Dr Jackie Tan-Showyin
Senior Research Fellow (UNSW)

Dr Jackie Tan-Showyin

  • PhD in Optometry (University of New South Wales, 2006)
  • BOptom (Hons) (University of New South Wales, 1994)
  • Graduate Certificate in Ocular Therapeutics (University of New South Wales, 2015)
Medicine & Health
School of Optometry and Vision Science

Dr Jackie Tan-Showyin is Director of the Eye Research Group at the School of Optometry and Vision Science, UNSW Sydney, leading a passionate team conducting industry sponsored clinical trial research and investigator-initiated trials. Consistently delivering quality research and investing in building long term relationships with industry partners has resulted in collaboration with over 20 multinational industry partners. Her research focuses on dry eye, amongst the general population and in contact lens wearers, and contact lens design and performance. Her research has contributed to the development and subsequent approval of several new dry eye therapies and contacts lens designs over the course of her career. She also supervises PhD students and Masters of Optometry research projects, is a Fellow of the British Contact Lens Association, and a member of the Editorial Board for the journal Eye and Contact Lens.

Click here for more information on the Eye Research Group and Research Topics & Potential Supervisors

Phone
+61 2 9385 6551
Location
School of Optometry & Vision Science University of New South Wales Level 3, North Wing, Rupert Myers Building Gate 14, Barker St UNSW Sydney NSW 2052 Australia
  • Journal articles | 2022
    Tan J; Peguda R; Siddireddy JS; Briggs N; Stapleton F, 2022, 'Subjective Responses to Various Filling Solutions in the Posterior Fluid Reservoir of Miniscleral Lenses at Application', Eye & contact lens, vol. 48, pp. 73 - 77, http://dx.doi.org/10.1097/ICL.0000000000000855
    Journal articles | 2021
    Arshad M; Carnt N; Tan J; Stapleton F, 2021, 'Compliance behaviour change in contact lens wearers: a randomised controlled trial', Eye (Basingstoke), vol. 35, pp. 988 - 995, http://dx.doi.org/10.1038/s41433-020-1015-9
    Journal articles | 2021
    Arshad M; Carnt N; Tan J; Stapleton F, 2021, 'The Effect of Water Exposure on Contact Lens Storage Case Contamination in Soft Contact Lens Wearers', Optometry and Vision Science
    Journal articles | 2021
    Craig JP; Muntz A; Wang MTM; Luensmann D; Tan J; Trave Huarte S; Xue AL; Jones L; Willcox MDP; Wolffsohn JS, 2021, 'Developing evidence-based guidance for the treatment of dry eye disease with artificial tear supplements: A six-month multicentre, double-masked randomised controlled trial', Ocular Surface, vol. 20, pp. 62 - 69, http://dx.doi.org/10.1016/j.jtos.2020.12.006
    Journal articles | 2021
    Stapleton F; Bakkar M; Carnt N; Chalmers R; Vijay AK; Marasini S; Ng A; Tan J; Wagner H; Woods C; Wolffsohn JS, 2021, 'CLEAR - Contact lens complications', Contact Lens and Anterior Eye, vol. 44, pp. 330 - 367, http://dx.doi.org/10.1016/j.clae.2021.02.010
    Journal articles | 2021
    Tan J; Siddireddy JS; Wong K; Shen Q; Vijay AK; Stapleton F, 2021, 'Factors affecting microbial contamination on the back surface of worn soft contact lenses', Optometry and Vision Science, vol. 98, pp. 512 - 517, http://dx.doi.org/10.1097/OPX.0000000000001693
    Journal articles | 2020
    Aragona P; Benítez-Del-castillo JM; Coroneo MT; Mukherji S; Tan J; Vandewalle E; Vingrys A; Liu H; Carlisle-Wilcox C; Vehige J; Simmons PA, 2020, 'Safety and efficacy of a preservative-free artificial tear containing carboxymethylcellulose and hyaluronic acid for dry eye disease: A randomized, controlled, multicenter 3-month study', Clinical Ophthalmology, vol. 14, pp. 2951 - 2963, http://dx.doi.org/10.2147/OPTH.S256480
    Journal articles | 2020
    Downie LE; Hom MM; Berdy GJ; El-Harazi S; Verachtert A; Tan J; Liu H; Carlisle-Wilcox C; Simmons P; Vehige J, 2020, 'An artificial tear containing flaxseed oil for treating dry eye disease: A randomized controlled trial', Ocular Surface, vol. 18, pp. 148 - 157, http://dx.doi.org/10.1016/j.jtos.2019.11.004
    Journal articles | 2020
    Jerkins G; Greiner JV; Tong L; Tan J; Tauber J; Mearza A; Srinivasan S, 2020, 'A comparison of efficacy and safety of two lipid-based lubricant eye drops for the management of evaporative dry eye disease', Clinical Ophthalmology, vol. 14, pp. 1665 - 1673, http://dx.doi.org/10.2147/OPTH.S256351
    Journal articles | 2020
    Rayamajhee B; Subedi D; Won S; Kim J; Vijay A; Tan J; Henriquez FL; Willcox M; Carnt NA, 2020, 'Investigating domestic shower settings as a risk factor for acanthamoeba keratitis', Water (Switzerland), vol. 12, pp. 1 - 12, http://dx.doi.org/10.3390/w12123493
    Journal articles | 2020
    Siddireddy JS; Vijay AK; Tan J; Willcox M, 2020, 'Effect of Eyelid Treatments on Bacterial Load and Lipase Activity in Relation to Contact Lens Discomfort', Eye and Contact Lens, vol. 46, pp. 245 - 253, http://dx.doi.org/10.1097/ICL.0000000000000673
    Journal articles | 2020
    Tan J; Jia T; Liao R; Stapleton F, 2020, 'Effect of a formulated eye drop with Leptospermum spp honey on tear film properties', British Journal of Ophthalmology, vol. 104, pp. 1373 - 1377, http://dx.doi.org/10.1136/bjophthalmol-2019-315160
    Journal articles | 2019
    Arshad M; Carnt N; Tan J; Ekkeshis I; Stapleton F, 2019, 'Water Exposure and the Risk of Contact Lens-Related Disease', Cornea, vol. 38, pp. 791 - 797, http://dx.doi.org/10.1097/ICO.0000000000001898
    Journal articles | 2019
    Siddireddy JS; Tan J; Vijay AK; Willcox MDP, 2019, 'The Effect of Microblepharon Exfoliation on Clinical Correlates of Contact Lens Discomfort', Optometry and Vision Science, vol. 96, pp. 187 - 199, http://dx.doi.org/10.1097/OPX.0000000000001354
    Journal articles | 2019
    Wong K; Flanagan J; Jalbert I; Tan J, 2019, 'The effect of Blephadex™ Eyelid Wipes on Demodex mites, ocular microbiota, bacterial lipase and comfort: a pilot study', Contact Lens and Anterior Eye, vol. 42, pp. 652 - 657, http://dx.doi.org/10.1016/j.clae.2019.06.001
    Journal articles | 2018
    Asbell P; Vingrys AJ; Tan J; Ogundele A; Downie LE; Jerkins G; Shettle L, 2018, 'Clinical Outcomes of Fixed Versus As-Needed Use of Artificial Tears in Dry Eye Disease: A 6-Week, Observer-Masked Phase 4 Clinical Trial', Investigative Ophthalmology & Visual Science, vol. 59, pp. 2275 - 2280, http://dx.doi.org/10.1167/iovs.17-23733
    Journal articles | 2018
    Markoulli M; Sobbizadeh A; Tan J; Briggs N; Coroneo M, 2018, 'The Effect of Optive and Optive Advanced Artificial Tears on the Healthy Tear Film', Current Eye Research, vol. 43, pp. 588 - 594, http://dx.doi.org/10.1080/02713683.2018.1433860
    Journal articles | 2018
    Siddireddy JS; Tan J; Vijay AK; Willcox M, 2018, 'Predictive Potential of Eyelids and Tear Film in Determining Symptoms in Contact Lens Wearers', Optometry and Vision Science, vol. 95, pp. 1035 - 1045, http://dx.doi.org/10.1097/opx.0000000000001290
    Journal articles | 2018
    Siddireddy JS; Vijay AK; Tan J; Willcox M, 2018, 'The eyelids and tear film in contact lens discomfort', Contact Lens & Anterior Eye, vol. 41, pp. 144 - 153, http://dx.doi.org/10.1016/j.clae.2017.10.004
    Journal articles | 2018
    Stapleton F; Wong K; Willcox M; Tan J, 2018, 'The repeatability of tear film measurements in subjects with dry eye', Investigative Ophthalmology & Visual Science, vol. 59
    Journal articles | 2018
    Tan J; Datta A; Wong K; Willcox MDP; Vijay AK, 2018, 'Clinical outcomes and contact lens case contamination using a povidone-iodine disinfection system', Eye and Contact Lens, vol. 44, pp. S221 - S227, http://dx.doi.org/10.1097/ICL.0000000000000385
    Journal articles | 2018
    Tan J; Ho L; Wong K; La A; Lee S; Park S; Tran L; Stapleton F, 2018, 'The effects of a hydrating mask compared to traditional warm compresses on tear film properties in meibomian gland dysfunction', Contact Lens & Anterior Eye, vol. 41, pp. 83 - 87, http://dx.doi.org/10.1016/j.clae.2017.09.006
    Journal articles | 2017
    Stapleton F; Tan J, 2017, 'Impact of Contact Lens Material, Design, and Fitting on Discomfort', Eye & Contact Lens-Science and Clinical Practice, vol. 43, pp. 32 - 39, http://dx.doi.org/10.1097/icl.0000000000000318
    Journal articles | 2013
    Jansen ME; Kollbaum PS; Tan J; Meyer DM; Rickert ME, 2013, 'Vision performance with a contact lens designed to slow myopia progression', Optometry and Vision Science, vol. 90, pp. 205 - 214, http://dx.doi.org/10.1097/OPX.0b013e3182812205
    Journal articles | 2009
    Papas EB; Decenzo-Verbeten T; Fonn D; Holden BA; Kollbaum PS; Situ P; Tan J; Woods C, 2009, 'Utility of Short-Term Evaluation of Presbyopic Contact Lens Performance', Eye & Contact Lens-Science and Clinical Practice, vol. 35, pp. 144 - 148, http://dx.doi.org/10.1097/ICL.0b013e3181a20361
    Journal articles | 2007
    Tan J; Papas E; Carnt N; Jalbert I; Skotnitsky C; Shiobara M; Lum E; Holden B, 2007, 'Performance standards for toric soft contact lenses', Optometry and Vision Science, vol. 84, pp. 422 - 428, http://dx.doi.org/10.1097/OPX.0b013e318059063b
    Journal articles | 2003
    Tan J; Keay L; Jalbert I; Naduvilath TJ; Sweeney DF; Holden BA, 2003, 'Mucin balls with wear of conventional and silicone hydrogel contact lenses', Optometry and Vision Science, vol. 80, pp. 291 - 297, http://dx.doi.org/10.1097/00006324-200304000-00006
    Journal articles | 2000
    Tan J; Keay LJ; Sweeney DF, 2000, 'Mucin balls and high Dk soft contact lenses', Contact Lens Spectrum, pp. 42 - 44
  • Conference Abstracts | 2018
    Siddireddy JS; Vijay AK; Tan J; Willcox M, 2018, 'Do the saturation and fatty acid chain length of meibum and tear lipids determine symptoms in contact lens wearers?', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Honolulu, HI, Vol. 59, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu, HI, 29 April 2018 - 03 May 2018, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000442912505061&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2018
    Vijay AK; Tang A; Pham R; Tan J; Willcox MDP, 2018, 'Transmission of pathogenic bacteria to contact lenses from storage cases', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Honolulu, HI, Vol. 59, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu, HI, 29 April 2018 - 03 May 2018, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000442912505105&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2017
    Asbell PA; Vingrys AJ; Tan J; Shettle PL; McLaurin EB; Ogundele A; Downie LE; Jenkins G, 2017, 'Fixed versus pro-re-nata dosing of polyethylene glycol/propylene glycol-based artificial tears: A randomized clinical trial', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Baltimore, MD, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO) - Imaging in the Eye, Baltimore, MD, 06 May 2017 - 11 May 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000432170306405&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2015
    Coroneo MT; Aragona P; Benitez-del-Castillo J; Tan J; Vandewalle E; Vingrys AJ; Liu H; Simmons PA; Vehige JG; Chen R, 2015, 'A Controlled 3-Month Clinical Study to Evaluate the Safety and Efficacy of an Investigational Eye Drop Formulation in Subjects with Dry Eye Disease', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Denver, CO, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Denver, CO, 03 May 2015 - 07 May 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000362891103241&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Vijay AK; Tan J; Ho L; Penesyan A; Paulsen I; Willcox MDP, 2015, 'Microbiome of contact lens cases following corneal infiltrative events', in Investigative Ophthalmology & Visual Science, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Denver, CO, Vol. 56, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Denver, CO, 03 May 2015 - 07 May 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000362891102267&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2002
    Lum E; Tan J, 2002, 'Comparison of toric soft lens design', in Clinical and Experimental Ophthalmology, Blackwell Publishing Asia, Carlton, Victoria, Australia, pp. 21 - 21, presented at XXIXth International Congress of Ophthalmology, Darling Harbour, Sydney
    Conference Papers | 2002
    Tan J; Back A; Papas EB; O Hare N; Jalbert I; Skotnitsky C; Shiobara M; Holden BA, 2002, 'Performance standards for toric soft contact lenses', in Optometry and Vision Science, Lippincott Williams & Wilkins, Philadelphia, PA, pp. 131 - 131, presented at American Academy of Optometry (2002), San Diego, Californa, USA, 12 December 2002 - 15 December 2002
    Conference Abstracts | 2001
    Stern J; Skotnitsky C; O Hare N; Tan J; Wong PR; Sweeney DF; Holden BA, 2001, 'Comparison of the incidence of Contact Lens Papillary Conjuctivitis between six and thirty night high Dk soft extended wear schedules', in Investigative Ophthalmology and Visual Science, Association of Research Vision Ophthalmology Inc, Rockville, MD, USA, Vol. 42, pp. 597 - 597, presented at ARVO 2001: Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, 29 April 2001 - 04 May 2001, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000168392103174&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2001
    Tan J; Back A; Naduvilath T, 2001, 'Comparison of empirical versus diagnostic fitting of disposable soft toric lenses', in Optometry and Vision Science, Lippincott Williams & Wilkins, Philadelphia, PA, pp. 48 - 48, presented at American Academy of Optometry (2001), Philadelphia, Pennsylvania, 06 December 2001 - 10 December 2001
    Conference Papers | 2000
    Sweeney DF; Tan J; Keay LJ; Jalbert I; Holden BA, 2000, 'Tear microsphere (TMS) with high Dk lenses', in Contact Lens and Anterior Eye, Stockton Press, Basingstoke, UK, pp. 56 - 56, presented at British Contact Lens Association Annual Clinical Conference (BCLA 2000), Birmingham, England
    Conference Papers | 2000
    Tan J; Back A; O Hare N; Jalbert I; Skotnitsky C, 2000, 'Repeatability of soft toric lens location over time', in Optometry and Vision Science, Lippincott Williams & Wilkins, Philadelphia, PA, pp. 216 - 216, presented at American Academy of Optometry (2000), Orlando, Florida, USA
    Conference Papers | 2000
    Tan J; Keay LJ; Jalbert I; Sweeney DF; Holden BA, 2000, 'Mucin balls with high Dk lenses', in Australian and New Zealand Journal of Ophthalmology, Blackwell Science Asia, South Carlton, Australia, pp. 117 - 117, presented at Australasian Ophthalmic and Visual Sciences Meeting 2000, Sydney

  • Changes in corneal epithelial irregularity following treatment with artificial tears in a symptomatic dry eye population: $261,067
  • Comparison of the DNEye® Scanner 2 and the IOLMaster 700 for axial length measurement in children: $125,998
  • A randomised, placebo-controlled, double-masked, multicenter, dose-ranging study to evaluate the safety, and efficacy of UNR844 in subjects with presbyopia: ~$249,010
  • A 52 week randomised, single-masked, multicenter proof of concept study of binocular videogames versus patching for amblyopia in children 4-7 years of age with an open-label substudy of binocular videogames in children 8-12 years of age: ~$14,000
  • A Randomised, Double-Masked Vehicle-Controlled, Multiple Dose, Dose Escalation Study to Evaluate the Safety and Tolerability of EXN407 in subjects with Centre Involved Diabetic Macular Oedema secondary to Diabetes Mellitus: ~$6,050
  • Measurement of eye drop retention time using a fluorophotometer: $207,655
  • A randomised, double masked, cross-over clinical trial to compare the vision performance of spectacles prescribed to 0.05D versus 0.25D steps: $142,075
  • A Multicenter, Vehicle-controlled, Randomised Study to Evaluate the Safety, Tolerability and Pharmacodynamics of AZR-MD-001 in Patients with Meibomian Gland Dysfunction (MGD): $74,842
  • A single-centre, vehicle-controlled study to evaluate methods to enhance the safety and tolerability of AZR-MD-001 for meibomian gland dysfunction (MGD): $317,292
  • A double-masked, randomised study of topical pilocarpine administered by the AcuStream delivery system in subjects with age-related presbyopia: $72,355
  • Developing evidence-based guidance for the treatment of dry eye disease (DED) with Systane artificial tear supplements: $123,546
  • A single-center, vehicle-controlled study to evaluate the safety, tolerability and pharmacodynamics of AZR-MD-001 as adjunctive therapy to conventional therapeutic treatment for meibomian gland dysfunction (MGD) : $309,390
  • A phase 2, multicenter, randomised, double-masked, placebo-controlled study to evaluate the clinical safety and efficacy of OKG-0301 in the treatment of acute adenoviral conjunctivitis (RUBY): $9,185
  • The effect of Systane Complete versus saline on tear film properties in a symptomatic dry eye population: $156,753
  • The effect of Systane Complete and Systane Hydration on subjective comfort, vision and satisfaction with mini-scleral contact lens wear: $189,495
  • A Multicenter, Vehicle-controlled, Randomised Study to Evaluate the Safety, Tolerability, Systemic Pharmacokinetics, and Pharmacodynamics in MGD: $403,933
  • Microbial contamination rates on the back surface of soft contact lenses in short-term, randomised, contralateral non-dispensing studies: $164,502
  • Clinical evaluation following use of SYSTANE BALANCE in subjects with lipid-deficient dry eye: $79,780
  • A two comparator, controlled phase 3 study of OM3 Tear formulation versus OPTIVE ADVANCED Unit Dose: $465,040
  • The effects of dietary supplementation with a combination of flaxseed oil, borage oil and fish oil omega-3 fatty acids on ocular comfort including symptoms of dry eye: $127,980
  • Pilot study on the effect of daily disposable silicone hydrogel contact lenses on tear film: $189,822
  • The role of tear lipids in differentiating symptomatic and asymptomatic contact lens wearers – clinical study: $112,352
  • Clinical evaluation following use of SYSTANE ULTRA in the management of dry eye: $54,700
  • A multicentre, double-masked, randomised study to compare the safety and efficacy of 2 OM3 formulations with REFRESH OPTIVE ADVANCED unit dose for 3 months in patients with dry eye disease: $173,953
  • A 3 month dispensing study of First Care cleaning and disinfecting solution in daily wear frequent replacement soft contact lens wearers: $89,284
  • A multicentre, double-masked, randomised study to compare the safety and efficacy of an investigational eye drop formulation with OPTIVE unit-dose for 3 months in subjects with dry eye disease: $169,371

Research:

Director, Eye Research Group at the School of Optometry and Vision Science, UNSW Sydney.

Current research trials include:

  • Changes in corneal epithelial irregularity following treatment with artificial tears in a symptomatic dry eye population
  • Comparison of the DNEye Scanner 2 and the IOLMaster 700 for axial length measurement in children
  • A randomised, placebo-controlled, double-masked, multicenter, dose-ranging study to evaluate the safety and efficacy of UNR844 in subjects with presbyopia
  • A randomised, double-masked vehicle-controlled, multiple dose, dose escalation study to evaluate the safety and tolerability of EXN407 in subjects with centre involved diabetic macular oedema secondary to diabetes mellitus
  • Measurement of eye drop retention time using a fluorophotometer
  • A multicenter, vehicle-controlled, randomised study to evaluate the safety, tolerability, systemic pharmacokinetcis, and pharmacodynamics in meibomian gland dysfunction


Teaching:

Supervision of Post-graduate and Honours Optometry students at UNSW.

Current projects include:

  • Longitudinal changes in meibomian gland morphology
  • Effect of eyelid wipes with Manuka honey on ocular signs and symptoms
  • Effect of Optimel Manuka+ Dry Eye Drops with adjunctive treatment on signs and symptoms of dry eye
  • Automatic diagnosis of dry eye disease
  • Predict contact lens discomfort with meibomian gland images

OPTM8514 Research Project

  • Effect of eyelid wipes with Manuka honey on ocular signs and symptoms
  • Effect of Optimel Manuka+ Dry Eye Drops with adjunctive treatment on signs and symptoms of dry eye
  • Automatic diagnosis of dry eye disease
  • Predict contact lens discomfort with meibomian gland images