Associate Professor Jason Harper
Associate Professor

Associate Professor Jason Harper

B.Sc. Adelaide, B.Sc.(Hons) ANU, Ph.D. ANU

Science
School of Chemistry

 

For more details, please see my website - www.jasonbharper.com

Jason Harper was born in Adelaide, Australia, but spent his childhood in the wilds of the Northern Territory.  He returned to Adelaide for secondary schooling and carried out his undergraduate work at the University of Adelaide and the Australian National University, also receiving his Ph.D. (under the supervision of Prof. Christopher (Chris) Easton) from ANU as the Shell Australia Postgraduate Scholar.  After positions at the University of Cambridge (as an NHMRC C. J. Martin Postdoctoral Fellow with Prof. Anthony (Tony) Kirby) and the Open University, he was appointed to the University of New South Wales in 2002, where he is currently an Associate Professor.

His research interests fall broadly in the area of mechanistic and physical organic chemistry.  His contributions to these fields have been in the understanding of the mechanisms of organic processes and what affects such, particularly involving the solvent effects of ionic liquids, novel methods to follow reaction outcomes and acidity of carbon acids.  He has published more than 130 articles and book chapters, has a h-index >35 and has given more than 70 invited lectures around the world.  He is an editor for the journal Chemical Physics and co-editor (with Prof. Nick WIlliams) of the book series, Advances in Physical Organic Chemistry. Along with these positions, is a member of the editorial board of ChemPlusChem, has collated a Research Topic for Frontiers in Chemistry (Ionic Liquids: Properties and Applications, 2018-2019), and been guest editor for themed collections for the Royal Society of Chemistry (Organic and Biomolecular Chemistry/Physical Chemistry Chemical Physics, Non-traditional solvent effects on organic processes, 2020-2021) and the American Chemical Society (Journal of Organic Chemistry, Solvation effects in organic chemistry, 2021).

Jason has been heavily involved in conference organisation.  He was a member of the three-person organising committee for the 4th Asia-Pacific Conference on Ionic Liquids, held at Coogee Beach in 2014.  More recently, he was bid developer and co-Chair of the 23rd IUPAC Conference on Physical Organic Chemistry (ICPOC23) held at the University of New South Wales in 2016.  Along with IUPAC conference involvement, Jason is a member of the Subcommittee on Structural and Mechanistic Chemistry and a Titular Member of Division III (Organic Chemistry).

Outside of the professional sphere, Jason enjoys keeping up with a diverse range of activities, ranging from cycling long distances periodically (Melbourne's "Around the Bay" is a favourite, though he has ridden Launceston to Hobart ... the long way!) to Taiko and Onikenbai (traditional Japanese drumming and "demon sword dance").

The explicit details: Born 1974. Undergraduate work carried out at the University of Adelaide (B.Sc. 1995) and in The Faculties, Australian National University (B.Sc.(Hons) 1996). Shell Australia Postgraduate Scholar, Research School of Chemistry, Australian National University (Ph.D. 2000). C. J. Martin Postdoctoral Fellow, University Chemical Laboratory, Cambridge (2000-2002). Associate Lecturer, The Open University in East Anglia (2001). Appointed Lecturer (2002-2006) Senior Lecturer (2007-2015) and Associate Professor (2016-).  SSP at Boston College (2009). Associate Member IUPAC Division III (2018-2019), Titular Member IUPAC Division III (2020-).

 

Phone
X54692
Location
Room 223, Dalton Building
  • Book Chapters | 2022
    Schaffarczyk McHale KS; Harper J, 2022, 'Pyridines and their benzo derivatives: Structure', in Comprehensive Organometallic Chemistry IV, Elsevier, pp. 1 - 25, http://dx.doi.org/10.1016/B978-0-12-818655-8.00068-8
    Book Chapters | 2018
    Gilbert A; Haines RS; Harper JB, 2018, 'Selecting Ionic Liquids to Enhance and Control Reaction Outcomes', in Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, Elsevier, http://dx.doi.org/10.1016/b978-0-12-409547-2.14212-x
    Book Chapters | 2018
    Hawker RR; Harper JB, 2018, 'Chapter Two Organic Reaction Outcomes in Ionic Liquids', in , pp. 49 - 85, http://dx.doi.org/10.1016/bs.apoc.2018.09.001
    Book Chapters | 2017
    Harper JB; Haines RS; Keaveney ST, 2017, 'Reactions in Ionic Liquids', in Encyclopedia of Physical Organic Chemistry, Volume 2, Wiley
    Book Chapters | 2015
    Hawker RR; Haines RS; Harper JB, 2015, 'Variation of the cation of ionic liquids: the effects on their physicochemical properties and reaction outcome', in Attanasi OA; Noto R; Spinelli D (ed.), Targets in Heterocyclic Systems: Chemistry and Properties, Vol 18, SOC CHIMICA ITALIANA, pp. 141 - 213
    Book Chapters | 2011
    Butler BJ; Hook J; Harper J, 2011, ''Recent Advances in the NMR Spectroscopy of Chlorine, Bromine and Iodine'', in Webb G (ed.), Annual Reports on NMR Spectroscopy, Academic Press, pp. 63 - 82, http://dx.doi.org/10.1016/B978-0-08-097074-5.00002-5
    Book Chapters | 2011
    Butler BJ; Hook JM; Harper JB, 2011, 'Chapter 2 Recent Advances in the NMR Spectroscopy of Chlorine, Bromine and Iodine', in , pp. 63 - 82, http://dx.doi.org/10.1016/b978-0-08-097074-5.00002-5
    Book Chapters | 2008
    Harper JB, 2008, 'Pyridines and their benzo derivatives: Structure', in Black DS; Katrizky AR; Ramsden CA; Scriven EFV; Taylor RJK (ed.), Comprehensive Heterocyclic Chemistry: Six Membered Rings with One Heteroatom with Fused Carbbocyclic Derivatives, Elsevier, Oxford, pp. 1 - 38
    Book Chapters | 2006
    Easton CJ; Harper JB; Lincoln SF, 2006, 'A molecular reactor for the synthesis of indirubin and related compounds', in Meijer L; Guyard N; Skaltsounis L; Eisenbrand G (ed.), Indirubin, the red shade of indigo, Life in Progress Editions, Roscoff, France, pp. 127 - 134, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000238003000013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
  • Journal articles | 2022
    Barnett C; Harper JB; Cole ML, 2022, 'Correlating Electronic Properties of N-Heterocyclic Carbenes with Structure, and the Implications of Using Different Probes', ChemistrySelect, vol. 7, http://dx.doi.org/10.1002/slct.202104348
    Journal articles | 2022
    Burrows CJ; Harper JB; Sander W; Tantillo DJ, 2022, 'Solvation Effects in Organic Chemistry', Journal of Organic Chemistry, vol. 87, pp. 1599 - 1601, http://dx.doi.org/10.1021/acs.joc.1c03148
    Journal articles | 2022
    Coney MD; Morris DC; Gilbert A; Prescott SW; Haines RS; Harper JB, 2022, 'Effects of Ionic Liquids on the Nucleofugality of Chloride', Journal of Organic Chemistry, vol. 87, pp. 1767 - 1779, http://dx.doi.org/10.1021/acs.joc.1c02043
    Journal articles | 2022
    Wang JE; Gilbert A; Harper JB; Kim DJ, 2022, 'Understanding the Failure Mechanism of Rechargeable Aluminum Batteries: Metal Anode Perspective Through X-Ray Tomography', ADVANCED ENERGY AND SUSTAINABILITY RESEARCH, vol. 3, http://dx.doi.org/10.1002/aesr.202100164
    Journal articles | 2021
    Barnett C; Cole ML; Harper JB, 2021, 'A Dual NMR Probe Approach to Understanding the Electronic Properties of N ‐Heterocyclic Carbenes', Chemistry–Methods, vol. 1, pp. 374 - 381, http://dx.doi.org/10.1002/cmtd.202100043
    Journal articles | 2021
    Barnett C; Cole ML; Harper JB, 2021, 'Steric Properties of N-Heterocyclic Carbenes affect the Performance of Electronic Probes', European Journal of Inorganic Chemistry, vol. 2021, pp. 4954 - 4958, http://dx.doi.org/10.1002/ejic.202100796
    Journal articles | 2021
    Chen J; Kato J; Harper JB; Shao Y; Ho J, 2021, 'On the Accuracy of QM/MM Models: A Systematic Study of Intramolecular Proton Transfer Reactions of Amino Acids in Water', Journal of Physical Chemistry B, vol. 125, pp. 9304 - 9316, http://dx.doi.org/10.1021/acs.jpcb.1c04876
    Journal articles | 2021
    Gilbert A; Haines RS; Harper JB, 2021, 'The effects of using an ionic liquid as a solvent for a reaction that proceeds through a phenonium ion', Journal of Physical Organic Chemistry, vol. 34, http://dx.doi.org/10.1002/poc.4217
    Journal articles | 2021
    Greaves TL; Schaffarczyk McHale KS; Burkart-Radke RF; Harper JB; Le TC, 2021, 'Machine learning approaches to understand and predict rate constants for organic processes in mixtures containing ionic liquids', Physical Chemistry Chemical Physics, vol. 23, pp. 2742 - 2752, http://dx.doi.org/10.1039/d0cp04227g
    Journal articles | 2021
    Harper JB; Kirchner B; Pavez P; Welton T, 2021, 'Non-traditional solvent effects in organic reactions', Physical Chemistry Chemical Physics, vol. 23, pp. 26028 - 26029, http://dx.doi.org/10.1039/d1cp90187g
    Journal articles | 2021
    Morris DC; Prescott SW; Harper JB, 2021, 'Rapid relaxation NMR measurements to predict rate coefficients in ionic liquid mixtures. An examination of reaction outcome changes in a homologous series of ionic liquids', Physical Chemistry Chemical Physics, vol. 23, pp. 9878 - 9888, http://dx.doi.org/10.1039/d0cp06066f
    Journal articles | 2021
    Munavirov B; Black JJ; Shah FU; Leckner J; Rutland MW; Harper JB; Glavatskih S, 2021, 'The effect of anion architecture on the lubrication chemistry of phosphonium orthoborate ionic liquids', Scientific Reports, vol. 11, pp. 24021, http://dx.doi.org/10.1038/s41598-021-02763-5
    Journal articles | 2021
    Rohlmann P; Watanabe S; Shimpi MR; Leckner J; Rutland MW; Harper JB; Glavatskih S, 2021, 'Boundary lubricity of phosphonium bisoxalatoborate ionic liquids', Tribology International, vol. 161, pp. 107075 - 107075, http://dx.doi.org/10.1016/j.triboint.2021.107075
    Journal articles | 2021
    Sandler I; Harper JB; Ho J, 2021, 'Explanation of Substituent Effects on the Enolization of β-Diketones and β-Ketoesters', Journal of Chemical Education, vol. 98, pp. 1043 - 1048, http://dx.doi.org/10.1021/acs.jchemed.0c01076
    Journal articles | 2020
    Blake SAP; Palmer J; Björklund J; Harper JB; Turney CSM, 2020, 'Palaeoclimate potential of New Zealand Manoao colensoi (silver pine) tree rings using Blue-Intensity (BI)', Dendrochronologia, vol. 60, pp. 125664 - 125664, http://dx.doi.org/10.1016/j.dendro.2020.125664
    Journal articles | 2020
    Gilbert A; Haines RS; Harper JB, 2020, 'Controlling the reactions of 1-bromogalactose acetate in methanol using ionic liquids as co-solvents', Organic and Biomolecular Chemistry, vol. 18, pp. 5442 - 5452, http://dx.doi.org/10.1039/d0ob01198c
    Journal articles | 2020
    Konstandaras N; Dunn MH; Luis ET; Cole ML; Harper JB, 2020, 'The p: K a values of N-aryl imidazolinium salts, their higher homologues, and formamidinium salts in dimethyl sulfoxide', Organic and Biomolecular Chemistry, vol. 18, pp. 1910 - 1917, http://dx.doi.org/10.1039/d0ob00036a
    Journal articles | 2020
    Liu KTC; Haines RS; Harper JB, 2020, 'The effect of bisimidazolium-based ionic liquids on a bimolecular substitution process. Are two head(group)s better than one?', Organic and Biomolecular Chemistry, vol. 18, pp. 7388 - 7395, http://dx.doi.org/10.1039/d0ob01500h
    Journal articles | 2020
    Mallo N; Tron A; Andréasson J; Harper JB; Jacob LSD; McClenaghan ND; Jonusauskas G; Beves JE, 2020, 'Hydrogen-Bonding Donor-Acceptor Stenhouse Adducts', ChemPhotoChem, vol. 4, pp. 407 - 412, http://dx.doi.org/10.1002/cptc.201900295
    Journal articles | 2020
    Schindl A; Hawker RR; Schaffarczyk McHale KS; Liu KTC; Morris DC; Hsieh AY; Gilbert A; Prescott SW; Haines RS; Croft AK; Harper JB; Jäger CM, 2020, 'Controlling the outcome of SN2 reactions in ionic liquids: From rational data set design to predictive linear regression models', Physical Chemistry Chemical Physics, vol. 22, pp. 23009 - 23018, http://dx.doi.org/10.1039/d0cp04224b
    Journal articles | 2019
    Butler BJ; Harper JB, 2019, 'The effect of the structure of the anion of an ionic liquid on the rate of reaction at a phosphorus centre', Journal of Physical Organic Chemistry, vol. 32, http://dx.doi.org/10.1002/poc.3819
    Journal articles | 2019
    Clarke CJ; Maxwell-Hogg S; Smith EF; Hawker RR; Harper JB; Licence P, 2019, 'Resolving X-ray photoelectron spectra of ionic liquids with difference spectroscopy', Physical Chemistry Chemical Physics, vol. 21, pp. 114 - 123, http://dx.doi.org/10.1039/c8cp06701e
    Journal articles | 2019
    Gilbert A; Bucher G; Haines RS; Harper JB, 2019, 'Correlating ionic liquid solvent effects with solvent parameters for a reaction that proceeds through a xanthylium intermediate', Organic and Biomolecular Chemistry, vol. 17, pp. 9336 - 9342, http://dx.doi.org/10.1039/c9ob01807g
    Journal articles | 2019
    Gilbert A; Haines RS; Harper JB, 2019, 'Understanding the effects of ionic liquids on a unimolecular substitution process: Correlating solvent parameters with reaction outcome', Organic and Biomolecular Chemistry, vol. 17, pp. 675 - 682, http://dx.doi.org/10.1039/c8ob02460j
    Journal articles | 2019
    Konstandaras N; Dunn MH; Guerry MS; Barnett CD; Cole ML; Harper JB, 2019, 'The impact of cation structure upon the acidity of triazolium salts in dimethyl sulfoxide', Organic and Biomolecular Chemistry, vol. 18, pp. 66 - 75, http://dx.doi.org/10.1039/c9ob02258a
    Journal articles | 2019
    Schaffarczyk McHale KS; Haines RS; Harper JB, 2019, 'Investigating Variation of the Pnicogen Nucleophilic Heteroatom on Ionic Liquid Solvent Effects in Bimolecular Nucleophilic Substitution Processes', ChemPlusChem, vol. 84, pp. 534 - 539, http://dx.doi.org/10.1002/cplu.201900188
    Journal articles | 2019
    Schaffarczyk McHale KS; Haines RS; Harper JB, 2019, 'The Dependence of Ionic Liquid Solvent Effects on the Nucleophilic Heteroatom in SNAr Reactions. Highlighting the Potential for Control of Selectivity', ChemPlusChem, vol. 84, pp. 465 - 473, http://dx.doi.org/10.1002/cplu.201900173
    Journal articles | 2019
    Schaffarczyk McHale KS; Wong MJ; Evans AK; Gilbert A; Haines RS; Harper JB, 2019, 'Understanding the effects of solvate ionic liquids as solvents on substitution processes', Organic and Biomolecular Chemistry, vol. 17, pp. 9243 - 9250, http://dx.doi.org/10.1039/c9ob01753d
    Journal articles | 2019
    Zheng X; Harper J; Hope G; Mooney SD, 2019, 'A new preparation method for testate amoebae in minerogenic sediments', Mires and Peat, vol. 24, pp. 1 - 12, http://dx.doi.org/10.19189/MaP.2018.OMB.380
    Journal articles | 2018
    Abbott A; Abe H; Aldous L; Atkin R; Bendová M; Busato M; Canongia Lopes JN; Costa Gomes M; Cross B; Dietz C; Everts J; Firestone M; Gardas R; Gras M; Greaves T; Halstead S; Hardacre C; Harper J; Holbrey J; Jacquemin J; Jessop P; Macfarlane D; Maier F; Medhi H; Mezger M; Pádua A; Perkin S; Reid JESJ; Saha S; Slattery JM; Thomas ML; Tiwari S; Tsuzuki S; Uralcan B; Watanabe M; Wishart J; Youngs T, 2018, 'Phase behaviour and thermodynamics: General discussion', Faraday Discussions, vol. 206, pp. 113 - 139, http://dx.doi.org/10.1039/c7fd90091k
    Journal articles | 2018
    Black JJ; Dolan A; Harper JB; Aldous L, 2018, 'Kamlet-Taft solvent parameters, NMR spectroscopic analysis and thermoelectrochemistry of lithium-glyme solvate ionic liquids and their dilute solutions', Physical Chemistry Chemical Physics, vol. 20, pp. 16558 - 16567, http://dx.doi.org/10.1039/c8cp02527d
    Journal articles | 2018
    Black JJ; Harper JB; Aldous L, 2018, 'Temperature effect upon the thermoelectrochemical potential generated between lithium metal and lithium ion intercalation electrodes in symmetric and asymmetric battery arrangements', Electrochemistry Communications, vol. 86, pp. 153 - 156, http://dx.doi.org/10.1016/j.elecom.2017.12.005
    Journal articles | 2018
    Hart WES; Aldous L; Harper JB, 2018, 'Nucleophilic Cleavage of Lignin Model Compounds under Acidic Conditions in an Ionic Liquid: A Mechanistic Study', ChemPlusChem, vol. 83, pp. 348 - 353, http://dx.doi.org/10.1002/cplu.201700486
    Journal articles | 2018
    Hawker RR; Haines RS; Harper JB, 2018, 'Predicting solvent effects in ionic liquids: Extension of a nucleophilic aromatic substitution reaction on a benzene to a pyridine', Journal of Physical Organic Chemistry, vol. 31, http://dx.doi.org/10.1002/poc.3862
    Journal articles | 2018
    Hawker RR; Haines RS; Harper JB, 2018, 'Rational selection of the cation of an ionic liquid to control the reaction outcome of a substitution reaction', Chemical Communications, vol. 54, pp. 2296 - 2299, http://dx.doi.org/10.1039/c8cc00241j
    Journal articles | 2018
    Hawker RR; Haines RS; Harper JB, 2018, 'The effect of varying the anion of an ionic liquid on the solvent effects on a nucleophilic aromatic substitution reaction', Organic and Biomolecular Chemistry, vol. 16, pp. 3453 - 3463, http://dx.doi.org/10.1039/c8ob00651b
    Journal articles | 2018
    Hawker RR; Harper JB, 2018, 'Organic Reaction Outcomes in Ionic Liquids', Advances in Physical Organic Chemistry, vol. 52, pp. 49 - 85, http://dx.doi.org/10.1016/bs.apoc.2018.09.001
    Journal articles | 2018
    Hawker RR; Wong MJ; Haines RS; Harper JB, 2018, 'Correction: Rationalising the effects of ionic liquids on a nucleophilic aromatic substitution reaction (Organic and Biomolecular Chemistry (2017) 15 (6433-6440) DOI: 10.1039/C7OB01476G)', Organic and Biomolecular Chemistry, vol. 16, pp. 9069, http://dx.doi.org/10.1039/c8ob90159g
    Journal articles | 2018
    Keaveney ST; Harper JB; Croft AK, 2018, 'Ion-Reagent Interactions Contributing to Ionic Liquid Solvent Effects on a Condensation Reaction', ChemPhysChem, vol. 19, pp. 3279 - 3287, http://dx.doi.org/10.1002/cphc.201800695
    Journal articles | 2018
    Mallo N; Foley ED; Iranmanesh H; Kennedy ADW; Luis ET; Ho J; Harper JB; Beves JE, 2018, 'Structure-function relationships of donor-acceptor Stenhouse adduct photochromic switches', Chemical Science, vol. 9, pp. 8242 - 8252, http://dx.doi.org/10.1039/c8sc03218a
    Journal articles | 2018
    Oss G; De Vos SD; Luc KNH; Harper JB; Nguyen TV, 2018, 'Tropylium-Promoted Oxidative Functionalization of Tetrahydroisoquinolines', Journal of Organic Chemistry, vol. 83, pp. 1000 - 1010, http://dx.doi.org/10.1021/acs.joc.7b02584
    Journal articles | 2018
    Schaffarczyk McHale KS; Haines RS; Harper JB, 2018, 'Ionic Liquids as Solvents for SN2 Processes. Demonstration of the Complex Interplay of Interactions Resulting in the Observed Solvent Effects', ChemPlusChem, vol. 83, pp. 1162 - 1168, http://dx.doi.org/10.1002/cplu.201800510
    Journal articles | 2017
    Beves JE; Harper JB; Thordarson P, 2017, '23rd IUPAC Conference on Physical Organic Chemistry (ICPOC-23)', Pure and Applied Chemistry, vol. 89, pp. 677, http://dx.doi.org/10.1515/pac-2017-0311
    Journal articles | 2017
    Dunn MH; Konstandaras N; Cole ML; Harper JB, 2017, 'Targeted and Systematic Approach to the Study of pKa Values of Imidazolium Salts in Dimethyl Sulfoxide', Journal of Organic Chemistry, vol. 82, pp. 7324 - 7331, http://dx.doi.org/10.1021/acs.joc.7b00716
    Journal articles | 2017
    Hart WES; Aldous L; Harper JB, 2017, 'Cleavage of ethers in an ionic liquid. Enhancement, selectivity and potential application', Organic and Biomolecular Chemistry, vol. 15, pp. 5556 - 5563, http://dx.doi.org/10.1039/c7ob01096f
    Journal articles | 2017
    Hawker RR; Wong MJ; Haines RS; Harper JB, 2017, 'Rationalising the effects of ionic liquids on a nucleophilic aromatic substitution reaction', Organic and Biomolecular Chemistry, vol. 15, pp. 6433 - 6440, http://dx.doi.org/10.1039/c7ob01476g
    Journal articles | 2017
    Keaveney ST; Haines RS; Harper JB, 2017, 'Investigating Solvent Effects of an Ionic Liquid on Pericyclic Reactions through Kinetic Analyses of Simple Rearrangements', ChemPlusChem, vol. 82, pp. 449 - 457, http://dx.doi.org/10.1002/cplu.201600585
    Journal articles | 2017
    Keaveney ST; Haines RS; Harper JB, 2017, 'Ionic liquid solvents: The importance of microscopic interactions in predicting organic reaction outcomes', Pure and Applied Chemistry, vol. 89, pp. 745 - 757, http://dx.doi.org/10.1515/pac-2016-1008
    Journal articles | 2017
    Konstandaras N; Matto L; Bhadbhade M; Hunter L; Harper JB, 2017, 'Synthesis and Determination of the pKa Values of a Series of Bis(anilino)furazano[3, 4-b]pyrazines', ChemistrySelect, vol. 2, pp. 7018 - 7023, http://dx.doi.org/10.1002/slct.201701674
    Journal articles | 2016
    Bluemel M; Crocker RD; Harper JB; Enders D; Nguyen TV, 2016, 'ChemInform Abstract: N-Heterocyclic Olefins as Efficient Phase-Transfer Catalysts for Base-Promoted Alkylation Reactions.', ChemInform, vol. 47, http://dx.doi.org/10.1002/chin.201644051
    Journal articles | 2016
    Blümel M; Crocker RD; Harper JB; Enders D; Nguyen TV, 2016, 'N-Heterocyclic olefins as efficient phase-transfer catalysts for base-promoted alkylation reactions', Chemical Communications, vol. 52, pp. 7958 - 7961, http://dx.doi.org/10.1039/c6cc03771b
    Journal articles | 2016
    Butler BJ; Harper JB, 2016, 'The effect of the structure of the cation of an ionic liquid on the rate of reaction at a phosphorus centre', Journal of Physical Organic Chemistry, vol. 29, pp. 700 - 708, http://dx.doi.org/10.1002/poc.3554
    Journal articles | 2016
    Butler BJ; Thomas DS; Hook JM; Harper JB, 2016, 'ChemInform Abstract: NMR Spectroscopy to Follow Reaction Progress in Ionic Liquids', ChemInform, vol. 47, http://dx.doi.org/10.1002/chin.201632280
    Journal articles | 2016
    Butler BJ; Thomas DS; Hook JM; Harper JB, 2016, 'NMR spectroscopy to follow reaction progress in ionic liquids', Magnetic Resonance in Chemistry, vol. 54, pp. 423 - 428, http://dx.doi.org/10.1002/mrc.4161
    Journal articles | 2016
    Francis DV; Harper JB; Gioia S; Lamb RN; Read RW, 2016, 'Defining surface properties of fluorous bis(1H-1,2,3-triazol-4-ylmethyl) ethers', Journal of Fluorine Chemistry, vol. 183, pp. 36 - 43, http://dx.doi.org/10.1016/j.jfluchem.2016.01.007
    Journal articles | 2016
    Francis DV; Harper JB; Read RW, 2016, 'Titration characteristics of fluorous 1,2,3-triazol-4-ylmethyl ethers, bis(1,2,3-triazol-4-ylmethyl) ethers and bis(1,2,3-triazol-4-ylmethyl) amines', Journal of Fluorine Chemistry, vol. 192, pp. 86 - 97, http://dx.doi.org/10.1016/j.jfluchem.2016.10.012
    Journal articles | 2016
    George SRD; Scott LT; Harper JB, 2016, 'Synthesis of 1-Substituted Fluorenones', Polycyclic Aromatic Compounds, vol. 36, pp. 697 - 715, http://dx.doi.org/10.1080/10406638.2015.1046609
    Journal articles | 2016
    Gondosiswanto R; Gunawan CA; Hibbert DB; Harper JB; Zhao C, 2016, 'Microcontact Printing of Thiol-Functionalized Ionic Liquid Microarrays for "membrane-less" and "spill-less" Gas Sensors', ACS Applied Materials and Interfaces, vol. 8, pp. 31368 - 31374, http://dx.doi.org/10.1021/acsami.6b08876
    Journal articles | 2016
    Hawker RR; Haines RS; Harper JB, 2016, 'ChemInform Abstract: Variation of the Cation of Ionic Liquids: The Effects on Their Physicochemical Properties and Reaction Outcome', ChemInform, vol. 47, http://dx.doi.org/10.1002/chin.201619247
    Journal articles | 2016
    Hawker RR; Panchompoo J; Aldous L; Harper JB, 2016, 'Novel Chloroimidazolium-Based Ionic Liquids: Synthesis, Characterisation and Behaviour as Solvents to Control Reaction Outcome', ChemPlusChem, vol. 81, pp. 574 - 583, http://dx.doi.org/10.1002/cplu.201600099
    Journal articles | 2016
    Keaveney ST; Greaves TL; Kennedy DF; Harper JB, 2016, 'Understanding the Effect of Solvent Structure on Organic Reaction Outcomes When Using Ionic Liquid/Acetonitrile Mixtures', Journal of Physical Chemistry B, vol. 120, pp. 12687 - 12699, http://dx.doi.org/10.1021/acs.jpcb.6b11090
    Journal articles | 2016
    Keaveney ST; Schaffarczyk McHale KS; Stranger JW; Ganbold B; Price WS; Harper JB, 2016, 'NMR Diffusion Measurements as a Simple Method to Examine Solvent–Solvent and Solvent–Solute Interactions in Mixtures of the Ionic Liquid [Bmim][N(SO2CF3)2] and Acetonitrile', ChemPhysChem, vol. 17, pp. 3853 - 3862, http://dx.doi.org/10.1002/cphc.201600927
    Journal articles | 2016
    Keaveney ST; Schaffarczyk McHale KS; Stranger JW; Ganbold B; Price WS; Harper JB, 2016, 'Inside Back Cover: NMR Diffusion Measurements as a Simple Method to Examine Solvent-Solvent and Solvent-Solute Interactions in Mixtures of the Ionic Liquid [Bmim][N(SO2 CF3 )2 ] and Acetonitrile (ChemPhysChem 23/2016)', ChemPhysChem, vol. 17, pp. 4028 - 4028, http://dx.doi.org/10.1002/cphc.201601224
    Journal articles | 2016
    Keaveney ST; White BP; Haines RS; Harper JB, 2016, 'The effects of an ionic liquid on unimolecular substitution processes: The importance of the extent of transition state solvation', Organic and Biomolecular Chemistry, vol. 14, pp. 2572 - 2580, http://dx.doi.org/10.1039/c5ob02598b
    Journal articles | 2016
    Mallo N; Brown PT; Iranmanesh H; MacDonald TSC; Teusner MJ; Harper JB; Ball GE; Beves JE, 2016, 'Photochromic switching behaviour of donor-acceptor Stenhouse adducts in organic solvents', Chemical Communications, vol. 52, pp. 13576 - 13579, http://dx.doi.org/10.1039/C6CC08079K
    Journal articles | 2016
    Schaffarczyk McHale KS; Hawker RR; Harper JB, 2016, 'Nitrogen: Versus phosphorus nucleophiles-how changing the nucleophilic heteroatom affects ionic liquid solvent effects in bimolecular nucleophilic substitution processes', New Journal of Chemistry, vol. 40, pp. 7437 - 7444, http://dx.doi.org/10.1039/c6nj00721j
    Journal articles | 2015
    Butler BJ; Harper JB, 2015, 'Correction: The effect of an ionic liquid on the rate of reaction at a phosphorus centre', New Journal of Chemistry, vol. 39, pp. 1525, http://dx.doi.org/10.1039/c4nj90052a
    Journal articles | 2015
    Butler BJ; Harper JB, 2015, 'The effect of an ionic liquid on the rate of reaction at a phosphorus centre', New Journal of Chemistry, vol. 39, pp. 213 - 219, http://dx.doi.org/10.1039/c4nj01224k
    Journal articles | 2015
    Francis DV; Harper JB; Read RW, 2015, 'Fluorous 1,2,3-Triazol-4-ylmethyl Amines and Amine Derivatives for Novel Surfactant Applications', Australian Journal of Chemistry, vol. 68, pp. 57 - 68, http://dx.doi.org/10.1071/CH14458
    Journal articles | 2015
    George SRD; Elton TE; Harper JB, 2015, 'Electronic effects on the substitution reactions of benzhydrols and fluorenyl alcohols. Determination of mechanism and effects of antiaromaticity', Organic and Biomolecular Chemistry, vol. 13, pp. 10745 - 10750, http://dx.doi.org/10.1039/c5ob01637a
    Journal articles | 2015
    George SRD; Frith TDH; Thomas DS; Harper JB, 2015, 'Putting corannulene in its place. Reactivity studies comparing corannulene with other aromatic hydrocarbons', Organic and Biomolecular Chemistry, vol. 13, pp. 9035 - 9041, http://dx.doi.org/10.1039/c5ob01215e
    Journal articles | 2015
    Hart WES; Harper JB; Aldous L, 2015, 'The effect of changing the components of an ionic liquid upon the solubility of lignin†', Green Chemistry, vol. 17, pp. 214 - 218, http://dx.doi.org/10.1039/c4gc01888e
    Journal articles | 2015
    Keaveney ST; Francis DV; Cao W; Haines RS; Harper JB, 2015, 'Effect of Modifying the Anion of an Ionic Liquid on the Outcome of an SN2 Process', Australian Journal of Chemistry, vol. 68, pp. 31 - 35, http://dx.doi.org/10.1071/CH14117
    Journal articles | 2015
    Keaveney ST; Haines RS; Harper JB, 2015, 'Developing principles for predicting ionic liquid effects on reaction outcome. the importance of the anion in controlling microscopic interactions', Organic and Biomolecular Chemistry, vol. 13, pp. 3771 - 3780, http://dx.doi.org/10.1039/c4ob02482f
    Journal articles | 2015
    Keaveney ST; Haines RS; Harper JB, 2015, 'Ionic liquid effects on a multistep process. Increased product formation due to enhancement of all steps', Organic and Biomolecular Chemistry, vol. 13, pp. 8925 - 8936, http://dx.doi.org/10.1039/c5ob01214g
    Journal articles | 2015
    Keaveney ST; Harper JB; Croft AK, 2015, 'ChemInform Abstract: Computational Approaches to Understanding Reaction Outcomes of Organic Processes in Ionic Liquids', ChemInform, vol. 46, pp. no - no, http://dx.doi.org/10.1002/chin.201527319
    Journal articles | 2015
    Keaveney ST; Harper JB; Croft AK, 2015, 'Computational approaches to understanding reaction outcomes of organic processes in ionic liquids', RSC Advances, vol. 5, pp. 35709 - 35729, http://dx.doi.org/10.1039/c4ra14676j
    Journal articles | 2015
    Yau HM; Haines RS; Harper JB, 2015, 'A robust, "one-pot" method for acquiring kinetic data for hammett plots used to demonstrate transmission of substituent effects in reactions of aromatic ethyl esters', Journal of Chemical Education, vol. 92, pp. 538 - 542, http://dx.doi.org/10.1021/ed400701m
    Journal articles | 2015
    Yau HM; Keaveney ST; Butler BJ; Tanner EEL; Guerry MS; George SRD; Dunn MH; Croft AK; Harper JB, 2015, 'ChemInform Abstract: Towards Solvent-Controlled Reactivity in Ionic Liquids', ChemInform, vol. 46, pp. no - no, http://dx.doi.org/10.1002/chin.201516364
    Journal articles | 2014
    Ahmed MI; Harper JB; Hunter L, 2014, 'Incrementally increasing the length of a peptide backbone: Effect on macrocyclisation efficiency', Organic and Biomolecular Chemistry, vol. 12, pp. 4598 - 4601, http://dx.doi.org/10.1039/c4ob00492b
    Journal articles | 2014
    Harper JB; Khabnadideh K, 2014, 'Effect of ionic liquid (Bmim[NTf2]) on the rate of reaction in the synthesis of some new azole compounds as antifungal agents', Science Research, vol. 2, pp. 125 - 131
    Journal articles | 2014
    Keaveney ST; Schaffarczyk McHale KS; Haines RS; Harper JB, 2014, 'Developing principles for predicting ionic liquid effects on reaction outcome. A demonstration using a simple condensation reaction', Organic and Biomolecular Chemistry, vol. 12, pp. 7092 - 7099, http://dx.doi.org/10.1039/c4ob01070a
    Journal articles | 2013
    Keaveney ST; Harper JB, 2013, 'Towards reaction control using an ionic liquid: Biasing outcomes of reactions of benzyl halides', RSC Advances, vol. 3, pp. 15698 - 15704, http://dx.doi.org/10.1039/c3ra42820f
    Journal articles | 2013
    Tanner EEL; Hawker RR; Yau HM; Croft AK; Harper JB, 2013, 'Probing the importance of ionic liquid structure: A general ionic liquid effect on an SNAr process', Organic and Biomolecular Chemistry, vol. 11, pp. 7516 - 7521, http://dx.doi.org/10.1039/c3ob41634h
    Journal articles | 2013
    Tanner EEL; Yau HM; Hawker RR; Croft AK; Harper JB, 2013, 'Does the cation really matter? the effect of modifying an ionic liquid cation on an SN2 process', Organic and Biomolecular Chemistry, vol. 11, pp. 6170 - 6175, http://dx.doi.org/10.1039/c3ob41038b
    Journal articles | 2013
    Yau HM; Keaveney ST; Butler BJ; Tanner EEL; Guerry MS; George SRD; Dunn MH; Croft AK; Harper JB, 2013, 'Towards solvent-controlled reactivity in ionic liquids', Pure and Applied Chemistry, vol. 85, pp. 1979 - 1990, http://dx.doi.org/10.1351/PAC-CON-12-10-22
    Journal articles | 2012
    Hua C; Zhang WH; De Almeida SRM; Ciampi S; Gloria D; Liu G; Gooding JJ; Harper JB, 2012, 'A novel route to copper(II)detection using ‘click’ chemistry- induced aggregation of gold nanoparticles', Analyst, vol. 137, pp. 82 - 86, http://dx.doi.org/10.1039/C1AN15693D
    Journal articles | 2012
    Ng A; Magenau AI; Hawa SH; Ciampi S; Chockalingam M; Harper JB; Gaus K; Gooding JJ, 2012, 'Using an electrical potential to reversibly switch surfaces between two states for dynamically controlling cell adhesion', Angewandte Chemie (International Edition), vol. 51, pp. 7706 - 7710, http://dx.doi.org/10.1002/anie.201202118
    Journal articles | 2012
    Ng CCA; Magenau A; Ngalim SH; Ciampi S; Chockalingham M; Harper JB; Gaus K; Gooding JJ, 2012, 'Using an Electrical Potential to Reversibly Switch Surfaces between Two States for Dynamically Controlling Cell Adhesion', Angewandte Chemie, vol. 124, pp. 7826 - 7830, http://dx.doi.org/10.1002/ange.201202118
    Journal articles | 2012
    Yau HM; Croft A; Harper JB, 2012, 'Investigating the origin of entropy-derived rate accelerations in ionic liquids', Faraday Discussions, vol. 154, pp. 365 - 371, http://dx.doi.org/10.1039/c1fd00060h
    Journal articles | 2011
    Butler B; Hook JM; Harper JB, 2011, 'Recent Advances in the NMR Spectroscopy of Chlorine, Bromine and Iodine', Annual Reports on Nmr Spectroscopy, vol. 73, pp. 63 - 82, http://dx.doi.org/10.1016/B978-0-08-097074-5.00002-5
    Journal articles | 2011
    Butler BJ; Hook JM; Harper JB, 2011, 'ChemInform Abstract: Recent Advances in the NMR Spectroscopy of Chlorine, Bromine and Iodine', ChemInform, vol. 42, pp. no - no, http://dx.doi.org/10.1002/chin.201141279
    Journal articles | 2011
    Ciampi S; James M; Guan B; Harper JB; Gooding JJ; Darwish N; Luais E, 2011, 'Oxidative acetylenic coupling reactions as a surface chemistry tool', Physical Chemistry Chemical Physics, vol. 13, pp. 15624 - 15632, http://dx.doi.org/10.1039/c1cp21450k
    Journal articles | 2010
    BADRAN TW; CHAI CLL; EASTON CJ; HARPER JB; PAGE DM, 2010, 'ChemInform Abstract: Directing Bromination of Piperazine-2,5-diones.', ChemInform, vol. 26, pp. no - no, http://dx.doi.org/10.1002/chin.199544171
    Journal articles | 2010
    Ciampi S; Harper JB; Gooding JJ, 2010, 'ChemInform Abstract: Wet Chemical Routes to the Assembly of Organic Monolayers on Silicon Surfaces via the Formation of Si-C Bonds: Surface Preparation, Passivation and Functionalization', ChemInform, vol. 41, http://dx.doi.org/10.1002/chin.201042248
    Journal articles | 2010
    Ciampi S; Harper JB; Gooding JJ, 2010, 'Wet chemical routes to the assembly of organic monolayers on silicon surfaces via the formation of Si–C bonds: surface preparation, passivation and functionalization', Chemical Society Reviews, vol. 39, pp. 2158 - 2183, http://dx.doi.org/10.1039/b923890p
    Journal articles | 2010
    Croft AK; Harper JB; Yau HM; Jones SG; Barnes SA; Hook JM, 2010, 'Ionic liquid impact on reaction outcomes: A rational mechanism-based approach', ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 240, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208164705053&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2010
    Davies E; Huang Y; Harper JB; Hook JM; Thomas DS; Burgar IM; Lillford PJ, 2010, 'Dynamics of water in agar gels studied using low and high resolution 1H NMR spectroscopy', International Journal of Food Science and Technology, vol. 45, pp. 2502 - 2507, http://dx.doi.org/10.1111/j.1365-2621.2010.02448.x
    Journal articles | 2010
    EASTON CJ; HARPER JB, 2010, 'ChemInform Abstract: Acylase I Catalyzed Hydrolysis of para-Substituted (S)-Phenylalanine Derivatives from Mixtures of the Racemic ortho- and para-Substituted Isomers.', ChemInform, vol. 29, pp. no - no, http://dx.doi.org/10.1002/chin.199841205
    Journal articles | 2010
    George SRD; Edwards GL; Harper JB, 2010, 'The effects of ionic liquids on azide-alkyne cycloaddition reactions', Organic and Biomolecular Chemistry, vol. 8, pp. 5354 - 5358, http://dx.doi.org/10.1039/C0OB00306A
    Journal articles | 2010
    Gui AL; Liu G; Chockalingham M; Le saux G; Harper JB; Gooding JJ, 2010, 'A Comparative Study of Modifying Gold and Carbon Electrode with 4-Sulfophenyl Diazonium Salt', Electroanalysis, vol. 22, pp. 1283 - 1289, http://dx.doi.org/10.1002/elan.200900615
    Journal articles | 2010
    Gui AL; Liu G; Chockalingham M; Le saux G; Harper JB; Gooding JJ, 2010, 'A comparative study of electrochemical reduction of 4-nitrophenyl covalently grafted on gold and carbon', Electroanalysis, vol. 22, pp. 1824 - 1830, http://dx.doi.org/10.1002/elan.201000164
    Journal articles | 2010
    Jones SG; Yau HM; Davies E; Hook JM; Youngs TGA; Harper JB; Croft AK, 2010, 'Ionic liquids through the looking glass: theory mirrors experiment and provides further insight into aromatic substitution processes', Physical Chemistry Chemical Physics, vol. 12, pp. 1873 - 1878, http://dx.doi.org/10.1039/b919831h
    Journal articles | 2010
    Ng A; Ciampi S; Harper JB; Gooding JJ, 2010, 'Antifouling behaviour of silicon surfaces modified with self-assembled monolayers containing both ethylene glycol and charged moieties', Surface Science, vol. 604, pp. 1388 - 1394, http://dx.doi.org/10.1016/j.susc.2010.04.025
    Journal articles | 2009
    Chan S; Howe AG; Hook JM; Harper JB, 2009, '79Br NMR spectroscopy as a practical tool for kinetic analysis', Magnetic Resonance in Chemistry, vol. 47, pp. 342 - 347, http://dx.doi.org/10.1002/mrc.2401
    Journal articles | 2009
    Ciampi S; Eggers PK; Le Saux G; James M; Harper JB; Gooding JJ; Le Saux G, 2009, 'Silicon (100) electrodes resistant to oxidation in aqueous solutions: An unexpected benefit of surface acetylene moieties', Langmuir, vol. 25, pp. 2530 - 2539, http://dx.doi.org/10.1021/la803710d
    Journal articles | 2009
    Ng A; Ciampi S; James M; Harper JB; Gooding JJ, 2009, 'Comparing the Reactivity of Alkynes and Alkenes on Silicon (100) Surfaces', Langmuir, vol. 25, pp. 13934 - 13941, http://dx.doi.org/10.1021/la901526e
    Journal articles | 2009
    Ng M; Craig D; Harper JB; Van-Eijck L; Stride JA, 2009, 'The central atom size effect on the structure of group 14 tetratolyls', Chemistry - a European Journal, vol. 15, pp. 6569 - 6572, http://dx.doi.org/10.1002/chem.200900360
    Journal articles | 2009
    Rosella C; Harper JB, 2009, 'The effect of ionic liquids on the outcome of nitrile oxide cycloadditions', Tetrahedron Letters, vol. 50, pp. 992 - 994, http://dx.doi.org/10.1016/j.tetlet.2008.12.045
    Journal articles | 2009
    Yau HM; Chan S; George S; Hook JM; Croft A; Harper JB, 2009, 'Ionic liquids: Just molten salts after all?', Molecules, vol. 14, pp. 2521 - 2534, http://dx.doi.org/10.3390/molecules14072521
    Journal articles | 2009
    Yau HM; Howe AG; Hook JM; Croft A; Harper JB, 2009, 'Solvent reorganisation as the driving force for rate changes of Menschutkin reactions in an ionic liquid', Organic and Biomolecular Chemistry, vol. 7, pp. 3572 - 3575, http://dx.doi.org/10.1039/b909171h
    Journal articles | 2008
    Ciampi S; Boecking T; Kilian KA; Harper JB; Gooding JJ, 2008, 'Click chemistry in mesoporous materials: Functionalization of porous silicon rugate filters', Langmuir, vol. 24, pp. 5888 - 5892, http://dx.doi.org/10.1021/la800435d
    Journal articles | 2008
    Ciampi S; Le Saux G; Harper JB; Gooding JJ, 2008, 'Optimization of click chemistry of ferrocene derivatives on acetylene-functionalized silicon(100) surfaces', Electroanalysis, vol. 20, pp. 1513 - 1519, http://dx.doi.org/10.1002/elan.200804241
    Journal articles | 2008
    Clayton KA; Black DS; Harper JB, 2008, 'Mechanisms of cyclisation of indolo oxime ethers. Part 2: Formation of ethyl 6,8-dimethoxypyrazolo[4,5,1-hi]indole-5-carboxylates', Tetrahedron, vol. 64, pp. 3183 - 3189, http://dx.doi.org/10.1016/j.tet.2008.01.100
    Journal articles | 2008
    Lynden-Bell RM; Del Popolo MG; Youngs TGA; Kohanoff J; Hanke CG; Harper JB; Pinilla CG, 2008, 'ChemInform Abstract: Simulations of Ionic Liquids, Solutions, and Surfaces', ChemInform, vol. 39, http://dx.doi.org/10.1002/chin.200806272
    Journal articles | 2008
    Yau HM; Barnes S; Hook JM; Youngs T; Croft A; Harper JB, 2008, 'The importance of solvent reorganisation in the effect of an ionic liquid on a unimolecular substitution process', Chemical Communications, pp. 3576 - 3578, http://dx.doi.org/10.1039/b805255g
    Journal articles | 2007
    Ciampi S; Boecking T; Kilian KA; James M; Harper JB; Gooding JJ, 2007, 'Functionalization of acetylene-terminated monolayers on Si(100) surfaces: A click chemistry approach', Langmuir, vol. 23, pp. 9320 - 9329, http://dx.doi.org/10.1021/la701035g
    Journal articles | 2007
    Clayton KA; Black DS; Harper JB, 2007, 'Mechanisms of cyclisation of indolo oxime ethers I. Formation of ethyl 9,11-dimethoxy indolo[2,3-c] quinoline-6-carboxylates', Tetrahedron, vol. 63, pp. 10615 - 10621, http://dx.doi.org/10.1016/j.tet.2007.08.026
    Journal articles | 2007
    Lynden-Bell RM; Del Popolo M; Youngs T; Kohanoff J; Hanke CG; Harper JB; Pinilla C, 2007, 'Simulations of ionic liquids, solutions, and surfaces', Accounts of Chemical Research, vol. 40, pp. 1138 - 1145, http://dx.doi.org/10.1021/ar700065s
    Journal articles | 2007
    Pouwer R; Harper JB; Vyakaranam K; Michl J; Williams CM; Jessen C; Bernhardt PV, 2007, 'Investigating direct alkynylation at the bridgehead of bicyclic cages using silver(I) acetylides', European Journal of Organic Chemistry, pp. 241 - 248, http://dx.doi.org/10.1002/ejoc.200600701
    Journal articles | 2007
    Pouwer RH; Harper JB; Vyakaranam K; Michl J; Williams CM; Jessen CH; Bernhardt PV, 2007, 'Cover Picture: Investigating Direct Alkynylation at the Bridgehead of Bicyclic Cages Using Silver(I) Acetylides (Eur. J. Org. Chem. 2/2007)', European Journal of Organic Chemistry, vol. 2007, pp. 215 - 215, http://dx.doi.org/10.1002/ejoc.200790002
    Journal articles | 2007
    Pratt M; Harper JB; Colbran SB, 2007, 'Do (pentaarylcyclopentadienyl)molybdenum(vi) dioxo species catalyse alkene epoxidations? Insights from kinetics data', Journal of the Royal Chemical Society, Dalton Transactions, pp. 2746 - 2748, http://dx.doi.org/10.1039/b705571d
    Journal articles | 2006
    Black DS; Channon M; Clayton KA; Condie GC; Harper JB; Kumar N; Pchalek K; Wahyuningsih TD, 2006, 'Augmented Indoles', Arkivoc, vol. 2006, pp. 67 - 75
    Journal articles | 2006
    Black DSC; Channon MF; Clayton KA; Condie GC; Harper JB; Kumar N; Pchalek K; Wahyuningsih TD, 2006, 'Augmented Indoles', ChemInform, vol. 37, http://dx.doi.org/10.1002/chin.200615247
    Journal articles | 2006
    Harper JB; Kobrak M, 2006, 'Understanding organic processes in ionic liquids: Achievements so far and challenges remaining', MINI-REVIEWS IN ORGANIC CHEMISTRY, vol. 3, pp. 253 - 269, http://dx.doi.org/10.2174/157019306777935037
    Journal articles | 2006
    Harper JB; Kobrak MN, 2006, 'Understanding Organic Processes in Ionic Liquids: Achievements So Far and Challenges Remaining', ChemInform, vol. 37, http://dx.doi.org/10.1002/chin.200649267
    Journal articles | 2006
    Lawes DJ; Darwish T; Clark T; Harper JB; Ball GE, 2006, 'A rhenium-cyclohexane complex with preferential binding of axial C-H bonds: A probe into the relative ability of C-H, C-D, and C-C bonds as hyperconjugative electron donors?', Angewandte Chemie (International Edition), vol. 45, pp. 4486 - 4490, http://dx.doi.org/10.1002/anie.200600313
    Journal articles | 2006
    Lawes DJ; Darwish TA; Clark T; Harper JB; Ball GE, 2006, 'A Rhenium–Cyclohexane Complex with Preferential Binding of Axial CH Bonds: A Probe into the Relative Ability of CH, CD, and CC Bonds as Hyperconjugative Electron Donors?', Angewandte Chemie, vol. 118, pp. 4598 - 4602, http://dx.doi.org/10.1002/ange.200600313
    Journal articles | 2006
    Sim A; Harper J; Zareie H; James M; Singh N, 2006, 'Phenyl-terminated self assembled monolayers on Si(100) for low voltage transistor applications', 2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings, vol. 3, pp. 70 - 73
    Journal articles | 2005
    Ji XK; Black DS; Colbran SB; Craig DC; Edbey KM; Harper JB; Willett GD, 2005, 'meso-Indanyl calix[4]pyrrole receptors', Tetrahedron, vol. 61, pp. 10705 - 10712, http://dx.doi.org/10.1016/j.tet.2005.08.082
    Journal articles | 2005
    Man BY; Hook JM; Harper JB, 2005, 'Substitution reactions in ionic liquids. A kinetic study', Tetrahedron Letters, vol. 46, pp. 7641 - 7645, http://dx.doi.org/10.1016/j.tetlet.2005.08.064
    Journal articles | 2005
    Pouwer R; Williams CM; Raine A; Harper JB, 2005, '`One-Step` alkynylation of adamantyl iodide with Silver(I) acetylides', Organic Letters, vol. 7, pp. 1323 - 1325, http://dx.doi.org/10.1021/ol050121+
    Journal articles | 2005
    Pouwer RH; Williams CM; Raine AL; Harper JB, 2005, '“One-Step” Alkynylation of Adamantyl Iodide with Silver(I) Acetylides.', ChemInform, vol. 36, http://dx.doi.org/10.1002/chin.200532082
    Journal articles | 2004
    Barr L; Dumanski PG; Easton CJ; Harper JB; Lee K; Lincoln SF; Meyer AG; Simpson JS, 2004, 'Cyclodextrin Molecular Reactors', Journal Of Inclusion Phenomena, vol. 50, pp. 19 - 24, http://dx.doi.org/10.1007/s10847-003-8833-9
    Journal articles | 2004
    Harper JB; Lynden-Bell RM, 2004, 'Macroscopic and microscopic properties of solutions of aromaticcompounds in an ionic liquid', Molecular Physics, vol. 102, pp. 85 - 94, http://dx.doi.org/10.1080/00268970410001668570
    Journal articles | 2004
    Paxton A; Harper JB, 2004, 'On the solvation of L-aspartic acid', Molecular Physics, vol. 102, pp. 953 - 958, http://dx.doi.org/10.1080/00268970410001711913
    Journal articles | 2004
    Paxton AT; Harper JB, 2004, 'Erratum: On the solvation of L-aspartic acid (Moleculer Physics 102:9-10 (953-958))', Molecular Physics, vol. 102, pp. 1981, http://dx.doi.org/10.1080/0026897042000297293
    Journal articles | 2003
    Hanke CG; Johansson A; Harper JB; Lynden-Bell RM, 2003, 'Why are aromatic compounds more soluble than aliphatic compounds in dimethylimidazolium ionic liquids? A simulation study', Chemical Physics Letters, vol. 374, pp. 85 - 90, http://dx.doi.org/10.1016/S0009-2614(03)00703-6
    Journal articles | 2003
    Harper JB; Easton CJ; Lincoln SF, 2003, 'A cyclodextrin-based molecular reactor to template the formation of indigoid dyes', Tetrahedron Letters, vol. 44, pp. 5815 - 5818, http://dx.doi.org/10.1016/S0040-4039(03)01403-5
    Journal articles | 2001
    Easton CJ; Harper JB; Head SJ; Lee K; Lincoln SF, 2001, 'Cyclodextrins to limit substrate inhibition and alter substrate selectivity displayed by enzymes', Journal of the Chemical Society. Perkin Transactions 1, pp. 584 - 587, http://dx.doi.org/10.1039/b008339i
    Journal articles | 2000
    Harper JB; Easton CJ; Lincoln SF, 2000, 'ChemInform Abstract: Cyclodextrins to Increase the Utility of Enzymes in Organic Synthesis', ChemInform, vol. 31, pp. no - no, http://dx.doi.org/10.1002/chin.200047269
    Journal articles | 2000
    Harper JB; Easton CJ; Lincoln SF, 2000, 'Cyclodextrins to increase the utility of enzymes in organic synthesis', Current Organic Chemistry, vol. 4, pp. 429 - 454, http://dx.doi.org/10.2174/1385272003376247
    Journal articles | 1998
    Easton CJ; Harper JB, 1998, 'Acylase I catalysed hydrolysis of para-substituted (S)-phenylalanine derivatives from mixtures of the racemic ortho- and para-substituted isomers', Tetrahedron Letters, vol. 39, pp. 5269 - 5272, http://dx.doi.org/10.1016/S0040-4039(98)00997-6
    Journal articles | 1998
    Easton CJ; Harper JB; Lincoln SF, 1998, 'N,N′-bis(6A-deoxy-β-cyclodextrin-6 A-yl)urea as a molecular template in the formation of indigoid dyes', New Journal of Chemistry, vol. 22, pp. 1163 - 1165, http://dx.doi.org/10.1039/a806486e
    Journal articles | 1997
    Ashnagar A; Culnane PT; Easton CJ; Harper JB; Lincoln SF, 1997, 'Complexes of Naproxen and Ibuprofen with 6(A)-amino-6(A)-deoxy-beta-cyclodextrin', AUSTRALIAN JOURNAL OF CHEMISTRY, vol. 50, pp. 447 - 450, http://dx.doi.org/10.1071/C96201
    Journal articles | 1997
    Ashnagar A; Tin Culnane P; Easton CJ; Harper JB; Lincoln SF, 1997, 'Complexes of naproxen and ibuprofen with 6A-amino-6A-deoxy-β-cyclodextrin', Australian Journal of Chemistry, vol. 50, pp. 447 - 450, http://dx.doi.org/10.1071/C96201
    Journal articles | 1995
    Badran TW; Easton CJ; Harper JB, 1995, 'Directing bromination of piperazine-2, 5-diones', Australian Journal of Chemistry, vol. 48, pp. 1379 - 1384, http://dx.doi.org/10.1071/CH9951379
    Journal articles | 1995
    Easton CJ; Harper JB; Lincoln SF, 1995, 'Use of cyclodextrins to limit product inhibition of (S)-phenylalanine ammonia lyase', Journal of the Chemical Society, Perkin Transactions 1, pp. 2525 - 2526, http://dx.doi.org/10.1039/p19950002525
  • Conference Papers | 2010
    Khor SM; Liu G; Harper JB; Iyengar SG; Gooding JJ, 2010, 'Strategies for fabricating a biorecognition interface for a label free electrochemical immunosensor', in ICONN 2012 - Proceedings of the 2012 International Conference on Nanoscience and Nanotechnology, Australian Nanotechnology Network, Perth WA Australia, pp. 230 - 233, presented at 2010 3rd International Conference on Nanoscience and Nanotechnology, ICONN 2010, Sydney, NSW, Australia, 22 February 2010 - 26 February 2010, http://dx.doi.org/10.1109/ICONN.2010.6045168
    Conference Papers | 2007
    Man BY; Howe AG; Yau HM; Rosella C; Hook JM; Harper JB, 2007, 'Towards an understanding of organic processes in ionic liquids', in 4th Heron Island Conference on Reactive Intermediates and Unusual Molecules, 4th Heron Island Conference on Reactive Intermediates and Unusual Molecules, Heron Island, Australia, pp. 12 - 12, presented at 4th Heron Island Conference on Reactive Intermediates and Unusual Molecules, Heron Island, Australia, 07 July 2007 - 14 July 2007
    Conference Papers | 2006
    Black DS; Harper JB; Kumar N; Condie GC; Clayton KA; Wahyuningsih TD, 2006, 'Recent developments in natural and unnatural indoles', in Arbain (ed.), XIIth Asian Symposium on Medicinal Plants, Spices and Other natural Products (ASOMPS XII), XIIth Asian Symposium on Medicinal Plants, Spices and Other natural Products (ASOMPS XII), Padang, Indonesia, pp. 22 - 22, presented at XIIth Asian Symposium on Medicinal Plants, Spices and Other natural Products (ASOMPS XII), Padang, Indonesia, 13 November 2006 - 18 November 2006
    Conference Proceedings (Editor of) | 2005
    Chan BK; Harper JB; Jones MW; Read RW, (eds.), 2005, '20th International Congress of Heterocyclic Chemistry', Palermo, Italy, presented at 20th International Congress of Heterocyclic Chemistry, Palermo, Italy, 31 July 2005 - 05 August 2005
    Conference Papers | 2005
    Harper JB; Hook JM; Man BY, 2005, 'Towards An Understanding of Substitution Reactions in Ionic Liquids - Oral Abstracts', in Apte S; Kable S; Baker AT (eds.), Connect 2005 - Chemical Challenges for the 21st Century, Connect 2005 - Chemical Challenges for the 21st Century, Sydney, Conbvention Centre, Darling Harbour, Sydney, pp. 241 - 241, presented at Connect 2005 - Chemical Challenges for the 21st Century, Sydney, Conbvention Centre, Darling Harbour, Sydney, 03 July 2005 - 07 July 2005
    Conference Papers | 2005
    Lawes DJ; Geftakis S; Harper JB; Ball GE, 2005, 'Insight into Binding Preferences and Exchange in Alkane Complexes, using NMR Spectroscopy', in Apte S; Kable S; Baker AT (eds.), Connect 2005 - Chemical Challenges for the 21st Century, Connect 2005 - Chemical Challenges for the 21st Century, Sydney, Conbvention Centre, Darling Harbour, Sydney, pp. 036 - -, presented at Connect 2005 - Chemical Challenges for the 21st Century, Sydney, Conbvention Centre, Darling Harbour, Sydney, 03 July 2005 - 07 July 2005
    Conference Papers | 2004
    Barr L; Dumanski PG; Easton CJ; Harper JB; Lee K; Lincoln SF; Meyer AG; Simpson JS, 2004, 'Cyclodextrin molecular reactors', in Journal of Inclusion Phenomena, pp. 19 - 24, http://dx.doi.org/10.1007/s10847-004-8833-9
    Conference Papers | 1998
    Easton CJ; Harper JB; Lincoln SF, 1998, 'Cyclodextrins as molecular templates', in Labandeira JJT; VilaJato JL (ed.), PROCEEDINGS OF THE 9TH INTERNATIONAL SYMPOSIUM ON CYCLODEXTRINS, SPRINGER, SANTIAGO COMPOSTE, SPAIN, pp. 541 - 543, presented at 9th International Symposium on Cyclodextrins, SANTIAGO COMPOSTE, SPAIN, 31 May 1998 - 03 June 1998, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000084438900129&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Preprints |
    Doak B; Whitehouse R; Rimmer K; Williams M; Heras B; Caria S; Ilyichova O; Vazirani M; Mohanty B; Harper J; Scanlon M; Simpson J, Fluoromethylketone-fragment conjugates designed as covalent modifiers of EcDsbA are atypical substrates, http://dx.doi.org/10.26434/chemrxiv-2022-262lh
    Preprints |
    Munavirov B; Black JJ; Shah FU; Leckner J; Rutland MW; Harper JB; Glavatskih S, The Effect of Anion Architecture on the Lubrication Chemistry of Phosphonium Orthoborate Ionic Liquid, http://dx.doi.org/10.21203/rs.3.rs-849341/v1

"Designer ionic liquids to control reaction outcome: Ionic liquids for solvent-controlled reactivity", Jason B. Harper, William S. Price, ARC Discovery Projects (2018-2020)

"Getting the reaction outcomes you want in ionic liquids: Towards solvent-controlled reactivity using ionic liquids". Jason B. Harper, Lawrence T. Scott, ARC Discovery Projects (2013-2015)

C. J. Martin Postdoctoral Fellow, 2000-2002

For more information on all of these research projects and where they sit in the ongoing scheme of the research group, please see the group website at www.jasonbharper.com

Our research is focused on understanding how organic processes happen and what affects reaction outcomes.  Particularly this encompasses examining how structural features in both the reagents themselves and the solvent used can change how a reaction proceeds.  This knowledge can then be applied to a range of fields, including bioorganic, synthetic, analytical and environmental chemistry.  Being particularly interdisciplinary, there is extensive opportunity for collaboration and this is currently underway in the areas of catalysis, reaction kinetics, synthesis and molecular dynamics simulations.

The major areas of research are:

 

Ionic liquid effects on organic reactions: understanding solvation, designing better solvents and getting the reaction outcomes you want!

Ionic liquids are salts that melt below 100 °C.  They have the potential to replace volatile organic solvents but outcomes of reactions in ionic liquids are often different to those in traditional molecular solvents. The aim of this project is to understand the nature of solvation in these systems – the interactions between a solute and the ions of the ionic liquid – through analysis of reaction outcomes, measurements of solution properties (such as diffusion) and molecular dynamics simulations.  The result would be to extend the understanding of these solvent effects we have developed and to use this knowledge to control reaction outcome.

The project would involve kinetic  analyses using NMR spectroscopy to monitor the progress of reactions, along with synthetic organic and analytical chemistry.  Importantly, it can be readily tailored to either the physical and analytical aspects, with the opportunity to focus on methods to measure interactions and molecular dynamics simulations, or the more synthetic aspects, by focussing on designing new ionic liquids, increasing reaction yield and optimising isolation.  Either way, you will be designing solvents to get the reaction outcome you want.

This project is in collaboration with Dr Ron Haines & Prof. Stuart Prescott, UNSW; Prof.’s Anna Croft & Christof Jäger, University of Nottingham; Prof. Bill Price, Western Sydney University; Prof. Tam Greaves, RMIT University.)

 

Catalysis using N-heterocyclic carbenes: understanding structure-activity relationships

N-Heterocyclic carbenes, have significant roles in both organo- and organometallic catalysis, however some carbenes are effective for some processes but not for others; the origin of this is not well understood.  This project aims to relate the tructure and chemical properties of carbenes to catalytic efficacy; particularly the effects of changing steric and electronic properties will be assessed.  Along with making the precursors to the carbenes, this project involves the opportunity to utilise various characterisation techniques (such as measuring acidity of parent cations to generating electronic probes based on Pd and Se) along with evaluation of catalytic systems; the latter can vary from screening of catalysts to detailed kinetic analyses.  The ultimate goal is to be able to rationally choose an NHC catalyst for a given process.

 

Non-planar aromatic hydrocarbons: different reactivity based on structure

Aromatic hydrocarbons are meant to be planar – right?  Yet the synthesis of carbon nanotubes and related structures relies on the reactivity of curved aromatic systems.  This project focuses on the different reactivities of these systems relative to 'normal' aromatics and how it might be controlled and exploited.  It will predominantly involve synthesis and reactivity of systems, such as those shown below, with the opportunity for some kinetic studies to interpret the reactivity.  Ultimately, understanding and exploiting these differences will allow the rational synthesis of these curved polyarenes.

This project is in collaboration with Prof. Larry Scott (Boston College).

 

Broader applications of physical organic chemistry

The understanding developed above can be applied broadly – from understanding lubrication mechanisms to develop new compounds for mechanical engineering throught to the preparation of samples to evaluate ancient climates.  These projects focus on the ability to transfer understanding from one context to another and the skill sets required vary dramatically between projects.  However, they all would suit someone with an interest in combining chemistry with an outside discipline as there will be opportunities to work closely with collaborators in different fields.  Ultimately, these projects seek to expand the impact of the knowledge gained through our fundamental research.

This project is in collaboration with Drs Jeffrey Black, Jonathan Palmer, Chris Marjo and Prof. Chris Tierney, UNSW; Prof.’s Sergei Glavitskih and Mark Rutland, KTH, Stockholm.

 

 

 

 

 

Assoc. Prof. Harper teaches a range of courses across the School of Chemistry.  For more details, see https://www.chemistry.unsw.edu.au/current-students/undergraduate/courses