Dr Denovan Begg

Dr Denovan Begg

Senior Lecturer
Science
School of Psychology

ABOUT ME

 

Biography

My research is primarily focused on the field of behavioural neuroscience. I examine the central nervous systems regulation of food, fluid and nutrient intake. I also examine the effects of macro and micro nutrients on the brain and behaviour.

Education

    • PhD, Nutritional Neuroscience, Deakin University, 2011
    • MBSc, Behavioural Neuroscience, La Trobe University, 2008
    • BBSc (Hons), Behavioural Science, La Trobe University, 2003

 

RESEARCH

 

Research Goals

      • The homeostatic regulation of ingestive behaviour and body weight regulation
      • The transport of adiposity signals across the blood brain barrier
      • The cardiovascular effects of dietary fatty acids and their metabolites
      • The role of eicosanoids in the stress response

Research in Detail

The primary goals of my lab are (1) to examine the mechanisms underlying obesity and (2) to examine how dietary changes alter behaviour. The lab uses both in vivo and in vitro models to examine transport of adiposity signals across the blood brain barrier. Techniques utilized by the lab include a range of genetic models, behavioural tests, small animal surgery and molecular approaches.

Research Grants

      • CJ Martin fellowship, 2011-2015, The renin-angiotensin system and obesity

Current Student Projects (PhD and Honours)

The cyclooxygenase-eicosanoid pathway and stress-induced spatial learning deficits.

Supervision Opportunities/Areas

Physiological factors altering transport of the adiposity signal insulin into the central nervous system.

The effect of dietary fatty acids and eicosanoid inhibition on the stress response.

What are the causal links between angiotensin, obesity and inflammation?

Advice for prospective students

If you are interested in potential honours of higher degree projects, or if you would like to gain some experience in a neuroscience lab, email me to discuss the options available to you.

 

TEACHING & OUTREACH

 

Courses I teach

PSYC1011 - Psychology 1B

Professional affiliations and service positions

Society for the Study of Ingestive Behavior.

International Society for the Study of Fatty Acids and Lipids.

The Endocrine Society.

American Heart Association.

Neuroendocrinology Australasia.

 

AWARDS & ACHIEVEMENTS

 

2009 - Society for the Study of Ingestive Behavior, New Investigator Travel Award.

2012 - International Society for the Study of Fatty Acids and Lipids (ISSFAL), New Investigator Award.

Phone
0293852441
Location
Matthews Building, Room 708
  • Book Chapters | 2016
    Mathai ML; Weisinger RS; Weisinger HS; Begg DP, 2016, 'Salt appetite', in The Curated Reference Collection in Neuroscience and Biobehavioral Psychology, pp. 445 - 452, http://dx.doi.org/10.1016/B978-0-12-809324-5.02765-6
    Book Chapters | 2014
    Begg D; Woods SC, 2014, 'Hunger and Satiety Signaling', in Ardies CM (ed.), Diet, Exercise, and Chronic Disease, CRC Press, pp. 391 - 404, http://dx.doi.org/10.1201/b16783
    Book Chapters | 2014
    2014, 'Atherosclerosis', in Diet, Exercise, and Chronic Disease, CRC Press, pp. 147 - 224, http://dx.doi.org/10.1201/b16783-9
    Book Chapters | 2009
    Weisinger RS; Begg DP; Mathai ML; Weisinger HS, 2009, 'Salt Appetite', in Encyclopedia of Neuroscience, Elsevier, pp. 445 - 452, http://dx.doi.org/10.1016/b978-008045046-9.00470-8
    Book Chapters | 2007
    Weisinger RS; Begg DP; Stahl L; Weisinger HS; Sinclair AJ; Jois M, 2007, 'The role of omega-3 polyunsaturated fatty acids in food intake and energy homeostasis', in Fatty Acids in Foods and their Health Implications, Third Edition, pp. 837 - 854
  • Journal articles | 2024
    Rafiei N; Mitchell CS; Tedesco CR; Chen J; Choi EA; Roughley S; Jean-Richard-dit-Bressel P; Kumar NN; McNally GP; Herzog H; Begg DP, 2024, 'Chemogenetic activation ofarcuate nucleus NPY and NPY/AgRP neurons increases feeding behaviour in mice', Neuropeptides, 107, http://dx.doi.org/10.1016/j.npep.2024.102454
    Journal articles | 2023
    Sah S; Keable R; Pfundstein G; Clemens KJ; Begg D; Schachner M; Leshchyns’ka I; Sytnyk V, 2023, 'Deficiency in the neural cell adhesion molecule 2 (NCAM2) reduces axonal levels of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1), affects axonal organization in the hippocampus, and leads to behavioral deficits', Cerebral Cortex, 33, pp. 10047 - 10065, http://dx.doi.org/10.1093/cercor/bhad264
    Journal articles | 2022
    Goodman EK; Mitchell CS; Teo JD; Gladding JM; Abbott KN; Rafiei N; Zhang L; Herzog H; Begg DP, 2022, 'The effect of insulin receptor deletion in neuropeptide Y neurons on hippocampal dependent cognitive function in aging mice', Journal of Integrative Neuroscience, 21, http://dx.doi.org/10.31083/j.jin2101006
    Journal articles | 2022
    Mitchell CS; Goodman EK; Tedesco CR; Nguyen K; Zhang L; Herzog H; Begg DP, 2022, 'The Effect of Dietary Fat and Sucrose on Cognitive Functioning in Mice Lacking Insulin Signaling in Neuropeptide Y Neurons', Frontiers in Physiology, 13, http://dx.doi.org/10.3389/fphys.2022.841935
    Journal articles | 2022
    SUCQUART IE; NAGARKAR R; EDWARDS MC; PARIS VRODRIGUEZ; AFLATOUNIAN A; BERTOLDO MJ; CAMPBELL RE; BEGG DP; HANDELSMAN DJ; PADMANABHAN V; ANDERSON RA; GILCHRIST RB; WALTERS KA, 2022, 'Pharmacological Antagonism of the Kisspeptin-Neurokinin System Improved Adverse Metabolic Traits in a PCOS Mouse Model', Fertility & Reproduction, 04, pp. 160 - 160, http://dx.doi.org/10.1142/s2661318222740723
    Journal articles | 2021
    Flavel M; Ellis TP; Stahl L; Begg D; Smythe J; Ilag LL; Weisinger RS; Kitchen B; Jois M, 2021, 'Polyphenol rich sugarcane extract reduces body weight in c57/bl6j mice fed a high fat, high carbohydrate diet', Applied Sciences (Switzerland), 11, http://dx.doi.org/10.3390/app11115163
    Journal articles | 2021
    Homberg JR; Adan RAH; Alenina N; Asiminas A; Bader M; Beckers T; Begg DP; Blokland A; Burger ME; van Dijk G; Eisel ULM; Elgersma Y; Englitz B; Fernandez-Ruiz A; Fitzsimons CP; van Dam AM; Gass P; Grandjean J; Havekes R; Henckens MJAG; Herden C; Hut RA; Jarrett W; Jeffrey K; Jezova D; Kalsbeek A; Kamermans M; Kas MJ; Kasri NN; Kiliaan AJ; Kolk SM; Korosi A; Korte SM; Kozicz T; Kushner SA; Leech K; Lesch KP; Lesscher H; Lucassen PJ; Luthi A; Ma L; Mallien AS; Meerlo P; Mejias JF; Meye FJ; Mitchell AS; Mul JD; Olcese U; González AO; Olivier JDA; Pasqualetti M; Pennartz CMA; Popik P; Prickaerts J; de la Prida LM; Ribeiro S; Roozendaal B; Rossato JI; Salari AA; Schoemaker RG; Smit AB; Vanderschuren LJMJ; Takeuchi T; van der Veen R; Smidt MP; Vyazovskiy VV; Wiesmann M; Wierenga CJ; Williams B; Willuhn I; Wöhr M; Wolvekamp M; van der Zee EA; Genzel L, 2021, 'The continued need for animals to advance brain research', Neuron, 109, pp. 2374 - 2379, http://dx.doi.org/10.1016/j.neuron.2021.07.015
    Journal articles | 2021
    Le JT; Watson P; Begg D; Albertella L; Le Pelley ME, 2021, 'Physiological and subjective validation of a novel stress procedure: The Simple Singing Stress Procedure', Behavior Research Methods, 53, pp. 1478 - 1487, http://dx.doi.org/10.3758/s13428-020-01505-1
    Journal articles | 2021
    Mitchell CS; Begg DP, 2021, 'The regulation of food intake by insulin in the central nervous system', Journal of Neuroendocrinology, 33, http://dx.doi.org/10.1111/jne.12952
    Journal articles | 2021
    Mitchell CS; Premaratna SD; Bennett G; Lambrou M; Stahl LA; Jois M; Barber E; Antoniadis CP; Woods SC; Cameron-Smith D; Weisinger RS; Begg DP, 2021, 'Inhibition of the Renin-Angiotensin System Reduces Gene Expression of Inflammatory Mediators in Adipose Tissue Independent of Energy Balance', Frontiers in Endocrinology, 12, pp. 682726, http://dx.doi.org/10.3389/fendo.2021.682726
    Journal articles | 2021
    Sucquart IE; Nagarkar R; Edwards MC; Rodriguez Paris V; Aflatounian A; Bertoldo MJ; Campbell RE; Gilchrist RB; Begg DP; Handelsman DJ; Padmanabhan V; Anderson RA; Walters KA, 2021, 'Neurokinin 3 Receptor Antagonism Ameliorates Key Metabolic Features in a Hyperandrogenic PCOS Mouse Model', Endocrinology (United States), 162, http://dx.doi.org/10.1210/endocr/bqab020
    Journal articles | 2020
    Begg DP; Sinclair AJ; Weisinger RS, 2020, 'Impaired Fluid Intake, but Not Sodium Appetite, in Aged Rats Is Mediated by the Cyclooxygenase-Prostaglandin E2 Pathway', Frontiers in Aging Neuroscience, 12, pp. 19, http://dx.doi.org/10.3389/fnagi.2020.00019
    Journal articles | 2019
    Begg DP, 2019, 'Insulin transport and activity in the central nervous system', Obesity Research & Clinical Practice, 13, pp. 40 - 41, http://dx.doi.org/10.1016/j.orcp.2016.10.054
    Journal articles | 2019
    Begg DP, 2019, 'Vertical sleeve gastrectomy and hypertension in diet-induced obese rodents', Obesity Research & Clinical Practice, 13, pp. 278 - 278, http://dx.doi.org/10.1016/j.orcp.2018.11.125
    Journal articles | 2019
    Goulter N; Kimonis ER; Denson TF; Begg DP, 2019, 'Female primary and secondary psychopathic variants show distinct endocrine and psychophysiological profiles', Psychoneuroendocrinology, 104, pp. 7 - 17, http://dx.doi.org/10.1016/j.psyneuen.2019.02.011
    Journal articles | 2019
    Ip CK; Zhang L; Farzi A; Qi Y; Clarke I; Reed F; Shi YC; Enriquez R; Dayas C; Graham B; Begg D; Brüning JC; Lee NJ; Hernandez-Sanchez D; Gopalasingam G; Koller J; Tasan R; Sperk G; Herzog H, 2019, 'Amygdala NPY Circuits Promote the Development of Accelerated Obesity under Chronic Stress Conditions', Cell Metabolism, 30, pp. 111 - 128.e6, http://dx.doi.org/10.1016/j.cmet.2019.04.001
    Journal articles | 2018
    Gladding JM; Abbott KN; Antoniadis CP; Stuart A; Begg DP, 2018, 'The Effect of Intrahippocampal Insulin Infusion on Spatial Cognitive Function and Markers of Neuroinflammation in Diet-induced Obesity', Frontiers in Endocrinology, 9, pp. 752, http://dx.doi.org/10.3389/fendo.2018.00752
    Journal articles | 2018
    Woods SC; May-Zhang AA; Begg DP, 2018, 'How and why do gastrointestinal peptides influence food intake?', Physiology and Behavior, 193, pp. 218 - 222, http://dx.doi.org/10.1016/j.physbeh.2018.02.048
    Journal articles | 2017
    Begg DP, 2017, 'Disturbances of thirst and fluid balance associated with aging', Physiology and Behavior, 178, pp. 28 - 34, http://dx.doi.org/10.1016/j.physbeh.2017.03.003
    Journal articles | 2017
    Loh K; Zhang L; Brandon A; Wang Q; Begg D; Qi Y; Fu M; Kulkarni R; Teo J; Baldock P; Bruning JC; Cooney G; Neely GG; Herzog H, 2017, 'Corrigendum to “Insulin controls food intake and energy balance via NPY neurons” [Mol Metabol 6 (2017) 574–584], (S2212877817301552), (10.1016/j.molmet.2017.03.013))', Molecular Metabolism, 6, pp. 1562, http://dx.doi.org/10.1016/j.molmet.2017.06.017
    Journal articles | 2017
    Loh K; Zhang L; Brandon A; Wang Q; Begg D; Qi Y; Fu M; Kulkarni R; Teo J; Baldock P; Brüning JC; Cooney G; Neely G; Herzog H, 2017, 'Insulin controls food intake and energy balance via NPY neurons', Molecular Metabolism, 6, pp. 574 - 584, http://dx.doi.org/10.1016/j.molmet.2017.03.013
    Journal articles | 2017
    Rodger P; Jois M; Weisinger R; Begg D, 2017, 'Molasses extract improves body composition and glucose metabolism of mice on a high-fat diet', Journal of Nutrition & Intermediary Metabolism, 8, pp. 82 - 82, http://dx.doi.org/10.1016/j.jnim.2017.04.080
    Journal articles | 2017
    Woods SC; May AA; Liu M; Tso P; Begg DP, 2017, 'Using the cerebrospinal fluid to understand ingestive behavior', Physiology and Behavior, 178, pp. 172 - 178, http://dx.doi.org/10.1016/j.physbeh.2016.11.037
    Journal articles | 2016
    May AA; Liu M; Woods SC; Begg DP, 2016, 'CCK increases the transport of insulin into the brain', Physiology and Behavior, 165, pp. 392 - 397, http://dx.doi.org/10.1016/j.physbeh.2016.08.025
    Journal articles | 2016
    Woods SC; Begg DP, 2016, 'Regulation of the motivation to eat', Current Topics in Behavioral Neurosciences, 27, pp. 15 - 34, http://dx.doi.org/10.1007/7854_2015_381
    Journal articles | 2015
    Begg DP; May AA; Mul JD; Liu M; D'Alessio DA; Seeley RJ; Woods SC, 2015, 'InsulinDetemir is transported fromblood to cerebrospinal fluid and has prolonged central anorectic action relative to NPH Insulin', Diabetes, 64, pp. 2457 - 2466, http://dx.doi.org/10.2337/db14-1364
    Journal articles | 2015
    Begg DP, 2015, 'Insulin Transport into the Brain and Cerebrospinal Fluid', Vitamins and Hormones, 98, pp. 229 - 248, http://dx.doi.org/10.1016/bs.vh.2014.12.007
    Journal articles | 2015
    Obici S; Magrisso IJ; Ghazarian AS; Shirazian A; Miller JR; Loyd CM; Begg DP; Krawczewski Carhuatanta KA; Haas MK; Davis JF; Woods SC; Sandoval DA; Seeley RJ; Goodyear LJ; Pothos EN; Mul JD, 2015, 'Moderate voluntary exercise attenuates the metabolic syndrome in melanocortin-4 receptor-deficient rats showing central dopaminergic dysregulation', Molecular Metabolism, 4, pp. 692 - 705, http://dx.doi.org/10.1016/j.molmet.2015.07.003
    Journal articles | 2015
    Woods SC; Begg DP, 2015, 'Food for thought: Revisiting the complexity of food intake', Cell Metabolism, 22, pp. 348 - 351, http://dx.doi.org/10.1016/j.cmet.2015.08.017
    Journal articles | 2014
    Begg DP; Steinbrecher KA; Mul JD; Chambers AP; Kohli R; Haller A; Cohen MB; Woods SC; Seeley RJ, 2014, 'Effect of guanylate cyclase-C activity on energy and glucose homeostasis', Diabetes, 63, pp. 3798 - 3804, http://dx.doi.org/10.2337/db14-0160
    Journal articles | 2014
    Chambers AP; Smith EP; Begg DP; Grayson BE; Sisley S; Greer T; Sorrell J; Lemmen L; LaSance K; Woods SC; Seeley RJ; D'Alessio DA; Sandoval DA, 2014, 'Regulation of gastric emptying rate and its role in nutrient-induced GLP-1 secretion in rats after vertical sleeve gastrectomy', American Journal of Physiology - Endocrinology and Metabolism, 306, pp. e424 - e432, http://dx.doi.org/10.1152/ajpendo.00469.2013
    Journal articles | 2014
    Cichello SA; Begg D; Jois M; Weisinger R, 2014, 'Addition of 2% crushed fenugreek seed to a high-fat diet reduces bone mineral density in C57Bl/6J mice', Nutritional Therapy and Metabolism, 32, pp. 146 - 151, http://dx.doi.org/10.5301/NTM.2014.12690
    Journal articles | 2014
    Cichello SA; Begg D; Weisinger R, 2014, 'Anxiety behaviour displayed in C57BL/6J mice consuming coffee and cocoa, but not observed in mice consuming Japanese green tea in a high fat diet induced obesity model', Current Research in Nutrition and Food Science, 2, pp. 33 - 39, http://dx.doi.org/10.12944/CRNFSJ.2.1.05
    Journal articles | 2014
    Grayson BE; Fitzgerald MF; Hakala-Finch AP; Ferris VM; Begg DP; Tong J; Woods SC; Seeley RJ; Davidson TL; Benoit SC, 2014, 'Improvements in hippocampal-dependent memory and microglial infiltration with calorie restriction and gastric bypass surgery, but not with vertical sleeve gastrectomy', International Journal of Obesity, 38, pp. 349 - 356, http://dx.doi.org/10.1038/ijo.2013.100
    Journal articles | 2014
    Hafandi A; Begg DP; Premaratna SD; Sinclair AJ; Jois M; Weisinger RS, 2014, 'Dietary repletion with ω3 fatty acid or with COX inhibition reverses cognitive effects in F3 ω3 fatty-acid-deficient mice', Comparative Medicine, 64, pp. 106 - 109
    Journal articles | 2014
    Mul JD; Begg DP; Haller AM; Pressler JW; Sorrell J; Woods SC; Farese RV; Seeley RJ; Sandoval DA, 2014, 'MGAT2 deficiency and vertical sleeve gastrectomy have independent metabolic effects in the mouse', American Journal of Physiology - Endocrinology and Metabolism, 307, pp. E1065 - E1072, http://dx.doi.org/10.1152/ajpendo.00376.2014
    Journal articles | 2014
    Ryan KK; Mul JD; Clemmensen C; Egan AE; Begg DP; Halcomb K; Seeley RJ; Herman JP; Ulrich-Lai YM, 2014, 'Loss of melanocortin-4 receptor function attenuates HPA responses to psychological stress', Psychoneuroendocrinology, 42, pp. 98 - 105, http://dx.doi.org/10.1016/j.psyneuen.2014.01.010
    Journal articles | 2013
    Begg DP; Mul JD; Liu M; Reedy BM; D'Alessio DA; Seeley RJ; Woods SC, 2013, 'Reversal of diet-induced obesity increases insulin transport into cerebrospinal fluid and restores sensitivity to the anorexic action of central insulin in male rats', Endocrinology, 154, pp. 1047 - 1054, http://dx.doi.org/10.1210/en.2012-1929
    Journal articles | 2013
    Begg DP; Woods SC, 2013, 'Hedonic and homeostatic overlap following fat ingestion', Cell Metabolism, 18, pp. 459 - 460, http://dx.doi.org/10.1016/j.cmet.2013.09.012
    Journal articles | 2013
    Begg DP; Woods SC, 2013, 'Interactions between the central nervous system and pancreatic islet secretions: A historical perspective', American Journal of Physiology - Advances in Physiology Education, 37, pp. 53 - 60, http://dx.doi.org/10.1152/advan.00167.2012
    Journal articles | 2013
    Begg DP; Woods SC, 2013, 'The endocrinology of food intake', Nature Reviews Endocrinology, 9, pp. 584 - 597, http://dx.doi.org/10.1038/nrendo.2013.136
    Journal articles | 2013
    Cichello SA; Begg DP; Jois M; Weisinger RS, 2013, 'Prevention of diet-induced obesity in C57BL/BJ mice with addition of 2 % dietary green tea but not with cocoa or coffee to a high-fat diet', Mediterranean Journal of Nutrition and Metabolism, 6, pp. 233 - 238, http://dx.doi.org/10.1007/s12349-013-0137-z
    Journal articles | 2013
    Cichello SA; Begg DP; Jois M; Weisinger RS, 2013, 'Prevention of diet-induced obesity in C57BL/BJ mice with addition of 2 % dietary green tea but not with cocoa or coffee to a high-fat diet', Mediterranean Journal of Nutrition and Metabolism, 6, pp. 233 - 238, http://dx.doi.org/10.3233/s12349-013-0137-z
    Journal articles | 2013
    Mul JD; Begg DP; Barrera JG; Li B; Matter EK; D'Alessio DA; Woods SC; Seeley RJ; Sandoval DA, 2013, 'High-fat diet changes the temporal profile of GLP-1 receptor-mediated hypophagia in rats', American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 305, http://dx.doi.org/10.1152/ajpregu.00588.2012
    Journal articles | 2013
    Mul JD; Seeley RJ; Woods SC; Begg DP, 2013, 'Angiotensin-converting enzyme inhibition reduces food intake and weight gain and improves glucose tolerance in melanocortin-4 receptor deficient female rats', Physiology and Behavior, 121, pp. 43 - 48, http://dx.doi.org/10.1016/j.physbeh.2013.01.013
    Journal articles | 2013
    Stemmer K; Bielohuby M; Grayson BE; Begg DP; Chambers AP; Neff C; Woods SC; Erben RG; Tschöp MH; Bidlingmaier M; Clemens TL; Seeley RJ, 2013, 'Roux-en-Y gastric bypass surgery but not vertical sleeve gastrectomy decreases bone mass in male rats', Endocrinology, 154, pp. 2015 - 2024, http://dx.doi.org/10.1210/en.2012-2130
    Journal articles | 2012
    Begg DP; Puskás LG; Kitajka K; Ménesi D; Allen AM; Li D; Mathai ML; Shi JR; Sinclair AJ; Weisinger RS, 2012, 'Hypothalamic gene expression in ω-3 PUFA-deficient male rats before, and following, development of hypertension', Hypertension Research, 35, pp. 381 - 387, http://dx.doi.org/10.1038/hr.2011.194
    Journal articles | 2012
    Begg DP; Sinclair AJ; Weisinger RS, 2012, 'Reductions in water and sodium intake by aged male and female rats', Nutrition Research, 32, pp. 865 - 872, http://dx.doi.org/10.1016/j.nutres.2012.09.014
    Journal articles | 2012
    Begg DP; Sinclair AJ; Weisinger RS, 2012, 'Thirst deficits in aged rats are reversed by dietary omega-3 fatty acid supplementation', Neurobiology of Aging, 33, pp. 2422 - 2430, http://dx.doi.org/10.1016/j.neurobiolaging.2011.12.001
    Journal articles | 2012
    Begg DP; Woods SC, 2012, 'The central insulin system and energy balance', Handbook of Experimental Pharmacology, 209, pp. 111 - 129, http://dx.doi.org/10.1007/978-3-642-24716-3_5
    Journal articles | 2012
    Liu M; Shen L; Begg DP; D'alessio DA; Woods SC, 2012, 'Insulin increases central apolipoprotein E levels as revealed by an improved technique for collection of cerebrospinal fluid from rats', Journal of Neuroscience Methods, 209, pp. 106 - 112, http://dx.doi.org/10.1016/j.jneumeth.2012.05.034
    Journal articles | 2012
    MacDonald L; Begg D; Weisinger RS; Kent S, 2012, 'Calorie restricted rats do not increase metabolic rate post-LPS, but do seek out warmer ambient temperatures to behaviourally induce a fever', Physiology and Behavior, 107, pp. 762 - 772, http://dx.doi.org/10.1016/j.physbeh.2012.06.009
    Journal articles | 2012
    Mul JD; Begg DP; Alsters SIM; van Haaften G; Duran KJ; D'Alessio DA; le Roux CW; Woods SC; Sandoval DA; Blakemore AIF; Cuppen E; van Haelst MM; Seeley RJ, 2012, 'Effect of Vertical sleeve gastrectomy in melanocortin receptor 4-deficient rats', American Journal of Physiology - Endocrinology and Metabolism, 303, pp. e103 - e110, http://dx.doi.org/10.1152/ajpendo.00159.2012
    Journal articles | 2012
    Premaratna SD; Manickam E; Begg DP; Rayment DJ; Hafandi A; Jois M; Cameron-Smith D; Weisinger RS, 2012, 'Angiotensin-converting enzyme inhibition reverses diet-induced obesity, insulin resistance and inflammation in C57BL/6J mice', International Journal of Obesity, 36, pp. 233 - 243, http://dx.doi.org/10.1038/ijo.2011.95
    Journal articles | 2012
    Yoshimichi G; Lo CC; Tamashiro KLK; Ma L; Lee DM; Begg DP; Liu M; Sakai RR; Woods SC; Yoshimatsu H; Tso P, 2012, 'Effect of peripheral administration of cholecystokinin on food intake in apolipoprotein AIV knockout mice', American Journal of Physiology - Gastrointestinal and Liver Physiology, 302, http://dx.doi.org/10.1152/ajpgi.00325.2010
    Journal articles | 2011
    Weisinger RS; Stahl L; Begg DP; Jois M; Desai A; Smythe J, 2011, 'Molasses extract decreases diet-induced obesity', Appetite, 57, pp. S46 - S46, http://dx.doi.org/10.1016/j.appet.2011.05.291
    Journal articles | 2010
    Begg DP; Sinclair AJ; Stahl LA; Garg ML; Jois M; Weisinger RS, 2010, 'Dietary protein level interacts with ω-3 polyunsaturated fatty acid deficiency to induce hypertension', American Journal of Hypertension, 23, pp. 125 - 128, http://dx.doi.org/10.1038/ajh.2009.198
    Journal articles | 2010
    Begg DP; Sinclair AJ; Stahl LA; Premaratna SD; Hafandi A; Jois M; Weisinger RS, 2010, 'Hypertension induced by-3 polyunsaturated fatty acid deficiency is alleviated by α-linolenic acid regardless of dietary source', Hypertension Research, 33, pp. 808 - 813, http://dx.doi.org/10.1038/hr.2010.84
    Journal articles | 2010
    Begg DP; Sinclair AJ; Weisinger RS, 2010, 'Dietary omega-3 fatty acid deficiency, hypertension and the renin–angiotensin system', Appetite, 54, pp. 634 - 634, http://dx.doi.org/10.1016/j.appet.2010.04.021
    Journal articles | 2010
    Kaur G; Begg DP; Barr D; Garg M; Cameron-Smith D; Sinclair AJ, 2010, 'Short-term docosapentaenoic acid (22:5n-3) supplementation increases tissue docosapentaenoic acid, DHA and EPA concentrations in rats', British Journal of Nutrition, 103, pp. 32 - 37, http://dx.doi.org/10.1017/S0007114509991334
    Journal articles | 2010
    Weisinger RS; Armitage JA; Chen N; Begg DP; Mathai ML; Jayasooriya AP; Sinclair AJ; Weisinger HS, 2010, 'Sodium appetite in adult rats following ω-3 polyunsaturated fatty acid deficiency in early development', Appetite, 55, pp. 393 - 397, http://dx.doi.org/10.1016/j.appet.2010.07.006
    Journal articles | 2010
    Weisinger RS; Begg DP; Bennett G; Jois M, 2010, 'Mechanisms involved in reduction of diet-induced obesity by captopril in C57BL/6J mice', Appetite, 54, pp. 681 - 681, http://dx.doi.org/10.1016/j.appet.2010.04.209
    Journal articles | 2009
    Begg DP; Sinclair AJ; Weisinger RS, 2009, 'Dietary ω-3 polyunsaturated fatty acids (PUFA) eliminate thirst deficits associated with aging', Appetite, 52, pp. 819 - 819, http://dx.doi.org/10.1016/j.appet.2009.04.021
    Journal articles | 2009
    Chen N; Bezzina R; Hinch E; Lewandowski PA; Cameron-Smith D; Mathai ML; Jois M; Sinclair AJ; Begg DP; Wark JD; Weisinger HS; Weisinger RS, 2009, 'Green tea, black tea, and epigallocatechin modify body composition, improve glucose tolerance, and differentially alter metabolic gene expression in rats fed a high-fat diet', Nutrition Research, 29, pp. 784 - 793, http://dx.doi.org/10.1016/j.nutres.2009.10.003
    Journal articles | 2009
    Hallam KT; Begg DP; Olver JS; Norman TR, 2009, 'Abnormal dose-response melatonin suppression by light in bipolar type i patients compared with healthy adult subjects', Acta Neuropsychiatrica, 21, pp. 246 - 255, http://dx.doi.org/10.1111/j.1601-5215.2009.00416.x
    Journal articles | 2009
    Weisinger RS; Begg DP; Denton DA; Findlay ALR; Kennedy GA; Purcell B; Walker LL; Blair-West JR, 2009, 'Endocrine and ingestive behavioral responses to fluid deprivation in sheep chronically exposed to ethanol', Physiology and Behavior, 96, pp. 637 - 645, http://dx.doi.org/10.1016/j.physbeh.2008.12.021
    Journal articles | 2009
    Weisinger RS; Begg DP; Jois M; Guidice B; Kannar D; Kitchen B, 2009, 'Sugarcane-derived polyphenols decrease diet-induced obesity', Appetite, 52, pp. 864 - 864, http://dx.doi.org/10.1016/j.appet.2009.04.203
    Journal articles | 2009
    Weisinger RS; Begg DP; Jois M, 2009, 'Antagonists of the renin-angiotensin system and the prevention of obesity', Current Opinion in Investigational Drugs, 10, pp. 1069 - 1077
    Journal articles | 2009
    Weisinger RS; Stanley TK; Begg DP; Weisinger HS; Spark KJ; Jois M, 2009, 'Angiotensin converting enzyme inhibition lowers body weight and improves glucose tolerance in C57BL/6J mice maintained on a high fat diet', Physiology and Behavior, 98, pp. 192 - 197, http://dx.doi.org/10.1016/j.physbeh.2009.05.009
    Journal articles | 2008
    Begg DP; Mathai ML; McKinley MJ; Frappell PB; Kent S, 2008, 'Central nitric oxide synthase inhibition restores behaviorally mediated lipopolysaccharide induced fever in near-term rats', Physiology and Behavior, 94, pp. 630 - 634, http://dx.doi.org/10.1016/j.physbeh.2008.03.022
    Journal articles | 2008
    Begg DP; Weisinger RS, 2008, 'The role of adrenal or testicular hormones in voluntary ethanol and NaCl intake of crowded and individually housed rats', Physiology and Behavior, 93, pp. 408 - 413, http://dx.doi.org/10.1016/j.physbeh.2007.09.007
    Journal articles | 2008
    Hallam KT; Begg DP; Olver JS; Norman TR, 2008, 'An investigation of the effect of immediate and extended release venlafaxine on nocturnal melatonin and cortisol release in healthy adult volunteers', Human Psychopharmacology, 23, pp. 129 - 137, http://dx.doi.org/10.1002/hup.913
    Journal articles | 2008
    Jayasooriya AP; Begg DP; Chen N; Mathai ML; Sinclair AJ; Wilkinson-Berka J; Wark JD; Weisinger HS; Weisinger RS, 2008, 'Omega-3 polyunsaturated fatty acid supplementation reduces hypertension in TGR(mRen-2)27 rats', Prostaglandins Leukotrienes and Essential Fatty Acids, 78, pp. 67 - 72, http://dx.doi.org/10.1016/j.plefa.2007.11.001
    Journal articles | 2008
    Jayasooriya AP; Mathai ML; Walker LL; Begg DP; Denton DA; Cameron-Smith D; Egan GF; McKinley MJ; Rodger PD; Sinclair AJ; Wark JD; Weisinger HS; Jois M; Weisinger RS, 2008, 'Mice lacking angiotensin-converting enzyme have increased energy expenditure, with reduced fat mass and improved glucose clearance', Proceedings of the National Academy of Sciences of the United States of America, 105, pp. 6531 - 6536, http://dx.doi.org/10.1073/pnas.0802690105
    Journal articles | 2008
    Stahl LA; Begg DP; Weisinger RS; Sinclair AJ, 2008, 'The role of omega-3 fatty acids in mood disorders', Current Opinion in Investigational Drugs, 9, pp. 57 - 64
    Journal articles | 2008
    Weisinger HS; Begg DP; Egan GF; Jayasooriya AP; Lie F; Mathai ML; Sinclair AJ; Wark JD; Weisinger RS, 2008, 'Angiotensin converting enzyme inhibition from birth reduces body weight and body fat in Sprague-Dawley rats', Physiology and Behavior, 93, pp. 820 - 825, http://dx.doi.org/10.1016/j.physbeh.2007.11.046
    Journal articles | 2007
    Attar-Bashi NM; Weisinger RS; Begg DP; Li D; Sinclair AJ, 2007, 'Failure of conjugated linoleic acid supplementation to enhance biosynthesis of docosahexaenoic acid from α-linolenic acid in healthy human volunteers', Prostaglandins Leukotrienes and Essential Fatty Acids, 76, pp. 121 - 130, http://dx.doi.org/10.1016/j.plefa.2006.11.002
    Journal articles | 2007
    Begg DP; Kent S; McKinley MJ; Mathai ML, 2007, 'Suppression of endotoxin-induced fever in near-term pregnant rats is mediated by brain nitric oxide', American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 292, http://dx.doi.org/10.1152/ajpregu.00032.2007
    Journal articles | 2007
    Sinclair AJ; Begg D; Mathai M; Weisinger RS, 2007, 'Omega 3 fatty acids and the brain: Review of studies in depression', Asia Pacific Journal of Clinical Nutrition, 16, pp. 391 - 397
    Journal articles | 2007
    Weisinger RS; Begg DP; Chen N; Jois M; Mathai ML; Sinclair AJ, 2007, 'The problem of obesity: Is there a role for antagonists of the renin-angiotensin system?', Asia Pacific Journal of Clinical Nutrition, 16, pp. 359 - 367
    Journal articles | 2006
    Hallam KT; Olver JS; Chambers V; Begg DP; McGrath C; Norman TR, 2006, 'The heritability of melatonin secretion and sensitivity to bright nocturnal light in twins', Psychoneuroendocrinology, 31, pp. 867 - 875, http://dx.doi.org/10.1016/j.psyneuen.2006.04.004
    Journal articles | 2005
    Begg DP; Hallam KT; Norman TR, 2005, 'Attenuation of benzodiazepine withdrawal anxiety in the rat by serotonin antagonists', Behavioural Brain Research, 161, pp. 286 - 290, http://dx.doi.org/10.1016/j.bbr.2005.02.027
  • Preprints | 2022
    Amanda Tan RP; Kozlova I; Su F; Sah S; Keable R; Hagan W; Bustamante S; Du X; Osborne B; Turner N; Clemens K; Begg D; Phelps E; Yang H; Leshchyns’ka I; Sytnyk V, 2022, Neuronal growth regulator 1 (NEGR1) promotes synaptic targeting of glutamic acid decarboxylase 65 (GAD65), http://dx.doi.org/10.1101/2022.02.08.479601
    Preprints | 2020
    Le JT; Watson P; Begg D; Albertella L; Le Pelley M, 2020, Physiological and subjective validation of a novel stress procedure: The Simple Singing Stress Procedure, http://dx.doi.org/10.31234/osf.io/ufh7c
    Conference Papers | 2014
    Mul JD; Magrisso J; Loyd CM; Begg DP; Haas MK; Woods SC; Sandoval DA; Seeley RJ; Goodyear LJ; Obici S, 2014, 'Voluntary Exercise Attenuates MC4R-associated Metabolic Syndrome and Reveals Dopamine Signaling Dysregulation', in DIABETES, AMER DIABETES ASSOC, pp. A182 - A183, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000359481601048&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2011
    Hallam KT; Begg DP; Olver JS; Norman TR, 2011, 'An investigation of melatonin sensitivity to light as a potential endophenotypic marker of bipolar affective disorder', in BIPOLAR DISORDERS, WILEY-BLACKWELL, PA, Pittsburgh, pp. 53 - 53, presented at 9th International Conference on Bipolar Disorder, PA, Pittsburgh, 09 June 2011 - 11 June 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000300102400115&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2010
    Hafandi A; Begg DP; Sinclair AJ; Mathai ML; Weisinger RS, 2010, 'HYPERTENSION OF 3(rd) GENERATION omega-3 FATTY ACID-DEFICIENT MICE', in HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, AUSTRALIA, Melbourne, pp. 124 - 124, presented at 32nd Annual Scientific Meeting of the High Blood Pressure Research Council of Australia, AUSTRALIA, Melbourne, 01 December 2010 - 03 December 2010, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000291655000066&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2009
    Begg DP; Sinclair AJ; Shi JR; Weisinger RS, 2009, 'HYPERTENSION INDUCED BY ohm-3 FATTY ACID DEFICIENCY: THE ROLE OF THE RENIN-ANGIOTENSIN SYSTEM', in HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, AUSTRALIA, Sydney, pp. 1495 - 1495, presented at 31st Annual Scientific Meeting of the High-Blood-Pressure-Research-Council-of-Australia, AUSTRALIA, Sydney, 01 December 2009 - 03 December 2009, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000277848100048&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2009
    Hafandi A; Rayner V; Begg DP; Sinclair AJ; Jois M; Weisinger RS, 2009, 'DOES SELENIUM DEFICIENCY EXPOSE THE HYPERTENSIVE EFFECT OF AN OMEGA-3 FATTY ACID-DEFICIENT DIET?', in HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, AUSTRALIA, Sydney, pp. 1494 - 1494, presented at 31st Annual Scientific Meeting of the High-Blood-Pressure-Research-Council-of-Australia, AUSTRALIA, Sydney, 01 December 2009 - 03 December 2009, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000277848100040&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2007
    Weisinger RS; Stahl L; Begg D; Jois M; Mathai ML; Williams J; Sinclair AJ; Kannar D, 2007, 'Sugarcane-derived polyphenols decrease diet-induced obesity', in ANNALS OF NUTRITION AND METABOLISM, KARGER, pp. 372 - 373, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000248185401450&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2004
    Begg DP; Norman TR, 2004, 'Benzodiazepine withdrawal in the rat and treatment of the associated anxiety with 5-HT2 antagonists', in INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, CAMBRIDGE UNIV PRESS, FRANCE, Paris, pp. S144 - S144, presented at 24th CINP Congress, FRANCE, Paris, 20 June 2004 - 24 June 2004, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000224663000538&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1