Conjoint Professor

Professor Diane Fatkin

medicine-health
St Vincent's Clinical School

Research Interests:
The principal focus of our research is identification of disease-causing genes and elucidation of pathogenetic mechanisms in inherited disorders of the heart's contraction and rhythm. Our clinical studies focus on gene discovery studies in families with dilated cardiomyopathy and/or atrial fibrillation. The functional consequences of DNA variants identified in families are evaluated using in vitro techniques as well as in mouse and zebrafish models.

Broad Research Areas:
Cardiology and Vascular Disease

Qualifications:
BSc (Med), MB BS Syd, FRACP, MD UNSW

Society Memberships & Professional Activities:
Fellow, Cardiac Society of Australia and New Zealand, Member, Basic Sciences Council, American Heart Association

Specific Research Keywords:
Molecular Cardiology, Cardiomyopathy, Genetics, Arrhythmias, Atrial fibrillation

Phone
(02) 9295 8618
Location
Victor Chang Cardiac Research Institute Lowy Packer Building 405 Liverpool St, Darlinghurst NSW 2010 Australia St Vincent's Clinical School, UNSW Medicine, UNSW Sydney

Publications

  • Book Chapters | 2020
    Professor Diane Fatkin
    Paranal RM; Teekakirikul P; Ho CY; Fatkin D; Seidman CE, 2020, '2 Genetic Cardiomyopathies', in Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics, pp. 77 - 114, http://dx.doi.org/10.1016/b978-0-12-812532-8.00002-1
    Book Chapters | 2019
    Professor Diane Fatkin
    Paranal RM; Teekakirikul P; Ho CY; Fatkin D; Seidman CE, 2019, 'Genetic cardiomyopathies', in Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics: Cardiovascular, Respiratory, and Gastrointestinal Disorders, pp. 77 - 114, http://dx.doi.org/10.1016/B978-0-12-812532-8.00002-1
    Book Chapters | 2007
    Professor Diane Fatkin
    Fatkin D; Seidman JG; Seidman CE, 2007, 'Hypertrophic Cardiomyopathy', in Cardiovascular Medicine, Springer London, pp. 1261 - 1284, http://dx.doi.org/10.1007/978-1-84628-715-2_59
    Book Chapters |
    Professor Diane Fatkin
    Fatkin D, 'Familial Dilated Cardiomyopathy', in Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine, Springer Berlin Heidelberg, pp. 550 - 557, http://dx.doi.org/10.1007/3-540-29623-9_2080
  • Journal articles | 2021
    Professor Diane Fatkin
    Pineda S; Nikolova-Krstevski V; Leimena C; Atkinson AJ; Altekoester AK; Cox CD; Jacoby A; Huttner IG; Ju YK; Soka M; Ohanian M; Trivedi G; Kalvakuri S; Birker K; Johnson R; Molenaar P; Kuchar D; Allen DG; Van Helden DF; Harvey RP; Hill AP; Bodmer R; Vogler G; Dobrzynski H; Ocorr K; Fatkin D, 2021, 'Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, KCa1.1, in Sinus Node Function and Arrhythmia Risk', Circulation: Genomic and Precision Medicine, pp. 230 - 242, http://dx.doi.org/10.1161/CIRCGEN.120.003144
    Journal articles | 2021
    Professor Diane Fatkin
    Peters S; Johnson R; Zentner D; James P; Kalman JM; Fatkin D, 2021, 'Long-Term Efficacy and Safety of Sodium Channel Antagonists in Patients With p.R222Q SCN5A-Related Arrhythmic Dilated Cardiomyopathy', JACC: Clinical Electrophysiology, vol. 7, pp. 126 - 128, http://dx.doi.org/10.1016/j.jacep.2020.09.023
    Journal articles | 2021
    Professor Diane Fatkin
    Lacaze P; Sebra R; Riaz M; Ingles J; Tiller J; Thompson BA; James PA; Fatkin D; Semsarian C; Reid CM; Tonkin AM; Winship I; Schadt E; McNeil JJ, 2021, 'Genetic variants associated with inherited cardiovascular disorders among 13,131 asymptomatic older adults of European descent', npj Genomic Medicine, vol. 6, http://dx.doi.org/10.1038/s41525-021-00211-x
    Journal articles | 2021
    Professor Diane Fatkin
    Taliun D; Harris DN; Kessler MD; Carlson J; Szpiech ZA; Torres R; Taliun SAG; Corvelo A; Gogarten SM; Kang HM; Pitsillides AN; LeFaive J; Lee SB; Tian X; Browning BL; Das S; Emde AK; Clarke WE; Loesch DP; Shetty AC; Blackwell TW; Smith AV; Wong Q; Liu X; Conomos MP; Bobo DM; Aguet F; Albert C; Alonso A; Ardlie KG; Arking DE; Aslibekyan S; Auer PL; Barnard J; Barr RG; Barwick L; Becker LC; Beer RL; Benjamin EJ; Bielak LF; Blangero J; Boehnke M; Bowden DW; Brody JA; Burchard EG; Cade BE; Casella JF; Chalazan B; Chasman DI; Chen YDI; Cho MH; Choi SH; Chung MK; Clish CB; Correa A; Curran JE; Custer B; Darbar D; Daya M; de Andrade M; DeMeo DL; Dutcher SK; Ellinor PT; Emery LS; Eng C; Fatkin D; Fingerlin T; Forer L; Fornage M; Franceschini N; Fuchsberger C; Fullerton SM; Germer S; Gladwin MT; Gottlieb DJ; Guo X; Hall ME; He J; Heard-Costa NL; Heckbert SR; Irvin MR; Johnsen JM; Johnson AD; Kaplan R; Kardia SLR; Kelly T; Kelly S; Kenny EE; Kiel DP; Klemmer R; Konkle BA; Kooperberg C; Köttgen A; Lange LA; Lasky-Su J; Levy D; Lin X; Lin KH; Liu C; Loos RJF, 2021, 'Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program', Nature, vol. 590, pp. 290 - 299, http://dx.doi.org/10.1038/s41586-021-03205-y
    Journal articles | 2021
    Professor Diane Fatkin
    Fatkin D; Calkins H; Elliott P; James CA; Peters S; Kovacic JC, 2021, 'Contemporary and Future Approaches to Precision Medicine in Inherited Cardiomyopathies: JACC Focus Seminar 3/5', Journal of the American College of Cardiology, vol. 77, pp. 2551 - 2572, http://dx.doi.org/10.1016/j.jacc.2020.12.072
    Journal articles | 2021
    Professor Diane Fatkin
    Iismaa SE; Hesselson S; McGrath-Cadell L; Muller DW; Fatkin D; Giannoulatou E; Kovacic J; Graham RM, 2021, 'Spontaneous Coronary Artery Dissection and Fibromuscular Dysplasia: Vasculopathies With a Predilection for Women', Heart Lung and Circulation, vol. 30, pp. 27 - 35, http://dx.doi.org/10.1016/j.hlc.2020.05.110
    Journal articles | 2021
    Professor Diane Fatkin
    Giudicessi JR; Ackerman MJ; Fatkin D; Kovacic JC, 2021, 'Precision Medicine Approaches to Cardiac Arrhythmias: JACC Focus Seminar 4/5', Journal of the American College of Cardiology, vol. 77, pp. 2573 - 2591, http://dx.doi.org/10.1016/j.jacc.2021.03.325
    Journal articles | 2021
    Professor Diane Fatkin
    Yu ZY; Gong H; Wu J; Dai Y; Kesteven SH; Fatkin D; Martinac B; Graham RM; Feneley MP, 2021, 'Cardiac Gq Receptors and Calcineurin Activation Are Not Required for the Hypertrophic Response to Mechanical Left Ventricular Pressure Overload', Frontiers in Cell and Developmental Biology, vol. 9, pp. 639509, http://dx.doi.org/10.3389/fcell.2021.639509
    Journal articles | 2021
    Professor Diane Fatkin
    Guo Y; Merten AL; Schöler U; Yu ZY; Cvetkovska J; Fatkin D; Feneley MP; Martinac B; Friedrich O, 2021, 'In vitro cell stretching technology (IsoStretcher) as an approach to unravel Piezo1-mediated cardiac mechanotransduction', Progress in Biophysics and Molecular Biology, vol. 159, pp. 22 - 33, http://dx.doi.org/10.1016/j.pbiomolbio.2020.07.003
    Journal articles | 2021
    Professor Diane Fatkin
    McGrath-Cadell L; Iismaa SE; Hesselson S; Muller DW; Fatkin D; Giannoulatou E; Kovacic JC; Graham RM, 2021, 'Recent Updates on Spontaneous Coronary Artery Dissection and Fibromuscular Dysplasia', International Journal of Integrative Cardiology, vol. 3, http://dx.doi.org/10.47275/2690-862x-121
    Journal articles | 2021
    Professor Diane Fatkin
    Santiago CF; Huttner IG; Fatkin D, 2021, 'Mechanisms of TTNtv-related dilated cardiomyopathy: Insights from zebrafish models', Journal of Cardiovascular Development and Disease, vol. 8, pp. 1 - 18, http://dx.doi.org/10.3390/jcdd8020010
    Journal articles | 2020
    Professor Diane Fatkin
    Wong GR; Nalliah CJ; Lee G; Voskoboinik A; Prabhu S; Parameswaran R; Sugumar H; Anderson RD; Ling LH; McLellan A; Johnson R; Sanders P; Kistler PM; Fatkin D; Kalman JM, 2020, 'Genetic Susceptibility to Atrial Fibrillation Is Associated With Atrial Electrical Remodeling and Adverse Post-Ablation Outcome', JACC: Clinical Electrophysiology, vol. 6, pp. 1509 - 1521, http://dx.doi.org/10.1016/j.jacep.2020.05.031
    Journal articles | 2020
    Professor Diane Fatkin
    Peters S; Johnson R; Birch S; Zentner D; Hershberger RE; Fatkin D, 2020, 'Familial Dilated Cardiomyopathy', Heart Lung and Circulation, vol. 29, pp. 566 - 574, http://dx.doi.org/10.1016/j.hlc.2019.11.018
    Journal articles | 2020
    Professor Diane Fatkin
    Fatkin D; Johnson R, 2020, 'Variants of Uncertain Significance and “Missing Pathogenicity”', Journal of the American Heart Association, vol. 9, pp. e015588, http://dx.doi.org/10.1161/JAHA.119.015588
    Journal articles | 2020
    Professor Diane Fatkin
    Akhtar MM; Lorenzini M; Cicerchia M; Ochoa JP; Hey TM; Sabater Molina M; Restrepo-Cordoba MA; Dal Ferro M; Stolfo D; Johnson R; Larrañaga-Moreira JM; Robles-Mezcua A; Rodriguez-Palomares JF; Casas G; Peña-Peña ML; Lopes LR; Gallego-Delgado M; Franaszczyk M; Laucey G; Rangel-Sousa D; Basurte M; Palomino-Doza J; Villacorta E; Bilinska Z; Limeres Freire J; Garcia Pinilla JM; Barriales-Villa R; Fatkin D; Sinagra G; Garcia-Pavia P; Gimeno JR; Mogensen J; Monserrat L; Elliott PM, 2020, 'Clinical phenotypes and prognosis of dilated cardiomyopathy caused by truncating variants in the TTN Gene', Circulation: Heart Failure, vol. 13, pp. 496 - 508, http://dx.doi.org/10.1161/CIRCHEARTFAILURE.119.006832
    Journal articles | 2020
    Professor Diane Fatkin
    Ntalla I; Weng LC; Cartwright JH; Hall AW; Sveinbjornsson G; Tucker NR; Choi SH; Chaffin MD; Roselli C; Barnes MR; Mifsud B; Warren HR; Hayward C; Marten J; Cranley JJ; Concas MP; Gasparini P; Boutin T; Kolcic I; Polasek O; Rudan I; Araujo NM; Lima-Costa MF; Ribeiro ALP; Souza RP; Tarazona-Santos E; Giedraitis V; Ingelsson E; Mahajan A; Morris AP; Del Greco M F; Foco L; Gögele M; Hicks AA; Cook JP; Lind L; Lindgren CM; Sundström J; Nelson CP; Riaz MB; Samani NJ; Sinagra G; Ulivi S; Kähönen M; Mishra PP; Mononen N; Nikus K; Caulfield MJ; Dominiczak A; Padmanabhan S; Montasser ME; O’Connell JR; Ryan K; Shuldiner AR; Aeschbacher S; Conen D; Risch L; Thériault S; Hutri-Kähönen N; Lehtimäki T; Lyytikäinen LP; Raitakari OT; Barnes CLK; Campbell H; Joshi PK; Wilson JF; Isaacs A; Kors JA; van Duijn CM; Huang PL; Gudnason V; Harris TB; Launer LJ; Smith AV; Bottinger EP; Loos RJF; Nadkarni GN; Preuss MH; Correa A; Mei H; Wilson J; Meitinger T; Müller-Nurasyid M; Peters A; Waldenberger M; Mangino M; Spector TD; Rienstra M; van de Vegte YJ; van der Harst P; Verweij N; Kääb S; Schramm K; Sinner MF; Strauch K; Cutler MJ; Fatkin D; London B; Olesen M; Roden DM, 2020, 'Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction', Nature Communications, vol. 11, pp. 2542, http://dx.doi.org/10.1038/s41467-020-15706-x
    Journal articles | 2020
    Professor Diane Fatkin
    Bart NK; Thomas L; Korczyk D; Atherton JJ; Stewart GJ; Fatkin D, 2020, 'Amyloid Cardiomyopathy', Heart Lung and Circulation, vol. 29, pp. 575 - 583, http://dx.doi.org/10.1016/j.hlc.2019.11.019
    Journal articles | 2020
    Professor Diane Fatkin
    Situ Y; Baric J; Han W; Law M; Fatkin D; Graham R, 2020, '055 Prevalence and Patient Awareness of Cardiovascular Risk Factors in a Community-Based Australian Cohort', Heart, Lung and Circulation, vol. 29, pp. S62 - S62, http://dx.doi.org/10.1016/j.hlc.2020.09.062
    Journal articles | 2020
    Professor Diane Fatkin
    Carss KJ; Baranowska AA; Armisen J; Webb TR; Hamby SE; Premawardhana D; Al-Hussaini A; Wood A; Wang Q; Deevi SVV; Vitsios D; Lewis SH; Kotecha D; Bouatia-Naji N; Hesselson S; Iismaa SE; Tarr I; McGrath-Cadell L; Muller DW; Dunwoodie SL; Fatkin D; Graham RM; Giannoulatou E; Samani NJ; Petrovski S; Haefliger C; Adlam D, 2020, 'Spontaneous Coronary Artery Dissection: Insights on Rare Genetic Variation from Genome Sequencing', Circulation: Genomic and Precision Medicine, pp. 630 - 639, http://dx.doi.org/10.1161/CIRCGEN.120.003030
    Journal articles | 2020
    Professor Diane Fatkin
    Kessler MD; Loesch DP; Perry JA; Heard-Costa NL; Taliun D; Cade BE; Wang H; Daya M; Ziniti J; Datta S; Celedón JC; Soto-Quiros ME; Avila L; Weiss ST; Barnes K; Redline SS; Vasan RS; Johnson AD; Mathias RA; Hernandez R; Wilson JG; Nickerson DA; Abecasis G; Browning SR; Zöllner S; O'Connell JR; Mitchell BD; National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium ; TOPMed Population Genetics Working Group ; O'Connor TD, 2020, 'De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.', Proc Natl Acad Sci U S A, vol. 117, pp. 2560 - 2569, http://dx.doi.org/10.1073/pnas.1902766117
    Journal articles | 2020
    Professor Diane Fatkin
    Gladding PA; Legget M; Fatkin D; Larsen P; Doughty R, 2020, 'Polygenic Risk Scores in Coronary Artery Disease and Atrial Fibrillation', Heart Lung and Circulation, vol. 29, pp. 634 - 640, http://dx.doi.org/10.1016/j.hlc.2019.12.004
    Journal articles | 2020
    Professor Diane Fatkin
    Gray B; Semsarian C; Fatkin D; Ingles J; Atherton JJ; Davis AM; Sanders P; Pachter N; Skinner JR; Stiles MK, 2020, 'Patients With Genetic Heart Disease and COVID-19: A Cardiac Society of Australia and New Zealand (CSANZ) Consensus Statement', Heart Lung and Circulation, vol. 29, pp. e85 - e87, http://dx.doi.org/10.1016/j.hlc.2020.04.006
    Journal articles | 2020
    Professor Diane Fatkin
    Santiago C; Chand R; Humphreys D; Young P; Ward A; Huttner I; Fatkin D, 2020, '002 Titin Truncation Provides a Sensitised Template for Cardio-Depressant Effects of Alcohol', Heart, Lung and Circulation, vol. 29, pp. S37 - S38, http://dx.doi.org/10.1016/j.hlc.2020.09.009
    Journal articles | 2019
    Professor Diane Fatkin
    Horvat C; Johnson R; Lam L; Munro J; Mazzarotto F; Roberts AM; Herman DS; Parfenov M; Haghighi A; McDonough B; DePalma SR; Keogh AM; Macdonald PS; Hayward CS; Roberts A; Barton PJR; Felkin LE; Giannoulatou E; Cook SA; Seidman JG; Seidman CE; Fatkin D, 2019, 'A gene-centric strategy for identifying disease-causing rare variants in dilated cardiomyopathy', Genetics in Medicine, vol. 21, pp. 133 - 143, http://dx.doi.org/10.1038/s41436-018-0036-2
    Journal articles | 2019
    Professor Diane Fatkin
    Minoche AE; Horvat C; Johnson R; Gayevskiy V; Morton SU; Drew AP; Woo K; Statham AL; Lundie B; Bagnall RD; Ingles J; Semsarian C; Seidman JG; Seidman CE; Dinger ME; Cowley MJ; Fatkin D, 2019, 'Genome sequencing as a first-line genetic test in familial dilated cardiomyopathy', Genetics in Medicine, vol. 21, pp. 650 - 662, http://dx.doi.org/10.1038/s41436-018-0084-7
    Journal articles | 2019
    Professor Diane Fatkin
    Fatkin D; Huttner IG; Johnson R, 2019, 'Genetics of atrial cardiomyopathy', Current Opinion in Cardiology, vol. 34, pp. 275 - 281, http://dx.doi.org/10.1097/HCO.0000000000000610
    Journal articles | 2019
    Professor Diane Fatkin
    Johnson R; Peters S; Ingles J; Correnti G; Ingrey A; Mountain H; Zentner D; Thompson T; Oates E; Ronan A; Pachter N; Haan E; Van Spaendonck-Zwarts K; Semsarian C; McGaughran J; Atherton J; James P; Fatkin D, 2019, 'Penetrance of Dilated Cardiomyopathy in Families with Truncating TTN Variants: a National Perspective', Heart, Lung and Circulation, vol. 28, pp. S140 - S140, http://dx.doi.org/10.1016/j.hlc.2019.06.019
    Journal articles | 2019
    Professor Diane Fatkin
    Wong G; Nalliah C; Voskoboinik A; Lee G; Prabhu S; Sugumar H; Parameswaran R; Anderson R; McLellan A; Ling L; Morton J; Johnson R; Kistler P; Fatkin D; Kalman J, 2019, 'Genetic Susceptibility to Atrial Fibrillation at the chr 4q25 Locus is Associated with Left Atrial Electrical Remodelling', Heart, Lung and Circulation, vol. 28, pp. S132 - S132, http://dx.doi.org/10.1016/j.hlc.2019.06.003
    Journal articles | 2019
    Professor Diane Fatkin
    Adlam D; Olson TM; Combaret N; Kovacic JC; Iismaa SE; Al-Hussaini A; O'Byrne MM; Bouajila S; Georges A; Mishra K; Braund PS; d'Escamard V; Huang S; Margaritis M; Nelson CP; de Andrade M; Kadian-Dodov D; Welch CA; Mazurkiewicz S; Jeunemaitre X; Motreff P; Belle L; Dupouy P; Barnay P; Meneveau N; Gilard M; Rioufol G; Range G; Brunel P; Delarche N; Filippi E; Le Bivic L; Harbaoui B; Benamer H; Cayla G; Varenne O; Manzo-Silberman SP; Silvain J; Spaulding C; Caussin C; Gerbaud E; Valy Y; Koning R; Lhermusier T; Champin S; Salengro E; Fluttaz A; Zabalawi A; Cottin Y; Teiger E; Saint-Etienne C; Ducrocq G; Marliere S; Boiffard E; Aubry P; Georges JL; Bresson D; De Poli F; Karrillon G; Roule V; Bali L; Valla M; Gerbay A; Houpe D; Dubreuil O; Monnier A; Mayaud N; Manchuelle A; Commeau P; Bedossa M; Wong CMY; Giannoulatou E; Sweeting M; Muller D; Wood A; McGrath-Cadell L; Fatkin D; Dunwoodie SL; Harvey R; Holloway C; Empana JP; Jouven X; Nikpay M; Goel A; Won HH; Hall LM; Willenborg C; Kanoni S; Saleheen D; Kyriakou T; Hopewell JC; Webb TR; Zeng L; Dehghan A; Alver M; Armasu SM; Auro K; Bjonnes A; Chasman DI; Chen S, 2019, 'Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection', Journal of the American College of Cardiology, vol. 73, pp. 58 - 66, http://dx.doi.org/10.1016/j.jacc.2018.09.085
    Journal articles | 2019
    Professor Diane Fatkin
    McGrath-Cadell L; Hesselson S; Iismaa S; Mishra K; Wong C; Fatkin D; Dunwoodie S; Harvey R; Holloway C; Muller D; Giannoulatou E; Graham R, 2019, 'Familial Clustering of Spontaneous Coronary Artery Dissection', Heart, Lung and Circulation, vol. 28, pp. S330 - S330, http://dx.doi.org/10.1016/j.hlc.2019.06.454
    Journal articles | 2019
    Professor Diane Fatkin
    McGrath-Cadell L; Hesselson S; Iismaa SE; Mishra K; Wong CMY; Fatkin D; Dunwoodie SL; Harvey R; Holloway CJ; Muller DWM; Giannoulatou E; Graham RM, 2019, 'P5540Familial clustering of spontaneous coronary artery dissection', European Heart Journal, vol. 40, http://dx.doi.org/10.1093/eurheartj/ehz746.0486
    Journal articles | 2019
    Professor Diane Fatkin
    Peters S; Kumar S; Elliott P; Kalman JM; Fatkin D, 2019, 'Arrhythmic Genotypes in Familial Dilated Cardiomyopathy: Implications for Genetic Testing and Clinical Management', Heart Lung and Circulation, vol. 28, pp. 31 - 38, http://dx.doi.org/10.1016/j.hlc.2018.09.010
    Journal articles | 2019
    Professor Diane Fatkin
    Fatkin D; Huttner IG; Kovacic JC; Seidman JG; Seidman CE, 2019, 'Precision Medicine in the Management of Dilated Cardiomyopathy: JACC State-of-the-Art Review', Journal of the American College of Cardiology, vol. 74, pp. 2921 - 2938, http://dx.doi.org/10.1016/j.jacc.2019.10.011
    Journal articles | 2019
    Professor Diane Fatkin
    Burns C; Hoorntje E; Corden B; Parikh V; Thompson T; Marsili L; Gray B; Reuter C; Bagnall R; Correnti G; Duflou J; Fatkin D; Fietz M; Haan E; Lam L; Goldblatt J; McCarthy H; Pachter N; Vohra J; Whiffin N; Zentner D; Wheeler M; Ashley E; Semsarian C; Ware J; van Tintelen P; Ingles J, 2019, 'Truncating Variants in the Desmoplakin Gene Cause a Distinct Arrhythmogenic Cardiomyopathy', Heart, Lung and Circulation, vol. 28, pp. S134 - S134, http://dx.doi.org/10.1016/j.hlc.2019.06.007
    Journal articles | 2018
    Professor Diane Fatkin
    Fatkin D, 2018, 'ETV1: A new player in atrial remodeling', Circulation Research, vol. 123, pp. 515 - 517, http://dx.doi.org/10.1161/CIRCRESAHA.118.313606
    Journal articles | 2018
    Professor Diane Fatkin
    Fatkin D; Cox CD; Huttner IG; Martinac B, 2018, 'Is There a Role for Genes in Exercise-Induced Atrial Cardiomyopathy?', Heart Lung and Circulation, vol. 27, pp. 1093 - 1098, http://dx.doi.org/10.1016/j.hlc.2018.03.028
    Journal articles | 2018
    Professor Diane Fatkin
    Minoche AE; Horvat C; Johnson R; Gayevskiy V; Morton SU; Drew AP; Woo K; Statham AL; Lundie B; Bagnall RD; Ingles J; Semsarian C; Seidman JG; Seidman CE; Dinger ME; Cowley MJ; Fatkin D, 2018, 'Response to Brodehl et al.', Genetics in Medicine, pp. 1 - 2, http://dx.doi.org/10.1038/s41436-018-0292-1
    Journal articles | 2018
    Professor Diane Fatkin
    Roselli C; Chaffin MD; Weng LC; Aeschbacher S; Ahlberg G; Albert CM; Almgren P; Alonso A; Anderson CD; Aragam KG; Arking DE; Barnard J; Bartz TM; Benjamin EJ; Bihlmeyer NA; Bis JC; Bloom HL; Boerwinkle E; Bottinger EB; Brody JA; Calkins H; Campbell A; Cappola TP; Carlquist J; Chasman DI; Chen LY; Chen YDI; Choi EK; Choi SH; Christophersen IE; Chung MK; Cole JW; Conen D; Cook J; Crijns HJ; Cutler MJ; Damrauer SM; Daniels BR; Darbar D; Delgado G; Denny JC; Dichgans M; Dörr M; Dudink EA; Dudley SC; Esa N; Esko T; Eskola M; Fatkin D; Felix SB; Ford I; Franco OH; Geelhoed B; Grewal RP; Gudnason V; Guo X; Gupta N; Gustafsson S; Gutmann R; Hamsten A; Harris TB; Hayward C; Heckbert SR; Hernesniemi J; Hocking LJ; Hofman A; Horimoto ARVR; Huang J; Huang PL; Huffman J; Ingelsson E; Ipek EG; Ito K; Jimenez-Conde J; Johnson R; Jukema JW; Kääb S; Kähönen M; Kamatani Y; Kane JP; Kastrati A; Kathiresan S; Katschnig-Winter P; Kavousi M; Kessler T; Kietselaer BL; Kirchhof P; Kleber ME; Knight S; Krieger JE; Kubo M; Launer LJ; Laurikka J; Lehtimäki T; Leineweber K; Lemaitre RN; Li M; Lim HE; Lin HJ; Lin H, 2018, 'Multi-ethnic genome-wide association study for atrial fibrillation', Nature Genetics, vol. 50, pp. 1225 - 1233, http://dx.doi.org/10.1038/s41588-018-0133-9
    Journal articles | 2018
    Professor Diane Fatkin
    Huttner IG; Wang LW; Santiago CF; Horvat C; Johnson R; Cheng D; von Frieling-Salewsky M; Hillcoat K; Bemand TJ; Trivedi G; Braet F; Hesselson D; Alford K; Hayward CS; Seidman JG; Seidman CE; Feneley MP; Linke WA; Fatkin D, 2018, 'A-Band Titin Truncation in Zebrafish Causes Dilated Cardiomyopathy and Hemodynamic Stress Intolerance', Circulation. Genomic and precision medicine, vol. 11, pp. e002135, http://dx.doi.org/10.1161/CIRCGEN.118.002135
    Journal articles | 2018
    Professor Diane Fatkin
    Zhang H; Dvornikov AV; Huttner IG; Ma X; Santiago CF; Fatkin D; Xu X, 2018, 'A Langendorff-like system to quantify cardiac pump function in adult zebrafish', DMM Disease Models and Mechanisms, vol. 11, http://dx.doi.org/10.1242/dmm.034819
    Journal articles | 2018
    Professor Diane Fatkin
    Bagnall RD; Ingles J; Dinger ME; Cowley MJ; Ross SB; Minoche AE; Lal S; Turner C; Colley A; Rajagopalan S; Berman Y; Ronan A; Fatkin D; Semsarian C, 2018, 'Whole Genome Sequencing Improves Outcomes of Genetic Testing in Patients With Hypertrophic Cardiomyopathy', Journal of the American College of Cardiology, vol. 72, pp. 419 - 429, http://dx.doi.org/10.1016/j.jacc.2018.04.078
    Journal articles | 2018
    Professor Diane Fatkin
    Wang LW; Kesteven SH; Huttner IG; Feneley MP; Fatkin D, 2018, 'High-frequency echocardiography ― transformative clinical and research applications in humans, mice, and zebrafish ―', Circulation Journal, vol. 82, pp. 620 - 628, http://dx.doi.org/10.1253/circj.CJ-18-0027
    Journal articles | 2018
    Professor Diane Fatkin
    Wang L; Huttner I; Santiago C; Hesselson D; Smith K; Linke W; Feneley M; Fatkin D, 2018, 'Titin Truncation Position Determines Propensity for Dilated Cardiomyopathy, Impaired Ventricular Relaxation and Passive Stiffness in Zebrafish', Heart, Lung and Circulation, vol. 27, pp. S42 - S43, http://dx.doi.org/10.1016/j.hlc.2018.06.004
    Journal articles | 2018
    Professor Diane Fatkin
    Fatkin D, 2018, 'Left ventricular diastolic dysfunction in hutchinson-gilford progeria syndrome', JAMA Cardiology, vol. 3, pp. 334 - 335, http://dx.doi.org/10.1001/jamacardio.2017.5377
    Journal articles | 2017
    Professor Diane Fatkin
    Nikolova-Krstevski V; Wagner S; Yu ZY; Cox CD; Cvetkovska J; Hill AP; Huttner IG; Benson V; Werdich AA; MacRae C; Feneley MP; Friedrich O; Martinac B; Fatkin D, 2017, 'Endocardial TRPC-6 Channels Act as Atrial Mechanosensors and Load-Dependent Modulators of Endocardial/Myocardial Cross-Talk', JACC: Basic to Translational Science, vol. 2, pp. 575 - 590, http://dx.doi.org/10.1016/j.jacbts.2017.05.006
    Journal articles | 2017
    Professor Diane Fatkin
    Friedrich O; Schneidereit D; Nikolaev YA; Nikolova-Krstevski V; Schürmann S; Wirth-Hücking A; Merten AL; Fatkin D; Martinac B, 2017, 'Adding dimension to cellular mechanotransduction: Advances in biomedical engineering of multiaxial cell-stretch systems and their application to cardiovascular biomechanics and mechano-signaling', Progress in Biophysics and Molecular Biology, vol. 130, pp. 170 - 191, http://dx.doi.org/10.1016/j.pbiomolbio.2017.06.011
    Journal articles | 2017
    Professor Diane Fatkin
    Fatkin D; Johnson R; McGaughran J; Weintraub RG; Atherton JJ, 2017, 'Position Statement on the Diagnosis and Management of Familial Dilated Cardiomyopathy', Heart Lung and Circulation, vol. 26, pp. 1127 - 1132, http://dx.doi.org/10.1016/j.hlc.2017.04.021
    Journal articles | 2017
    Professor Diane Fatkin
    Fatkin D; Huttner IG; Martin I, 2017, 'Titin-truncating mutations in dilated cardiomyopathy: the long and short of it', Current Opinion in Cardiology, vol. 32, pp. 232 - 238, http://dx.doi.org/10.1097/HCO.0000000000000382
    Journal articles | 2017
    Professor Diane Fatkin
    Fatkin D; Johnson R, 2017, 'Are Double Mutations Double Trouble?', Circulation: Cardiovascular Genetics, vol. 10, http://dx.doi.org/10.1161/CIRCGENETICS.117.001749
    Journal articles | 2017
    Professor Diane Fatkin
    Huttner I; Wang L; Santiago C; Horvat C; Johnson R; Cheng D; Braet F; Hesselson D; Feneley M; Fatkin D, 2017, 'A Zebrafish Model of a Human Titin-truncating Mutation Exhibits Spontaneous, Age-dependent and Load-exacerbated Dilated Cardiomyopathy', Heart, Lung and Circulation, vol. 26, pp. S43 - S43, http://dx.doi.org/10.1016/j.hlc.2017.06.002
    Journal articles | 2017
    Professor Diane Fatkin
    Furtado MB; Wilmanns JC; Chandran A; Perera J; Hon O; Biben C; Willow TJ; Nim HT; Kaur G; Simonds S; Wu Q; Willians D; Salimova E; Plachta N; Denegre JM; Murray SA; Fatkin D; Cowley M; Pearson JT; Kaye D; Ramialison M; Harvey RP; Rosenthal NA; Costa MW, 2017, 'Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling', JCI insight, vol. 2, pp. e88271, http://dx.doi.org/10.1172/jci.insight.88271
    Journal articles | 2017
    Professor Diane Fatkin
    Fatkin D; Santiago CF; Huttner IG; Lubitz SA; Ellinor PT, 2017, 'Genetics of Atrial Fibrillation: State of the Art in 2017', Heart Lung and Circulation, vol. 26, pp. 894 - 901, http://dx.doi.org/10.1016/j.hlc.2017.04.008
    Journal articles | 2017
    Professor Diane Fatkin
    Ito K; Patel PN; Gorham JM; McDonough B; DePalma SR; Adler EE; Lam L; MacRae CA; Mohiuddin SM; Fatkin D; Seidman CE; Seidman JG, 2017, 'Identification of pathogenic gene mutations in LMNA and MYBPC3 that alter RNA splicing', Proceedings of the National Academy of Sciences of the United States of America, vol. 114, pp. 7689 - 7694, http://dx.doi.org/10.1073/pnas.1707741114
    Journal articles | 2017
    Professor Diane Fatkin
    Wang LW; Huttner IG; Santiago CF; Kesteven SH; Yu ZY; Feneley MP; Fatkin D; Martin I, 2017, 'Standardized echocardiographic assessment of cardiac function in normal adult zebrafish and heart disease models', DMM Disease Models and Mechanisms, vol. 10, pp. 63 - 76, http://dx.doi.org/10.1242/dmm.026989
    Journal articles | 2017
    Professor Diane Fatkin
    Singh L; Fatkin D; Duque G, 2017, 'Lamin A(+/-) mice as a new animal model to study osteosarcopenia', AUSTRALASIAN JOURNAL ON AGEING, vol. 36, pp. 25 - 26, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000397496400033&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2016
    Professor Diane Fatkin
    Iyngkaran P; Thomas MC; Johnson R; French J; Ilton M; McDonald P; Hare DL; Fatkin D, 2016, 'Contextualizing genetics for regional heart failure care', Current Cardiology Reviews, vol. 12, pp. 231 - 242, http://dx.doi.org/10.2174/1573403X12666160606123103
    Journal articles | 2016
    Professor Diane Fatkin
    Fatkin D; Lam L; Herman DS; Benson CC; Felkin LE; Barton PJ; Walsh R; Candan S; Ware JS; Roberts AM; Chung WK; Smoot L; Bornaun H; keogh A; Macdonald P; Hayward CS; Seidman JG; Roberts AE; Cook SA; Seidman CE, 2016, 'Titin truncating mutations: a rare cause of dilated cardiomyopathy in the young', Progress in Pediatric Cardiology, vol. 40, pp. 41 - 45, http://dx.doi.org/10.1016/j.ppedcard.2016.01.003
    Journal articles | 2016
    Professor Diane Fatkin
    Christensen AH; Chatelain FC; Huttner IG; Olesen MS; Soka M; Feliciangeli S; Horvat C; Santiago CF; Vandenberg JI; Schmitt N; Olesen SP; Lesage F; Fatkin D; Martin I, 2016, 'The two-pore domain potassium channel, TWIK-1, has a role in the regulation of heart rate and atrial size', Journal of Molecular and Cellular Cardiology, vol. 97, pp. 24 - 35, http://dx.doi.org/10.1016/j.yjmcc.2016.04.006
    Journal articles | 2016
    Professor Diane Fatkin
    Wang L; Huttner I; Santiago C; Yu Z; Kesteven S; Feneley M; Fatkin D, 2016, 'Development and Validation of a Novel Technique for High Frequency Echocardiography in Zebrafish Models of Health and Disease Provide Key Insights into Cardiac Physiology and Applications for Studying Heart Failure', Heart, Lung and Circulation, vol. 25, pp. S106 - S106, http://dx.doi.org/10.1016/j.hlc.2016.06.251
    Journal articles | 2015
    Professor Diane Fatkin
    Cannon L; Yu ZY; Marciniec T; Waardenberg AJ; Iismaa SE; Nikolova-Krstevski V; Neist E; Ohanian M; Qiu MR; Rainer S; Harvey RP; Feneley MP; Graham RM; Fatkin D, 2015, 'Irreversible triggers for hypertrophic cardiomyopathy are established in the early postnatal period', Journal of the American College of Cardiology, vol. 65, pp. 560 - 569, http://dx.doi.org/10.1016/j.jacc.2014.10.069
    Journal articles | 2015
    Professor Diane Fatkin
    Roberts AM; Ware JS; Herman DS; Schafer S; Baksi J; Bick AG; Buchan RJ; Walsh R; John S; Wilkinson S; Mazzarotto F; Felkin LE; Gong S; Macarthur JAL; Cunningham F; Flannick J; Gabriel SB; Altshuler DM; MacDonald PS; Heinig M; Keogh AM; Hayward CS; Banner NR; Pennell DJ; O'Regan DP; San TR; De Marvao A; Dawes TJW; Gulati A; Birks EJ; Yacoub MH; Radke M; Gotthardt M; Wilson JG; O'Donnell CJ; Prasad SK; Barton PJR; Fatkin D; Hubner N; Seidman JG; Seidman CE; Cook SA, 2015, 'Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease', Science Translational Medicine, vol. 7, http://dx.doi.org/10.1126/scitranslmed.3010134
    Journal articles | 2015
    Professor Diane Fatkin
    Wang LW; Grygiel JJ; O'Neill JH; Fatkin D; Feneley MP, 2015, 'Snowflakes in the heart: an ultrasonic marker of severe hypercoagulability', The Lancet, vol. 385, pp. 302 - 302, http://dx.doi.org/10.1016/S0140-6736(14)62221-2
    Journal articles | 2015
    Professor Diane Fatkin
    Nikolova-Krstevski V; Wagner S; Cvetkovska J; Martinac B; Friedrich O; Fatkin D, 2015, 'TRPC6 (transient receptor potential Ca2+ channel 6) activity in the atrial endocardium exposed to increased mechanical stress is determined by the duration of the mechanical stretch stimuli', Heart, Lung and Circulation, vol. 24, pp. S183 - S183, http://dx.doi.org/10.1016/j.hlc.2015.06.169
    Journal articles | 2015
    Professor Diane Fatkin
    Wang L; Kesteven S; Imtiaz M; Martin I; Feneley M; Fatkin D, 2015, 'Navigating uncharted waters: novel echocardiography techniques for non-invasive in-vivo assessment of contractile function in adult zebrafish and its potential applications for research in cardiovascular genetics', Heart, Lung and Circulation, vol. 24, pp. S403 - S403, http://dx.doi.org/10.1016/j.hlc.2015.06.676
    Journal articles | 2014
    Professor Diane Fatkin
    Johnson R; Stockhammer K; Soka M; Ohanian M; Lam L; Fatkin D, 2014, 'Truncating Titin mutations: Are they a primary cause of dilated cardiomyopathy or a susceptibility factor?', Heart Lung Circ, vol. 23 Suppl 2, pp. e11 - e12, http://dx.doi.org/10.1016/j.hlc.2014.07.030
    Journal articles | 2014
    Professor Diane Fatkin
    Fatkin D; Seidman CE; Seidman JG, 2014, 'Genetics and disease of ventricular muscle.', Cold Spring Harbor perspectives in medicine, vol. 4, http://dx.doi.org/10.1101/cshperspect.a021063
    Journal articles | 2014
    Professor Diane Fatkin
    Yu ZY; Tan JC; McMahon AC; Iismaa SE; Xiao H; Kesteven SH; Reichelt ME; Mohl MC; Smith NJ; Fatkin D; Allen D; Head SI; Graham RM; Feneley MP, 2014, 'RhoA/ROCK signaling and pleiotropic α1A-adrenergic receptor regulation of cardiac contractility', PLoS ONE, vol. 9, http://dx.doi.org/10.1371/journal.pone.0099024
    Journal articles | 2014
    Professor Diane Fatkin
    Ballouz S; Liu JY; Oti M; Gaeta B; Fatkin D; Bahlo M; Wouters MA, 2014, 'Candidate disease gene prediction using : application to a genome-wide association study on coronary artery disease', Molecular Genetics & Genomic Medicine, vol. 2, pp. 44 - 57, http://dx.doi.org/10.1002/mgg3.40
    Journal articles | 2014
    Professor Diane Fatkin
    Martin I; Jacoby A; Smith K; Berger J; Trivedi G; Fatkin D, 2014, 'PT350 A novel zebrafish model of dilated cardiomyopathy', Global Heart, vol. 9, pp. e235 - e235, http://dx.doi.org/10.1016/j.gheart.2014.03.2074
    Journal articles | 2014
    Professor Diane Fatkin
    Nikolova-Krstevski V; Nikolova-Krstevski V; Jacoby A; Martin I; Trivedi G; Dobrzynski H; Fatkin D, 2014, 'Novel role for the large conductance Ca2+-activated K+ channel (BKCa) as a determinant of cardiac function', Global Heart, vol. 9, pp. e5, http://dx.doi.org/10.1016/j.gheart.2014.03.1238
    Journal articles | 2014
    Professor Diane Fatkin
    Martin I; Jacoby A; Smith K; Berger J; Trivedi G; Fatkin D, 2014, 'Identifying the genetic cause of DCM in a zebrafish mutant.', Heart Lung Circ, vol. 23 Suppl 2, pp. e2, http://dx.doi.org/10.1016/j.hlc.2014.07.004
    Journal articles | 2014
    Professor Diane Fatkin
    Martin I; Christensen A; Soka M; Fatkin D, 2014, 'In-vivo characterisation and mutation screening of the cardiac two-pore potassium channel, TWIK-1.', Heart Lung Circ, vol. 23 Suppl 2, pp. e14, http://dx.doi.org/10.1016/j.hlc.2014.07.036
    Journal articles | 2013
    Professor Diane Fatkin
    Christensen AH; Fatkin D, 2013, 'Efficacy of carvedilol in pediatric heart failure', Future Cardiology, vol. 9, pp. 475 - 478, http://dx.doi.org/10.2217/fca.13.36
    Journal articles | 2013
    Professor Diane Fatkin
    Huttner IG; Trivedi G; Jacoby A; Mann SA; Vandenberg JI; Fatkin D, 2013, 'A transgenic zebrafish model of a human cardiac sodium channel mutation exhibits bradycardia, conduction-system abnormalities and early death', Journal of Molecular and Cellular Cardiology, vol. 61, pp. 123 - 132, http://dx.doi.org/10.1016/j.yjmcc.2013.06.005
    Journal articles | 2013
    Professor Diane Fatkin
    Priori SG; Wilde AA; Horie M; Cho Y; Behr ER; Berul C; Blom N; Brugada J; Chiang CE; Huikuri H; Kannankeril P; Krahn A; Leenhardt A; Moss A; Schwartz PJ; Shimizu W; Tomaselli G; Tracy C; Document Reviewers ; Ackerman M; Belhassen B; Estes NAM; Fatkin D; Kalman J; Kaufman E; Kirchhof P; Schulze-Bahr E; Wolpert C; Vohra J; Refaat M; Etheridge SP; Campbell RM; Martin ET; Quek SC; Heart Rhythm Society ; European Heart Rhythm Association ; Asia Pacific Heart Rhythm Society , 2013, 'Executive summary: HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes.', Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, vol. 15, pp. 1389 - 1406, http://dx.doi.org/10.1093/europace/eut272
    Journal articles | 2013
    Professor Diane Fatkin
    Costa MW; Guo G; Wolstein O; Vale M; Castro ML; Wang L; Otway R; Riek P; Cochrane N; Furtado M; Semsarian C; Weintraub RG; Yeoh T; Hayward C; Keogh A; Macdonald P; Feneley M; Graham RM; Seidman JG; Seidman CE; Rosenthal N; Fatkin D; Harvey RP, 2013, 'Functional Characterization of a Novel Mutation in NKX2-5 Associated With Congenital Heart Disease and Adult-Onset Cardiomyopathy', Circulation: Cardiovascular Genetics, vol. 6, pp. 238 - 247, http://dx.doi.org/10.1161/CIRCGENETICS.113.000057
    Journal articles | 2013
    Professor Diane Fatkin
    Liang B; Soka M; Christensen AH; Olesen MS; Larsen AP; Knop FK; Wang F; Nielsen JB; Andersen MN; Humphreys D; Mann SA; Huttner IG; Vandenberg JI; Svendsen JH; Haunsø S; Preiss T; Seebohm G; Olesen SP; Schmitt N; Fatkin D, 2013, 'Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis.', J Mol Cell Cardiol, vol. 67, pp. 69 - 76, http://dx.doi.org/10.1016/j.yjmcc.2013.12.014
    Journal articles | 2013
    Professor Diane Fatkin
    Ohanian M; Humphreys DT; Anderson E; Preiss T; Fatkin D, 2013, 'A heterozygous variant in the human cardiac miR-133 gene, MIR133A2, alters miRNA duplex processing and strand abundance.', BMC genetics, vol. 14, http://dx.doi.org/10.1186/1471-2156-14-18
    Journal articles | 2013
    Professor Diane Fatkin
    Nikolova-Krstevski V; Wagner S; Friedrich O; Fatkin D, 2013, 'Abstract 044: Transient Receptor Potential Channel 6 (TRPC6) Is An Important Mediator Of Mechanical Stretch Responses In The Atrial Endocardial Endothelium.', Circulation Research, vol. 113, http://dx.doi.org/10.1161/res.113.suppl_1.a044
    Journal articles | 2013
    Professor Diane Fatkin
    Ballouz S; Liu JY; George RA; Bains N; Liu A; Oti M; Gaeta B; Fatkin D; Wouters MA, 2013, 'Gentrepid V2.0: A web server for candidate disease gene prediction', BMC Bioinformatics, vol. 14, http://dx.doi.org/10.1186/1471-2105-14-249
    Journal articles | 2013
    Professor Diane Fatkin
    Olesen M; Liang B; Soka M; Larsen AP; Knop FK; Wang F; Nielsen JB; Andersen MN; Humphreys D; Mann SA; Vandenberg JI; Svendsen JH; Haunso S; Preiss T; Seebohm G; Olesen S-P; Schmitt N; Fatkin D, 2013, 'TASK-1 potassium channel mutations in atrial fibrillation', European Heart Journal, vol. 34, pp. 3411 - 3411, http://dx.doi.org/10.1093/eurheartj/eht309.3411
    Journal articles | 2013
    Professor Diane Fatkin
    Nikolova-Krstevski V; Wagner S; Bowman I; Friedrich O; Fatkin D, 2013, 'TRPC6 (Canonical Transient Receptor Potential Ca2+ Channel 6) is An Important Mediator of Mechanical Stretch Responses in the Atrial Endocardial Endothelium', Heart, Lung and Circulation, vol. 22, pp. S5 - S6, http://dx.doi.org/10.1016/j.hlc.2013.05.011
    Journal articles | 2013
    Professor Diane Fatkin
    Martin I; Trivedi G; Jacoby A; Mann S; Vandenberg J; Fatkin D, 2013, 'A Transgenic Zebrafish Model of a Human Cardiac Sodium Channel Mutation Exhibits Bradycardia, Conduction-System Abnormalities and Early Death', Heart, Lung and Circulation, vol. 22, pp. S227 - S227, http://dx.doi.org/10.1016/j.hlc.2013.05.539
    Journal articles | 2013
    Professor Diane Fatkin
    Fatkin D; Nikolova-Krstevski V, 2013, 'Atrial Cardiomyopathy An Orphan Disease or Common Disorder?', Circulation: Cardiovascular Genetics, vol. 6, pp. 5 - 6, http://dx.doi.org/10.1161/CIRCGENETICS.111.000033
    Journal articles | 2013
    Professor Diane Fatkin
    Yu Z; Tan J; McMahon A; Iismaa S; Xiao X; Kesteven S; Reichelt M; Mohl M; Dai Y; Sketchley A; Yang L; Gong H; Fatkin D; Allen D; Head S; Graham R; Feneley M, 2013, 'Studies of a Mouse Model of Cardiac α1A-Adrenergic Receptor Overexpression Provide Evidence For a Critical Role of RhoA/ROCK Signalling in Cardiac Contractility', Heart, Lung and Circulation, vol. 22, pp. S59 - S59, http://dx.doi.org/10.1016/j.hlc.2013.05.143
    Journal articles | 2012
    Professor Diane Fatkin
    Vidal C; Bermeo S; Fatkin D; Duque G, 2012, 'Role of the nuclear envelope in the pathogenesis of age-related bone loss and osteoporosis.', Bonekey Rep, vol. 1, pp. 62, http://dx.doi.org/10.1038/bonekey.2012.62
    Journal articles | 2012
    Professor Diane Fatkin
    Zhang BT; Whitehead NP; Gervasio OL; Reardon TF; Vale M; Fatkin D; Dietrich A; Yeung EW; Allen DG, 2012, 'Pathways of Ca2+ entry and cytoskeletal damage following eccentric contractions in mouse skeletal muscle', Journal of Applied Physiology, vol. 112, pp. 2077 - 2086, http://dx.doi.org/10.1152/japplphysiol.00770.2011
    Journal articles | 2012
    Professor Diane Fatkin
    Ohanian M; Otway R; Fatkin D, 2012, 'Heuristic methods for finding pathogenic variants in gene coding sequences.', Journal of the American Heart Association, vol. 1, http://dx.doi.org/10.1161/JAHA.112.002642
    Journal articles | 2012
    Professor Diane Fatkin
    Vandenberg JI; Mann SA; Castro ML; Ohanian M; Guo G; Zodgekar PR; Sheu A; Stockhammer K; Fatkin D; Subbiah RN, 2012, 'R222Q SCN5A Mutation Is Associated With Reversible Ventricular Ectopy and Dilated Cardiomyopathy', Journal of the American College of Cardiology, vol. 60, pp. 1566 - 1573, http://dx.doi.org/10.1016/j.jacc.2012.05.050
    Journal articles | 2012
    Professor Diane Fatkin
    Humphreys DT; Hynes CJ; Patel HR; Wei G; Cannon LE; Fatkin D; Suter CM; Clancy JL; Preiss T, 2012, 'Complexity of murine cardiomyocyte miRNA biogenesis, sequence variant expression and function', PLoS One, vol. 7, pp. e30933, http://dx.doi.org/10.1371/journal.pone.0030933
    Journal articles | 2012
    Professor Diane Fatkin
    Fatkin D, 2012, 'Familial dilated cardiomyopathy: Current challenges and future directions', Global Cardiology Science and Practice, vol. 2012, pp. 8 - 8, http://dx.doi.org/10.5339/gcsp.2012.8
    Journal articles | 2012
    Professor Diane Fatkin
    Nikolova-Krstevski V; Leimena C; Fatkin D, 2012, 'Mechanical Stretch Alters the Morphology and Function of Atrial Endocardial Endothelial Cells', Heart, Lung and Circulation, vol. 21, pp. S61 - S61, http://dx.doi.org/10.1016/j.hlc.2012.05.157
    Journal articles | 2012
    Professor Diane Fatkin
    Ingles J; Zodgekar PR; Yeates L; Macciocca I; McGaughran J; Semsarian C; Fatkin D, 2012, 'Erratum to "Guidelines for Genetic Testing of Inherited Cardiac Disorders" [Heart Lung Circ. 20 (2011) 681-687]', Heart Lung and Circulation, vol. 21, pp. 57, http://dx.doi.org/10.1016/j.hlc.2011.10.007
    Journal articles | 2011
    Professor Diane Fatkin
    Ingles J; Zodgekar PR; Yeates L; Macciocca I; Semsarian C; Fatkin D, 2011, 'Guidelines for Genetic Testing of Inherited Cardiac Disorders', Heart Lung and Circulation, vol. 20, pp. 681 - 687, http://dx.doi.org/10.1016/j.hlc.2011.07.013
    Journal articles | 2011
    Professor Diane Fatkin
    Fatkin D, 2011, 'Guidelines for the Diagnosis and Management of Familial Dilated Cardiomyopathy', Heart Lung and Circulation, vol. 20, pp. 691 - 693, http://dx.doi.org/10.1016/j.hlc.2011.07.008
    Journal articles | 2011
    Professor Diane Fatkin
    Fatkin D; li W; Yeo L; Vidal C; McCorquodale T; Herrmann M; Duque G, 2011, 'Decreased bone formation and osteopenia in lamin a/c-deficient mice', PLoS One, vol. 6, pp. e19313, http://dx.doi.org/10.1371/journal.pone.0019313
    Journal articles | 2011
    Professor Diane Fatkin
    Duque G; Li W; Yeo LS; Vidal C; Fatkin D, 2011, 'Attenuated anabolic response to exercise in lamin A/C haploinsufficient mice', Bone, vol. 49, pp. 412 - 418, http://dx.doi.org/10.1016/j.bone.2011.04.023
    Journal articles | 2011
    Professor Diane Fatkin
    Fatkin D; Mohl M; Iismaa SE; Xiao XH; Friedrich O; Wagner ; Nikolova-Krstevski ; Wu J; Yu ZY; Feneley MP; Allen ; Graham RM, 2011, 'Regulation of murine cardiac contractility by activation of alpha(1A)-adrenergic receptor-operated Ca(2+) entry', Cardiovascular Research, vol. 91, pp. 310 - 319, http://dx.doi.org/10.1093/cvr/cvr081
    Journal articles | 2011
    Professor Diane Fatkin
    Fatkin D; Yeoh TB; Hayward CS; Benson V; Sheu A; Richmond Z; Feneley MP; Keogh AM; Macdonald PS, 2011, 'A Randomised, Placebo-controlled Trial of Carvedilol in Early Familial Dilated Cardiomyopathy', Heart Lung and Circulation, vol. 20, pp. 566 - 573, http://dx.doi.org/10.1016/j.hlc.2011.06.004
    Journal articles | 2011
    Professor Diane Fatkin
    Floro KL; Artap S; Preis JI; Fatkin D; Chapman G; Furtado MB; Harvey RP; Hamada H; Sparrow DB; Dunwoodie SL, 2011, 'Loss of Cited2 causes congenital heart disease by perturbing left-right patterning of the body axis', Human Molecular Genetics, vol. 20, pp. 1097 - 1110, http://dx.doi.org/10.1093/hmg/ddq554
    Journal articles | 2011
    Professor Diane Fatkin
    Tong J; Vidal C; Yeo LS; Fatkin D; Duque G, 2011, 'Lamin A/C deficiency is associated with fat infiltration of muscle and bone', Mechanisms of Ageing and Development, vol. 132, pp. 552 - 559, http://dx.doi.org/10.1016/j.mad.2011.09.004
    Journal articles | 2011
    Professor Diane Fatkin
    Fatkin D; Yeoh TB; Hayward CS; Benson V; Sheu A; Richmond Z; Feneley MP; Keogh AM; Macdonald PS, 2011, 'Evaluation of left ventricular enlargement as a marker of early disease in familial dilated cardiomyopathy', Circulation: Cardiovascular Genetics, vol. 4, pp. 342 - 348, http://dx.doi.org/10.1161/CIRCGENETICS.110.958918
    Journal articles | 2011
    Professor Diane Fatkin
    Harvey RP; Dunwoodie SL; Fatkin D; Qian L; Wythe JD; Liu J; Liu J; Vogler G; Mohapatra B; Otway R; Huang Y; King IN; Maillet M; Zheng Y; Crawley T; Taghli-Lamallem O; Semsarian C; Winlaw D, 2011, 'Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species', Journal of Cell Biology, vol. 193, pp. 1181 - 1196, http://dx.doi.org/10.1083/jcb.201006114
    Journal articles | 2011
    Professor Diane Fatkin
    Nikolova V; Leimena C; Xiao X; Kesteven SH; Tan J; Yeo LS; Yu ZY; Zhang Q; Carlton A; Head SI; Shanahan C; Feneley MP; Fatkin D, 2011, 'Nesprin-1 and actin contribute to nuclear and cytoskeletal defects in lamin A/C-deficient cardiomyopathy', Journal of Molecular and Cellular Cardiology, vol. 50, pp. 479 - 486, http://dx.doi.org/10.1016/j.yjmcc.2010.12.001
    Journal articles | 2011
    Professor Diane Fatkin
    Moradi marjaneh M; Kirk EP; Posch MG; Ozcelik C; Berger F; Hetzer R; Otway R; Butler TL; Blue GM; Griffiths L; Fatkin D; Martinson JJ; Winlaw D; Feneley MP; Harvey RP, 2011, 'Investigation of Association between PFO Complicated by Cryptogenic Stroke and a Common Variant of the Cardiac Transcription Factor GATA4', PLoS One, vol. 6, pp. e20711, http://dx.doi.org/10.1371/journal.pone.0020711
    Journal articles | 2011
    Professor Diane Fatkin
    Cannon L; Marciniec T; Mearns B; Vale M; Nikolova-Krstevski V; Kesteven S; Raynor S; Feneley M; Graham R; Fatkin D, 2011, 'A Regulatable Model of Mutant α-Myosin Heavy Chain Overexpression to Study the Structural and Functional Consequences of Hypertrophy Regression', Heart, Lung and Circulation, vol. 20, pp. S1 - S1, http://dx.doi.org/10.1016/j.hlc.2011.05.004
    Journal articles | 2011
    Professor Diane Fatkin
    Qian L; Wythe JD; Liu J; Cartry J; Vogler G; Mohapatra B; Otway RT; Huang Y; King IN; Maillet M; Zheng Y; Crawley T; Taghli-Lamallem O; Semsarian C; Dunwoodie S; Winlaw D; Harvey RP; Fatkin D; Towbin JA; Molkentin JD; Srivastava D; Ocorr K; Bruneau BG; Bodmer R, 2011, 'Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species', The Journal of Experimental Medicine, vol. 208, pp. i20 - i20, http://dx.doi.org/10.1084/jem2087oia20
    Journal articles | 2010
    Professor Diane Fatkin
    Chandar S; Yeo LS; Leimena C; Tan J; Xiao X; Nikolova V; Yasuoka Y; Gardiner-Garden M; Wu J; Kesteven SH; Karlsdotter ; Natarajan S; Carlton A; Rainer SP; Feneley MP; Fatkin D, 2010, 'Effects of mechanical stress and carvedilol in lamin A/C-deficient dilated cardiomyopathy', Circulation Research, vol. 106, pp. 573 - 582, http://dx.doi.org/10.1161/CIRCRESAHA.109.204388
    Journal articles | 2010
    Professor Diane Fatkin
    Granados-riveron J; Ghosh TK; Pope M; Bu''Lock F; Thornborough C; Eason J; Kirk EP; Fatkin D; Feneley MP; Harvey RP; Armour J; Brook JD, 2010, 'Alpha-Cardiac myosin heavy chain (MYH6) mutations affecting myofibril formation are associated with congenital heart defects', Human Molecular Genetics, vol. 19, pp. 4007 - 4016, http://dx.doi.org/10.1093/hmg/ddq315
    Journal articles | 2010
    Professor Diane Fatkin
    Fatkin D; Otway ; Richmond Z, 2010, 'Genetics of dilated cardiomyopathy', Heart Failure Clinics, vol. 6, pp. 129 - 140, http://dx.doi.org/10.1016/j.hfc.2009.11.003
    Journal articles | 2009
    Professor Diane Fatkin
    Carballo S; Robinson P; Otway R; Fatkin D; Jongbloed J; De Jonge N; Blair E; Van Tintelen J; Redwood C; Watkins H, 2009, 'Identification and functional characterization of cardiac troponin 1 as a novel disease gene in autosomal dominant dilated cardiomyopathy', Circulation Research, vol. 105, pp. 375 - 382, http://dx.doi.org/10.1161/CIRCRESAHA.109.196055
    Journal articles | 2009
    Professor Diane Fatkin
    Teber ET; Liu JY; Ballouz S; Fatkin D; Wouters MA, 2009, 'Comparison of automated candidate gene prediction systems using genes implicated in type 2 diabetes by genome-wide association studies', BMC bioinformatics, vol. 10, pp. 1 - 10, http://dx.doi.org/10.1186/1471-2105-10-S1-S69
    Journal articles | 2009
    Professor Diane Fatkin
    Yeoh T; Hayward CS; Benson V; Macdonald PS; Feneley MP; Keogh A; Fatkin D, 2009, 'Carvedilol-Treatment in Asymptomatic Early Familial Dilated Cardiomyopathy: A Randomised Double-Blind Placebo Controlled Trial', Heart, Lung and Circulation, vol. 18, pp. S172 - S172, http://dx.doi.org/10.1016/j.hlc.2009.05.390
    Journal articles | 2009
    Professor Diane Fatkin
    Yeoh T; Hayward CS; Benson V; Macdonald PS; Feneley MP; Keogh A; Fatkin D, 2009, 'Echocardiographic Assessment of Asymptomatic Early Dilated Cardiomyopathy', Heart, Lung and Circulation, vol. 18, pp. S175 - S175, http://dx.doi.org/10.1016/j.hlc.2009.05.397
    Journal articles | 2009
    Professor Diane Fatkin
    Hayward CS; Yeoh T; Benson VL; Keogh AM; Macdonald PS; Feneley MP; Fatkin D, 2009, 'Non-invasive Assessment of Preload Recruitable Stroke Work Relations in Preclinical Cardiomyopathy', Heart, Lung and Circulation, vol. 18, pp. S77 - S78, http://dx.doi.org/10.1016/j.hlc.2009.05.173
    Journal articles | 2009
    Professor Diane Fatkin
    Nikolova-Krstevski V; Leimena C; Carlton A; Stewart CL; Shanahan C; Fatkin D, 2009, 'Nesprin/actin cytoskeletal network is a critical determinant of cardiac function in lamin A/C deficient mice', Heart, Lung and Circulation, vol. 18, pp. S252 - S252, http://dx.doi.org/10.1016/j.hlc.2009.05.622
    Journal articles | 2008
    Professor Diane Fatkin
    Sparrow DB; Guillen-Navarro E; Fatkin D; Dunwoodie SL, 2008, 'Mutation of HAIRY-AND-ENHANCER-OF-SPLIT-7 in humans causes spondylocostal dysostosis', Human Molecular Genetics, vol. 17, pp. 3761 - 3766, http://dx.doi.org/10.1093/hmg/ddn272
    Journal articles | 2008
    Professor Diane Fatkin
    Palmer BM; Wang YT; Teekakirikul P; Hinson T; Fatkin D; Strouse S; VanBuren P; Seidman C; Maughan DW, 2008, 'Myofilament mechanical performance is enhanced by R403Q myosin in mouse myocardium independent of sex', American Journal of Physiology - Heart and Circulatory Physiology, vol. 294, pp. 1939 - 1947, http://dx.doi.org/10.1152/ajpheart.00644.2007
    Journal articles | 2008
    Professor Diane Fatkin
    Cannon L; Marciniec T; Mearns B; Graham RM; Fatkin D, 2008, 'Abstract 3435: Left Ventricular Hypertrophy is Resistant to Inhibition of Expression of the R403Q Alpha-Myosin Heavy Chain Cardiac Hypertrophy-Inducing Mutant Protein', Circulation, vol. 118, http://dx.doi.org/10.1161/circ.118.suppl_18.s_423-c
    Journal articles | 2007
    Professor Diane Fatkin
    Kirk EP; Sunde M; Costa M; Rankin S; Wolstein O; Castro ML; Butler T; Hyun C; Guo G; Otway R; Mackay J; Waddell L; Cole A; Hayward CS; Keogh AM; Macdonald PS; Griffiths L; Fatkin D; Sholler G; Zorn AM; Feneley MP; Winlaw D; Harvey RP; Butler , 2007, 'Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiornyopathy', American Journal of Human Genetics, vol. 81, pp. 280 - 291, http://dx.doi.org/10.1086/519530
    Journal articles | 2007
    Professor Diane Fatkin
    Fatkin D; Otway R; Vandenberg JI, 2007, 'Genes and atrial fibrillation - A new look at an old problem', Circulation, vol. 116, pp. 782 - 792, http://dx.doi.org/10.1161/CIRCULATIONAHA.106.688889
    Journal articles | 2007
    Professor Diane Fatkin
    Otway R; Vandenberg JI; Guo G; Varghese A; Castro ML; Liu JJ; Zhao J; Bursill JA; Wyse KR; Crotty H; Baddeley O; Walker BD; Kuchar D; Thorburn CW; Fatkin D, 2007, 'Stretch-sensitive KCNQ1 mutation - A link between genetic and environmental factors in the pathogenesis of atrial fibrillation?', Journal of the American College of Cardiology, vol. 49, pp. 578 - 586, http://dx.doi.org/10.1016/j.jacc.2006.09.044
    Journal articles | 2007
    Professor Diane Fatkin
    Fatkin D, 2007, 'Guidelines for the Diagnosis and Management of Familial Dilated Cardiomyopathy', Heart Lung and Circulation, vol. 16, pp. 19 - 21, http://dx.doi.org/10.1016/j.hlc.2006.10.018
    Journal articles | 2007
    Professor Diane Fatkin
    Otway R; Vandenberg JI; Fatkin D, 2007, 'Atrial Fibrillation-A New Cardiac Channelopathy', Heart Lung and Circulation, vol. 16, pp. 356 - 360, http://dx.doi.org/10.1016/j.hlc.2007.07.003
    Journal articles | 2007
    Professor Diane Fatkin
    Chandar S; Natarajan S; Michalicek J; Kesteven S; Wu J; Ahmed I; Fatkin D, 2007, 'Heart Rate Variability as a Prognostic Indicator in DCM Due to Lamin A/C Deficiency', Heart, Lung and Circulation, vol. 16, pp. S20 - S20, http://dx.doi.org/10.1016/j.hlc.2007.06.053
    Journal articles | 2006
    Professor Diane Fatkin
    Sparrow DB; Chapman G; Wouters MA; Whittock N; Ellard S; Fatkin D; Turnpenny PD; Kusumi K; Sillence D; Dunwoodie SL, 2006, 'Mutation of the LUNATIC FRINGE Gene in Humans Causes Spondylocostal Dysostosis with a Severe Vertebral Phenotype', American Journal of Human Genetics, vol. 78, pp. 25 - 34, http://dx.doi.org/10.1086/498879
    Journal articles | 2006
    Professor Diane Fatkin
    Liu JY; Feng LL; Bryson-Richardson RJ; Fatkin D; Wouters MA; George R, 2006, 'Analysis of protein sequence and interaction data for candidate disease gene prediction', Nucleic Acids Research, vol. 34, pp. 130 - 131, http://dx.doi.org/10.1093/nar/gkl707
    Journal articles | 2005
    Professor Diane Fatkin
    Stennard FA; Costa M; Lai D; Biden C; Furtado MB; Solloway MJ; McCulley D; Leimena C; Preis JI; Dunwoodie SL; Elliott D; Prall OW; Black B; Fatkin D; Harvey RJ, 2005, 'Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaption', Development (Cambridge), vol. 132, pp. 2451 - 2462, http://dx.doi.org/10.1242/dev.01799
    Journal articles | 2005
    Professor Diane Fatkin
    Collas P; Starr DA; Gruenbaum Y; Young SG; Shackleton S; Wilson KL; Bonne G; Davies K; Worman HJ; Goldman R; Goldman AE; Gerace L; Malone C; Shumaker DK; Shanahan CM; Fatkin D; Gasser SM; Hutchison C, 2005, 'Discussion', Novartis Foundation Symposium, vol. 264, pp. 219 - 226
    Journal articles | 2005
    Professor Diane Fatkin
    Young SG; Capeau J; Goldman A; Goldman RD; Wilson KL; Bonne G; Gruenbaum Y; Shackleton S; Burke B; Worman HJ; Fatkin D; Stewart CL, 2005, 'Discussion', Novartis Foundation Symposium, vol. 264, pp. 177 - 182
    Journal articles | 2005
    Professor Diane Fatkin
    Fatkin D; Bonne G; Davies K; Capeau J; Young SG; Wilson KL; Stewart CL; Giles WR; Goldman A; Goldman RD; Shackleton S; Gruenbaum Y; Julien JP; Worman HJ; Lévy N; Oshima J; Burke B; Gerace L; Lee RT, 2005, 'Discussion', Novartis Foundation Symposium, vol. 264, pp. 90 - 97
    Journal articles | 2005
    Professor Diane Fatkin
    Julien JP; Wilson KL; Gruenbaum Y; Goldman A; Goldman RD; Hutchison C; Gerace L; Young SG; Stewart CL; Capeau J; Morris GE; Gasser SM; Bonne G; Fatkin D; Burke B; Giles WR; Lee RT, 2005, 'Discussion', Novartis Foundation Symposium, vol. 264, pp. 273 - 278
    Journal articles | 2005
    Professor Diane Fatkin
    Goldman A; Goldman RD; Capeau J; Wilson KL; Young SG; Fatkin D; Julien JP; Davies K; Gasser SM; Burke B; Oshima J; Lévy N; Stewart CL, 2005, 'General discussion I', Novartis Foundation Symposium, vol. 264, pp. 227 - 230
    Journal articles | 2005
    Professor Diane Fatkin
    Collas P; Stewart CL; Gruenbaum Y; Oshima J; Young SG; Fatkin D; Capeau J; Julien JP; Lévy N; Goldman A; Goldman RD; Davies K; Wilson KL; Gasser SM; Courvalin JC; Bonne G, 2005, 'Discussion', Novartis Foundation Symposium, vol. 264, pp. 258 - 263
    Journal articles | 2005
    Professor Diane Fatkin
    Li J; Prall O; Heffernan C; Fatkin D; Feneley M; Graham R; Harvey R, 2005, 'Cardiomyocyte-lineage precursor cells in the adult heart', MECHANISMS OF DEVELOPMENT, vol. 122, pp. S136 - S136, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000207524100510&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2005
    Professor Diane Fatkin
    Fatkin D; Wilson KL; Gruenbaum Y; Ellis J; Julien JP; Shumaker D; Goldman A; Morris GE; Gerace L; Wilkins A, 2005, 'Discussion', Novartis Foundation Symposium, vol. 264, pp. 58 - 62
    Journal articles | 2005
    Professor Diane Fatkin
    Oshima J; Giles WR; Lee RT; Worman HJ; Hutchison C; Bonne G; Gerace L; Morris GE; Fatkin D; Goldman A; Goldman RD; Capeau J; Wilson KL; Shanahan CM; Julien JP; Stewart CL; Ellis J, 2005, 'Discussion', Novartis Foundation Symposium, vol. 264, pp. 133 - 139
    Journal articles | 2005
    Professor Diane Fatkin
    Wolstein O; Ahmed IM; Stennard FA; Fatkin D; Harvey RP, 2005, 'Role of cardiac transcription factor Tbx20 in adult heart function and disease', MECHANISMS OF DEVELOPMENT, vol. 122, pp. S60 - S60, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000207524100220&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2004
    Professor Diane Fatkin
    Nikolova V; Leimena C; McMahon A; Tan JC; Chandar S; Jogia DM; Kesteven SH; Michalicek J; Otway R; Verheyen et A, 2004, 'Defects in nuclear structure and function promote dilated cardiomyopathy in lamin A/C-deficient mice', Journal of Clinical Investigation, vol. 113, pp. 357 - 369, http://dx.doi.org/10.1172/JCI200419448
    Journal articles | 2004
    Professor Diane Fatkin
    Fatkin D; Nikolova V; Leimena C; McMahon A; Tan JC; Chandar S; Jogia DM; Kesteven S; Michalicek J; Otway R; Martin DI; Stewart C; Rainer SP; Feneley MP, 2004, 'Nuclear structure and function defects promote dilated cardiomyopathyin lamin A/C-deficient mice', Circulation, vol. 108, pp. 96 - 96, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000186360600510&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Journal articles | 2003
    Professor Diane Fatkin
    Elliott DA; Kirk EP; Yeoh T; Chandar S; McKenzie F; Taylor P; Grossfeld P; Fatkin D; Jones O; Hayes P; Feneley M; Harvey RP, 2003, 'Cardiac homeobox gene NKX2-5 mutations and congenital heart disease: Associations with atrial septal defect and hypoplastic left heart syndrome', Journal of the American College of Cardiology, vol. 41, pp. 2072 - 2076, http://dx.doi.org/10.1016/S0735-1097(03)00420-0
    Journal articles | 2003
    Professor Diane Fatkin
    Novotny J; Nikolova V; Fatkin D, 2003, 'Structural analysis of Imna gene mutations', Heart, Lung and Circulation, vol. 12, pp. A59 - A59, http://dx.doi.org/10.1046/j.1443-9506.2003.0240x.x
    Journal articles | 2003
    Professor Diane Fatkin
    Elliott DA; Kirk EP; Yeoh TB; Chandar S; McKenzie F; Taylor PC; Grossfeld P; Fatkin D; Jones OD; Hayes P; Feneley MP; Harvey RJ, 2003, 'Cardiac Homebox Gene NKX2-5 Mutations and Congenital Heart Disease', Journal of the American College of Cardiology, vol. 41, pp. 2072 - 2076
    Journal articles | 2002
    Professor Diane Fatkin
    Fatkin D; Graham RM, 2002, 'Molecular mechanisms of inherited cardiomyopathies', Physiological Reviews, vol. 82, pp. 945 - 980, http://dx.doi.org/10.1152/physrev.00012.2002
    Journal articles | 2001
    Professor Diane Fatkin
    McConnell BK; Fatkin D; Semsarian C; Jones KA; Georgakopoulos D; Maguire CT; Healey MJ; Mudd JO; Moskowitz IPG; Conner DA; Giewat M; Wakimoto H; Berul CI; Schoen FJ; Kass DA; Seidman CE; Seidman JG, 2001, 'Comparison of two murine models of familial hypertrophic cardiomyopathy', Circulation Research, vol. 88, pp. 383 - 389, http://dx.doi.org/10.1161/01.RES.88.4.383
    Journal articles | 2001
    Professor Diane Fatkin
    Bruneau BG; Bao ZZ; Fatkin D; Xavier-Neto J; Georgakopoulos D; Maguire CT; Berul CI; Kass DA; Kuroski-De Bold ML; De Bold AJ; Conner DA; Rosenthal N; Cepko CL; Seidman CE; Seidman JG, 2001, 'Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression', Molecular and Cellular Biology, vol. 21, pp. 1730 - 1736, http://dx.doi.org/10.1128/MCB.21.5.1730-1736.2001
    Journal articles | 2001
    Professor Diane Fatkin
    Semsarian C; Healey MJ; Fatkin D; Giewat M; Duffy C; Seidman CE; Seidman JG, 2001, 'A polymorphic modifier gene alters the hypertrophic response in a murine model of familial hypertrophic cardiomyopathy', Journal of Molecular and Cellular Cardiology, vol. 33, pp. 2055 - 2060, http://dx.doi.org/10.1006/jmcc.2001.1466
    Journal articles | 2001
    Professor Diane Fatkin
    Fatkin D; Graham RM; Spirito P; Maron BJ, 2001, 'Prognostic value of left ventricular hypertrophy in hypertrophic cardiomyopathy', New England Journal of Medicine, vol. 344, pp. 63 - 65, http://dx.doi.org/10.1056/NEJM200101043440115
    Journal articles | 2000
    Professor Diane Fatkin
    Fatkin D; McConnell BK; Mudd JO; Semsarian C; Moskowitz IGP; Schoen FJ; Giewat M; Seidman CE; Seidman JG, 2000, 'An abnormal Ca2+ response in mutant sarcomere protein-mediated familial hypertrophic cardiomyopathy', Journal of Clinical Investigation, vol. 106, pp. 1351 - 1359, http://dx.doi.org/10.1172/JCI11093
    Journal articles | 2000
    Professor Diane Fatkin
    Schönberger J; Levy H; Grünig E; Sangwatanaroj S; Fatkin D; MacRae C; Stäcker H; Halpin C; Eavey R; Philbin EF; Katus H; Seidman JG; Seidman CE, 2000, 'Dilated cardiomyopathy and sensorineural hearing loss: A heritable syndrome that maps to 6q23-24', Circulation, vol. 101, pp. 1812 - 1818, http://dx.doi.org/10.1161/01.CIR.101.15.1812
    Journal articles | 2000
    Professor Diane Fatkin
    Seidman JG; Semsarian C; McConnell BK; Fatkin D; Mudd J; Moskowitz I; Schoen F; Giewat M; Seidman C, 2000, 'Familial Hypertrophic Cardiomyopathy in Mice and Men', Biochemical Society Transactions, vol. 28, pp. A104 - A104, http://dx.doi.org/10.1042/bst028a104c
    Journal articles | 1999
    Professor Diane Fatkin
    Fatkin D; Christe ME; Aristizabal O; McConnell BK; Srinivasan S; Schoen FJ; Seidman CE; Turnbull DH; Seidman JG, 1999, 'Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the α cardiac myosin heavy chain gene', Journal of Clinical Investigation, vol. 103, pp. 147 - 153, http://dx.doi.org/10.1172/JCI4631
    Journal articles | 1999
    Professor Diane Fatkin
    Mehdirad AA; Fatkin D; DiMarco JP; MacRae CA; Wase A; Seidman JG; Seidman CE; Benson DW, 1999, 'Electrophysiologic characteristics of accessory atrioventricular connections in an inherited form of Wolff-Parkinson-White syndrome', Journal of Cardiovascular Electrophysiology, vol. 10, pp. 629 - 635, http://dx.doi.org/10.1111/j.1540-8167.1999.tb00239.x
    Journal articles | 1999
    Professor Diane Fatkin
    Fatkin D; Macrae C; Sasaki T; Wolff MR; Porcu M; Frenneaux M; Atherton J; Vidaillet HJ; Spudich S; De Girolami U; Seidman JG; Seidman CE; Muntoni F; Müehle G; Johnson W; McDonough B, 1999, 'Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease', New England Journal of Medicine, vol. 341, pp. 1715 - 1724, http://dx.doi.org/10.1056/NEJM199912023412302
    Journal articles | 1999
    Professor Diane Fatkin
    McConnell BK; Jones KA; Fatkin D; Arroyo LH; Lee RT; Aristizabal O; Turnbull DH; Georgakopoulos D; Kass D; Bond M; Niimura H; Schoen FJ; Conner D; Fischman DH; Seidman CE; Seidman JG, 1999, 'Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice', Journal of Clinical Investigation, vol. 104, pp. 1235 - 1244, http://dx.doi.org/10.1172/JCI7377
    Journal articles | 1999
    Professor Diane Fatkin
    Siu BL; Niimura H; Osborne JA; Fatkin D; MacRae C; Solomon S; Benson DW; Seidman JG; Seidman CE, 1999, 'Familial dilated cardiomyopathy locus maps to chromosome 2q31', Circulation, vol. 99, pp. 1022 - 1026, http://dx.doi.org/10.1161/01.CIR.99.8.1022
    Journal articles | 1999
    Professor Diane Fatkin
    Gruver EJ; Fatkin D; Dodds GA; Kisslo J; Maron BJ; Seidman JG; Seidman CE, 1999, 'Familial hypertrophic cardiomyopathy and atrial fibrillation caused by Arg663His beta-cardiac myosin heavy chain mutation', American Journal of Cardiology, vol. 83, pp. 13 - 18, http://dx.doi.org/10.1016/S0002-9149(99)00251-9
    Journal articles | 1999
    Professor Diane Fatkin
    McConnell BK; Jones KA; Fatkin D; Arroyo LH; Lee RT; Aristizabal O; Turnbull DH; Georgakopoulos D; Kass D; Bond M; Niimura H; Schoen FJ; Conner D; Fischman DA; Seidman CE; Seidman JG, 1999, 'Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice (vol 104, pg 1235, 1999)', JOURNAL OF CLINICAL INVESTIGATION, vol. 104, pp. 1771 - 1771, http://dx.doi.org/10.1172/JCI7377C1
    Journal articles | 1999
    Professor Diane Fatkin
    McConnell BK; Jones KA; Fatkin D; Arroyo LH; Lee RT; Aristizabal O; Turnbull DH; Georgakopoulos D; Kass D; Bond M; Niimura H; Schoen FJ; Conner D; Fischman DA; Seidman CR; Seidman JG, 1999, 'Erratum: Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice (Journal of Clinical Investigation (1999) 104 (1235-1244))', Journal of Clinical Investigation, vol. 104, pp. 1771, http://dx.doi.org/10.1172/jci7377c1
    Journal articles | 1998
    Professor Diane Fatkin
    Benson DW; Sharkey A; Fatkin D; Lang P; Basson CT; McDonough B; Strauss AW; Seidman JG; Seidman CE, 1998, 'Reduced penetrance, variable expressivity, and genetic heterogeneity of familial atrial septal defects', Circulation, vol. 97, pp. 2043 - 2048, http://dx.doi.org/10.1161/01.CIR.97.20.2043
    Journal articles | 1998
    Professor Diane Fatkin
    Fatkin D; Roy P; Sindone A; Feneley MP, 1998, 'Rapid onset and dissipation of left atrial spontaneous echo contrast during percutaneous balloon mitral valvotomy', American Heart Journal, vol. 135, pp. 609 - 613, http://dx.doi.org/10.1016/S0002-8703(98)70275-3
    Journal articles | 1997
    Professor Diane Fatkin
    Fatkin D; Feneley MP; Klein AL; Murray RD; Grimm RA; D'Sa A; Leung DY; Black IW; Thomas JD, 1997, 'Qualitative or quantitative assessment of spontaneous echo contrast? [2]', Journal of the American College of Cardiology, vol. 29, pp. 222 - 224, http://dx.doi.org/10.1016/S0735-1097(97)87151-3
    Journal articles | 1997
    Professor Diane Fatkin
    Fatkin D; Loupas T; Low J; Feneley M, 1997, 'Inhibition of red cell aggregation prevents spontaneous echocardiographic contrast formation in human blood', Circulation, vol. 96, pp. 889 - 896, http://dx.doi.org/10.1161/01.CIR.96.3.889
    Journal articles | 1997
    Professor Diane Fatkin
    Fatkin D; Loupas T; Feneley MP, 1997, 'Direct effects of DC cardioversion on blood echogenicity: An in vitro study', Ultrasound in Medicine and Biology, vol. 23, pp. 135 - 142, http://dx.doi.org/10.1016/S0301-5629(96)00169-X
    Journal articles | 1996
    Professor Diane Fatkin
    Fatkin D; Feneley M, 1996, 'Stratification of thromboembolic risk of atrial fibrillation by transthoracic echocardiography and transesophageal echocardiography: The relative role of left atrial appendage function, mitral valve disease, and spontaneous echocardiographic contrast', Progress in Cardiovascular Diseases, vol. 39, pp. 57 - 68, http://dx.doi.org/10.1016/S0033-0620(96)80041-7
    Journal articles | 1996
    Professor Diane Fatkin
    Fatkin D; Scalia G; Jacobs N; Burstow D; Leung DY; Walsh WF; Feneley MP, 1996, 'Accuracy of biplane transesophageal echocardiography in detecting left atrial thrombus', American Journal of Cardiology, vol. 77, pp. 321 - 323, http://dx.doi.org/10.1016/S0002-9149(97)89406-4
    Journal articles | 1996
    Professor Diane Fatkin
    Fatkin D; Feneley MP, 1996, 'Patterns of Doppler-measured blood flow velocity in the normal and fibrillating human left atrial appendage', American Heart Journal, vol. 132, pp. 995 - 1003, http://dx.doi.org/10.1016/S0002-8703(96)90012-5
    Journal articles | 1996
    Professor Diane Fatkin
    Fatkin D; Scalia G; Jacobs N; Burstow D; Leung DY; et A, 1996, 'Diagnostic accuracy of biplane transesophageal echocardiography for left atrial thrombus', Diagnostic accuracy of biplane transesophageal echocardiography for left atrial thrombus, vol. 77, pp. 321 - 323, http://dx.doi.org/10.1016/S0002-9149(97)89406-4
    Journal articles | 1995
    Professor Diane Fatkin
    Fatkin D; Loupas T; Jacobs N; Feneley MP, 1995, 'Quantification of blood echogenicity: evalutation of a semiquantitative method of grading spontaneous echo contrast', Ultrasound in Medicine and Biology, vol. 21, pp. 1191 - 1198, http://dx.doi.org/10.1016/0301-5629(95)02006-3
    Journal articles | 1995
    Professor Diane Fatkin
    Black ID; Fatkin D; Sagar K; Khandheria B; Leung DY; et A, 1995, 'Embolism after cardioversion of atrial fibrillation', Cardiology Board Review, vol. 12, pp. 17 - 20
    Journal articles | 1995
    Professor Diane Fatkin
    FATKIN D; LOUPAS T; LOW J; FENELEY MP, 1995, 'INHIBITION OF RED-CELL AGGREGATION PREVENTS SPONTANEOUS ECHOCARDIOGRAPHIC CONTRAST FORMATION IN HUMAN BLOOD', CIRCULATION, vol. 92, pp. 105 - 105, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995TB48000102&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1994
    Professor Diane Fatkin
    Fatkin D; Kelly R; Feneley MP, 1994, 'Left atrial appendage blood velocity and thromboembolic risk in patients with atrial fibrillation', Journal of the American College of Cardiology, vol. 24, pp. 1429 - 1430, http://dx.doi.org/10.1016/0735-1097(94)90133-3
    Journal articles | 1994
    Professor Diane Fatkin
    Fatkin D; Herbert E; Feneley MP, 1994, 'Hematologic correlates of spontaneous echo contrast in patients with atrial fibrillation and implications for thromboembolic risk', The American Journal of Cardiology, vol. 73, pp. 672 - 676, http://dx.doi.org/10.1016/0002-9149(94)90932-6
    Journal articles | 1994
    Professor Diane Fatkin
    Fatkin D; Kelly RP; Feneley MP, 1994, 'Relations between left atrial appendage blood flow velocity, spontaneous echocardiographic contrast and thromboembolic risk in vivo', Journal of the American College of Cardiology, vol. 23, pp. 961 - 969, http://dx.doi.org/10.1016/0735-1097(94)90644-0
    Journal articles | 1994
    Professor Diane Fatkin
    Black ID; Fatkin D; Sagar K; Khandheria B; Leung DY; Galloway J; Feneley MP; Walsh WF; Grimm R; Stollberger C, 1994, 'Exclusion of atrial thrombus by transesophageal echocardiography does not preclude embolism after cardioversion of atrial fibrillation: a multicenter study', Circulation, vol. 89, pp. 2509 - 2513, http://dx.doi.org/10.1161/?01.CIR.89.6.2509
    Journal articles | 1994
    Professor Diane Fatkin
    FATKIN D; CARROLL G; KUCHAR D; FENELEY MP, 1994, 'Thromboembolic complications after pharmacologic cardioversion of atrial fibrillation', Australian and New Zealand Journal of Medicine, vol. 24, pp. 584 - 585, http://dx.doi.org/10.1111/j.1445-5994.1994.tb01771.x
    Journal articles | 1994
    Professor Diane Fatkin
    FATKIN D; LOUPAS T; LOW J; FENELEY M, 1994, 'RED-CELLS AND PLASMA-PROTEINS ARE REQUIRED FOR ECHOCARDIOGRAPHIC CONTRAST FORMATION IN HUMAN BLOOD', JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, pp. A128 - A128, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994PP51800502&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1994
    Professor Diane Fatkin
    Fatkin D; Kuchar DL; Thorburn CW; Feneley MP, 1994, 'Transesophageal echocardiography before and during direct current cardioversion of atrial fibrillation: Evidence for "atrial stunning" as a mechanism of thromboembolic complications', Journal of the American College of Cardiology, vol. 23, pp. 307 - 316, http://dx.doi.org/10.1016/0735-1097(94)90412-X
    Journal articles | 1994
    Professor Diane Fatkin
    Frei B; Lynch SM; Jialal I; Grundy SM; Huet B; Black IW; Fatkin D; Sagar KB; Khandheria BK; Leung DY; Galloway JM; Feneley MP; Walsh WF; Grimm RA; Stollberger C; Verhorst PMJ; Klein AL; Manning WJ; Silverman DI; Douglas PS, 1994, 'Effects of combined supplementation with antioxidants on low-density lipoprotein oxidation [2]', Circulation, vol. 90, pp. 3119 - 3122, http://dx.doi.org/10.1161/01.cir.90.6.3119
    Journal articles | 1994
    Professor Diane Fatkin
    FATKIN D; FENELEY MP, 1994, 'SPONTANEOUS ECHO CONTRAST AND THROMBOEMBOLIC RISK IN PATIENTS WITH ATRIAL-FIBRILLATION - A PROSPECTIVE-STUDY', CIRCULATION, vol. 90, pp. 225 - 225, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994PN41701240&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1993
    Professor Diane Fatkin
    Fatkin D; Roy P; Morgan JJ; Feneley MP, 1993, 'Percutaneous balloon mitral valvotomy with the Inoue single-balloon catheter: Commissural morphology as a determinant of outcome', Journal of the American College of Cardiology, vol. 21, pp. 390 - 397, http://dx.doi.org/10.1016/0735-1097(93)90680-Y
    Journal articles | 1993
    Professor Diane Fatkin
    BLACK IW; FATKIN D; SAGAR KB; LEUNG DY; GALLOWAY JM; FENELEY MP; WALSH WF; GRIMM RA; KLEIN AL, 1993, 'DOES EXCLUSION OF ATRIAL THROMBUS BY TRANSESOPHAGEAL ECHOCARDIOGRAPHY PRECLUDE EMBOLISM AFTER CARDIOVERSION - A MULTICENTER STUDY', CIRCULATION, vol. 88, pp. 314 - 314, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993MA68201717&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1992
    Professor Diane Fatkin
    FATKIN D; HERBERT E; DOWNS K; FENELEY M, 1992, 'HEMATOLOGICAL CORRELATES OF SPONTANEOUS ECHO CONTRAST', CIRCULATION, vol. 86, pp. 397 - 397, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1992JT66001605&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 1991
    Professor Diane Fatkin
    Fatkin D; Thorburn C; Hickie J; Kuchar D, 1991, 'Arrhythmogenic right ventricular dysplasia', Australian and New Zealand Journal of Medicine, vol. 21, pp. 451 - 453, http://dx.doi.org/10.1111/j.1445-5994.1991.tb01352.x
    Journal articles | 1980
    Professor Diane Fatkin
    Davey DF; Dulhunty AF; Fatkin D, 1980, 'Glycerol treatment in mammalian skeletal muscle', The Journal of Membrane Biology, vol. 53, pp. 223 - 233, http://dx.doi.org/10.1007/BF01868828
  • Reports | 2016
    Professor Diane Fatkin
    Wang LW; Huttner IG; Santiago CF; Fatkin D; Martin I, 2016, Bradycardia in Zebrafish Heart Failure: A True Physiological Response or Anesthetic-Induced Red Herring?, United States, http://dx.doi.org/10.1089/zeb.2016.1367, https://www.ncbi.nlm.nih.gov/pubmed/27676282
  • Conference Abstracts | 2020
    Professor Diane Fatkin
    Patel P; Ito K; Willcox JAL; Gorham JM; DePalma S; Lam L; Haghighi A; Sharma A; McDonough B; Johnson R; Fatkin D; Seidman C; Seidman J, 2020, 'SEQUENCE VARIANTS IN TITIN CAUSING SPLICING DEFECTS AND CARDIOMYOPATHY: INSIGHTS FOR GENE BASED DIAGNOSIS AND NORMAL PHYSIOLOGY', in Journal of the American College of Cardiology, Elsevier BV, Vol. 75, pp. 663 - 663, http://dx.doi.org/10.1016/s0735-1097(20)31290-0
    Conference Abstracts | 2019
    Professor Diane Fatkin
    Santiago C; Huttner I; Fatkin D, 2019, 'Chronic alcohol exposure exacerbates cardiac dysfunction in TTNtv-related dilated cardiomyopathy', in JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, ELSEVIER SCI LTD, Beijing, PEOPLES R CHINA, Vol. 140, pp. 23 - 23, presented at 23rd World Congress of the International-Society-for-Heart-Research (ISHR), Beijing, PEOPLES R CHINA, 03 June 2019 - 06 June 2019, http://dx.doi.org/10.1016/j.yjmcc.2019.11.053
    Conference Abstracts | 2019
    Professor Diane Fatkin
    McGrath-Cadell L; Hesselson S; Iismaa SE; Mishra K; Wong CMY; Fatkin D; Dunwoodie SL; Harvey R; Holloway CJ; Muller DWM; Giannoulatou E; Graham RM, 2019, 'Familial clustering of spontaneous coronary artery dissection', in EUROPEAN HEART JOURNAL, OXFORD UNIV PRESS, Paris, FRANCE, Vol. 40, pp. 3414 - 3414, presented at Congress of the European-Society-of-Cardiology (ESC) / World Congress of Cardiology, Paris, FRANCE, 31 August 2019 - 04 September 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000507313003083&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Professor Diane Fatkin
    Bagnall RD; Ingles J; Dinger ME; Cowley MJ; Barratt-Ross S; Minoche AE; Lal S; Turner C; Colley A; Rajagopalan S; Berman Y; Ronan A; Fatkin D; Semsarian C, 2018, 'Whole genome sequencing improves genetic testing outcomes in hypertrophic cardiomyopathy', in EUROPEAN JOURNAL OF HUMAN GENETICS, NATURE PUBLISHING GROUP, Milan, ITALY, Vol. 27, pp. 843 - 844, presented at 51st Conference of the European-Society-of-Human-Genetics (ESHG) in conjunction with the European Meeting on Psychosocial Aspects of Genetics (EMPAG), Milan, ITALY, 16 June 2018 - 19 June 2018, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000489313106185&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Professor Diane Fatkin
    Wang LW; Keogh AM; Macdonald PS; Jabbour A; Kotlyar E; Feneley MP; Fatkin D; Hayward CS, 2015, 'Right ventricular function is a powerful independent predictor of adverse heart failure outcomes', in EUROPEAN HEART JOURNAL, OXFORD UNIV PRESS, London, ENGLAND, Vol. 36, pp. 830 - 831, presented at Congress of the European-Society-of-Cardiology (ESC), London, ENGLAND, 29 August 2015 - 02 September 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000361205105553&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2014
    Professor Diane Fatkin
    Fatkin D, 2014, 'EVOLUTION OF THE GENETICS REVOLUTION IN FAMILIAL CARDIOMYOPATHIES', in INTERNAL MEDICINE JOURNAL, WILEY-BLACKWELL, pp. 16 - 16, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000335884600064&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2014
    Professor Diane Fatkin
    Ito K; McDonough B; Gorham JM; DeParma SR; Adler EE; Mohiuddin SM; Fatkin D; Seidman JG; Seidman CE, 2014, 'A lamin A/C Synonymous Mutation Creates a Novel Splice Site and Causes Progressive Atrioventricular Conduction Defect', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209790204220&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Professor Diane Fatkin
    Yu Z-Y; Tan J-C; McMahon AC; Lismaa SF; Xiao X-H; Kesteven SH; Reichelt ME; Mohl MC; Dai Y; Sketchley AE; Yanq LL; Gong H; Smith NJ; Fatkin D; Allen D; Head SI; Graham RM; Feneley MP, 2013, 'Critical Role of RhoA/ROCK Signaling in Cardiac Contractility', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Dallas, TX, presented at Scientific Sessions and Resuscitation Science Symposium of the American-Heart-Association, Dallas, TX, 16 November 2013 - 17 November 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000332162903138&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2013
    Professor Diane Fatkin
    Olesen M; Liang B; Soka M; Larsen AP; Knop FK; Wang F; Nielsen JB; Andersen MN; Humphreys D; Mann SA; Vandenberg JI; Svendsen JH; Haunso S; Preiss T; Seebohm G; Olesen S-P; Schmitt N; Fatkin D, 2013, 'TASK-1 potassium channel mutations in atrial fibrillation', in EUROPEAN HEART JOURNAL, OXFORD UNIV PRESS, Amsterdam, NETHERLANDS, Vol. 34, pp. 642 - 642, presented at Congress of the European-Society-of-Cardiology (ESC), Amsterdam, NETHERLANDS, 31 August 2013 - 04 September 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000327744604084&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Professor Diane Fatkin
    Nikolova-Krstevski V; Wagner S; Friedrich O; Fatkin D, 2013, 'Transient Receptor Potential Channel 6 (TRPC6) Is An Important Mediator Of Mechanical Stretch Responses In The Atrial Endocardial Endothelium', in CIRCULATION RESEARCH, LIPPINCOTT WILLIAMS & WILKINS, Las Vegas, NV, presented at Scientific Sessions of the American-Heart-Association on Basic Cardiovascular Sciences, Las Vegas, NV, 22 July 2013 - 25 July 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000332063200041&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2011
    Professor Diane Fatkin
    Tong J; Vidal C; Li W; Yeo L; Fatkin D; Duque G, 2011, 'Lamin A/C Deficiency is Associated with Fat Infiltration of Muscle and Bone: A Proposed Model of Sarco-Osteopenia.', in JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, WILEY-BLACKWELL, National Harbor, MD, pp. S78 - S78, presented at Annual Scientific Meeting on the American-Geriatrics-Society, National Harbor, MD, 11 May 2011 - 14 May 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000289524600227&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2010
    Professor Diane Fatkin
    Riveron JTG; Ghosh TK; Pope M; Eason J; BuLock F; Thomborough C; Kirk EP; Fatkin D; Feneley MP; Harvey RP; Armour JAL; Brook JD, 2010, 'alpha,-cardiac myosin heavy chain (MYH6) mutations affecting myofibril formation are associated with congenital heart defects', in JOURNAL OF MEDICAL GENETICS, B M J PUBLISHING GROUP, Warwick, RI, pp. S76 - S76, presented at British Human Genetics Conference, Warwick, RI, 06 September 2010 - 08 September 2010, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000283762600155&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2009
    Professor Diane Fatkin
    Duque G; Li WJ; Yeo L; Fatkin D, 2009, 'Exercise has a Deleterious Effect on Bone Quality in Lamin A/C-Deficient Mice', in Journal of the American Geriatrics Society, Blackwell Publishing Inc, Malden, MA, pp. S11 - S11, presented at American Geriatrics Society (AGS) 2009 Annual Scientific Meeting, Chicago, Illinois, USA, 29 April 2009 - 03 May 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000264611900029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2008
    Professor Diane Fatkin
    Granados-Riveron J; Pope M; Eason J; BuLock F; Cox J; Thomborough C; Kirk EP; Fatkin D; Feneley MP; Harvey RP; Armour J; Brook J, 2008, 'alpha-cardiac myosin heavy chain (MYH6) mutations are associated with congenital heart defects', in Journal of Medical Genetics, B M J Publishing Group, London, England, pp. S86 - S86, presented at Journal of Medical Genetics, Univ York, York, ENGLAND, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000259436400186&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2008
    Professor Diane Fatkin
    Cannon L; Marcinlec T; Mearns BM; Graham RM; Fatkin D, 2008, 'Left Ventricular Hypertrophy Is Resistant to Inhibition of Expression of the R403Q Alpha-Myosin Heavy Chain Cardiac Hypertrophy-Inducing Mutant Protein', in Circulation, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. S423 - S423, presented at 81st Annual Scientific Session of the American-Heart-Association, New Orleans, LA, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000262104500695&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2007
    Professor Diane Fatkin
    Otway RT; Vandenberg JI; Guo G; Fatkin D, 2007, 'Interaction between a KCNQ1 mutation and cell stretch in familial atrial fibrillation', in BIOPHYSICAL JOURNAL, BIOPHYSICAL SOCIETY, Baltimore, MD, pp. 463A - 463A, presented at 51st Annual Meeting of the Biophysical-Society, Baltimore, MD, 03 March 2007 - 07 March 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000243972403011&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2000
    Professor Diane Fatkin
    Semsarian C; McConnell BK; Fatkin D; Mudd JO; Olson EN; Moskowitz I; Schoen FJ; Giewat M; Seidman CE; Seidman JG, 2000, 'Cyclosporin A and minoxidil exacerbate cardiac hypertrophy in hypertrophic cardiomyopathy via a calcium-mediated pathway', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, pp. 98 - 98, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000090072300463&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2000
    Professor Diane Fatkin
    Sasaki T; Fatkin D; Macrae C; Wolff MR; Vidaillet HJ; Darras BT; De Girolami U; Seidman JG; Seidman CE, 2000, 'Dilated cardiomyopathy, Emery-Dreifuss muscular dystrophy and partial lipodystrophy: Structure function relationships in lamin A/C', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, pp. 280 - 280, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000090072301368&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2000
    Professor Diane Fatkin
    Levy H; Schonberger J; Somkiat S; Fatkin D; MacRae E; Halpin C; Eavey R; Philbin E; Seidman JG; Seidman C, 2000, 'Dilated cardiomyopathy and sensorineural hearing loss: A heritable syndrome that maps to 6q23-24', in PEDIATRIC RESEARCH, NATURE PUBLISHING GROUP, pp. 46A - 46A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000086155300270&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1999
    Professor Diane Fatkin
    Fatkin D; McConnell BK; Jones K; Healey MJ; Mudd JO; Conner DA; Schoen FJ; Schoen J; Seidman JG; Seidman CE, 1999, 'Evaluation of cardiac structure and function in two moose models of familial hypertrophic cardiomyopathy', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, pp. 494 - 494, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000083417102599&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1999
    Professor Diane Fatkin
    Berul CI; Fatkin D; McConnell BK; Maguire CT; Gehrmann J; Rakhit A; Jones K; Seidman JG; Seidman CE, 1999, 'Electrophysiological characterization of familial hypertrophic cardiomyopathy mice with mutant myosin binding protein C gene', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, pp. 207 - 207, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000083417101071&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1999
    Professor Diane Fatkin
    Schoenberger J; Levy H; Gruenig E; Ronald E; Sangwatanaroj S; Fatkin D; Staeckler H; Halpin C; Philbin EF; Katus HA; Seidman JG; Seidman CE, 1999, 'Dilated cardiomyopathy and sensorineurinal hearing loss: A heritable syndrome, that maps to 6q23-24', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, pp. 618 - 619, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000083417103257&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1999
    Professor Diane Fatkin
    Bruneau BG; Bao ZZ; Fatkin D; Georgakopoulos D; Mudd JO; Conner DA; Schoen FJ; de Bold A; Cepko CL; Seidman JG; Seidman E, 1999, 'Disruption of the ventricle-specific homeobox gene lrx4 in mice leads to cardiac dysfunction and hypertrophy', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, pp. 347 - 348, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000083417101821&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1998
    Professor Diane Fatkin
    Gruver EJ; Fatkin D; Dodds GA; Kisslo J; Maron BJ; Seidman JG; Seidman CE, 1998, 'Familial hypertrophic cardiomyopathy and atrial fibrillation caused by Arg663His beta-cardiac myosin heavy chain mutation', in AMERICAN JOURNAL OF CARDIOLOGY, EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, BADEN BADEN, GERMANY, pp. 13H - 18H, presented at Symposium on From Increased Energy Metabolism to Cardiac Hypertrophy and Failure - Mediators and Molecular Mechanisms, BADEN BADEN, GERMANY, 25 September 1998 - 27 September 1998, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000081307900005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1998
    Professor Diane Fatkin
    McConnell BK; Jones K; Fatkin D; Arroyo LH; Lee RT; Aristizabal O; Turnbull DH; Georgakopoulos D; Kass DA, 1998, 'Mice with a mutant myosin binding protein C gene provide a model for familial hypertrophic cardiomyopathy.', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, pp. 625 - 625, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000076594403305&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1998
    Professor Diane Fatkin
    Healey MJ; Fatkin D; Arroyo LH; Lee RT; Maguire CT; Bevilacqua ML; Berul CI; Seidman JG; Seidman CE, 1998, 'Exercise and beta-blocker therapy in alpha-myosin heavy chain mutant mice with hypertrophic cardiomyopathy', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, pp. 70 - 70, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000076594400401&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1997
    Professor Diane Fatkin
    Fatkin D; Aristizabal O; Srinivasan S; Christe ME; Seidman JG; Seidman CE; Turnbull DH, 1997, 'Noninvasive in vivo assessment of cardiac function in the neonatal murine heart using high frequency (50 MHz) ultrasound backscatter microscopy', in CIRCULATION, AMER HEART ASSOC, pp. 4144 - 4144, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997YC88004110&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1997
    Professor Diane Fatkin
    Benson DW; Strauss AW; Sharkey A; Fatkin D; Schott JJ; Sangwatanaroj S; Pease WE; Basson CT; Seidman JG; Seidman CE, 1997, 'A familial atrial septal defect gene maps to chromosome 5p: Evidence for reduced gene penetrance, variable expressivity and genetic heterogeneity', in CIRCULATION, AMER HEART ASSOC, pp. 76 - 76, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997YC88000076&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 1997
    Professor Diane Fatkin
    Fatkin D; Christe ME; Aristizabal O; Schoen FJ; Turnbull DH; Seidman CE; Seidman JG, 1997, 'Characterization of cardiac structure and function in the homozygous alpha-myosin heavy chain (Arg403Gln) mutant mouse', in CIRCULATION, AMER HEART ASSOC, pp. 3186 - 3186, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997YC88003167&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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