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Mr Dinesh Subedi

Mr Dinesh Subedi

Adjunct Lecturer
Medicine & Health
School of Optometry and Vision Science

Dr. Dinesh Subedi is also a Postdoctoral Researcher at Monash University in Australia. He has a background in medical microbiology and bioinformatics. His current research focuses on using bacteriophages to treat infections caused by hospital-acquired (nosocomial) pathogens. Dr. Subedi completed his Ph.D. at the University of New South Wales (UNSW), where he studied how Pseudomonas aeruginosa becomes resistant to antibiotics and holds a master's degree in medical microbiology from Nepal. He is also an Adjunct Lecturer at UNSW School of Optometry & Vision Science. 

 
E-mail
d.subedi@unsw.edu.au
Location
UNSW School of Optometry & Vision Science North Wing Rupert Myers Building Gate 14 Barker Street UNSW Sydney NSW 2052
  • Journal articles | 2025
    Landry SA; Jamriska M; Menon VJ; Lee LYY; Magnin-Bougma I; Subedi D; Barr JJ; Monty J; Kevin K; Gunatilaka A; Delaire M; Marks GB; Stewardson AJ; Morawska L; Edwards BA; Majumdar SS; Subbarao K; Joosten SA, 2025, 'Ultraviolet radiation vs air filtration to mitigate virus laden aerosol in an occupied clinical room', Journal of Hazardous Materials, 487, http://dx.doi.org/10.1016/j.jhazmat.2025.137211
    Journal articles | 2023
    Lee LYY; Landry SA; Jamriska M; Subedi D; Joosten SA; Barr JJ; Brown R; Kevin K; Schofield R; Monty J; Subbarao K; McGain F, 2023, 'Quantifying the reduction of airborne infectious viral load using a ventilated patient hood', Journal of Hospital Infection, 136, pp. 110 - 117, http://dx.doi.org/10.1016/j.jhin.2023.04.009
    Journal articles | 2023
    Subedi D; Fang T; Bhusal RP; Willcox M, 2023, 'Editorial: Bacteriophages to treat infections with multidrug resistant pathogens', Frontiers in Medicine, 10, http://dx.doi.org/10.3389/fmed.2023.1348463
    Journal articles | 2022
    Bhusal RP; Barr JJ; Subedi D, 2022, 'A metabolic perspective into antimicrobial tolerance and resistance', The Lancet Microbe, 3, pp. e160 - e161, http://dx.doi.org/10.1016/S2666-5247(22)00006-4
    Journal articles | 2022
    Gordillo Altamirano FL; Kostoulias X; Subedi D; Korneev D; Peleg AY; Barr JJ, 2022, 'Phage-antibiotic combination is a superior treatment against Acinetobacter baumannii in a preclinical study', eBioMedicine, 80, http://dx.doi.org/10.1016/j.ebiom.2022.104045
    Journal articles | 2022
    Landry SA; Subedi D; Barr JJ; MacDonald MI; Dix S; Kutey DM; Mansfield D; Hamilton GS; Edwards BA; Joosten SA, 2022, 'Fit-Tested N95 Masks Combined With Portable High-Efficiency Particulate Air Filtration Can Protect Against High Aerosolized Viral Loads Over Prolonged Periods at Close Range', Journal of Infectious Diseases, 226, pp. 199 - 207, http://dx.doi.org/10.1093/infdis/jiac195
    Journal articles | 2022
    Landry SA; Subedi D; MacDonald MI; Dix S; Kutey DM; Barr JJ; Mansfield D; Hamilton GS; Edwards BA; Joosten SA, 2022, 'Point of emission air filtration enhances protection of healthcare workers against skin contamination with virus aerosol', Respirology, 27, pp. 465 - 468, http://dx.doi.org/10.1111/resp.14227
    Journal articles | 2022
    Rayamajhee B; Sharma S; Willcox M; Henriquez FL; Rajagopal RN; Shrestha GS; Subedi D; Bagga B; Carnt N, 2022, 'Assessment of genotypes, endosymbionts and clinical characteristics of Acanthamoeba recovered from ocular infection', BMC Infectious Diseases, 22, pp. 757, http://dx.doi.org/10.1186/s12879-022-07741-4
    Journal articles | 2022
    Rayamajhee B; Willcox MDP; Henriquez FL; Petsoglou C; Subedi D; Carnt N, 2022, 'Acanthamoeba, an environmental phagocyte enhancing survival and transmission of human pathogens', Trends in Parasitology, 38, pp. 975 - 990, http://dx.doi.org/10.1016/j.pt.2022.08.007
    Journal articles | 2022
    Wang X; Sun Y; Subedi D; Gong Q; Huang H; Li J; Wang Y; Ren J, 2022, 'Hcp Proteins of the Type VI Secretion System Promote Avian Pathogenic E. coli DE205B (O2:K1) to Induce Meningitis in Rats', Life, 12, http://dx.doi.org/10.3390/life12091353
    Journal articles | 2022
    Wang Y; Subedi D; Li J; Wu J; Ren J; Xue F; Dai J; Barr JJ; Tang F, 2022, 'Phage Cocktail Targeting STEC O157:H7 Has Comparable Efficacy and Superior Recovery Compared with Enrofloxacin in an Enteric Murine Model', Microbiology Spectrum, 10, http://dx.doi.org/10.1128/spectrum.00232-22
    Journal articles | 2021
    Carnt NA; Pang I; Burdon KP; Calder V; Dart JK; Subedi D; Hardcastle AJ, 2021, 'Innate and adaptive gene single nucleotide polymorphisms associated with susceptibility of severe inflammatory complications in acanthamoeba keratitis', Investigative Ophthalmology and Visual Science, 62, pp. 33 - 33, http://dx.doi.org/10.1167/IOVS.62.3.33
    Journal articles | 2021
    Gordillo Altamirano F; Forsyth JH; Patwa R; Kostoulias X; Trim M; Subedi D; Archer SK; Morris FC; Oliveira C; Kielty L; Korneev D; O’Bryan MK; Lithgow TJ; Peleg AY; Barr JJ, 2021, 'Bacteriophage-resistant Acinetobacter baumannii are resensitized to antimicrobials', Nature Microbiology, 6, pp. 157 - 161, http://dx.doi.org/10.1038/s41564-020-00830-7
    Journal articles | 2021
    Hossain L; Maliha M; Barajas-Ledesma R; Kim J; Putera K; Subedi D; Tanner J; Barr JJ; Banaszak Holl MM; Garnier G, 2021, 'Engineering laminated paper for SARS-CoV-2 medical gowns', Polymer, 222, http://dx.doi.org/10.1016/j.polymer.2021.123643
    Journal articles | 2021
    Joosten S; Barr J; MacDonald M; Subedi D; Mansfield D; Hamilton G; Edwards B; Landry S, 2021, 'Virus aerosol propagation by continuous positive airways pressure (CPAP) is proportional to mask leak', Infection, Disease & Health, 26, pp. S5 - S6, http://dx.doi.org/10.1016/j.idh.2021.09.019
    Journal articles | 2021
    Landry SA; Barr JJ; MacDonald MI; Subedi D; Mansfield D; Hamilton GS; Edwards BA; Joosten SA, 2021, 'Viable virus aerosol propagation by positive airway pressure circuit leak and mitigation with a ventilated patient hood', European Respiratory Journal, 57, http://dx.doi.org/10.1183/13993003.03666-2020
    Journal articles | 2021
    Ozkan J; Coroneo M; Sandbach J; Subedi D; Willcox M; Thomas T, 2021, 'Bacterial contamination of intravitreal needles by the ocular surface microbiome', Ocular Surface, 19, pp. 169 - 175, http://dx.doi.org/10.1016/j.jtos.2020.05.010
    Journal articles | 2021
    Peguda HK; Mahbub SB; Sherpa TD; Subedi D; Habibalahi A; Anwer AG; Gu Z; Willcox MDP; Goldys EM; Carnt NA, 2021, 'The autofluorescence patterns of acanthamoeba castellanii, pseudomonas aeruginosa and staphylococcus aureus: Effects of antibiotics and tetracaine', Pathogens, 10, pp. 894, http://dx.doi.org/10.3390/pathogens10070894
    Journal articles | 2021
    Rayamajhee B; Subedi D; Peguda HK; Willcox MD; Henriquez FL; Carnt N, 2021, 'A systematic review of intracellular microorganisms within acanthamoeba to understand potential impact for infection', Pathogens, 10, pp. 1 - 25, http://dx.doi.org/10.3390/pathogens10020225
    Journal articles | 2021
    Subedi D; Barr JJ, 2021, 'Temporal stability and genetic diversity of 48-year-old T-series phages', mSystems, 6, http://dx.doi.org/10.1128/MSYSTEMS.00990-20
    Journal articles | 2020
    Adhikari N; Subedi D, 2020, 'The alarming outbreaks of dengue in Nepal', Tropical Medicine and Health, 48, http://dx.doi.org/10.1186/s41182-020-0194-1
    Journal articles | 2020
    Carnt NA; Subedi D; Connor S; Kilvington S, 2020, 'The relationship between environmental sources and the susceptibility of Acanthamoeba keratitis in the United Kingdom', PLoS ONE, 15, http://dx.doi.org/10.1371/journal.pone.0229681
    Journal articles | 2020
    Carnt NA; Subedi D; Lim AW; Lee R; Mistry P; Badenoch PR; Kilvington S; Dutta D, 2020, 'Prevalence and seasonal variation of Acanthamoeba in domestic tap water in greater Sydney, Australia', Clinical and Experimental Optometry, 103, pp. 782 - 786, http://dx.doi.org/10.1111/cxo.13065
    Journal articles | 2020
    Khan M; Summers S; Rice SA; Stapleton F; Willcox MDP; Subedi D, 2020, 'Acquired fluoroquinolone resistance genes in corneal isolates of Pseudomonas aeruginosa', Infection, Genetics and Evolution, 85, pp. 104574, http://dx.doi.org/10.1016/j.meegid.2020.104574
    Journal articles | 2020
    Landry S; Barr J; MacDonald M; Subedi D; Mansfield D; Hamilton G; Edwards B; Joosten S, 2020, 'Viable virus aerosol propagation by PAP circuit leak and mitigation with a ventilated patient hood – a model for improving health care worker safety in the COVID-19 pandemic', , http://dx.doi.org/10.1101/2020.09.04.20187922
    Journal articles | 2020
    Rayamajhee B; Subedi D; Won S; Kim J; Vijay A; Tan J; Henriquez FL; Willcox M; Carnt NA; Showyin J, 2020, 'Investigating domestic shower settings as a risk factor for acanthamoeba keratitis', Water (Switzerland), 12, pp. 1 - 12, http://dx.doi.org/10.3390/w12123493
    Journal articles | 2020
    Singh J; Subedi D; Gordillo-Altamirano F; Patwa R; Selvadurai H; Barr JJ; Khatami A, 2020, 'ePS6.06 Isolating and characterising phages against Pseudomonas aeruginosa and Staphylococcus aureus in children with cystic fibrosis', Journal of Cystic Fibrosis, 19, pp. S53 - S54, http://dx.doi.org/10.1016/s1569-1993(20)30334-9
    Journal articles | 2020
    Subedi D; Barr J, 2020, 'Temporal stability and genetic diversity of 48-year old T-series phages', , http://dx.doi.org/10.1101/2020.09.24.312751
    Journal articles | 2019
    Carnt N; Subedi D; Lim AW; Lee R; Mistry P; Dutta D, 2019, 'The prevalence and seasonal variation of Acanthamoeba in domestic tap-water in greater Sydney region, Australia', Contact Lens and Anterior Eye, 42, pp. e37 - e37, http://dx.doi.org/10.1016/j.clae.2019.10.124
    Journal articles | 2019
    Subedi D; Kohli GS; Vijay AK; Willcox M; Rice SA, 2019, 'Accessory genome of the multi-drug resistant ocular isolate of Pseudomonas aeruginosa PA34', PLoS ONE, 14, pp. e0215038, http://dx.doi.org/10.1371/journal.pone.0215038
    Journal articles | 2019
    Subedi D; Vijay AK; Rice SA; Willcox M, 2019, 'Cytotoxic factor influencing acquired antimicrobial resistance in Pseudomonas aeruginosa', Microbiology Australia, 40, pp. 161 - 164, http://dx.doi.org/10.1071/MA19048
    Journal articles | 2018
    Subedi D; Kohli GS; Vijay AK; Willcox M; Rice SA, 2018, 'Accessory genome contributes to the virulence and resistance of the ocular isolate of Pseudomonas aeruginosa: A complete genome analysis', , pp. 497974, http://dx.doi.org/10.1101/497974
    Journal articles | 2018
    Subedi D; Vijay AK; Kohli GS; Rice SA; Willcox M, 2018, 'Comparative genomics of clinical strains of Pseudomonas aeruginosa strains isolated from different geographic sites', Scientific Reports, 8, pp. 15668, http://dx.doi.org/10.1038/s41598-018-34020-7
    Journal articles | 2018
    Subedi D; Vijay AK; Kohli GS; Rice SA; Willcox M, 2018, 'Nucleotide sequence analysis of NPS-1 β-lactamase and a novel integron (In1427)-carrying transposon in an MDR Pseudomonas aeruginosa keratitis strain', Journal of Antimicrobial Chemotherapy, 73, pp. 1724 - 1726, http://dx.doi.org/10.1093/jac/dky073
    Journal articles | 2018
    Subedi D; Vijay AK; Willcox M, 2018, 'Overview of mechanisms of antibiotic resistance in Pseudomonas aeruginosa: an ocular perspective', Clinical and Experimental Optometry, 101, pp. 162 - 171, http://dx.doi.org/10.1111/cxo.12621
    Journal articles | 2018
    Subedi D; Vijay AK; Willcox M, 2018, 'Study of disinfectant resistance genes in ocular isolates of pseudomonas Aeruginosa', Antibiotics, 7, pp. 88, http://dx.doi.org/10.3390/antibiotics7040088
    Journal articles | 2016
    Subedi D; Taylor-Robinson AW, 2016, 'Epidemiology of Dengue in Nepal: History of incidence, current prevalence and strategies for future control', Journal of Vector Borne Diseases, 53, pp. 1 - 7
  • Preprints | 2025
    Gordillo Altamirano FL; Subedi D; Beiers M; Bucher MJ; Dahlman S; Patel DM; Parker M; Korneev D; Pragastis K; Wisniewski J; Rees C; Ramshaw H; Khan S; Gardiner B; Hammerschlag Y; Keating D; Kotsimbos T; Hawkey J; Barr JJ; Peleg AY, 2025, Mechanistic insights and clinical implications of cross-reactive anti-prophage antibodies and bacterial heteroresistance on phage therapeutic failure, http://dx.doi.org/10.1101/2025.04.22.650118
    Preprints | 2024
    Subedi D; Gordillo Altamirano F; Deehan R; Perera A; Patwa R; Kostoulias X; Korneev D; Blakeway L; Macesic N; Peleg AY; Barr JJ, 2024, Rational Design of Frontline Institutional Phage Cocktail for the Treatment of NosocomialEnterobacter cloacaeComplex Infections, http://dx.doi.org/10.1101/2024.06.30.601436
    Preprints | 2023
    Dahlman S; Avellaneda-Franco L; Kett C; Subedi D; Young R; Gould J; Rutten E; Gulliver E; Turkington CJR; Nezam-Abadi N; Grasis J; Lyras D; Edwards R; Forster S; Barr J, 2023, Temperate gut phages are prevalent, diverse, and predominantly inactive, http://dx.doi.org/10.1101/2023.08.17.553642
    Conference Papers | 2022
    Joosten S; Landry S; Subedi D; Barr J; Macdonald MI; Dix S; Kutey DM; Mansfield D; Hamilton G; Edwards BA, 2022, 'Personal Protective Equipment Does Not Sufficiently Protect Against Virus Aerosol Unless Combined with Air Purification', in B57. CUTTING EDGE COVID RESEARCH, American Thoracic Society, pp. A3129 - A3129, presented at American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA, http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3129
    Preprints | 2022
    Lee LYY; Landry S; Jamriska M; Subedi D; Joosten S; Barr J; Brown R; Kevin K; Schofield R; Monty J; Subbarao K; McGain F, 2022, Efficacy of a patient isolation hood in reducing exposure to airborne infectious virus in a simulated healthcare setting, http://dx.doi.org/10.1101/2022.07.24.22277784
    Preprints | 2021
    Landry S; Subedi D; Barr J; MacDonald M; Dix S; Kutey D; Mansfield D; Hamilton G; Edwards B; Joosten S, 2021, Personal protective equipment does not sufficiently protect against virus aerosol unless combined with advanced air purification or ventilation techniques, http://dx.doi.org/10.1101/2021.09.02.21263008
    Preprints | 2021
    Landry SA; Subedi D; MacDonald MI; Dix S; Kutey D; Barr J; Mansfield D; Hamilton G; Edwards B; Joosten S, 2021, Point of emission air filtration enhances protection of health care workers against skin contamination with virus aerosol, http://dx.doi.org/10.1101/2021.08.15.21261997
    Preprints | 2020
    Altamirano FG; Forsyth JH; Patwa R; Kostoulias X; Trim M; Subedi D; Archer S; Morris FC; Oliveira C; Kielty L; Korneev D; O’Bryan MK; Lithgow TJ; Peleg AY; Barr JJ, 2020, Bacteriophages targetingAcinetobacter baumanniicapsule induce antimicrobial resensitization, http://dx.doi.org/10.1101/2020.02.25.965590
    Conference Papers | 2020
    Carnt NA; Pang I; Burdon KP; Calder VL; Dart J; Subedi D; Hardcastle AJ, 2020, 'The association of Interleukin 8 gene SNP with severe inflammatory complications in contact lens wearers experiencing Acanthamoeba Keratitis', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, ELECTR NETWORK, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), ELECTR NETWORK, 01 May 2020 - 07 May 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000554528302222&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints | 2020
    Khan M; Summers S; Rice SA; Stapleton F; Willcox MDP; Subedi D, 2020, Acquired fluoroquinolone resistance genes in corneal isolates ofPseudomonas aeruginosa, http://dx.doi.org/10.1101/2020.05.17.100396
    Conference Papers | 2020
    Peguda HK; Sherpa TD; Subedi D; Mahbub S; Goldys EM; Willcox M; Carnt NA, 2020, 'The effect on the autofluorescence signal of corneal microorganisms with common topical drugs', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, ELECTR NETWORK, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), ELECTR NETWORK, 01 May 2020 - 07 May 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000554495700302&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Presentations | 2017
    Subedi D; Vijay A; Rice S; Willcox M; Kohli G, (ed.), 2017, 'Association between pathogenic factors and antibiotic resistance in Pseudomonas aeruginosa', presented at BacPath 14, Adelaide, 25 September 2017 - 28 September 2017, http://dx.doi.org/10.1371/journal.pone.0204936
    Preprints |
    Landry S; Barr J; MacDonald M; Subedi D; Mansfield D; Hamilton G; Edwards B; Joosten S, Viable Virus Aerosol Propagation by PAP Circuit Leak and Mitigation with a Ventilated Patient Hood – A Model for Improving Health Care Worker Safety in the COVID-19 Pandemic, http://dx.doi.org/10.2139/ssrn.3679894