Dr Dorothy Ann Machalek
Senior Research Fellow

Dr Dorothy Ann Machalek

medicine-health
The Kirby Institute

Dr Dorothy Machalek is a public health epidemiologist and Senior Research Fellow. She holds a Doctorate in epidemiology, and a Master of Public Health from the University of New South Wales.

Her research focuses on improving control of globally significant sexually transmitted infections (STIs) including human papillomavirus (HPV) the primary cause of cervical cancer, the fourth-most common malignancy in women globally; and Mycoplasma genitalium (M. genitalium), an emerging STI proving difficult to control due to high levels of antibiotic resistance.

Dr Machalek leads a National HPV Monitoring Program (called IMPACT), funded by the Commonwealth Department of Health. The program is evaluating the impact of Australia’s HPV vaccination program by tracking changes in HPV infection prevalence over time in different populations. She is a Chief Investigators on a world-first project that is measuring the impact of one and two-dose HPV vaccine schedules in South Africa, co-funded by the NHMRC and the Bill and Melinda Gates Foundation; and is an Associate Investigator on an NHMRC Centre for Research Excellence in Cervical Cancer Control.  

Dr Machalek is also leading a number of projects that aim to generate new evidence to improve the control of M. genitalium infection. This includes epidemiological investigations into the association between M. genitalium infection and disease in women, and novel surveillance methodologies for monitoring M. genitalium burden and patterns of resistance.

Publications

  • Journal articles | 2021
    Dr Dorothy Ann Machalek
    Chow EPF; Tabrizi SN; Fairley CK; Wigan R; Machalek DA; Garland SM; Cornall AM; Atchison S; Hocking JS; Bradshaw CS; Balgovind P; Murray GL; Chen MY, 2021, 'Prevalence of human papillomavirus in young men who have sex with men after the implementation of gender-neutral HPV vaccination: a repeated cross-sectional study.', Lancet Infect Dis, http://dx.doi.org/10.1016/S1473-3099(20)30687-3
    Journal articles | 2021
    Dr Dorothy Ann Machalek
    Gidding HF; Machalek DA; Hendry AJ; Quinn HE; Vette K; Beard FH; Shilling HS; Hirani R; Gosbell IB; Irving DO; Hueston L; Downes M; Carlin JB; O'Sullivan MVN; Dwyer DE; Kaldor JM; Macartney K, 2021, 'Seroprevalence of SARS-CoV-2-specific antibodies in Sydney after the first epidemic wave of 2020', Medical Journal of Australia, vol. 214, pp. 179 - 185, http://dx.doi.org/10.5694/mja2.50940
    Journal articles | 2021
    Dr Dorothy Ann Machalek
    Poynten IM; Jin F; Roberts JM; Templeton DJ; Law C; Cornall AM; Molano M; MacHalek DA; Carr A; Farnsworth A; Tabrizi S; Phillips S; Fairley CK; Garland SM; Hillman RJ; Grulich AE, 2021, 'The Natural History of Anal High-grade Squamous Intraepithelial Lesions in Gay and Bisexual Men', Clinical Infectious Diseases, vol. 72, pp. 853 - 861, http://dx.doi.org/10.1093/cid/ciaa166
    Journal articles | 2021
    Dr Dorothy Ann Machalek
    Shilling H; Garland SM; Atchison S; Cornall AM; Brotherton JML; Bateson D; McNamee K; Kaldor JM; Hocking JS; Chen MY; Fairley CK; McNulty A; Bell C; Marshall L; Ooi C; Skinner SR; Murray G; Molano M; Tabrizi S; Machalek DA, 2021, 'Human papillomavirus prevalence and risk factors among Australian women 9–12 years after vaccine program introduction', Vaccine, http://dx.doi.org/10.1016/j.vaccine.2021.07.005
    Journal articles | 2021
    Dr Dorothy Ann Machalek
    Bodiyabadu K; Danielewski J; Garland SM; Machalek DA; Bradshaw CS; Birnie J; Ebeyan S; Lundgren M; Murray G, 2021, 'Detection of parC gene mutations associated with quinolone resistance in Mycoplasma genitalium: Evaluation of a multiplex real-time PCR assay', Journal of Medical Microbiology, vol. 70, http://dx.doi.org/10.1099/jmm.0.001257
    Journal articles | 2021
    Dr Dorothy Ann Machalek
    Shilling HS; Garland SM; Costa AM; Marceglia A; Fethers K; Danielewski J; Murray G; Bradshaw C; Vodstrcil L; Hocking JS; Kaldor J; Guy R; Machalek DA, 2021, 'Chlamydia trachomatis and Mycoplasma genitalium prevalence and associated factors among women presenting to a pregnancy termination and contraception clinic, 2009-2019', Sexually Transmitted Infections, http://dx.doi.org/10.1136/sextrans-2020-054695
    Journal articles | 2021
    Dr Dorothy Ann Machalek
    Brotherton JML; Wheeler C; Clifford GM; Elfström M; Saville M; Kaldor J; Machalek DA, 2021, 'Surveillance systems for monitoring cervical cancer elimination efforts: Focus on HPV infection, cervical dysplasia, cervical screening and treatment', Preventive Medicine, vol. 144, pp. 106293, http://dx.doi.org/10.1016/j.ypmed.2020.106293
    Journal articles | 2021
    Dr Dorothy Ann Machalek
    Atchison S; Shilling H; Balgovind P; Machalek DA; Hawkes D; Garland SM; Saville M; Murray G; Molano M; Danielewski J; Phillips S, 2021, 'Evaluation of the Roche MagNA Pure 96 nucleic acid extraction platform for the Seegene Anyplex II HPV28 detection assay', Journal of Applied Microbiology, http://dx.doi.org/10.1111/jam.15126
    Journal articles | 2020
    Dr Dorothy Ann Machalek
    Machalek DA; Tao Y; Shilling H; Jensen JS; Unemo M; Murray G; Chow EPF; Low N; Garland SM; Vodstrcil LA; Fairley CK; Hocking JS; Zhang L; Bradshaw CS, 2020, 'Prevalence of mutations associated with resistance to macrolides and fluoroquinolones in Mycoplasma genitalium: a systematic review and meta-analysis', The Lancet Infectious Diseases, vol. 20, pp. 1302 - 1314, http://dx.doi.org/10.1016/S1473-3099(20)30154-7
    Journal articles | 2020
    Dr Dorothy Ann Machalek
    Shilling H; Murray G; Brotherton JML; Hawkes D; Saville M; Sivertsen T; Chambers I; Roberts J; Farnsworth A; Garland SM; Hocking JS; Kaldor J; Guy R; Atchison S; Costa AM; Molano M; Machalek DA, 2020, 'Monitoring human papillomavirus prevalence among young Australian women undergoing routine chlamydia screening', Vaccine, vol. 38, pp. 1186 - 1193, http://dx.doi.org/10.1016/j.vaccine.2019.11.019
    Journal articles | 2020
    Dr Dorothy Ann Machalek
    Latimer RL; Shilling HS; Vodstrcil LA; MacHalek DA; Fairley CK; Chow EPF; Read TRH; Bradshaw CS, 2020, 'Prevalence of Mycoplasma genitalium by anatomical site in men who have sex with men: A systematic review and meta-analysis', Sexually Transmitted Infections, vol. 96, pp. 563 - 570, http://dx.doi.org/10.1136/sextrans-2019-054310
    Journal articles | 2020
    Dr Dorothy Ann Machalek
    Murray GL; Doyle M; Bodiyabadu K; Vodstrcil LA; Garland SM; Danielewski J; Machalek DA; McGuinness C; Plummer EL; de Petra V; Williamson DA; Bradshaw CS, 2020, 'Evaluation of ResistancePlus MG FleXible, a 'near-patient' test for the detection of Mycoplasma genitalium and macrolide resistance mutations, using freshly collected clinical samples', Journal of Medical Microbiology, vol. 70, http://dx.doi.org/10.1099/JMM.0.001271
    Journal articles | 2020
    Dr Dorothy Ann Machalek
    Roberts JM; Poynten IM; Molano M; Machalek DA; Hillman RJ; Guzman P; Jin F; Templeton DJ; Fairley CK; Law C; Garland SM; Grulich AE; Cornall AM, 2020, 'Human papillomavirus genotypes in anal high-grade squamous intraepithelial lesion (HSIL): Anal intraepithelial neoplasia grades 2 (AIN2) and 3 (AIN3) are different', Cancer Epidemiology Biomarkers and Prevention, vol. 29, pp. 2078 - 2083, http://dx.doi.org/10.1158/1055-9965.EPI-20-0664
    Journal articles | 2020
    Dr Dorothy Ann Machalek
    Khawar L; Machalek DA; Regan DG; Donovan B; McGregor S; Guy RJ, 2020, 'Defining elimination of genital warts—a modified delphi study', Vaccines, vol. 8, pp. 1 - 17, http://dx.doi.org/10.3390/vaccines8020316
    Journal articles | 2020
    Dr Dorothy Ann Machalek
    Murray GL; Bodiyabadu K; Danielewski J; Garland SM; MacHalek DA; Fairley CK; Jensen JS; Williamson DA; Tan LY; Mokany E; Durukan D; Bradshaw CS, 2020, 'Moxifloxacin and Sitafloxacin Treatment Failure in Mycoplasma genitalium Infection: Association with parC Mutation G248T (S83I) and Concurrent gyrA Mutations', Journal of Infectious Diseases, vol. 221, pp. 1017 - 1024, http://dx.doi.org/10.1093/infdis/jiz550
    Journal articles | 2020
    Dr Dorothy Ann Machalek
    Murray GL; Danielewski J; Bradshaw CS; Williamson DA; Birnie J; Su JP; De Petra V; Tan LY; Wee R; MacHalek DA; Read TRH; Garland SM, 2020, 'Performance of the ResistancePlus MG diagnostic test for Mycoplasma genitalium using samples collected with Hologic Aptima Specimen Collection kits', Journal of Medical Microbiology, vol. 69, pp. 244 - 248, http://dx.doi.org/10.1099/jmm.0.001140
    Journal articles | 2020
    Dr Dorothy Ann Machalek
    Farnsworth A; Roberts JM; Garland SM; Crescini J; Kaldor JM; Machalek DA, 2020, 'Detection of high-grade cervical disease among women referred directly to colposcopy after a positive HPV screening test varies with age and cytology findings', International Journal of Cancer, vol. 147, pp. 3068 - 3074, http://dx.doi.org/10.1002/ijc.33128
    Journal articles | 2019
    Dr Dorothy Ann Machalek
    Drolet M; Bénard É; Pérez N; Brisson M; Ali H; Boily MC; Baldo V; Brassard P; Brotherton JML; Callander D; Checchi M; Chow EPF; Cocchio S; Dalianis T; Deeks SL; Dehlendorff C; Donovan B; Fairley CK; Flagg EW; Gargano JW; Garland SM; Grün N; Hansen BT; Harrison C; Herweijer E; Imburgia TM; Johnson AM; Kahn JA; Kavanagh K; Kjaer SK; Kliewer EV; Liu B; Machalek DA; Markowitz L; Mesher D; Munk C; Niccolai L; Nygård M; Ogilvie G; Oliphant J; Pollock KG; Purriños-Hermida MJ; Smith MA; Steben M; Söderlund-Strand A; Sonnenberg P; Sparen P; Tanton C; Wheeler CM; Woestenberg PJ; Yu BN, 2019, 'Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis', The Lancet, vol. 394, pp. 497 - 509, http://dx.doi.org/10.1016/S0140-6736(19)30298-3
    Journal articles | 2019
    Dr Dorothy Ann Machalek
    Chow EPF; Tabrizi SN; Fairley CK; Wigan R; Machalek DA; Regan DG; Hocking JS; Garland SM; Cornall AM; Atchison S; Bradshaw CS; McNulty A; Owen L; Marshall L; Russell DB; Kaldor JM; Chen MY, 2019, 'Prevalence of human papillomavirus in teenage heterosexual males following the implementation of female and male school-based vaccination in Australia: 2014–2017', Vaccine, vol. 37, pp. 6907 - 6914, http://dx.doi.org/10.1016/j.vaccine.2019.09.052
    Journal articles | 2019
    Dr Dorothy Ann Machalek
    Murray GL; Danielewski J; Bodiyabadu K; Machalek DA; Bradshaw CS; Costa AM; Birnie J; Garland SM, 2019, 'Analysis of infection loads in Mycoplasma genitalium clinical specimens by use of a commercial diagnostic test', Journal of Clinical Microbiology, vol. 57, http://dx.doi.org/10.1128/JCM.00344-19
    Journal articles | 2019
    Dr Dorothy Ann Machalek
    Machalek DA; Roberts JM; Garland SM; Thurloe J; Richards A; Chambers I; Sivertsen T; Farnsworth A, 2019, 'Routine cervical screening by primary HPV testing: early findings in the renewed National Cervical Screening Program', Medical Journal of Australia, vol. 211, pp. 113 - 119, http://dx.doi.org/10.5694/mja2.50223
    Journal articles | 2019
    Dr Dorothy Ann Machalek
    Murray GL; Su JP; Birnie J; Danielewski J; Machalek DA; Bradshaw CS; Read TRH; Costa AM; Garland SM, 2019, 'The impact of sample storage on molecular-based detection of Mycoplasma genitalium', Journal of Applied Microbiology, vol. 127, pp. 1219 - 1223, http://dx.doi.org/10.1111/jam.14359
    Journal articles | 2019
    Dr Dorothy Ann Machalek
    Brotherton JM; Hawkes D; Sultana F; Malloy MJ; Machalek DA; Smith MA; Garland SM; Saville M, 2019, 'Age-specific HPV prevalence among 116,052 women in Australia's renewed cervical screening program: A new tool for monitoring vaccine impact', Vaccine, vol. 37, pp. 412 - 416, http://dx.doi.org/10.1016/j.vaccine.2018.11.075
    Journal articles | 2018
    Dr Dorothy Ann Machalek
    Machalek DA; Garland SM; Brotherton JML; Bateson D; McNamee K; Stewart M; Rachel Skinner S; Liu B; Cornall AM; Kaldor JM; Tabrizi SN, 2018, 'Very Low Prevalence of Vaccine Human Papillomavirus Types among 18- to 35-Year Old Australian Women 9 Years Following Implementation of Vaccination', Journal of Infectious Diseases, vol. 217, pp. 1590 - 1600, http://dx.doi.org/10.1093/infdis/jiy075
    Journal articles | 2018
    Dr Dorothy Ann Machalek
    Pattanasri M; Elder K; Nickson C; Cooke S; Machalek D; Rose A; Mou A; Collins JP; Park A; De Boer R; Phillips C; Pridmore V; Farrugia H; Mann GB, 2018, 'Uptake of adjuvant breast cancer treatments recommended by multi-disciplinary meetings', ANZ Journal of Surgery, vol. 88, pp. 745 - 750, http://dx.doi.org/10.1111/ans.14368
    Journal articles | 2018
    Dr Dorothy Ann Machalek
    Elder K; Nickson C; Pattanasri M; Cooke S; Machalek D; Rose A; Mou A; Collins JP; Park A; De Boer R; Phillips C; Pridmore V; Farrugia H; Bruce Mann G, 2018, 'Treatment Intensity Differences After Early-Stage Breast Cancer (ESBC) Diagnosis Depending on Participation in a Screening Program', Annals of Surgical Oncology, vol. 25, pp. 2563 - 2572, http://dx.doi.org/10.1245/s10434-018-6469-7
    Journal articles | 2018
    Dr Dorothy Ann Machalek
    Roberts JM; Molano M; Thurloe JK; Hillman RJ; Templeton DJ; Law C; Mary Poynten I; Jin F; Guzman P; Garland SM; Machalek DA; Grulich AE; Cornall AM, 2018, 'Correlation between HPV16 positivity on anal swab and biopsy-confirmed HSIL caused by HPV16 in the study of the prevention of anal cancer (SPANC)', Papillomavirus Research, vol. 5, pp. S13 - S13, http://dx.doi.org/10.1016/j.pvr.2018.07.031
    Journal articles | 2018
    Dr Dorothy Ann Machalek
    Roberts JM; Molano M; Thurloe JK; Hillman RJ; Templeton DJ; Law C; Mary Poynten I; Jin F; Guzman P; Garland SM; Machalek DA; Grulich AE; Cornall AM, 2018, 'Laser capture microdissection-identified HPV genotypes associated with intra-anal high and low-grade intraepithelial lesions', Papillomavirus Research, vol. 5, pp. S12 - S12, http://dx.doi.org/10.1016/j.pvr.2018.07.030
    Journal articles | 2017
    Dr Dorothy Ann Machalek
    Chow EPF; Machalek DA; Tabrizi SN; Danielewski JA; Fehler G; Bradshaw CS; Garland SM; Chen MY; Fairley CK, 2017, 'Quadrivalent vaccine-targeted human papillomavirus genotypes in heterosexual men after the Australian female human papillomavirus vaccination programme: a retrospective observational study', The Lancet Infectious Diseases, vol. 17, pp. 68 - 77, http://dx.doi.org/10.1016/S1473-3099(16)30116-5
    Journal articles | 2017
    Dr Dorothy Ann Machalek
    Jin F; Roberts JM; Grulich AE; Poynten IM; MacHalek DA; Cornall A; Phillips S; Ekman D; McDonald RL; Hillman RJ; Templeton DJ; Farnsworth A; Garland SM; Fairley CK; Tabrizi SN; Law C; Biro C; Richards A; Thurloe J; Adams M; McCaffery K; Howard K; Kelly P; Seeds D; Garcia M; Carr A; Feeney L; Gluyas R; Prestage G; Petoumenos K; Law M; Acraman B; McGrath P; Mellor R; Pezzopane P, 2017, 'The performance of human papillomavirus biomarkers in predicting anal high-grade squamous intraepithelial lesions in gay and bisexual men', AIDS, vol. 31, pp. 1303 - 1311, http://dx.doi.org/10.1097/QAD.0000000000001462
    Journal articles | 2017
    Dr Dorothy Ann Machalek
    Machalek DA; Chow EPF; Garland SM; Wigan R; Cornall AM; Fairley CK; Kaldor JM; Hocking JS; Williams H; McNulty A; Bell C; Marshall L; Ooi C; Chen MY; Tabrizi SN, 2017, 'Human Papillomavirus Prevalence in Unvaccinated Heterosexual Men after a National Female Vaccination Program', Journal of Infectious Diseases, vol. 215, pp. 202 - 208, http://dx.doi.org/10.1093/infdis/jiw530
    Journal articles | 2017
    Dr Dorothy Ann Machalek
    Poynten IM; Tabrizi SN; Jin F; Templeton DJ; Machalek DA; Cornall A; Phillips S; Fairley CK; Garland SM; Law C; Carr A; Hillman RJ; Grulich AE, 2017, 'Vaccine-preventable anal human papillomavirus in Australian gay and bisexual men', Papillomavirus Research, vol. 3, pp. 80 - 84, http://dx.doi.org/10.1016/j.pvr.2017.02.003
    Journal articles | 2017
    Dr Dorothy Ann Machalek
    Templeton DJ; Roberts JM; Poynten IM; Law C; Hillman RJ; Farnsworth A; Fairley CK; Tabrizi SN; Garland SM; Grulich AE; Jin F; Acraman B; Carr A; Carroll S; Cooper D; Cornall A; Crampton L; Fairley K; Feeney L; Fraissard E; Howard K; Law M; MacHalek D; McCaffery K; McGrath P; Mellor R; Norris R; O'Dwyer M; Pendlebury S; Petoumenos K; Phillips S; Prestage G; Richards A; Schema L; Seeds D; Segelov E; Thurloe J; Tong W; Varma R, 2017, 'Prevalence and predictors of unsatisfactory anal cytology tests in a cohort of gay and bisexual men in Sydney, Australia: Baseline findings from the Study of the Prevention of Anal Cancer (SPANC)', European Journal of Cancer Prevention, vol. 26, pp. 212 - 216, http://dx.doi.org/10.1097/CEJ.0000000000000321
    Journal articles | 2017
    Dr Dorothy Ann Machalek
    Cornall AM; Poljak M; Garland SM; Phillips S; Machalek DA; Tan JH; Quinn MA; Tabrizi SN, 2017, 'HPV genotype-specific concordance between EuroArray HPV, Anyplex II HPV28 and Linear Array HPV Genotyping test in Australian cervical samples', Papillomavirus Research, vol. 4, pp. 79 - 84, http://dx.doi.org/10.1016/j.pvr.2017.10.002
    Journal articles | 2017
    Dr Dorothy Ann Machalek
    Das R; Machalek DA; Molesworth EG; Garland SM, 2017, 'Using Facebook to recruit young Australian men into a cross-sectional human papillomavirus study', Journal of Medical Internet Research, vol. 19, http://dx.doi.org/10.2196/jmir.8739
    Journal articles | 2017
    Dr Dorothy Ann Machalek
    Cornall AM; Poljak M; Garland SM; Phillips S; Tan JH; Machalek DA; Quinn MA; Tabrizi SN, 2017, 'Anyplex II HPV28 detection and Anyplex II HPV HR detection assays are highly concordant with other commercial assays for detection of high-risk HPV genotypes in women with high grade cervical abnormalities', European Journal of Clinical Microbiology and Infectious Diseases, vol. 36, pp. 545 - 551, http://dx.doi.org/10.1007/s10096-016-2831-5
    Journal articles | 2017
    Dr Dorothy Ann Machalek
    MacHalek DA; Wark JD; Tabrizi SN; Hopper JL; Bui M; Dite GS; Cornall AM; Pitts M; Gertig D; Erbas B; Garland SM, 2017, 'Genetic and Environmental Factors in Invasive Cervical Cancer: Design and Methods of a Classical Twin Study', Twin Research and Human Genetics, vol. 20, pp. 10 - 18, http://dx.doi.org/10.1017/thg.2016.93
    Journal articles | 2017
    Dr Dorothy Ann Machalek
    Garland SM; Machalek DA, 2017, 'Maximizing the impact of human papillomavirus vaccination', Clinical Infectious Diseases, vol. 65, pp. 890 - 892, http://dx.doi.org/10.1093/cid/cix459
    Journal articles | 2016
    Dr Dorothy Ann Machalek
    Phillips S; Cornall AM; Machalek DA; Garland SM; Bateson D; Garefalakis M; Tabrizi SN, 2016, 'Comparison of the roche cobas® 4800 HPV assay to roche amplicor for detection of high-risk human papillomavirus', European Journal of Clinical Microbiology and Infectious Diseases, vol. 35, pp. 1305 - 1307, http://dx.doi.org/10.1007/s10096-016-2665-1
    Journal articles | 2016
    Dr Dorothy Ann Machalek
    Cornall AM; Poljak M; Garland SM; Phillips S; Machalek DA; Tan JH; Quinn MA; Tabrizi SN, 2016, 'EUROarray human papillomavirus (HPV) assay is highly concordant with other commercial assays for detection of high-risk HPV genotypes in women with high grade cervical abnormalities', European Journal of Clinical Microbiology and Infectious Diseases, vol. 35, pp. 1033 - 1036, http://dx.doi.org/10.1007/s10096-016-2634-8
    Journal articles | 2016
    Dr Dorothy Ann Machalek
    Roberts JM; Jin F; Thurloe JK; Ekman D; Adams MK; McDonald RL; Biro C; Poynten IM; Grulich AE; Farnsworth A; Aarnsworth R; Acraman B; Adams MK; Carr A; Carroll S; Cooper D; Cornall A; Crampton L; Fairley C; Farnsworth A; Feeney L; Garcia M; Garland S; Gluyas R; Hillman R; Howard K; Lawa F; Law C; Law M; Machalek D; McCaffery K; McDonald RL; McGrath P; Mellor R; Pendlebury S; Petoumenos K; Pezzopane P; Phillips S; Mary Poynten I; Prestage G; Richards A; Roberts JM; Seeds D; Segelov E; Tabrizi S; Templeton D; Tong W; Varma R, 2016, 'The value of a transformation zone component in anal cytology to detect HSIL', Cancer Cytopathology, vol. 124, pp. 596 - 601, http://dx.doi.org/10.1002/cncy.21730
    Journal articles | 2016
    Dr Dorothy Ann Machalek
    Machalek DA; Jin F; Poynten IM; Hillman RJ; Templeton DJ; Law C; Roberts JM; Tabrizi SN; Garland SM; Farnsworth A; Fairley CK; Grulich AE; Acraman B; Adams M; Carr A; Carroll S; Cooper D; Cornall A; Crampton L; Ekman D; Feeney L; Fraissard E; Howard K; Law M; McCaffery K; McDonald R; McGrath P; Mellor R; Norris R; O'Dwyer M; Pendlebury S; Petoumenos K; Phillips S; Prestage G; Richards A; Schema L; Seeds D; Segelov E; Thurloe J; Tong W; Varma R, 2016, 'Prevalence and risk factors associated with high-grade anal squamous intraepithelial lesions (HSIL)-AIN2 and HSIL-AIN3 in homosexual men', Papillomavirus Research, vol. 2, pp. 97 - 105, http://dx.doi.org/10.1016/j.pvr.2016.05.003
    Journal articles | 2016
    Dr Dorothy Ann Machalek
    Machalek DA; Poynten IM; Jin F; Hillman RJ; Templeton DJ; Law C; Roberts JM; Tabrizi SN; Garland SM; Farnsworth A; Fairley CK; Grulich AE; Acraman B; Adams M; Carr A; Carroll S; Cooper D; Cornall A; Crampton L; Ekman D; Fairley K; Feeney L; Fraissard E; Howard K; Law M; McCaffery K; McDonald R; McGrath P; Mellor R; Norris R; O'Dwyer M; Pendlebury S; Petoumenos K; Phillips S; Prestage G; Richards A; Schema L; Seeds D; Segelov E; Thurloe J; Tong W; Varma R, 2016, 'A composite cytology-histology endpoint allows a more accurate estimate of anal high-grade squamous intraepithelial lesion prevalence', Cancer Epidemiology Biomarkers and Prevention, vol. 25, pp. 1134 - 1143, http://dx.doi.org/10.1158/1055-9965.EPI-15-1106
    Journal articles | 2016
    Dr Dorothy Ann Machalek
    Poynten IM; Machalek D; Templeton D; Jin F; Hillman R; Zablotzska I; Prestage G; Holt M; Grulich A, 2016, 'Comparison of age-specific patterns of sexual behaviour and anal HPV prevalence in homosexual men with patterns in women', Sexually Transmitted Infections, vol. 92, pp. 228 - 231, http://dx.doi.org/10.1136/sextrans-2015-052032
    Journal articles | 2016
    Dr Dorothy Ann Machalek
    Tung ILY; Machalek DA; Garland SM, 2016, 'Attitudes, knowledge and factors associated with Human Papillomavirus (HPV) vaccine uptake in adolescent girls and young women in Victoria, Australia', PLoS ONE, vol. 11, http://dx.doi.org/10.1371/journal.pone.0161846
    Journal articles | 2016
    Dr Dorothy Ann Machalek
    Chow E; Machalek D; Tabrizi S; Danielewski J; Fehler G; Bradshaw C; Garland S; Chen M; Fairley C; Walker S, 2016, 'O027 Rapid fall in quadrivalent vaccine targeted human papillomavirus genotypes in heterosexual men following the Australian female HPV vaccination programme: an observational study from 2004 to 2015', Sexually Transmitted Infections, vol. 92, pp. A10.2 - A11, http://dx.doi.org/10.1136/sextrans-2016-052718.26
    Journal articles | 2016
    Dr Dorothy Ann Machalek
    Hocking JS; Vaughan C; Lau A; MacHelak DA; Graham S, 2016, 'Reducing the burden of sexually transmissible infections in Papua New Guinea requires strengthening of clinical services and engaging men', Sexual Health, vol. 13, pp. 401 - 403, http://dx.doi.org/10.1071/SH16058
    Journal articles | 2015
    Dr Dorothy Ann Machalek
    Garland SM; Molesworth EG; Machalek DA; Cornall AM; Tabrizi SN, 2015, 'How to best measure the effectiveness of male human papillomavirus vaccine programmes?', Clinical Microbiology and Infection, vol. 21, pp. 834 - 841, http://dx.doi.org/10.1016/j.cmi.2015.05.038
    Journal articles | 2015
    Dr Dorothy Ann Machalek
    Cornall AM; Roberts JM; Molano M; Machalek DA; Phillips S; Hillman RJ; Grulich AE; Jin F; Poynten IM; Templeton DJ; Garland SM; Tabrizi SN, 2015, 'BMJ open: Laser capture microdissection as a tool to evaluate human papillomavirus genotyping and methylation as biomarkers of persistence and progression of anal lesions', BMJ Open, vol. 5, http://dx.doi.org/10.1136/bmjopen-2015-008439
    Journal articles | 2015
    Dr Dorothy Ann Machalek
    Tabrizi SN; Costa AM; Marceglia A; Machalek DA; Bradshaw CS; Chen M; Fairley CK; Garland SM, 2015, 'P07.01 Mycoplasma genitaliumtesting pattern and infection rates over a six-year period in melbourne, australia', Sexually Transmitted Infections, vol. 91, pp. A120.2 - A121, http://dx.doi.org/10.1136/sextrans-2015-052270.317
    Journal articles | 2013
    Dr Dorothy Ann Machalek
    Machalek DA; Grulich AE; Hillman RJ; Jin F; Templeton DJ; Tabrizi SN; Garland SM; Prestage G; McCaffery K; Howard K; Tong W; Fairley CK; Roberts J; Farnsworth A; Poynten IM, 2013, 'The Study of the Prevention of Anal Cancer (SPANC): Design and methods of a three-year prospective cohort study', BMC Public Health, vol. 13, http://dx.doi.org/10.1186/1471-2458-13-946
    Journal articles | 2012
    Dr Dorothy Ann Machalek
    Grulich AE; Poynten IM; MacHalek DA; Jin F; Templeton DJ; Hillman RJ, 2012, 'The epidemiology of anal cancer', Sexual Health, vol. 9, pp. 504 - 508, http://dx.doi.org/10.1071/SH12070
    Journal articles | 2012
    Dr Dorothy Ann Machalek
    Machalek DA; Grulich AE; Jin F; Templeton DJ; Poynton IM, 2012, 'The epidemiology and natural history of anal human papillomavirus infection in men who have sex with men', Sexual Health, vol. 9, pp. 527 - 537, http://dx.doi.org/10.1071/SH12043
    Journal articles | 2012
    Dr Dorothy Ann Machalek
    Machalek DA; Poynten IM; Jin F; Fairley CK; Farnsworth A; Garland S; Hillman R; Petoumenos K; Roberts J; Tabrizi S; Templeton DJ; Grulich AE, 2012, 'Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: A systematic review and meta-analysis', Lancet Oncology, vol. 13, pp. 487 - 500, http://dx.doi.org/10.1016/S1470-2045(12)70080-3
    Journal articles | 2012
    Dr Dorothy Ann Machalek
    Grulich AE; Machalek DA; Poynton IM; Jin F; Fairley CK; Tabrizi S; Garland S; Templeton DJ; Hillman R, 2012, 'Anal cancer screening - Authors' reply', Lancet Oncology, vol. 13, pp. E280, http://dx.doi.org/10.1016/S1470-2045(12)70272-3
    Journal articles | 2012
    Dr Dorothy Ann Machalek
    Grulich AE; Machalek DA; Poynten IM; Jin F; Fairley CK; Tabrizi SN; Garland SM; Templeton DJ; Hillman RJ, 2012, 'Anal cancer screening Reply', LANCET ONCOLOGY, vol. 13, pp. E280 - E280, http://dx.doi.org/10.1016/S1470-2045(12)70272-3
    Journal articles | 2011
    Dr Dorothy Ann Machalek
    O'Toole S; Machalek DA; Shearer R; Millar E; Nair R; Schofield PR; McLeod D; Cooper CE; Mcneil CM; Mcfarland A; Nguyen A; Ormandy CJ; Qiu M; Rabinovich B; Martelotto L; Vu D; Hannigan GE; Musgrove EA; Christ DU; Sutherland RL; Watkins DJ; Swarbrick A, 2011, 'Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer', Cancer research, vol. 71, pp. 4002 - 4014, http://dx.doi.org/10.1158/0008-5472.CAN-10-3738
    Journal articles | 2010
    Dr Dorothy Ann Machalek
    Molano M; Tabrizi SN; Garland SM; Roberts JM; MacHalek DA; Phillips S; Chandler D; Hillman RJ; Grulich AE; Jin F; Poynten IM; Templeton DJ; Cornall AM; McCaffery K; Howard K; Farnsworth A; Fairley K; Prestage G; Carr A; Tong W; Law C; Acraman B; Crampton L; Feeney L; Fraissard E; Law M; McGrath P; Mellor R; Norris R; O'Dwyer M; Pendlebury S; Petoumenos K; Richards A; Schema L; Seeds D; Segelov E; Thurloe J; Varma R, 2010, 'CpG methylation analysis of hpv16 in laser capture microdissected archival tissue and whole tissue sections from high grade anal squamous intraepithelial lesions: A potential disease biomarker', PLoS ONE, vol. 11, http://dx.doi.org/10.1371/journal.pone.0160673
    Journal articles | 2010
    Dr Dorothy Ann Machalek
    Lawson VA; Lumicisi B; Welton J; Machalek D; Gouramanis K; Klemm HM; Stewart JD; Masters CL; Hoke DE; Collins SJ; Hill AF, 2010, 'Glycosaminoglycan sulphation affects the seeded misfolding of a mutant prion protein', PLoS ONE, vol. 5, http://dx.doi.org/10.1371/journal.pone.0012351
    Journal articles | 2010
    Dr Dorothy Ann Machalek
    Tanudji M; Machalek D; Arndt GM; Rivory L, 2010, 'Competition Between siRNA Duplexes: Impact of RNA-Induced Silencing Complex Loading Efficiency and Comparison Between Conventional-21 bp and Dicer-Substrate siRNAs', Oligonucleotides, vol. 20, pp. 27 - 32, http://dx.doi.org/10.1089/oli.2009.0195
    Journal articles | 2010
    Dr Dorothy Ann Machalek
    O'Toole SA; Machalek D; Shearer R; Millar EKA; Nair R; Martelotto L; McLeod D; Cooper C; Qiu MR; Sutherland RL; Watkins DN; Swarbrick A, 2010, 'Hedgehog Ligand Overexpression Predicts Poor Outcome in Breast Cancer and Is a Potential Therapeutic Target for Metastatic Disease', CANCER RESEARCH, vol. 70, http://dx.doi.org/10.1158/0008-5472.SABCS10-S6-8
    Journal articles | 2008
    Dr Dorothy Ann Machalek
    Lawson VA; Vella LJ; Stewart JD; Sharples RA; Klemm H; Machalek DM; Masters CL; Cappai R; Collins SJ; Hill AF, 2008, 'Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture', International Journal of Biochemistry and Cell Biology, vol. 40, pp. 2793 - 2801, http://dx.doi.org/10.1016/j.biocel.2008.05.024
  • Conference Papers | 2019
    Dr Dorothy Ann Machalek
    Machalek D; Tao Y; Shilling H; Jensen J; Unemo M; Murray G; Chow E; Low N; Garland S; Fairley C; Vodstrcil L; Hocking J; Zhang L; Bradshaw C, 2019, 'P601 Macrolide and fluoroquinolone resistance-associated mutations inmycoplasma genitalium:a systematic review and meta-analysis', in Poster Presentations, BMJ Publishing Group Ltd, presented at Abstracts for the STI & HIV World Congress (Joint Meeting of the 23rd ISSTDR and 20th IUSTI), July 14–17, 2019, Vancouver, Canada, http://dx.doi.org/10.1136/sextrans-2019-sti.669
    Conference Papers | 2019
    Dr Dorothy Ann Machalek
    Machalek D; Shilling H; Atchison S; Cornall A; Brotherton J; Bateson D; Mcnamee K; Hocking J; Kaldor J; Chen M; Fairley C; Chow E; Skinner SR; Murray G; Molano M; Tabrizi S; Garland S, 2019, 'P822 Factors associated with oncogenic human papillomavirus prevalence among australian women following vaccine introduction', in Poster Presentations, BMJ Publishing Group Ltd, presented at Abstracts for the STI & HIV World Congress (Joint Meeting of the 23rd ISSTDR and 20th IUSTI), July 14–17, 2019, Vancouver, Canada, http://dx.doi.org/10.1136/sextrans-2019-sti.867
    Conference Papers | 2019
    Dr Dorothy Ann Machalek
    Chow E; Tabrizi S; Fairley C; Wigan R; Regan D; Hocking J; Garland S; Brotherton J; Bradshaw C; Cornall A; McNulty A; Atchison S; Machalek D; Owen L; Marshall L; Russell D; Chen M, 2019, 'PREVALENCE OF HPV IN TEENAGE HETEROSEXUAL MALES AFTER THE INTRODUCTION OF THE GENDER-NEUTRAL VACCINATION PROGRAM IN AUSTRALIA', in SEXUALLY TRANSMITTED INFECTIONS, BMJ PUBLISHING GROUP, pp. A344 - A344, http://dx.doi.org/10.1136/sextrans-2019-sti.864
    Conference Papers | 2019
    Dr Dorothy Ann Machalek
    Chow E; Tabrizi S; Fairley C; Wigan R; Cornall A; Atchison S; Machalek D; Hocking J; Bradshaw C; Garland S; Chen M, 2019, 'P501 Low prevalence of high-risk anal HPV in young gay and bisexual males after the universal HPV vaccination program in australia', in Poster Presentations, BMJ Publishing Group Ltd, presented at Abstracts for the STI & HIV World Congress (Joint Meeting of the 23rd ISSTDR and 20th IUSTI), July 14–17, 2019, Vancouver, Canada, http://dx.doi.org/10.1136/sextrans-2019-sti.582
    Conference Papers | 2019
    Dr Dorothy Ann Machalek
    Murray G; Bradshaw C; Bodiyabadu K; Danielewski J; Birnie J; Tan L; Mokany E; Read T; Machalek D; Fairley C; Garland S, 2019, 'O04.4 Mycoplasma genitalium parC and gyrAmutations associated with moxifloxacin and sitafloxacin treatment failure', in Oral Presentations, BMJ Publishing Group Ltd, presented at Abstracts for the STI & HIV World Congress (Joint Meeting of the 23rd ISSTDR and 20th IUSTI), July 14–17, 2019, Vancouver, Canada, http://dx.doi.org/10.1136/sextrans-2019-sti.125
    Conference Papers | 2019
    Dr Dorothy Ann Machalek
    Latimer R; Shilling H; Vodstrcil L; Machalek D; Fairley C; Read T; Chow E; Bradshaw C, 2019, 'P525 Prevalence ofMycoplasma genitaliumby anatomical site in men who have sex with men: a systematic review and meta-analysis', in Poster Presentations, BMJ Publishing Group Ltd, presented at Abstracts for the STI & HIV World Congress (Joint Meeting of the 23rd ISSTDR and 20th IUSTI), July 14–17, 2019, Vancouver, Canada, http://dx.doi.org/10.1136/sextrans-2019-sti.603
    Conference Papers | 2018
    Dr Dorothy Ann Machalek
    Elder KJ; Nickson C; Cooke S; Machalek D; Rose A; Mou A; Collins JP; Park A; De Boer R; Phillips C; Pridmore V; Farrugia H; Mann GB, 2018, 'Abstract PD2-13: Benefits to breast screening beyond mortality reduction', in Poster Discussion Abstracts, American Association for Cancer Research, presented at Abstracts: 2017 San Antonio Breast Cancer Symposium; December 5-9, 2017; San Antonio, Texas, http://dx.doi.org/10.1158/1538-7445.sabcs17-pd2-13
    Conference Papers | 2015
    Dr Dorothy Ann Machalek
    Elder KJ; Cooke S; Machalek D; Rose A; Mou A; Collins JP; Nickson C; Park A; Mann B, 2015, 'Treatment intensity differences in screen-detected and community-detected early stage breast cancer (ESBC)', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, Chicago, IL, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Clinical Science Symposium on Predicting and Improving Adverse Outcomes in Older Adults with Cancer, Chicago, IL, 29 May 2015 - 02 June 2015, http://dx.doi.org/10.1200/jco.2015.33.15_suppl.1579
    Conference Papers | 2005
    Dr Dorothy Ann Machalek
    Lawson VA; Stewart JD; Machalek DA; Collins SJ; Masters CL; Hill AF, 2005, 'Identification of host factors that affect the formation of the protease resistant form of the prion protein', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL PUBLISHING, INC, Innsbruck, AUSTRIA, pp. 146 - 146, presented at 20th Biennial Meeting of the International-Society-for-Neurochemistry/European-Society-for-Neurochemistry, Innsbruck, AUSTRIA, 21 August 2005 - 26 August 2005, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000231673401011&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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