389/fonc.2014.00082
    Journal articles | 2014
    Whitlock J; dalla Pozza L; Goldberg JM; Silverman LB; Ziegler DS; Attarbaschi A; Brown P; Gardner RA; Gaynon PS; Hutchinson RJ; Marcus LJ; Messinger YH; Schultz KR; Vandergiessen J; Eckroth E; Locatelli F; Zwaan CM; Wood BL; Sposto R; Gore L, 2014, 'Nelarabine in Combination with Etoposide and Cyclophosphamide Is Active in First Relapse of Childhood T-Acute Lymphocytic Leukemia (T-ALL) and T-Lymphoblastic Lymphoma (T-LL)', Blood, 124, pp. 795 - 795, http://dx.doi.org/10.1182/blood.v124.21.795.795
    Journal articles | 2014
    Williams P; Wegner E; Ziegler DS, 2014, 'Outcomes in multifocal neuroblastoma as part of the neurocristopathy syndrome', Pediatrics, 134, http://dx.doi.org/10.1542/peds.2013-3340
    Journal articles | 2013
    Mateos MK; O'Brien TA; Oswald C; Ziegler DS; Cohn RJ; Russell SJ; Barbaric D; Marshall GM; Trahair TN; Gabriel M, 2013, 'Transplant-related mortality following allogeneic hematopoeitic stem cell transplantation for pediatric acute lymphoblastic leukemia: 25-year retrospective review', Pediatric Blood and Cancer, 60, pp. 1520 - 1527, http://dx.doi.org/10.1002/pbc.24559
    Journal articles | 2013
    Shah S; Schrader KA; Vijai J; Miething C; Hayes J; Klein RJ; Gao X; Kitzing T; Lowe SW; Offit K; Littman J; Offit L; Rau-Murthy R; Fleischut MH; Corines M; Manschreck C; Waanders E; Wei L; Ma J; Chen S-C; Song G; Cheng J; Raimondi SC; Roberts KG; Downing JR; Mullighan CG; Kuiper RP; Simons A; Timms AE; Wechsler J; Horwitz MS; Yang J; Zhang J; Wu G; Rusch M; Nagahawatte P; Meyers P; Bhojwani D; Sandlund JT; Jhanwar S; Murali R; Maslak P; Fleisher M; Murty VV; Schiffman JD; Onel K; Plon SE; Wheeler DA; Ritter D; Ziegler DS; Sutton R; Tucker K; Chenevix-Trench G; Li J; Huntsman DG; Hansford S; Senz J; Walsh T; Lee M; King M-C; Hahn CN; Scott HS; Lo SM; Levine RL; Viale A; Socci ND; Nathanson KL; Daly M; Lipkin SM; Altshuler D, 2013, 'A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia', Nature Genetics, 45, pp. 1226 - 1231, http://dx.doi.org/10.1038/ng.2754
    Journal articles | 2012
    Argent E; Emder PJ; Monagle P; Mowat DR; Petterson T; Russell SJ; Sachdev RR; Stone C; Ziegler DS, 2012, 'Australian paediatric surveillance unit study of haemoglobinopathies in australian children', Journal of Paediatrics and Child Health, 48, pp. 356 - 360, http://dx.doi.org/10.1111/j.1440-1754.2011.02236.x
    Journal articles | 2012
    Bock V; Ziegler DS; Wargon O; Gray PEA, 2012, 'Neonatal Sweet Syndrome: A potential marker of serious systemic illness', Pediatrics, 129, pp. e1353 - e1359, http://dx.doi.org/10.1542/peds.2011-1854
    Journal articles | 2012
    Gamble LD; Hogarty MD; Liu X; Ziegler DS; Marshall GM; Norris MD; Haber M, 2012, 'Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma', Frontiers in Oncology, 2, pp. 1 - 10, http://dx.doi.org/10.3389/fonc.2012.00162
    Journal articles | 2012
    Keating J; Tsoli M; Hallahan AR; Ingram WJ; Haber M; Ziegler DS, 2012, 'Targeting the inhibitor of apoptosis proteins as a novel therapeutic strategy in medulloblastoma', Molecular Cancer Therapeutics, 11, pp. 2654 - 2663, http://dx.doi.org/10.1158/1535-7163.MCT-12-0352
    Journal articles | 2012
    Ziegler D, 2012, 'Erratum: Treatment of diabetic neuropathy and neuropathic pain: How far have we come? (Diabetes Care (2008) 31 Suppl. 2, (S255-S261) DOI: 10.2337/dc08-s263)', Diabetes Care, 35, pp. 456, http://dx.doi.org/10.2337/dc12-rt02
    Journal articles | 2011
    Barbaro PM; Johnston K; Dalla-Pozza L; Cohn RJ; Wang YA; Marshall GM; Ziegler DS, 2011, 'Reduced incidence of second solid tumors in survivors of childhood Hodgkin's lymphoma treated without radiation therapy', Annals of Oncology, 22, pp. 2569 - 2574, http://dx.doi.org/10.1093/annonc/mdr013
    Journal articles | 2011
    Kamath V; Sugo E; Ziegler DS; Kwok B; Lukeis R, 2011, 'Atypical teratoid/rhaboid tumour arising in association with a pleomorphic xanthoastrocytoma: a case report', Pathology, 43, pp. S76 - S76, http://dx.doi.org/10.1016/s0031-3025(16)33261-5
    Journal articles | 2011
    McCowage G; Mrongovius R; Alvaro F; Cohn RJ; Ziegler DS; Oswald CM; White L, 2011, 'Treatment of children with poor risk solid tumors by further escalation of the VETOPEC regimen including very high-dose cyclophosphamide and peripheral stem cell support: An Australian and New Zealand children's hematology and oncology group study', Pediatric Blood and Cancer, 57, pp. 958 - 964, http://dx.doi.org/10.1002/pbc.23042
    Journal articles | 2011
    Ziegler D; Rosentock J; Portenoy R, 2011, 'Effective management of diabetic neuropathy - Pregabalin relieves the neuropathic pain', Diabetes Aktuell, 9, pp. 237, http://dx.doi.org/10.1055/s-0031-1286694
    Journal articles | 2011
    Ziegler DS; Keating J; Kesari S; Fast EM; Zawel L; Ramakrishnan N; Barnes J; Kieran MW; Van zanten SEMV; Kung AL, 2011, 'A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo', Neuro - Oncology, 13, pp. 820 - 829, http://dx.doi.org/10.1093/neuonc/nor066
    Journal articles | 2010
    Ueberberg S; Ziegler D; Schechinger W; Dietrich JW; Akinturk S; Klein HH; Schneider S, 2010, 'In vitro phage display in a rat beta cell line: A simple approach for the generation of a single-chain antibody targeting a novel beta cell-specific epitope', Diabetologia, 53, pp. 1384 - 1394, http://dx.doi.org/10.1007/s00125-010-1725-9
    Journal articles | 2009
    Satharasinghe K; Trahair TN; Barbaric D; O'Brien TA; Russell SJ; Cohn RJ; Marshall GM; Ziegler DS, 2009, 'False-positive MIBG scans with normal computed tomography imaging in patients with high-risk neuroblastoma', Journal of Clinical Oncology, 27, http://dx.doi.org/10.1200/JCO.2009.24.0036
    Journal articles | 2008
    Ziegler DS; Klung A, 2008, 'Therapeutic targeting of apoptosis pathways in cancer', Current Opinion Oncology, 20, pp. 97 - 103, http://dx.doi.org/10.1097/CCO.0b013e3282f310f6
    Journal articles | 2008
    Ziegler DS; Kung A; Kieran M, 2008, 'Anti-apoptosis mechanisms in malignant gliomas', Journal of Clinical Oncology, 26, pp. 493 - 500, http://dx.doi.org/10.1200/JCO.2007.13.9717
    Journal articles | 2008
    Ziegler DS; Wright R; Kesari S; Lemieux M; Tran M; Jain M; Zawei L; Kung A, 2008, 'Resistance of human glioblastoma multiformed cells to growth factor inhibitor of apoptosis proteins', The Journal of Clinical Investigation, 2118, pp. 3109 - 3122
    Journal articles | 2008
    Ziegler DS; Wright RD; Kesari S; Lemieux ME; Tran MA; Jain M; Zawel L; Kung AL, 2008, 'Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins', Journal of Clinical Investigation, 118, pp. 3109 - 3122, http://dx.doi.org/10.1172/JCI34120
    Journal articles | 2006
    Ziegler DS; Cohn RJ; McCowage G; Alvaro F; Oswald CM; Mrongovius R; White L, 2006, 'Efficacy of vincristine and etoposide with escalating cyclophosphamide in poor-prognosis pediatric brain tumors', Neuro - Oncology, 8, pp. 53 - 59, http://dx.doi.org/10.1215/S1522851705000463
    Journal articles | 2006
    Ziegler DS; McCowage G; Cohn RJ; White L, 2006, 'Long-term survival following a phase I/II trial with VETOPEC for solid tumors in childhood', Journal of Pediatric Hematology and Oncology, 28, pp. 40 - 42
    Journal articles | 2005
    Haysom L; Ziegler DS; Cohn RJ; Rosenberg A; Carroll SL; Kainer G, 2005, 'Retinoic acid may increase the risk of bone marrow transplant nephrology', Pediatric Nephrology, 20, pp. 534 - 538, http://dx.doi.org/10.1007/s00467-004-1775-7
    Journal articles | 2005
    Hocking B; Ziegler DS; Dalla Pozza L; Waters KD; Marshall GM, 2005, 'Advances in childhood leukaemia (multiple letters) [2]', Medical Journal of Australia, 182, pp. 364 - 365, http://dx.doi.org/10.5694/j.1326-5377.2005.tb06739.x
    Journal articles | 2005
    Ziegler DS; Cohn RJ; Duffy B; Sutton R; Norris MD, 2005, 'PCR for monoclonal gene rearrangements can differentiate infantile acute lymphoblastic leukemia from cytomegalovirus infection', Leukemia Research, 29, pp. 111 - 112, http://dx.doi.org/10.1016/j.leukres.2004.03.023
    Journal articles | 2005
    Ziegler DS; Dalla Pozza L; Waters K; Marshall GM, 2005, 'Advances in childhood leukaemia: successful clinical-trials research leads to individualised therapy', Medical Journal of Australia, 182, pp. 78 - 81
    Journal articles | 2005
    Ziegler DS; Piper AC; Sammut J, 2005, 'Physical injury in young children: The differential diagnosis must include child abuse (vol 41, pg 251, 2005)', JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 41, pp. 474 - 474, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000231566400004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2005
    Ziegler DS; Pozza LD; Waters KD; Marshall GM, 2005, 'Advances in childhood leukaemia - Reply', MEDICAL JOURNAL OF AUSTRALIA, 182, pp. 365 - 365, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000229273600017&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2005
    Ziegler DS; Pozza LD; Waters KD; Marshall GM, 2005, 'Advances in childhood leukaemia', Medical Journal of Australia, 182, pp. 364 - 365, http://dx.doi.org/10.5694/j.1326-5377.2005.tb06740.x
    Journal articles | 2005
    Ziegler DS; Russell SJ; Rozenberg G; James CA; Trahair TN; O'Brien TA, 2005, 'Goats' milk quackery', Journal of Paediatrics and Child Health, 41, pp. 569 - 571, http://dx.doi.org/10.1111/j.1440-1754.2005.00723.x
    Journal articles | 2005
    Ziegler DS; Sammut JF; Piper AC, 2005, 'Assessment and follow up of suspected child abuse in preschool children with fractures seen in a general hospital emergency department.', Journal of Paediatrics and Child Health (Vol. 48, Suppl. 2, 2012, 1–13), 41, pp. 251 - 255, http://dx.doi.org/10.1111/j.1440-1754.2005.00605.x
    Journal articles | 2003
    Scanlon DM; Ziegler DS; Mantzouranis EC; Boicos SA; Bagourakis GS, 2003, 'Throat clearing in asthma [5] (multiple letters)', New England Journal of Medicine, 349, pp. 194 - 195, http://dx.doi.org/10.1056/NEJM200307103490220
    Journal articles | 2001
    Ziegler D; Bent G, 2001, 'Caustic-induced upper airway obstruction responsive to nebulized adrenaline [5]', Pediatrics, 107, pp. 807 - 808, http://dx.doi.org/10.1542/peds.107.4.807
    Journal articles | 2001
    Ziegler DS; Bent GP, 2001, 'Upper airway obstruction induced by a caustic substance found responsive to nebulised adrenaline [3]', Journal of Paediatrics and Child Health, 37, pp. 524 - 525, http://dx.doi.org/10.1046/j.1440-1754.2001.0742c.x
  • Preprints | 2023
    Duchatel RJ; Jackson ER; Parackal SG; Sun C; Daniel P; Mannan A; Findlay IJ; Staudt D; Germon ZP; Laternser S; Kiltschewskij D; Kearney PS; Fairuz M; Jamaluddin B; Douglas AM; Beitaki T; Persson M; Manning EE; Murray HC; Verrills NM; Skerrett-Byrne DA; Nixon B; Hua S; Fatima V-M; Tsoli M; Ziegler DS; Cairns MJ; Raabe E; Vitanza NA; Koschmann C; Alvaro F; Dayas CV; Tinkle CL; Eisenstat DD; Firestein R; Mueller S; Nazarian J; Cain JE; Dun MD, 2023, PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma, , http://dx.doi.org/10.1101/2023.04.17.537256
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Data from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.c.6767498
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Data from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.c.6767498.v1
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Data from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.c.6767498.v2
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Data from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.c.6767498.v3
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures and Figure Legends from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.24000213
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures and Figure Legends from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.24000213.v1
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.23808560
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.23808560.v1
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.23952251
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.23952251.v1
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.24000210
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Figures from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.24000210.v1
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Materials and Methods from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.24000207
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Materials and Methods from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.24000207.v1
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Tables S1-S7 from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.24000204
    Other | 2023
    Mayoh C; Mao J; Xie J; Tax G; Chow S-O; Cadiz R; Pazaky K; Barahona P; Ajuyah P; Trebilcock P; Malquori A; Gunther K; Avila A; Yun DY; Alfred S; Gopalakrishnan A; Kamili A; Wong M; Cowley MJ; Jessop S; Lau LMS; Trahair TN; Ziegler DS; Fletcher JI; Gifford AJ; Tsoli M; Marshall GM; Haber M; Tyrrell V; Failes TW; Arndt GM; Lock RB; Ekert PG; Dolman MEM, 2023, Supplementary Tables S1-S7 from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer, , http://dx.doi.org/10.1158/0008-5472.24000204.v1
    Conference Abstracts | 2023
    Nagabushan S; Hamayun M; Fardell JE; Donoghoe M; Bland E; Bye A; Jacobson E; Manoharan N; Ziegler DS; McLoone JK; Johnson AM; Cohn RJ, 2023, 'LGG-11. COGNITIVE, ACADEMIC, AND QUALITY OF LIFE OUTCOMES IN SURVIVORS OF PEDIATRIC LOW-GRADE GLIOMA: CHALLENGING THE ‘BENIGN TUMOR’ PERCEPTION', in Neuro-Oncology, Oxford University Press (OUP), Vol. 25, pp. i57 - i58, http://dx.doi.org/10.1093/neuonc/noad073.221
    Conference Abstracts | 2022
    Brown MP; Gargett T; Ebert LM; Truong N; Sedivakova K; Kollis PM; Yu W; Yeo E; Vittorio O; Ziegler DS, 2022, 'Immunotherapy: IN VITRO STUDIES IN SUPPORT OF GD2-SPECIFIC CAR-T CELL THERAPY FOR AGGRESSIVE ADULT AND PEDIATRIC BRAIN TUMORS', in Cytotherapy, Elsevier BV, Vol. 24, pp. S125 - S125, http://dx.doi.org/10.1016/s1465-3249(22)00336-x
    Conference Abstracts | 2022
    Cooney T; DeWire-Schottmiller M; Lane A; Saab R; Bandopadhayay P; Dorris K; Packer R; Kilburn L; Minturn J; Dodgshun A; Parkin S; Goldman S; Sandler E; Greiner R; Gottardo N; Dholaria H; Coven S; Hassall T; Hansford J; Samson Y; Leary S; Bartels U; Fonseca A; Bouffet E; Tinkle C; Monje M; Fisher P; Ziegler D; Chintagumpala M; Wagner L; Koschmann C; Leach J; Jones B; Benito EC; Bond H; Chaney B; Black K; Asher A; Fouladi M; Hoffman L; Warren K, 2022, 'PATTERNS OF CEREBROSPINAL FLUID DIVERSION AND SURVIVAL IN CHILDREN WITH DIFFUSE INTRINSIC PONTINE GLIOMA: A REPORT FROM THE INTERNATIONAL DIFFUSE INTRINSIC PONTINE GLIOMA REGISTRY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 24, pp. 23 - 24, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000840122400084&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2022
    Daniel P; Sun C; Koptyra M; Drinkwater C; Chew N; Bradshaw G; Loi M; Shi C; Tourchi M; Parackal S; Chong WC; Fernando D; Adjumain S; Hoang N; Habarakada D; Sooraj D; Crombie D; Zhukova N; Jones C; Rubens J; Raabe E; Vinci M; Dun M; Ludlow L; Nazarian J; Fletcher J; Ekert P; Ziegler D; Loh AHP; Low SYY; Monje M; Neeman N; Williams B; Resnick A; Gough D; Cain J; Firestein R, 2022, 'THE CHILDHOOD BRAIN CANCER CELL LINE ATLAS: A RESOURCE FOR BIOMARKER IDENTIFICATION AND THERAPEUTIC DEVELOPMENT', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, GERMANY, Hamburg, Vol. 24, pp. 172 - 172, presented at 20th International Symposium on Pediatric Neuro-Oncology (ISPNO) / Annual Meeting of the Brain-Tumor-Group-of-SIOP-Europe (SIOPE-BTG), GERMANY, Hamburg, 11 June 2022 - 15 June 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000840122400644&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2022
    Das A; Morgenstern D; Bianchi V; Sudhaman S; Edwards M; Stengs L; Larouche V; Samuel D; Van Damme A; Gass D; Ziegler D; Bielack S; Zelcer S; Yalon M; Constantini S; Sarosiek T; Libionka W; Nichols K; De Mola RL; Bielamowicz K; Sabel M; Frojd C; Wood MD; Sous Migueis JC; Abongwa C; Yen LY; Stearns D; Opocher E; Bhatia K; Sen S; Quiroga Cantero E; Solano Paez P; Crooks B; Magimairajan V; Reddy A; Adamski J; Mason G; Lindhorst S; Aronson M; Ertl-Wagner B; Hawkins C; Bouffet E; Tabori U, 2022, 'DUAL CTLA4/PD-1 BLOCKADE IMPROVES SURVIVAL FOR REPLICATION-REPAIR DEFICIENT HIGH-GRADE GLIOMAS FAILING SINGLE AGENT PD-1 INHIBITION: AN IRRDC STUDY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, GERMANY, Hamburg, Vol. 24, pp. 84 - 84, presented at 20th International Symposium on Pediatric Neuro-Oncology (ISPNO) / Annual Meeting of the Brain-Tumor-Group-of-SIOP-Europe (SIOPE-BTG), GERMANY, Hamburg, 11 June 2022 - 15 June 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000840122400309&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints | 2022
    Gargett T; Ebert L; Truong NTH; Kollis P; Sedivakova K; Yu W; Yeo ECF; Wittwer N; Gliddon B; Tea M; Ormsby R; Poonnoose S; Nowicki J; Vittorio O; Ziegler D; Pitson S; Brown M, 2022, GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma, , http://dx.doi.org/10.1101/2022.05.01.490250
    Conference Abstracts | 2022
    Gereis J; Hetherington K; Robertson E; Ziegler D; Wakefield C, 2022, 'PARENTS' AND PATIENTS' UNDERSTANDING OF A PRECISION MEDICINE TRIAL FOR HIGH-RISK CHILDHOOD CANCER', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 69, pp. S399 - S399, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000859203901450&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2022
    Holliday H; Ehteda A; Khan A; Krug B; Rouaen JRC; Jayatilleke N; Mayoh C; Vittorio O; Jabado N; Tsoli M; Ziegler DS, 2022, 'DIPG-06. Uncovering the FACTs in Diffuse Midline Glioma (DMG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 24, pp. i18 - i18, http://dx.doi.org/10.1093/neuonc/noac079.063
    Conference Abstracts | 2022
    Holliday H; Ehteda A; Khan A; Krug B; Rouaen JRC; Jayatilleke N; Mayoh C; Vittorio O; Jabado N; Tsoli M; Ziegler DS, 2022, 'UNCOVERING THE FACTS IN DIFFUSE MIDLINE GLIOMA (DMG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 24, pp. 18 - 18, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000840122400065&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2022
    Landi DB; Ziegler DS; Franson AF; Baxter PA; Leary S; Larouche V; Waanders AJ; Van der Lugt J; McCowage GB; Doz F; Jabado N; Schiavello E; Zapotocky M; Cornelio I; Blackman SC; Da Costa D; Cox MC; Witt O; Kilburn LB; Hansford JR, 2022, 'FIREFLY-1 (PNOC 026): A phase 2 study to evaluate the safety and efficacy of tovorafenib (DAY101) in pediatric patients with RAF-altered recurrent or progressive low-grade glioma or advanced solid tumors.', in Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, pp. TPS10062 - TPS10062, http://dx.doi.org/10.1200/jco.2022.40.16_suppl.tps10062
    Preprints | 2022
    Lilly JV; Rokita JL; Mason JL; Patton T; Stefankiewiz S; Higgins D; Trooskin G; Larouci CA; Arya K; Appert E; Heath AP; Zhu Y; Brown MA; Zhang B; Farrow BK; Robins S; Morgan AM; Nguyen TQ; Frenkel E; Lehmann K; Drake E; Sullivan C; Plisiewicz A; Coleman N; Patterson L; Koptyra M; Helili Z; Van Kuren N; Young N; Kim MC; Friedman C; Lubneuski A; Blackden C; Williams M; Baubet V; Tauhid L; Galanaugh J; Boucher K; Ijaz H; Cole KA; Choudhari N; Santi M; Moulder RW; Waller J; Rife W; Diskin SJ; Mateos M; Parsons DW; Pollack IF; Goldman S; Leary S; Caporalini C; Buccoliero AM; Scagnet M; Haussler D; Hanson D; Firestein R; Cain J; Phillips JJ; Gupta N; Mueller S; Grant G; Monje-Deisseroth M; Partap S; Greenfield JP; Hashizume R; Smith A; Zhu S; Johnston JM; Fangusaro JR; Miller M; Wood MD; Gardner S; Carter CL; Prolo LM; Pisapia J; Pehlivan K; Franson A; Niazi T; Rubin J; Abdelbaki M; Ziegler DS; Lindsay HB; Stucklin AG; Gerber N; Vaske OM; Quinsey C; Rood BR; Nazarian J; Raabe E; Jackson EM; Stapleton S; Lober RM; Kram DE; Koschmann C; Storm PB; Lulla RR; Prados M; Resnick AC; Waanders AJ, 2022, The Children’s Brain Tumor Network (CBTN) - Accelerating Research in Pediatric Central Nervous System Tumors through Collaboration and Open Science, , http://dx.doi.org/10.1101/2022.10.14.511975
    Preprints | 2022
    Mayoh C; Gifford A; Terry R; Lau LMS; Wong M; Rao P; Shai-Hee T; Saletta F; Khuong-Quang D-A; Qin V; Mateos M; Meyran D; Miller K; Yuksel A; Mould EVA; Bowen-James R; Govender D; Senapati A; Zhukova N; Omer N; Dholaria H; Alvaro F; Tapp H; Diamond Y; Pozza LD; Moore A; Nicholls W; Gottardo N; McCowage G; Hansford J; Khaw S-L; Wood P; Catchpoole D; Cottrell C; Mardis E; Marshall G; Tyrrell V; Haber M; Ziegler D; Vittorio O; Trapani J; Cowley M; Neeson P; Ekert P, 2022, A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer, , http://dx.doi.org/10.1101/2022.09.16.508179
    Conference Abstracts | 2022
    Mayoh C; Meyran D; Nguyen T; Darcy C; Ziegler D; Haber M; Trapani J; Ekert P; Neeson P, 2022, 'PRECISION MEDICINE REVEALS A HETEROGENOUS TUMOUR IMMUNE MICROENVIRONMENT IN PAEDIATRIC GLIOMAS', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 69, pp. S327 - S328, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000859203901292&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2022
    Mazariego CG; Dobson M; McKay S; McGill B; Daly R; Wakefield C; Ziegler D; Taylor N, 2022, 'Designing for implementation: co-design of a paediatric oncology medicines database (ProCure) to support complex care provision for children with a hard-to-treat cancer', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, Vol. 18, pp. 229 - 229, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000871956500395&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2022
    Michniewicz F; Bell J; Saletta F; Watkinson T; Mercatelli D; Giorgi FM; Barlow CK; Faridi P; Tsoli M; Ziegler D; Vittorio O, 2022, 'COPPER CHELATION THERAPY TARGETS S-ADENOSYLMETHIONINE (SAM) METABOLISM AND EPIGENETIC REGULATORS IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, GERMANY, Hamburg, Vol. 24, pp. 22 - 22, presented at 20th International Symposium on Pediatric Neuro-Oncology (ISPNO) / Annual Meeting of the Brain-Tumor-Group-of-SIOP-Europe (SIOPE-BTG), GERMANY, Hamburg, 11 June 2022 - 15 June 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000840122400079&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2022
    Michniewicz F; Bell J; Saletta F; Watkinson T; Mercatelli D; Giorgi FM; Barlow CK; Faridi P; Tsoli M; Ziegler D; Vittorio O, 2022, 'DIPG-20. Copper chelation therapy targets S-adenosylmethionine (SAM) metabolism and epigenetic regulators in diffuse intrinsic pontine glioma (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 24, pp. i22 - i22, http://dx.doi.org/10.1093/neuonc/noac079.077
    Conference Posters | 2022
    Michniewicz F; Saletta F; Watkinson T; Mercatelli D; Giorgi FM; Bell J; Tsoli M; Ziegler D; Vittorio O, 2022, 'Abstract 5716: Using copper chelating agents to simultaneously target epigenetic mechanisms and receptor tyrosine kinase (RTK) signaling in diffuse intrinsic pontine glioma (DIPG)', Vol. 82, pp. 5716 - 5716, http://dx.doi.org/10.1158/1538-7445.am2022-5716
    Conference Papers | 2022
    Michniewicz F; Saletta F; Watkinson T; Mercatelli D; Giorgi FM; Bell J; Tsoli M; Ziegler D; Vittorio O, 2022, 'Using copper chelating agents to simultaneously target epigenetic mechanisms and receptor tyrosine kinase (RTK) signaling in diffuse intrinsic pontine glioma (DIPG)', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), LA, New Orleans, 08 April 2022 - 13 April 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000892509503338&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2022
    Michniewicz F; Saletta F; Watkinson T; Mercatelli D; Giorgi FM; Bell J; Tsoli M; Ziegler D; Vittorio O, 2022, 'Using copper chelating agents to simultaneously target epigenetic mechanisms and receptor tyrosine kinase (RTK) signaling in diffuse intrinsic pontine glioma (DIPG).', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, LA, New Orleans, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), LA, New Orleans, 08 April 2022 - 13 April 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000892509501275&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints | 2022
    Poursani EM; Mercatelli D; Raninga P; Bell JL; Saletta F; Kohane FV; Zheng Y; Rouaen J; Jue TR; Michniewicz FT; Kasiou E; Tsoli M; Cirillo G; Waters S; Shai-Hee T; Valli E; Brettle M; Whan R; Vahadat L; Ziegler D; Lock JG; Giorgi FM; Khanna KK; Vittorio O, 2022, Copper chelation inhibits TGF-β pathways and suppresses epithelial-mesenchymal transition in cancer, , http://dx.doi.org/10.1101/2022.10.03.510707
    Conference Abstracts | 2022
    Sanguino YC; de la Fuente LR; Kisswani D; Kearney P; Jackson E; Duchatel R; Holliday H; Jabado N; Tsoli M; Ziegler D; Dun M; Mora FV, 2022, 'DIPG-37. Exploring the role of the epigenetic factor H2A.Z acetylation in DIPG', in Neuro-Oncology, Oxford University Press (OUP), Vol. 24, pp. i26 - i27, http://dx.doi.org/10.1093/neuonc/noac079.094
    Conference Abstracts | 2022
    Sanguino YC; de la Fuente LR; Kisswani D; Kearney P; Jackson E; Duchatel R; Holliday H; Jabado N; Tsoli M; Ziegler D; Dun M; Mora FV, 2022, 'EXPLORING THE ROLE OF THE EPIGENETIC FACTOR H2A.Z ACETYLATION IN DIPG', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, GERMANY, Hamburg, Vol. 24, pp. 26 - 27, presented at 20th International Symposium on Pediatric Neuro-Oncology (ISPNO) / Annual Meeting of the Brain-Tumor-Group-of-SIOP-Europe (SIOPE-BTG), GERMANY, Hamburg, 11 June 2022 - 15 June 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000840122400096&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2022
    Ung C; Upton DH; Venkat P; Pandher R; Curnis F; Corti A; Nicolazzo J; Mayoh C; Tsoli M; Ziegler DS, 2022, 'DIPG CELLS ALTER THE PERMEABILITY OF THE BLOOD-BRAIN BARRIER IN THE BRAINSTEM LEADING TO TREATMENT FAILURE', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, GERMANY, Hamburg, Vol. 24, pp. 22 - 22, presented at 20th International Symposium on Pediatric Neuro-Oncology (ISPNO) / Annual Meeting of the Brain-Tumor-Group-of-SIOP-Europe (SIOPE-BTG), GERMANY, Hamburg, 11 June 2022 - 15 June 2022, http://dx.doi.org/10.1093/neuonc/noac079.078
    Conference Abstracts | 2022
    Upton D; George S; Liu J; Cai DD; Su SY-C; Rayner B; Tsoli M; Ziegler D, 2022, 'DIPG-08. The development of ACT001 as a novel therapeutic for diffuse intrinsic pontine gliomas', in Neuro-Oncology, Oxford University Press (OUP), Vol. 24, pp. i19 - i19, http://dx.doi.org/10.1093/neuonc/noac079.065
    Conference Abstracts | 2022
    Upton D; George S; Liu J; Cai DD; Su SY-C; Rayner B; Tsoli M; Ziegler D, 2022, 'THE DEVELOPMENT OF ACT001 AS A NOVEL THERAPEUTIC FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 24, pp. 19 - 19, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000840122400067&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2022
    Wood P; Desai J; Waldeck K; Cain J; Gottardo N; Strong R; Kinross K; Carr M; Jones J; Wong L; Ziegler D; Hansford J; Michael M; Ashley D, 2022, 'ATRT-17. A phase II study of continuous low dose panobinostat in paediatric patients with malignant rhabdoid tumours and atypical teratoid rhabdoid tumours.', in Neuro-Oncology, Oxford University Press (OUP), Vol. 24, pp. i6 - i7, http://dx.doi.org/10.1093/neuonc/noac079.016
    Conference Papers | 2021
    Das A; Morgenstern D; Sudhaman S; Coblentz A; Chung J; Stone S; Alsafwani N; Cabric V; Nobre L; Bianchi V; Edwards M; Sambira L; Constantini S; Dvir R; Yalon-Oren M; Campino G; Caspi S; Larouche V; Reddy A; Osborn M; Mason G; Lindhorst S; Bronsema A; Magimairajan V; Opocher E; Mola R; Sabel M; Frojd C; Sumerauer D; Samuel D; Cole K; Chiaravalli S; Massimino M; Tomboc P; Ziegler D; George B; Damme A; Hijiya N; Gass D; Mcgee R; Mordechai O; Bowers D; Laetsch T; Lossos A; Blumenthal D; Sarosiek T; Yen L; Knipstein J; Bendel A; Hoffmann L; Luna-Fineman S; Zimmermann S; Scheers I; Nichols K; Zapotocky M; Hansford J; Maris J; Dirks P; Taylor M; Kulkarni A; Shroff M; Tsang D; Villani A; Aronson M; Durno C; Shlein A; Malkin D; Getz G; Maruvka Y; Ohashi P; Hawkins C; Pugh T; Bouffet E; Tabori U, 2021, 'Mutation and Microsatellite Burden Predict Response to PD-1 Inhibition in Children With Germline DNA Replication Repair Deficiency', in PEDIATRIC BLOOD & CANCER, WILEY, pp. S95 - S96, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000708132100190&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2021
    Ehteda A; Simon S; Franshaw L; Giorgi FM; Liu J; Hayden E; Rouaen J; Pang CNI; Pandher R; Mayoh C; Tang Y; Khan A; Ung C; Kankean A; Lehmann R; Shen S; Gopalakrishnan A; Trebilcock P; Gurova K; Gudkov A; Norris MD; Haber M; Vittorio O; Tsoli M; Ziegler DS, 2021, 'TARGETING FACILITATES CHROMATIN TRANSCRIPTION (FACT) AS A NOVEL STRATEGY THAT ENHANCES RESPONSE TO HISTONE DEACETYLASE (HDAC) INHIBITION IN DIPG', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 23, pp. 18 - 19, http://dx.doi.org/10.1093/neuonc/noab090.075
    Conference Abstracts | 2021
    Khan A; Gamble L; Upton D; Yu D; Pandher R; Mayoh C; Burns MR; Norris MD; Haber M; Tsoli M; Ziegler DS, 2021, 'POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 23, pp. 40 - 41, http://dx.doi.org/10.1093/neuonc/noab090.163
    Conference Presentations | 2021
    Lau L; Khuong-Quang D-A; Nagabushan S; Senapati A; Barahona P; Ajuyah P; Altekoester A-K; Wong M; Mayoh C; Mould E; Fuentes-Bolanos N; Zhukova N; Cowley M; Ekert P; Tyrrell V; Trahair T; Haber M; Marshall G; Ziegler D, 2021, 'Precision Medicine for High-Risk Paediatric Cancers - Molecular Tumour Board Recommendations and Treatment Responses (Zero Childhood Cancer Program)', Vol. 68, pp. S53 - S53, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000708132100110&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2021
    Mayoh C; Terry RL; Wong M; Lau LM; Khuong-Quang DA; Mateos MK; Tyrrell V; Haber M; Ziegler DS; Cowley MJ; Trapani JA; Neeson PJ; Ekert PG, 2021, 'Abstract 3044: The unexplored immune landscape of high-risk pediatric cancers', in Cancer Research, American Association for Cancer Research (AACR), Vol. 81, pp. 3044 - 3044, presented at Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA, http://dx.doi.org/10.1158/1538-7445.am2021-3044
    Conference Abstracts | 2021
    Mayoh C; Terry RL; Wong M; Lau LM; Khuong-Quang DA; Mateos MK; Tyrrell V; Haber M; Ziegler DS; Cowley MJ; Trapani JA; Neeson PJ; Ekert PG, 2021, 'The unexplored immune landscape of high-risk pediatric cancers.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 81, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000680263506379&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2021
    Ung C; Upton D; Tsoli M; Ziegler D, 2021, 'HGG-10. THE BLOOD-BRAIN BARRIER IN DIPG: INVESTIGATING REGION-SPECIFIC DIFFERENCES IN PERMEABILITY', in Neuro-Oncology, Oxford University Press (OUP), Vol. 23, pp. i19 - i19, http://dx.doi.org/10.1093/neuonc/noab090.076
    Conference Abstracts | 2021
    Upton D; George S; Liu J; Cai D; Su SY-C; Manoharan N; Foresto S; Hassall T; Tsoli M; Ziegler D, 2021, 'ACT001-A PROMISING THERAPEUTIC FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 23, pp. 20 - 20, http://dx.doi.org/10.1093/neuonc/noab090.080
    Conference Abstracts | 2021
    Upton D; Valvi S; Liu J; Yeung N; George S; Ung C; Khan A; Franshaw L; Ehteda A; Shen H; Orienti I; Farruggia G; Reynolds P; Tsoli M; Ziegler D, 2021, 'POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS IDENTIFIED THROUGH HIGH THROUGHPUT DRUG SCREENING', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 23, pp. 42 - 42, http://dx.doi.org/10.1093/neuonc/noab090.169
    Conference Abstracts | 2020
    Barahona P; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Haber M; Lock RB; Marshall GM; Mayoh C; Mould E; Nagabushan S; Norris M; O’Brien T; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Ziegler DS; Tyrrell VJ; Ekert P; Cowley MJ; Lau L; Quang D-AK, 2020, 'Abstract A52: Zero Childhood Cancer (ZERO): A comprehensive precision medicine platform for children with high-risk cancer', in Cancer Research, American Association for Cancer Research (AACR), Vol. 80, pp. A52 - A52, presented at Abstracts: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada, http://dx.doi.org/10.1158/1538-7445.pedca19-a52
    Conference Abstracts | 2020
    Barahona P; Sherstyuk A; Cowley M; Ekert P; Kirk J; Khuong-Quang D-A; Kumar A; Lau L; Mayoh C; Marshall G; Moud E; O’Brien T; Pinese M; Thomas D; Tyrell V; Ziegler D; Haber M; Tucker K; Fuentes-Bolanos NA; Warby M, 2020, 'Abstract A03: Prevalence and spectrum of germline mutations in children with high-risk cancer', in Cancer Research, American Association for Cancer Research (AACR), Vol. 80, pp. A03 - A03, presented at Abstracts: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada, http://dx.doi.org/10.1158/1538-7445.pedca19-a03
    Conference Papers | 2020
    Chung J; Maruvka Y; Sudhaman S; Kelly J; Haradhvala N; Bianchi VJ; Edwards M; Forster V; Nunes N; Galati M; Komosa M; Deshmukh S; Cabric V; Davidson S; Zatzman M; Light N; Hayes R; Brunga L; Anderson N; Ho B; Hodel K; Siddaway R; Morrissy AS; Bowers D; Larouche V; Bronsema A; Osborn M; Cole K; Opocher E; Mason G; Thomas G; George B; Ziegler D; Lindhorst S; Issai VM; Oren M; Reddy A; Massimino M; Tomboc P; Van Damme A; Lossos A; Durno C; Aronson M; Morgenstern D; Bouffet E; Huang A; Taylor M; Vilani A; Malkin D; Hawkins C; Pursell Z; Shlien A; Kunkel T; Getz G; Tabori U, 2020, 'DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Nomral and Malignant Human Cells', in PEDIATRIC BLOOD & CANCER, WILEY, pp. S4 - S5, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000581769200008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2020
    Das A; Bianchi V; Edwards M; Varghese N; Sudhaman S; Farah R; Dvir R; Reddy A; Raskin S; Hansford J; Hamid SA; Hsu S; Yen LY; Abu Quider A; Ghalibafian M; Koustenis E; Al-Battashi A; Mason G; Lee J; Bell D; Stearns D; Ziegler D; Zapotocky M; Lasaletta A; Kulkarni A; Tsang DS; Laperriere N; Hawkins C; Bouffet E; Ramaswamy V; Tabori U, 2020, 'POOR SURVIVAL IN REPLICATION REPAIR DEFICIENT HYPERMUTANT MEDULLOBLASTOMA AND CNS EMBRYONAL TUMORS: A REPORT FROM THE INTERNATIONAL RRD CONSORTIUM', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 407 - 407, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100561&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2020
    Das A; Bianchi VJ; Edwards M; Sudhaman S; Varghese N; Farah R; Dvir R; Reddy A; Raskin S; Hansford J; Hamid SA; Saunders H; Yen LY; Abu Quider A; Ghalibafian M; Koustenis E; Al-Battashi A; Stearns D; Ziegler D; Zapotocky M; Lassaletta A; Mason G; Lee J; Kulkarni A; Tsang D; Laperriere N; Hawkins C; Bouffet E; Ramaswamy V; Tabori U, 2020, 'Poor Survival in DNA-Replication Repair Deficient (RRD) Medulloblastoma and CNS-Embryonal Tumors is Related to High-Risk Genomic Features: A Report From the International RRD Consortium', in PEDIATRIC BLOOD & CANCER, WILEY, pp. S54 - S55, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000581769200106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2020
    Dodgshun A; Fukuoka K; Edwards M; Bianchi V; Sexton-Oates A; Larouche V; Magimairajan V; Lindhorst S; Yalon M; Mason G; Crooks B; Constantini S; Massimino M; Chiaravalli S; Ramdas J; Mason W; Shamvil A; Farah R; Van Damme A; Opocher E; Hamid SA; Ziegler D; Samuel D; Cole KA; Tomboc P; Stearns D; Thomas G; Lossos A; Sullivan M; Hansford JR; Jones D; Mackay A; Jones C; Ramaswamy V; Hawkins C; Bouffet E; Tabori U, 2020, 'DIAGNOSTIC AND BIOLOGICAL ROLE OF METHYLATION PATTERNS IN REPLICATION REPAIR DEFICIENT HIGH GRADE GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 347 - 348, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100308&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2020
    Dong-Anh K-Q; Nagabushan S; Manoharan N; Arndt G; Barahona P; Cowley MJ; Ekert PG; Failes T; Bolanos NF; Gauthier M; Gifford AJ; Haber M; Kumar A; Lock RB; Marshall GM; Mayoh C; Mould E; Norris MD; Gopalakrishnan A; Omer N; Trebilcock P; Trahair TN; Tsoli M; Tucker K; Wong M; Tyrrell V; Lau L; Ziegler DS, 2020, 'PRECISION MEDICINE FOR PAEDIATRIC HIGH-GRADE DIFFUSE MIDLINE GLIOMAS - RESULTS FROM THE ZERO CHILDHOOD CANCER COMPREHENSIVE PRECISION MEDICINE PROGRAM', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 22, pp. 302 - 302, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100118&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2020
    Duchatel RJ; Mannan A; Jackson ER; Staudt D; Skerrett-Byrne DA; Jamaluddin MFB; Woldu AS; Douglas A; Hulleman E; Carcaboso AM; Monje M; Alvaro F; Tsoli M; Ziegler DS; Dun MD, 2020, 'DIPG-29. PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE (PI3K) INHIBITION DRIVES PROTEIN KINASE C ACTIVATION (PKC) IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii292 - iii293, http://dx.doi.org/10.1093/neuonc/noaa222.078
    Conference Abstracts | 2020
    Ehteda A; Franshaw L; Liu J; Joshi S; Simon S; Pang CNI; Giorgi F; Pandher R; Ung C; Tolhurst O; Mayoh C; Khan A; Hayden E; Gopalakrishnan A; Trebilcock P; Upton D; Lehmann R; George S; Vittorio O; Tsoli M; Gurova K; Gudkov AG; Norris MD; Haber M; Ziegler DS, 2020, 'DIPG-27. TARGETING FACILITATES CHROMATIN TRANSCRIPTION (FACT) AS A NOVEL STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) THAT ENHANCES RESPONSE TO HISTONE DEACETYLASE (HDAC) INHIBITION', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii292 - iii292, http://dx.doi.org/10.1093/neuonc/noaa222.076
    Conference Papers | 2020
    Ehteda A; Franshaw L; Liu J; Joshi S; Simon S; Pang CNI; Giorgi F; Pandher R; Ung C; Tolhurst O; Mayoh C; Khan A; Hayden E; Gopalakrishnan A; Trebilcock P; Upton D; Lehmann R; George S; Vittorio O; Tsoli M; Gurova K; Gudkov AG; Norris MD; Haber M; Ziegler DS, 2020, 'TARGETING FACILITATES CHROMATIN TRANSCRIPTION (FACT) AS A NOVEL STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) THAT ENHANCES RESPONSE TO HISTONE DEACETYLASE (HDAC) INHIBITION', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 292 - 292, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100077&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2020
    Ercan A; Durno C; Bianchi V; Edwards M; Aronson M; Villani A; Bouffet E; Al-Battashi A; Alharbi M; Basel D; Bedgood R; Bendel A; Blumenthal D; Bornhorst M; Bronsema A; Cairney E; Caroll S; Chamdin A; Chiaravalli S; Constantini S; Das A; Dvir R; Farah R; Foulkes W; Frenkel Z; Gardner S; Ghalibafian M; Gilpin C; Goudie C; Hamid SA; Hampel H; Hansford J; Harlos C; Hijiya N; Saunders H; Kamihara J; Knipstein J; Koschmann C; Larouche V; Lassaletta A; Lindhorst S; Ling S; Link M; DeMola RL; Luiten R; Lurye M; Maciaszek J; Issai VM; Maher O; Massimino M; Mushtaq N; Newmark M; Nicholas G; Nichols K; Nicolaides T; Opocher E; Osborn M; Oshrine B; Pearlman R; Pettee D; Rapp J; Rashid M; Reddy A; Reichman L; Remke M; Robbins G; Sabel M; Samuel D; Scheers I; Sen S; Stearns D; Sumerauer D; Swallow C; Taylor L; Toledano H; Tomboc P; Van Damme A; Winer I; Yalon M; Yen LY; Zapotocky M; Zelcer S; Ziegler D; Zimmermann S; Azad VF; Roy S; Tabori U, 2020, 'Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Syndrome Who Undergo a Surveillance Protocol: A Report From the International Replication Repair Deficiency Consortium', in PEDIATRIC BLOOD & CANCER, WILEY, pp. S17 - S18, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000581769200033&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2020
    Ercan AB; Durno C; Bianchi VJ; Edwards M; Aronson M; Bouffet E; Al-Battashi A; Alharbi M; Basel D; Bedgood R; Bendel A; Blumenthal DT; Bornhorst M; Bronsema A; Cairney E; Carroll S; Chamdin A; Chiaravalli S; Constantini S; Das A; Dvir R; Farah R; Foulkes W; Frenkel Z; Gardner S; Ghalibafian M; Gilpin C; Goudie C; Hamid SA; Hansford J; Harlos C; Hijiya N; Hsu S; Kamihara J; Knipstein J; Koschmann C; Larouche V; Lassaletta A; Lindhorst S; Ling S; Link M; De Mola RL; Luiten R; Lurye M; Maciaszek J; Magimairajan V; Maher O; Massimino M; Mushtaq N; Newmark M; Nicholas G; Nichols K; Nicolaides T; Opocher E; Osborn M; Oshrine B; Pearlman R; Pettee D; Rapp J; Rashid M; Reddy A; Reichman L; Remke M; Robbins G; Sabel M; Samuel D; Scheers I; Sen S; Stearns D; Sumerauer D; Swallow C; Taylor L; Toledano H; Tomboc P; Van Damme A; Winer I; Yalon M; Yen LY; Zapotocky M; Azad VF; Zelcer S; Ziegler D; Zimmerman S; Tabori U, 2020, 'SURVIVAL BENEFIT FOR INDIVIDUALS WITH CONSTITUTIONAL MISMATCH REPAIR DEFICIENCY SYNDROME AND BRAIN TUMORS WHO UNDERGO SURVEILLANCE PROTOCOL. A REPORT FROM THE INTERNATIONAL REPLICATION REPAIR CONSORTIUM', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 445 - 446, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100729&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2020
    Franshaw L; Hayden E; Joshi S; Liu J; Ehteda A; Pang CNI; Tsoli M; Ziegler DS, 2020, 'DIPG-14. TARGETING POLO-LIKE KINASE 1 IN COMBINATION WITH KEY ONCOGENIC DRIVERS IN DIPG: FROM SINGLE AGENT TO COMBINATION STRATEGIES', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii289 - iii289, http://dx.doi.org/10.1093/neuonc/noaa222.064
    Conference Papers | 2020
    Franshaw L; Hayden E; Joshi S; Liu J; Ehteda A; Pang CNI; Tsoli M; Ziegler DS, 2020, 'TARGETING POLO-LIKE KINASE 1 IN COMBINATION WITH KEY ONCOGENIC DRIVERS IN DIPG: FROM SINGLE AGENT TO COMBINATION STRATEGIES', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 289 - 289, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100065&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2020
    Goldsmith KC; Verschuur A; Morgenstern DA; van Eijkelenburg N; Federico SM; Fraser C; Forlenza CJ; Ziegler DS; Gerber NU; Khaw SL; Cooper TM; Flotho C; Prine BA; Salem AH; Unnebrink K; Tong B; Palenski TL; Place AE, 2020, 'The first report of pediatric patients with solid tumors treated with venetoclax.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, ELECTR NETWORK, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), ELECTR NETWORK, 29 May 2020 - 31 May 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000560368300242&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2020
    Haber M; Cowley MJ; Ekert P; Lau L; Mould E; Gifford A; Lock RB; Marshall GM; Norris MD; O'Brien T; Dong AKQ; Thomas D; Trahair T; Tucker K; Ziegler DS; Tyrrell V, 2020, 'Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer in Australia', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, Vol. 80, presented at AACR Annual Meeting, ELECTR NETWORK, 22 June 2020 - 24 June 2020, http://dx.doi.org/10.1158/1538-7445.AM2020-SY09-02
    Conference Abstracts | 2020
    Khan A; Gamble L; Pandher R; Burns MR; Mussai F; Norris M; Haber M; Tsoli M; Ziegler DS, 2020, 'COMBINATION OF ARGININE DEPLETION AND POLYAMINE INHIBITION AS AN ANTICANCER STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, Vol. 22, pp. 290 - 290, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100067&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2020
    Khan A; Gamble L; Pandher R; Burns MR; Mussai F; Norris M; Haber M; Tsoli M; Ziegler DS, 2020, 'DIPG-16. COMBINATION OF ARGININE DEPLETION AND POLYAMINE INHIBITION AS AN ANTICANCER STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii290 - iii290, http://dx.doi.org/10.1093/neuonc/noaa222.066
    Conference Abstracts | 2020
    Khan A; Gamble L; Upton D; Yu D; Ehteda A; Pandher R; Mayoh C; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2020, 'DIPG-15. POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii289 - iii290, http://dx.doi.org/10.1093/neuonc/noaa222.065
    Conference Papers | 2020
    Khan A; Gamble L; Upton D; Yu D; Ehteda A; Pandher R; Mayoh C; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2020, 'POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 289 - 290, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100066&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2020
    Khan S; Solano-Paez P; Suwal T; Al-Karmi S; Lu M; Ho B; Fouladi M; Leary S; Levy JMM; Lassaletta A; Rivas E; Reddy A; Gillespie GY; Gupta N; Yalon-Oren M; Amariglio L; Nakamura H; Wu K-S; Wong T-T; Ra Y-S; La Spina M; Emanuele PV; Massimi L; Buccoliero AM; Hansford JR; Grundy RG; Adamek D; Fangusaro J; Scharnhorst D; Johnston D; Lafay-Cousin L; Camelo-Piragua S; Kabbara N; Gajjar A; Boutarbouch M; Gil da Costa MJ; Hanson D; Wood P; Al-Hussaini M; Amayiri N; Wang Y; Catchpoole D; Michaud J; Bendel AE; Ellezam B; Gerber N; Plant A; Jeffery R; Dunham C; Moertel C; Walter A; Ziegler D; Dodgshun A; Gottardo N; Demir A; Ramanujachar R; Raabe E; Mary S; Dirks P; Taylor M; Eugene H; Lindsey H; Tihan T; Mette J; Dahl C; Low S; Smith A; Hazrati L-N; Kresak J; Gino S; Tan E; Morales A; Santa-Maria V; Hawkins C; Bartels U; Stephens D; Nobusawa S; Dufour C; Bourdeaut F; Andre N; Bouffet E; Huang A, 2020, 'TITLE: DEFINING THE CLINICAL AND PROGNOSTIC LANDSCAPE OF EMBRYONAL TUMORS WITH MULTI-LAYERED ROSETTES (ETMRS), A RARE BRAIN TUMOR REGISTRY (RBTC) STUDY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 328 - 328, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100226&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints | 2020
    Khan S; Solano-Paez P; Suwal T; Lu M; Al-Karmi S; Ho B; AlmeidaGonzalez CV; Stephens D; Dodgshun A; Shago M; Marrano P; Fonseca A; Hoffman LM; Leary S; Lindsay HB; Lassaletta A; Bendel AE; Moertel C; Morales A; Santa-Maria V; Lavarino C; Rivas E; Perreault S; Ellezam B; Jabado N; Oviedo A; Yalon-Oren M; Amariglio L; Toledano H; Loukides J; Van Meter TE; Nakamura H; Wong T-T; Wu K-S; Cheng C-J; Ra Y-S; La Spina M; Massimi L; Buccoliero AM; Reddy A; Li R; Gillespie GY; Adamek D; Fangusaro J; Scharnhorst D; Torkildson J; Johnston D; Michaud J; Lafay-Cousin L; Chan J; Van Landeghem F; Wilson B; Camelo-Piragua S; Kabbara N; Boutarbouch M; Hanson D; Jacobsen C; Wright K; Mulcahy Levy JM; Wang Y; Catchpoole D; Gerber N; Grotzer MA; Shen V; Plant A; Dunham C; da Costa MJG; Ramanujachar R; Raabe E; Rubens J; Philips J; Gupta N; Demir A; Dahl C; Jorgensen M; Hwang EI; Smith A; Tan E; Low S; Lu J-Q; Ho-Keung NG; Kresak JL; Gururangan S; Pomeroy SL; Sirachainan N; Hongeng S; Magimairajan V; Sinha R; Mushtaq N; Antony R; Sato M; Samuel D; Zapotocky M; Afzal S; Amayiri N; Al-Hussaini M; Walter A; Tihan T; Somers GR; Gajjar A; Wood P; Gottardo N; Cain JE; Downie PA; Branson H; Laughlin S; Ertl-Wagner B; Tsang DS; Ramaswamy V; Drake J; Kulkarni AV; Ziegler DS; Nobusawa S; Tabori U; Taylor MD; Ibrahim GM; Rutka JT; Dirks PB; Hazrati L-N; Grundy RG; Fouladi M; Padovani PL; Bourdeaut F; Hansford JR; Bartels U; Dufour C; Hawkins C; Andre N; Bouffet E; Huang A, 2020, Clinical phenotypes and prognostic features of ETMRs (Embryonal Tumor with Multi-layered Rosettes) a new CNS tumor entity: A Rare Brain Tumor Registry study, , http://dx.doi.org/10.1101/2020.08.12.20171801
    Conference Papers | 2020
    Lafay-Cousin L; Lane A; Schafer A; Saab R; Cheng S; Bandopadhayay P; Zaghloul M; El-Ayadi M; Dorris K; Packer R; Kilburn L; Minturn J; Dodgshun A; Parkin S; Garcia Lombardi M; Cohen K; Gass D; Goldman S; Sandler E; Warren K; Greiner R; Gottardo N; Dholaria H; Hassall T; Coven S; Hansford J; Samson Y; Leary S; Bartels U; Bouffet E; Ma J; Tinkle C; Monje-Deisseroth M; Fisher P; Tsui K; Ziegler D; Chintagumpala M; Gururangan S; Wagner L; Koschmann C; DeWire-Schottmiller M; Leach J; Jones B; Fuller C; Drissi R; Chaney B; Black K; Fouladi M; Strother D, 2020, 'RE-IRRADIATION OF DIPG: DATA FROM THE INTERNATIONAL DIPG REGISTRY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 301 - 302, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100117&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2020
    Lazow M; Fuller C; Lane A; DeWire M; Bandopadhayay P; Bartels U; Bouffet E; Cheng S; Cohen KJ; Cooney T; Coven S; Dholaria H; Diez B; Dorris K; El-Ayadi M; El-Sheikh A; Fisher P; Lombardi MG; Greiner R; Goldman S; Gottardo N; Gururangan S; Hansford J; Hassall T; Hawkins C; Kilburn L; Koschmann C; Leary S; Ma J; Minturn J; Monje M; Packer R; Samson Y; Sandler ES; Sevlever G; Tinkle C; Tsui K; Wagner L; Zaghloul M; Ziegler D; Chaney B; Black K; Asher A; Drissi R; Fouladi M; Jones B; Leach J, 2020, 'NON-DIPG PATIENTS ENROLLED IN THE INTERNATIONAL DIPG REGISTRY: HISTOPATHOLOGIC EVALUATION OF CENTRAL NEURO-IMAGING REVIEW', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, ELECTR NETWORK, pp. 154 - 154, presented at 25th Virtual Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology (SNO), ELECTR NETWORK, 19 November 2020 - 21 November 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000590061300645&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2020
    Lazow MA; Fuller C; Lane A; DeWire-Schottmiller MD; Bandopadhayay P; Bartels U; Bouffet E; Cheng S; Cohen KJ; Cooney TM; Coven SL; Dholaria H; Diez B; Dorris K; El-Ayadi M; El-Sheikh A; Fisher PG; Garcia Lombardi M; Greiner RJ; Goldman S; Gottardo N; Gururangan S; Hansford JR; Hassall T; Hawkins C; Kilburn L; Koschmann CJ; Leary SE; Ma J; Minturn JE; Monje-Deisseroth M; Packer RJ; Samson Y; Sandler ES; Sevlever G; Tinkle C; Tsui K; Wagner LM; Zaghloul M; Ziegler DS; Chaney B; Black K; Asher A; Drissi R; Fouladi M; Jones BV; Leach JL, 2020, 'NON-DIPG PATIENTS ENROLLED IN THE INTERNATIONAL DIPG REGISTRY: HISTOPATHOLOGIC EVALUATION OF CENTRAL NEURO-IMAGING REVIEW', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 295 - 296, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100093&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2020
    Michniewicz F; Saletta F; Rouen J; Ziegler D; Vittorio O, 2020, 'USING COPPER CHELATING AGENTS TO TARGET RECEPTOR TYROSINE KINASE SIGNALLING IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 303 - 303, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100125&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2020
    Mondal S; Wong M; Tee A; Ho N; Ziegler DS; Marshall GM; Liu PY; Dinger M; Liu T, 2020, 'The super-enhancer driven long noncoding RNA lncNB promotes neuroblastoma tumorigenesis', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, presented at AACR Annual Meeting, ELECTR NETWORK, 22 June 2020 - 24 June 2020, http://dx.doi.org/10.1158/1538-7445.AM2020-5721
    Conference Papers | 2020
    Robertson E; Wakefield C; Hetherington K; Ziegler D, 2020, 'Parents' Expectations and Experiences of a Precision Medicine Trial for High-Risk Paediatric Cancer', in PEDIATRIC BLOOD & CANCER, WILEY, pp. S47 - S47, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000581769200091&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2020
    Schulte JH; Moreno L; Ziegler DS; Marshall LV; Zwaan CM; Irwin M; Casanova M; Sabado C; Wulff B; Stegert M; Wang L; Hurtado FK; Branle F; Fischer M; Geoerger B, 2020, 'Final analysis of phase I study of ceritinib in pediatric patients with malignancies harboring activated anaplastic lymphoma kinase (ALK).', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, ELECTR NETWORK, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), ELECTR NETWORK, 29 May 2020 - 31 May 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000560368300223&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2020
    Sudhaman S; Morgenstern D; Chung J; Nobre L; Alsafwani N; Kelly J; Coblentz A; Edwards M; Bianchi V; Lipman T; Zhang C; Ercan A; Sambira L; Bendel A; Bielack S; Koustenis E; Blumenthal D; Bowers D; Broniscer A; Bronsema A; Carroll S; Chiaravalli S; Cole K; Constantini S; De Mola RL; Dunn G; Frojd C; Gass D; Gauvain K; George B; Hijiya N; Hoffman L; Knipstein J; Laetsch T; Larouche V; Lassaletta A; Luna-Fineman S; Issai VM; Mason G; Mason W; Massimino M; Mordechai O; Opocher E; Oren M; Osborn M; Reddy A; Remke M; Roy S; Sabel M; Samuel D; Schneider K; Sen S; Stearns D; Sumerauer D; Thomas G; Tomboc P; Van Damme A; Wierman M; Winer I; Yen L; Zapotocky M; Ziegler D; Zimmermann S; Dvir R; Rechavi G; Durno C; Aronson M; Taylor M; Dirks P; Pugh T; Shlien A; Hawkins C; Bouffet E; Tabori U, 2020, 'Favorable Outcome in Replication Repair Deficient Hypermutant Tumors to Immune Checkpoint Inhibition: An International RRD Consortium Registry Study', in PEDIATRIC BLOOD & CANCER, WILEY, pp. S19 - S20, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000581769200034&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2020
    Ung C; Tsoli M; Liu J; Cassano D; Upton D; Ehteda A; Mansfield F; Failes T; Kavallaris M; Arndt G; Vittorio O; Voliani V; Cirilo G; Ziegler DS, 2020, 'DDEL-12. NANOPARTICLE DELIVERY OF DOXORUBICIN FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii286 - iii286, http://dx.doi.org/10.1093/neuonc/noaa222.047
    Conference Papers | 2020
    Ung C; Tsoli M; Liu J; Cassano D; Upton D; Ehteda A; Mansfield F; Failes T; Kavallaris M; Arndt G; Vittorio O; Voliani V; Cirilo G; Ziegler DS, 2020, 'NANOPARTICLE DELIVERY OF DOXORUBICIN FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 286 - 286, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100048&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2020
    Upton D; Valvi S; Liu J; Yeung N; George S; Ung C; Khan A; Franshaw L; Ehteda A; Shen H; Orienti I; Farruggia G; Nath C; Reynolds P; Tsoli M; Ziegler D, 2020, 'DIPG-07. HIGH THROUGHPUT DRUG SCREENING IDENTIFIES POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGs)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii288 - iii288, http://dx.doi.org/10.1093/neuonc/noaa222.058
    Conference Papers | 2020
    Upton D; Valvi S; Liu J; Yeung N; George S; Ung C; Khan A; Franshaw L; Ehteda A; Shen H; Orienti I; Farruggia G; Nath C; Reynolds P; Tsoli M; Ziegler D, 2020, 'HIGH THROUGHPUT DRUG SCREENING IDENTIFIES POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGS)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 288 - 288, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100059&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Barahona P; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Haber M; Lock RB; Marshall GM; Mayoh C; Mould E; Nagabushan S; Norris M; O'Brien T; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Ziegler DS; Tyrrell VJ; Ekert P; Cowley MJ; Lau L; Quang D-AK, 2019, 'Zero Childhood Cancer (ZERO): A comprehensive precision medicine platform for children with highrisk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Montreal, Vol. 80, pp. 70 - 71, presented at AACR Special Conference on the Advances in Pediatric Cancer Research, CANADA, Montreal, 17 September 2019 - 20 September 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000551367400096&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Barahona P; Sherstyuk A; Cowley M; Ekert P; Kirk J; Dong-Anh K-Q; Kumar A; Lau L; Mayoh C; Marshall G; Moud E; O'Brien T; Pinese M; Thomas D; Tyrell V; Ziegler D; Haber M; Tucker K; Fuentes-Bolanos NA; Warby M, 2019, 'Prevalence and spectrum of germline mutations in children with high-risk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Montreal, Vol. 80, pp. 42 - 43, presented at AACR Special Conference on the Advances in Pediatric Cancer Research, CANADA, Montreal, 17 September 2019 - 20 September 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000551367400048&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2019
    Dahl N; Lane A; Bandopadhayay P; Minturn J; Dodgshun A; Parkin S; Shih C-S; Hassall T; Hansford J; Samson Y; Cai L; Leary S; Ma J; Bartels U; Hawkins C; Monje-Diesseroth M; Fisher P; Tsui K; Ziegler D; DeWire-Schottmiller M; Chaney B; Black K; Doughman R; Leach J; Jones B; Fuller C; Fouladi M; Hoffman L, 2019, 'CLINICAL, RADIOLOGICAL, AND HISTO-MOLECULAR CHARACTERISTICS OF DIFFUSE INTRINSIC PONTINE GLIOMA IN PATIENTS WHO SURVIVE LESS THAN 3 MONTHS FROM DIAGNOSIS: A REPORT FROM THE INTERNATIONAL DIPG REGISTRY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CA, San Francisco, pp. 76 - 77, presented at 5th Biennial Conference of the Society-for-Neuro-Oncology on Pediatric Neuro-Oncology Basic and Translational Research, CA, San Francisco, 03 May 2019 - 04 May 2019, http://dx.doi.org/10.1093/neuonc/noz036.057
    Conference Abstracts | 2019
    Duchatel R; Jackson E; Patabendige A; Cain J; Tsoli M; Monje M; Alvaro F; Ziegler D; Dun M, 2019, 'TARGETING PI3K USING THE BLOOD BRAIN BARRIER PENETRABLE INHIBITOR, GDC-0084, FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CA, San Francisco, Vol. 21, pp. 68 - 68, presented at 5th Biennial Conference of the Society-for-Neuro-Oncology on Pediatric Neuro-Oncology Basic and Translational Research, CA, San Francisco, 03 May 2019 - 04 May 2019, http://dx.doi.org/10.1093/neuonc/noz036.024
    Conference Abstracts | 2019
    Haber M; Gamble L; Xiao L; Pandher R; Somers K; Murray J; Khan A; Yu D; Franshaw L; Burns MR; Tsoli M; Ehteda A; Cesare A; O'Connor A; Mussai F; de Santo C; Cheng P; Korotchkina L; Gurova K; Tyrrell V; Mould E; Lau L; Dong AKQ; Mayoh C; Arndt G; Barahona P; Failes T; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Gifford A; Grebert-Wade D; Kamili A; Kumar A; Nagabushan S; O'Brien T; Strong P; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Xie J; Evans K; Lock R; Chernova OB; Henderson M; Gudkov AV; Ekert P; Cowley MJ; Marshall GM; Ziegler DS; Norris MD, 2019, 'Molecular targeted therapies and precision medicine for children with neuroblastoma and other refractory malignancies', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Montreal, Vol. 80, pp. 23 - 24, presented at AACR Special Conference on the Advances in Pediatric Cancer Research, CANADA, Montreal, 17 September 2019 - 20 September 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000551367400013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2019
    Li B; Vasiljevic A; Dufour C; Ho B; Hwang E; Gururangan S; Hansford J; Laquerriere A; Delisle M-B; Fangusaro J; Forest F; Sumihito N; Toledano H; Birks D; Fan X; Fouladi M; Gajjar A; Gauchotte G; Hoffman L; Jones C; Loussouarn D; Mokhtari K; Pomeroy S; Rousseau A; Somers G; Taylor M; Ziegler DS; Lu M; Hawkins C; Grundy R; Jouvet A; Bouffet E; Hill DA; Huang A, 2019, 'PINEOBLASTOMA SEGREGATES INTO MOLECULAR SUBTYPES WITH DISTINCT CLINICOPATHOLOGIC FEATURES: REPORT FROM THE RARE BRAIN TUMOUR CONSORTIUM', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, AZ, Phoenix, pp. 192 - 192, presented at 24th Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology (SNO) / 3rd SNO-SCIDOT Joint Conference on Therapeutic Delivery to the CNS, AZ, Phoenix, 20 November 2019 - 24 November 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000509478704105&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Mould EV; Lau L; Arndt G; Barahona P; Cowley MJ; Ekert P; Failes T; Fletcher J; Gifford A; Grebert-Wade D; Haber M; Kamili A; Kumar A; Lock RB; Marshall GM; Mayoh C; Norris M; O'Brien T; Quang DAK; Strong P; Sherstyuk A; Trahair T; Tsoli M; Tucker K; Warby M; Wong M; Xie J; Ziegler DS; Tyrrell V, 2019, 'Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-3111
    Conference Abstracts | 2019
    Quang DAK; Lau L; Cowley MJ; Ekert PG; Gifford AJ; Haber M; Lock R; Marshall G; Mayoh C; Mould E; Norris M; O'Brien T; Trahair T; Tyrrell V; Ziegler DS, 2019, 'Zero Childhood Cancer: A Comprehensive Precision Medicine Platform for Children and Adolescents with High-Risk Cancer', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 66, pp. S504 - S505, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488458005162&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Robertson E; Wakefield C; Cohn R; Robert B; Donoghoe M; Ziegler D; Fardell J; Mitchell R; O'Brien T, 2019, 'Delta: A Parent and Patient Decision Aid to Support Clinical Trial Decision-Making in Childhood Cancer', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 66, pp. S118 - S118, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488458001090&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Tsoli M; Lau L; Barahona P; Mayoh C; Failes T; Wong M; Sherstyuk A; Gifford AJ; Kumar A; Mould E; Ung C; Tolhurst O; Gopalakrishnan A; Grebert-Wade D; Strong P; Trebilcock P; Lock R; Tyrrell V; Trahair T; Tucker K; Warby M; Arndt G; Norris M; Haber M; Marshall G; O'Brien T; Dong AKQ; Cowley M; Ekert P; Ziegler DS, 2019, 'RESULTS OF THE ZERO CHILDHOOD CANCER INTEGRA-TM PRECISION MEDICINE PLATFORM FOR PAEDIATRIC HIGH-RISK BRAIN TUMOURS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CA, San Francisco, Vol. 21, pp. 118 - 118, presented at 5th Biennial Conference of the Society-for-Neuro-Oncology on Pediatric Neuro-Oncology Basic and Translational Research, CA, San Francisco, 03 May 2019 - 04 May 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000473243700229&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Tsoli M; Lau L; Barahona P; Mayoh C; Failes T; Wong M; Sherstyuk A; Gifford AJ; Kumar A; Mould E; Ung C; Tolhurst O; Gopalakrishnan A; Grebert-Wade D; Strong P; Trebilcock P; Lock R; Tyrrell V; Trahair T; Tucker K; Warby M; Arndt G; Norris M; Haber M; Marshall G; O’Brien T; Quang DAK; Cowley M; Ekert P; Ziegler DS, 2019, 'THER-23. RESULTS OF THE ZERO CHILDHOOD CANCER INTEGRATED PRECISION MEDICINE PLATFORM FOR PAEDIATRIC HIGH-RISK BRAIN TUMOURS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 21, pp. ii118 - ii118, http://dx.doi.org/10.1093/neuonc/noz036.228
    Conference Abstracts | 2019
    Vetsch J; Wakefield CE; Warby M; Tucker K; Duve E; Marshall G; Trahair T; O'Brien T; Lau L; Ziegler D, 2019, 'Families' and healthcare professionals' uncertainties in the era of cancer precision medicine: results from PRISM', in EUROPEAN JOURNAL OF HUMAN GENETICS, NATURE PUBLISHING GROUP, SWEDEN, Gothenburg, Vol. 27, pp. 1172 - 1172, presented at 52nd Conference of the European-Society-of-Human-Genetics (ESHG), SWEDEN, Gothenburg, 15 June 2019 - 18 June 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000489313900238&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Presentations | 2018
    Anazodo A; Hau P; Hovey E; Nowak A; Pfister S; Hesketh E; Bhadri V; Koh E; Ziegler D, 2018, 'Personalised targeted therapy for adolescent and young adult medulloblastoma patients.', presented at 3rd Global Adolescent and Young Adult Cancer Congress Program, Sheraton Grand Sydney, 04 December 2018 - 06 December 2018, https://www.eiseverywhere.com/ehome/312967
    Conference Papers | 2018
    Bartlett A; Cochrane A; Lane A; Yanez-Escorza N; Chaney B; Doughman R; DeWire-Schottmiller M; Goldman S; Warren K; Bandopadhayay P; Foreman N; Shih C-S; Minturn J; Bartels U; Packer R; Nazarian J; Hassall T; Samson Y; Monje-Deisseroth M; Fisher P; Wagner L; Koschmann C; Ziegler D; Kieran M; Hawkins C; White P; Dexheimer P; Hendershot J; Drissi R; Fuller C; Leach J; Jones B; Fouladi M, 2018, 'CLINICAL, RADIOLOGICAL, PATHOLOGICAL AND MOLECULAR CHARACTERISTICS OF CHILDREN < 3 YEARS WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): A REPORT FROM THE INTERNATIONAL DIPG REGISTRY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CO, Denver, pp. 63 - 63, presented at 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), CO, Denver, 30 June 2018 - 03 July 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000438339000165&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Ekert P; Wong M; Mould E; Gifford A; Norris M; Warby M; Trahair T; Tucker K; Ziegler D; Marshall G; O'Brien T; Haber M; Vanessa T; Cowley M, 2018, 'Zero Childhood Cancer: A Comprehensive Precision Medicine Platform for Children with High-Risk Cancer', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 65, pp. S643 - S644, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000445195005221&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Johnson A; Bye A; Ziegler D; Gifford A; Jacobsen E; Cohn R, 2018, 'CRAN-27. PAEDIATRIC EXTRAVENTRICULAR NEUROCYTOMA: A SERIES AND A RARE COMPLICATION', in Neuro-Oncology, Oxford University Press (OUP), Vol. 20, pp. i42 - i42, http://dx.doi.org/10.1093/neuonc/noy059.063
    Conference Abstracts | 2018
    Johnson A; Bye A; Ziegler D; Gifford A; Jacobsen E; Cohn R, 2018, 'PAEDIATRIC EXTRAVENTRICULAR NEUROCYTOMA: A SERIES AND A RARE COMPLICATION', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CO, Denver, Vol. 20, pp. 42 - 42, presented at 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), CO, Denver, 30 June 2018 - 03 July 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000438339000065&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Khan A; Gamble L; Yu D; Joshi S; Franshaw L; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2018, 'DIPG-01. TARGETING THE POLYAMINE PATHWAY AS A NOVEL THERAPEUTIC TREATMENT AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 20, pp. i49 - i49, http://dx.doi.org/10.1093/neuonc/noy059.095
    Conference Abstracts | 2018
    Khan A; Gamble L; Yu D; Joshi S; Franshaw L; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2018, 'TARGETING THE POLYAMINE PATHWAY AS A NOVEL THERAPEUTIC TREATMENT AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CO, Denver, Vol. 20, pp. 49 - 49, presented at 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), CO, Denver, 30 June 2018 - 03 July 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000438339000097&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Khan A; Tsoli M; Yu D; Joshi S; Gamble L; Franshaw L; Haber M; Ziegler DS, 2018, 'Targeting the polyamine pathway as a novel therapeutic treatment against diffuse intrinsic pontine glioma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, IL, Chicago, Vol. 78, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), IL, Chicago, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-4800
    Conference Papers | 2018
    Michaiel G; Strother D; Gottardo N; Bartels U; Coltin H; Eisenstat DD; Hukin J; Johnston DL; Wilson B; Zelcer S; Hansford JR; Wells O; Abdelbaki MS; Abu-Arja MH; Cole KA; Dhall G; Fisher PG; Hoffman L; Leary SES; Pickle EEO; Smiley NP; Smith A; Vinitsky A; Vitanza NA; Wright A; Yeo KK; Chow LML; Kirby M; Valvi S; Vanan MI; Wong G; Ziegler D; Bouffet E; Lafay-Cousin L, 2018, 'INTRACRANIAL GROWING TERATOMA SYNDROME (IGTS): AN INTERNATIONAL RETROSPECTIVE STUDY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CO, Denver, pp. 88 - 88, presented at 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), CO, Denver, 30 June 2018 - 03 July 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000438339000272&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Mokgwathi OL; Ziegler DS; Currie B; Tucker K; Gifford AJ, 2018, 'Pleuropulmonary blastoma – Case report of a rare tumour harbouring a DICER1 mutation', in Pathology, Elsevier BV, Vol. 50, pp. S144 - S144, http://dx.doi.org/10.1016/j.pathol.2017.11.062
    Conference Abstracts | 2018
    Mould E; Lau L; Arndt G; Barahona P; Cowley M; Ekert P; Failes T; Fletcher J; Gifford A; Haber M; Kamili A; Kumar A; Lock R; Marshall G; Mayoh C; Mead S; Norris M; O'Brien T; Pinese M; Dong AKQ; Trahair T; Tsoli M; Tucker K; Warby M; Wong M; Xie J; Ziegler D; Tyrrell V, 2018, 'Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, IL, Chicago, Vol. 78, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), IL, Chicago, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-LB-138
    Conference Abstracts | 2018
    Robertson E; Wakefield C; Cohn R; O'Brien T; Ziegler D; Fardell J, 2018, 'The development of Delta: a decision aid to help parents considering enroling their child in a paediatric oncology clinical trial', in PSYCHO-ONCOLOGY, WILEY, Vol. 27, pp. 10 - 10, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000426522700019&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Robertson EG; Mitchell R; Wakefield CE; Lewis P; Cousens N; Marshall GM; Russell SJ; Ziegler DS; Anazodo A; Trahair TN; Barbaric D; Cohn RJ; Alvaro F; O'Brien TA, 2018, 'Enrolment in early phase paediatric oncology clinical trials: the healthcare professionals’ perspective.', in PSYCHO-ONCOLOGY, WILEY, Hong Kong, Vol. 27, pp. 56 - 57, presented at International Psycho-Oncology Society, Hong Kong, 31 October 2018 - 02 November 2018, http://dx.doi.org/10.1111/jpc.14248
    Conference Papers | 2018
    Robertson EG; Mitchell R; Wakefield CE; Lewis P; Cousens N; Marshall GM; Russell SJ; Ziegler DS; Anazodo AC; Trahair TN; Barbaric D; Cohn RJ; Alvaro F; O'Brien T, 2018, 'Enrolment in early phase paediatric oncology clinical trials: the healthcare professionals’ perspective (poster)', in Enrolment in early phase paediatric oncology clinical trials: the healthcare professionals’ perspective (poster), Australian and New Zealand Children’s Haematology and Oncology Group (ANZCHOG), Sydney, presented at Australian and New Zealand Children’s Haematology and Oncology Group (ANZCHOG), Sydney, 14 June 2018 - 16 June 2018
    Conference Abstracts | 2018
    Tsoli M; Wadham C; Pinese M; Failes T; Joshi S; Mould E; Yin J; Gayevski V; Kumar A; Kaplan W; Ekert P; Franshaw L; Gifford A; Weber M; Rodriguez M; Mayoh C; Cohn R; Arndt G; Lock R; Tyrrell V; Norris M; Haber M; Lau L; Dong AKQ; Wong M; Trahair T; Marshall GM; Cowley MJ; Ziegler DS, 2018, 'Integrated genomics: drug screening and personalized xenograft development approach to identify precision treatments for aggressive pediatric brain tumors', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, IL, Chicago, Vol. 78, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), IL, Chicago, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-LB-137
    Conference Abstracts | 2018
    Vetsch J; Wakefield CE; Tucker K; Warby M; Techakesari P; Marshall G; Trahair TN; O'Brien T; Marron JM; Lau L; Tyrell V; Ziegler D, 2018, 'The PRISM-IMPACT study: What are the hopes and expectations of families and health care professionals enrolling in a personalised medicine trial for high risk childhood cancers?', in EUROPEAN JOURNAL OF HUMAN GENETICS, NATURE PUBLISHING GROUP, ITALY, Milan, Vol. 27, pp. 690 - 691, presented at 51st Conference of the European-Society-of-Human-Genetics (ESHG) in conjunction with the European Meeting on Psychosocial Aspects of Genetics (EMPAG), ITALY, Milan, 16 June 2018 - 19 June 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000489313105140&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Wakefield CE; Vetsch J; Tucker KM; Warby M; O'Brien T; Techakesari P; Glenn M; Trahair TN; Marron JM; Lau L; Tyrell V; Ziegler D, 2018, 'Families' and Healthcare Professionals' Hopes and Expectations Participating in a Precision Medicine Trial for Children with High-Risk Cancer: The PRISM-Impact Study', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 65, pp. S62 - S62, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000445195000120&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2018
    Xiao L; Murray J; Ehteda A; Somers C; Mayoh C; Gamble L; Pandher R; Tsoli M; Eden G; Allan S; Sarraf S; Kosciolek A; Ziegler D; Henderson M; Issaeva N; Gurova K; Gudkov A; Haber M; Norris M, 2018, 'Chromatin destabilization by CBL0137 and panobinostat leads to complete tumour regression of childhood neuroblastoma in immunocompetent transgenic mice', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, IRELAND, Dublin, pp. E25 - E25, presented at 30th EORTC-NCI-AACR Symposium, IRELAND, Dublin, 13 November 2018 - 16 November 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000461258600045&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Ziegler D; Tsoli M; Tyre V; Cohn R; Lau L; Cox M; Cowley M; Ekert P; Marshall G; Haber M, 2018, 'POTENT CLINICAL AND RADIOLOGICAL RESPONSE TO LAROTRECTINIB IN FIRST CASE OF TRK FUSION HIGH GRADE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CO, Denver, Vol. 20, pp. 67 - 67, presented at 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), CO, Denver, 30 June 2018 - 03 July 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000438339000180&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Ziegler D; Tsoli M; Tyrell V; Cohn R; Lau L; Cox M; Cowley M; Ekert P; Marshall G; Haber M, 2018, 'EAPH-09. POTENT CLINICAL AND RADIOLOGICAL RESPONSE TO LAROTRECTINIB IN FIRST CASE OF TRK FUSION HIGH GRADE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 20, pp. i67 - i67, http://dx.doi.org/10.1093/neuonc/noy059.178
    Conference Papers | 2017
    Burns MR; Fosnaugh K; Palfreyman MG; Gamble L; Murray J; Allan S; Eden G; Sarraf S; Norris M; Ziegler D; Haber M, 2017, 'AMX-513 polyamine depletion therapy inhibits tumor growth and reverses immunosuppression in cancers including MYC-driven neuroblastoma and pancreatic cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 01 April 2017 - 05 April 2017, http://dx.doi.org/10.1158/1538-7445.AM2017-2006
    Conference Abstracts | 2017
    Ehteda A; Kankean A; Chitranjan A; Tsoli M; Liu J; Shen H; Franshaw L; Joshi S; Chang C; Ager E; Ziegler DS, 2017, 'DIPG-09. TRX-E-009-1 IS A NOVEL AND A POTENT THERAPEUTIC AGENT FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv6 - iv6, http://dx.doi.org/10.1093/neuonc/nox083.024
    Conference Papers | 2017
    Ehteda A; Kankean A; Chitranjan A; Tsoli M; Liu J; Shen H; Franshaw L; Joshi S; Chang C; Ager E; Ziegler DS, 2017, 'TRX-E-009-1 IS A NOVEL AND A POTENT THERAPEUTIC AGENT FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, NY, New York, pp. 6 - 6, presented at 4th Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, NY, New York, 15 June 2017 - 16 June 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000402766800026&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2017
    Franshaw L; Chang C; Joshi S; Ehteda A; Tsoli M; Ziegler D, 2017, 'DIPG-07. INDUCING DNA LETHALITY THROUGH POLO-LIKE KINASE 1 INHIBITION: A NOVEL THERAPEUTIC APPROACH IN DIPG', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv6 - iv6, http://dx.doi.org/10.1093/neuonc/nox083.022
    Conference Papers | 2017
    Franshaw L; Chang C; Joshi S; Ehteda A; Tsoli M; Ziegler D, 2017, 'INDUCING DNA LETHALITY THROUGH POLO-LIKE KINASE 1 INHIBITION: A NOVEL THERAPEUTIC APPROACH IN DIPG', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, NY, New York, pp. 6 - 6, presented at 4th Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, NY, New York, 15 June 2017 - 16 June 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000402766800024&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2017
    Franshaw L; Tsoli M; Byrne J; Sivarajasingam S; Norris M; Marshall G; Ziegler D, 2017, 'TRTH-05. PREDICTORS OF SUCCESS OF PHASE 2 PAEDIATRIC ONCOLOGY CLINICAL TRIALS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv52 - iv52, http://dx.doi.org/10.1093/neuonc/nox083.217
    Conference Abstracts | 2017
    Lau L; Byrne J; Ekert PG; Failes T; Fellowes A; Fletcher J; Gifford A; Haber M; Kumar A; Lock R; Marshall G; McCowage GB; Mould E; Norris M; Trahair T; Tsoli M; Tyrrell V; Wadham C; Xie J; Ziegler DS, 2017, 'Pilot study of a comprehensive precision medicine platform for children with high-risk cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, Vol. 35, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 02 June 2017 - 06 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.10539
    Conference Abstracts | 2017
    Shen H; Chang C; Joshi S; Liu J; Tsoli M; Hau E; Ziegler D, 2017, 'DIPG-02. RADIOSENSITIVITY OF DIPG CELLS IS ENHANCED BY TARGETING GLUCOSE METABOLISM IN VITRO AND IN VIVO', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv5 - iv5, http://dx.doi.org/10.1093/neuonc/nox083.017
    Conference Papers | 2017
    Shen H; Chang C; Joshi S; Liu J; Tsoli M; Hau E; Ziegler D, 2017, 'RADIOSENSITIVITY OF DIPG CELLS IS ENHANCED BY TARGETING GLUCOSE METABOLISM IN VITRO AND IN VIVO', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, NY, New York, pp. 5 - 5, presented at 4th Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, NY, New York, 15 June 2017 - 16 June 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000402766800019&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2017
    Tsoli M; Lapin D; Franshaw L; Shen H; Liu J; Ziegler D, 2017, 'COMBINED TARGETING OF CALCIUM SIGNALLING AND RTK/PI3K PATHWAY IS A NOVEL THERAPEUTIC APPROACH AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, NY, New York, pp. 5 - 5, presented at 4th Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, NY, New York, 15 June 2017 - 16 June 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000402766800021&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2017
    Tsoli M; Lapin D; Franshaw L; Shen H; Liu J; Ziegler D, 2017, 'DIPG-04. COMBINED TARGETING OF CALCIUM SIGNALLING AND RTK/PI3K PATHWAY IS A NOVEL THERAPEUTIC APPROACH AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv5 - iv5, http://dx.doi.org/10.1093/neuonc/nox083.019
    Conference Abstracts | 2017
    Tsoli M; Yeung N; Valvi S; Joshi S; Franshaw L; Shen H; Liu J; Ziegler D, 2017, 'COMBINATION OF SYNTHETIC RETINOID FENRETINIDE WITH RECEPTOR TYROSINE KINASE INHIBITOR PONATINIB AS A POTENTIAL NEW APPROACH AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, NY, New York, Vol. 19, pp. 5 - 6, presented at 4th Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, NY, New York, 15 June 2017 - 16 June 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000402766800022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2017
    Tsoli M; Yeung N; Valvi S; Joshi S; Franshaw L; Shen H; Liu J; Ziegler D, 2017, 'DIPG-05. COMBINATION OF SYNTHETIC RETINOID FENRETINIDE WITH RECEPTOR TYROSINE KINASE INHIBITOR PONATINIB AS A POTENTIAL NEW APPROACH AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv5 - iv6, http://dx.doi.org/10.1093/neuonc/nox083.020
    Conference Papers | 2016
    Ehteda A; Tsoli M; Chitranjan A; Chang C; Simon S; Kankean A; Shen H; Liu J; Haber M; Gudkov A; Ziegler D, 2016, 'COMBINATION OF EPIGENETIC MODIFIERS CBL0137 AND PANOBINOSTAT IS HIGHLY POTENT IN VITRO AND IN VIVO FOR DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, ENGLAND, Liverpool, pp. 51 - 51, presented at 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), ENGLAND, Liverpool, 12 June 2016 - 15 June 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000379749000196&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Ehteda A; Tsoli M; Chitranjan A; Chang C; Simon S; Kankean A; Shen H; Liu J; Haber M; Gudkov A; Ziegler D, 2016, 'HG-20COMBINATION OF EPIGENETIC MODIFIERS CBL0137 AND PANOBINOSTAT IS HIGHLY POTENT IN VITRO AND IN VIVO FOR DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-oncology, Oxford University Press (OUP), Vol. 18, pp. iii51 - iii51, http://dx.doi.org/10.1093/neuonc/now073.17
    Conference Abstracts | 2016
    Fardell J; Donovan L; Wakefield C; Russell V; Mitchell R; O'Brien T; Ziegler D; Glenn M; Cohn R, 2016, 'Outcomes of Bereaved Parents Whose Child Did or Did not Participate in An Early Phase Clinical Trial', in PEDIATRIC BLOOD & CANCER, WILEY-BLACKWELL, Vol. 63, pp. S62 - S62, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000384818800579&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Robertson E; Fardell J; O'Brien T; Cohn R; Mitchell R; Drew D; Ziegler D; Marshall G; Wakefield C, 2016, 'Treatment Decision Making for Young People with Cancer and Their Parents', in PEDIATRIC BLOOD & CANCER, WILEY-BLACKWELL, Vol. 63, pp. S232 - S232, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000384818801393&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2016
    Shen H; Tsoli M; Chang C; Chitranjan A; Liu J; Hau E; Kankean A; Ehteda A; Franshaw L; Valvi S; Ziegler D, 2016, 'DICHLOROACETATE AND METFORMIN COMBINE TO MODULATE GLUCOSE METABOLISM AND POTENTLY SENSITISE DIPG CELLS TO RADIATION THERAPY', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, ENGLAND, Liverpool, pp. 48 - 48, presented at 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), ENGLAND, Liverpool, 12 June 2016 - 15 June 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000379749000182&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Shen H; Tsoli M; Chang C; Chitranjan A; Liu J; Hau E; Kankean A; Ehteda A; Franshaw L; Valvi S; Ziegler D, 2016, 'HG-04DICHLOROACETATE AND METFORMIN COMBINE TO MODULATE GLUCOSE METABOLISM AND POTENTLY SENSITISE DIPG CELLS TO RADIATION THERAPY', in Neuro-Oncology, Oxford University Press (OUP), Vol. 18, pp. iii48.3 - iii48, http://dx.doi.org/10.1093/neuonc/now073.03
    Conference Papers | 2016
    Tsoli M; Chang C; Shen H; Liu J; Chintranjan A; Franshaw L; Dilda P; Carcaboso AM; Hogg P; Ziegler D, 2016, 'COMBINED TARGETING OF MITOCHONDRIAL FUNCTION AND mTOR IS A POTENT NOVEL THERAPEUTIC APPROACH FOR DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, ENGLAND, Liverpool, pp. 51 - 51, presented at 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), ENGLAND, Liverpool, 12 June 2016 - 15 June 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000379749000195&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Tsoli M; Chang C; Shen H; Liu J; Chintranjan A; Franshaw L; Dilda P; Carcaboso AM; Hogg P; Ziegler D, 2016, 'HG-19COMBINED TARGETING OF MITOCHONDRIAL FUNCTION AND mTOR IS A POTENT NOVEL THERAPEUTIC APPROACH FOR DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 18, pp. iii51.3 - iii51, http://dx.doi.org/10.1093/neuonc/now073.16
    Conference Papers | 2016
    Valvi S; Tsoli M; Chitranjan A; Shen H; Chang C; Kankean A; Ehteda A; Franshaw L; Liu J; Ziegler D, 2016, 'FENRETINIDE TARGETS THE RTK-PI3K PATHWAY IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, ENGLAND, Liverpool, pp. 52 - 53, presented at 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), ENGLAND, Liverpool, 12 June 2016 - 15 June 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000379749000201&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Valvi S; Tsoli M; Chitranjan A; Shen H; Chang C; Kankean A; Ehteda A; Franshaw L; Liu J; Ziegler D, 2016, 'HG-25FENRETINIDE TARGETS THE RTK-PI3K PATHWAY IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 18, pp. iii52.5 - iii53, http://dx.doi.org/10.1093/neuonc/now073.22
    Conference Papers | 2015
    Carter DR; Murray J; Cheung BB; Kalla H; Gamble L; Tsang J; Sutton S; Koach J; Syed S; Gifford A; Issaeva N; Biktasova A; Atmadibrata B; Sun Y; Sokolowski N; Ling D; Kim PY; Webber H; Clark A; Ruhle M; Liu B; Oberthuer A; Fischer M; Byrne J; Saletta F; Purmal A; Ziegler D; Liu T; Gurova KV; Gudkov AV; Norris MD; Haber M; Marshall GM, 2015, 'MYCN and is a therapeutic target in neuroblastoma', in MOLECULAR CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, La Jolla, presented at AACR Special Conference on Myc - From Biology to Therapy, CA, La Jolla, 07 January 2015 - 10 January 2015, http://dx.doi.org/10.1158/1557-3125,MYC15-PRO9
    Conference Abstracts | 2015
    Haber M; Murray J; Gamble L; Carnegie-Clark A; Webber H; Ruhle M; Henderson MJ; Middlemass S; Carter D; Tsoli M; Ehteda A; Simon S; Oberthuer A; Fischer M; Gurova K; Burkhart C; Purmal A; Lock RB; Ziegler D; Marshall GM; Gudkov AV; Norris MD, 2015, 'The FACT histone chaperone complex is highly expressed in aggressive drug refractory childhood cancers and the anti-FACT compound CBL0137 represents a highly promising therapeutic approach in this setting', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, Vol. 75, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-1611
    Conference Abstracts | 2015
    Kankean A; Ehteda A; Chitranjan A; Tsoli M; Ager E; Ziegler D, 2015, 'BT-09 * TRILEXIUM INHIBITS THE EXPRESSION OF t-NOX AND IS A NOVEL, POTENTIALLY POTENT THERAPY FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 17, pp. iii5 - iii5, http://dx.doi.org/10.1093/neuonc/nov061.19
    Conference Papers | 2015
    Kankean A; Ehteda A; Chitranjan A; Tsoli M; Ager E; Ziegler D, 2015, 'TRILEXIUM INHIBITS THE EXPRESSION OF t-NOX AND IS A NOVEL, POTENTIALLY POTENT THERAPY FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CA, San Diego, pp. 5 - 5, presented at 3rd Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, CA, San Diego, 07 May 2015 - 08 May 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000361304800020&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Kankean A; Tsoli M; Tsang J; Chitranjan A; Maleki S; McDonald K; Ziegler D, 2015, 'HG-16 * THE ANTI-APOPTOTIC PROTEIN ARC IS OVER-EXPRESSED IN MALIGNANT GLIOMA AND CORRELATES WITH PATIENT OUTCOME', in Neuro-Oncology, Oxford University Press (OUP), Vol. 17, pp. iii14 - iii14, http://dx.doi.org/10.1093/neuonc/nov061.53
    Conference Papers | 2015
    Kankean A; Tsoli M; Tsang J; Chitranjan A; Maleki S; McDonald K; Ziegler D, 2015, 'THE ANTI-APOPTOTIC PROTEIN ARC IS OVER-EXPRESSED IN MALIGNANT GLIOMA AND CORRELATES WITH PATIENT OUTCOME', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CA, San Diego, pp. 14 - 14, presented at 3rd Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, CA, San Diego, 07 May 2015 - 08 May 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000361304800054&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2015
    Vedi A; Mitchell R; Oswald C; Marshall GM; Trahair T; Ziegler DS, 2015, 'Increased Use of Allogeneic Transplant in CR2 Improves the Outcome for Children with Acute Myeloid Leukaemia', in BLOOD, AMER SOC HEMATOLOGY, FL, Orlando, presented at 57th Annual Meeting of the American-Society-of-Hematology, FL, Orlando, 05 December 2015 - 08 December 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000368020102033&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2015
    Wadham C; Saletta F; Byrne JA; Trahair T; Ziegler DS; McCowage G; Marshall G; Haber M; Norris M, 2015, 'Molecular profiling of relapsed childhood cancer', in CLINICAL CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, UT, Salt Lake, presented at Meeting of the American-Association-for-Cancer-Research (AACR) Precision Medicine Series - Integrating Clinical Genomics and Cancer Therapy, UT, Salt Lake, 13 June 2015 - 16 June 2015, http://dx.doi.org/10.1158/1557-3265.PMSCLINGEN15-51
    Conference Papers | 2014
    Haber M; Murray J; Gamble L; Carnegie-Clark A; Webber H; Ruhle M; Carter D; Oberthur A; Fischer M; Ziegler D; Marshall GM; Gurova K; Burkhart C; Purmal A; Gudkov AV; Norris MD, 2014, 'CBL0137, a novel NFkB suppressor and p53 activator, is highly effective in pre-clinical models of neuroblastoma', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, SPAIN, European Org Res & Treatment Canc, Barcelona, pp. 135 - 135, presented at 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, SPAIN, European Org Res & Treatment Canc, Barcelona, 18 November 2014 - 21 November 2014, http://dx.doi.org/10.1016/S0959-8049(14)70548-9
    Conference Papers | 2014
    Tsoli M; Vanniasinghe A; Luk P; Dilda P; Haber M; Hogg P; Ziegler D, 2014, 'TARGETING MITOCHONDRIA AND CELL METABOLISM AS A NOVEL THERAPEUTIC APPROACH IN THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, SINGAPORE, Singapore, pp. 47 - 47, presented at 16th International Symposium on Pediatric Neuro-Oncology (ISPNO), SINGAPORE, Singapore, 28 June 2014 - 02 July 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000337924200179&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2013
    Mitic G; Tsoli M; Ziegler DS; Kavallaris M, 2013, 'beta III-tubulin in glioblastoma: An emerging multifactorial survival factor role in chemotherapy response and tumor formation.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, Vol. 73, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-3431
    Conference Papers | 2013
    Norris MD; Gamble LD; Murray J; Purqato S; Miiazzo G; Ashton LJ; Oberthuer A; London WB; Hogarty MD; Fischer M; Ziegler D; Marshall GM; Perini G; Haber M, 2013, 'MYCN coordinately regulates the entire polyamine gene pathway to drive polyamine biosynthesis in neuroblastoma, with expression of every synthetic and catabolic polyamine pathway gene being highly prognostic of clinical outcome', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-3808
    Conference Papers | 2013
    Tsoli M; Luk P; Dilda P; Hogg P; Haber M; Ziegler D, 2013, 'TARGETING MITOCHONDRIA AND METABOLISM AS A NOVEL THERAPEUTIC APPROACH IN THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, FL, Fort Lauderdale, pp. 21 - 21, presented at 2nd Annual Pediatric Neuro-Oncology Basic and Translational Research Conference, FL, Fort Lauderdale, 16 May 2013 - 17 May 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000318570500078&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2012
    Lee H; Ziegler D, 2012, 'LONGER DURATION OF SYMPTOMS AT DIAGNOSIS IS AN INDEPENDENT PROGNOSTIC FACTOR IN PEDIATRIC DIFFUSE PONTINE INTRINSIC GLIOMAS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CANADA, Toronto, pp. 29 - 29, presented at 15th International Symposium on Pediatric Neuro-Oncology (ISPNO), CANADA, Toronto, 24 June 2012 - 27 June 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308394400109&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2012
    Mitic G; Tsoli M; Ziegler DS; Kavallaris M, 2012, 'beta III-TUBULIN AND GLIOBLASTOMA: ROLE IN DRUG RESISTANCE AND TUMOURIGENESIS', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, Vol. 8, pp. 303 - 304, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310544400264&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2011
    Mateos M; O'Brien TA; Gabriel M; Oswald C; Cohn RJ; Russell S; Ziegler DS; Barbaric D; Vowels M; Maurice L; Senner A; Marshall G; Trahair T, 2011, 'IMPROVED SURVIVAL FOLLOWING ALLOGENEIC HAEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT) FOR PAEDIATRIC ACUTE LYMPHOBLASTIC LEUKAEMIA (ALL): A RETROSPECTIVE REVIEW FROM 1984-2009', in PEDIATRIC BLOOD & CANCER, WILEY PERIODICALS, INC, pp. 817 - 817, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000295239600446&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2010
    Smee RI; Cohn R; Ziegler D; Kwok B; Johnston H; Bye A; Andrews I; Stening W, 2010, 'A RETROSPECTIVE REVIEW OF CHILDREN TREATED AT THE SYDNEY CHILDREN'S HOSPITAL/PRINCE OF WALES HOSPITAL', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, AUSTRIA, Vienna, pp. II69 - II70, presented at 14th International Symposium on Pediatric Neuro-Oncology, AUSTRIA, Vienna, 20 June 2010 - 23 June 2010, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000278817700314&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2004
    Ziegler DS; Cohn RJ; McCowage G; Alvaro F; Oswald C; Mrongovius R; White F, 2004, 'Efficacy of high-dose cyclophosphamide with etoposide and vinchistine ("VETOPEC") in very high-risk paediatric brain tumours', in NEURO-ONCOLOGY, DUKE UNIV PRESS, MA, Boston, pp. 469 - 469, presented at 11th International Symposium on Pediatric Neuro-Oncology, MA, Boston, 13 June 2004 - 16 June 2004, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000224332400610&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints |
    Crothers AL; Haeusler GM; Slavin MA; Babl FE; Mechinaud F; Phillips R; Tapp H; Padhye B; Ziegler DS; Clark J; Walwyn T; Super L; Alvaro F; Thursky K; Lourenco RDA, Examining Health-Related Quality of Life in Pediatric Cancer Patients with Febrile Neutropenia: Factors Predicting for Poor Recovery in Children and the Parents, , http://dx.doi.org/10.2139/ssrn.3860325

Prof Ziegler's research focused on the preclinical and clinical development of novel therapies for paediatric cancer including high risk brain tumours. Prof Ziegler has established an Australian translational research program to develop novel therapies for children with cancer, and has led several national and international early phase clinical trials. He is chair of a national study of precision medicine for high risk childhood cancers through the ZERO childhood cancer program.