Conjoint Associate Professor

Associate Professor David Simon Ziegler

MBBS (Hons 1), BSc(Med), FRACP, MD(Res)

Medicine & Health
Sch Women's&Children's Health

 A/Prof David Ziegler is a Senior Staff Specialist in the Kids Cancer Centre at Sydney Children’s Hospital and has expertise in neuro-oncology and early phase clinical trials.  A/Prof Ziegler completed his clinical training in paediatric haematology and oncology at Sydney Children’s Hospital.  From 2005-2007 he was a Fulbright Scholar at the Dana Farber Cancer Institute, Harvard Medical School and Children’s Hospital Boston.  He is a Conjoint Associate Professor at the University of New South Wales and a Group Leader at the Children’s Cancer Institute (CCI), where his preclinical research focuses on novel therapies for childhood brain tumours. He is deputy director of the Kids Cancer Alliance – a translational research program supported by the Cancer Institute NSW.

Phone
+61-2-93821730

Publications

  • Journal articles | 2021
    Associate Professor David Simon Ziegler
    Durno C; Ercan AB; Bianchi V; Edwards M; Aronson M; Galati M; Atenafu EG; Abebe-Campino G; Al-Battashi A; Alharbi M; Azad VF; Baris HN; Basel D; Bedgood R; Bendel A; Ben-Shachar S; Blumenthal DT; Blundell M; Bornhorst M; Bronsema A; Cairney E; Rhode S; Caspi S; Chamdin A; Chiaravalli S; Constantini S; Crooks B; Das A; Dvir R; Farah R; Foulkes WD; Frenkel Z; Gallinger B; Gardner S; Gass D; Ghalibafian M; Gilpin C; Goldberg Y; Goudie C; Hamid SA; Hampel H; Hansford JR; Harlos C; Hijiya N; Hsu S; Kamihara J; Kebudi R; Knipstein J; Koschmann C; Kratz C; Larouche V; Lassaletta A; Lindhorst S; Ling SC; Link MP; Loret De Mola R; Luiten R; Lurye M; Maciaszek JL; MagimairajanIssai V; Maher OM; Massimino M; McGee RB; Mushtaq N; Mason G; Newmark M; Nicholas G; Nichols KE; Nicolaides T; Opocher E; Osborn M; Oshrine B; Pearlman R; Pettee D; Rapp J; Rashid M; Reddy A; Reichman L; Remke M; Robbins G; Roy S; Sabel M; Samuel D; Scheers I; Schneider KW; Sen S; Stearns D; Sumerauer D; Swallow C; Taylor L; Thomas G; Toledano H; Tomboc P; Van Damme A; Winer I; Yalon M; Yen LY; Zapotocky M; Zelcer S; Ziegler DS; Zimmermann S; Hawkins C; Malkin D; Bouffet E; Villani A; Tabori U, 2021, 'Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance.', J Clin Oncol, pp. JCO2002636, http://dx.doi.org/10.1200/JCO.20.02636
    Journal articles | 2021
    Associate Professor David Simon Ziegler
    Ryan AL; Burns C; Gupta AK; Samarasekera R; Ziegler DS; Kirby ML; Alvaro F; Downie P; Laughton SJ; Cross S; Hassall T; McCowage GB; Hansford JR; Kotecha RS; Gottardo NG, 2021, 'Malignant Melanoma in Children and Adolescents Treated in Pediatric Oncology Centers: An Australian and New Zealand Children’s Oncology Group (ANZCHOG) Study', Frontiers in Oncology, vol. 11, pp. 660172, http://dx.doi.org/10.3389/fonc.2021.660172
    Journal articles | 2021
    Associate Professor David Simon Ziegler
    Michniewicz F; Saletta F; Rouaen JRC; Hewavisenti RV; Mercatelli D; Cirillo G; Giorgi FM; Trahair T; Ziegler D; Vittorio O, 2021, 'Copper: An Intracellular Achilles' Heel Allowing the Targeting of Epigenetics, Kinase Pathways, and Cell Metabolism in Cancer Therapeutics.', ChemMedChem, http://dx.doi.org/10.1002/cmdc.202100172
    Journal articles | 2021
    Associate Professor David Simon Ziegler
    Gamble LD; Purgato S; Henderson MJ; Di Giacomo S; Russell AJ; Pigini P; Murray J; Valli E; Milazzo G; Giorgi FM; Cowley M; Ashton LJ; Bhalshankar J; Schleiermacher G; Rihani A; Van Maerken T; Vandesompele J; Speleman F; Versteeg R; Koster J; Eggert A; Noguera R; Stallings RL; Tonini GP; Fong K; Vaksman Z; Diskin SJ; Maris JM; London WB; Marshall GM; Ziegler DS; Hogarty MD; Perini G; Norris MD; Haber M, 2021, 'A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma', Cancers, vol. 13, http://dx.doi.org/10.3390/cancers13081807
    Journal articles | 2021
    Associate Professor David Simon Ziegler
    Janjua TI; Rewatkar P; Ahmed-Cox A; Saeed I; Mansfeld FM; Kulshreshtha R; Kumeria T; Ziegler DS; Kavallaris M; Mazzieri R; Popat A, 2021, 'Frontiers in the treatment of glioblastoma: Past, present and emerging', Advanced Drug Delivery Reviews, vol. 171, pp. 108 - 138, http://dx.doi.org/10.1016/j.addr.2021.01.012
    Journal articles | 2021
    Associate Professor David Simon Ziegler
    Xie J; Kumar A; Dolman MEM; Mayoh C; Khuong-Quang D-A; Cadiz R; Wong-Erasmus M; Mould EVA; Grebert-Wade D; Barahona P; Kamili A; Tsoli M; Failes TW; Chow S-O; Bhatia K; Marshall GM; Ziegler DS; Haber M; Lock RB; Tyrrell V; Lau L; Athanasatos P; Gifford AJ, 2021, 'The important role of routine cytopathology in pediatric precision oncology', CANCER CYTOPATHOLOGY, http://dx.doi.org/10.1002/cncy.22448
    Journal articles | 2021
    Associate Professor David Simon Ziegler
    Haeusler GM; Lourenco RDA; Clark H; Thursky KA; Slavin MA; Babl FE; Mechinaud F; Alvaro F; Clark J; Padhye B; Phillips M; Super L; Tapp H; Walwyn T; Ziegler D; Phillips R; Worth LJ, 2021, 'Diagnostic Yield of Initial and Consecutive Blood Cultures in Children With Cancer and Febrile Neutropenia', JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY, vol. 10, pp. 125 - 130, http://dx.doi.org/10.1093/jpids/piaa029
    Journal articles | 2021
    Associate Professor David Simon Ziegler
    Ehteda A; Simon S; Franshaw L; Giorgi FM; Liu J; Joshi S; Rouaen JRC; Pang CNI; Pandher R; Mayoh C; Tang Y; Khan A; Ung C; Tolhurst O; Kankean A; Hayden E; Lehmann R; Shen S; Gopalakrishnan A; Trebilcock P; Gurova K; Gudkov AV; Norris MD; Haber M; Vittorio O; Tsoli M; Ziegler DS, 2021, 'Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG', Cell Reports, vol. 35, pp. 108994 - 108994, http://dx.doi.org/10.1016/j.celrep.2021.108994
    Journal articles | 2021
    Associate Professor David Simon Ziegler
    Chung J; Maruvka YE; Sudhaman S; Kelly J; Haradhvala NJ; Bianchi V; Edwards M; Forster VJ; Nunes NM; Galati MA; Komosa M; Deshmukh S; Cabric V; Davidson S; Zatzman M; Light N; Hayes R; Brunga L; Anderson ND; Ho B; Hodel KP; Siddaway R; Morrissy AS; Bowers DC; Larouche V; Bronsema A; Osborn M; Cole KA; Opocher E; Mason G; Thomas GA; George B; Ziegler DS; Lindhorst S; Vanan M; Yalon-Oren M; Reddy AT; Massimino M; Tomboc P; Van Damme A; Lossos A; Durno C; Aronson M; Morgenstern DA; Bouffet E; Huang A; Taylor MD; Villani A; Malkin D; Hawkins CE; Pursell ZF; Shlien A; Kunkel TA; Getz G; Tabori U, 2021, 'DNA polymerase and mismatch repair exert distinct microsatellite instability signatures in normal and malignant human cells', Cancer Discovery, vol. 11, pp. 1176 - 1191, http://dx.doi.org/10.1158/2159-8290.CD-20-0790
    Journal articles | 2021
    Associate Professor David Simon Ziegler
    Ung C; Tsoli M; Liu J; Cassano D; Pocoví-Martínez S; Upton DH; Ehteda A; Mansfeld FM; Failes TW; Farfalla A; Katsinas C; Kavallaris M; Arndt GM; Vittorio O; Cirillo G; Voliani V; Ziegler DS, 2021, 'Doxorubicin-loaded gold nanoarchitectures as a therapeutic strategy against diffuse intrinsic pontine glioma', Cancers, vol. 13, pp. 1 - 20, http://dx.doi.org/10.3390/cancers13061278
    Journal articles | 2021
    Associate Professor David Simon Ziegler
    Himes RW; Chiou EH; Queliza K; Shouval DS; Somech R; Agarwal S; Jajoo K; Ziegler DS; Kratz CP; Huang J; Lucas TL; Myers KC; Nelson AS; DiNardo CD; Alter BP; Giri N; Khincha PP; McReynolds LJ; Dufour C; Pierri F; Goldman FD; Sherif Y; Savage SA; Miloh T; Bertuch AA, 2021, 'Gastrointestinal Hemorrhage: A Manifestation of the Telomere Biology Disorders', Journal of Pediatrics, vol. 230, pp. 55 - 61.e4, http://dx.doi.org/10.1016/j.jpeds.2020.09.038
    Journal articles | 2021
    Associate Professor David Simon Ziegler
    Nagabushan S; Lau LMS; Barahona P; Wong M; Sherstyuk A; Marshall GM; Tyrrell V; Wegner EA; Ekert PG; Cowley MJ; Mayoh C; Trahair TN; Crowe P; Anazodo A; Ziegler DS, 2021, 'Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor', NPJ PRECISION ONCOLOGY, vol. 5, http://dx.doi.org/10.1038/s41698-021-00145-8
    Journal articles | 2021
    Associate Professor David Simon Ziegler
    Khan A; Gamble LD; Upton DH; Ung C; Yu DMT; Ehteda A; Pandher R; Mayoh C; Hébert S; Jabado N; Kleinman CL; Burns MR; Norris MD; Haber M; Tsoli M; Ziegler DS, 2021, 'Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas', Nature Communications, vol. 12, pp. 971, http://dx.doi.org/10.1038/s41467-021-20896-z
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Wood P; Desai J; Waldeck K; Cain J; Gottardo N; Strong R; Kinross K; Carr M; Jones J; Wong L; Ziegler D; Hansford J; Michael M; Ashley D, 2020, 'ATRT-08. A PHASE II STUDY OF CONTINUOUS LOW DOSE PANOBINOSTAT IN PAEDIATRIC PATIENTS WITH MALIGNANT RHABDOID TUMORS/ATYPICAL TERATOID RHABDOID TUMORS', Neuro-Oncology, vol. 22, pp. iii277 - iii277, http://dx.doi.org/10.1093/neuonc/noaa222.008
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Perreault S; Doz F; Drilon A; Geoerger B; Boni V; Chisholm J; Dubois SG; Grilley-Olson JE; Hong DS; Italiano A; Kang H; Nysom K; Øra I; Owens C; Schulte JH; Tahara M; Ziegler D; Ellezam B; Reeves JA; Fellous M; De La Cuesta E; Laetsch TW; van Tilburg CM, 2020, 'CTNI-67. EFFICACY AND SAFETY OF LAROTRECTINIB IN PATIENTS WITH TROPOMYOSIN RECEPTOR KINASE (TRK) FUSION PRIMARY CENTRAL NERVOUS SYSTEM (CNS) TUMORS: AN EXPANDED DATASET', Neuro-Oncology, vol. 22, pp. ii58 - ii58, http://dx.doi.org/10.1093/neuonc/noaa215.233
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Schulte JH; Moreno L; Ziegler DS; Marshall LV; Zwaan CM; Irwin M; Casanova M; Sabado C; Wulff B; Stegert M; Wang L; Hurtado FK; Branle F; Fischer M; Geoerger B, 2020, 'Final analysis of phase I study of ceritinib in pediatric patients with malignancies harboring activated anaplastic lymphoma kinase (ALK).', Journal of Clinical Oncology, vol. 38, pp. 10505 - 10505, http://dx.doi.org/10.1200/jco.2020.38.15_suppl.10505
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Goldsmith KC; Verschuur A; Morgenstern DA; van Eijkelenburg N; Federico SM; Fraser C; Forlenza CJ; Ziegler DS; Gerber NU; Khaw SL; Cooper TM; Flotho C; Prine BA; Salem AH; Unnebrink K; Tong B; Palenski TL; Place AE, 2020, 'The first report of pediatric patients with solid tumors treated with venetoclax.', Journal of Clinical Oncology, vol. 38, pp. 10524 - 10524, http://dx.doi.org/10.1200/jco.2020.38.15_suppl.10524
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Michniewicz F; Saletta F; Rouen J; Ziegler D; Vittorio O, 2020, 'DIPG-83. USING COPPER CHELATING AGENTS TO TARGET RECEPTOR TYROSINE KINASE SIGNALLING IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', Neuro-Oncology, vol. 22, pp. iii303 - iii303, http://dx.doi.org/10.1093/neuonc/noaa222.124
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Goto H; Geoerger B; DuBois SG; Grilley-Olson JE; van Tilburg CM; Schulte J; Kang HJ; Tahara M; Boni V; Perreault S; Capra M; Reeves JA; Brega N; Childs BH; Laetsch TW; Ziegler DS; Doz F, 2020, 'EPCT-08. ACTIVITY OF LAROTRECTINIB IN PEDIATRIC TROPOMYOSIN RECEPTOR KINASE (TRK) FUSION CANCER PATIENTS WITH PRIMARY CENTRAL NERVOUS SYSTEM (CNS) TUMORS', Neuro-Oncology, vol. 22, pp. iii305 - iii305, http://dx.doi.org/10.1093/neuonc/noaa222.132
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Lazow MA; Fuller C; Lane A; DeWire-Schottmiller MD; Bandopadhayay P; Bartels U; Bouffet E; Cheng S; Cohen KJ; Cooney TM; Coven SL; Dholaria H; Diez B; Dorris K; El-Ayadi M; El-Sheikh A; Fisher PG; Lombardi MG; Greiner RJ; Goldman S; Gottardo N; Gururangan S; Hansford JR; Hassall T; Hawkins C; Kilburn L; Koschmann CJ; Leary SE; Ma J; Minturn JE; Monje-Deisseroth M; Packer RJ; Samson Y; Sandler ES; Sevlever G; Tinkle C; Tsui K; Wagner LM; Zaghloul M; Ziegler DS; Chaney B; Black K; Asher A; Drissi R; Fouladi M; Jones BV; Leach JL, 2020, 'DIPG-46. NON-DIPG PATIENTS ENROLLED IN THE INTERNATIONAL DIPG REGISTRY: HISTOPATHOLOGIC EVALUATION OF CENTRAL NEURO-IMAGING REVIEW', Neuro-Oncology, vol. 22, pp. iii295 - iii296, http://dx.doi.org/10.1093/neuonc/noaa222.092
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Hanson D; Andre N; Chi S; Filbin M; Fisher M; Hoffman L; Khatib Z; Kool M; Narendran A; Pizer B; Slavc I; Vogel T; Ziegler D; Kieran M, 2020, 'ETMR-08. INTERNATIONAL CONSENSUS PROTOCOL FOR EMBRYONAL TUMOR WITH MULTILAYER ROSETTES', Neuro-Oncology, vol. 22, pp. iii324 - iii324, http://dx.doi.org/10.1093/neuonc/noaa222.212
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    McGill BC; Wakefield CE; Hetherington K; Munro LJ; Warby M; Lau L; Tyrrell V; Ziegler DS; O’brien TA; Marshall GM; Malkin D; Hansford JR; Tucker KM; Vetsch J, 2020, '“Balancing Expectations with Actual Realities”: Conversations with Clinicians and Scientists in the First Year of a High-Risk Childhood Cancer Precision Medicine Trial', Journal of Personalized Medicine, vol. 10, http://dx.doi.org/10.3390/jpm10010009
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Clarke M; Mackay A; Ismer B; Pickles JC; Tatevossian RG; Newman S; Bale TA; Stoler I; Izquierdo E; Temelso S; Carvalho DM; Molinari V; Burford A; Howell L; Virasami A; Fairchild AR; Avery A; Chalker J; Kristiansen M; Haupfear K; Dalton JD; Orisme W; Wen J; Hubank M; Kurian KM; Rowe C; Maybury M; Crosier S; Knipstein J; Schüller U; Kordes U; Kram DE; Snuderl M; Bridges L; Martin AJ; Doey LJ; Al-Sarraj S; Chandler C; Zebian B; Cairns C; Natrajan R; Boult JKR; Robinson SP; Sill M; Dunkel IJ; Gilheeney SW; Rosenblum MK; Hughes D; Proszek PZ; Macdonald TJ; Preusser M; Haberler C; Slavc I; Packer R; Ng HK; Caspi S; Popović M; Kotnik BF; Wood MD; Baird L; Davare MA; Solomon DA; Olsen TK; Brandal P; Farrell M; Cryan JB; Capra M; Karremann M; Schittenhelm J; Schuhmann MU; Ebinger M; Dinjens WNM; Kerl K; Hettmer S; Pietsch T; Andreiuolo F; Driever PH; Korshunov A; Hiddingh L; Worst BC; Sturm D; Zuckermann M; Witt O; Bloom T; Mitchell C; Miele E; Colafati GS; Diomedi-Camassei F; Bailey S; Moore AS; Hassall TEG; Lowis SP; Tsoli M; Cowley MJ; Ziegler DS; Karajannis MA; Aquilina K; Hargrave DR; Carceller F; Marshall LV, 2020, 'Infant high-grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes', Cancer Discovery, vol. 10, pp. 942 - 963, http://dx.doi.org/10.1158/2159-8290.CD-19-1030
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Dodgshun AJ; Fukuoka K; Edwards M; Bianchi VJ; Das A; Sexton-Oates A; Larouche V; Vanan MI; Lindhorst S; Yalon M; Mason G; Crooks B; Constantini S; Massimino M; Chiaravalli S; Ramdas J; Mason W; Ashraf S; Farah R; Van Damme A; Opocher E; Hamid SA; Ziegler DS; Samuel D; Cole KA; Tomboc P; Stearns D; Thomas GA; Lossos A; Sullivan M; Hansford JR; Mackay A; Jones C; Jones DTW; Ramaswamy V; Hawkins C; Bouffet E; Tabori U, 2020, 'Germline-driven replication repair-deficient high-grade gliomas exhibit unique hypomethylation patterns', Acta Neuropathologica, vol. 140, pp. 765 - 776, http://dx.doi.org/10.1007/s00401-020-02209-8
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Burke MJ; Kostadinov R; Sposto R; Gore L; Kelley SM; Rabik C; Trepel JB; Lee MJ; Yuno A; Lee S; Bhojwani D; Jeha S; Chang BH; Sulis ML; Hermiston ML; Gaynon P; Huynh V; Verma A; Gardner R; Heym KM; Dennis RM; Ziegler DS; Laetsch TW; Oesterheld JE; Dubois SG; Pollard JA; Glade-Bender J; Cooper TM; Kaplan JA; Farooqi MS; Yoo B; Guest E; Wayne AS; Brown PA, 2020, 'Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study', Clinical Cancer Research, vol. 26, pp. 2297 - 2307, http://dx.doi.org/10.1158/1078-0432.CCR-19-1251
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Wong M; Mayoh C; Lau LMS; Khuong-Quang DA; Pinese M; Kumar A; Barahona P; Wilkie EE; Sullivan P; Bowen-James R; Syed M; Martincorena I; Abascal F; Sherstyuk A; Bolanos NA; Baber J; Priestley P; Dolman MEM; Fleuren EDG; Gauthier ME; Mould EVA; Gayevskiy V; Gifford AJ; Grebert-Wade D; Strong PA; Manouvrier E; Warby M; Thomas DM; Kirk J; Tucker K; O’Brien T; Alvaro F; McCowage GB; Dalla-Pozza L; Gottardo NG; Tapp H; Wood P; Khaw SL; Hansford JR; Moore AS; Norris MD; Trahair TN; Lock RB; Tyrrell V; Haber M; Marshall GM; Ziegler DS; Ekert PG; Cowley MJ, 2020, 'Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer', Nature Medicine, vol. 26, pp. 1742 - 1753, http://dx.doi.org/10.1038/s41591-020-1072-4
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Li BK; Vasiljevic A; Dufour C; Yao F; Ho BLB; Lu M; Hwang EI; Gururangan S; Hansford JR; Fouladi M; Nobusawa S; Laquerriere A; Delisle MB; Fangusaro J; Forest F; Toledano H; Solano-Paez P; Leary S; Birks D; Hoffman LM; Szathmari A; Faure-Conter C; Fan X; Catchpoole D; Zhou L; Schultz KAP; Ichimura K; Gauchotte G; Jabado N; Jones C; Loussouarn D; Mokhtari K; Rousseau A; Ziegler DS; Tanaka S; Pomeroy SL; Gajjar A; Ramaswamy V; Hawkins C; Grundy RG; Hill DA; Bouffet E; Huang A; Jouvet A, 2020, 'Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain Tumor Consortium registry study', Acta Neuropathologica, vol. 139, pp. 223 - 241, http://dx.doi.org/10.1007/s00401-019-02111-y
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Chen CCL; Deshmukh S; Jessa S; Hadjadj D; Lisi V; Andrade AF; Faury D; Jawhar W; Dali R; Suzuki H; Pathania M; A D; Dubois F; Woodward E; Hébert S; Coutelier M; Karamchandani J; Albrecht S; Brandner S; De Jay N; Gayden T; Bajic A; Harutyunyan AS; Marchione DM; Mikael LG; Juretic N; Zeinieh M; Russo C; Maestro N; Bassenden AV; Hauser P; Virga J; Bognar L; Klekner A; Zapotocky M; Vicha A; Krskova L; Vanova K; Zamecnik J; Sumerauer D; Ekert PG; Ziegler DS; Ellezam B; Filbin MG; Blanchette M; Hansford JR; Khuong-Quang DA; Berghuis AM; Weil AG; Garcia BA; Garzia L; Mack SC; Beroukhim R; Ligon KL; Taylor MD; Bandopadhayay P; Kramm C; Pfister SM; Korshunov A; Sturm D; Jones DTW; Salomoni P; Kleinman CL; Jabado N, 2020, 'Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis', Cell, vol. 183, pp. 1617 - 1633.e22, http://dx.doi.org/10.1016/j.cell.2020.11.012
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Leach JL; Roebker J; Schafer A; Baugh J; Chaney B; Fuller C; Fouladi M; Lane A; Doughman R; Drissi R; DeWire-Schottmiller M; Ziegler DS; Minturn JE; Hansford JR; Wang SS; Monje-Deisseroth M; Fisher PG; Gottardo NG; Dholaria H; Packer R; Warren K; Leary SES; Goldman S; Bartels U; Hawkins C; Jones BV, 2020, 'MR imaging features of diffuse intrinsic pontine glioma and relationship to overall survival: Report from the International DIPG Registry', Neuro-Oncology, vol. 22, pp. 1647 - 1657, http://dx.doi.org/10.1093/neuonc/noaa140
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Gedye C; Sachchithananthan M; Leonard R; Jeffree RL; Buckland ME; Ziegler DS; Graeber MB; Graeber MB; Day BW; McDonald KL; Lasocki A; Back M; Besser M; Boyd A; Byrne J; Cher L; Cook R; Day J; Davidson A; Devereux L; Dexter M; Donnelly R; Drummond K; Eckstein L; Gan H; Garrick T; Gottardo N; Graeber M; Harper C; Johns T; Khasraw M; Kichenadasse G; Eng-Siew K; Lipworth W; Ludlow L; Moore A; Munoz L; Nahar N; Olson S; Ormsby R; Parkinson J; Partanen A; Raymond E; Reddel R; Robbins P; Rosenthal M; Saunus J; Shivalingam B; Simes J; Stringer B; Thorne H; Vajdic C; Varikatt W; Walker D; Wheeler H; White D; Yip S; Nowak AK, 2020, 'Driving innovation through collaboration: Development of clinical annotation datasets for brain cancer biobanking', Neuro-Oncology Practice, vol. 7, pp. 31 - 37, http://dx.doi.org/10.1093/nop/npz036
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Shen H; Yu M; Tsoli M; Chang C; Joshi S; Liu J; Ryall S; Chornenkyy Y; Siddaway R; Hawkins C; Ziegler DS, 2020, 'Targeting reduced mitochondrial DNA quantity as a therapeutic approach in pediatric high-grade gliomas', Neuro-Oncology, vol. 22, pp. 139 - 151, http://dx.doi.org/10.1093/neuonc/noz140
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Khuong-Quang DA; Brown LM; Wong M; Mayoh C; Sexton-Oates A; Kumar A; Pinese M; Nagabushan S; Lau L; Ludlow LE; Gifford AJ; Rodriguez M; Desai J; Fox SB; Haber M; Ziegler DS; Hansford JR; Marshall GM; Cowley MJ; Ekert PG, 2020, 'Recurrent SPECC1L–NTRK fusions in pediatric sarcoma and brain tumors', Cold Spring Harbor Molecular Case Studies, vol. 6, http://dx.doi.org/10.1101/MCS.A005710
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Terry RL; Meyran D; Ziegler DS; Haber M; Ekert PG; Trapani JA; Neeson PJ, 2020, 'Immune profiling of pediatric solid tumors', Journal of Clinical Investigation, vol. 130, pp. 3391 - 3402, http://dx.doi.org/10.1172/JCI137181
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Vetsch J; Hetherington K; Wakefield C; Ziegler D, 2020, 'Families’ experiences of a precision medicine trial for childhood cancer', Oncology Central
    Journal articles | 2020
    Associate Professor David Simon Ziegler
    Hanson D; Hoffman LM; Nagabushan S; Goumnerova LC; Rathmann A; Vogel T; Ziegler DS; Chi S, 2020, 'A modified IRS-III chemotherapy regimen leads to prolonged survival in children with embryonal tumor with multilayer rosettes.', Neurooncol Adv, vol. 2, pp. vdaa120, http://dx.doi.org/10.1093/noajnl/vdaa120
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    Burke MJ; Ziegler DS; Bautista Sirvent FJ; Attarbaschi A; Gore L; Locatelli F; O'Brien MM; Pauly M; Obreja M; Morris CL; Baruchel A, 2019, 'Phase 1b Study of Carfilzomib in Combination with Induction Chemotherapy in Children with Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL)', Blood, vol. 134, pp. 3873 - 3873, http://dx.doi.org/10.1182/blood-2019-127350
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    Doz F; Geoerger B; DuBois SG; Grilley-Olson JE; van Tilburg CM; Italiano A; Lissat A; Jin Kang H; Tahara M; Boni V; Perreault S; Capra M; Nanda S; Brega N; Holynskyj A; Ziegler DS; Hong DS; Hyman DM; Drilon A, 2019, 'RARE-45. ACTIVITY OF LAROTRECTINIB IN TRK FUSION CANCER PATIENTS WITH PRIMARY CENTRAL NERVOUS SYSTEM TUMORS', Neuro-Oncology, vol. 21, pp. vi231 - vi231, http://dx.doi.org/10.1093/neuonc/noz175.968
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    Ziegler DS; Doz F; Geoerger B; Dubois S; Grilley-Olson JE; van Tilburg C; Italiano A; Lissat A; Kang J-H; Tahara M; Boni V; Perreault S; Capra M; Nanda S; Brega N; Holynskyj A; Hong DS; Hyman D; Drilon A, 2019, 'Activity of larotrectinib in TRK fusion cancer patients with primary central nervous system tumours', Annals of Oncology, vol. 30, pp. ix124 - ix124, http://dx.doi.org/10.1093/annonc/mdz431.003
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    Drilon AE; DuBois SG; Farago AF; Geoerger B; Grilley-Olson JE; Hong DS; Sohal D; van Tilburg CM; Ziegler DS; Ku N; Cox MC; Nanda S; Childs BH; Doz FP, 2019, 'Activity of larotrectinib in TRK fusion cancer patients with brain metastases or primary central nervous system tumors.', Journal of Clinical Oncology, vol. 37, pp. 2006 - 2006, http://dx.doi.org/10.1200/jco.2019.37.15_suppl.2006
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    DuBois SG; Albert CM; Mascarenhas L; Laetsch TW; van Tilburg CM; Potter SL; Turpin B; Glade Bender JL; Spunt SL; Hladun R; Casanova M; Ziegler DS; Morgenstern DA; Eary T; Ibabekci S; Qamoos H; Rothenberg SM; Cox MC; Balis FM; Pappo AS, 2019, 'A phase I study of LOXO-292, a highly selective RET inhibitor, in pediatric patients with RET-altered cancers.', Journal of Clinical Oncology, vol. 37, pp. TPS10066 - TPS10066, http://dx.doi.org/10.1200/jco.2019.37.15_suppl.tps10066
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    Li B; Vasiljevic A; Dufour C; Ho B; Hwang E; Gururangan S; Hansford J; Laquerriere A; Delisle M-B; Fangusaro J; Forest F; Sumihito N; Toledano H; Birks D; Fan X; Fouladi M; Gajjar A; Gauchotte G; Hoffman L; Jones C; Loussouarn D; Mokhtari K; Pomeroy S; Rousseau A; Somers G; Taylor M; Ziegler DS; Lu M; Hawkins C; Grundy R; Jouvet A; Bouffet E; Ashley Hill D; Huang A, 2019, 'PDTM-24. PINEOBLASTOMA SEGREGATES INTO MOLECULAR SUBTYPES WITH DISTINCT CLINICOPATHOLOGIC FEATURES: REPORT FROM THE RARE BRAIN TUMOUR CONSORTIUM', Neuro-Oncology, vol. 21, pp. vi192 - vi192, http://dx.doi.org/10.1093/neuonc/noz175.800
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    Vetsch J; Wakefield CE; Duve E; McGill BC; Warby M; Tucker KM; Malkin D; Lau L; Ziegler DS, 2019, 'Parents', health care professionals', and scientists' experiences of a precision medicine pilot trial for patients with high-risk childhood cancer: A qualitative study', JCO Precision Oncology, vol. 3, http://dx.doi.org/10.1200/PO.19.00235
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    Robertson EG; Wakefield CE; Cohn RJ; Battisti RA; Donoghoe MW; Ziegler DS; Fardell JE; Mitchell R; O'Brien TA, 2019, 'Piloting a parent and patient decision aid to support clinical trial decision making in childhood cancer', Psycho-Oncology, vol. 28, pp. 1520 - 1529, http://dx.doi.org/10.1002/pon.5109
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    Vetsch J; Wakefield CE; Techakesari P; Warby M; Ziegler DS; O'Brien TA; Drinkwater C; Neeman N; Tucker K, 2019, 'Healthcare professionals’ attitudes toward cancer precision medicine: A systematic review', Seminars in Oncology, vol. 46, pp. 291 - 303, http://dx.doi.org/10.1053/j.seminoncol.2019.05.001
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    Tsoli M; Shen H; Mayoh C; Franshaw L; Ehteda A; Upton D; Carvalho D; Vinci M; Meel MH; van Vuurden D; Plessier A; Castel D; Drissi R; Farrell M; Cryan J; Crimmins D; Caird J; Pears J; Francis S; Ludlow LEA; Carai A; Mastronuzzi A; Liu B; Hansford J; Gottardo N; Hassall T; Kirby M; Fouladi M; Hawkins C; Monje M; Grill J; Jones C; Hulleman E; Ziegler DS, 2019, 'International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma', Journal of Neuro-Oncology, vol. 141, pp. 253 - 263, http://dx.doi.org/10.1007/s11060-018-03038-2
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    Gamble LD; Purgato S; Murray J; Xiao L; Yu DMT; Hanssen KM; Giorgi FM; Carter DR; Gifford AJ; Valli E; Milazzo G; Kamili A; Mayoh C; Liu B; Eden G; Sarraf S; Allan S; Giacomo SD; Flemming CL; Russell AJ; Cheung BB; Oberthuer A; London WB; Fischer M; Trahair TN; Fletcher JI; Marshall GM; Ziegler DS; Hogarty MD; Burns MR; Perini G; Norris MD; Haber M, 2019, 'Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma', Science Translational Medicine, vol. 11, http://dx.doi.org/10.1126/scitranslmed.aau1099
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    Fultang L; Gamble LD; Gneo L; Berry AM; Egan SA; De Bie F; Yogev O; Eden GL; Booth S; Brownhill S; Vardon A; McConville CM; Cheng PN; Norris MD; Etchevers HC; Murray J; Ziegler DS; Chesler L; Schmidt R; Burchill SA; Haber M; De Santo C; Mussai F, 2019, 'Macrophage-derived IL1B and TNFa regulate arginine metabolism in neuroblastoma', Cancer Research, vol. 79, pp. 611 - 624, http://dx.doi.org/10.1158/0008-5472.CAN-18-2139
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    Franshaw L; Tsoli M; Lau LMS; Ziegler DS, 2019, 'Translating palbociclib to the clinic for DIPG - What is truly achievable?', EBioMedicine, vol. 45, pp. 22, http://dx.doi.org/10.1016/j.ebiom.2019.06.024
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    Rampersaud E; Ziegler DS; Iacobucci I; Payne-Turner D; Churchman ML; Schrader KA; Joseph V; Offit K; Tucker K; Sutton R; Warby M; Chenevix-Trench G; Huntsman DG; Tsoli M; Scott Mead R; Qu C; Leventaki V; Wu G; Mullighan CG, 2019, 'Germline deletion of ETV6 in familial acute lymphoblastic leukemia', Blood Advances, vol. 3, pp. 1039 - 1046, http://dx.doi.org/10.1182/bloodadvances.2018030635
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    Tsoli M; Shen H; Mayoh C; Franshaw L; Ehteda A; Upton D; Carvalho D; Vinci M; Meel MH; van Vuurden D; Plessier A; Castel D; Drissi R; Farrell M; Cryan J; Crimmins D; Caird J; Pears J; Francis S; Ludlow LEA; Carai A; Mastronuzzi A; Liu B; Hansford J; Gottardo NG; Hassall T; Kirby M; Fouladi M; Hawkins C; Monje M; Grill J; Jones C; Hulleman E; Ziegler DS, 2019, 'Correction to: International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma (Journal of Neuro-Oncology, (2019), 141, 2, (253-263), 10.1007/s11060-018-03038-2)', Journal of Neuro-Oncology, vol. 141, pp. 265, http://dx.doi.org/10.1007/s11060-018-03060-4
    Journal articles | 2019
    Associate Professor David Simon Ziegler
    Franshaw L; Tsoli M; Byrne J; Mayoh C; Sivarajasingam S; Norris M; Marshall GM; Ziegler DS, 2019, 'Predictors of Success of Phase II Pediatric Oncology Clinical Trials', Oncologist, vol. 24, pp. e765 - e774, http://dx.doi.org/10.1634/theoncologist.2017-0666
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Michaiel G; Strother D; Gottardo N; Bartels U; Coltin H; Eisenstat DD; Hukin J; Johnston DL; Wilson B; Zelcer S; Hansford JR; Wells O; AbdelBaki MS; Abu-Arja MH; Cole KA; Dhall G; Fisher PG; Hoffman L; Leary SES; Pickle EEO; Smiley NP; Smith A; Vinitsky A; Vitanza NA; Wright A; Yeo KK; Chow LML; Kirby M; Valvi S; Vanan MI; Wong G; Ziegler D; Bouffet E; Lafay-Cousin L, 2018, 'GERM-23. INTRACRANIAL GROWING TERATOMA SYNDROME (IGTS): AN INTERNATIONAL RETROSPECTIVE STUDY', Neuro-Oncology, vol. 20, pp. i88 - i88, http://dx.doi.org/10.1093/neuonc/noy059.270
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Dodgshun A; Fukuoka K; Campbell B; Edwards M; Sexton-Oates A; Larouche V; Magimairajan V; Lindhorst S; Oren M; Mason G; Crooks B; Constantini S; Massimino M; Chiaravalli S; Ramdas J; Mason W; Shamvil A; Farah R; van Damme A; Opocher E; Hamid SA; Ziegler D; Samuel D; Cole KA; Tomboc P; Stearns D; Thomas G; Lossos A; Saffery R; Sullivan M; Hansford JR; Jones D; Tabori U, 2018, 'HGG-20. DNA METHYLATION ANALYSIS OF HIGH-GRADE GLIOMA IN PATIENTS WITH MISMATCH REPAIR DEFICIENCIES', Neuro-Oncology, vol. 20, pp. i92 - i93, http://dx.doi.org/10.1093/neuonc/noy059.292
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Erker C; Lane A; Chaney B; Escorza NY; Fuller C; Saab R; Kieran M; Packer R; Nazarian J; Minturn J; Dodgshun A; Parkin S; Foreman N; Broxson E; Lombardi MG; Goldman S; Sandler E; Warren K; Greiner R; Gottardo N; Dholaria H; Shih C-S; Hassall T; Hansford JR; Wang SS; Samson Y; Leary S; Ma J; Bartels U; Broniscer A; Monje M; Fisher P; Ziegler D; Wagner L; Koschmann C; Doughman R; Drissi R; Jones B; Leach J; White P; Dexheimer P; Hendershot J; Hawkins C; Bandopadhayay P; Fouladi M, 2018, 'DIPG-69. CHARACTERISTICS OF PATIENTS ≥ 10 YEARS OF AGE WITH DIFFUSE INTRINSIC PONTINE GLIOMA: A REPORT FROM THE INTERNATIONAL DIPG REGISTRY', Neuro-Oncology, vol. 20, pp. i63 - i63, http://dx.doi.org/10.1093/neuonc/noy059.162
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Bartlett A; Cochrane A; Lane A; Yanez-Escorza N; Chaney B; Doughman R; DeWire-Schottmiller M; Goldman S; Warren K; Bandopadhayay P; Foreman N; Shih C-S; Minturn J; Bartels U; Packer R; Nazarian J; Hassall T; Samson Y; Monje-Deisseroth M; Fisher P; Wagner L; Koschmann C; Ziegler D; Kieran M; Hawkins C; White P; Dexheimer P; Hendershot J; Drissi R; Fuller C; Leach J; Jones B; Fouladi M, 2018, 'DIPG-70. CLINICAL, RADIOLOGICAL, PATHOLOGICAL AND MOLECULAR CHARACTERISTICS OF CHILDREN <3 YEARS WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): A REPORT FROM THE INTERNATIONAL DIPG REGISTRY', Neuro-Oncology, vol. 20, pp. i63 - i63, http://dx.doi.org/10.1093/neuonc/noy059.163
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Li BK; Vasiljevic A; Ho B; Jouvet A; Hwang EI; Hansford JR; Laquerriere A; Delisle M-B; Gururangan S; Fangusaro JR; Forest F; Sumihito N; Toledano H; Fouladi M; Gauchotte G; Ziegler DS; Bouffet E; Grundy RG; Dufour C; Huang AA, 2018, 'Genomic landscape of pineoblastoma.', Journal of Clinical Oncology, vol. 36, pp. 2028 - 2028, http://dx.doi.org/10.1200/jco.2018.36.15_suppl.2028
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Sagnella SM; Trieu J; Brahmbhatt H; MacDiarmid JA; MacMillan A; Whan RM; Fife CM; McCarroll JA; Gifford AJ; Ziegler DS; Kavallaris M, 2018, 'Targeted doxorubicin-loaded bacterially derived nano-cells for the treatment of neuroblastoma', Molecular Cancer Therapeutics, vol. 17, pp. 1012 - 1023, http://dx.doi.org/10.1158/1535-7163.MCT-17-0738
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Marachelian A; Hogarty MD; Flynn A; Liu K; Gerner EW; Bruckheimer E; Shamirian A; Hasenauer C; Norris M; Haber M; Groshen SG; Ziegler DS; Matthay KK, 2018, 'NANT 2012-01: Phase 1 study of DFMO and celecoxib with cyclophosphamide and topotecan for relapsed or refractory high-risk neuroblastoma.', Journal of Clinical Oncology, vol. 36, pp. 10558 - 10558, http://dx.doi.org/10.1200/jco.2018.36.15_suppl.10558
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Robertson EG; Wakefield CE; Cohn RJ; O'Brien T; Ziegler DS; Fardell JE, 2018, 'The development of delta: Using agile to develop a decision aid for pediatric oncology clinical trial enrollment', JMIR Research Protocols, vol. 7, http://dx.doi.org/10.2196/resprot.9258
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Ziegler DS; Wong M; Mayoh C; Kumar A; Tsoli M; Mould E; Tyrrell V; Khuong-Quang DA; Pinese M; Gayevskiy V; Cohn RJ; Lau LMS; Reynolds M; Cox MC; Gifford A; Rodriguez M; Cowley MJ; Ekert PG; Marshall GM; Haber M, 2018, 'Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma', British Journal of Cancer, vol. 119, pp. 693 - 696, http://dx.doi.org/10.1038/s41416-018-0251-2
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Hoffman LM; Van Zanten SEMV; Colditz N; Baugh J; Chaney B; Hoffmann M; Lane A; Fuller C; Miles L; Hawkins C; Bartels U; Bouffet E; Goldman S; Leary S; Foreman NK; Packer R; Warren KE; Broniscer A; Kieran MW; Minturn J; Comito M; Broxson E; Shih CS; Khatua S; Chintagumpala M; Carret AS; Escorza NY; Hassall T; Ziegler DS; Gottardo N; Dholaria H; Doughman R; Benesch M; Drissi R; Nazarian J; Jabado N; Boddaert N; Varlet P; Giraud G; Castel D; Puget S; Jones C; Hulleman E; Modena P; Giagnacovo M; Antonelli M; Pietsch T; Gielen GH; Jones DTW; Sturm D; Pfister SM; Gerber NU; Grotzer MA; Pfaff E; Von Bueren AO; Hargrave D; Solanki GA; Cvrlje FJ; Kaspers GJL; Vandertop WP; Grill J; Bailey S; Biassoni V; Massimino M; Calmon R; Sanchez E; Bison B; Warmuth-Metz M; Leach J; Jones B; Van Vuurden DG; Kramm CM; Fouladi M, 2018, 'Clinical, radiologic, pathologic, and molecular characteristics of long-term survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A collaborative report from the International and European Society for Pediatric Oncology DIPG registries', Journal of Clinical Oncology, vol. 36, pp. 1963 - 1972, http://dx.doi.org/10.1200/JCO.2017.75.9308
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Sun W; Malvar J; Sposto R; Verma A; Wilkes JJ; Dennis R; Heym K; Laetsch TW; Widener M; Rheingold SR; Oesterheld J; Hijiya N; Sulis ML; Huynh V; Place AE; Bittencourt H; Hutchinson R; Messinger Y; Chang B; Matloub Y; Ziegler DS; Gardner R; Cooper T; Ceppi F; Hermiston M; Dalla-Pozza L; Schultz KR; Gaynon P; Wayne AS; Whitlock JA, 2018, 'Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study', Leukemia, vol. 32, pp. 2316 - 2325, http://dx.doi.org/10.1038/s41375-018-0094-0
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Fletcher JI; Ziegler DS; Trahair TN; Marshall GM; Haber M; Norris MD, 2018, 'Too many targets, not enough patients: Rethinking neuroblastoma clinical trials', Nature Reviews Cancer, vol. 18, pp. 389 - 400, http://dx.doi.org/10.1038/s41568-018-0003-x
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Tsoli M; Wadham C; Pinese M; Failes T; Joshi S; Mould E; Yin JX; Gayevskiy V; Kumar A; Kaplan W; Ekert PG; Saletta F; Franshaw L; Liu J; Gifford A; Weber MA; Rodriguez M; Cohn RJ; Arndt G; Tyrrell V; Haber M; Trahair T; Marshall GM; McDonald K; Cowley MJ; Ziegler DS, 2018, 'Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer', Cancer Biology and Therapy, vol. 19, pp. 1078 - 1087, http://dx.doi.org/10.1080/15384047.2018.1491498
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Allanson BM; Weber MA; Jackett LA; Chan C; Lau L; Ziegler DS; Warby M; Mayoh C; Cowley MJ; Tucker KM; Long GV; Maher A; Anazodo A; Scolyer RA, 2018, 'Oral malignant gastrointestinal neuroectodermal tumour with junctional component mimicking mucosal melanoma', Pathology, vol. 50, pp. 648 - 653, http://dx.doi.org/10.1016/j.pathol.2018.07.002
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Tsoli M; Liu J; Franshaw L; Shen H; Cheng C; Jung MS; Joshi S; Ehteda A; Khan A; Montero-Carcabosso A; Dilda PJ; Hogg P; Ziegler DS, 2018, 'Dual targeting of mitochondrial function and mTOR pathway as a therapeutic strategy for diffuse intrinsic pontine glioma', Oncotarget, vol. 9, pp. 7541 - 7556, http://dx.doi.org/10.18632/oncotarget.24045
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Dixon F; Ziegler DS; Bajuk B; Wright I; Hilder L; Abdel Latif ME; Somanathan A; Oei JL, 2018, 'Treatment with nitric oxide in the neonatal intensive care unit is associated with increased risk of childhood cancer', Acta Paediatrica, International Journal of Paediatrics, vol. 107, pp. 2092 - 2098, http://dx.doi.org/10.1111/apa.14436
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Allanson BM; Weber MA; Jackett LA; Chan C; Lau L; Ziegler D; Warby M; Mayoh C; Cowley MJ; Tucker KM; Long GV; Maher A; Anazodo A; Scolyer RA, 2018, 'Oral malignant gastrointestinal neuroectodermal tumour with junctional component mimicking mucosal melanoma.', Pathology, vol. 50, pp. 648 - 653, http://dx.doi.org/10.1016/j.pathol.2018.07.002
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Kabalan P; Gifford AJ; Ziegler DS, 2018, 'Unresectable VIP-secreting neuroblastoma: Efficacy of debulking and steroids for symptom control', Pediatric Blood and Cancer, vol. 65, http://dx.doi.org/10.1002/pbc.27358
    Journal articles | 2018
    Associate Professor David Simon Ziegler
    Vedi A; Mitchell R; Shanmuganathan S; Oswald C; Marshall GM; Trahair T; Sivarajasingam S; Ziegler DS, 2018, 'Increased Survival for Children with Acute Myeloid Leukemia Results from Improved Postrelapse Treatment', Journal of Pediatric Hematology/Oncology, vol. 40, pp. 541 - 547, http://dx.doi.org/10.1097/MPH.0000000000001215
    Journal articles | 2017
    Associate Professor David Simon Ziegler
    Durno CA; Aronson M; Edwards M; Ling S; Larouche V; Bronsema A; Osborn M; Stearns D; Cole K; Oren M; Opocher E; Mason GE; Thomas G; Sabel M; George B; Ziegler D; Lindhorst S; Magimairajan V; Laperriere N; Samuel D; Bouffet E; Tabori U, 2017, 'Immune Check Point Inhibitor Treatment for Young Patients with Hypermutant Cancers', Gastroenterology, vol. 152, pp. S141 - S141, http://dx.doi.org/10.1016/s0016-5085(17)30801-6
    Journal articles | 2017
    Associate Professor David Simon Ziegler
    Campbell BB; Angelini P; Fabrizio D; Elvin J; Light N; Bouffet E; Larouche V; Samuel D; Stearns D; Cole K; Opocher E; Thomas G; Sabel M; George B; Ziegler D; Lapierre N; Mason G; Magimajrajan V; Shlien A; Tabori U, 2017, 'IMMU-13. LARGE SCALE TUMOR MUTATIONAL BURDEN ANALYSIS OF PEDIATRIC TUMORS PROVIDES A DIAGNOSTIC TOOL FOR GERMLINE PREDISPOSITION AND REVEALS NOVEL CANDIDATES FOR IMMUNE CHECKPOINT INHIBITION', Neuro-Oncology, vol. 19, pp. iv30 - iv30, http://dx.doi.org/10.1093/neuonc/nox083.123
    Journal articles | 2017
    Associate Professor David Simon Ziegler
    Campbell BB; Angelini P; Light N; Bouffet E; Larouche V; Samuel D; Stearns D; Cole KA; Opocher E; Sabel M; George B; Ziegler D; Laperriere N; Meyn S; Malkin D; Shlien A; Tabori U, 2017, 'PDTM-21. LARGE SCALE TUMOR MUTATIONAL BURDEN ANALYSIS OF PEDIATRIC TUMORS PROVIDES A DIAGNOSTIC TOOL FOR GERMLINE PREDISPOSITION AND REVEALS NOVEL CANDIDATES FOR IMMUNE CHECKPOINT INHIBITION', Neuro-Oncology, vol. 19, pp. vi194 - vi194, http://dx.doi.org/10.1093/neuonc/nox168.785
    Journal articles | 2017
    Associate Professor David Simon Ziegler
    Sadras T; Heatley SL; Kok CH; McClure BJ; Yeung D; Hughes TP; Sutton R; Ziegler DS; White DL, 2017, 'A novel somatic JAK2 kinase-domain mutation in pediatric acute lymphoblastic leukemia with rapid on-treatment development of LOH', Cancer Genetics, vol. 216-217, pp. 86 - 90, http://dx.doi.org/10.1016/j.cancergen.2017.07.008
    Journal articles | 2017
    Associate Professor David Simon Ziegler
    Campbell BB; Light N; Fabrizio D; Zatzman M; Fuligni F; de Borja R; Davidson S; Edwards M; Elvin JA; Hodel KP; Zahurancik WJ; Suo Z; Lipman T; Wimmer K; Kratz CP; Bowers DC; Laetsch TW; Dunn GP; Johanns TM; Grimmer MR; Smirnov IV; Larouche V; Samuel D; Bronsema A; Osborn M; Stearns D; Raman P; Cole KA; Storm PB; Yalon M; Opocher E; Mason G; Thomas GA; Sabel M; George B; Ziegler DS; Lindhorst S; Issai VM; Constantini S; Toledano H; Elhasid R; Farah R; Dvir R; Dirks P; Huang A; Galati MA; Chung J; Ramaswamy V; Irwin MS; Aronson M; Durno C; Taylor MD; Rechavi G; Maris JM; Bouffet E; Hawkins C; Costello JF; Meyn MS; Pursell ZF; Malkin D; Tabori U; Shlien A, 2017, 'Comprehensive Analysis of Hypermutation in Human Cancer', Cell, vol. 171, pp. 1042 - 1056.e10, http://dx.doi.org/10.1016/j.cell.2017.09.048
    Journal articles | 2017
    Associate Professor David Simon Ziegler
    Lapin DH; Tsoli M; Ziegler DS, 2017, 'Genomic insights into diffuse intrinsic pontine glioma', Frontiers in Oncology, vol. 7, http://dx.doi.org/10.3389/fonc.2017.00057
    Journal articles | 2017
    Associate Professor David Simon Ziegler
    Baugh J; Bartels U; Leach J; Jones B; Chaney B; Warren KE; Kirkendall J; Doughman R; Hawkins C; Miles L; Fuller C; Hassall T; Bouffet E; Lane A; Hargrave D; Grill J; Hoffman LM; Jones C; Towbin A; Savage SA; Monje M; Li XN; Ziegler DS; Veldhuijzen van Zanten S; Kramm CM; van Vuurden DG; Fouladi M, 2017, 'The international diffuse intrinsic pontine glioma registry: an infrastructure to accelerate collaborative research for an orphan disease', Journal of Neuro-Oncology, vol. 132, pp. 323 - 331, http://dx.doi.org/10.1007/s11060-017-2372-5
    Journal articles | 2017
    Associate Professor David Simon Ziegler
    Hennika T; Hu G; Olaciregui NG; Barton KL; Ehteda A; Chitranjan A; Chang C; Gifford AJ; Tsoli M; Ziegler DS; Carcaboso AM; Becher OJ, 2017, 'Pre-clinical study of panobinostat in xenograft and genetically engineered murine diffuse intrinsic pontine glioma models', PLoS ONE, vol. 12, http://dx.doi.org/10.1371/journal.pone.0169485
    Journal articles | 2017
    Associate Professor David Simon Ziegler
    Bhojwani D; Burke MJ; Horton T; Ziegler DS; Sulis ML; Schultz KR; Wayne A; Izraeli S; Chang BH, 2017, 'Investigating the biology of relapsed acute leukemia: Proceedings of the Therapeutic Advances for Childhood Leukemia & Lymphoma (TACL) Consortium Biology Working Group', Pediatric Hematology and Oncology, vol. 34, pp. 355 - 364, http://dx.doi.org/10.1080/08880018.2017.1395937
    Journal articles | 2017
    Associate Professor David Simon Ziegler
    Valvi S; Ziegler DS, 2017, 'Ganglioglioma arising from desmoplastic medulloblastoma: A case report and review of literature', Pediatrics, vol. 139, http://dx.doi.org/10.1542/peds.2016-1403
    Journal articles | 2016
    Associate Professor David Simon Ziegler
    Franshaw L; Sivarajasingam S; Byrne J; Dalla-Pozza L; Marshall G; Norris M; Ziegler DS, 2016, 'Predictors of success of phase 2 paediatric oncology clinical trials', European Journal of Cancer, vol. 69, pp. S63 - S64, http://dx.doi.org/10.1016/s0959-8049(16)32778-2
    Journal articles | 2016
    Associate Professor David Simon Ziegler
    Liu PY; Sokolowski N; Guo ST; Siddiqi F; Atmadibrata B; Telfer TJ; Sun Y; Zhang L; Yu D; Mccarroll J; Liu B; Yang RH; Guo XY; Tee AE; Itoh K; Wang J; Kavallaris M; Haber M; Norris MD; Cheung BB; Byrne JA; Ziegler DS; Marshall GM; Dinger ME; Codd R; Zhang XD; Liu T, 2016, 'The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs', Oncotarget, vol. 7, pp. 79217 - 79232, http://dx.doi.org/10.18632/oncotarget.12640
    Journal articles | 2016
    Associate Professor David Simon Ziegler
    Barbaro PM; Ziegler DS; Reddel RR, 2016, 'The wide-ranging clinical implications of the short telomere syndromes', Internal Medicine Journal, vol. 46, pp. 393 - 403, http://dx.doi.org/10.1111/imj.12868
    Journal articles | 2016
    Associate Professor David Simon Ziegler
    Davis T; Doyle H; Tobias V; Ellison DW; Ziegler DS, 2016, 'Case report of spontaneous resolution of a congenital glioblastoma', Pediatrics, vol. 137, http://dx.doi.org/10.1542/peds.2015-1241
    Journal articles | 2016
    Associate Professor David Simon Ziegler
    Evageliou NF; Haber M; Vu A; Laetsch TW; Murray J; Gamble LD; Cheng NC; Liu K; Reese M; Corrigan KA; Ziegler DS; Webber H; Hayes CS; Pawel B; Marshall GM; Zhao H; Gilmour SK; Norris MD; Hogarty MD, 2016, 'Polyamine antagonist therapies inhibit neuroblastoma initiation and progression', Clinical Cancer Research, vol. 22, pp. 4391 - 4404, http://dx.doi.org/10.1158/1078-0432.CCR-15-2539
    Journal articles | 2015
    Associate Professor David Simon Ziegler
    Carter DR; Murray J; Cheung BB; Gamble L; Koach J; Tsang J; Sutton S; Kalla H; Syed S; Gifford AJ; Issaeva N; Biktasova A; Atmadibrata B; Sun Y; Sokolowski N; Ling D; Kim PY; Webber H; Clark A; Ruhle M; Liu B; Oberthuer A; Fischer M; Byrne J; Saletta F; Thwe LM; Purmal A; Haderski G; Burkhart C; Speleman F; De Preter K; Beckers A; Ziegler DS; Liu T; Gurova KV; Gudkov AV; Norris MD; Haber M; Marshall GM, 2015, 'Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma', Science Translational Medicine, vol. 7, http://dx.doi.org/10.1126/scitranslmed.aab1803
    Journal articles | 2015
    Associate Professor David Simon Ziegler
    Ziegler DS, 2015, 'Never say never', Journal of Clinical Oncology, vol. 33, pp. 518 - 520, http://dx.doi.org/10.1200/JCO.2014.58.7717
    Journal articles | 2014
    Associate Professor David Simon Ziegler
    Whitlock J; dalla Pozza L; Goldberg JM; Silverman LB; Ziegler DS; Attarbaschi A; Brown P; Gardner RA; Gaynon PS; Hutchinson RJ; Marcus LJ; Messinger YH; Schultz KR; Vandergiessen J; Eckroth E; Locatelli F; Zwaan CM; Wood BL; Sposto R; Gore L, 2014, 'Nelarabine in Combination with Etoposide and Cyclophosphamide Is Active in First Relapse of Childhood T-Acute Lymphocytic Leukemia (T-ALL) and T-Lymphoblastic Lymphoma (T-LL)', Blood, vol. 124, pp. 795 - 795, http://dx.doi.org/10.1182/blood.v124.21.795.795
    Journal articles | 2014
    Associate Professor David Simon Ziegler
    Saletta F; Wadham C; Byrne J; Ziegler D; McCowage G; Haber M; Marshall G; Norris M, 2014, '421 Molecular profiling for factors predicting sensitivity or resistance to therapy in relapsed child cancer', European Journal of Cancer, vol. 50, pp. 135 - 135, http://dx.doi.org/10.1016/s0959-8049(14)70547-7
    Journal articles | 2014
    Associate Professor David Simon Ziegler
    Williams P; Wegner E; Ziegler DS, 2014, 'Outcomes in multifocal neuroblastoma as part of the neurocristopathy syndrome', Pediatrics, vol. 134, http://dx.doi.org/10.1542/peds.2013-3340
    Journal articles | 2014
    Associate Professor David Simon Ziegler
    Saletta F; Wadham C; Ziegler DS; Marshall GM; Haber M; McCowage G; Norris MD; Byrne JA, 2014, 'Molecular profiling of childhood cancer: Biomarkers and novel therapies', BBA Clinical, vol. 1, pp. 59 - 77, http://dx.doi.org/10.1016/j.bbacli.2014.06.003
    Journal articles | 2014
    Associate Professor David Simon Ziegler
    Vedi A; ziegler D, 2014, 'Antibody therapy for pediatric leukemia', Frontiers in Oncology, vol. 4, pp. 1 - 10, http://dx.doi.org/10.3389/fonc.2014.00082
    Journal articles | 2013
    Associate Professor David Simon Ziegler
    Mateos MK; O'Brien TA; Oswald C; Ziegler DS; Cohn RJ; Russell SJ; Barbaric D; Marshall GM; Trahair TN; Gabriel M, 2013, 'Transplant-related mortality following allogeneic hematopoeitic stem cell transplantation for pediatric acute lymphoblastic leukemia: 25-year retrospective review', Pediatric Blood and Cancer, vol. 60, pp. 1520 - 1527, http://dx.doi.org/10.1002/pbc.24559
    Journal articles | 2013
    Associate Professor David Simon Ziegler
    Shah S; Schrader KA; Vijai J; Miething C; Hayes J; Klein RJ; Gao X; Kitzing T; Lowe SW; Offit K; Littman J; Offit L; Rau-Murthy R; Fleischut MH; Corines M; Manschreck C; Waanders E; Wei L; Ma J; Chen S-C; Song G; Cheng J; Raimondi SC; Roberts KG; Downing JR; Mullighan CG; Kuiper RP; Simons A; Timms AE; Wechsler J; Horwitz MS; Yang J; Zhang J; Wu G; Rusch M; Nagahawatte P; Meyers P; Bhojwani D; Sandlund JT; Jhanwar S; Murali R; Maslak P; Fleisher M; Murty VV; Schiffman JD; Onel K; Plon SE; Wheeler DA; Ritter D; Ziegler DS; Sutton R; Tucker K; Chenevix-Trench G; Li J; Huntsman DG; Hansford S; Senz J; Walsh T; Lee M; King M-C; Hahn CN; Scott HS; Lo SM; Levine RL; Viale A; Socci ND; Nathanson KL; Daly M; Lipkin SM; Altshuler D, 2013, 'A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia', Nature Genetics, vol. 45, pp. 1226 - 1231, http://dx.doi.org/10.1038/ng.2754
    Journal articles | 2012
    Associate Professor David Simon Ziegler
    Ziegler D, 2012, 'Erratum: Treatment of diabetic neuropathy and neuropathic pain: How far have we come? (Diabetes Care (2008) 31 Suppl. 2, (S255-S261) DOI: 10.2337/dc08-s263)', Diabetes Care, vol. 35, pp. 456, http://dx.doi.org/10.2337/dc12-rt02
    Journal articles | 2012
    Associate Professor David Simon Ziegler
    Gamble LD; Hogarty MD; Liu X; Ziegler DS; Marshall GM; Norris MD; Haber M, 2012, 'Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma', Frontiers in Oncology, vol. 2, pp. 1 - 10, http://dx.doi.org/10.3389/fonc.2012.00162
    Journal articles | 2012
    Associate Professor David Simon Ziegler
    Bock V; Ziegler DS; Wargon O; Gray PEA, 2012, 'Neonatal Sweet Syndrome: A potential marker of serious systemic illness', Pediatrics, vol. 129, pp. e1353 - e1359, http://dx.doi.org/10.1542/peds.2011-1854
    Journal articles | 2012
    Associate Professor David Simon Ziegler
    Keating J; Tsoli M; Hallahan AR; Ingram WJ; Haber M; Ziegler DS, 2012, 'Targeting the inhibitor of apoptosis proteins as a novel therapeutic strategy in medulloblastoma', Molecular Cancer Therapeutics, vol. 11, pp. 2654 - 2663, http://dx.doi.org/10.1158/1535-7163.MCT-12-0352
    Journal articles | 2012
    Associate Professor David Simon Ziegler
    Argent E; Emder PJ; Monagle P; Mowat DR; Petterson T; Russell SJ; Sachdev RR; Stone C; Ziegler DS, 2012, 'Australian paediatric surveillance unit study of haemoglobinopathies in australian children', Journal of Paediatrics and Child Health, vol. 48, pp. 356 - 360, http://dx.doi.org/10.1111/j.1440-1754.2011.02236.x
    Journal articles | 2011
    Associate Professor David Simon Ziegler
    Barbaro PM; Johnston K; Dalla-Pozza L; Cohn RJ; Wang YA; Marshall GM; Ziegler DS, 2011, 'Reduced incidence of second solid tumors in survivors of childhood Hodgkin's lymphoma treated without radiation therapy', Annals of Oncology, vol. 22, pp. 2569 - 2574, http://dx.doi.org/10.1093/annonc/mdr013
    Journal articles | 2011
    Associate Professor David Simon Ziegler
    McCowage G; Mrongovius R; Alvaro F; Cohn RJ; Ziegler DS; Oswald CM; White L, 2011, 'Treatment of children with poor risk solid tumors by further escalation of the VETOPEC regimen including very high-dose cyclophosphamide and peripheral stem cell support: An Australian and New Zealand children's hematology and oncology group study', Pediatric Blood and Cancer, vol. 57, pp. 958 - 964, http://dx.doi.org/10.1002/pbc.23042
    Journal articles | 2011
    Associate Professor David Simon Ziegler
    Ziegler D; Rosentock J; Portenoy R, 2011, 'Effective management of diabetic neuropathy - Pregabalin relieves the neuropathic pain', Diabetes Aktuell, vol. 9, pp. 237, http://dx.doi.org/10.1055/s-0031-1286694
    Journal articles | 2011
    Associate Professor David Simon Ziegler
    Ziegler DS; Keating J; Kesari S; Fast EM; Zawel L; Ramakrishnan N; Barnes J; Kieran MW; Van zanten SEMV; Kung AL, 2011, 'A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo', Neuro - Oncology, vol. 13, pp. 820 - 829, http://dx.doi.org/10.1093/neuonc/nor066
    Journal articles | 2010
    Associate Professor David Simon Ziegler
    Ueberberg S; Ziegler D; Schechinger W; Dietrich JW; Akinturk S; Klein HH; Schneider S, 2010, 'In vitro phage display in a rat beta cell line: A simple approach for the generation of a single-chain antibody targeting a novel beta cell-specific epitope', Diabetologia, vol. 53, pp. 1384 - 1394, http://dx.doi.org/10.1007/s00125-010-1725-9
    Journal articles | 2009
    Associate Professor David Simon Ziegler
    Satharasinghe K; Trahair TN; Barbaric D; O'Brien TA; Russell SJ; Cohn RJ; Marshall GM; Ziegler DS, 2009, 'False-positive MIBG scans with normal computed tomography imaging in patients with high-risk neuroblastoma', Journal of Clinical Oncology, vol. 27, http://dx.doi.org/10.1200/JCO.2009.24.0036
    Journal articles | 2008
    Associate Professor David Simon Ziegler
    Ziegler DS; Kung A; Kieran M, 2008, 'Anti-apoptosis mechanisms in malignant gliomas', Journal of Clinical Oncology, vol. 26, pp. 493 - 500, http://dx.doi.org/10.1200/JCO.2007.13.9717
    Journal articles | 2008
    Associate Professor David Simon Ziegler
    Ziegler DS; Wright RD; Kesari S; Lemieux ME; Tran MA; Jain M; Zawel L; Kung AL, 2008, 'Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins', Journal of Clinical Investigation, vol. 118, pp. 3109 - 3122, http://dx.doi.org/10.1172/JCI34120
    Journal articles | 2008
    Associate Professor David Simon Ziegler
    Ziegler DS; Klung A, 2008, 'Therapeutic targeting of apoptosis pathways in cancer', Current Opinion Oncology, vol. 20, pp. 97 - 103, http://dx.doi.org/10.1097/CCO.0b013e3282f310f6
    Journal articles | 2008
    Associate Professor David Simon Ziegler
    Ziegler DS; Wright R; Kesari S; Lemieux M; Tran M; Jain M; Zawei L; Kung A, 2008, 'Resistance of human glioblastoma multiformed cells to growth factor inhibitor of apoptosis proteins', The Journal of Clinical Investigation, vol. 2118, pp. 3109 - 3122
    Journal articles | 2006
    Associate Professor David Simon Ziegler
    Ziegler DS; McCowage G; Cohn RJ; White L, 2006, 'Long-term survival following a phase I/II trial with VETOPEC for solid tumors in childhood', Journal of Pediatric Hematology and Oncology, vol. 28, pp. 40 - 42
    Journal articles | 2006
    Associate Professor David Simon Ziegler
    Ziegler DS; Cohn RJ; McCowage G; Alvaro F; Oswald CM; Mrongovius R; White L, 2006, 'Efficacy of vincristine and etoposide with escalating cyclophosphamide in poor-prognosis pediatric brain tumors', Neuro - Oncology, vol. 8, pp. 53 - 59, http://dx.doi.org/10.1215/S1522851705000463
    Journal articles | 2005
    Associate Professor David Simon Ziegler
    Ziegler DS; Pozza LD; Waters KD; Marshall GM, 2005, 'Advances in childhood leukaemia', Medical Journal of Australia, vol. 182, pp. 364 - 365, http://dx.doi.org/10.5694/j.1326-5377.2005.tb06740.x
    Journal articles | 2005
    Associate Professor David Simon Ziegler
    Hocking B; Ziegler DS; Dalla Pozza L; Waters KD; Marshall GM, 2005, 'Advances in childhood leukaemia (multiple letters) [2]', Medical Journal of Australia, vol. 182, pp. 364 - 365, http://dx.doi.org/10.5694/j.1326-5377.2005.tb06739.x
    Journal articles | 2005
    Associate Professor David Simon Ziegler
    Ziegler DS; Dalla Pozza L; Waters K; Marshall GM, 2005, 'Advances in childhood leukaemia: successful clinical-trials research leads to individualised therapy', Medical Journal of Australia, vol. 182, pp. 78 - 81
    Journal articles | 2005
    Associate Professor David Simon Ziegler
    Ziegler DS; Sammut JF; Piper AC, 2005, 'Assessment and follow up of suspected child abuse in preschool children with fractures seen in a general hospital emergency department.', Journal of Paediatrics and Child Health (Vol. 48, Suppl. 2, 2012, 1–13), vol. 41, pp. 251 - 255, http://dx.doi.org/10.1111/j.1440-1754.2005.00605.x
    Journal articles | 2005
    Associate Professor David Simon Ziegler
    Ziegler DS; Cohn RJ; Duffy B; Sutton R; Norris MD, 2005, 'PCR for monoclonal gene rearrangements can differentiate infantile acute lymphoblastic leukemia from cytomegalovirus infection', Leukemia Research, vol. 29, pp. 111 - 112, http://dx.doi.org/10.1016/j.leukres.2004.03.023
    Journal articles | 2005
    Associate Professor David Simon Ziegler
    Ziegler DS; Russell SJ; Rozenberg G; James CA; Trahair TN; O'Brien TA, 2005, 'Goats' milk quackery', Journal of Paediatrics and Child Health, vol. 41, pp. 569 - 571, http://dx.doi.org/10.1111/j.1440-1754.2005.00723.x
    Journal articles | 2005
    Associate Professor David Simon Ziegler
    Haysom L; Ziegler DS; Cohn RJ; Rosenberg A; Carroll SL; Kainer G, 2005, 'Retinoic acid may increase the risk of bone marrow transplant nephrology', Pediatric Nephrology, vol. 20, pp. 534 - 538, http://dx.doi.org/10.1007/s00467-004-1775-7
    Journal articles | 2005
    Associate Professor David Simon Ziegler
    Ziegler DS; Piper AC; Sammut J, 2005, 'Physical injury in young children: The differential diagnosis must include child abuse (vol 41, pg 251, 2005)', JOURNAL OF PAEDIATRICS AND CHILD HEALTH, vol. 41, pp. 474 - 474, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000231566400004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2005
    Associate Professor David Simon Ziegler
    Ziegler DS; Pozza LD; Waters KD; Marshall GM, 2005, 'Advances in childhood leukaemia - Reply', MEDICAL JOURNAL OF AUSTRALIA, vol. 182, pp. 365 - 365, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000229273600017&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2003
    Associate Professor David Simon Ziegler
    Scanlon DM; Ziegler DS; Mantzouranis EC; Boicos SA; Bagourakis GS, 2003, 'Throat clearing in asthma [5] (multiple letters)', New England Journal of Medicine, vol. 349, pp. 194 - 195, http://dx.doi.org/10.1056/NEJM200307103490220
    Journal articles | 2001
    Associate Professor David Simon Ziegler
    Ziegler D; Bent G, 2001, 'Caustic-induced upper airway obstruction responsive to nebulized adrenaline [5]', Pediatrics, vol. 107, pp. 807 - 808, http://dx.doi.org/10.1542/peds.107.4.807
    Journal articles | 2001
    Associate Professor David Simon Ziegler
    Ziegler DS; Bent GP, 2001, 'Upper airway obstruction induced by a caustic substance found responsive to nebulised adrenaline [3]', Journal of Paediatrics and Child Health, vol. 37, pp. 524 - 525, http://dx.doi.org/10.1046/j.1440-1754.2001.0742c.x
  • Conference Abstracts | 2020
    Associate Professor David Simon Ziegler
    Barahona P; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Haber M; Lock RB; Marshall GM; Mayoh C; Mould E; Nagabushan S; Norris M; O’Brien T; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Ziegler DS; Tyrrell VJ; Ekert P; Cowley MJ; Lau L; Quang D-AK, 2020, 'Abstract A52: Zero Childhood Cancer (ZERO): A comprehensive precision medicine platform for children with high-risk cancer', in Poster Presentations - Proffered Abstracts, American Association for Cancer Research, presented at Abstracts: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada, http://dx.doi.org/10.1158/1538-7445.pedca19-a52
    Conference Abstracts | 2020
    Associate Professor David Simon Ziegler
    Khan A; Gamble L; Pandher R; Burns MR; Mussai F; Norris M; Haber M; Tsoli M; Ziegler DS, 2020, 'DIPG-16. COMBINATION OF ARGININE DEPLETION AND POLYAMINE INHIBITION AS AN ANTICANCER STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii290 - iii290, http://dx.doi.org/10.1093/neuonc/noaa222.066
    Conference Abstracts | 2020
    Associate Professor David Simon Ziegler
    Upton D; Valvi S; Liu J; Yeung N; George S; Ung C; Khan A; Franshaw L; Ehteda A; Shen H; Orienti I; Farruggia G; Nath C; Reynolds P; Tsoli M; Ziegler D, 2020, 'DIPG-07. HIGH THROUGHPUT DRUG SCREENING IDENTIFIES POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGs)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii288 - iii288, http://dx.doi.org/10.1093/neuonc/noaa222.058
    Conference Abstracts | 2020
    Associate Professor David Simon Ziegler
    Ehteda A; Franshaw L; Liu J; Joshi S; Simon S; Pang CNI; Giorgi F; Pandher R; Ung C; Tolhurst O; Mayoh C; Khan A; Hayden E; Gopalakrishnan A; Trebilcock P; Upton D; Lehmann R; George S; Vittorio O; Tsoli M; Gurova K; Gudkov AG; Norris MD; Haber M; Ziegler DS, 2020, 'DIPG-27. TARGETING FACILITATES CHROMATIN TRANSCRIPTION (FACT) AS A NOVEL STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) THAT ENHANCES RESPONSE TO HISTONE DEACETYLASE (HDAC) INHIBITION', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii292 - iii292, http://dx.doi.org/10.1093/neuonc/noaa222.076
    Conference Abstracts | 2020
    Associate Professor David Simon Ziegler
    Khan A; Gamble L; Upton D; Yu D; Ehteda A; Pandher R; Mayoh C; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2020, 'DIPG-15. POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii289 - iii290, http://dx.doi.org/10.1093/neuonc/noaa222.065
    Conference Abstracts | 2020
    Associate Professor David Simon Ziegler
    Duchatel RJ; Mannan A; Jackson ER; Staudt D; Skerrett-Byrne DA; Jamaluddin MFB; Woldu AS; Douglas A; Hulleman E; Carcaboso AM; Monje M; Alvaro F; Tsoli M; Ziegler DS; Dun MD, 2020, 'DIPG-29. PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE (PI3K) INHIBITION DRIVES PROTEIN KINASE C ACTIVATION (PKC) IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii292 - iii293, http://dx.doi.org/10.1093/neuonc/noaa222.078
    Conference Abstracts | 2020
    Associate Professor David Simon Ziegler
    Franshaw L; Hayden E; Joshi S; Liu J; Ehteda A; Pang CNI; Tsoli M; Ziegler DS, 2020, 'DIPG-14. TARGETING POLO-LIKE KINASE 1 IN COMBINATION WITH KEY ONCOGENIC DRIVERS IN DIPG: FROM SINGLE AGENT TO COMBINATION STRATEGIES', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii289 - iii289, http://dx.doi.org/10.1093/neuonc/noaa222.064
    Conference Abstracts | 2020
    Associate Professor David Simon Ziegler
    Ung C; Tsoli M; Liu J; Cassano D; Upton D; Ehteda A; Mansfield F; Failes T; Kavallaris M; Arndt G; Vittorio O; Voliani V; Cirilo G; Ziegler DS, 2020, 'DDEL-12. NANOPARTICLE DELIVERY OF DOXORUBICIN FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii286 - iii286, http://dx.doi.org/10.1093/neuonc/noaa222.047
    Conference Abstracts | 2020
    Associate Professor David Simon Ziegler
    Haber M; Cowley MJ; Ekert P; Lau L; Mould E; Gifford A; Lock RB; Marshall GM; Norris MD; O'Brien T; Dong AKQ; Thomas D; Trahair T; Tucker K; Ziegler DS; Tyrrell V, 2020, 'Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer in Australia', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, Vol. 80, presented at AACR Annual Meeting, ELECTR NETWORK, 22 June 2020 - 24 June 2020, http://dx.doi.org/10.1158/1538-7445.AM2020-SY09-02
    Conference Papers | 2020
    Associate Professor David Simon Ziegler
    Mondal S; Wong M; Tee A; Ho N; Ziegler DS; Marshall GM; Liu PY; Dinger M; Liu T, 2020, 'The super-enhancer driven long noncoding RNA lncNB promotes neuroblastoma tumorigenesis', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, presented at AACR Annual Meeting, ELECTR NETWORK, 22 June 2020 - 24 June 2020, http://dx.doi.org/10.1158/1538-7445.AM2020-5721
    Conference Papers | 2020
    Associate Professor David Simon Ziegler
    Barahona P; Sherstyuk A; Cowley M; Ekert P; Kirk J; Khuong-Quang D-A; Kumar A; Lau L; Mayoh C; Marshall G; Moud E; O’Brien T; Pinese M; Thomas D; Tyrell V; Ziegler D; Haber M; Tucker K; Fuentes-Bolanos NA; Warby M, 2020, 'Abstract A03: Prevalence and spectrum of germline mutations in children with high-risk cancer', in Poster Presentations - Proffered Abstracts, American Association for Cancer Research, presented at Abstracts: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada, http://dx.doi.org/10.1158/1538-7445.pedca19-a03
    Conference Papers | 2020
    Associate Professor David Simon Ziegler
    Ung C; Tsoli M; Liu J; Cassano D; Upton D; Ehteda A; Mansfield F; Failes T; Kavallaris M; Arndt G; Vittorio O; Voliani V; Cirilo G; Ziegler DS, 2020, 'NANOPARTICLE DELIVERY OF DOXORUBICIN FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 286 - 286, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100048&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Associate Professor David Simon Ziegler
    Duchatel R; Jackson E; Patabendige A; Cain J; Tsoli M; Monje M; Alvaro F; Ziegler D; Dun M, 2019, 'DIPG-03. TARGETING PI3K USING THE BLOOD BRAIN BARRIER PENETRABLE INHIBITOR, GDC-0084, FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 21, pp. ii68 - ii68, http://dx.doi.org/10.1093/neuonc/noz036.024
    Conference Abstracts | 2019
    Associate Professor David Simon Ziegler
    Haber M; Gamble L; Xiao L; Pandher R; Somers K; Murray J; Khan A; Yu D; Franshaw L; Burns MR; Tsoli M; Ehteda A; Cesare A; O'Connor A; Mussai F; de Santo C; Cheng P; Korotchkina L; Gurova K; Tyrrell V; Mould E; Lau L; Dong AKQ; Mayoh C; Arndt G; Barahona P; Failes T; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Gifford A; Grebert-Wade D; Kamili A; Kumar A; Nagabushan S; O'Brien T; Strong P; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Xie J; Evans K; Lock R; Chernova OB; Henderson M; Gudkov AV; Ekert P; Cowley MJ; Marshall GM; Ziegler DS; Norris MD, 2019, 'Molecular targeted therapies and precision medicine for children with neuroblastoma and other refractory malignancies', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Montreal, CANADA, Vol. 80, pp. 23 - 24, presented at AACR Special Conference on the Advances in Pediatric Cancer Research, Montreal, CANADA, 17 September 2019 - 20 September 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000551367400013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Associate Professor David Simon Ziegler
    Tsoli M; Lau L; Barahona P; Mayoh C; Failes T; Wong M; Sherstyuk A; Gifford AJ; Kumar A; Mould E; Ung C; Tolhurst O; Gopalakrishnan A; Grebert-Wade D; Strong P; Trebilcock P; Lock R; Tyrrell V; Trahair T; Tucker K; Warby M; Arndt G; Norris M; Haber M; Marshall G; O’Brien T; Quang DAK; Cowley M; Ekert P; Ziegler DS, 2019, 'THER-23. RESULTS OF THE ZERO CHILDHOOD CANCER INTEGRATED PRECISION MEDICINE PLATFORM FOR PAEDIATRIC HIGH-RISK BRAIN TUMOURS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 21, pp. ii118 - ii118, http://dx.doi.org/10.1093/neuonc/noz036.228
    Conference Abstracts | 2018
    Associate Professor David Simon Ziegler
    Mokgwathi OL; Ziegler DS; Currie B; Tucker K; Gifford AJ, 2018, 'Pleuropulmonary blastoma – Case report of a rare tumour harbouring a DICER1 mutation', in Pathology, Elsevier BV, Vol. 50, pp. S144 - S144, http://dx.doi.org/10.1016/j.pathol.2017.11.062
    Conference Abstracts | 2018
    Associate Professor David Simon Ziegler
    Johnson A; Bye A; Ziegler D; Gifford A; Jacobsen E; Cohn R, 2018, 'CRAN-27. PAEDIATRIC EXTRAVENTRICULAR NEUROCYTOMA: A SERIES AND A RARE COMPLICATION', in Neuro-Oncology, Oxford University Press (OUP), Vol. 20, pp. i42 - i42, http://dx.doi.org/10.1093/neuonc/noy059.063
    Conference Abstracts | 2018
    Associate Professor David Simon Ziegler
    Robertson EG; Mitchell R; Wakefield CE; Lewis P; Cousens N; Marshall GM; Russell SJ; Ziegler DS; Anazodo A; Trahair TN; Barbaric D; Cohn RJ; Alvaro F; O'Brien TA, 2018, 'Enrolment in early phase paediatric oncology clinical trials: the healthcare professionals’ perspective.', in PSYCHO-ONCOLOGY, WILEY, Hong Kong, Vol. 27, pp. 56 - 57, presented at International Psycho-Oncology Society, Hong Kong, 31 October 2018 - 02 November 2018, http://dx.doi.org/10.1111/jpc.14248
    Conference Abstracts | 2018
    Associate Professor David Simon Ziegler
    Khan A; Gamble L; Yu D; Joshi S; Franshaw L; Burns M; Norris M; Haber M; Tsoli M; Ziegler D, 2018, 'DIPG-01. TARGETING THE POLYAMINE PATHWAY AS A NOVEL THERAPEUTIC TREATMENT AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 20, pp. i49 - i49, http://dx.doi.org/10.1093/neuonc/noy059.095
    Conference Abstracts | 2018
    Associate Professor David Simon Ziegler
    Ziegler D; Tsoli M; Tyrell V; Cohn R; Lau L; Cox M; Cowley M; Ekert P; Marshall G; Haber M, 2018, 'EAPH-09. POTENT CLINICAL AND RADIOLOGICAL RESPONSE TO LAROTRECTINIB IN FIRST CASE OF TRK FUSION HIGH GRADE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 20, pp. i67 - i67, http://dx.doi.org/10.1093/neuonc/noy059.178
    Conference Abstracts | 2018
    Associate Professor David Simon Ziegler
    Khan A; Tsoli M; Yu D; Joshi S; Gamble L; Franshaw L; Haber M; Ziegler DS, 2018, 'Abstract 4800: Targeting the polyamine pathway as a novel therapeutic treatment against diffuse intrinsic pontine glioma', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL, http://dx.doi.org/10.1158/1538-7445.am2018-4800
    Conference Papers | 2018
    Associate Professor David Simon Ziegler
    Robertson EG; Mitchell R; Wakefield CE; Lewis P; Cousens N; Marshall GM; Russell SJ; Ziegler DS; Anazodo AC; Trahair TN; Barbaric D; Cohn RJ; Alvaro F; O'Brien T, 2018, 'Enrolment in early phase paediatric oncology clinical trials: the healthcare professionals’ perspective (poster)', in Enrolment in early phase paediatric oncology clinical trials: the healthcare professionals’ perspective (poster), Australian and New Zealand Children’s Haematology and Oncology Group (ANZCHOG), Sydney, presented at Australian and New Zealand Children’s Haematology and Oncology Group (ANZCHOG), Sydney, 14 June 2018 - 16 June 2018
    Conference Presentations | 2018
    Associate Professor David Simon Ziegler
    Anazodo A; Hau P; Hovey E; Nowak A; Pfister S; Hesketh E; Bhadri V; Koh E; Ziegler D, 2018, 'Personalised targeted therapy for adolescent and young adult medulloblastoma patients.', presented at 3rd Global Adolescent and Young Adult Cancer Congress Program, Sheraton Grand Sydney, 04 December 2018 - 06 December 2018, https://www.eiseverywhere.com/ehome/312967
    Conference Papers | 2017
    Associate Professor David Simon Ziegler
    Burns MR; Fosnaugh K; Palfreyman MG; Gamble L; Murray J; Allan S; Eden G; Sarraf S; Norris M; Ziegler D; Haber M, 2017, 'Abstract 2006: AMX-513 polyamine depletion therapy inhibits tumor growth and reverses immunosuppression in cancers including MYC-driven neuroblastoma and pancreatic cancer', in Tumor Biology, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC, http://dx.doi.org/10.1158/1538-7445.am2017-2006
    Conference Abstracts | 2017
    Associate Professor David Simon Ziegler
    Lau L; Byrne J; Ekert PG; Failes T; Fellowes A; Fletcher J; Gifford A; Haber M; Kumar A; Lock R; Marshall G; McCowage GB; Mould E; Norris M; Trahair T; Tsoli M; Tyrrell V; Wadham C; Xie J; Ziegler DS, 2017, 'Pilot study of a comprehensive precision medicine platform for children with high-risk cancer.', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, Chicago, IL, Vol. 35, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL, 02 June 2017 - 06 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.15_suppl.10539
    Conference Abstracts | 2017
    Associate Professor David Simon Ziegler
    Ehteda A; Kankean A; Chitranjan A; Tsoli M; Liu J; Shen H; Franshaw L; Joshi S; Chang C; Ager E; Ziegler DS, 2017, 'DIPG-09. TRX-E-009-1 IS A NOVEL AND A POTENT THERAPEUTIC AGENT FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv6 - iv6, http://dx.doi.org/10.1093/neuonc/nox083.024
    Conference Abstracts | 2017
    Associate Professor David Simon Ziegler
    Franshaw L; Tsoli M; Byrne J; Sivarajasingam S; Norris M; Marshall G; Ziegler D, 2017, 'TRTH-05. PREDICTORS OF SUCCESS OF PHASE 2 PAEDIATRIC ONCOLOGY CLINICAL TRIALS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv52 - iv52, http://dx.doi.org/10.1093/neuonc/nox083.217
    Conference Abstracts | 2017
    Associate Professor David Simon Ziegler
    Shen H; Chang C; Joshi S; Liu J; Tsoli M; Hau E; Ziegler D, 2017, 'DIPG-02. RADIOSENSITIVITY OF DIPG CELLS IS ENHANCED BY TARGETING GLUCOSE METABOLISM IN VITRO AND IN VIVO', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv5 - iv5, http://dx.doi.org/10.1093/neuonc/nox083.017
    Conference Abstracts | 2017
    Associate Professor David Simon Ziegler
    Tsoli M; Lapin D; Franshaw L; Shen H; Liu J; Ziegler D, 2017, 'DIPG-04. COMBINED TARGETING OF CALCIUM SIGNALLING AND RTK/PI3K PATHWAY IS A NOVEL THERAPEUTIC APPROACH AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv5 - iv5, http://dx.doi.org/10.1093/neuonc/nox083.019
    Conference Abstracts | 2017
    Associate Professor David Simon Ziegler
    Tsoli M; Yeung N; Valvi S; Joshi S; Franshaw L; Shen H; Liu J; Ziegler D, 2017, 'DIPG-05. COMBINATION OF SYNTHETIC RETINOID FENRETINIDE WITH RECEPTOR TYROSINE KINASE INHIBITOR PONATINIB AS A POTENTIAL NEW APPROACH AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv5 - iv6, http://dx.doi.org/10.1093/neuonc/nox083.020
    Conference Abstracts | 2017
    Associate Professor David Simon Ziegler
    Franshaw L; Chang C; Joshi S; Ehteda A; Tsoli M; Ziegler D, 2017, 'DIPG-07. INDUCING DNA LETHALITY THROUGH POLO-LIKE KINASE 1 INHIBITION: A NOVEL THERAPEUTIC APPROACH IN DIPG', in Neuro-Oncology, Oxford University Press (OUP), Vol. 19, pp. iv6 - iv6, http://dx.doi.org/10.1093/neuonc/nox083.022
    Conference Papers | 2016
    Associate Professor David Simon Ziegler
    Wadham C; Saletta F; Byrne JA; Trahair T; Ziegler DS; McCowage G; Marshall G; Haber M; Norris M, 2016, 'Abstract 51: Molecular profiling of relapsed childhood cancer', in Other Topics, American Association for Cancer Research, presented at Abstracts: AACR Precision Medicine Series: Integrating Clinical Genomics and Cancer Therapy; June 13-16, 2015; Salt Lake City, UT, http://dx.doi.org/10.1158/1557-3265.pmsclingen15-51
    Conference Abstracts | 2016
    Associate Professor David Simon Ziegler
    Shen H; Tsoli M; Chang C; Chitranjan A; Liu J; Hau E; Kankean A; Ehteda A; Franshaw L; Valvi S; Ziegler D, 2016, 'HG-04DICHLOROACETATE AND METFORMIN COMBINE TO MODULATE GLUCOSE METABOLISM AND POTENTLY SENSITISE DIPG CELLS TO RADIATION THERAPY', in Neuro-Oncology, Oxford University Press (OUP), Vol. 18, pp. iii48.3 - iii48, http://dx.doi.org/10.1093/neuonc/now073.03
    Conference Abstracts | 2016
    Associate Professor David Simon Ziegler
    Valvi S; Tsoli M; Chitranjan A; Shen H; Chang C; Kankean A; Ehteda A; Franshaw L; Liu J; Ziegler D, 2016, 'HG-25FENRETINIDE TARGETS THE RTK-PI3K PATHWAY IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in Neuro-Oncology, Oxford University Press (OUP), Vol. 18, pp. iii52.5 - iii53, http://dx.doi.org/10.1093/neuonc/now073.22
    Conference Abstracts | 2016
    Associate Professor David Simon Ziegler
    Tsoli M; Chang C; Shen H; Liu J; Chintranjan A; Franshaw L; Dilda P; Carcaboso AM; Hogg P; Ziegler D, 2016, 'HG-19COMBINED TARGETING OF MITOCHONDRIAL FUNCTION AND mTOR IS A POTENT NOVEL THERAPEUTIC APPROACH FOR DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 18, pp. iii51.3 - iii51, http://dx.doi.org/10.1093/neuonc/now073.16
    Conference Abstracts | 2016
    Associate Professor David Simon Ziegler
    Ehteda A; Tsoli M; Chitranjan A; Chang C; Simon S; Kankean A; Shen H; Liu J; Haber M; Gudkov A; Ziegler D, 2016, 'HG-20COMBINATION OF EPIGENETIC MODIFIERS CBL0137 AND PANOBINOSTAT IS HIGHLY POTENT IN VITRO AND IN VIVO FOR DIFFUSE INTRINSIC PONTINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 18, pp. iii51.4 - iii51, http://dx.doi.org/10.1093/neuonc/now073.17
    Conference Abstracts | 2015
    Associate Professor David Simon Ziegler
    Kankean A; Tsoli M; Tsang J; Chitranjan A; Maleki S; McDonald K; Ziegler D, 2015, 'HG-16 * THE ANTI-APOPTOTIC PROTEIN ARC IS OVER-EXPRESSED IN MALIGNANT GLIOMA AND CORRELATES WITH PATIENT OUTCOME', in Neuro-Oncology, Oxford University Press (OUP), Vol. 17, pp. iii14 - iii14, http://dx.doi.org/10.1093/neuonc/nov061.53
    Conference Abstracts | 2015
    Associate Professor David Simon Ziegler
    Kankean A; Ehteda A; Chitranjan A; Tsoli M; Ager E; Ziegler D, 2015, 'BT-09 * TRILEXIUM INHIBITS THE EXPRESSION OF t-NOX AND IS A NOVEL, POTENTIALLY POTENT THERAPY FOR DIFFUSE INTRINSIC PONTINE GLIOMAS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 17, pp. iii5 - iii5, http://dx.doi.org/10.1093/neuonc/nov061.19
    Conference Papers | 2015
    Associate Professor David Simon Ziegler
    Vedi A; Mitchell R; Oswald C; Marshall GM; Trahair T; Ziegler DS, 2015, 'Increased Use of Allogeneic Transplant in CR2 Improves the Outcome for Children with Acute Myeloid Leukaemia', in BLOOD, AMER SOC HEMATOLOGY, Orlando, FL, presented at 57th Annual Meeting of the American-Society-of-Hematology, Orlando, FL, 05 December 2015 - 08 December 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000368020102033&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Associate Professor David Simon Ziegler
    Haber M; Murray J; Gamble L; Carnegie-Clark A; Webber H; Ruhle M; Henderson MJ; Middlemass S; Carter D; Tsoli M; Ehteda A; Simon S; Oberthuer A; Fischer M; Gurova K; Burkhart C; Purmal A; Lock RB; Ziegler D; Marshall GM; Gudkov AV; Norris MD, 2015, 'The FACT histone chaperone complex is highly expressed in aggressive drug refractory childhood cancers and the anti-FACT compound CBL0137 represents a highly promising therapeutic approach in this setting', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Philadelphia, PA, Vol. 75, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia, PA, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-1611
    Conference Papers | 2014
    Associate Professor David Simon Ziegler
    Haber M; Murray J; Gamble L; Carnegie-Clark A; Webber H; Ruhle M; Carter D; Oberthur A; Fischer M; Ziegler D; Marshall GM; Gurova K; Burkhart C; Purmal A; Gudkov AV; Norris MD, 2014, 'CBL0137, a novel NFkB suppressor and p53 activator, is highly effective in pre-clinical models of neuroblastoma', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, European Org Res & Treatment Canc, Barcelona, SPAIN, pp. 135 - 135, presented at 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, European Org Res & Treatment Canc, Barcelona, SPAIN, 18 November 2014 - 21 November 2014, http://dx.doi.org/10.1016/S0959-8049(14)70548-9
    Conference Abstracts | 2013
    Associate Professor David Simon Ziegler
    Mitic G; Tsoli M; Ziegler DS; Kavallaris M, 2013, 'beta III-tubulin in glioblastoma: An emerging multifactorial survival factor role in chemotherapy response and tumor formation.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, Vol. 73, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-3431
    Conference Papers | 2013
    Associate Professor David Simon Ziegler
    Norris MD; Gamble LD; Murray J; Purqato S; Miiazzo G; Ashton LJ; Oberthuer A; London WB; Hogarty MD; Fischer M; Ziegler D; Marshall GM; Perini G; Haber M, 2013, 'MYCN coordinately regulates the entire polyamine gene pathway to drive polyamine biosynthesis in neuroblastoma, with expression of every synthetic and catabolic polyamine pathway gene being highly prognostic of clinical outcome', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-3808
    Conference Abstracts | 2012
    Associate Professor David Simon Ziegler
    Mitic G; Tsoli M; Ziegler DS; Kavallaris M, 2012, 'beta III-TUBULIN AND GLIOBLASTOMA: ROLE IN DRUG RESISTANCE AND TUMOURIGENESIS', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, Vol. 8, pp. 303 - 304, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310544400264&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2004
    Associate Professor David Simon Ziegler
    Ziegler DS; Cohn RJ; McCowage G; Alvaro F; Oswald C; Mrongovius R; White F, 2004, 'Efficacy of high-dose cyclophosphamide with etoposide and vinchistine ("VETOPEC") in very high-risk paediatric brain tumours', in NEURO-ONCOLOGY, DUKE UNIV PRESS, Boston, MA, pp. 469 - 469, presented at 11th International Symposium on Pediatric Neuro-Oncology, Boston, MA, 13 June 2004 - 16 June 2004, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000224332400610&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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