Doctoral degree, Technical University of Munich (2019)
Medicine & Health
The Kirby Institute
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Eva is a Postdoctoral Fellow in the Infection Analytics Program at the Kirby Institute, UNSW.
She has a background in mathematical biology and received her doctoral degree in 2019 from the Technical University of Munich. In her research, she uses mathematical and quantitative methods to gain a better understanding of within host dynamics of infectious diseases (malaria and SARS-CoV-2) and immunity. In previous projects, she has, e.g., investigated the efficacy of passive antibody treatments against SARS-CoV-2, the risk of resistance against a novel antimalarial drug, the role of immunity in seasonal malaria infections, and different mechanisms of malaria relapses.
Eva has quantified the relationship between the neutralizing antibody level after treatment with monoclonal antibodies (mAbs) and efficacy for preventing COVID-19. This work provides a tool for the rapid prediction of mAb treatment efficacy with the emergence of new SARS-CoV-2 variants and led to her membership in the Australian National Clinical Evidence Taskforce.
Currently, Eva's research focuses on analyzing the risk of SARS-CoV-2 infections in immunosuppressed patients. Using statistical analysis and model fitting of published vaccine effectiveness data, she explores the effect of different conditions and treatments on vaccine effectiveness in immunosuppressed patients. Moreover, she investigates how assay-related differences impact the measured level of neutralization (a known correlate of protection for SARS-CoV-2).
Elias KM; Khan SR; Stadler E; Schlub TE; Cromer D; Polizzotto MN; Kent SJ; Turner T; Davenport MP; Khoury DS, 2024, 'Viral clearance as a surrogate of clinical efficacy for COVID-19 therapies in outpatients: a systematic review and meta-analysis', Lancet Microbe, 5, pp. e459 - e467, http://dx.doi.org/10.1016/S2666-5247(23)00398-1
Journal articles | 2023
Stadler E; Burgess MT; Schlub TE; Khan SR; Chai KL; McQuilten ZK; Wood EM; Polizzotto MN; Kent SJ; Cromer D; Davenport MP; Khoury DS, 2023, 'Monoclonal antibody levels and protection from COVID-19', Nature Communications, 14, pp. 4545, http://dx.doi.org/10.1038/s41467-023-40204-1
Journal articles | 2023
Stadler E; Chai KL; Schlub TE; Cromer D; Khan SR; Polizzotto MN; Kent SJ; Beecher C; White H; Turner T; Skoetz N; Estcourt L; McQuilten ZK; Wood EM; Khoury DS; Davenport MP, 2023, 'Determinants of passive antibody efficacy in SARS-CoV-2 infection: a systematic review and meta-analysis', Lancet Microbe, 4, pp. e883 - e892, http://dx.doi.org/10.1016/S2666-5247(23)00194-5
Journal articles | 2023
Stadler E; Cromer D; Ogunlade S; Ongoiba A; Doumbo S; Kayentao K; Traore B; Crompton PD; Portugal S; Davenport MP; Khoury DS, 2023, 'Evidence for exposure dependent carriage of malaria parasites across the dry season: modelling analysis of longitudinal data', Malaria Journal, 22, http://dx.doi.org/10.1186/s12936-023-04461-1
Journal articles | 2023
Stadler E; Maiga M; Friedrich L; Thathy V; Demarta-Gatsi C; Dara A; Sogore F; Striepen J; Oeuvray C; Djimdé AA; Lee MCS; Dembélé L; Fidock DA; Khoury DS; Spangenberg T, 2023, 'Author Correction: Propensity of selecting mutant parasites for the antimalarial drug cabamiquine (Nature Communications, (2023), 14, 1, (5205), 10.1038/s41467-023-40974-8)', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-41287-6
Journal articles | 2023
Stadler E; Maiga M; Friedrich L; Thathy V; Demarta-Gatsi C; Dara A; Sogore F; Striepen J; Oeuvray C; Djimdé AA; Lee MCS; Dembélé L; Fidock DA; Khoury DS; Spangenberg T, 2023, 'Propensity of selecting mutant parasites for the antimalarial drug cabamiquine', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-40974-8
Journal articles | 2022
Kent SJ; Khoury DS; Reynaldi A; Juno JA; Wheatley AK; Stadler E; John Wherry E; Triccas J; Sasson SC; Cromer D; Davenport MP, 2022, 'Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?', Nature Reviews Immunology, 22, pp. 387 - 397, http://dx.doi.org/10.1038/s41577-022-00716-1
Journal articles | 2022
Koutsakos M; Lee WS; Reynaldi A; Tan HX; Gare G; Kinsella P; Liew KC; Taiaroa G; Williamson DA; Kent HE; Stadler E; Cromer D; Khoury DS; Wheatley AK; Juno JA; Davenport MP; Kent SJ, 2022, 'The magnitude and timing of recalled immunity after breakthrough infection is shaped by SARS-CoV-2 variants', Immunity, 55, pp. 1316 - 1326.e4, http://dx.doi.org/10.1016/j.immuni.2022.05.018
Journal articles | 2022
Mehra S; Stadler E; Khoury D; McCaw JM; Flegg JA, 2022, 'Hypnozoite dynamics for Plasmodium vivax malaria: The epidemiological effects of radical cure', Journal of Theoretical Biology, 537, http://dx.doi.org/10.1016/j.jtbi.2022.111014
Spriewald S; Stadler E; Hense BA; Münch PC; McHardy AC; Weiss AS; Obeng N; Müller J; Stecher B, 2020, 'Evolutionary stabilization of cooperative toxin production through a bacterium-plasmid-phage interplay', Mbio, 11, pp. 1 - 18, http://dx.doi.org/10.1128/mBio.00912-20
Journal articles | 2020
Stadler E; Müller J, 2020, 'Analyzing plasmid segregation: Existence and stability of the eigensolution in a non-compact case', Discrete and Continuous Dynamical Systems Series B, 25, pp. 4127 - 4164, http://dx.doi.org/10.3934/dcdsb.2020090
Journal articles | 2019
Müller J; Spriewald S; Stecher B; Stadler E; Fuchs TM, 2019, 'Evolutionary Stability of Salmonella Competition with the Gut Microbiota: How the Environment Fosters Heterogeneity in Exploitative and Interference Competition', Journal of Molecular Biology, 431, pp. 4732 - 4748, http://dx.doi.org/10.1016/j.jmb.2019.06.027
Journal articles | 2019
Stadler E, 2019, 'Eigensolutions and spectral analysis of a model for vertical gene transfer of plasmids', Journal of Mathematical Biology, 78, pp. 1299 - 1330, http://dx.doi.org/10.1007/s00285-018-1310-2
Preprints | 2023
Elias K; Khan S; Stadler E; Schlub T; Cromer D; Polizzotto M; Kent S; Turner T; Davenport M; Khoury D, 2023, Viral clearance as a surrogate of clinical efficacy for COVID-19 therapies in outpatients: A systematic review and meta-analysis, http://dx.doi.org/10.1101/2023.06.18.23291566
Preprints | 2022
Stadler E; Burgess M; Schlub T; Chai KL; McQuilten Z; Wood E; Polizzotto M; Kent S; Cromer D; Davenport M; Khoury D, 2022, Monoclonal antibody levels and protection from COVID-19, http://dx.doi.org/10.1101/2022.11.22.22282199
Preprints | 2022
Stadler E; Chai KL; Schlub T; Cromer D; Polizzotto M; Kent S; Beecher C; White H; White H; Turner T; Skoetz N; Skoetz N; Estcourt L; McQuilten Z; Wood E; Khoury D; Davenport M, 2022, Determinants of passive antibody efficacy in SARS-CoV-2 infection, http://dx.doi.org/10.1101/2022.03.21.22272672
Preprints | 2022
Stadler E; Cromer D; Mehra S; Adekunle A; Flegg J; Anstey N; Watson J; Chu C; Mueller I; Robinson L; Schlub T; Davenport M; Khoury D, 2022, Risk of Plasmodium vivax recurrences follows a 30-70 rule and indicates relapse heterogeneity in the population, http://dx.doi.org/10.1101/2022.05.18.22275180
Preprints | 2022
Stadler E; Cromer D; Ogunlade S; Ongoiba A; Doumbo S; Kayentao K; Traore B; Crompton P; Portugal S; Davenport M; Khoury D, 2022, A role for super-spreaders in carrying malaria parasites across the months-long dry season, http://dx.doi.org/10.1101/2022.04.28.22274398
Preprints | 2021
Koutsakos M; Lee WS; Reynaldi A; Tan H-X; Gare G; Kinsella P; Liew KC; Williamson D; Kent H; Stadler E; Cromer D; Khoury D; Wheatley A; Juno J; Davenport M; Kent S, 2021, Dynamics of immune recall following SARS-CoV-2 vaccination or breakthrough infection, http://dx.doi.org/10.1101/2021.12.23.21268285
Preprints | 2021
Mehra S; Stadler E; Khoury D; McCaw JM; Flegg JA, 2021, Hypnozoite dynamics for Plasmodium vivax malaria: the epidemiological effects of radical cure, http://dx.doi.org/10.48550/arxiv.2107.00779
NHMRC Investigator Grants Emerging Leadership 1 (EL1): 01/01/2025 to 31/12/2029
