Dr Dorothy Machalek is a public health epidemiologist and Senior Research Fellow. She holds a Doctorate in epidemiology, and a Master of Public Health from the University of New South Wales.
Her research focuses on improving control of globally significant sexually transmitted infections (STIs) including human papillomavirus (HPV) the primary cause of cervical cancer, the fourth-most common malignancy in women globally; and Mycoplasma genitalium (M. genitalium), an emerging STI proving difficult to control due to high levels of antibiotic resistance.
Dr Machalek leads a National HPV Monitoring Program (called IMPACT), funded by the Commonwealth Department of Health. The program is evaluating the impact of Australia’s HPV vaccination program by tracking changes in HPV infection prevalence over time in different populations. She is a Chief Investigators on a world-first project that is measuring the impact of one and two-dose HPV vaccine schedules in South Africa, co-funded by the NHMRC and the Bill and Melinda Gates Foundation; and is an Associate Investigator on an NHMRC Centre for Research Excellence in Cervical Cancer Control.
Dr Machalek is also leading a number of projects that aim to generate new evidence to improve the control of M. genitalium infection. This includes epidemiological investigations into the association between M. genitalium infection and disease in women, and novel surveillance methodologies for monitoring M. genitalium burden and patterns of resistance.