Dr Julie   Thoms
Senior Research Associate

Dr Julie Thoms

medicine-health
School of Medical Sciences

Dr Julie Thoms is a Senior Research Associate in the Adult Cancer Program and School of Medical Sciences. Julie received her PhD from the University of Sydney and then undertook postdoctoral studies at Cornell University (USA), and the University of Calgary (Canada).

Her primary research interests lie in understanding how gene regulatory networks control stem cell characteristics during normal and leukemic blood development, with the ultimate aim of using this knowledge to develop targeted cancer therapies.

PubMed

 

Phone
+61 2 9385 2527
Location
Level 2, Lowy Cancer Research Centre

Publications

  • Journal articles | 2021
    Dr Julie Thoms
    Yeola A; Subramanian S; Oliver RA; Lucas CA; Thoms JAI; Yan F; Olivier J; Chacon D; Tursky ML; Srivastava P; Potas JR; Hung T; Power C; Hardy P; Ma DD; Kilian KA; McCarroll J; Kavallaris M; Hesson LB; Beck D; Curtis DJ; Wong JWH; Hardeman EC; Walsh WR; Mobbs R; Chandrakanthan V; Pimanda JE, 2021, 'Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine', Science Advances, vol. 7, pp. eabd1929 - eabd1929, http://dx.doi.org/10.1126/sciadv.abd1929
    Journal articles | 2021
    Dr Julie Thoms
    Thoms JAI; Truong P; Subramanian S; Knezevic K; Harvey G; Huang Y; Seneviratne JA; Carter DR; Joshi S; Skhinas J; Chacon D; Shah A; de Jong I; Beck D; Gottgens B; Larsson J; Wong JWH; Zanini F; Pimanda JE, 2021, 'Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells.', Blood, http://dx.doi.org/10.1182/blood.2020009707
    Journal articles | 2020
    Dr Julie Thoms
    Khanna A; Thoms JAI; Stringer BW; Chung SA; Ensbey KS; Jue TR; Jahan Z; Subramanian S; Anande G; Shen H; Unnikrishnan A; McDonald KL; Day BW; Pimanda JE, 2020, 'Constitutive CHK1 Expression Drives a pSTAT3-CIP2A Circuit that Promotes Glioblastoma Cell Survival and Growth', Molecular cancer research : MCR, vol. 18, pp. 709 - 722, http://dx.doi.org/10.1158/1541-7786.MCR-19-0934
    Journal articles | 2020
    Dr Julie Thoms
    Richards LA; Kumari A; Knezevic K; Thoms JAI; von Jonquieres G; Napier CE; Ali Z; O'Brien R; Marks-Bluth J; Maritz MF; Pickett HA; Morris J; Pimanda JE; MacKenzie KL, 2020, 'DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts', Haematologica, vol. 105, pp. 1517 - 1526, http://dx.doi.org/10.3324/haematol.2018.215699
    Journal articles | 2020
    Dr Julie Thoms
    Carmichael CL; Wang J; Nguyen T; Kolawole O; Benyoucef A; de Mazière C; Milne AR; Samuel S; Gillinder K; Hediyeh-Zadeh S; Vo ANQ; Huang Y; Knezevic K; McInnes WRL; Shields BJ; Mitchell H; Ritchie ME; Lammens T; Lintermans B; van Vlierberghe P; Wong NC; Haigh K; Thoms JAI; Toulmin E; Curtis DJ; Oxley EP; Dickins RA; Beck D; Perkins A; McCormack MP; Davis MJ; Berx G; Zuber J; Pimanda JE; Kile BT; Goossens S; Haigh JJ, 2020, 'The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1', Blood, vol. 136, pp. 957 - 973, http://dx.doi.org/10.1182/blood.2019002548
    Journal articles | 2019
    Dr Julie Thoms
    Kumar P; Beck D; Galeev R; Thoms JAI; Talkhoncheh MS; de Jong I; Unnikrishnan A; Baudet A; Subramaniam A; Pimanda JE; Larsson J, 2019, 'HMGA2 promotes long-term engraftment and myeloerythroid differentiation of human hematopoietic stem and progenitor cells', Blood Advances, vol. 3, pp. 681 - 691, http://dx.doi.org/10.1182/bloodadvances.2018023986
    Journal articles | 2019
    Dr Julie Thoms
    Thoms JAI; Beck D; Pimanda JE, 2019, 'Transcriptional networks in acute myeloid leukemia', Genes Chromosomes and Cancer, vol. 58, pp. 859 - 874, http://dx.doi.org/10.1002/gcc.22794
    Journal articles | 2019
    Dr Julie Thoms
    Chacon D; Braytee A; Huang Y; Thoms J; Subramanian S; Sauerland MC; Bohlander SK; Braess J; Woermann BJ; Berdel WE; Hiddemann W; Gabrys B; Metzeler KH; Herold T; Pimanda J; Beck D, 2019, 'Prospective Identification of Acute Myeloid Leukemia Patients Who Benefit from Gene-Expression Based Risk Stratification', BLOOD, vol. 134, http://dx.doi.org/10.1182/blood-2019-129519
    Journal articles | 2019
    Dr Julie Thoms
    Carmichael C; Wang J; Nguyen T; De Maziere C; Milne A; Goossens S; Davis M; Zadeh S; Vo A; McCormack M; Shields B; Haigh K; Huang Y; Thoms J; Knezevic K; Ritchie M; Berx G; Pimanda J; Kile B; Haigh J, 2019, '2008 - ALTERED EXPRESSION OF EPITHELIAL TO MESENCHYMAL TRANSITION MODULATORS IN ACUTE MYELOID LEUKAEMIA - A MODEL OF LSD1 CORRUPTION', Experimental Hematology, vol. 76, pp. S44 - S44, http://dx.doi.org/10.1016/j.exphem.2019.06.282
    Journal articles | 2018
    Dr Julie Thoms
    Beck D; Thoms JAI; Palu C; Herold T; Shah A; Olivier J; Boelen L; Huang Y; Chacon D; Brown A; Babic M; Hahn C; Perugini M; Zhou X; Huntly BJ; Schwarzer A; Klusmann JH; Berdel WE; Wörmann B; Büchner T; Hiddemann W; Bohlander SK; To LB; Scott HS; Lewis ID; D'Andrea RJ; Wong JWH; Pimanda JE, 2018, 'A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients', Leukemia, vol. 32, pp. 263 - 272, http://dx.doi.org/10.1038/leu.2017.210
    Journal articles | 2018
    Dr Julie Thoms
    Liu Q; Thoms JAI; Nunez AC; Huang Y; Knezevic K; Packham D; Poulos RC; Williams R; Beck D; Hawkins NJ; Ward RL; Wong JWH; Hesson LB; Sloane MA; Pimanda JE, 2018, 'Disruption of a 35 KB enhancer impairs CTCF binding and MLH1 expression in colorectal cells', Clinical Cancer Research, vol. 24, pp. 4602 - 4611, http://dx.doi.org/10.1158/1078-0432.CCR-17-3678
    Journal articles | 2017
    Dr Julie Thoms
    Unnikrishnan A; Papaemmanuil E; Beck D; Deshpande NP; Verma A; Kumari A; Woll PS; Richards LA; Knezevic K; Chandrakanthan V; Thoms JAI; Tursky ML; Huang Y; Ali Z; Olivier J; Galbraith S; Kulasekararaj AG; Tobiasson M; Karimi M; Pellagatti A; Wilson SR; Lindeman R; Young B; Ramakrishna R; Arthur C; Stark R; Crispin P; Curnow J; Warburton P; Roncolato F; Boultwood J; Lynch K; Jacobsen SEW; Mufti GJ; Hellstrom-Lindberg E; Wilkins MR; MacKenzie KL; Wong JWH; Campbell PJ; Pimanda JE, 2017, 'Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic Syndromes', Cell Reports, vol. 20, pp. 572 - 585, http://dx.doi.org/10.1016/j.celrep.2017.06.067
    Journal articles | 2017
    Dr Julie Thoms
    Liu K; Beck D; Thoms JAI; Liu L; Zhao W; Pimanda JE; Zhou X, 2017, 'Annotating function to differentially expressed LincRNAs in myelodysplastic syndrome using a network-based method', Bioinformatics, vol. 33, pp. 2622 - 2630, http://dx.doi.org/10.1093/bioinformatics/btx280
    Journal articles | 2016
    Dr Julie Thoms
    Huang Y; Thoms JAI; Tursky ML; Knezevic K; Beck D; Chandrakanthan V; Suryani S; Olivier J; Boulton A; Glaros EN; Thomas SR; Lock RB; MacKenzie KL; Bushweller JH; Wong JWH; Pimanda JE, 2016, 'MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation', Leukemia, vol. 30, pp. 1552 - 1561, http://dx.doi.org/10.1038/leu.2016.55
    Journal articles | 2016
    Dr Julie Thoms
    Unnikrishnan A; Guan YF; Huang Y; Beck D; Thoms JAI; Peirs S; Knezevic K; Ma S; De Walle IV; De Jong IDE; Ali Z; Zhong L; Raftery MJ; Taghon T; Larsson J; MacKenzie KL; Van Vlierberghe P; Wong JWH; Pimanda JE, 2016, 'A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network', Nucleic Acids Research, vol. 44, pp. 10644 - 10661, http://dx.doi.org/10.1093/nar/gkw804
    Journal articles | 2016
    Dr Julie Thoms
    Poulos RC; Thoms JAI; Guan YF; Unnikrishnan A; Pimanda JE; Wong JWH, 2016, 'Functional Mutations Form at CTCF-Cohesin Binding Sites in Melanoma Due to Uneven Nucleotide Excision Repair across the Motif', Cell Reports, vol. 17, pp. 2865 - 2872, http://dx.doi.org/10.1016/j.celrep.2016.11.055
    Journal articles | 2016
    Dr Julie Thoms
    Thoms JAI; Knezevic K; Liu JJ; Glaros EN; Thai T; Qiao Q; Campbell H; Packham D; Huang Y; Papathanasiou P; Tunningley R; Whittle B; Yeung AWS; Chandrakanthan V; Hesson L; Chen V; Wong JWH; Purton LE; Ward RL; Thomas SR; Pimanda JE, 2016, 'Arrested hematopoiesis and vascular relaxation defects in mice with a mutation in Dhfr', Molecular and Cellular Biology, vol. 36, pp. 1222 - 1236, http://dx.doi.org/10.1128/MCB.01035-15
    Journal articles | 2016
    Dr Julie Thoms
    Nasrallah R; Fast EM; Solaimani P; Knezevic K; Eliades A; Patel R; Thambyrajah R; Unnikrishnan A; Thoms J; Beck D; Vink CS; Smith A; Wong J; Shepherd M; Kent D; Roychoudhuri R; Paul F; Klippert J; Hammes A; Willnow T; Göttgens B; Dzierzak E; Zon LI; Lacaud G; Kouskoff V; Pimanda JE, 2016, 'Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes', Blood, vol. 128, pp. 1928 - 1939, http://dx.doi.org/10.1182/blood-2016-02-697870
    Journal articles | 2015
    Dr Julie Thoms
    Tursky ML; Beck D; Thoms JAI; Huang Y; Kumari A; Unnikrishnan A; Knezevic K; Evans K; Richards LA; Lee E; Morris J; Goldberg L; Izraeli S; Wong JWH; Olivier J; Lock RB; MacKenzie KL; Pimanda JE, 2015, 'Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias', Leukemia, vol. 29, pp. 819 - 827, http://dx.doi.org/10.1038/leu.2014.299
    Journal articles | 2015
    Dr Julie Thoms
    Poulos RC; Thoms JAI; Shah A; Beck D; Pimanda JE; Wong JWH, 2015, 'Systematic screening of promoter regions pinpoints functional cis-regulatory mutations in a cutaneous melanoma genome', Molecular Cancer Research, vol. 13, pp. 1218 - 1226, http://dx.doi.org/10.1158/1541-7786.MCR-15-0146
    Journal articles | 2015
    Dr Julie Thoms
    Marks-Bluth J; Khanna A; Chandrakanthan V; Thoms J; Bee T; Eich C; Kang YC; Knezevic K; Qiao Q; Fitch S; Oxburgh L; Ottersbach K; Dzierzak E; de Bruijn MFTR; Pimanda JE, 2015, 'SMAD1 and SMAD5 expression is coordinately regulated by FLI1 and GATA2 during endothelial development', Molecular and Cellular Biology, vol. 35, pp. 2165 - 2172, http://dx.doi.org/10.1128/MCB.00239-15
    Journal articles | 2015
    Dr Julie Thoms
    Jing RBAB, 2015, 'Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells', Blood, vol. 125, pp. 273 - 283, http://dx.doi.org/10.1182/blood-2014-05-576470
    Journal articles | 2014
    Dr Julie Thoms
    Perera D; Chacon D; Thoms JA; Poulos RC; Shlien A; Beck D; Campbell PJ; Pimanda JE; Wong JW, 2014, 'Oncocis: Annotation of cis-regulatory mutations in cancer', Genome Biology, vol. 15, http://dx.doi.org/10.1186/s13059-014-0485-0
    Journal articles | 2013
    Dr Julie Thoms
    Beck D; Thoms JAI; Perera D; Schütte J; Unnikrishnan A; Knezevic K; Kinston SJ; Wilson NK; O'Brien TA; Göttgens B; Wong JWH; Pimanda JE, 2013, 'Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes', Blood, vol. 122, pp. e12 - e22, http://dx.doi.org/10.1182/blood-2013-03-490425
    Journal articles | 2013
    Dr Julie Thoms
    Diffner E; Beck D; Gudgin E; Thoms JA; Knezevic K; Pridans C; Foster S; Goode D; Lim WK; boelen L; Metzeler KH; Micklem G; Bohlander SK; Buske C; Burnett A; Ottersbach K; Vassiliou GS; Olivier J; Wong JWH; Goettgens B; Huntly BJ; Pimanda JE, 2013, 'Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia', Blood, vol. 121, pp. 2289 - 2300, http://dx.doi.org/10.1182/blood-2012-07-446120
    Journal articles | 2013
    Dr Julie Thoms
    Oram SH; Thoms J; Sive J; Calero-Nieto FJ; Kinston SJ; Schuette J; Knezevic K; Lock RB; Pimanda JE; Gottgens B, 2013, 'Bivalent promoter marks and a latent enhancer may prime the leukaemia oncogene LMO1 for ectopic expression in T-cell leukaemia', Leukemia, vol. 27, pp. 1348 - 1357, http://dx.doi.org/10.1038/leu.2013.2
    Journal articles | 2011
    Dr Julie Thoms
    Thoms JAI; Birger Y; Foster S; Knezevic K; Kirshenbaum Y; Chandrakanthan V; Jonquieres G; Spensberger D; Wong JW; Oram SH; Kinston SJ; Groner Y; Lock RB; MacKenzie KL; Gottgens B; Izraeli S; Pimanda JE, 2011, 'ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer', Blood, vol. 117, pp. 7079 - 7089, http://dx.doi.org/10.1182/blood-2010-12-317990
    Journal articles | 2011
    Dr Julie Thoms
    Pimanda J; Thoms J; Birger Y; Foster S; Knezevic K; Kirschenbaum Y; Chandrakanthan V; Lock R; MacKenzie K; Gottgens B; Izraeli S, 2011, 'ERG PROMOTES T-ACUTE LYMPHOBLASTIC LEUKEMIA AND IS TRANSCRIPTIONALLY REGULATED IN LEUKEMIC CELLS BY A STEM CELL ENHANCER', EXPERIMENTAL HEMATOLOGY, vol. 39, pp. S108 - S108, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000293801700179&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2010
    Dr Julie Thoms
    Oram SH; Thoms JAI; Pridans C; Janes ME; Kinston SJ; Anand S; Landry JR; Lock RB; Jayaraman PS; Huntly BJ; Pimanda JE; Gottgens B, 2010, 'A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients', Oncogene, vol. 29, pp. 5796 - 5808, http://dx.doi.org/10.1038/onc.2010.320
    Journal articles | 2008
    Dr Julie Thoms
    Thoms J; Loch H; Bamburg J; Gunning P; Weinberger R, 2008, 'A tropomyosin 1 induced defect in cytokinesis can be rescued by elevated expression of cofilin', Cell Motility and the Cytoskeleton, vol. 65, pp. 979 - 990, http://dx.doi.org/10.1002/cm.20320
    Journal articles | 2004
    Dr Julie Thoms
    Percival JM; Hughes JA; Brown DL; Schevzov G; Heimann K; Vrhovski B; Bryce N; Stow JL; Gunning PW, 2004, 'Targeting of a tropomyosin isoform to short microfilaments associated with the Golgi complex', Mol Biol Cell, vol. 15, pp. 268 - 280, http://dx.doi.org/10.1091/mbc.E03-03-0176
    Journal articles | 2003
    Dr Julie Thoms
    Hughes J; Cooke-yarborough C; Chadwick N; Schevzov G; Arbuckle S; Gunning P; Weinberger R, 2003, 'High-molecular-weight tropomyosins localize to the contractile rings of dividing CNS cells but are absent from malignant paediatric and adult CNS tumors.', Glia, vol. 42, pp. 25 - 35, http://dx.doi.org/10.1002/glia.10174
    Journal articles | 2003
    Dr Julie Thoms
    Yager M; Thoms J; Lovicu F; Gunning P; Weinberger R; O'Neill G, 2003, 'Functional analysis of the actin-binding protein, tropomyosin 1, in neuroblastoma.', British Journal of Cancer, vol. 89, pp. 860 - 863, http://dx.doi.org/10.1038/sj.bjc.6601201
    Journal articles | 2003
    Dr Julie Thoms
    Thoms J; Weckert H; Van holst pellekaan C; Benson E; Dunn I, 2003, 'Translocations into human chromosome 14 JH region: factors influencing downstream abortive immunoglobulin class switching.', Molecular Immunology, vol. 40, pp. 573 - 583, http://dx.doi.org/10.1016/j.molimm.2003.09.001
    Journal articles | 2003
    Dr Julie Thoms
    Mcgowan E; Weinberger R; Graham J; Hill H; Thoms J; O''neill G; Clarke C, 2003, 'Cytoskeletal responsiveness to progestins is dependent on progesterone receptor A levels', Molecular Endocrinology, vol. 31, pp. 241 - 253, http://dx.doi.org/10.1677/jme.0.0310241
    Journal articles | 2000
    Dr Julie Thoms
    Weckert HA; Hughes JA; Benson EM; Dunn IS, 2000, 'Quantifiable analysis of human immunoglobulin heavy chain class-switch recombination to all isotypes', J Immunol Methods, vol. 233, pp. 141 - 158, http://dx.doi.org/10.1016/S0022-1759(99)00132-5
    Journal articles |
    Dr Julie Thoms
    Yeola A; Subramanian S; Oliver RA; Lucas CA; Thoms JAI; Yan F; Olivier J; Chacon D; Tursky ML; Hung T; Power C; Hardy P; Ma DD; McCarroll J; Kavallaris M; Hesson LB; Beck D; Curtis DJ; Wong JWH; Hardeman EC; Walsh WR; Mobbs R; Chandrakanthan V; Pimanda JE, 'Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine', , http://dx.doi.org/10.1101/2020.06.04.130872
    Journal articles |
    Dr Julie Thoms
    Thoms JAI; Knezevic K; Harvey G; Huang Y; Seneviratne JA; Carter DR; Subramanian S; Skhinas J; Chacon D; Shah A; de Jong I; Beck D; Göttgens B; Larsson J; Wong JWH; Zanini F; Pimanda JE, 'Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells', , http://dx.doi.org/10.1101/2020.10.26.353797
  • Conference Abstracts | 2020
    Dr Julie Thoms
    Kugler E; Birger Y; Yong D; Thoms J; Rein A; Madiwale S; Pimanda J; Prive G; Izraeli S, 2020, 'AML-079: The PNT Domain of ERG Regulates Hematopoietic Stemness and is Required for the Maintenance of ERG-Induced Leukemia', in Clinical Lymphoma Myeloma and Leukemia, Elsevier BV, Vol. 20, pp. S180 - S181, http://dx.doi.org/10.1016/s2152-2650(20)30713-8
    Conference Abstracts | 2020
    Dr Julie Thoms
    Kugler E; Birger Y; Yong D; Thoms J; Rein A; Madiwale S; Pimanda J; Prive G; Izraeli S, 2020, 'The PNT Domain of ERG Regulates Hematopoietic Stemness and is Required for the Maintenance of ERG-Induced Leukemia', in CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, CIG MEDIA GROUP, LP, Vol. 20, pp. S180 - S181, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000564055100083&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Dr Julie Thoms
    Beck D; Thoms J; Palu C; Herold T; Shah A; Olivier J; Boelen L; Huang Y; Chacon D; Brown A; Babic M; Hahn C; Perugini M; Zhou X; Huntly B; Berdel W; Woermann B; Buechner T; Hiddemann W; Bohlander S; Scott H; Lewis I; D'Andrea R; Wong J; Pimanda J, 2016, 'INTEGRATIVE ANALYSIS OF LINCRNA EXPRESSION IN 922 ACUTE MYELOID LEUKEMIA PATIENTS REVEALS MULTIPLE PROGNOSTIC GENE SIGNATURES', in HAEMATOLOGICA, FERRATA STORTI FOUNDATION, Copenhagen, DENMARK, Vol. 101, pp. 208 - 209, presented at 21st Congress of the European-Hematology-Association, Copenhagen, DENMARK, 09 June 2016 - 12 June 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000379484600457&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Dr Julie Thoms
    Unnikrishnan A; Papaemmanuil E; Beck D; Verma A; Kumari A; Woll P; Richards L; Knezevic K; Chandrakanthan V; Thoms J; Tursky M; Huang Y; Ali Z; Olivier J; Galbraith S; Kulasekararaj A; Tobiasson M; Karimi M; Pellagatti A; Wilson S; Lindeman R; Young B; Ramakrishna R; Arthur C; Stark R; Crispin P; Curnow J; Warburton P; Roncolato F; Boultwood J; Lynch K; Jacobsen S; Mufti G; Hellstrom-Lindberg E; MacKenzie K; Wong J; Campbell P; Pimanda J, 2016, 'INTEGRATIVE GENOMICS IDENTIFIES THE MOLECULAR BASIS OF RESISTANCE TO AZACITIDINE THERAPY IN MYELODYSPLASTIC SYNDROMES', in HAEMATOLOGICA, FERRATA STORTI FOUNDATION, Copenhagen, DENMARK, Vol. 101, pp. 157 - 158, presented at 21st Congress of the European-Hematology-Association, Copenhagen, DENMARK, 09 June 2016 - 12 June 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000379484600349&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2016
    Dr Julie Thoms
    Unnikrishnan A; Papaemmanuil E; Beck D; Verma A; Kumari A; Woll P; Richards L; Knezevic K; Chandrakanthan V; Thoms J; Tursky ML; Huang Y; Ali Z; Olivier S; Galbraith S; Kulasekararaj A; Tobiasson M; Karimi M; Pellagatti A; Wilson S; Lindeman R; Young B; Ramakrishna R; Arthur C; Stark R; Crispin P; Curnow J; Warburton P; Roncolato F; Boultwood J; Lynch K; Jacobsen S; Mufti G; Hellstrom-Lindberg E; MacKenzie K; Wong J; Campbell P; Pimanda J, 2016, 'Integrative genomics identifies the molecular basis of resistance to Azacitidine therapy in Myelodysplastic Syndromes', in Integrative genomics identifies the molecular basis of resistance to Azacitidine therapy in Myelodysplastic Syndromes, Ferrata Storti Foundation, Copenhagen, Denmark, pp. 157 - 158, presented at 21st Congress Of The European Hematology Association (EHA), Copenhagen, Denmark, 09 June 2016 - 12 June 2016, https://synapse.mskcc.org/synapse/works/97032
    Conference Papers | 2015
    Dr Julie Thoms
    Avellino R; Havermans M; Erpelinck C; Sanders M; Groeschel S; Vandewerken H; Hoogenboezem RM; Rombouts E; Van Lom K; Van Strien P; De Looper H; Gebhard CC; Rehli M; Beck D; Thoms JAI; Erkeland S; Touw I; Pimanda JE; Bindels EJM; Delwel R, 2015, 'A Tissue-Specific Transcriptional Element for C/ebpa Is Required for HSC Maintenance and Neutrophil Development', in BLOOD, AMER SOC HEMATOLOGY, Orlando, FL, presented at 57th Annual Meeting of the American-Society-of-Hematology, Orlando, FL, 05 December 2015 - 08 December 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000368019001053&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2015
    Dr Julie Thoms
    Unnikrishnan A; Papaemmanuil E; Beck D; Kumari A, 2015, 'An Integrative Genomics Approach Uncovers the Basis of Resistance to AZA Therapy in MDS and CMML', in An Integrative Genomics Approach Uncovers the Basis of Resistance to, AMER SOC HEMATOLOGY, USA, presented at ASH Annual Meeting, USA, 05 December 2015 - 08 December 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000368019002147&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2014
    Dr Julie Thoms
    Unnikrishnan A; Beck D; Verma A; Richards LA; Thoms JAI; Kumari A; Galbraith S; Kulasekararaj A; Tobiasson M; Woll PS; Pellagatti A; Papaemmanuil E; Wilson SR; Lindeman R; Campbell PJ; Boultwood J; Lynch K; Jacobsen SEW; Mufti GJ; Hellstrom-Lindberg E; MacKenzie KL; Wong JWH; Pimanda JE, 2014, 'Identification of a Prognostic Gene Expression Signature for AZA Response in MDS and CMML Patients', in BLOOD, AMER SOC HEMATOLOGY, San Francisco, CA, presented at 56th Annual Meeting of the American-Society-of-Hematology, San Francisco, CA, 06 December 2014 - 09 December 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000349243501166&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2013
    Dr Julie Thoms
    Beck D; Thoms J; Perera D; Unnikrishnan A; Knezevic K; O'Brien T; Gottgens B; Wong J; Pimanda J, 2013, 'GENOME-WIDE ANALYSIS OF TRANSCRIPTIONAL REGULATORS IN HUMAN HSCS REVEALS A DENSELY INTERCONNECTED NETWORK OF CODING AND NON-CODING GENES', in EXPERIMENTAL HEMATOLOGY, ELSEVIER SCIENCE INC, Vienna, AUSTRIA, pp. S17 - S17, presented at 42nd Annual Scientific Meeting of the International-Society-for-Experimental-Hematology-and-Stem-Cells (ISEH), Vienna, AUSTRIA, 22 August 2013 - 25 August 2013, http://dx.doi.org/10.1016/j.exphem.2013.05.063
    Conference Presentations | 2012
    Dr Julie Thoms
    Diffner E; Beck D; Gudgin E; Thoms J; Knezevic K; Pridans C; Foster S; Goode D; Lim WK; Boelen L; Metzeler KH; Micklem G; Bohlander SK; Buske C; Burnett AK; Ottersbach K; Vassiliou G; Olivier J; Wong JWH; Gottgens B; Huntly B; Pimanda JE, 2012, 'Activity of a Heptad of Transcription Factors Is Associated with Stem Cell Programs and Clinical Outcome in Acute Myeloid Leukaemia', Vol. 120, presented at 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta, GA, 08 December 2012 - 11 December 2012, http://dx.doi.org/10.1182/blood.V120.21.3525.3525
    Conference Papers | 2010
    Dr Julie Thoms
    Pimanda J; Knezevic K; Bee T; Janes M; Thoms J; Wilson N; Kolb-Kokocinski A; Pencovic N; Groner Y; de Bruijn M; Goettgens B, 2010, 'A RUNX1-SMAD6 RHEOSTAT CONTROLS RUNX1 LEVELS AND REGULATES HEMATOPOIESIS IN THE DEVELOPING EMBRYO', in EXPERIMENTAL HEMATOLOGY, ELSEVIER SCIENCE INC, Melbourne, AUSTRALIA, pp. S17 - S18, presented at 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells, Melbourne, AUSTRALIA, 15 September 2010 - 18 September 2010, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000281168900035&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Awards

Grants

Media