Professor Jerry Greenfield
Professor

Professor Jerry Greenfield

MBBS (BSc Med), PhD, FRACP

Medicine & Health
School of Clinical Medicine

Professor Greenfield is an Endocrinologist and Clinical researcher. He is Head of Department, Endocrinology and Director, Diabetes Services, at St Vincent’s Hospital; Head, St Vincent's Clinical Campus and Professor of Medicine, University of New South Wales.

Professor Greenfield is Editorial Board member, Clinical Obesity and an Executive Council Member, Australian Diabetes Society.

He previously held an NHMRC Neil Hamilton Fairley Postdoctoral Research Fellowship, which allowed him to study in the Departments of Medicine and Clinical Biochemistry, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK (2005-6, Supervisors: Prof Stephen O’Rahilly and Dr Sadaf Farooqi). He undertook a PhD at the Garvan Institute from 2001-2004, under the supervision of Prof D Chisholm, Prof L Campbell and Prof K Samaras). He graduated from the Faculty of Medicine with Honours (class 1) from the University of NSW in 1995.

Phone
02 8382 2622
Location
Garvan Institute of Medical Research 384 Victoria Street DARLINGHURST NSW 2010
  • Journal articles | 2023
    Lasschuit JWJ; Greenfield JR; Tonks KTT, 2023, 'Response to the Letter to the Editor regarding “Contribution of peripheral neuropathy to poor bone health in the feet of people with type 2 diabetes mellitus”', Acta Diabetologica, http://dx.doi.org/10.1007/s00592-023-02052-9
    Journal articles | 2023
    Sheu A; Greenfield JR; White CP; Center JR, 2023, 'Contributors to impaired bone health in type 2 diabetes', Trends in Endocrinology and Metabolism, vol. 34, pp. 34 - 48, http://dx.doi.org/10.1016/j.tem.2022.11.003
    Journal articles | 2023
    Snaith JR; Greenfield JR, 2023, 'Once-Weekly Semaglutide in Adolescents with Obesity.', N Engl J Med, vol. 388, pp. 1145, http://dx.doi.org/10.1056/NEJMc2300510
    Journal articles | 2022
    Bennett MJ; Balcerek MI; Lewis EAD; Zhang RLL; Bachmeier C; Tey S; Faux S; Girgis L; Greenfield JR; Lazarus S, 2022, 'Voriconazole-Associated Periostitis: New Insights into Pathophysiology and Management', JBMR Plus, vol. 6, http://dx.doi.org/10.1002/jbm4.10557
    Journal articles | 2022
    Koay YC; Coster ACF; Chen DL; Milner B; Batarseh A; O’Sullivan JF; Greenfield JR; Samocha-Bonet D, 2022, 'Metabolomics and Lipidomics Signatures of Insulin Resistance and Abdominal Fat Depots in People Living with Obesity', Metabolites, vol. 12, http://dx.doi.org/10.3390/metabo12121272
    Journal articles | 2022
    Lasschuit JWJ; Greenfield JR; Tonks KTT, 2022, 'Contribution of peripheral neuropathy to poor bone health in the feet of people with type 2 diabetes mellitus', Acta Diabetologica, vol. 59, pp. 217 - 224, http://dx.doi.org/10.1007/s00592-021-01803-w
    Journal articles | 2022
    Patel SK; Ma CS; Bell KJ; Oram R; Hagopian WA; Fourlanos S; Greenfield JR, 2022, 'Immunophenotype and genetic risk scores to improve autoantibody negative type 1 diabetes classification: study protocol', International Journal of Clinical Trials, vol. 9, pp. 293 - 293, http://dx.doi.org/10.18203/2349-3259.ijct20222690
    Journal articles | 2022
    Raven LM; Greenfield JR; Muir CA, 2022, 'Glucagon-like Peptide-1 Receptor Agonist Treatment With Semaglutide in Type 1 Diabetes', JCEM Case Reports, vol. 1, http://dx.doi.org/10.1210/jcemcr/luac017
    Journal articles | 2022
    Raven LM; Mccormack AI; Greenfield JR, 2022, 'Letter to the Editor From Raven et al: "Three Cases of Subacute Thyroiditis Following SARS-CoV-2 Vaccine"', Journal of Clinical Endocrinology and Metabolism, vol. 107, pp. E1767 - E1768, http://dx.doi.org/10.1210/clinem/dgab822
    Journal articles | 2022
    Raven LM; Morris P; Greenfield JR, 2022, 'Hyperglycaemia induced by gamma-butyrolactone', Diabetic Medicine, vol. 39, pp. e14850, http://dx.doi.org/10.1111/dme.14850
    Journal articles | 2022
    Raven LM; Muir CA; Macdonald PS; Hayward CS; Jabbour A; Greenfield JR, 2022, 'Diabetes medication following heart transplantation: a focus on novel cardioprotective therapies—a joint review from endocrinologists and cardiologists', Acta Diabetologica, http://dx.doi.org/10.1007/s00592-022-02018-3
    Journal articles | 2022
    Sheu A; Greenfield JR; White CP; Center JR, 2022, 'Assessment and treatment of osteoporosis and fractures in type 2 diabetes', Trends in Endocrinology and Metabolism, vol. 33, pp. 333 - 344, http://dx.doi.org/10.1016/j.tem.2022.02.006
    Journal articles | 2021
    Bishay RH; Tonks KT; George J; Samocha-Bonet D; Meyerowitz-Katz G; Chisholm DJ; James DE; Greenfield JR, 2021, 'Plasma Bile Acids More Closely Align with Insulin Resistance, Visceral and Hepatic Adiposity Than Total Adiposity', Journal of Clinical Endocrinology and Metabolism, vol. 106, pp. E1131 - E1139, http://dx.doi.org/10.1210/clinem/dgaa940
    Journal articles | 2021
    Heidegger DP; Neal KE; Patel SK; Greenfield JR; Tonks KT, 2021, 'Effect of fasting ketosis and type 1 diabetes on alcohol breath analysis technology used in Australia', Internal Medicine Journal, vol. 51, pp. 1555 - 1556, http://dx.doi.org/10.1111/imj.15488
    Journal articles | 2021
    Milder TY; Stocker SL; Baysari M; Day RO; Greenfield JR, 2021, 'Prescribing of SGLT2 inhibitors in primary care: A qualitative study of General Practitioners and Endocrinologists', Diabetes Research and Clinical Practice, vol. 180, pp. 109036, http://dx.doi.org/10.1016/j.diabres.2021.109036
    Journal articles | 2021
    Patel SK; Fourlanos S; Greenfield JR, 2021, 'Comment on ‘impact of routine Clinic Measurement of random Serum c-peptide in people with a Clinician Diagnosis of type 1 diabetes’', Diabetic Medicine, vol. 38, pp. e14513, http://dx.doi.org/10.1111/dme.14513
    Journal articles | 2021
    Patel SK; Ma CS; Fourlanos S; Greenfield JR, 2021, 'Autoantibody-Negative Type 1 Diabetes: A Neglected Subtype', Trends in Endocrinology and Metabolism, vol. 32, pp. 295 - 305, http://dx.doi.org/10.1016/j.tem.2021.02.001
    Journal articles | 2021
    Perera CJ; Falasca M; Chari ST; Greenfield JR; Xu Z; Pirola RC; Wilson JS; Apte MV, 2021, 'Role of pancreatic stellate cell-derived exosomes in pancreatic cancer-related diabetes: A novel hypothesis', Cancers, vol. 13, http://dx.doi.org/10.3390/cancers13205224
    Journal articles | 2021
    Snaith JR; Samocha-Bonet D; Evans J; Liu Z; Kowalski G; Bruce C; Holmes-Walker DJ; Greenfield JR, 2021, 'Insulin resistance in type 1 diabetes managed with metformin (INTIMET): Study protocol of a double-blind placebo-controlled, randomised trial', Diabetic Medicine, vol. 38, pp. e14564, http://dx.doi.org/10.1111/dme.14564
    Journal articles | 2021
    Watt KI; Henstridge DC; Ziemann M; Sim CB; Montgomery MK; Samocha-Bonet D; Parker BL; Dodd GT; Bond ST; Salmi TM; Lee RS; Thomson RE; Hagg A; Davey JR; Qian H; Koopman R; El-Osta A; Greenfield JR; Watt MJ; Febbraio MA; Drew BG; Cox AG; Porrello ER; Harvey KF; Gregorevic P, 2021, 'Yap regulates skeletal muscle fatty acid oxidation and adiposity in metabolic disease', Nature Communications, vol. 12, pp. 2887, http://dx.doi.org/10.1038/s41467-021-23240-7
    Journal articles | 2020
    Harari A; Coster ACF; Jenkins A; Xu A; Greenfield JR; Harats D; Shaish A; Samocha-Bonet D, 2020, 'Obesity and Insulin Resistance Are Inversely Associated with Serum and Adipose Tissue Carotenoid Concentrations in Adults', Journal of Nutrition, vol. 150, pp. 38 - 46, http://dx.doi.org/10.1093/jn/nxz184
    Journal articles | 2020
    Htet TD; Godneva A; Liu Z; Chalmers E; Kolobkov D; Snaith JR; Richens R; Toth K; Danta M; Hng TM; Elinav E; Segal E; Greenfield JR; Samocha-Bonet D, 2020, 'Rationale and design of a randomised controlled trial testing the effect of personalised diet in individuals with pre-diabetes or type 2 diabetes mellitus treated with metformin', BMJ Open, vol. 10, pp. e037859, http://dx.doi.org/10.1136/bmjopen-2020-037859
    Journal articles | 2020
    Hussain I; Jin RR; Baum HBA; Greenfield JR; Devery S; Xing C; Hegele RA; Carranza-Leon BG; Linton MF; Vuitch F; Wu KHC; Precioso DR; Oshima J; Agarwal AK; Garg A, 2020, 'Multisystem progeroid syndrome with lipodystrophy, cardiomyopathy, and nephropathy due to an LMNA p.R349W variant', Journal of the Endocrine Society, vol. 4, http://dx.doi.org/10.1210/jendso/bvaa104
    Journal articles | 2020
    Lasschuit JWJ; Center JR; Greenfield JR; Tonks KTT, 2020, 'Comparison of calcaneal quantitative ultrasound and bone densitometry parameters as fracture risk predictors in type 2 diabetes mellitus', Diabetic Medicine, vol. 37, pp. 1902 - 1909, http://dx.doi.org/10.1111/dme.14183
    Journal articles | 2020
    Lasschuit JWJ; Greenfield JR; Tonks KT, 2020, 'High Risk Foot Service reduces number of Emergency Department presentations and length of stay', Diabetes and Metabolism, vol. 46, pp. 252 - 255, http://dx.doi.org/10.1016/j.diabet.2018.07.002
    Journal articles | 2020
    Martin C; Ait Boudaoud A; Poghosyan T; Zhu J; Larger E; Greenfield JR; Czernichow S; Rives-Lange C; Carette C, 2020, 'Prevalence of anti-GAD and IA2 autoantibodies in a French cohort of patients with diabetes eligible for bariatric surgery', Diabetes and Metabolism, vol. 46, pp. 407 - 409, http://dx.doi.org/10.1016/j.diabet.2019.12.004
    Journal articles | 2020
    Milder TY; Stocker SL; Day RO; Greenfield JR, 2020, 'Potential Safety Issues with Use of Sodium-Glucose Cotransporter 2 Inhibitors, Particularly in People with Type 2 Diabetes and Chronic Kidney Disease', Drug Safety, vol. 43, pp. 1211 - 1221, http://dx.doi.org/10.1007/s40264-020-01010-6
    Journal articles | 2020
    Mortimer B; Naganur VD; Satouris P; Greenfield JR; Torpy DJ; Rushworth RL, 2020, 'Acute illness in patients with concomitant Addison's disease and type 1 diabetes mellitus: Increased incidence of hypoglycaemia and adrenal crises', Clinical Endocrinology, vol. 93, pp. 104 - 110, http://dx.doi.org/10.1111/cen.14219
    Journal articles | 2020
    Muir CA; Jones GRD; Greenfield JR; Weissberger A; Samaras K, 2020, 'THYROID PEROXIDASE ANTIBODY POSITIVITY IS ASSOCIATED with RELAPSE-FREE SURVIVAL following ANTITHYROID DRUG TREATMENT for GRAVES DISEASE', Endocrine Practice, vol. 26, pp. 1026 - 1030, http://dx.doi.org/10.4158/EP-2020-0035
    Journal articles | 2020
    Smith FC; Stocker SL; Danta M; Carland JE; Kumar SS; Liu Z; Greenfield JR; Braithwaite HE; Cheng TS; Graham GG; Williams KM; Day RO, 2020, 'The safety and pharmacokinetics of metformin in patients with chronic liver disease', Alimentary Pharmacology and Therapeutics, vol. 51, pp. 565 - 575, http://dx.doi.org/10.1111/apt.15635
    Journal articles | 2020
    Snaith JR; Greenfield JR, 2020, 'COVID-19: it's changed us', Internal Medicine Journal, vol. 50, pp. 1162 - 1163, http://dx.doi.org/10.1111/imj.14968
    Journal articles | 2020
    Snaith JR; Holmes-Walker DJ; Greenfield JR, 2020, 'Letter to the editor: ⇜risk factors for cardiovascular disease (CVD) in adults with type 1 diabetes: findings from prospective real-life T1D exchange registry”', Journal of Clinical Endocrinology and Metabolism, vol. 105, pp. 1 - 2, http://dx.doi.org/10.1210/clinem/dgaa383
    Journal articles | 2020
    Snaith JR; Holmes-Walker DJ; Greenfield JR, 2020, 'Reducing Type 1 Diabetes Mortality: Role for Adjunctive Therapies?', Trends in Endocrinology and Metabolism, vol. 31, pp. 150 - 164, http://dx.doi.org/10.1016/j.tem.2019.11.007
    Journal articles | 2020
    Snaith JR; Samocha-Bonet D; Holmes-Walker DJ; Greenfield JR, 2020, 'MON-LB113 Insulin Resistance in Type 1 Diabetes Managed With Metformin (INTIMET): Rationale and Study Design of a Randomised Placebo-Controlled Trial', Journal of the Endocrine Society, vol. 4, http://dx.doi.org/10.1210/jendso/bvaa046.2038
    Journal articles | 2019
    Abdel Shaheed C; Carland JE; Graham GG; Stocker SL; Smith G; Hicks M; Williams KM; Furlong T; Macdonald P; Greenfield JR; Smith FC; Chowdhury G; Day RO, 2019, 'Is the use of metformin in patients undergoing dialysis hazardous for life? A systematic review of the safety of metformin in patients undergoing dialysis', British Journal of Clinical Pharmacology, vol. 85, pp. 2772 - 2783, http://dx.doi.org/10.1111/bcp.14107
    Journal articles | 2019
    Cehic MG; Muir CA; Greenfield JR; Hayward C; Jabbour A; Keogh A; Kotlyar E; Muthiah K; Macdonald PS, 2019, 'Efficacy and Safety of Empagliflozin in the Management of Diabetes Mellitus in Heart Transplant Recipients', Transplantation Direct, vol. 5, http://dx.doi.org/10.1097/TXD.0000000000000885
    Journal articles | 2019
    Greenfield JR; Carette C; Czernichow S, 2019, 'Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults', The New England journal of medicine, vol. 381, pp. e17, http://dx.doi.org/10.1056/NEJMc1908751
    Journal articles | 2019
    Lenders NF; Greenfield JR, 2019, 'Urinary steroid profiling in diagnostic evaluation of an unusual adrenal mass', Endocrinology, Diabetes and Metabolism Case Reports, vol. 2019, http://dx.doi.org/10.1530/EDM-19-0090
    Journal articles | 2019
    Milder TY; Stocker SL; Samocha-Bonet D; Day RO; Greenfield JR, 2019, 'Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes—cardiovascular and renal benefits in patients with chronic kidney disease', European Journal of Clinical Pharmacology, vol. 75, pp. 1481 - 1490, http://dx.doi.org/10.1007/s00228-019-02732-y
    Journal articles | 2019
    Milder TY; Stocker SL; Shaheed CA; McGrath-Cadell L; Samocha-Bonet D; Greenfield JR; Day RO, 2019, 'Combination Therapy with an SGLT2 Inhibitor as Initial Treatment for Type 2 Diabetes: A Systematic Review and Meta-Analysis', JOURNAL OF CLINICAL MEDICINE, vol. 8, http://dx.doi.org/10.3390/jcm8010045
    Journal articles | 2019
    Patel S; Chin V; Greenfield JR, 2019, 'Durvalumab-induced diabetic ketoacidosis followed by hypothyroidism', Endocrinology, Diabetes and Metabolism Case Reports, vol. 2019, http://dx.doi.org/10.1530/EDM-19-0098
    Journal articles | 2019
    Snaith JR; Holmes-Walker DJ; Greenfield JR, 2019, 'Association of insulin dose, cardiometabolic risk factors, and cardiovascular disease in type 1 diabetes during 30 years of follow-up in the DCCT/EDIC study. Diabetes care 2019;42:657-664', Diabetes Care, vol. 42, pp. E135 - E136, http://dx.doi.org/10.2337/dc19-0730
    Journal articles | 2019
    Tang A; Coster ACF; Tonks KT; Heilbronn LK; Pocock N; Purtell L; Govendir M; Blythe J; Zhang J; Xu A; Chisholm DJ; Johnson NA; Greenfield JR; Samocha-Bonet D, 2019, 'Longitudinal changes in insulin resistance in normal weight, overweight and obese individuals', Journal of Clinical Medicine, vol. 8, http://dx.doi.org/10.3390/jcm8050623
    Journal articles | 2018
    Cehic MG; Nundall N; Greenfield JR; Macdonald PS, 2018, 'Management Strategies for Posttransplant Diabetes Mellitus after Heart Transplantation: A Review', JOURNAL OF TRANSPLANTATION, vol. 2018, http://dx.doi.org/10.1155/2018/1025893
    Journal articles | 2018
    Du YT; Piscitelli D; Ahmad S; Trahair LG; Greenfield JR; Samocha-Bonet D; Rayner CK; Horowitz M; Jones KL, 2018, 'Effects of glutamine on gastric emptying of lowand high-nutrient drinks in healthy young subjects—impact on glycaemia', Nutrients, vol. 10, http://dx.doi.org/10.3390/nu10060739
    Journal articles | 2018
    Fazakerley DJ; Chaudhuri R; Yang P; Maghzal GJ; Thomas KC; Krycer JR; Humphrey SJ; Parker BL; Fisher-Wellman KH; Meoli CC; Hoffman NJ; Diskin C; Burchfield JG; Cowley MJ; Kaplan W; Modrusan Z; Kolumam G; Yang JYH; Chen DL; Samocha-Bonet D; Greenfield JR; Hoehn KL; Stocker R; James DE, 2018, 'Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance', eLife, vol. 7, http://dx.doi.org/10.7554/eLife.32111
    Journal articles | 2018
    Fazekas-Lavu M; Reyes M; Malouf M; Plit M; Havryk A; Campbell LV; Center JR; Glanville AR; Greenfield JR, 2018, 'High prevalence of diabetes before and after lung transplantation: target for improving outcome?', Internal Medicine Journal, vol. 48, pp. 916 - 924, http://dx.doi.org/10.1111/imj.13963
    Journal articles | 2018
    Isaacs M; Costin M; Bova R; Barrett HL; Heffernan D; Samaras K; Greenfield JR, 2018, 'Management of amiodarone-induced thyrotoxicosis at a cardiac transplantation centre', Frontiers in Endocrinology, vol. 9, http://dx.doi.org/10.3389/fendo.2018.00482
    Journal articles | 2018
    Ma C; Tonks KT; Center JR; Samocha-Bonet D; Greenfield JR, 2018, 'Complex interplay among adiposity, insulin resistance and bone health', Clinical Obesity, vol. 8, pp. 131 - 139, http://dx.doi.org/10.1111/cob.12240
    Journal articles | 2018
    Samocha-Bonet D; Debs S; Greenfield JR, 2018, 'Prevention and Treatment of Type 2 Diabetes: A Pathophysiological-Based Approach', Trends in Endocrinology and Metabolism, vol. 29, pp. 370 - 379, http://dx.doi.org/10.1016/j.tem.2018.03.014
    Journal articles | 2018
    Taylor JE; Campbell LV; Zhang L; Greenfield JR, 2018, 'High diabetes prevalence and insulin medication errors in hospital patients', Internal Medicine Journal, vol. 48, pp. 1529 - 1532, http://dx.doi.org/10.1111/imj.14124
    Journal articles | 2017
    Chen DLT; Brown R; Liess C; Poljak A; Xu A; Zhang J; Trenell M; Jenkins A; Chisholm D; Samocha-Bonet D; Macefield VG; Greenfield JR, 2017, 'Muscle sympathetic nerve activity is associated with liver insulin sensitivity in obese non-diabetic men', Frontiers in Physiology, vol. 8, http://dx.doi.org/10.3389/fphys.2017.00101
    Journal articles | 2017
    Isaacs M; Tonks KT; Greenfield JR, 2017, 'Euglycaemic diabetic ketoacidosis in patients using sodium-glucose co-transporter 2 inhibitors', Internal Medicine Journal, vol. 47, pp. 701 - 704, http://dx.doi.org/10.1111/imj.13442
    Journal articles | 2017
    Tonks KT; White CP; Center JR; Samocha-Bonet D; Greenfield JR, 2017, 'Bone turnover is suppressed in insulin resistance, independent of adiposity', Journal of Clinical Endocrinology and Metabolism, vol. 102, pp. 1112 - 1121, http://dx.doi.org/10.1210/jc.2016-3282
    Journal articles | 2016
    De Sousa SMC; Haghighi KS; Qiu MR; Greenfield JR; Chen DLT, 2016, 'Synchronous Nesidioblastosis, Endocrine Microadenoma, and Intraductal Papillary Mucinous Neoplasia in a Man Presenting with Hyperinsulinemic Hypoglycemia', Pancreas, vol. 45, pp. 154 - 159, http://dx.doi.org/10.1097/MPA.0000000000000430
    Journal articles | 2016
    He J; Chen DL; Samocha-Bonet D; Gillinder KR; Barclay JL; Magor GW; Perkins AC; Greenfield JR; Yang G; Whitehead JP, 2016, 'Fibroblast growth factor-1 (FGF-1) promotes adipogenesis by downregulation of carboxypeptidase A4 (CPA4)–a negative regulator of adipogenesis implicated in the modulation of local and systemic insulin sensitivity', Growth Factors, vol. 34, pp. 210 - 216, http://dx.doi.org/10.1080/08977194.2017.1285764
    Journal articles | 2016
    Lee P; Bova R; Schofield L; Bryant W; Dieckmann W; Slattery A; Govendir MA; Emmett L; Greenfield JR, 2016, 'Brown Adipose Tissue Exhibits a Glucose-Responsive Thermogenic Biorhythm in Humans', Cell Metabolism, vol. 23, pp. 602 - 609, http://dx.doi.org/10.1016/j.cmet.2016.02.007
    Journal articles | 2016
    Lee-Young RS; Hoffman NJ; Murphy KT; Henstridge DC; Samocha-Bonet D; Siebel AL; Iliades P; Zivanovic B; Hong YH; Colgan TD; Kraakman MJ; Bruce CR; Gregorevic P; McConell GK; Lynch GS; Drummond GR; Kingwell BA; Greenfield JR; Febbraio MA, 2016, 'Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle', Molecular Metabolism, vol. 5, pp. 1083 - 1091, http://dx.doi.org/10.1016/j.molmet.2016.09.002
    Journal articles | 2016
    Moon J; Kumar SS; Graham GG; Baysari MT; Williams KM; Chen W; Viardot A; Greenfield JR; Day RO, 2016, 'Trends in metformin utilisation and dose appropriateness in Australia', European Journal of Clinical Pharmacology, vol. 72, pp. 1489 - 1496, http://dx.doi.org/10.1007/s00228-016-2117-y
    Journal articles | 2016
    Tonks KT; Coster AC; Christopher MJ; Chaudhuri R; Xu A; Gagnon-Bartsch J; Chisholm DJ; James DE; Meikle PJ; Greenfield JR; Samocha-Bonet D, 2016, 'Skeletal muscle and plasma lipidomic signatures of insulin resistance and overweight/obesity in humans', Obesity, vol. 24, pp. 908 - 916, http://dx.doi.org/10.1002/oby.21448
    Journal articles | 2015
    Chaudhuri R; Khoo PS; Tonks K; Junutula JR; Kolumam G; Modrusan Z; Samocha-Bonet D; Meoli CC; Hocking S; Fazakerley DJ; Stöckli J; Hoehn KL; Greenfield JR; Yang JYH; James DE, 2015, 'Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity', npj Systems Biology and Applications, vol. 1, http://dx.doi.org/10.1038/npjsba.2015.10
    Journal articles | 2015
    Chen DL; Liess C; Poljak A; Xu A; Zhang J; Thoma C; Trenell M; Milner B; Jenkins AB; Chisholm DJ; Samocha-Bonet D; Greenfield JR, 2015, 'Phenotypic characterization of insulin-resistant and insulin-sensitive obesity', Journal of Clinical Endocrinology and Metabolism, vol. 100, pp. 4082 - 4091, http://dx.doi.org/10.1210/jc.2015-2712
    Journal articles | 2015
    Duong JK; Kumar SS; Furlong TJ; Kirkpatrick CM; Graham GG; Greenfield JR; Williams KM; Day RO, 2015, 'The pharmacokinetics of metformin and concentrations of haemoglobin A1C and lactate in Indigenous and non-Indigenous Australians with type 2 diabetes mellitus', British Journal of Clinical Pharmacology, vol. 79, pp. 617 - 623, http://dx.doi.org/10.1111/bcp.12525
    Journal articles | 2015
    Kozusko K; Tsang VHM; Bottomley W; Cho YH; Gandotra S; Mimmack M; Lim K; Isaac I; Patel S; Saudek V; O'Rahilly S; Srinivasan S; Greenfield JR; Barroso I; Campbell LV; Savage DB, 2015, 'Clinical and molecular characterization of a novel PLIN1 frameshift mutation identified in patients with familial partial lipodystrophy', Diabetes, vol. 64, pp. 299 - 310, http://dx.doi.org/10.2337/db14-0104
    Journal articles | 2015
    Lee P; Greenfield JR, 2015, 'Non-pharmacological and pharmacological strategies of brown adipose tissue recruitment in humans', Molecular and Cellular Endocrinology, vol. 418, pp. 184 - 190, http://dx.doi.org/10.1016/j.mce.2015.05.025
    Journal articles | 2015
    Lee P; Greenfield JR, 2015, 'What is the optimal bone-preserving strategy for patients with Addison's disease?', Clinical Endocrinology, vol. 83, pp. 157 - 161, http://dx.doi.org/10.1111/cen.12730
    Journal articles | 2015
    Lee P; Swarbrick MM; Greenfield JR, 2015, 'The sum of all browning in FGF21 therapeutics', Cell Metabolism, vol. 21, pp. 795 - 796, http://dx.doi.org/10.1016/j.cmet.2015.05.018
    Journal articles | 2015
    Samocha-Bonet D; Chisholm DJ; Holst JJ; Greenfield JR, 2015, 'L-glutamine and whole protein restore first-phase insulin response and increase glucagon-like peptide-1 in type 2 diabetes patients', Nutrients, vol. 7, pp. 2101 - 2108, http://dx.doi.org/10.3390/nu7042101
    Journal articles | 2015
    Sapkota S; Brien JA; Greenfield J; Aslani P, 2015, 'A systematic review of interventions addressing adherence to anti-diabetic medications in patients with type 2 diabetes - Impact on adherence', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0118296
    Journal articles | 2015
    Sapkota S; Brien JAE; Greenfield JR; Aslani P, 2015, 'A systematic review of interventions addressing adherence to anti-diabetic medications in patients with type 2 diabetes - Components of interventions', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0128626
    Journal articles | 2015
    Wiley J; Westbrook M; Long J; Greenfield JR; Day RO; Braithwaite J, 2015, 'Multidisciplinary diabetes team care: The experiences of young adults with Type 1 diabetes', Health Expectations, vol. 18, pp. 1783 - 1796, http://dx.doi.org/10.1111/hex.12170
    Journal articles | 2015
    Williams RS; Heilbronn LK; Chen DL; Coster A; Greenfield JR; Samocha-Bonet D, 2015, 'Dietary acid load, metabolic acidosis and insulin resistance - Lessons from cross-sectional and overfeeding studies in humans', Clinical Nutrition, vol. 35, pp. 1084 - 1090, http://dx.doi.org/10.1016/j.clnu.2015.08.002
    Journal articles | 2014
    Meretoja A; Churilov L; Campbell BCV; Aviv RI; Yassi N; Barras C; Mitchell P; Yan B; Nandurkar H; Bladin C; Wijeratne T; Spratt NJ; Jannes J; Sturm J; Rupasinghe J; Zavala J; Lee A; Kleinig T; Markus R; Delcourt C; Mahant N; Parsons MW; Levi C; Anderson CS; Donnan GA; Davis SM, 2014, 'The Spot sign and Tranexamic acid On Preventing ICH growth - AUStralasia Trial (STOP-AUST): Protocol of a phase II randomized, placebo-controlled, double-blind, multicenter trial', International Journal of Stroke, vol. 9, pp. 519 - 524, http://dx.doi.org/10.1111/ijs.12132
    Journal articles | 2014
    Samocha-Bonet D; Chisholm DJ; Gribble FM; Coster ACF; Carpenter KH; Jones GRD; Holst JJ; Greenfield JR, 2014, 'Glycemic effects and safety of L-glutamine supplementation with or without sitagliptin in type 2 diabetes patients-a randomized study', PLoS ONE, vol. 9, http://dx.doi.org/10.1371/journal.pone.0113366
    Journal articles | 2014
    Tang A; Milner KL; Tonks K; Campbell LV; Greenfield JR, 2014, 'Comment on Brethauer et al. Bariatric surgery improves the metabolic profile of morbidly obese patients with type 1 diabetes. Diabetes Care 2014;37:e51-e52', Diabetes Care, vol. 37, pp. e248 - e249, http://dx.doi.org/10.2337/dc14-0578
    Journal articles | 2014
    Wiley J; Westbrook M; Greenfield JR; Day RO; Braithwaite J, 2014, 'Shared decision-making: The perspectives of young adults with type I diabetes mellitus', Patient Preference and Adherence, vol. 8, pp. 423 - 435, http://dx.doi.org/10.2147/PPA.S57707
    Journal articles | 2014
    Wiley J; Westbrook M; Long J; Greenfield JR; Day RO; Braithwaite J, 2014, 'Diabetes Education: the Experiences of Young Adults with Type 1 Diabetes', Diabetes Therapy, vol. 5, pp. 299 - 321, http://dx.doi.org/10.1007/s13300-014-0056-0
    Journal articles | 2013
    Chang J; Wu T; Greenfield JR; Samocha-Bonet D; Horowitz M; Rayner CK, 2013, 'Effects of Intraduodenal Glutamine on Incretin Hormone and Insulin Release, the Glycemic Response to an Intraduodenal Glucose Infusion, and Antropyloroduodenal Motility in Health and Type 2 Diabetes', Diabetes Care, vol. 36, pp. 2262 - 2265, http://dx.doi.org/10.2337/dc12-1663
    Journal articles | 2013
    Gifford G; Milliken S; Greenfield J, 2013, 'Diabetic ketoacidosis secondary to L-asparaginase in acute lymphoblastic leukaemia', Internal Medicine Journal, vol. 43, pp. 946 - 948, http://dx.doi.org/10.1111/imj.12216
    Journal articles | 2013
    Heilbronn LK; Coster ACF; Campbell LV; Greenfield JR; Lange K; Christopher MJ; Meikle PJ; Samocha-Bonet D, 2013, 'The effect of short-term overfeeding on serum lipids in healthy humans', Obesity, vol. 21, http://dx.doi.org/10.1002/oby.20508
    Journal articles | 2013
    Hocking S; Samocha-Bonet D; Milner KL; Greenfield JR; Chisholm DJ, 2013, 'Adiposity and insulin resistance in humans: The role of the different tissue and cellular lipid depots', Endocrine Reviews, vol. 34, pp. 463 - 500, http://dx.doi.org/10.1210/er.2012-1041
    Journal articles | 2013
    Jenkins AB; Batterham M; Samocha-Bonet D; Tonks K; Greenfield JR; Campbell LV, 2013, 'Segregation of a Latent High Adiposity Phenotype in Families with a History of Type 2 Diabetes Mellitus Implicates Rare Obesity-Susceptibility Genetic Variants with Large Effects in Diabetes-Related Obesity', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0070435
    Journal articles | 2013
    Lee P; Day RO; Greenfield JR; Ho KK, 2013, 'Formoterol, a highly selective beta 2-selective agonist, increases energy expenditure and fat utilisation in men', International journal of obesity, vol. 37, pp. 593 - 597, http://dx.doi.org/10.1038/ijo.2012.90
    Journal articles | 2013
    Petersons CJ; Mangelsdorf BL; Jenkins AB; Poljak A; Smith MD; Greenfield JR; Thompson CH; Burt MG, 2013, 'Effects of low-dose prednisolone on hepatic and peripheral insulin sensitivity, insulin secretion, and abdominal adiposity in patients with inflammatory rheumatologic disease', Diabetes Care, vol. 36, pp. 2822 - 2829, http://dx.doi.org/10.2337/dc12-2617
    Journal articles | 2013
    Tonks KT; Ng Y; Miller S; Coster ACF; Samocha-Bonet D; Iseli TJ; Xu A; Patrick E; Yang JYH; Junutula JR; Modrusan Z; Kolumam G; Stöckli J; Chisholm DJ; James DE; Greenfield JR, 2013, 'Impaired Akt phosphorylation in insulin-resistant human muscle is accompanied by selective and heterogeneous downstream defects', Diabetologia, vol. 56, pp. 875 - 885, http://dx.doi.org/10.1007/s00125-012-2811-y
    Journal articles | 2013
    Wiley J; Westbrook M; Long J; Greenfield JR; Day RO; Braithwaite J, 2013, 'Multidisciplinary diabetes team care: The experiences of young adults with Type 1 diabetes', Health Expectations, http://dx.doi.org/10.1111/hex.12170
    Journal articles | 2012
    Duong JK; Roberts DM; Furlong TJ; Kumar SS; Greenfield JR; Kirkpatrick CM; Graham GG; Williams KM; Day RO, 2012, 'Metformin therapy in patients with chronic kidney disease', Diabetes Obesity and Metabolism, vol. 14, pp. 963 - 965, http://dx.doi.org/10.1111/j.1463-1326.2012.01617.x
    Journal articles | 2012
    Lee P; Greenfield JR; Gilbert K; Campbell LV, 2012, 'Recreational drug use in type 1 diabetes: An invisible accomplice to poor glycaemic control?', Internal Medicine Journal, vol. 42, pp. 198 - 202, http://dx.doi.org/10.1111/j.1445-5994.2011.02653.x
    Journal articles | 2012
    Samocha-Bonet D; Campbell LV; Mori TA; Croft KD; Greenfield JR; Turner N; Heilbronn LK, 2012, 'Overfeeding reduces insulin sensitivity and increases oxidative stress, without altering markers of mitochondrial content and function in humans', PLoS One, vol. 7, pp. e36320, http://dx.doi.org/10.1371/journal.pone.0036320
    Journal articles | 2012
    Samocha-Bonet D; Chisholm DJ; Tonks K; Campbell LV; Greenfield JR, 2012, 'Insulin-sensitive obesity in humans - a 'favorable fat' phenotype?', Trends Endocrinol Metab, vol. 23, pp. 116 - 124, http://dx.doi.org/10.1016/j.tem.2011.12.005
    Journal articles | 2011
    Graham GG; Punt J; Manit A; Day RO; Doogue MP; Duong JK; Furlong TJ; Greenfield JR; Greenup L; Carl m kirkpatrick CM; Ray J; Timmins P; Williams KM, 2011, 'Clinical pharmacokinetics of metforim', Clinical Pharmacokinetics, vol. 50, pp. 81 - 98, http://dx.doi.org/10.2165/11534750-000000000-00000
    Journal articles | 2011
    Greenfield JR, 2011, 'Melanocortin signalling and the regulation of blood pressure in human obesity', Journal of Neuroendocrinology, vol. 23, pp. 186 - 193, http://dx.doi.org/10.1111/j.1365-2826.2010.02088.x
    Journal articles | 2011
    Lee P; Ho KK; Greenfield JR, 2011, 'Hot fat in a cool man: infrared thermography and brown adipose tissue', Diabetes Obesity and Metabolism, vol. 13, pp. 92 - 93, http://dx.doi.org/10.1111/j.1463-1326.2010.01318.x
    Journal articles | 2011
    Lee P; Kengne A; Greenfield JR; Day RO; Chalmers J; Ho KK, 2011, 'Metabolic sequelae of beta-blocker theraphy: weighing in on the obesity epidemic?', International journal of obesity, vol. 35, pp. 1395 - 1403, http://dx.doi.org/10.1038/ijo.2010.284
    Journal articles | 2011
    Lee P; Zhao JT; Swarbrick MM; Gracie G; Bova RJ; Greenfield JR; Freund J; Ho KK, 2011, 'High prevalence of brown adipose tissue in adult humans', Journal of Clinical Endocrinology and Metabolism, vol. 96, pp. 2450 - 2455, http://dx.doi.org/10.1210/jc.2011-0487
    Journal articles | 2011
    Martinelli CE; Keogh JM; Greenfield JR; Henning L; Van der klaauw A; Blackwood D; O''Rahilly S; Roelfsema F; Camacho M; Pijl H; Farooqi S, 2011, 'Obesity due to Melanocortin 4 Receptor (MC4R) deficiency is associated with increased linear growth and final height, fasting, hyperinsulinemia, and incompletely suppressed Growth Hormone secretion', Journal of Clinical Endocrinology and Metabolism, vol. 96, pp. E181 - E188, http://dx.doi.org/10.1210/jc.2010-1369
    Journal articles | 2011
    Samocha-Bonet D; Wong O; Synnott EL; Piyaratna N; Douglas A; Gribble FM; Holst JJ; Chisholm DJ; Greenfield JR, 2011, 'Glutamine reduces postprandial glycemia and augments the glucagon-like peptide-1 response in type 2 diabetes patients', J Nutr, vol. 141, pp. 1233 - 1238, http://dx.doi.org/10.3945/jn.111.139824
    Journal articles | 2010
    Czernichow S; Greenfield JR; Galan P; Bastard JP; Charnaux N; Samaras K; Safar M; Blacher J; Hercberg S; Levi BI, 2010, 'Microvascular dysfunction in healthy insulin-sensitive overweight individuals', Journal of Hypertension, vol. 28, pp. 325 - 332, http://dx.doi.org/10.1097/HJH.0b013e328333d1fc
    Journal articles | 2010
    Czernichow S; Greenfield JR; Galan P; Jellouli F; Safar M; Blacher J; Hercberg S; Levi BI, 2010, 'Macrovascular and microvascular dysfunction in the metabolic syndrome', Hypertension Research, vol. 33, pp. 293 - 297, http://dx.doi.org/10.1038/hr.2009.228
    Journal articles | 2010
    Czernichow S; Lee C; Barzi F; Greenfield JR; Baur LA; Chalmers J; Woodward M; Huxley R, 2010, 'Efficacy of weight loss drugs on obesity and cardiovascular risk factors in obese adolescents: a meta-analysis of randomized controlled trials', Obesity Reviews, vol. 11, pp. 150 - 158, http://dx.doi.org/10.1111/j.1467-789X.2009.00620.x
    Journal articles | 2010
    Lee P; Greenfield JR; Ho KK; Fulham MJ, 2010, 'A critical appraisal of prevalence and metabolic signifigance of brown adipose tissue in adult humans', American Journal of Physiology - Endocrinology and Metabolism, vol. 299, pp. E601 - E606, http://dx.doi.org/10.1152/ajpendo.00298.2010
    Journal articles | 2010
    Tam CS; Viardot A; Clement K; Tordjman J; Tonks K; Greenfield JR; Campbell LV; Samocha-Bonet D; Heilbronn LK, 2010, 'Short-term overfeeding may induce peripheral insulin resistance without altering subcutaneous adipose tissue macrophages in humans', Diabetes, vol. 59, pp. 2164 - 2170, http://dx.doi.org/10.2337/db10-0162
    Journal articles | 2009
    Greenfield JR; Farooqi IS; Keogh JM; Henning E; Habib AM; Blackwood A; Reimann F; Holst JJ; Gribble FM, 2009, 'Oral glutamine increases circulating glucagon-like peptide 1, glucagon, and insulin concentrations in lean, obese, and type 2 diabetic subjects', American Journal of Clinical Nutrition, vol. 89, pp. 106 - 113, http://dx.doi.org/10.3945/ajcn.2008.26362
    Journal articles | 2009
    Lee P; Greenfield JR; Campbell LV, 2009, 'Managing young people with Type 1 diabetes in a `rave` new world: Metabolic complications of substance abuse in Type 1 diabetes', Diabetic Medicine, vol. 26, pp. 328 - 333, http://dx.doi.org/10.1111/j.1464-5491.2009.02678.x
    Journal articles | 2009
    Lee P; Greenfield JR; Campbell LV, 2009, 'Vitamin D insufficiency - a novel mechanism of statin-induced myalgia?', Clinical Endocrinology, vol. 71, pp. 154 - 155, http://dx.doi.org/10.1111/j.1365-2265.2008.03448.x
    Journal articles | 2009
    Lee P; Greenfield JR; Ho K, 2009, 'Factors determining inadequate hypoglycaemia during insulin tolerance testing (ITT) after pituitary surgery', Clinical Endocrinology, vol. 71, pp. 82 - 85, http://dx.doi.org/10.1111/j.1365-2265.2008.03466.x
    Journal articles | 2009
    Lee P; Greenfield JR; Seibel MJ; Eisman JA; Center JR, 2009, 'Adequacy of Vitamin D Replacement in Severe Deficiency Is Dependent on Body Mass Index', American Journal of Medicine, vol. 122, pp. 1056 - 1060, http://dx.doi.org/10.1016/j.amjmed.2009.06.008
    Journal articles | 2008
    Lloret-Linares C; Greenfield JR; Czernichow S, 2008, 'Effect of weight-reducing agents on glycaemic parameters and progression to Type 2 diabetes: a review', Diabetic Medicine, vol. 25, pp. 1142 - 1150, http://dx.doi.org/10.1111/j.1464-5491.2008.02550.x
    Journal articles | 2008
    Wong LY; Moore J; Hill D; Brenner P; Delprado W; Turner J; Taylor J; Campbell L; Greenfield JR, 2008, 'Custing's syndrome can precipitate diabetes but mask non-Hodgkin's lymphoma', Medical Journal of Australia, vol. 188, pp. 262, http://dx.doi.org/10.5694/j.1326-5377.2008.tb01608.x
    Journal articles | 2008
    Wong LY; Moore JJ; Hill D; Brenner PC; Delprado W; Turner J; Taylor J; Campbell L; Greenfield JR, 2008, 'Cushing`s syndrome can precipitate diabetes but mask non-Hodgkin`s lymphoma', Medical Journal of Australia, vol. 188, pp. 262 - 262, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255914800025&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Journal articles | 2006
    Bryant W; Greenfield JR; Chisholm DJ; Campbell LV, 2006, 'Diabetes Guidelines: easier to preach than to practice?', Medical Journal of Australia, vol. 185, pp. 305 - 309, https://www.ncbi.nlm.nih.gov/pubmed/16999670
    Journal articles | 2006
    Greenfield JR; Campbell LV, 2006, 'Relationship between inflammation, insulin resistance and type 2 diabetes: 'Cause or effect'?', Current Diabetes Reviews, vol. 2, pp. 195 - 211, http://dx.doi.org/10.2174/157339906776818532
    Journal articles | 2006
    Greenfield JR; Samaras K, 2006, 'Evaluation of pituitary function in the fatigued patient: a review of 59 cases', European Journal of Endocrinology, vol. 154, pp. 147 - 157, http://dx.doi.org/10.1530/eje.1.02010
    Journal articles | 2006
    Greenfield JR; Samaras K, 2006, 'Suppression of HPA axis in adults taking inhaled corticosteroids', Thorax, vol. 61, pp. 272 - 273, http://dx.doi.org/10.1136/thx.2005.049643
    Journal articles | 2006
    Greenfield JR; Samaras K; Chisholm DJ; Campbell LV, 2006, 'Effect of postprandial insulinemia and insulin resistance on measurement of arterial stiffness (augmentation index)', International Journal of Cardiology, vol. 114, pp. 50 - 56, http://dx.doi.org/10.1016/j.ijcard.2005.12.007
    Journal articles | 2006
    Meier C; Meinhardt U; Greenfield JR; de Winter J; Nguyen TV; Dunstan C; Seibel MJ, 2006, 'Serum cathepsin K concentrations reflect osteoclastic activity in women with postmenopausal osteoporosis and patients with Paget`s disease', Clinical Laboratory, vol. 52, pp. 1 - 10
    Journal articles | 2005
    Greenfield JR; Samaras K; Hayward CS; Chisholm DJ; Campbell LV, 2005, 'Beneficial postprandial effect of a small amount of alcohol on diabetesand cardiovascular risk factors: Modification by insulin resistance', Journal of Clinical Endocrinology and Metabolism, vol. 90, pp. 661 - 672, http://dx.doi.org/10.1210/jc.2004-1511
    Journal articles | 2004
    Greenfield JR; Campbell LV, 2004, 'Insulin resistance and obesity', Clinics in Dermatology, vol. 22, pp. 289 - 295, http://dx.doi.org/10.1016/j.clindermatol.2004.01.011
    Journal articles | 2004
    Greenfield JR; Chisholm DJ, 2004, 'Thiazolidinediones - Mechanisms of action', Australian Prescriber, vol. 27, pp. 67 - 70+79, http://dx.doi.org/10.18773/austprescr.2004.059
    Journal articles | 2004
    Greenfield JR; Samaras K; Jenkins AB; Kelly PJ; Spector TD; Campbell LV, 2004, 'Do gene-environment interactions influence fasting plasma lipids? Astudy of twins', European Journal of Clinical Investigation, vol. 34, pp. 590 - 598, http://dx.doi.org/10.1111/j.1365-2362.2004.01389.x
    Journal articles | 2004
    Greenfield JR; Samaras K; Jenkins AB; Kelly PJ; Spector TD; Gallimore J; Pepys M; Campbell LV, 2004, 'Obesity is an important determinant of baseline serum C-reactiveprotein concentration in monozygotic twins, independent of geneticinfluences', Circulation, vol. 109, pp. 3022 - 3028, http://dx.doi.org/10.1161/01.CIR.0000130640.77501.79
    Journal articles | 2004
    Kriketos AD; Greenfield JR; Peake PW; Furler SM; Denyer GS; Charlesworth JA; Campbell LV, 2004, 'Inflammation, Insulin Resistance, and Adiposity: A study of first-degree relatives of type 2 diabetic subjects', Diabetes Care, vol. 27, pp. 2033 - 2040, http://dx.doi.org/10.2337/diacare.27.8.2033
    Journal articles | 2003
    Greenfield JR; Samaras K; Campbell LV; Spector TD; Hayward CS; Jenkins AB; Kelly PJ, 2003, 'Physical activity reduces genetic susceptibility to increased central systolic pressure augmentation: a study of female twins', Journal of the American College of Cardiology, vol. 42, pp. 264 - 270, http://dx.doi.org/10.1016/S0735-1097(03)00631-4
    Journal articles | 2003
    Greenfield JR; Samaras K; Jenkins AB; Kelly PJ; Spector TD; Campbell LV, 2003, 'Moderate alcohol consumption, estrogen replacement therapy, and physical activity are associated with increased insulin sensitivity: Is abdominal adiposity the mediator?', Diabetes Care, vol. 26, pp. 2734 - 2740, http://dx.doi.org/10.2337/diacare.26.10.2734
    Journal articles | 2003
    Greenfield JR; Samaras K; Spector TD; Campbell LV; Jenkins AB; Kelly PJ, 2003, 'Moderate Alcohol Consumption, Dietary Fat Composition, and Abdominal Obesity in Women: Evidence of Gene-Environment Interaction', Journal of Clinical Endocrinology and Metabolism, vol. 88, pp. 5381 - 5386, http://dx.doi.org/10.1210/jc.2003-030851
    Journal articles | 2002
    Greenfield JR; Samaras K; Chisholm DJ, 2002, 'Insulin resistance, intra-abdominal fat, cardiovascular risk factors, and androgens in healthy young women with type 1 diabetes mellitus', Journal of Clinical Endocrinology and Metabolism, vol. 87, pp. 1036 - 1040, http://dx.doi.org/10.1210/jcem.87.3.8324
    Journal articles | 2002
    Greenfield JR; Samaras K; Chisholm DJ; Campbell LV, 2002, 'Regional intra-subject variability in abdominal adiposity limits usefulness of computed tomography', Obesity Research, vol. 10, pp. 260 - 265, http://dx.doi.org/10.1038/oby.2002.35
    Journal articles | 2001
    Greenfield JR; Center JR; Freund J; Eisman JA, 2001, 'Treatment of an Atraumatic Fracture: The importance of establishing a definitive diagnosis.', Journal of Bone and Mineral Research, vol. 16, pp. 2362 - 2364, http://dx.doi.org/10.1359/jbmr.2001.16.12.2362
  • Reports | 2016
    Shrosbree J; Pokorny A; Stone E; Epstein R; Mccormack A; Greenfield JR, 2016, Ectopic Cushing syndrome due to neuroendocrine prostatic cancer, http://dx.doi.org/10.1111/imj.13063
    Reports | 2013
    Greenfield JR; Chisholm DJ, 2013, How Sweet It Is: Intestinal Sweet Taste Receptors in Type 2 Diabetes, http://dx.doi.org/10.2337/db13-1018

2023    Raven L and Greenfield JR. A phase 2, randomised, placebo-controlled trial of SGLT2 inhibition with empagliflozin on metabolic, renal and cardiac transplant recipients. Australian Diabetes Research Grant: $20,000.

2022    Humphreys S, James D, Greenfield JR (CIC), Wojtaszewski J. Mapping the beneficial effects of exercise in humans using personalised phosphoproteomics. NHMRC Ideas Grant, APP2011083: $1,348,941.

2022   Greenfield JR, Jabbour A, Hayward A, MacDonald P, Raven L Muir C. A phase 2, randomised, placebo-controlled trial of SGLT2 inhibition with empagliflozin on metabolic,renal and cardiac transplant patients. St. Vincent’s Clinic Foundation Sr Mary Bernice Packer Family Foundation Research Grant: $120,000.

2022   Perera C, Minoti A, Zhihong X, Falasca M, Goldstein D, Greenfield JR (CI5), Hardikar A. Innovation Grant: Early Detection with a focus on Rural and Regional areas. TheAustralian Pancreatic Cancer Foundation: $99,895.

2021    Greenfield JR, Patel S, Fourlanos S, Grey S, Phan T, Ma C. Elucidating the immune and metabolic phenotype of autoantibody negative diabetes in adults. St. Vincent’s Clinic Foundation Sr Mary Bernice Packer Family Foundation Research Grant: $120,000.

2020   Greenfield JR, Snaith J, Samocha-Bonet D, Holmes-Walker J, Girgis C. INTIMET INsulin resistance in Type 1 diabetes managed with METformin. St. Vincent’s Clinic Foundation Tancred Research Grant: $50,000.

2020    Apte M, Perera C, Chari S, Greenfield JR (CID), Xu Z, Wilson J, Pirola R. Pancreatic Cancer-Related Diabetes: Novel Role of Pancreatic Stellate Cells. NHMRC Ideas Grant, APP1185751: $486, 000.

2019   Greenfield JR, Snaith J, Holmes-Walker J, Girgis C, Samocha-Bonet. Phenotypic Characterisation of Insulin-Sensitive and Insulin-Resistant Adults with Type 1 Diabetes. Diabetes Australia Research Trust Millennium Grant (Type 1):  $150,000.

2019    Liu G, Morris M, Craig M, Greenfield JR, Vranes P. Smart point-of-care paper test strips towards prevention of type 2 diabetes. Biomedical Engineering Seed Fund, UNSW: $45,0817.

2019     Day R, Greenfield JR, Sevastos J, Stocker S, Samocha-Bonet D, Milder T. Vascular effects of the sodium-glucose cotransporter 2 inhibitor empagliflozin in people with type 2 diabetes and chronic kidney disease. St Vincent’s Clinic Foundation SVPHS Ladies’ Committee Sister Mary Bernice Research Grant: $120,000.

2018    Greenfield JR, Samocha-Bonet D. Personalised Medicine in Prediabetes – Towards Preventing Diabetes in Individuals at Risk. St Vincent’s Clinic Foundation SVPHS Ladies’ Committee Sister Mary Bernice Research Grant: $100,000.

2017   Gregory L, Taylor J, Greenfield JR. Introducing a Dose Adjustment For Normal Eating program for type 1 diabetes. 2017 St Vincent’s Clinic Foundation Research Grant: $30,000.

2017  Day R, Macdonald P, Greenfield JR, Graham G, Stocker S, Carland J. The safety and pharmacokinetics of metformin in heart failure. 2017 St Vincent’s Clinic FoundationResearch Grant: $30,000.

2017   Day R, Carland JE, Stocker SL, Norris RLG, Greenfield JR. UNSW Research Infrastructure Scheme 2017: Supporting Collaborative Research. Installation of a Shimadzu Nexera X2 UHPLC in the Depart of Clinical Pharmacology: $78,431.

2016    Samocha-Bonet D, Greenfield JR. Body acid/base balance and insulin resistance in obesity. Diabetes Australia Research Trust: $60,000.

2016    Greenfield JR, Center JR. St. Vincent’s Clinic Foundation Tancred Research Grant: $50,000

2014    Greenfield JR, Samocha-Bonet D. Insulin-sensitive obesity: is it a sustained phenotype? Anonymous* Research Foundation (*at request of Foundation): $380,000

2013    Samocha-Bonet D, Greenfield JR, Meikle PJ, Coster ACF, Tonks K. The role of sphingolipids in insulin resistance - a follow up study in humans. Diabetes Australia Research Trust: $60,000

2012    McCormack AI, Greenfield JR. St. Vincent’s Clinic Foundation Tancred Grant: Insulin signalling pathway in cancer tissue of insulin-resistant, insulin-sensitive and type 2 diabetic humans: $66,000

2011    Greenfield JR, Swarbrick M, Lee P, Freund J, Macefield V, Dawood T. Is MC4R deficiency associated with alterations in sympathetic nervous system and brown adipose tissue activity in humans? St. Vincent’s Clinic Annual grant: $30,000

2010   Burt M, Greenfield JR, Slavotinek J, Thompson. Effect of acute and chronic glucocorticoids on carbohydrate metabolism in elderly subjects. Diabetes Australia Research Trust: $58,290

2010     Ho K, Lee P, Greenfield JR, Freund J, Bova R. Significance of brown fat in humans. St. Vincent’s Clinic Annual grant: $30,000

2010    Greenfield JR, Samoch-Bonet D, Campbell LV. St. Vincent’s Clinic Annual grant: $30,000.

2009    Greenfield JR (New Investigator, sole CIA), NHMRC Project Grant. Effect of oral glutamine on GLP-1 and insulin secretion and glycaemia in humans: $382,500

2009    Day RO, Kirkpatrick CM, Williams KM, Greenfield JR, Giacomini K, ARC Linkage Grant. $195,214

2008    James DJ, Greenfield JR. Diabetes Australia Millennium Grant (Type 2): Defining the insulin-signalling defect in human insulin resistance and type 2 diabetes: $150,000

2008    Greenfield JR, James DJ, Chisholm DJ. St. Vincent’s Clinic Foundation Tancred Grant: $50,000

2008    Greenfield JR, Samocha-Bonet D, Viardot A, Campbell LV. Pfizer Neuro Science Grant: $50,000

2008    Greenfield JR. Diabetes Australia Research Trust: $50,000 

2005    Greenfield JR. RACP Servier Cardiovascular Metabolic Fellowship: $20,000

2005    Greenfield JR. St. Vincent’s Clinic Foundation Travelling Fellowship: $10,000

2004    Greenfield JR, Chisholm DJ, Campbell LV. Cardiovascular Lipid Research Grant: $40,000

2001    Greenfield JR. NHMRC Travelling Award for Research Training Scholarship #209658: $10,000

2001    Greenfield JR. NHMRC Medical/Dental Award for Research Training (PhD) #152502

1999    Greenfield JR. Chisholm DJ. RT Hall Trust Grant

Select awards:

2020    University of NSW 2020 Arc Postgraduate Council Research Supervisor Award

2017    Ranji and Amara Wikramanayake Clinical Diabetes Award, Australia Diabetes Society 

2010    Don Chisholm Fellowship, Garvan Institute of Medical Research

2005    PhD Thesis Prize, Garvan Institute of Medical Research

1989-94 Inaugural Alumni Association Scholarship, University of New South Wales


 

Fields of research:  Diabetes, Obesity, Metabolism

Research interests: 

Our recent discoveries have identified a group of overweight and obese humans who appear to be at lower risk of diabetes and heart disease than other obese individuals. A major focus of our laboratory is to establish the factors that confer this metabolic protection and to devise a set of clinical criteria that will assist in their identification in clinical practice. The outcome of this research will expand our knowledge regarding the relative importance of metabolic abnormalities, such as abdominal and liver fat, on the development of insulin resistance and diabetes. We will find out what protects the overweight and obese people and whether they remain at lower risk of metabolic disease over long periods of time.

Another focus of our group is the identification of specific genetic defects that cause diabetes and obesity in humans. The conditions we are studying are monogenic or single-gene obesity disorders (including melanocortin 4 deficiency), lipodystrophies (partial and generalised) and monogenic diabetes (previously known as MODY - Maturity Onset Diabetes of the Young). Major improvement in insulin resistance after bariatric surgery in a lipodystrophy due to a novel gene has just been reported for the first time.

Other studies have established the effects of glutamine, an amino acid, on metabolism, both in isolation and in combination with a new diabetes medication. Glutamine appears to have a promising effect on glucose lowering in the post-meal state and may offer a simple, novel and effective treatment in type 2 diabetes. We are studying the effects on an alkaline diet on insulin sensitivity in humans, to determine whether there is any scientific evidence that this approach improves metabolic health.

We have undertaken collaborative studies with the Department of Clinical Pharmacology at St Vincent's Hospital to study the effects of metformin, particularly in relation to specific genetic variations in humans.

Our current focus is on investigating the potential benefits of type 2 diabetes medications (SGLT-2 inhibitors and GLP-1 receptor agonists) in individuals with type 1 diabetes, in order to reduce morbidity and cardiovascular mortality.