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Dr Joshua Hamey
Postdoctoral Fellow

Dr Joshua Hamey

Science
School of Biotech & Biomolecular Science

Joshua Hamey is a post-doctoral Research Associate in the School of Biotechnology and Biomolecular Sciences in the group of Professor Marc Wilkins. His research focuses on understanding proteins and their post-translational modifications, particularly through use of mass spectrometry.
E-mail
j.hamey@unsw.edu.au
  • Journal articles | 2022
    2022, 'Differential Proteome and Interactome Analysis Reveal the Basis of Pleiotropy Associated With the Histidine Methyltransferase Hpm1p', Molecular and Cellular Proteomics, 21, http://dx.doi.org/10.1016/j.mcpro.2022.100249
    Journal articles | 2022
    2022, 'Identification of Protein Isoforms Using Reference Databases Built from Long and Short Read RNA-Sequencing', Journal of Proteome Research, 21, pp. 1628 - 1639, http://dx.doi.org/10.1021/acs.jproteome.1c00968
    Journal articles | 2022
    2022, 'Site-specific Phosphorylation of Histone H3K36 Methyltransferase Set2p and Demethylase Jhd1p is Required for Stress Responses in Saccharomyces cerevisiae', Journal of Molecular Biology, 434, pp. 167500, http://dx.doi.org/10.1016/j.jmb.2022.167500
    Journal articles | 2021
    2021, 'Discovery of Arginine Methylation, Phosphorylation, and Their Co-occurrence in Condensate-Associated Proteins in Saccharomyces cerevisiae', Journal of Proteome Research, 20, pp. 2420 - 2434, http://dx.doi.org/10.1021/acs.jproteome.0c00927
    Journal articles | 2021
    2021, 'Eukaryote-conserved histone post-translational modification landscape in Giardia duodenalis revealed by mass spectrometry', International Journal for Parasitology, 51, pp. 225 - 239, http://dx.doi.org/10.1016/j.ijpara.2020.09.006
    Journal articles | 2021
    2021, 'Post-translational modification analysis of Saccharomyces cerevisiae histone methylation enzymes reveals phosphorylation sites of regulatory potential', Journal of Biological Chemistry, 296, http://dx.doi.org/10.1074/JBC.RA120.015995
    Journal articles | 2021
    2021, 'Systematic investigation of PRMT6 substrate recognition reveals broad specificity with a preference for an RG motif or basic and bulky residues', FEBS Journal, 288, pp. 5668 - 5691, http://dx.doi.org/10.1111/febs.15837
    Journal articles | 2020
    2020, 'Analytical Guidelines for co-fractionation Mass Spectrometry Obtained through Global Profiling of Gold Standard Saccharomyces cerevisiae Protein Complexes', Molecular and Cellular Proteomics, 19, pp. 1876 - 1895, http://dx.doi.org/10.1074/mcp.RA120.002154
    Journal articles | 2020
    2020, 'Cross-linking Mass Spectrometry Analysis of the Yeast Nucleus Reveals Extensive Protein-Protein Interactions Not Detected by Systematic Two-Hybrid or Affinity Purification-Mass Spectrometry', Analytical Chemistry, 92, pp. 1874 - 1882, http://dx.doi.org/10.1021/acs.analchem.9b03975
    Journal articles | 2020
    2020, 'Crosstalk of Phosphorylation and Arginine Methylation in Disordered SRGG Repeats of Saccharomyces cerevisiae Fibrillarin and Its Association with Nucleolar Localization', Journal of Molecular Biology, 432, pp. 448 - 466, http://dx.doi.org/10.1016/j.jmb.2019.11.006
    Journal articles | 2020
    2020, 'Eukaryote-conserved methylarginine is absent in diplomonads and functionally compensated in Giardia', Molecular Biology and Evolution, 37, pp. 3525 - 3549, http://dx.doi.org/10.1093/molbev/msaa186
    Journal articles | 2020
    2020, 'Post-translational modification analysis of Saccharomyces cerevisiae histone methylation enzymes reveals phosphorylation sites of regulatory potential.', J Biol Chem, pp. 100192, http://dx.doi.org/10.1074/jbc.RA120.015995
    Journal articles | 2019
    2019, 'Histone H3 mutations: An updated view of their role in chromatin deregulation and cancer', Cancers, 11, pp. 1 - 24, http://dx.doi.org/10.3390/cancers11050660
    Journal articles | 2019
    2019, 'MS2-Deisotoper: A Tool for Deisotoping High-Resolution MS/MS Spectra in Normal and Heavy Isotope-Labelled Samples', Proteomics, 19, http://dx.doi.org/10.1002/pmic.201800444
    Journal articles | 2018
    Hamey JJ; Wilkins MR, 2018, 'Methylation of Elongation Factor 1A: Where, Who, and Why?', Trends in Biochemical Sciences, 43, pp. 211 - 223, http://dx.doi.org/10.1016/j.tibs.2018.01.004
    Journal articles | 2018
    2018, 'Knockout of the Hmt1p arginine methyltransferase in saccharomyces cerevisiae leads to the dysregulation of phosphate-associated genes and processes', Molecular and Cellular Proteomics, 17, pp. 2462 - 2479, http://dx.doi.org/10.1074/mcp.RA117.000214
    Journal articles | 2018
    2018, 'MT-MAMS: Protein Methyltransferase Motif Analysis by Mass Spectrometry', Journal of Proteome Research, 17, pp. 3485 - 3491, http://dx.doi.org/10.1021/acs.jproteome.8b00396
    Journal articles | 2017
    Hamey JJ; Wienert B; Quinlan KG R; Wilkins MR, 2017, 'METTL21B Is a Novel Human lysine methyltransferase of translation elongation factor 1A: Discovery by CRISPR/Cas9 Knockout', Molecular and Cellular Proteomics, 16, pp. 2229 - 2242, http://dx.doi.org/10.1074/mcp.M116.066308
    Journal articles | 2016
    Hamey JJ; Hart-Smith G; Erce MA; Wilkins MR, 2016, 'The activity of a yeast Family 16 methyltransferase, Efm2, is affected by a conserved tryptophan and its N-terminal region', FEBS Open Bio, 6, pp. 1320 - 1330, http://dx.doi.org/10.1002/2211-5463.12153
    Journal articles | 2016
    Hamey JJ; Winter DL; Yagoub D; Overall CM; Hart-Smith G; Wilkins MR, 2016, 'Novel N-terminal and lysine methyltransferases that target translation elongation factor 1A in yeast and human', Molecular and Cellular Proteomics, 15, pp. 164 - 176, http://dx.doi.org/10.1074/mcp.M115.052449
    Journal articles | 2015
    Yagoub D; Tay AP; Chen Z; Hamey JJ; Cai C; Chia SZ; Hart-Smith G; Wilkins MR, 2015, 'Proteogenomic Discovery of a Small, Novel Protein in Yeast Reveals a Strategy for the Detection of Unannotated Short Open Reading Frames', Journal of Proteome Research, 14, pp. 5038 - 5047, http://dx.doi.org/10.1021/acs.jproteome.5b00734
    Journal articles | 2014
    Zhang L; Hamey JJ; Hart-Smith G; Erce MA; Wilkins MR, 2014, 'Elongation factor methyltransferase 3 - A novel eukaryotic lysine methyltransferase', Biochemical and Biophysical Research Communications, 451, pp. 229 - 234, http://dx.doi.org/10.1016/j.bbrc.2014.07.110