Dr Heloisa Helena   Milioli
Conjoint Lecturer

Dr Heloisa Helena Milioli

medicine-health
St Vincent's Clinical School

Dr Heloisa Helena Milioli completed her PhD from the University of Newcastle (UoN) in 2017 and pursued a postdoctoral training with A/Prof Elgene Lim at the Connie Johnson Breast Cancer Research Laboratory, Garvan Institute of Medical Research. She was awarded the Cancer Institute of NSW Early-Career Fellowship (2018 – 2020) to study the interplay between sex steroid hormone receptors in cancer, with particular emphasis on novel therapeutic strategies for endocrine-resistant breast cancers.

Phone
0422262707
Location
The Kinghorn Cancer Centre 370 Victoria St, Darlinghurst NSW 2010

Publications

  • Journal articles | 2021
    Dr Heloisa Helena Milioli
    Hickey TE; Selth LA; Chia KM; Laven-Law G; Milioli HH; Roden D; Jindal S; Hui M; Finlay-Schultz J; Ebrahimie E; Birrell SN; Stelloo S; Iggo R; Alexandrou S; Caldon CE; Abdel-Fatah TM; Ellis IO; Zwart W; Palmieri C; Sartorius CA; Swarbrick A; Lim E; Carroll JS; Tilley WD, 2021, 'The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer', Nature Medicine, vol. 27, pp. 310 - 320, http://dx.doi.org/10.1038/s41591-020-01168-7
    Journal articles | 2020
    Dr Heloisa Helena Milioli
    Heng B; Bilgin AA; Lovejoy DB; Tan VX; Milioli HH; Gluch L; Bustamante S; Sabaretnam T; Moscato P; Lim CK; Guillemin GJ, 2020, 'Differential kynurenine pathway metabolism in highly metastatic aggressive breast cancer subtypes: beyond IDO1-induced immunosuppression', Breast Cancer Research, vol. 22, http://dx.doi.org/10.1186/s13058-020-01351-1
    Journal articles | 2020
    Dr Heloisa Helena Milioli
    Milioli HH; Alexandrou S; Lim E; Caldon CE, 2020, 'Cyclin E1 and cyclin E2 in ER+ breast cancer: Prospects as biomarkers and therapeutic targets', Endocrine-Related Cancer, vol. 27, pp. R93 - R112, http://dx.doi.org/10.1530/ERC-19-0501
    Journal articles | 2020
    Dr Heloisa Helena Milioli
    Portman N; Milioli HH; Alexandrou S; Coulson R; Yong A; Fernandez KJ; Chia KM; Halilovic E; Segara D; Parker A; Haupt S; Haupt Y; Tilley WD; Swarbrick A; Caldon CE; Lim E, 2020, 'MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer', Breast Cancer Research, vol. 22, pp. 87, http://dx.doi.org/10.1186/s13058-020-01318-2
    Journal articles | 2019
    Dr Heloisa Helena Milioli
    Chia KM; Milioli H; Portman N; Laven-Law G; Coulson R; Yong A; Segara D; Parker A; Caldon CE; Deng N; Swarbrick A; Tilley WD; Hickey TE; Lim E, 2019, 'Non-canonical AR activity facilitates endocrine resistance in breast cancer', Endocrine-Related Cancer, vol. 26, pp. 251 - 264, http://dx.doi.org/10.1530/ERC-18-0333
    Journal articles | 2017
    Dr Heloisa Helena Milioli
    Milioli HH; Tishchenko I; Riveros C; Berretta R; Moscato P, 2017, 'Basal-like breast cancer: molecular profiles, clinical features and survival outcomes', BMC Medical Genomics, vol. 10, http://dx.doi.org/10.1186/s12920-017-0250-9
    Journal articles | 2016
    Dr Heloisa Helena Milioli
    Oliveira NCS; Gomig THB; Milioli HH; Cordeiro F; Costa GG; Urban CA; Lima RS; Cavalli IJ; Ribeiro EMSF, 2016, 'Comparative proteomic analysis of ductal and lobular invasive breast carcinoma', Genetics and Molecular Research, vol. 15, http://dx.doi.org/10.4238/gmr.15027701
    Journal articles | 2016
    Dr Heloisa Helena Milioli
    Tishchenko I; Milioli HH; Riveros C; Moscato P, 2016, 'Extensive transcriptomic and genomic analysis provides new insights about luminal breast cancers', PLoS ONE, vol. 11, http://dx.doi.org/10.1371/journal.pone.0158259
    Journal articles | 2016
    Dr Heloisa Helena Milioli
    Milioli HH; Vimieiro R; Tishchenko I; Riveros C; Berretta R; Moscato P, 2016, 'Iteratively refining breast cancer intrinsic subtypes in the METABRIC dataset', BioData Mining, vol. 9, http://dx.doi.org/10.1186/s13040-015-0078-9
    Journal articles | 2016
    Dr Heloisa Helena Milioli
    Milioli HH, 2016, 'Life as an early career researcher: Interview with Heloisa Helena Milioli', Future Science OA, vol. 2, http://dx.doi.org/10.4155/fsoa-2016-0033
    Journal articles | 2015
    Dr Heloisa Helena Milioli
    Milioli HH; Sousa KS; Kaviski R; Oliveira NCDS; De Andrade Urban C; De Lima RS; Cavalli IJ; De Souza Fonseca Ribeiro EM, 2015, 'Comparative proteomics of primary breast carcinomas and lymph node metastases outlining markers of tumor invasion', Cancer Genomics and Proteomics, vol. 12, pp. 89 - 101
    Journal articles | 2015
    Dr Heloisa Helena Milioli
    Milioli HH; Vimieiro R; Riveros C; Tishchenko I; Berretta R; Moscato P, 2015, 'The discovery of novel biomarkers improves breast cancer intrinsic subtype prediction and reconciles the labels in the METABRIC data set', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0129711
    Journal articles | 2015
    Dr Heloisa Helena Milioli
    Milioli HH; Tishchenko I; Riveros C; Berretta R; Moscato P, 2015, 'Molecular classification of basal-like breast cancer subtypes based on predictive survival markers', Annals of Oncology, vol. 26, pp. iii15, http://dx.doi.org/10.1093/annonc/mdv117.11
    Journal articles | 2015
    Dr Heloisa Helena Milioli
    Milioli HH; Tishchenko I; Riveros C; Sakoff J; Berretta R; Moscato P, 2015, 'Consensus on breast cancer cell lines classification for an effective and efficient clinical decision-making', Annals of Oncology, vol. 26, pp. iii31, http://dx.doi.org/10.1093/annonc/mdv121.08
  • Conference Papers | 2021
    Dr Heloisa Helena Milioli
    Portman N; Milioli H; Alexandrou S; Coulson R; Yong A; Fernandez K; Chia K; Halilovic E; Segara D; Parker A; Haupt S; Haupt Y; Tilley W; Swarbrick A; Caldon L; Lim E, 2021, 'Abstract PS18-17: Mdm2 inhibition synergises with endocrine therapy or cdk4/6 inhibition for the treatment of estrogen receptor-positive breast cancer', in Poster Session Abstracts, American Association for Cancer Research, presented at Abstracts: 2020 San Antonio Breast Cancer Virtual Symposium; December 8-11, 2020; San Antonio, Texas, http://dx.doi.org/10.1158/1538-7445.sabcs20-ps18-17
    Conference Abstracts | 2020
    Dr Heloisa Helena Milioli
    Hickey T; Selth L; Chia KM; Milioli HH; Laven-Law G; Roden D; Jindal S; Hui M; Ebrahimie E; Birrel SN; Stello S; Iggo R; Alexandrou S; Caldon L; Finlay-Shultz J; Abdel-Fatah TM; Ellis IO; Zwart W; Palmieri C; Sartorious CA; Swarbrick A; Lim E; Carrol JS; Tilley WD, 2020, 'The androgen receptor is a tumour suppressor in estrogen receptor positive breast cancer', in Journal of the Endocrine Society, Oxford University Press (OUP), presented at Endocrine Society Annual Meeting, http://dx.doi.org/10.1210/jendso/bvaa046.982
    Conference Presentations | 2019
    Dr Heloisa Helena Milioli
    Portman N; Milioli HH; Alexandrou S; Coulson R; Young A; Chia KM; Haup S; Haup Y; Caldon L; Lim E, 2019, 'The MDM2 inhibitor NVP-CGM097 synergises with fulvestrant and inhibits Estrogen Receptor positive breast cancer', presented at Hormone-Dependent Cancers (GRS), Newry, USA
    Conference Abstracts | 2019
    Dr Heloisa Helena Milioli
    Alexandrou S; Milioli HH; Portman N; Lee C; Fernandez K; Blake D; Lim E; Caldon L, 2019, 'S phase dysregulation occurs following resistance to CDK4/6 inhibition ER+ breast cancer', in Oncolabs, presented at 7th PacRim Breast & Prostate Cancer Meeting, http://dx.doi.org/10.1530/oncolabs.1.P001
    Conference Abstracts | 2019
    Dr Heloisa Helena Milioli
    Portman N; Milioli HH; Young A; Coulson R; Alexandrou S; Lam N; Haup S; Haup Y; Caldon L; Deng N; Lim E, 2019, 'Activation of p53 in combination with endocrine and CDK targeted therapies in ER+ breast cancer', in Oncolabs, presented at 7th PacRim Breast & Prostate Cancer Meeting, http://dx.doi.org/10.1530/oncolabs.1.P043
    Conference Abstracts | 2019
    Dr Heloisa Helena Milioli
    Lim E; Hickey TA; Selth LA; Chia KM; Milioli HH; Roden D; Laven-Law G; Jindal S; Hui M; Ebrahimie E; Birrell SN; Stelloo S; Caldon CE; Finlay-Schultz J; Abdel-Fatah TM; Ellis IO; Zwart W; Palmieri C; Sartorius CA; Swarbrick A; Carroll JS; Tilley WD, 2019, 'The androgen receptor is a tumour suppressor in estrogen receptor positive breast cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, San Antonio, TX, Vol. 80, presented at 42nd Annual San Antonio Breast Cancer Symposium, San Antonio, TX, 09 December 2019 - 14 December 2019, http://dx.doi.org/10.1158/1538-7445.SABCS19-GS2-03
    Conference Abstracts | 2019
    Dr Heloisa Helena Milioli
    Wahlroos S; Wilkinson A; Milioli H; Portman N; Gallego-Ortega D; Lim E, 2019, 'Concurrent exercise and chemotherapy in preclinical breast cancer models', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, San Antonio, TX, Vol. 80, presented at 42nd Annual San Antonio Breast Cancer Symposium, San Antonio, TX, 09 December 2019 - 14 December 2019, http://dx.doi.org/10.1158/1538-7445.SABCS19-P4-14-13
    Conference Abstracts | 2019
    Dr Heloisa Helena Milioli
    Stirzaker C; Chia KM; Portman N; Milioli HH; Clifton S; Achinger-Kawecka J; Nair S; Lim E; Clark S, 2019, 'DNA demethylation agents as a therapeutic approach in endocrine-resistant breast cancer', in Oncolabs, presented at 7th PacRim Breast & Prostate Cancer Meeting, http://dx.doi.org/10.1530/oncolabs.1.P049
    Conference Abstracts | 2019
    Dr Heloisa Helena Milioli
    Milioli HH; Chia KM; Portman N; Young A; Laven-Law G; Selth L; Tilley WD; Hickey T; Lim E, 2019, 'Androgen receptor activation in Endocrine-Resistant ER-positive breast cancer', in Oncolabs, presented at 7th PacRim Breast & Prostate Cancer Meeting, http://dx.doi.org/10.1530/oncolabs.1.P034
    Conference Abstracts | 2019
    Dr Heloisa Helena Milioli
    Chia KM; Milioli HH; Portman N; Laven-Law G; Coulson R; Young A; Segara D; Parker A; Caldon L; Deng N; Swarbrick A; Tilley W; Hickey T; Lim E, 2019, 'Targeting AR in endocrine-resistant breast cancer', in Oncolabs, presented at 7th PacRim Breast & Prostate Cancer Meeting, http://dx.doi.org/10.1530/oncolabs.1.P012
    Conference Abstracts | 2018
    Dr Heloisa Helena Milioli
    Chia KM; Milioli H; Portman N; Laven-Law G; Yong A; Swarbrick A; Caldon L; Tilley W; Hickey T; Lim E, 2018, 'Activation of AR inhibits growth of endocrine-resistant breast cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, San Antonio, TX, Vol. 79, presented at San Antonio Breast Cancer Symposium, San Antonio, TX, 04 December 2018 - 08 December 2018, http://dx.doi.org/10.1158/1538-7445.SABCS18-P6-20-04
    Conference Abstracts | 2018
    Dr Heloisa Helena Milioli
    Wahlroos S; Wilkinson A; Gallego-Ortega D; Febbraio M; Lim E, 2018, 'Concurrent exercise and chemotherapy in preclinical breast cancer models', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, San Antonio, TX, Vol. 79, presented at San Antonio Breast Cancer Symposium, San Antonio, TX, 04 December 2018 - 08 December 2018, http://dx.doi.org/10.1158/1538-7445.SABCS18-P6-21-05
    Conference Abstracts | 2016
    Dr Heloisa Helena Milioli
    Milioli HH; Sanhueza C; Berretta R; Moscato P, 2016, 'Breast Cancer Molecular Portraits of Intrinsic Subtypes and Integrative Clusters in the METABRIC Data Set', in Asia Pacific Journal of Clinical Oncology, Wiley, presented at Hunter Cancer Research Alliance Annual Symposium, http://dx.doi.org/10.1111/ajco.12618
    Conference Presentations | 2016
    Dr Heloisa Helena Milioli
    Milioli HH; Sanhueza C; Riveros C; Berretta R; Moscato P, 2016, 'Breast cancer molecular portraits of intrinsic subtypes and integrative clusters in the METABRIC data set', presented at 2nd World Congress on Controversies in Breast Cancer (CoBrCA), Barcelona, Spain
    Conference Presentations | 2016
    Dr Heloisa Helena Milioli
    Milioli HH; Tishchenko I; Riveros C; Berretta R; Moscato P, 2016, 'Basal-like breast cancers uncovered by genomic and transcriptomic profiles and patients' overall survival', presented at Sydney Cancer Conference, Sydney NSW, Australia
    Conference Presentations | 2016
    Dr Heloisa Helena Milioli
    Milioli HH; Riveros C; Vimieiro R; Berretta R; Moscato P, 2016, 'Pairwise biomarker combinations and predictive modelling for breast cancer intrinsic subtypes', presented at 18th EMBL PhD Symposium, Heidelberg, Germany
    Conference Abstracts | 2015
    Dr Heloisa Helena Milioli
    Milioli HH; Tishchencko I; Riveros C; Berretta R; Moscato P, 2015, 'Basal-like breast cancer subgroups uncovered by genomic and transcriptomic profiles and overall survival outcomes', in Asia Pacific Journal of Clinical Oncology, Wiley, presented at Hunter Cancer Research Alliance Annual Symposium, http://dx.doi.org/10.1111/ajco.12444
    Conference Papers | 2015
    Dr Heloisa Helena Milioli
    Milioli HH, 2015, 'The IMPAKT of breast cancer research: Fundamental science and applied medicine', in Future Science OA, http://dx.doi.org/10.4155/fso.15.69
    Conference Presentations | 2015
    Dr Heloisa Helena Milioli
    Milioli HH; Vimieiro R; Tishchenko I; Riveros C; Berretta R; Moscato P, 2015, 'Refining the breast cancer molecular subtypes in the METABRIC data set', presented at World Congress on Controversies in Breast Cancer (CoBRA), Melbourne VIC, Australia
    Conference Abstracts | 2015
    Dr Heloisa Helena Milioli
    Milioli HH; Tishchencko I; Riveros C; Sakoff J; Berretta R; Moscato P, 2015, 'Consensus on breast cancer cell lines classification for an effective and efficient clinical decision-making', in Annals of Oncology, Elsevier, presented at IMPAKT 2015 Breast Cancer Conference, http://dx.doi.org/10.1093/annonc/mdv121.08
    Conference Abstracts | 2015
    Dr Heloisa Helena Milioli
    Milioli HH; Tishchencko I; Riveros C; Berretta R; Moscato P, 2015, 'Molecular classification of basal-like breast cancer subtypes based on predictive survival markers', in Annals of Oncology, Elsevier, presented at IMPAKT 2015 Breast Cancer Conference, http://dx.doi.org/10.1093/annonc/mdv117.11
    Conference Abstracts | 2015
    Dr Heloisa Helena Milioli
    Tishchencko I; Milioli HH; Riveros C; Moscato P, 2015, 'How intrinsic are luminal breast cancer subtypes?', in Asia Pacific Journal of Clinical Oncology, Wiley, presented at Hunter Cancer Research Alliance Annual Symposium, http://dx.doi.org/10.1111/ajco.12444

Awards

Grants

Media