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Dr Karen Mather
Senior Research Fellow

Dr Karen Mather

Medicine & Health
Centre for Healthy Brain Ageing

Research Interests:
My main research focus is to gain a better understanding of the genetic and environmental factors involved in ageing, longevity and age-related disease, including dementia. The 'omic factors that may be involved include variation at the nucleotide level, epistasis, transcriptomics, epigenetic variation,and gene-environmental interactions. Current research is being undertaken using large population cohorts of older Australians and utilising large international biobanks. The establishment of collaborations with national and international investigators and consortia is enabling investigation of these age-related questions on a larger scale.

Broad Research Areas:
Human Ageing, Genetics - Genome Analysis, Epigenomics, Transcriptomics, Gerontology - Geriatrics, Epidemiology, Psychiatry

Society Memberships & Professional Activities:
American Human Society of Genetics, International Society to Advance Alzheimer Research and Treatment (ISTAART), Australian Association of Gerontology , Participant in the CSIRO Scientists in Schools Program

Specific Research Keywords:
Genetics, Genomics, Ageing, Biomarker, Dementia, Epigenetics, Transcriptomics, Mental Health

Meet Our Researcher
Learn more about Dr Mather – click here to read her ‘Meet Our Researcher’ interview
Phone
+ 61 2 9399 1064
E-mail
karen.mather@unsw.edu.au
Location
School of Psychiatry, UNSW Neuroscience Research Australia (NeuRA) Barker St., Randwick NSW 2031 AUSTRALIA
  • Book Chapters | 2017
    Theobald A; Daly C; Yang Z; Mather KA; Muenchhoff J; Crawford J; Sachdev PS, 2017, 'Sydney Centenarian Study', in Pachana NA (ed.), Encyclopedia of Geropsychology, Springer, Singapore, pp. 2365 - 2372, http://dx.doi.org/10.1007/978-981-287-082-7_140
  • Journal articles | 2023
    2023, 'Aging Is Associated With Multidirectional Changes in Social Cognition: Findings From an Adult Life-Span Sample Ranging From 18 to 101 Years', The journals of gerontology. Series B, Psychological sciences and social sciences, 78, pp. 62 - 72, http://dx.doi.org/10.1093/geronb/gbac110
    Journal articles | 2023
    2023, 'Author Correction: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores (Nature Communications, (2021), 12, 1, (3417), 10.1038/s41467-021-22491-8)', Nature Communications, 14, pp. 716, http://dx.doi.org/10.1038/s41467-023-36192-x
    Journal articles | 2023
    2023, 'Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI', Brain : a journal of neurology, 146, pp. 492 - 506, http://dx.doi.org/10.1093/brain/awac290
    Journal articles | 2023
    2023, 'Genetic and environmental influences on fruit and vegetable consumption and depression in older adults', BMC Geriatrics, 23, pp. 67, http://dx.doi.org/10.1186/s12877-023-03745-0
    Journal articles | 2023
    2023, 'Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease', Nature Medicine, 29, pp. 950 - 962, http://dx.doi.org/10.1038/s41591-023-02268-w
    Journal articles | 2023
    2023, 'Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium', Alzheimer's and Dementia, http://dx.doi.org/10.1002/alz.12962
    Journal articles | 2022
    2022, 'Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (Nature Genetics, (2021), 53, 12, (1636-1648), 10.1038/s41588-021-00973-1)', Nature Genetics, 54, pp. 361 - 361, http://dx.doi.org/10.1038/s41588-022-01020-3
    Journal articles | 2022
    2022, 'Early life affects late-life health through determining DNA methylation across the lifespan: A twin study', eBioMedicine, 77, pp. 103927, http://dx.doi.org/10.1016/j.ebiom.2022.103927
    Journal articles | 2022
    2022, 'Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs', Human Brain Mapping, 43, pp. 300 - 328, http://dx.doi.org/10.1002/hbm.25354
    Journal articles | 2022
    2022, 'Genetic and Environmental Factors in Ageing and Age-Related Disease', Genes, 13, http://dx.doi.org/10.3390/genes13030396
    Journal articles | 2022
    2022, 'Genetic variants associated with longitudinal changes in brain structure across the lifespan', Nature Neuroscience, 25, pp. 421 - 432, http://dx.doi.org/10.1038/s41593-022-01042-4
    Journal articles | 2022
    2022, 'Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning', Molecular Psychiatry, 27, pp. 4419 - 4431, http://dx.doi.org/10.1038/s41380-022-01710-8
    Journal articles | 2022
    2022, 'Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS', Science Translational Medicine, 14, http://dx.doi.org/10.1126/scitranslmed.abj0264
    Journal articles | 2022
    2022, 'Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease', Alzheimer's & Dementia, 18, http://dx.doi.org/10.1002/alz.064953
    Journal articles | 2022
    2022, 'High polygenic risk score for exceptional longevity is associated with a healthy metabolic profile', GEROSCIENCE, 45, http://dx.doi.org/10.1007/s11357-022-00643-y
    Journal articles | 2022
    2022, 'Measuring Empathy Across the Adult Lifespan: A Comparison of Three Assessment Types', Assessment, pp. 10731911221127902, http://dx.doi.org/10.1177/10731911221127902
    Journal articles | 2022
    2022, 'New insights into the genetic etiology of Alzheimer’s disease and related dementias', Nature Genetics, 54, pp. 412 - 436, http://dx.doi.org/10.1038/s41588-022-01024-z
    Journal articles | 2022
    2022, 'Parental Life Span and Polygenic Risk Score of Longevity Are Associated With White Matter Hyperintensities', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 77, pp. 689 - 696, http://dx.doi.org/10.1093/gerona/glab323
    Journal articles | 2022
    2022, 'Polygenic resilience scores capture protective genetic effects for Alzheimer’s disease', Translational Psychiatry, 12, pp. 296, http://dx.doi.org/10.1038/s41398-022-02055-0
    Journal articles | 2022
    2022, 'Polygenic risk score analysis for amyotrophic lateral sclerosis leveraging cognitive performance, educational attainment and schizophrenia', European Journal of Human Genetics, 30, pp. 532 - 539, http://dx.doi.org/10.1038/s41431-021-00885-y
    Journal articles | 2022
    2022, 'The heritability of amyloid burden in older adults: the Older Australian Twins Study', Journal of neurology, neurosurgery, and psychiatry, 93, pp. 303 - 308, http://dx.doi.org/10.1136/jnnp-2021-326677
    Journal articles | 2021
    2021, '1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans', Translational Psychiatry, 11, pp. 182, http://dx.doi.org/10.1038/s41398-021-01213-0
    Journal articles | 2021
    2021, 'Age- and Sex-Related Topological Organization of Human Brain Functional Networks and Their Relationship to Cognition', Frontiers in Aging Neuroscience, 13, pp. 758817, http://dx.doi.org/10.3389/fnagi.2021.758817
    Journal articles | 2021
    2021, 'Associations between Alzheimer's disease polygenic risk scores and hippocampal subfield volumes in 17,161 UK Biobank participants', Neurobiology of Aging, 98, pp. 108 - 115, http://dx.doi.org/10.1016/j.neurobiolaging.2020.11.002
    Journal articles | 2021
    2021, 'Associations between nutrition and the incidence of depression in middle-aged and older adults: A systematic review and meta-analysis of prospective observational population-based studies', Ageing Research Reviews, 70, pp. 101403, http://dx.doi.org/10.1016/j.arr.2021.101403
    Journal articles | 2021
    2021, 'Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology', Nature Genetics, 53, pp. 1636 - 1648, http://dx.doi.org/10.1038/s41588-021-00973-1
    Journal articles | 2021
    2021, 'Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores', Nature Communications, 12, pp. 3417, http://dx.doi.org/10.1038/s41467-021-22491-8
    Journal articles | 2021
    2021, 'Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group', Molecular Psychiatry, 26, pp. 3884 - 3895, http://dx.doi.org/10.1038/s41380-019-0605-z
    Journal articles | 2021
    2021, 'Genome-wide association study of circulating interleukin 6 levels identifies novel loci', Human Molecular Genetics, 30, pp. 393 - 409, http://dx.doi.org/10.1093/hmg/ddab023
    Journal articles | 2021
    2021, 'Global and regional development of the human cerebral cortex: Molecular architecture and occupational aptitudes', Cerebral Cortex, 30, pp. 4121 - 4139, http://dx.doi.org/10.1093/CERCOR/BHAA035
    Journal articles | 2021
    2021, 'Investigating olfactory gene variation and odour identification in older adults', Genes, 12, pp. 669 - 669, http://dx.doi.org/10.3390/genes12050669
    Journal articles | 2021
    2021, 'Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders', Genome Biology, 22, pp. 90, http://dx.doi.org/10.1186/s13059-021-02275-5
    Journal articles | 2021
    2021, 'Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank', Scientific Reports, 11, pp. 14633, http://dx.doi.org/10.1038/s41598-021-94182-9
    Journal articles | 2021
    2021, 'Plasma lipidome is dysregulated in Alzheimer’s disease and is associated with disease risk genes', Translational Psychiatry, 11, http://dx.doi.org/10.1038/s41398-021-01362-2
    Journal articles | 2021
    2021, 'The influence of rs53576 polymorphism in the oxytocin receptor (OXTR) gene on empathy in healthy adults by subtype and ethnicity: a systematic review and meta-analysis', Reviews in the Neurosciences, http://dx.doi.org/10.1515/revneuro-2021-0038
    Journal articles | 2020
    2020, 'Age-dependent genetic variants associated with longitudinal changes in brain structure across the lifespan', , http://dx.doi.org/10.1101/2020.04.24.031138
    Journal articles | 2020
    2020, 'An investigation into early-life stress and cognitive function in older age', International Psychogeriatrics, 32, pp. 1325 - 1329, http://dx.doi.org/10.1017/S1041610219001583
    Journal articles | 2020
    2020, 'Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region with Cortical and Subcortical Morphology and Cognition', JAMA Psychiatry, 77, pp. 420 - 430, http://dx.doi.org/10.1001/jamapsychiatry.2019.3779
    Journal articles | 2020
    2020, 'Associations between Alzheimer’s disease polygenic risk scores and hippocampal subfield volumes in 17,161 UK Biobank participants', , http://dx.doi.org/10.1101/2020.10.24.20218925
    Journal articles | 2020
    2020, 'Causes of variation in epigenetic aging across the lifespan', , http://dx.doi.org/10.1101/2020.05.10.20097030
    Journal articles | 2020
    2020, 'Cerebral small vessel disease genomics and its implications across the lifespan', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-020-19111-2
    Journal articles | 2020
    2020, 'Common genetic variation indicates separate causes for periventricular and deep white matter hyperintensities', Stroke, 51, pp. 2112 - 2121, http://dx.doi.org/10.1161/STROKEAHA.119.027544
    Journal articles | 2020
    2020, 'Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia (Molecular Psychiatry, (2020), 25, 3, (584-602), 10.1038/s41380-018-0118-1)', Molecular Psychiatry, 25, pp. 692 - 695, http://dx.doi.org/10.1038/s41380-019-0358-8
    Journal articles | 2020
    2020, 'Development of a short-form version of the Reading the Mind in the Eyes Test for assessing theory of mind in older adults', International Journal of Geriatric Psychiatry, 35, pp. 1322 - 1330, http://dx.doi.org/10.1002/gps.5369
    Journal articles | 2020
    2020, 'Differential blood miRNA expression in brain amyloid imaging-defined Alzheimer's disease and controls', Alzheimer's research & therapy, 12, pp. 59, http://dx.doi.org/10.1186/s13195-020-00627-0
    Journal articles | 2020
    2020, 'Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia', Molecular Psychiatry, 25, pp. 584 - 602, http://dx.doi.org/10.1038/s41380-018-0118-1
    Journal articles | 2020
    2020, 'Downregulated transferrin receptor in the blood predicts recurrent MDD in the elderly cohort: a fuzzy forests approach', Journal of Affective Disorders, 267, pp. 42 - 48, http://dx.doi.org/10.1016/j.jad.2020.02.001
    Journal articles | 2020
    2020, 'Genetic and environmental causes of variation in epigenetic aging across the lifespan', Clinical Epigenetics, 12, http://dx.doi.org/10.1186/s13148-020-00950-1
    Journal articles | 2020
    2020, 'Genetic and environmental determinants of variation in the plasma lipidome of older Australian twins', , http://dx.doi.org/10.1101/2020.05.05.075606
    Journal articles | 2020
    2020, 'Genetic and environmental determinants of variation in the plasma lipidome of older australian twins', eLife, 9, pp. 1 - 28, http://dx.doi.org/10.7554/eLife.58954
    Journal articles | 2020
    2020, 'Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-020-18367-y
    Journal articles | 2020
    2020, 'Genetic influence on ageing-related changes in resting-state brain functional networks in healthy adults: a systematic review', Neuroscience & Biobehavioral Reviews, http://dx.doi.org/10.1016/j.neubiorev.2020.03.011
    Journal articles | 2020
    2020, 'Genome-wide Meta-analysis Finds the ACSL5-ZDHHC6 Locus Is Associated with ALS and Links Weight Loss to the Disease Genetics', Cell Reports, 33, pp. 108323, http://dx.doi.org/10.1016/j.celrep.2020.108323
    Journal articles | 2020
    2020, 'Going around in circles: Deciphering the role of circular RNAs in neurodegenerative disease', Current Opinion in Psychiatry, 33, pp. 141 - 147, http://dx.doi.org/10.1097/YCO.0000000000000582
    Journal articles | 2020
    2020, 'New insights on the genetic etiology of Alzheimer’s and related dementia', , http://dx.doi.org/10.1101/2020.10.01.20200659
    Journal articles | 2020
    2020, 'Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank', , http://dx.doi.org/10.1101/2020.09.17.268029
    Journal articles | 2020
    2020, 'Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-020-18534-1
    Journal articles | 2020
    2020, 'Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis', npj Genomic Medicine, 5, http://dx.doi.org/10.1038/s41525-020-0118-3
    Journal articles | 2020
    2020, 'Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis.', NPJ Genom Med, 5, pp. 10, http://dx.doi.org/10.1038/s41525-020-0118-3
    Journal articles | 2020
    2020, 'Social cognitive abilities in older adults with mild cognitive impairment and dementia', Alzheimer's & Dementia, 16, http://dx.doi.org/10.1002/alz.044231
    Journal articles | 2020
    2020, 'The genetic architecture of the human cerebral cortex', Science, 367, http://dx.doi.org/10.1126/science.aay6690
    Journal articles | 2020
    2020, 'The prevalence of limbic‐predominant age‐related TDP‐43 encephalopathy in the Sydney brain bank', Alzheimer's & Dementia, 16, http://dx.doi.org/10.1002/alz.037885
    Journal articles | 2020
    2020, 'Towards a better understanding of human brain ageing: An RNA sequencing study of neuroinflammatory, neurotransmission‐related and synaptic genes in two key brain regions over the lifespan', Alzheimer's & Dementia, 16, http://dx.doi.org/10.1002/alz.045746
    Journal articles | 2020
    2020, 'Unraveling the genetic contributions to complex traits across different ethnic groups', Nature Medicine, 26, pp. 467 - 469, http://dx.doi.org/10.1038/s41591-020-0834-3
    Journal articles | 2019
    2019, 'APOE Genotype Differentially Modulates Plasma Lipids in Healthy Older Individuals, with Relevance to Brain Health', Journal of Alzheimer's Disease, 72, pp. 703 - 716, http://dx.doi.org/10.3233/JAD-190524
    Journal articles | 2019
    2019, 'Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (Nature Communications, (2018), 9, 1, (2098), 10.1038/s41467-018-04362-x)', Nature Communications, 10, pp. 2068, http://dx.doi.org/10.1038/s41467-019-10160-w
    Journal articles | 2019
    2019, 'Common genetic variation indicates separate etiologies for periventricular and deep white matter hyperintensities', , http://dx.doi.org/10.1101/683367
    Journal articles | 2019
    2019, 'Common variants in Alzheimer’s disease: Novel association of six genetic variants with AD and risk stratification by polygenic risk scores', , http://dx.doi.org/10.1101/19012021
    Journal articles | 2019
    2019, 'Differential blood miRNA expression in brain amyloid imaging defined Alzheimer's disease and controls.', , http://dx.doi.org/10.21203/rs.2.17624/v1
    Journal articles | 2019
    2019, 'Exceptional longevity and polygenic risk for cardiovascular health', Genes, 10, http://dx.doi.org/10.3390/genes10030227
    Journal articles | 2019
    2019, 'Exploration of Shared Genetic Architecture Between Subcortical Brain Volumes and Anorexia Nervosa', MOLECULAR NEUROBIOLOGY, 56, pp. 5146 - 5156, http://dx.doi.org/10.1007/s12035-018-1439-4
    Journal articles | 2019
    2019, 'Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting', Neurology, 92, pp. E486 - E503, http://dx.doi.org/10.1212/WNL.0000000000006851
    Journal articles | 2019
    2019, 'Genetic architecture of subcortical brain structures in 38,851 individuals', Nature Genetics, 51, pp. 1624 - 1636, http://dx.doi.org/10.1038/s41588-019-0511-y
    Journal articles | 2019
    2019, 'The many ages of man: Diverse approaches to assessing ageing-related biological and psychological measures and their relationship to chronological age', Current Opinion in Psychiatry, 32, pp. 130 - 137, http://dx.doi.org/10.1097/YCO.0000000000000473
    Journal articles | 2018
    Ciobanu LG; Sachdev PS; Trollor JN; Reppermund S; Thalamuthu A; Mather KA; Cohen-Woods S; Stacey D; Toben C; Schubert KO; Baune BT, 2018, 'Co-expression network analysis of peripheral blood transcriptome identifies dysregulated protein processing in endoplasmic reticulum and immune response in recurrent MDD in older adults', Journal of Psychiatric Research, 107, pp. 19 - 27, http://dx.doi.org/10.1016/j.jpsychires.2018.09.017
    Journal articles | 2018
    Davies G; Lam M; Harris SE; Trampush JW; Luciano M; Hill WD; Hagenaars SP; Ritchie SJ; Marioni RE; Fawns-Ritchie C; Liewald DC M; Okely JA; Ahola-Olli AV; Barnes CL K; Bertram L; Bis JC; Burdick KE; Christoforou A; Derosse P; Djurovic S; Espeseth T; Giakoumaki S; Giddaluru S; Gustavson DE; Hayward C; Hofer E; Ikram MA; Karlsson R; Knowles E; Lahti J; Leber M; Li S; Mather KA; Melle I; Morris D; Oldmeadow C; Palviainen T; Payton A; Pazoki R; Petrovic K; Reynolds CA; Sargurupremraj M; Scholz M; Smith JA; Smith AV; Terzikhan N; Thalamuthu A; Trompet S; Van Der Lee SJ; Ware EB; Windham BG; Wright MJ; Yang J; Yu J; Ames D; Amin N; Amouyel P; Andreassen OA; Armstrong NJ; Assareh AA; Attia JR; Attix D; Avramopoulos D; Bennett DA; Böhmer AC; Boyle PA; Brodaty H; Campbell H; Cannon TD; Cirulli ET; Congdon E; Conley ED; Corley J; Cox SR; Dale AM; Dehghan A; Dick D; Dickinson D; Eriksson JG; Evangelou E; Faul JD; Ford I; Freimer NA; Gao H; Giegling I; Gillespie NA; Gordon SD; Gottesman RF; Griswold ME; Gudnason V; Harris TB; Hartmann AM; Hatzimanolis A; Heiss G; Holliday EG; Joshi PK; Kähönen M; Kardia SL R; Karlsson I; Kleineidam L, 2018, 'Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function', Nature Communications, 9, http://dx.doi.org/10.1038/s41467-018-04362-x
    Journal articles | 2018
    Gielen M; Hageman GJ; Antoniou EE; Nordfjall K; Mangino M; Balasubramanyam M; De Meyer T; Hendricks AE; Giltay EJ; Hunt SC; Nettleton JA; Salpea KD; Diaz VA; Farzaneh-Far R; Atzmon G; Harris SE; Hou L; Gilley D; Hovatta I; Kark JD; Nassar H; Kurz DJ; Mather KA; Willeit P; Zheng YL; Pavanello S; Demerath EW; Rode L; Bunout D; Steptoe A; Boardman L; Marti A; Needham B; Zheng W; Ramsey-Goldman R; Pellatt AJ; Kaprio J; Hofmann JN; Gieger C; Paolisso G; Hjelmborg JB H; Mirabello L; Seeman T; Wong J; Van Der Harst P; Broer L; Kronenberg F; Kollerits B; Strandberg T; Eisenberg DT A; Duggan C; Verhoeven JE; Schaakxs R; Zannolli R; Dos Reis RM R; Charchar FJ; Tomaszewski M; Mons U; Demuth I; Molli AE I; Cheng G; Krasnienkov D; D'Antono B; Kasielski M; McDonnell BJ; Ebstein RP; Sundquist K; Pare G; Chong M; Zeegers MP, 2018, 'Body mass index is negatively associated with telomere length: A collaborative cross-sectional meta-analysis of 87 observational studies', American Journal of Clinical Nutrition, 108, pp. 453 - 475, http://dx.doi.org/10.1093/ajcn/nqy107
    Journal articles | 2018
    Jiang J; Thalamuthu A; Ho JE; Mahajan A; Ek WE; Brown DA; Breit SN; Wang TJ; Gyllensten U; Chen MH; Enroth S; Januzzi JL; Lind L; Armstrong NJ; Kwok JB; Schofield PR; Wen W; Trollor JN; Johansson Ã…; Morris AP; Vasan RS; Sachdev PS; Mather KA, 2018, 'A meta-analysis of genome-wide association studies of growth differentiation factor-15 concentration in blood', Frontiers in Genetics, 9, http://dx.doi.org/10.3389/fgene.2018.00097
    Journal articles | 2018
    Revelas M; Thalamuthu A; Oldmeadow C; Evans TJ; Armstrong NJ; Kwok JB; Brodaty H; Schofield PR; Scott RJ; Sachdev PS; Attia JR; Mather KA, 2018, 'Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity', Mechanisms of Ageing and Development, 175, pp. 24 - 34, http://dx.doi.org/10.1016/j.mad.2018.06.002
    Journal articles | 2018
    Vojinovic D; Adams HH; Jian X; Yang Q; Smith AV; Bis JC; Teumer A; Scholz M; Armstrong NJ; Hofer E; Saba Y; Luciano M; Bernard M; Trompet S; Yang J; Gillespie NA; van der Lee SJ; Neumann A; Ahmad S; Andreassen OA; Ames D; Amin N; Arfanakis K; Bastin ME; Becker DM; Beiser AS; Beyer F; Brodaty H; Bryan RN; Bülow R; Dale AM; De Jager PL; Deary IJ; DeCarli C; Fleischman DA; Gottesman RF; van der Grond J; Gudnason V; Harris TB; Homuth G; Knopman DS; Kwok JB; Lewis CE; Li S; Loeffler M; Lopez OL; Maillard P; El Marroun H; Mather KA; Mosley TH; Muetzel RL; Nauck M; Nyquist PA; Panizzon MS; Pausova Z; Psaty BM; Rice K; Rotter JI; Royle N; Satizabal CL; Schmidt R; Schofield PR; Schreiner PJ; Sidney S; Stott DJ; Thalamuthu A; Uitterlinden AG; Valdés Hernández MC; Vernooij MW; Wen W; White T; Witte AV; Wittfeld K; Wright MJ; Yanek LR; Tiemeier H; Kremen WS; Bennett DA; Jukema JW; Paus T; Wardlaw JM; Schmidt H; Sachdev PS; Villringer A; Grabe HJ; Longstreth WT; van Duijn CM; Launer LJ; Seshadri S; Ikram MA; Fornage M, 2018, 'Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume', Nature Communications, 9, http://dx.doi.org/10.1038/s41467-018-06234-w
    Journal articles | 2018
    2018, 'Differential expression of synaptic and interneuron genes in the aging human prefrontal cortex', Neurobiology of Aging, 70, pp. 194 - 202, http://dx.doi.org/10.1016/j.neurobiolaging.2018.06.011
    Journal articles | 2018
    2018, 'Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group', BIORXIV, http://dx.doi.org/10.1101/460444
    Journal articles | 2018
    2018, 'Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium', BIORXIV, http://dx.doi.org/10.1101/409649
    Journal articles | 2018
    2018, 'Genome-wide average DNA methylation is determined in utero', International Journal of Epidemiology, 47, pp. 908 - 916, http://dx.doi.org/10.1093/ije/dyy028
    Journal articles | 2018
    2018, 'The genetic architecture of the human cerebral cortex', , http://dx.doi.org/10.1101/399402
    Journal articles | 2017
    Armstrong NJ; Mather KA; Thalamuthu A; Wright MJ; Trollor JN; Ames D; Brodaty H; Schofield PR; Sachdev PS; Kwok JB, 2017, 'Aging, exceptional longevity and comparisons of the Hannum and Horvath epigenetic clocks', Epigenomics, 9, pp. 689 - 700, http://dx.doi.org/10.2217/epi-2016-0179
    Journal articles | 2017
    Brouwer RM; Panizzon MS; Glahn DC; Hibar DP; Hua X; Jahanshad N; Abramovic L; de Zubicaray GI; Franz CE; Hansell NK; Hickie IB; Koenis MM G; Martin NG; Mather KA; McMahon KL; Schnack HG; Strike LT; Swagerman SC; Thalamuthu A; Wen W; Gilmore JH; Gogtay N; Kahn RS; Sachdev PS; Wright MJ; Boomsma DI; Kremen WS; Thompson PM; Hulshoff Pol HE, 2017, 'Genetic influences on individual differences in longitudinal changes in global and subcortical brain volumes: Results of the ENIGMA plasticity working group', Human Brain Mapping, 38, pp. 4444 - 4458, http://dx.doi.org/10.1002/hbm.23672
    Journal articles | 2017
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    Hibar DP; Adams HH H; Jahanshad N; Chauhan G; Stein JL; Hofer E; Renteria ME; Bis JC; Arias-Vasquez A; Ikram MK; Desrivières S; Vernooij MW; Abramovic L; Alhusaini S; Amin N; Andersson M; Arfanakis K; Aribisala BS; Armstrong NJ; Athanasiu L; Axelsson T; Beecham AH; Beiser A; Bernard M; Blanton SH; Bohlken MM; Boks MP; Bralten J; Brickman AM; Carmichael O; Chakravarty MM; Chen Q; Ching CR K; Chouraki V; Cuellar-Partida G; Crivello F; Den Braber A; Doan NT; Ehrlich S; Giddaluru S; Goldman AL; Gottesman RF; Grimm O; Griswold ME; Guadalupe T; Gutman BA; Hass J; Haukvik UK; Hoehn D; Holmes AJ; Hoogman M; Janowitz D; Jia T; Jørgensen KN; Karbalai N; Kasperaviciute D; Kim S; Klein M; Kraemer B; Lee PH; Liewald DC M; Lopez LM; Luciano M; MacAre C; Marquand AF; Matarin M; Mather KA; Mattheisen M; McKay DR; Milaneschi Y; Muñoz Maniega S; Nho K; Nugent AC; Nyquist P; Loohuis LM O; Oosterlaan J; Papmeyer M; Pirpamer L; Pütz B; Ramasamy A; Richards JS; Risacher SL; Roiz-Santiañez R; Rommelse N; Ropele S; Rose EJ; Royle NA; Rundek T; Sämann PG; Saremi A; Satizabal CL; Schmaal L; Schork AJ; Shen L; Shin J; Shumskaya E; Smith AV; Sprooten E; Strike LT; Teumer A, 2017, 'Novel genetic loci associated with hippocampal volume', Nature Communications, 8, http://dx.doi.org/10.1038/ncomms13624
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    Karlsson Linnér R; Marioni RE; Rietveld CA; Simpkin AJ; Davies NM; Watanabe K; Armstrong NJ; Auro K; Baumbach C; Bonder MJ; Buchwald J; Fiorito G; Ismail K; Iurato S; Joensuu A; Karell P; Kasela S; Lahti J; McRae AF; Mandaviya PR; Seppälä I; Wang Y; Baglietto L; Binder EB; Harris SE; Hodge AM; Horvath S; Hurme M; Johannesson M; Latvala A; Mather KA; Medland SE; Metspalu A; Milani L; Milne RL; Pattie A; Pedersen NL; Peters A; Polidoro S; Räikkönen K; Severi G; Starr JM; Stolk L; Waldenberger M; Eriksson JG; Esko T; Franke L; Gieger C; Giles GG; Hägg S; Jousilahti P; Kaprio J; Kähönen M; Lehtimäki T; Martin NG; Van Meurs JB C; Ollikainen M; Perola M; Posthuma D; Raitakari OT; Sachdev PS; Taskesen E; Uitterlinden AG; Vineis P; Wijmenga C; Wright MJ; Relton C; Davey Smith G; Deary IJ; Koellinger PD; Benjamin DJ, 2017, 'An epigenome-wide association study meta-analysis of educational attainment', Molecular Psychiatry, 22, pp. 1680 - 1690, http://dx.doi.org/10.1038/mp.2017.210
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    Muenchhoff J; Song F; Poljak A; Crawford JD; Mather KA; Kochan NA; Yang Z; Trollor JN; Reppermund S; Maston K; Theobald A; Kirchner-Adelhardt S; Kwok JB; Richmond RL; McEvoy M; Attia J; Schofield PW; Brodaty H; Sachdev PS, 2017, 'Plasma apolipoproteins and physical and cognitive health in very old individuals', Neurobiology of Aging, 55, pp. 49 - 60, http://dx.doi.org/10.1016/j.neurobiolaging.2017.02.017
    Journal articles | 2017
    Tsang RS M; Mather KA; Sachdev PS; Reppermund S, 2017, 'Systematic review and meta-analysis of genetic studies of late-life depression', Neuroscience and Biobehavioral Reviews, 75, pp. 129 - 139, http://dx.doi.org/10.1016/j.neubiorev.2017.01.028
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    Willems SM; Wright DJ; Day FR; Trajanoska K; Joshi PK; Morris JA; Matteini AM; Garton FC; Grarup N; Oskolkov N; Thalamuthu A; Mangino M; Liu J; Demirkan A; Lek M; Xu L; Wang G; Oldmeadow C; Gaulton KJ; Lotta LA; Miyamoto-Mikami E; Rivas MA; White T; Loh PR; Aadahl M; Amin N; Attia JR; Austin K; Benyamin B; Brage S; Cheng YC; Ciȩszczyk P; Derave W; Eriksson KF; Eynon N; Linneberg A; Lucia A; Massidda M; Mitchell BD; Miyachi M; Murakami H; Padmanabhan S; Pandey A; Papadimitriou I; Rajpal DK; Sale C; Schnurr TM; Sessa F; Shrine N; Tobin MD; Varley I; Wain LV; Wray NR; Lindgren CM; MacArthur DG; Waterworth DM; McCarthy MI; Pedersen O; Khaw KT; Kiel DP; Pitsiladis Y; Fuku N; Franks PW; North KN; Van Duijn CM; Mather KA; Hansen T; Hansson O; Spector T; Murabito JM; Richards JB; Rivadeneira F; Langenberg C; Perry JR B; Wareham NJ; Scott RA; Oei L; Zheng HF; Forgetta V; Leong A; Ahmad OS; Laurin C; Mokry LE; Ross S; Elks CE; Bowden J; Warrington NM; Murray A; Ruth KS; Tsilidis KK; Medina-Gómez C; Estrada K; Bis JC; Chasman DI; Demissie S; Enneman AW; Hsu YH; Ingvarsson T; Kähönen M; Kammerer C, 2017, 'Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness', Nature Communications, 8, http://dx.doi.org/10.1038/ncomms16015
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    2017, '19th Workshop of the International Stroke Genetics Consortium, April 28-29, 2016, Boston, Massachusetts, USA: 2016.001 MRI-defined cerebrovascular genomics-The CHARGE consortium.', Neurol Genet, 3, pp. S2 - S11, http://dx.doi.org/10.1212/NXG.0000000000000100
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    2017, 'An epigenome-wide association study of educational attainment (n = 10,767)', , http://dx.doi.org/10.1101/114637
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    2017, 'Conversion Discriminative Analysis on Mild Cognitive Impairment Using Multiple Cortical Features from MR Images', FRONTIERS IN AGING NEUROSCIENCE, 9, http://dx.doi.org/10.3389/fnagi.2017.00146
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    2017, 'Modelling genetic and environmental influences on depressive symptoms and their covariation with anxiety and vascular phenotypes: findings from the Older Australian Twins Study', Frontiers in Psychiatry, 8, http://dx.doi.org/10.3389/conf.fpsyt.2017.48.00014
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    2017, 'Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)', , http://dx.doi.org/10.1101/176511
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    2017, 'Risk Factors for Mild Cognitive Impairment, Dementia and Mortality: The Sydney Memory and Ageing Study', Journal of the American Medical Directors Association, 18, pp. 388 - 395, http://dx.doi.org/10.1016/j.jamda.2016.10.014
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    2017, 'Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort', Molecular Genetics & Genomic Medicine, 5, pp. 418 - 428, http://dx.doi.org/10.1002/mgg3.302
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    Ciobanu LG; Sachdev PS; Trollor JN; Reppermund S; Thalamuthu A; Mather KA; Cohen-Woods S; Baune BT, 2016, 'Differential gene expression in brain and peripheral tissues in depression across the life span: A review of replicated findings', Neuroscience and Biobehavioral Reviews, 71, pp. 281 - 293, http://dx.doi.org/10.1016/j.neubiorev.2016.08.018
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    Franke B; van Hulzen KJ E; Arias-Vasquez A; Bralten J; Hoogman M; Klein M; van Donkelaar MM J; Hakobjan MM H; Heister AJ G A M; Makkinje RR R; Naber MA M; van der Marel SS L; Mostert JC; Brunner HG; van Bokhoven H; Zwiers MP; Buitelaar JK; Fernández G; Fisher SE; Francks C; Stein JL; Hibar DP; Thompson PM; Ripke S; Anttila V; Neale BM; Farh KH; Bulik-Sullivan B; Huang H; Fromer M; Goldstein JI; Daly MJ; Walters RK; Smoller JW; Lee P; Belliveau RA; Bergen SE; Bevilacqua E; Chambert KD; Genovese G; O'Dushlaine C; Scolnick EM; McCarroll SA; Moran JL; Palotie A; Petryshen TL; Erk S; Heinz A; Mohnke S; Romanczuk-Seiferth N; Walter H; DeLisi LE; McCarley RW; Mesholam-Gately RI; Seidman LJ; Nichols TE; Neale MC; McIntosh AM; Papmeyer M; Sprooten E; Lawrie SM; Sussmann JE; McMahon FJ; Yao Y; Meyer-Lindenberg A; Schwarz E; Grimm O; Mattheisen M; Agerbo E; Demontis D; Hansen T; Mors O; Olsen L; Rasmussen HB; Børglum AD; Mortensen PB; Werge T; Andreassen OA; Brown AA; Athanasiu L; Hartberg CB; Haukvik U; Melle I; Gruber O; Kraemer B; Keil M; Sachdev PS; Mather KA; Thalamuthu A; Armstrong NJ; Assareh AA; Brodaty H; Reppermund S; Wen W; Roiz-Santiañez R; Perez-Iglesias R; Saykin AJ; Kim S; Nho K; Risacher SL, 2016, 'Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept', Nature Neuroscience, 19, pp. 420 - 431, http://dx.doi.org/10.1038/nn.4228
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    Heffernan M; Mather KA; Xu J; Assareh AA; Kochan NA; Reppermund S; Draper B; Trollor JN; Sachdev P; Brodaty H, 2016, 'Alcohol Consumption and Incident Dementia: Evidence from the Sydney Memory and Ageing Study', Journal of Alzheimer's Disease, 52, pp. 529 - 538, http://dx.doi.org/10.3233/JAD-150537
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    Ibrahim-Verbaas CA; Bressler J; Debette S; Schuur M; Smith AV; Bis JC; Davies G; Trompet S; Smith JA; Wolf C; Chibnik LB; Liu Y; Vitart V; Kirin M; Petrovic K; Polasek O; Zgaga L; Fawns-Ritchie C; Hoffmann P; Karjalainen J; Lahti J; Llewellyn DJ; Schmidt CO; Mather KA; Chouraki V; Sun Q; Resnick SM; Rose LM; Oldmeadow C; Stewart M; Smith BH; Gudnason V; Yang Q; Mirza SS; Jukema JW; DeJager PL; Harris TB; Liewald DC; Amin N; Coker LH; Stegle O; Lopez OL; Schmidt R; Teumer A; Ford I; Karbalai N; Becker JT; Jonsdottir MK; Au R; Fehrmann RS N; Herms S; Nalls M; Zhao W; Turner ST; Yaffe K; Lohman K; Van Swieten JC; Kardia SL R; Knopman DS; Meeks WM; Heiss G; Holliday EG; Schofield PW; Tanaka T; Stott DJ; Wang J; Ridker P; Gow AJ; Pattie A; Starr JM; Hocking LJ; Armstrong NJ; McLachlan S; Shulman JM; Pilling LC; Eiriksdottir G; Scott RJ; Kochan NA; Palotie A; Hsieh YC; Eriksson JG; Penman A; Gottesman RF; Oostra BA; Yu L; DeStefano AL; Beiser A; Garcia M; Rotter JI; Nöthen MM; Hofman A; Slagboom PE; Westendorp RG J; Buckley BM; Wolf PA; Uitterlinden AG; Psaty BM; Grabe HJ; Bandinelli S; Chasman DI, 2016, 'GWAS for executive function and processing speed suggests involvement of the CADM2 gene', Molecular Psychiatry, 21, pp. 189 - 197, http://dx.doi.org/10.1038/mp.2015.37
    Journal articles | 2016
    Lupton MK; Strike L; Hansell NK; Wen W; Mather KA; Armstrong NJ; Thalamuthu A; McMahon KL; de Zubicaray GI; Assareh AA; Simmons A; Proitsi P; Powell JF; Montgomery GW; Hibar DP; Westman E; Tsolaki M; Kloszewska I; Soininen H; Mecocci P; Velas B; Lovestone S; Brodaty H; Ames D; Trollor JN; Martin NG; Thompson PM; Sachdev PS; Wright MJ, 2016, 'The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume', Neurobiology of Aging, 40, pp. 68 - 77, http://dx.doi.org/10.1016/j.neurobiolaging.2015.12.023
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    Mather KA; Armstrong NJ; Thalamuthu A; Kwok JB J, 2016, 'Tick tock: DNA methylation, the epigenetic clock and exceptional longevity', Epigenomics, 8, pp. 1577 - 1582, http://dx.doi.org/10.2217/epi-2016-0137
    Journal articles | 2016
    Mather KA; Thalamuthu A; Oldmeadow C; Song F; Armstrong NJ; Poljak A; Holliday EG; McEvoy M; Kwok JB; Assareh AA; Reppermund S; Kochan NA; Lee T; Ames D; Wright MJ; Trollor JN; Schofield PW; Brodaty H; Scott RJ; Schofield PR; Attia JR; Sachdev PS, 2016, 'Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults', Scientific Reports, 6, pp. 23675, http://dx.doi.org/10.1038/srep23675
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    Mohan A; Mather KA; Thalamuthu A; Baune BT; Sachdev PS, 2016, 'Gene expression in the aging human brain: An overview', Current Opinion in Psychiatry, 29, pp. 159 - 167, http://dx.doi.org/10.1097/YCO.0000000000000238
    Journal articles | 2016
    Poljak A; Crawford JD; Smythe GA; Brodaty H; Slavin MJ; Kochan NA; Trollor JN; Wen W; Mather KA; Assareh AA; Ng PC; Sachdev PS, 2016, 'The relationship between plasma aβ levels, cognitive function and brain volumetrics: Sydney memory and ageing study', Current Alzheimer Research, 13, pp. 243 - 255, http://dx.doi.org/10.2174/1567205013666151218150202
    Journal articles | 2016
    Sachdev PS; Thalamuthu A; Mather KA; Ames D; Wright MJ; Wen W; Bowden J; Lee T; Brodaty H; Crawford J; Duckworth T; Kang K; Garden N; Martin N; Lemmon C, 2016, 'White Matter Hyperintensities Are under Strong Genetic Influence', Stroke, 47, pp. 1422 - 1428, http://dx.doi.org/10.1161/STROKEAHA.116.012532
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    2016, 'Distinct Genetic Influences on Cortical and Subcortical Brain Structures', Scientific Reports, 6, pp. 32760 - 32760, http://dx.doi.org/10.1038/srep32760
    Journal articles | 2015
    Boraxbekk CJ; Ames D; Kochan NA; Lee T; Thalamuthu A; Wen W; Armstrong NJ; Kwok JB J; Schofield PR; Reppermund S; Wright MJ; Trollor JN; Brodaty H; Sachdev P; Mather KA, 2015, 'Investigating the influence of KIBRA and CLSTN2 genetic polymorphisms on cross-sectional and longitudinal measures of memory performance and hippocampal volume in older individuals', Neuropsychologia, 78, pp. 10 - 17, http://dx.doi.org/10.1016/j.neuropsychologia.2015.09.031
    Journal articles | 2015
    Chan JP L; Thalamuthu A; Oldmeadow C; Armstrong NJ; Holliday EG; McEvoy M; Kwok JB; Assareh AA; Peel R; Hancock SJ; Reppermund S; Menant J; Trollor JN; Brodaty H; Schofield PR; Attia JR; Sachdev PS; Scott RJ; Mather KA, 2015, 'Genetics of hand grip strength in mid to late life', Age (Dordrecht, Netherlands), 37, pp. 9745 - 9745, http://dx.doi.org/10.1007/s11357-015-9745-5
    Journal articles | 2015
    Dobson-Stone C; Shaw AD; Hallupp M; Bartley L; McCann H; Brooks WS; Loy CT; Schofield PR; Mather KA; Kochan NA; Sachdev PS; Halliday GM; Piguet O; Hodges JR; Kwok JB J, 2015, 'Is CHCHD10 Pro34Ser pathogenic for frontotemporal dementia and amyotrophic lateral sclerosis?', Brain, 138, pp. e385, http://dx.doi.org/10.1093/brain/awv115
    Journal articles | 2015
    Hibar DP; Stein JL; Renteria ME; Arias-Vasquez A; Desrivières S; Jahanshad N; Toro R; Wittfeld K; Abramovic L; Andersson M; Aribisala BS; Armstrong NJ; Bernard M; Bohlken MM; Boks MP; Bralten J; Brown AA; Mallar Chakravarty M; Chen Q; Ching CR K; Cuellar-Partida G; Den Braber A; Giddaluru S; Goldman AL; Grimm O; Guadalupe T; Hass J; Woldehawariat G; Holmes AJ; Hoogman M; Janowitz D; Jia T; Kim S; Klein M; Kraemer B; Lee PH; Olde Loohuis LM; Luciano M; MacAre C; Mather KA; Mattheisen M; Milaneschi Y; Nho K; Papmeyer M; Ramasamy A; Risacher SL; Roiz-Santiañez R; Rose EJ; Salami A; Sämann PG; Schmaal L; Schork AJ; Shin J; Strike LT; Teumer A; Van Donkelaar MM J; Van Eijk KR; Walters RK; Westlye LT; Whelan CD; Winkler AM; Zwiers MP; Alhusaini S; Athanasiu L; Ehrlich S; Hakobjan MM H; Hartberg CB; Haukvik UK; Heister AJ G A M; Hoehn D; Kasperaviciute D; Liewald DC M; Lopez LM; Makkinje RR R; Matarin M; Naber MA M; Reese McKay D; Needham M; Nugent AC; Pütz B; Royle NA; Shen L; Sprooten E; Trabzuni D; Van Der Marel SS L; Van Hulzen KJ E; Walton E; Wolf C; Almasy L; Ames D; Arepalli S; Assareh AA; Bastin ME; Brodaty H; Bulayeva KB; Carless MA; Cichon S; Corvin A; Curran JE; Czisch M, 2015, 'Common genetic variants influence human subcortical brain structures', Nature, 520, pp. 224 - 229, http://dx.doi.org/10.1038/nature14101
    Journal articles | 2015
    Lazarus J; Mather KA; Thalamuthu A; Kwok JB, 2015, 'Genetic factors and epigenetic mechanisms of longevity: Current perspectives', Epigenomics, 7, pp. 1339 - 1349, http://dx.doi.org/10.2217/epi.15.80
    Journal articles | 2015
    Mather KA; Armstrong NJ; Wen W; Kwok JB; Assareh AA; Thalamuthu A; Reppermund S; Duesing K; Wright MJ; Ames D; Trollor JN; Brodaty H; Schofield PR; Sachdev PS, 2015, 'Investigating the genetics of hippocampal volume in older adults without dementia', PLoS ONE, 10, pp. e0116920, http://dx.doi.org/10.1371/journal.pone.0116920
    Journal articles | 2015
    Willemsen G; Ward KJ; Bell CG; Christensen K; Bowden J; Dalgård C; Harris JR; Kaprio J; Lyle R; Magnusson PK E; Mather KA; Ordoňana JR; Perez-Riquelme F; Pedersen NL; Pietiläinen KH; Sachdev PS; Boomsma DI; Spector T, 2015, 'The Concordance and Heritability of Type 2 Diabetes in 34,166 Twin Pairs From International Twin Registers: The Discordant Twin (DISCOTWIN) Consortium', Twin Research and Human Genetics, 18, pp. 762 - 771, http://dx.doi.org/10.1017/thg.2015.83
    Journal articles | 2015
    Wu HZ Y; Ong KL; Seeher K; Armstrong NJ; Thalamuthu A; Brodaty H; Sachdev P; Mather K, 2015, 'Circulating microRNAs as biomarkers of alzheimer's disease: A systematic review', Journal of Alzheimer's Disease, 49, pp. 755 - 766, http://dx.doi.org/10.3233/JAD-150619
    Journal articles | 2015
    2015, 'DNA methylation in the apolipoprotein-A1 gene is associated with episodic memory performance in healthy older individuals', Journal of Alzheimer's Disease, 44, pp. 175 - 182, http://dx.doi.org/10.3233/JAD-141314
    Journal articles | 2015
    2015, 'Genetic contributions to variation in general cognitive function: A meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)', Molecular Psychiatry, 20, pp. 183 - 192, http://dx.doi.org/10.1038/mp.2014.188
    Journal articles | 2015
    2015, 'Genome-wide studies of verbal declarative memory in nondemented older people: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium', Biological Psychiatry, 77, pp. 749 - 763, http://dx.doi.org/10.1016/j.biopsych.2014.08.027
    Journal articles | 2014
    Assareh AA; Mather KA; Crawford JD; Wen W; Anstey KJ; Easteal S; Tan X; Mack HA; Kwok JB J; Schofield PR; Sachdev PS, 2014, 'Renin-angiotensin system genetic polymorphisms and brain white matter lesions in older australians', American Journal of Hypertension, 27, pp. 1191 - 1198, http://dx.doi.org/10.1093/ajh/hpu035
    Journal articles | 2014
    Coupland KG; Mellick GD; Silburn PA; Mather K; Armstrong NJ; Sachdev PS; Brodaty H; Huang Y; Halliday GM; Hallupp M; Kim WS; Dobson-Stone C; Kwok JB J, 2014, 'DNA methylation of the MAPT gene in Parkinson's disease cohorts and modulation by vitamin E In Vitro', Movement Disorders, 29, pp. 1606 - 1614, http://dx.doi.org/10.1002/mds.25784
    Journal articles | 2014
    Ising M; Mather KA; Zimmermann P; Brückl T; Höhne N; Heck A; Schenk LA; Rujescu D; Armstrong NJ; Sachdev PS; Reppermund S, 2014, 'Genetic effects on information processing speed are moderated by age - Converging results from three samples', Genes, Brain and Behavior, 13, pp. 501 - 507, http://dx.doi.org/10.1111/gbb.12132
    Journal articles | 2014
    Kanchibhotla SC; Mather KA; Thalamuthu A; Zhuang L; Schofield PR; Kwok JB J; Ames D; Wright MJ; Trollor JN; Wen W; Sachdev PS, 2014, 'Genetics of microstructure of the corpus callosum in older adults', PLoS ONE, 9, pp. e113181, http://dx.doi.org/10.1371/journal.pone.0113181
    Journal articles | 2014
    Mather KA; Kwok JB; Armstrong N; Sachdev PS, 2014, 'The role of epigenetics in cognitive ageing', International Journal of Geriatric Psychiatry, 29, pp. 1162 - 1171, http://dx.doi.org/10.1002/gps.4183
    Journal articles | 2014
    2014, 'Association of SORL1 gene variants with hippocampal and cerebral atrophy and Alzheimer's disease', Current Alzheimer Research, 11, pp. 558 - 563, http://dx.doi.org/10.2174/1567205011666140618101408
    Journal articles | 2014
    2014, 'Concordance between direct and imputed APOE genotypes using 1000 Genomes data', Journal of Alzheimer's Diseasse, 42, pp. 391 - 393, http://dx.doi.org/10.3233/JAD-140846
    Journal articles | 2014
    2014, 'The ENIGMA Consortium: Large-scale collaborative analyses of neuroimaging and genetic data', Brain Imaging and Behavior, 8, pp. 153 - 182, http://dx.doi.org/10.1007/s11682-013-9269-5
    Journal articles | 2013
    Dobson-Stone C; Polly P; Korgaonkar MS; Williams LM; Gordon E; Schofield PR; Mather K; Armstrong NJ; Wen W; Sachdev PS; Kwok JB J, 2013, 'GSK3B and MAPT polymorphisms are associated with grey matter and intracranial volume in healthy individuals', PLoS One, 8, pp. e71750, http://dx.doi.org/10.1371/journal.pone.0071750
    Journal articles | 2013
    Sachdev PS; Lipnicki DM; Crawford J; Reppermund S; Kochan NA; Trollor JN; Wen W; Draper B; Slavin MJ; Kang K; Lux O; Mather KA; Brodaty H; Team AS, 2013, 'Factors predicting reversion from mild cognitive impairment to normal cognition: a population-based study.', PLoS One, 8, http://dx.doi.org/10.1371/journal.pone.0059649
    Journal articles | 2013
    Schilling S; DeStefano AL; Sachdev PS; Choi SH; Mather KA; DeCarli CD; Wen W; Høgh P; Raz N; Au R; Beiser A; Wolf PA; Romero JR; Zhu YC; Lunetta KL; Farrer L; Dufouil C; Kuller LH; Mazoyer B; Seshadri S; Tzourio C; Debette S, 2013, 'APOE genotype and MRI markers of cerebrovascular disease', Neurology, 81, pp. 292 - 300, http://dx.doi.org/10.1212/WNL.0b013e31829bfda4
    Journal articles | 2013
    2013, 'Genetics of ageing-related changes in brain white matter integrity - a review', Ageing Research Reviews, 12, pp. 391 - 401, http://dx.doi.org/10.1016/j.arr.2012.10.003
    Journal articles | 2013
    2013, 'Risk Factors for Late-Life Cognitive Decline and Variation with Age and Sex in the Sydney Memory and Ageing Study', PLoS ONE, 8, pp. e65841, http://dx.doi.org/10.1371/journal.pone.0065841
    Journal articles | 2013
    2013, 'Sydney Memory and Ageing Study: an epidemiological cohort study of brain ageing and dementia', International Review of Psychiatry, 25, pp. 711 - 725, http://dx.doi.org/10.3109/09540261.2013.860890
    Journal articles | 2013
    2013, 'The Sydney Centenarian Study: methodology and profile of centenarians and near-centenarians', International Psychogeriatrics, 25, pp. 993 - 1005, http://dx.doi.org/10.1017/S1041610213000197
    Journal articles | 2013
    2013, 'The contribution of twins to the study of cognitive ageing and dementia: The Older Australian Twins Study', International Review of Psychiatry, 25, pp. 738 - 747, http://dx.doi.org/10.3109/09540261.2013.870137
    Journal articles | 2012
    2012, 'P2‐168: Recent findings from the Sydney Memory and Ageing Study (Sydney MAS)', Alzheimer's & Dementia, 8, pp. P317 - P318, http://dx.doi.org/10.1016/j.jalz.2012.05.874
    Journal articles | 2012
    2012, 'P4‐111: Olfaction identification in older adults: A genome‐wide association study', Alzheimer's & Dementia, 8, pp. P671 - P671, http://dx.doi.org/10.1016/j.jalz.2012.05.1814
    Journal articles | 2012
    2012, 'Plasma apolipoprotein levels are associated with cognitive status and decline in a community cohort of older individuals', PLoS One, 7, pp. e34078 - e34078, http://dx.doi.org/10.1371/journal.pone.0034078
    Journal articles | 2012
    2012, 'Risk Profiles of Subtypes of Mild Cognitive Impairment: The Sydney Memory and Ageing Study', Journal of the American Geriatrics Society, 60, pp. 24 - 33, http://dx.doi.org/10.1111/j.1532-5415.2011.03774.x
    Journal articles | 2012
    2012, 'Risk profiles for mild cognitive impairment vary by age and sex: The sydney memory and ageing study', American Journal of Geriatric Psychiatry, 20, pp. 854 - 865, http://dx.doi.org/10.1097/JGP.0b013e31825461b0
    Journal articles | 2011
    Mather KA; Jorm AF; Parslow RA; Christensen H, 2011, 'Is telomere length a biomarker of ageing? A review', Journals of Gerontology, Series A : Biological Sciences and Medical Sciences, 66, pp. 202 - 213, http://dx.doi.org/10.1093/gerona/glq180
    Journal articles | 2011
    2011, 'Grey matter atrophy of basal forebrain and hippocampus in mild cognitive impairment', Journal of Neurology Neurosurgery and Psychiatry, 82, pp. 487 - 493, http://dx.doi.org/10.1136/jnnp.2010.217133
    Journal articles | 2011
    2011, 'The Genetics of White Matter Lesions', CNS Neuroscience and Therapeutics, 17, pp. 525 - 540, http://dx.doi.org/10.1111/j.1755-5949.2010.00181.x
    Journal articles | 2010
    Mather KA; Jorm AF; Anstey KJ; Milburn PJ; Easteal S; Christensen H, 2010, 'Cognitive performance and leukocyte telomere length in two narrow age-range cohorts: A population study', BMC Geriatrics, 10, http://dx.doi.org/10.1186/1471-2318-10-62
    Journal articles | 2010
    Mather KA; Jorm AF; Milburn PJ; Tan X; Easteal S; Christensen H, 2010, 'No associations between telomere length and age-sensitive indicators of physical function in mid and later life', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 65 A, pp. 792 - 799, http://dx.doi.org/10.1093/gerona/glq050
    Journal articles | 2010
    2010, 'Sigma nonopioid intracellular receptor 1 mutations cause frontotemporal lobar degeneration - motor neuron disease', Annals of Neurology, 68, pp. 639 - 649, http://dx.doi.org/10.1002/ana.22274
    Journal articles | 2010
    2010, 'The Sydney Memory and Ageing Study (MAS): methodology and baseline medical and neuropsychiatric characteristics of an elderly epidemiological non-demented cohort of Australians aged 70-90 years', International Psychogeriatrics, 22, pp. 1248 - 1264, http://dx.doi.org/10.1017/S1041610210001067
    Journal articles | 2008
    Christensen H; Batterham PJ; Mackinnon AJ; Jorm AF; Mack HA; Mather KA; Anstey KJ; Sachdev PS; Easteal S, 2008, 'The association of APOE genotype and cognitive decline in interaction with risk factors in a 65-69 year old community sample', BMC Geriatrics, 8, pp. 1 - 10, http://dx.doi.org/10.1186/1471-2318-8-14
    Journal articles | 2007
    2007, 'APOE genotype and cognitive functioning in a large age-stratified population sample', Neuropsychology, 21, pp. 1 - 8, http://dx.doi.org/10.1037/0894-4105.21.1.1
    Journal articles | 2007
    2007, 'Memory complaints in a community sample aged 60-64 years: Associations with cognitive functioning, psychiatric symptoms, medical conditions, APOE genotype, hippocampus and amygdala volumes, and white-matter hyperintensities (vol 34, pg 1495, 2004)', PSYCHOLOGICAL MEDICINE, 37, pp. 763 - 763, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000246193200021&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2004
    2004, 'Memory complaints in a community sample aged 60-64 years: associations with cognitive functioning, psychiatric symptoms, medical conditions, APOE genotype, hippocampus and amygdala volumes, and white-matter hyperintensities', Psychological Medicine, 34, pp. 1495 - 1506, http://dx.doi.org/10.1017/S0033291704003162
    Journal articles | 1992
    Mather KA; White JF; Hudson PJ; McKimm-Breschkin JL, 1992, 'Expression of influenza neuraminidase in baculovirus-infected cells', Virus Research, 26, pp. 127 - 139, http://dx.doi.org/10.1016/0168-1702(92)90152-Y
    Journal articles | 1990
    Harley VR; Mather KA; Power BE; McKimm-Breschkin JL; Hudson PJ, 1990, 'Characterisation of an avian influenza virus nucleoprotein expressed in E. coli and in insect cells', Archives of Virology, 113, pp. 267 - 277, http://dx.doi.org/10.1007/BF01316679
    Journal articles | 1989
    Suva LJ; Mather KA; Gillespie MT; Webb GC; Ng KW; Winslow GA; Wood WI; Martin TJ; Hudson PJ, 1989, 'Structure of the 5' flanking region of the gene encoding human parathyroid-hormone-related protein (PTHrP)', Gene, 77, pp. 95 - 105, http://dx.doi.org/10.1016/0378-1119(89)90363-6
  • Working Papers | 2021
    2021, Parental lifespan and polygenic risk score of longevity are associated with white matter hyperintensities, Cold Spring Harbor Laboratory, http://dx.doi.org10.1101/2021.02.02.21251026
  • Conference Abstracts | 2022
    2022, 'Nature Versus Nurture – Studying the Relationships Between Diet and Depression in Older Adults', in Current Developments in Nutrition, Elsevier BV, Vol. 6, pp. 1118 - 1118, http://dx.doi.org/10.1093/cdn/nzac078.012
    Preprints | 2022
    2022, Brain structural covariances in the ageing brain in the UK Biobank, , http://dx.doi.org/10.1101/2022.07.26.501635
    Preprints | 2021
    2021, Age- and sex-related topological organisation of human brain functional networks and their relationship to cognition, , http://dx.doi.org/10.1101/2021.07.25.453293
    Preprints | 2021
    2021, Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology, , http://dx.doi.org/10.1101/2021.03.12.21253159
    Preprints | 2021
    2021, Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology, , http://dx.doi.org/10.21203/rs.3.rs-322430/v1
    Preprints | 2021
    2021, Genome-wide study of DNA methylation in Amyotrophic Lateral Sclerosis identifies differentially methylated loci and implicates metabolic, inflammatory and cholesterol pathways, , http://dx.doi.org/10.1101/2021.03.12.21253115
    Conference Abstracts | 2019
    2019, 'AGEDEP: Building an International Consortium on Geriatric Depression', in INTERNATIONAL PSYCHOGERIATRICS, CAMBRIDGE UNIV PRESS, Vol. 31, pp. 92 - 92, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000482963100158&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    2019, 'AGEDEP: Building an international consortium on geriatric depression', in BIPOLAR DISORDERS, WILEY, AUSTRALIA, Sydney, Vol. 21, pp. 115 - 115, presented at 21st Annual ISBD Conference on Global Advances in Bipolar Disorder and Depression, AUSTRALIA, Sydney, 20 March 2019 - 23 March 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000461513600257&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    2019, 'Differential expression of neuroinflammatory, neurotransmission-related and synaptic genes across 10 regions of the aging human brain: a microarray study [Poster Abstract P3-141]', in Alzheimer's & Dementia, Elsevier BV, Los Angeles, CA, USA, Vol. 15, pp. P985 - P986, presented at Alzheimer's Association International Conference (AAIC) 2019, Los Angeles, CA, USA, 14 July 2019 - 16 July 2019, http://dx.doi.org/10.1016/j.jalz.2019.06.3169
    Conference Abstracts | 2018
    2018, 'Differential expression of synaptic and interneuron genes in the aging human prefrontal cortex [Abstract O5-04-06]', in Alzheimer's & Dementia, Elsevier BV, Chicago, USA, Vol. 14, pp. P1654 - P1655, presented at Alzheimer’s Association International Conference (AAIC) 2018, Chicago, USA, 22 July 2018 - 26 July 2018, http://dx.doi.org/10.1016/j.jalz.2018.06.3018
    Preprints | 2018
    2018, Planar cell polarity pathway and development of the human visual cortex, , http://dx.doi.org/10.1101/404558
    Conference Abstracts | 2016
    Brouwer RM; Panizzon MS; Glahn DC; Hibar DP; Hua X; Jahanshad N; Abramovic L; de Zubicaray G; Franz CE; Hansell NK; Koenis MM G; Mather K; McMahon K; Strike LT; Thalamuthu A; Wen W; Boomsma DI; Gilmore DH; Gogtay N; Kahn RS; Kremen WS; Sachdev PS; Wright MJ; Thompson PM; Pol HE H, 2016, 'Genetic influences on longitudinal changes in brain volumes from the ENIGMA Plasticity Working Group [Poster Abstract 3469]', in Proceedings of the 22nd Annual Meeting of the Organization for Human Brain Mapping (OHBM), 22nd Annual Meeting of the Organization for Human Brain Mapping (OHBM), Geneva, Switzerland, presented at 22nd Annual Meeting of the Organization for Human Brain Mapping (OHBM), Geneva, Switzerland, 26 June 2016 - 30 June 2016
    Conference Abstracts | 2016
    Li S; Wong EM; Dugue P-A; Kim E; Joo J-HE; McRae AF; Milne RL; Apicella C; Armstrong NJ; Sachdev PS; Mather KA; Thalamuthu A; Wright MJ; Ames D; Wray N; Montgomery G; Spector TD; Sung J; Craig JM; Saffery R; Dongen JV; Giles GG; Southey MC; Hoppe JL, 2016, 'A measure of genome-wide average DNA methylation, which is also a risk factor for breast cancer, is determined in utero: insights from seven twin and family studies of different stages of the lifespan [Abstract]', in Twin Research and Human Genetics, Cambridge University Press (CUP), Brisbane, Australia, Vol. 19, pp. 517 - 517, presented at ISTS Satellite Meeting, Brisbane, Australia, 20 June 2016, http://dx.doi.org/10.1017/thg.2016.66
    Conference Abstracts | 2016
    Mohan A; Thalamuthu A; Weickert C; Mather K; Sachdev P, 2016, 'A study of gene expression in the ageing human brain', in BEHAVIOR GENETICS, SPRINGER, AUSTRALIA, Brisbane, Vol. 46, pp. 797 - 797, presented at 46th Annual Meeting of the Behavior-Genetics-Association, AUSTRALIA, Brisbane, 20 June 2016 - 23 June 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000386706600092&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2016
    Sachdev P; Thalamuthu A; Mather K; Ames D; Wright M; Wen W, 2016, 'White matter hyperintensities have a strong genetic influence', in BEHAVIOR GENETICS, SPRINGER, AUSTRALIA, Brisbane, pp. 804 - 804, presented at 46th Annual Meeting of the Behavior-Genetics-Association, AUSTRALIA, Brisbane, 20 June 2016 - 23 June 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000386706600113&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Sachdev PS; Bowden JL; Lee T; Wen W; Ames D; Baune BT; Brodaty H; Crawford J; Kang K; Mather K; Lammel A; Samaras K; Schofield PR; Thalamuthu A; Trollor JN; Wright MJ, 2016, 'The Older Australian Twins Study - findings from the first 10 years [Oral Abstract]', in Twin Research and Human Genetics, Cambridge University Press (CUP), Vol. 19, pp. 519 - 519, presented at ISTS Satellite Meeting, 20 June 2016, http://dx.doi.org/10.1017/thg.2016.66
    Conference Abstracts | 2016
    Sachdev PS; Thalamuthu A; Mather K; Ames D; Wright M; Wen W, 2016, 'White matter hyperintensities have a strong genetic influence [Abstract]', in Behavior Genetics, Behavior Genetics Association 46th Annual Meeting, Brisbane, Australia, Vol. 46, pp. 804 - 804, presented at Behavior Genetics Association 46th Annual Meeting, Brisbane, Australia, 20 June 2016 - 23 June 2016, http://dx.doi.org/10.1007/s10519-016-9812-4
    Conference Abstracts | 2016
    2016, 'Genome-Wide Gene Expression Signature Of Depression [Abstract]', in European Neuropsychopharmacology, Elsevier, Jerusalem, Israel, Vol. 27, pp. S484 - S484, presented at XXIV World Congress of Psychiatric Genetics (WCPG), Jerusalem, Israel, 30 October 2016 - 04 November 2016, http://dx.doi.org/10.1016/j.euroneuro.2016.09.573
    Conference Abstracts | 2016
    2016, 'Plasma apolipoproteins and physical and cognitive health in very old individuals.', in Alzheimer's & Dementia, Alzheimer's Association International Conference (AAIC) 2016, Toronto, Canada, Vol. 12, pp. P868 - P868, presented at Alzheimer's Association International Conference (AAIC) 2016, Toronto, Canada, 24 July 2016 - 28 July 2016, http://dx.doi.org/10.1016/j.jalz.2016.06.1786
    Conference Abstracts | 2016
    2016, 'Transcriptome Signature of Depression [Abstract]', in European Neuropsychopharmacology, Elsevier, Jerusalem, Israel, Vol. 27, pp. S513 - S513, presented at XIV World Congress of Psychiatric Genetics (WCPG), Jerusalem, Israel, 30 October 2016 - 04 November 2016, http://dx.doi.org/10.1016/j.euroneuro.2016.09.625
    Conference Abstracts | 2015
    Brouwer RM; Glahn DC; Hibar DP; Hua X; Jahanshad N; Abramovic L; Franz CE; Hansell NK; Koenis MM G; Mather K; Panizzon MS; Strike LT; Swagerman SC; Thalamuthu A; Wen W; Boomsma DI; Gilmore JH; Gogtay N; Kahn RS; Kremen WS; Sachdev PS; Wright MJ; Pol HE H; Thompson PM, 2015, 'Genetic influences on longitudinal changes in subcortical volumes: results from the ENIGMA Plasticity Group [Poster Abstract 4095]', in Proceedings of the 21st Annual Meeting of the Organization for Human Brain Mapping (OHBM), 21st Annual Meeting of the Organization for Human Brain Mapping (OHBM), Honolulu, Hawaii, USA, presented at 21st Annual Meeting of the Organization for Human Brain Mapping (OHBM), Honolulu, Hawaii, USA, 14 June 2015 - 18 June 2015
    Conference Abstracts | 2015
    Lupton MK; Strike L; Mather KA; Armstrong NJ; Thalamuthu A; McMahon KL; de Zubicaray GI; Assareh AA; Simmons A; Proitsi P; Powell JF; Montgomery GW; Hibar DP; Westman E; Tsolaki M; Kloszewska I; Soininen H; Mecocci P; Velas B; Lovestone S; Brodaty H; Ames D; Trollor J; Martin NG; Thompson PM; Sachdev PS; Wright MJ; Alzheimer’s Disease Neuroimaging Initiative , 2015, 'The use of genetic risk factors to assess prodromal brain changes in Alzheimer's disease [Poster abstract PgmNr 1229]', in Proceedings of the 2015 American Society Human Genetics Annual Meeting, American Society Human Genetics Annual Meeting, Baltimore, USA, presented at American Society Human Genetics Annual Meeting, Baltimore, USA, 06 October 2015 - 10 October 2015
    Conference Abstracts | 2015
    Mather K; Thalamuthu A; Chen BJ; Janitz M; Armstrong NJ; Sachdev PS; Sydney Centenarian Study Team ; Sydney Memory and Ageing Study Team , 2015, 'Longevity and the transcriptome: Identifying gene expression changes in long-lived individuals [Poster abstract PgmNr 3082]', in Proceedings of the 2015 American Society Human Genetics Annual Meeting, 2015 American Society Human Genetics Annual Meeting, Baltimore, USA, presented at 2015 American Society Human Genetics Annual Meeting, Baltimore, USA, 06 October 2015 - 10 October 2015
    Conference Abstracts | 2015
    2015, 'Genetic Influences on Brain Plasticity: First Results of the ENIGMA Plasticity Working Group [Abstract 223]', in Biological Psychiatry, Elsevier, Toronto, Canada, Vol. 77, pp. 84S - 84S, presented at 70th Annual Scientific Meeting of the Society of Biological Psychiatry on Stress, Emotion, Neurodevelopment and Psychopathology, Toronto, Canada, 14 May 2015 - 16 May 2015, http://dx.doi.org/10.1016/j.biopsych.2015.03.006
    Conference Abstracts | 2015
    2015, 'Genetic influences on longitudinal changes in subcortical volumes: results of the ENIGMA Plasticity Working Group [Abstract]', in Behavior Genetics, Springer Verlag (Germany), San Diego, CA, Vol. 45, pp. 662 - 663, presented at 45th Annual Meeting of the Behavior Genetics Association, San Diego, CA, 20 June 2015, http://dx.doi.org/10.1007/s10519-015-9742-6
    Conference Abstracts | 2015
    2015, 'Genome-wide association study identifies the SLC2A14 gene on chromosome 12P13 as a trans-acting locus for methylation of MAPT gene [Abstract MTU02-11]', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, Australia, Vol. 134, pp. 113 - 114, presented at 25th Biennial Meeting of the International Society for Neurochemistry jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, Australia, 23 August 2015 - 27 August 2015, http://dx.doi.org/10.1111/jnc.13188
    Conference Abstracts | 2015
    2015, 'Protein tyrosine phosphatase, receptor type, D as a candidate locus that may impact on exceptional longevity via methylation [Abstract WTH13-25]', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, Australia, Vol. 134, pp. 339 - 339, presented at 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, Australia, 23 August 2015 - 27 August 2015, http://dx.doi.org/10.1111/jnc.13188
    Conference Abstracts | 2015
    2015, 'Utility and challenges of whole-exome sequencing in the hunt for neurodegeneration genes [Abstract MTU02-05]', in Journal of Neurochemistry, Wiley: 12 months, Cairns, Australia, Vol. 134, pp. 111 - 111, presented at 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, Australia, 23 August 2015 - 27 August 2015, http://dx.doi.org/10.1111/jnc.13188
    Conference Abstracts | 2014
    Brodaty H; Heffernan M; Kochan NA; Reppermund S; Mather K; Assareh A; Xu J; Draper B; Trollor J; Sachdev PS, 2014, 'The effect of alcohol consumption and apolipoprotein E (APOE) 4 status on incident dementia over 4-years in the Sydney Memory and Ageing Study [Abstract P2-307]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2014, Copenhagen, Denmark, Vol. 10, pp. P591 - P591, presented at Alzheimer’s Association International Conference (AAIC) 2014, Copenhagen, Denmark, 12 July 2014 - 17 July 2014, http://dx.doi.org/10.1016/j.jalz.2014.05.986
    Conference Abstracts | 2014
    Chouraki VA; Jakobsdottir J; Mather K; Adams H; Mollon J; Oldmeadow C; Thalamuthu A; Tanaka T; Scott R; Levy D; Holliday L; Song F; Thambisetty M; Poljak A; Eiriksdottir G; Sachdev PS; Gupta VB; Martins R; Launer L; Dobson R; Brodaty H; Attia J; Lovestone S; Gudnason V; Ikram M; Seshadri S, 2014, 'A genome-wide meta-analysis of plasma clusterin levels in the CHARGE consortium [Abstract P3-071]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2014, Copenhagen, Denmark, Vol. 10, pp. P652 - P653, presented at Alzheimer’s Association International Conference (AAIC) 2014, Copenhagen, Denmark, 12 July 2014 - 17 July 2014, http://dx.doi.org/10.1016/j.jalz.2014.05.1159
    Conference Abstracts | 2014
    Mather KA; Thalamuthu A; Oldmeadow C; Song F; Armstrong NJ; Poljak A; Holliday L; McEvoy M; Kwok J; Assareh A; Reppermund S; Ames D; Wright M; Trollor JN; Schofield PW; Brodaty H; Scott RJ; Schofield PR; Attia JR; Sachdev PS, 2014, 'Genome-wide significant results identified for plasma apolipoprotein H levels [Abstract P4-012]', in Alzheimer's & Dementia, Alzheimer's Association International Conference (AAIC) 2014, Copenhagen, Denmark, Vol. 10, pp. P788 - P788, presented at Alzheimer's Association International Conference (AAIC) 2014, Copenhagen, Denmark, 12 July 2014 - 17 July 2014, http://dx.doi.org/10.1016/j.jalz.2014.05.1526
    Conference Abstracts | 2014
    Wen W; Mather K; Thalamuthu A; Zhu W; Jiang J; Sachdev PS, 2014, 'Heritability and lateralized genetic influence of brain structures in a population aged over 65 [Poster Abstract 3413]', in Proceedings of the 20th Annual Meeting of the Organization for Human Brain Mapping (OHBM), 20th Annual Meeting of the Organization for Human Brain Mapping (OHBM), Hamburg, Germanry, presented at 20th Annual Meeting of the Organization for Human Brain Mapping (OHBM), Hamburg, Germanry, 08 June 2014 - 12 June 2014
    Conference Abstracts | 2013
    Coupland K; Mather K; Sachdev P; Broe GA; Piguet O; Dobson-Stone C; Kwok J, 2013, 'MAPT methylation and implications for late-onset Alzheimer's disease [Abstract P4-327]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, Vol. 9, pp. P852 - P853, presented at Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, 13 July 2013 - 18 July 2013, http://dx.doi.org/10.1016/j.jalz.2013.08.161
    Conference Abstracts | 2013
    Kochan N; Bunce D; Pont S; Slavin M; Reppermund S; Brodaty H; Crawford J; Mather K; Kang K; Sachdev P, 2013, 'Reaction-time measures predict incident dementia over 4 years: The Sydney Memory and Ageing Study [Abstract O3-09-03]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, Vol. 9, pp. P536 - P536, presented at Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, 13 July 2013 - 18 July 2013, http://dx.doi.org/10.1016/j.jalz.2013.04.287
    Conference Abstracts | 2013
    Poljak A; Crawford J; Slavin M; Kochan N; Trollor J; Wen W; Mather K; Assareh A; Smythe GA; Brodaty H; Ng PC; Sachdev P, 2013, 'Plasma beta-amyloid correlates with cognition and brain volumetrics in mild cognitive impairment [Abstract P1-242]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, Vol. 9, pp. P241 - P241, presented at Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, 13 July 2013 - 18 July 2013, http://dx.doi.org/10.1016/j.jalz.2013.05.466
    Conference Abstracts | 2012
    Seeher K; Brodaty H; Low L-F; Reppermund S; Draper B; Kang K; Slavin M; Kochan N; Trollor J; Mather K; Sachdev P, 2012, 'To what extent does cognitive and functional decline in older persons affect the psychological well-being of cohabiting family members? [Abstract P2-335]', in Alzheimer's & Dementia, Alzheimer's Association International Conference (AAIC) 2012, Vancouver, Canada, Vol. 8, pp. P378 - P379, presented at Alzheimer's Association International Conference (AAIC) 2012, Vancouver, Canada, 14 July 2012 - 19 July 2012, http://dx.doi.org/10.1016/j.jalz.2012.05.1044
    Conference Abstracts | 2012
    Seeher K; Brodaty H; Low L-F; Reppermund S; Draper B; Kang K; Slavin M; Kochan N; Trollor JN; Mather K; Sachdev PS, 2012, 'Psychological distress in carers. Who gets it? A study on family members of people with MCI [Abstract Poster 29]', in National Dementia Research 6th Forum Program & Abstract Book, National Dementia Research 6th Forum, Canberra, Australia, pp. 107 - 108, presented at National Dementia Research 6th Forum, Canberra, Australia, 27 September 2012 - 28 September 2012
    Conference Abstracts | 2012
    2012, 'Rates of dementia amongst an exceptionally old cohort of Australians: The Sydney Centenarian Study [Abstract P1-080]', in Alzheimer's & dementia (Amsterdam, Netherlands)., Alzheimer's Association International Conference (AAIC), Vancouver, Canada, Vol. 8, pp. P134 - P134, presented at Alzheimer's Association International Conference (AAIC), Vancouver, Canada, 14 July 2012 - 19 July 2012, http://dx.doi.org/10.1016/j.jalz.2012.05.356
    Conference Abstracts | 2011
    Assareh A; Mather K; Armstrong N; Kwok J; Wen W; Brodaty H; Schofield P; Sachdev P, 2011, 'Genome-wide association study of white matter lesions in older individuals [Abstract P4-335]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) on Alzheimer’s disease 2011, Paris, France, Vol. 7, pp. e27 - e27, presented at Alzheimer’s Association International Conference (AAIC) on Alzheimer’s disease 2011, Paris, France, 16 July 2011 - 21 July 2011, http://dx.doi.org/10.1016/j.jalz.2011.09.080
    Conference Abstracts | 2011
    Assareh A; Mather K; Wen W; Anstey K; Easteal SE; Tan X; Mack H; Kwok J; Schofield P; Sachdev P, 2011, 'Association of PON2 Ser311Cys Polymorphism with Brain White Matter Lesions [Abstract P1-208]', in Alzheimer's & Dementia, lzheimer's Association International Conference (AAIC) 2011, Paris, France, Vol. 7, pp. S177 - S178, presented at lzheimer's Association International Conference (AAIC) 2011, Paris, France, 16 July 2011 - 21 July 2011, http://dx.doi.org/10.1016/j.jalz.2011.05.487
    Conference Abstracts | 2011
    Assareh A; Mather KA; Kwok J; Crawford J; Wen W; Brodaty H; Schofield PR; Sachdev PS, 2011, 'Interaction between APOE E4, hypertension and brain white matter lesions [Abstract POS-TUE-121]', in Proceedings of the 31st ANS Annual Meeting, Australian Neuroscience Society, online, pp. 117 - 117, presented at Australian Neuroscience Society 31st Annual Meeting, Auckland, 31 January 2011 - 03 February 2011
    Conference Abstracts | 2011
    Mather KA; Reppermund S; Assareh A; Crawford J; Kochan NA; Slavin MJ; Kwok J; Kang K; Trollor JN; Draper B; Schofield PR; Brodaty H; Sachdev PS, (ed.), 2011, 'Associations Between APOE ɛ4 and Instrumental Daily Activities of Living in A Community Sample of Older Adults [Abstract P1-247]', in Alzheimer's and Dementia, Elsevier, Orlando, Florida, Vol. 7, pp. S190 - S190, presented at International Conference on Alzheimer's Disease, Paris, France, 16 July 2011 - 21 July 2011, http://dx.doi.org/10.1016/j.jalz.2011.05.527
    Conference Abstracts | 2010
    Assareh A; Kwok JB J; Mather KA; Piguet O; Broe GA; Schofield PR; Sachdev PS, 2010, 'SORL1 gene variants are associated with brain white matter hyperintensities and dementia [Abstract Poster P1-082]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2010, Honolulu, Hawaii, USA, Vol. 6, pp. S197 - S198, presented at Alzheimer’s Association International Conference (AAIC) 2010, Honolulu, Hawaii, USA, 10 July 2010 - 15 July 2010, http://dx.doi.org/10.1016/j.jalz.2010.05.630
    Conference Presentations | 2010
    Levitan C; Sachdev P; Richmond RL, 2010, 'The Sydney Centenarian Study.', presented at Living to 100: The Science and the Art. The First Australasian Conference on Centenarians, Sydney, Australia, 12 November 2010 - 12 November 2010
    Conference Abstracts | 2010
    Mather KA; Assareh A; Kochan N; Crawford J; Kang K; Reppermund S; Trollor J; Kwok J; Draper B; Schofield P; Brodaty H; Sachdev P, 2010, 'APOE E4 carriers are associated with amnestic but not nonamnestic mild cognitive impairment in an elderly community sample [Abstract Poster P2-134]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2010, Honolulu, Hawaii, USA, Vol. 6, pp. S353 - S353, presented at Alzheimer’s Association International Conference (AAIC) 2010, Honolulu, Hawaii, USA, 10 July 2010 - 15 July 2010, http://dx.doi.org/10.1016/j.jalz.2010.05.1181
    Conference Abstracts | 2010
    Zhang H; Trollor J; Wen W; Zhu W; Crawford J; Kochan NA; Mather KA; Brodaty H; Reppermund S; Kang K; Slavin MJ; Sachdev PS, 2010, 'Gray matter atrophy of basal forebrain and hippocampus in mild cognitive impairment [Abstract 304 WTh-PM]', in Proceedings of the 16th Annual Meeting of the Organisation for Human Brain Mapping (OHBM), 16th Annual Meeting of the Organisation for Human Brain Mapping (OHBM), Barcelona, Spain, presented at 16th Annual Meeting of the Organisation for Human Brain Mapping (OHBM), Barcelona, Spain, 06 June 2010 - 10 June 2010
    Other | 2007
    Jorm AF; Butterworth P; Anstey KJ; Christensen H; Easteal S; Maller J; Mather KA; Turakulov RI; Wen W; Sachdev P, 2007, Erratum: Memory complaints in a community sample aged 60-64 years: Associations with cognitive functioning, psychiatric symptoms, medical conditions, APOE genotype, hippocampus and amygdala volumes, and white-matter hyperintensities (Psychological Medicine (2004) vol. 34 (1495-1506)), , http://dx.doi.org/10.1017/S0033291707000232

My Research Supervision

ILP, PhD including the following topics: Genomics/epigenomics of longevity; Brain ageing and transcriptomics/epigenomics, Circular RNAs and ageing; Diet and DNA methylation; Depression and diet; Identification of quantitative trait loci in older adults