Associate Professor Kirsty   Walters
Adjunct Associate Professor

Associate Professor Kirsty Walters

Medicine & Health
Sch Women's&Children's Health

Dr Kirsty Walters is a Senior Lecturer in Women’s and Children’s Health at the University of New South Wales (UNSW), Sydney, specialising in the field of female reproduction and ovarian function.

 

Background:

Dr Walters was awarded her PhD in 2005 from Edinburgh University, Scotland, and was then recruited by the ANZAC Research Institute (ARI) to undertake a post-doctoral position investigating the role androgens play in regulating female reproduction and physiology. In February 2016 the UNSW recruited her to head up the Ovarian Biology Laboratory based in the Wallace Wurth, which forms part of the world-leading biomedical precinct at UNSW.

 

Research interests:

Dr Walters’ research involves using customized genetic mouse models in combination with clinical samples and trials to dissect out the fundamental mechanisms regulating female reproduction and polycystic ovary syndrome (PCOS). In particular, her research has focused on understanding the role androgens play in regulating female fertility and PCOS. Findings from this research will identify therapeutic targets for improved treatment of female infertility and the wide range of health issues associated with PCOS, including obesity, insulin resistance, type 2 diabetes and cardiovascular risk.

 

Awards:

2018 - UNSW Medicine - Award for Research Excellence 2018                         

2018 - Discipline of Obstetrics and Gynaecology, School of Women’s & Children’s Health Research Award                                                        

2018 - Discipline of Obstetrics and Gynaecology, School of Women’s & Children’s Health Highly Commended Postgraduate Staff Teaching Award

2018 - Endocrine Society of Australia (ESA) Mid-Career Researcher Award

2017 - Society for Reproductive Biology - Reproduction, Fertility and Development publication of the year award

2017 - The Endocrine Society of Australia Ken Wynne Memorial Postdoctoral Research Award

2016 - Society for Reproductive Biology Visiting Lecturer Award

2015 - Society for Reproductive Biology, Newcastle, Reproduction Emerging Research Leader Award

2015 - Research Supervisor Award, Sydney Research, Sydney Local Health District

2011 - University of Sydney, Deans Early Researcher Award at the Reproductive, Maternal and Child Health Theme meeting

2009 - Australian Menopause Society Young Investigator Award

2006 - Society for Reproductive Biology Young Investigator Award

 

Publications:

Dr Walters currently has >45 peer-reviewed publications, in in top ranking journals including PNAS, Endocrinology, Human Reproduction Update and Biology of Reproduction.

 

Funding:

Dr Walters has a strong track record in successful category 1 competitive grant funding with the award of an ARC Discovery Early Career Researcher Award (DECRA) starting 2012 (DE120100796: $375,000 over 3 years), three NHMRC Project Grants as CIA starting 2010 (#632678: $520,500 over 3 years), 2012 (APP1022648: $493,515 over 3 years) and 2019 (APP1158540: $756,560 over 4 years), two other NHMRC Project Grants as CIC, starting 2011 (APP1008160: $408,374 over 3 years) and CIF, starting 2018 (APP1139763: $808,340 over 4 years) and an ARC Discovery grant as CIC, starting 2018 ($510,580 over 3 years).

 

Professional contributions:

Dr Walters has acted as referee for national (NHMRC project grants and review panel for the NHMRC Early Career Fellowships, and ARC Discovery Projects and Discovery Early Career Researcher Awards) and international (Medical Research Council , UK, Natural Sciences and Engineering Research Council of Canada, Wellbeing of Women, UK and Kentucky Science and Engineering Foundation, USA) grants. She has also served as an invited reviewer for 19 peer-review journals, including PNAS, Human Reproduction, Endocrinology, Biology of Reproduction, Molecular and Cellular Endocrinology, Fertility and Sterility, PLOS ONE and Reproduction. She is currently Program Organising Committee Co-Chair for the annual conference (2016-18) and councillor (on-going since 2013) for the Society for Reproductive Biology. She is also a member of the NHMRC CRE in Polycystic Ovary Syndrome Training Committee.

 

Phone
(02) 9385 2706
Location
Faculty of medicine Level 4, Room 421, Wallace Wurth Building, Botany Street Kensington NSW 2052

Publications

  • Book Chapters | 2019
    Associate Professor Kirsty Walters
    Findlay JK; Dunning KR; Gilchrist RB; Hutt KJ; Russell DL; Walters KA, 2019, 'Follicle Selection in Mammalian Ovaries', in The Ovary, Elsevier, pp. 3 - 21, http://dx.doi.org/10.1016/b978-0-12-813209-8.00001-7
    Book Chapters | 2018
    Associate Professor Kirsty Walters
    Findlay J; Dunning K; Gilchrist R; Hutt K; Russell D; Walters K, 2018, 'Follicle selection in mammalian ovaries', in The Ovary, Academic Press, London, England, pp. 3 - 21, https://www.elsevier.com/books/the-ovary/leung/978-0-12-813209-8
  • Journal articles | 2021
    Associate Professor Kirsty Walters
    Rodriguez Paris V; Edwards MC; Aflatounian A; Bertoldo MJ; Ledger WL; Handelsman DJ; Gilchrist RB; Walters KA, 2021, 'Pathogenesis of Reproductive and Metabolic PCOS Traits in a Mouse Model.', J Endocr Soc, vol. 5, pp. bvab060, http://dx.doi.org/10.1210/jendso/bvab060
    Journal articles | 2021
    Associate Professor Kirsty Walters
    Paris VR; Alexopoulos SJ; Hu Y; Shah DP; Aflatounian A; Edwards MC; Bertoldo M; Kyle HL; Walters KA, 2021, 'Metabolic PCOS Features Are Ameliorated by Mitochondrial Uncoupler BAM15 in a PCOS Mouse Model', Journal of the Endocrine Society, vol. 5, pp. A769 - A770, http://dx.doi.org/10.1210/jendso/bvab048.1565
    Journal articles | 2021
    Associate Professor Kirsty Walters
    Coyle C; Ruddenklau A; Prescott M; Walters KA; Campbell RE, 2021, 'Chronic Excess of Non-Aromatizable Androgens From Puberty Does Not Drive a Neuroendocrine Phenotype Observed in Other Preclinical Rodent Models of PCOS', Journal of the Endocrine Society, vol. 5, pp. A533 - A534, http://dx.doi.org/10.1210/jendso/bvab048.1086
    Journal articles | 2021
    Associate Professor Kirsty Walters
    Handelsman DJ; Walters KA; Ly LP, 2021, 'Simplified method to measure mouse fertility', Endocrinology (United States), vol. 161, pp. 1 - 6, http://dx.doi.org/10.1210/ENDOCR/BQAA114
    Journal articles | 2021
    Associate Professor Kirsty Walters
    Bertoldo MJ; Paris VR; Gook DA; Edwards MC; Wu K; Liang CJJ; Marinova MB; Wu LE; Walters KA; Gilchrist RB, 2021, 'Impact of nicotinamide mononucleotide on transplanted mouse ovarian tissue', Reproduction, vol. 161, pp. 215 - 226, http://dx.doi.org/10.1530/REP-20-0539
    Journal articles | 2021
    Associate Professor Kirsty Walters
    Sucquart IE; Nagarkar R; Edwards MC; Rodriguez Paris V; Aflatounian A; Bertoldo MJ; Campbell RE; Gilchrist RB; Begg DP; Handelsman DJ; Padmanabhan V; Anderson RA; Walters KA, 2021, 'Neurokinin 3 Receptor Antagonism Ameliorates Key Metabolic Features in a Hyperandrogenic PCOS Mouse Model', Endocrinology (United States), vol. 162, http://dx.doi.org/10.1210/endocr/bqab020
    Journal articles | 2021
    Associate Professor Kirsty Walters
    Rodriguez Paris V; Walters KA, 2021, 'Humanin: a potential treatment for PCOS?', Endocrinology, http://dx.doi.org/10.1210/endocr/bqab085
    Journal articles | 2020
    Associate Professor Kirsty Walters
    Rodriguez Paris V; Solon-Biet SM; Senior AM; Edwards MC; Desai R; Tedla N; Cox MJ; Ledger WL; Gilchrist RB; Simpson SJ; Handelsman DJ; Walters KA, 2020, 'Defining the impact of dietary macronutrient balance on PCOS traits', Nature Communications, vol. 11, pp. 5262, http://dx.doi.org/10.1038/s41467-020-19003-5
    Journal articles | 2020
    Associate Professor Kirsty Walters
    Aflatounian A; Edwards MC; Paris VR; Bertoldo MJ; Desai R; Gilchrist RB; Ledger WL; Handelsman DJ; Walters KA, 2020, 'Androgen signaling pathways driving reproductive and metabolic phenotypes in a PCOS mouse model', Journal of Endocrinology, vol. 245, pp. 381 - 395, http://dx.doi.org/10.1530/JOE-19-0530
    Journal articles | 2020
    Associate Professor Kirsty Walters
    Cox MJ; Edwards MC; Paris VR; Aflatounian A; Ledger WL; Gilchrist RB; Padmanabhan V; Handelsman DJ; Walters KA, 2020, 'Androgen Action in Adipose Tissue and the Brain are Key Mediators in the Development of PCOS Traits in a Mouse Model', Endocrinology (United States), vol. 161, pp. 1 - 15, http://dx.doi.org/10.1210/ENDOCR/BQAA061
    Journal articles | 2020
    Associate Professor Kirsty Walters
    Bertoldo MJ; Listijono DR; Ho WHJ; Riepsamen AH; Goss DM; Richani D; Jin XL; Mahbub S; Campbell JM; Habibalahi A; Loh WGN; Youngson NA; Maniam J; Wong ASA; Selesniemi K; Bustamante S; Li C; Zhao Y; Marinova MB; Kim LJ; Lau L; Wu RM; Mikolaizak AS; Araki T; Le Couteur DG; Turner N; Morris MJ; Walters KA; Goldys E; O'Neill C; Gilchrist RB; Sinclair DA; Homer HA; Wu LE, 2020, 'NAD+ Repletion Rescues Female Fertility during Reproductive Aging', Cell Reports, vol. 30, pp. 1670 - 1681.e7, http://dx.doi.org/10.1016/j.celrep.2020.01.058
    Journal articles | 2020
    Associate Professor Kirsty Walters
    Stener-Victorin E; Padmanabhan V; Walters KA; Campbell RE; Benrick A; Giacobini P; Dumesic DA; Abbott DH, 2020, 'Animal Models to Understand the Etiology and Pathophysiology of Polycystic Ovary Syndrome', Endocrine Reviews, vol. 41, http://dx.doi.org/10.1210/endrev/bnaa010
    Journal articles | 2020
    Associate Professor Kirsty Walters
    Walters KA, 2020, 'Polycystic ovary syndrome: Is it androgen or estrogen receptor?', Current Opinion in Endocrine and Metabolic Research, vol. 12, pp. 1 - 7, http://dx.doi.org/10.1016/j.coemr.2020.01.003
    Journal articles | 2020
    Associate Professor Kirsty Walters
    Cox MJ; Edwards MC; Aflatounian A; Paris VR; Ledger WL; Gilchrist RB; Handelsman DJ; Walters KA, 2020, 'SAT-018 Androgen Actions in Adipose Tissue and the Brain Are Key Mediators in the Development of Polycystic Ovary Syndrome', Journal of the Endocrine Society, vol. 4, http://dx.doi.org/10.1210/jendso/bvaa046.088
    Journal articles | 2020
    Associate Professor Kirsty Walters
    Paris VR; Kaakoush NO; Solon-Biet SM; Edwards MC; Ledger WL; Gilchrist RB; Simpson SJ; Handelsman DJ; Walters KA, 2020, 'MON-022 Dissecting the Interplay Between Diet and PCOS Pathology on Gut Microbiota in a PCOS Mouse Model', Journal of the Endocrine Society, vol. 4, http://dx.doi.org/10.1210/jendso/bvaa046.568
    Journal articles | 2019
    Associate Professor Kirsty Walters
    Bertoldo MJ; Caldwell ASL; Riepsamen AH; Lin D; Gonzalez MB; Robker RL; Ledger WL; Gilchrist RB; Handelsman DJ; Walters KA, 2019, 'A hyperandrogenic environment causes intrinsic defects that are detrimental to follicular dynamics in a PCOS mouse model', Endocrinology, vol. 160, pp. 699 - 715, http://dx.doi.org/10.1210/en.2018-00966
    Journal articles | 2019
    Associate Professor Kirsty Walters
    Stepto NK; Moreno-Asso A; McIlvenna LC; Walters KA; Rodgers RJ, 2019, 'Molecular Mechanisms of Insulin Resistance in Polycystic Ovary Syndrome: Unraveling the Conundrum in Skeletal Muscle?', Journal of Clinical Endocrinology and Metabolism, vol. 104, pp. 5372 - 5381, http://dx.doi.org/10.1210/jc.2019-00167
    Journal articles | 2019
    Associate Professor Kirsty Walters
    Walters KA; Paris VR; Aflatounian A; Handelsman DJ, 2019, 'Androgens and ovarian function: Translation from basic discovery research to clinical impact', Journal of Endocrinology, vol. 242, pp. R23 - R50, http://dx.doi.org/10.1530/JOE-19-0096
    Journal articles | 2019
    Associate Professor Kirsty Walters
    Burchall GF; Pouniotis DS; Teede HJ; Ranasinha S; Walters KA; Piva TJ, 2019, 'Expression of the plasminogen system in the physiological mouse ovary and in the pathological polycystic ovary syndrome (PCOS) state', Reproductive Biology and Endocrinology, vol. 17, pp. 33, http://dx.doi.org/10.1186/s12958-019-0472-0
    Journal articles | 2019
    Associate Professor Kirsty Walters
    Tarulli GA; Laven-Law G; Shehata M; Walters KA; Denis IM; Rahman MM; Handelsman DJ; Dean NR; Tilley WD; Hickey TE, 2019, 'Androgen Receptor Signalling Promotes a Luminal Phenotype in Mammary Epithelial Cells', Journal of Mammary Gland Biology and Neoplasia, vol. 24, pp. 99 - 108, http://dx.doi.org/10.1007/s10911-018-9406-2
    Journal articles | 2019
    Associate Professor Kirsty Walters
    Walters KA; Eid S; Edwards MC; Thuis-Watson R; Desai R; Bowman M; Marren AJ; Handelsman DJ, 2019, 'Steroid profiles by liquid chromatography-mass spectrometry of matched serum and single dominant ovarian follicular fluid from women undergoing IVF', Reproductive BioMedicine Online, vol. 38, pp. 30 - 37, http://dx.doi.org/10.1016/j.rbmo.2018.10.006
    Journal articles | 2019
    Associate Professor Kirsty Walters
    Aflatounian A; Edwards M; Gilchrist R; Bertoldo M; Ledger W; Handelsman D; Walters K, 2019, 'OR08-2 Androgen Receptor- Vs Estrogen Receptor-Mediated Actions in the Development of Distinct Clinical Polycystic Ovary Syndrome (PCOS) Phenotypes', Journal of the Endocrine Society, vol. 3, http://dx.doi.org/10.1210/js.2019-or08-2
    Journal articles | 2019
    Associate Professor Kirsty Walters
    Rodriguez Paris V; Solon-Biet S; Edwards M; Cox M; Ledger W; Gilchrist R; Simpson S; Handelsman D; Walters K, 2019, 'MON-231 Dietary Interventions Can Ameliorate Polycystic Ovary Syndrome (PCOS) Traits in a PCOS Mouse Model', Journal of the Endocrine Society, vol. 3, http://dx.doi.org/10.1210/js.2019-mon-231
    Journal articles | 2018
    Associate Professor Kirsty Walters
    Bertoldo MJ; Uddin GM; Youngson NA; Agapiou D; Walters KA; Sinclair DA; Morris MJ; Gilchrist RB, 2018, 'Multigenerational obesity-induced perturbations in oocyte-secreted factor signalling can be ameliorated by exercise and nicotinamide mononucleotide.', Hum Reprod Open, vol. 2018, pp. hoy010 - hoy010, http://dx.doi.org/10.1093/hropen/hoy010
    Journal articles | 2018
    Associate Professor Kirsty Walters
    Walters KA; Gilchrist RB; Ledger WL; Teede HJ; Handelsman DJ; Campbell RE, 2018, 'New Perspectives on the Pathogenesis of PCOS: Neuroendocrine Origins', Trends in Endocrinology and Metabolism, vol. 29, pp. 841 - 852, http://dx.doi.org/10.1016/j.tem.2018.08.005
    Journal articles | 2018
    Associate Professor Kirsty Walters
    Bertoldo MJ; Walters KA; Ledger WL; Gilchrist RB; Mermillod P; Locatelli Y, 2018, 'In-vitro regulation of primordial follicle activation: challenges for fertility preservation strategies', Reproductive BioMedicine Online, vol. 36, pp. 491 - 499, http://dx.doi.org/10.1016/j.rbmo.2018.01.014
    Journal articles | 2018
    Associate Professor Kirsty Walters
    Walters KA; Bertoldo MJ; Handelsman DJ, 2018, 'Evidence from animal models on the pathogenesis of PCOS', Best Practice and Research: Clinical Endocrinology and Metabolism, vol. 32, pp. 271 - 281, http://dx.doi.org/10.1016/j.beem.2018.03.008
    Journal articles | 2018
    Associate Professor Kirsty Walters
    Walters KA; Edwards MC; Tesic D; Caldwell ASL; Jimenez M; Smith JT; Handelsman DJ, 2018, 'The Role of Central Androgen Receptor Actions in Regulating the Hypothalamic-Pituitary-Ovarian Axis', Neuroendocrinology, vol. 106, pp. 389 - 400, http://dx.doi.org/10.1159/000487762
    Journal articles | 2018
    Associate Professor Kirsty Walters
    Walters KA; Handelsman DJ, 2018, 'Role of androgens in the ovary', Molecular and Cellular Endocrinology, vol. 465, pp. 36 - 47, http://dx.doi.org/10.1016/j.mce.2017.06.026
    Journal articles | 2018
    Associate Professor Kirsty Walters
    Upton DH; Walters KA; McTavish KJ; Holt J; Handelsman DJ; Allan CM, 2018, 'Reproductive failure in mice expressing transgenic follicle-stimulating hormone is not caused by loss of oocyte quality', Biology of Reproduction, vol. 98, pp. 491 - 500, http://dx.doi.org/10.1093/biolre/ioy015
    Journal articles | 2017
    Associate Professor Kirsty Walters
    Rodgers RJ; Reid GD; Koch J; Deans R; Ledger WL; Friedlander M; Gilchrist RB; Walters KA; Abbott JA, 2017, 'The safety and efficacy of controlled ovarian hyperstimulation for fertility preservation in women with early breast cancer: A systematic review', Human Reproduction, vol. 32, pp. 1033 - 1045, http://dx.doi.org/10.1093/humrep/dex027
    Journal articles | 2017
    Associate Professor Kirsty Walters
    Caldwell ASL; Edwards MC; Desai R; Jimenez M; Gilchrist RB; Handelsman DJ; Walters KA, 2017, 'Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome', Proceedings of the National Academy of Sciences of the United States of America, vol. 114, pp. E3334 - E3343, http://dx.doi.org/10.1073/pnas.1616467114
    Journal articles | 2017
    Associate Professor Kirsty Walters
    Camlin NJ; Jarnicki AG; Vanders RL; Walters KA; Hansbro PM; McLaughlin EA; Holt JE, 2017, 'Grandmaternal smoke exposure reduces female fertility in a murine model, with great-grandmaternal smoke exposure unlikely to have an effect', Human Reproduction, vol. 32, pp. 1270 - 1281, http://dx.doi.org/10.1093/humrep/dex073
    Journal articles | 2017
    Associate Professor Kirsty Walters
    Walters KA; Edwards MC; Jimenez M; Handelsman DJ; Allan CM, 2017, 'Subfertility in androgen-insensitive female mice is rescued by transgenic FSH', Reproduction, Fertility and Development, vol. 29, pp. 1426 - 1434, http://dx.doi.org/10.1071/RD16022
    Journal articles | 2016
    Associate Professor Kirsty Walters
    Wang X; Gook DA; Walters KA; Anazodo A; Ledger WL; Gilchrist RB, 2016, 'Improving fertility preservation for girls and women by coupling oocyte in vitro maturation with existing strategies', Women's Health, vol. 12, pp. 275 - 278, http://dx.doi.org/10.2217/whe-2016-0019
    Journal articles | 2016
    Associate Professor Kirsty Walters
    Walters KA; Simanainen U; Gibson DA, 2016, 'Androgen action in female reproductive physiology', Current Opinion in Endocrinology, Diabetes and Obesity, vol. 23, pp. 291 - 296, http://dx.doi.org/10.1097/MED.0000000000000246
    Journal articles | 2016
    Associate Professor Kirsty Walters
    Solon-Biet SM; Cogger VC; Pulpitel T; Heblinski M; Wahl D; McMahon AC; Warren A; Durrant-Whyte J; Walters KA; Krycer JR; Ponton F; Gokarn R; Wali JA; Ruohonen K; Conigrave AD; James DE; Raubenheimer D; Morrison CD; Le Couteur DG; Simpson SJ, 2016, 'Defining the Nutritional and Metabolic Context of FGF21 Using the Geometric Framework', Cell Metabolism, vol. 24, pp. 555 - 565, http://dx.doi.org/10.1016/j.cmet.2016.09.001
    Journal articles | 2016
    Associate Professor Kirsty Walters
    Shankara-Narayana N; Zawada S; Walters KA; Desai R; Marren A; Handelsman DJ, 2016, 'Accuracy of a Direct Progesterone Immunoassay', JOURNAL OF APPLIED LABORATORY MEDICINE, vol. 1, pp. 294 - 299, http://dx.doi.org/10.1373/jalm.2016.020123
    Journal articles | 2016
    Associate Professor Kirsty Walters
    Walters KA; Handelsman DJ, 2016, 'Androgen receptor splice variants and polycystic ovary syndrome: Cause or effect?', Asian Journal of Andrology, vol. 18, pp. 442 - 443, http://dx.doi.org/10.4103/1008-682X.161600
    Journal articles | 2016
    Associate Professor Kirsty Walters
    Walters KA, 2016, 'Androgens in polycystic ovary syndrome: Lessons from experimental models', Current Opinion in Endocrinology, Diabetes and Obesity, vol. 23, pp. 257 - 263, http://dx.doi.org/10.1097/MED.0000000000000245
    Journal articles | 2016
    Associate Professor Kirsty Walters
    Upton DH; Walters KA; Allavena RE; Jimenez M; Desai R; Handelsman DJ; Allan CM, 2016, 'Global or Granulosa Cell-Specific Pten Mutations in Combination with Elevated FSH Levels Fail to Cause Ovarian Tumours in Mice', Hormones and Cancer, vol. 7, pp. 316 - 326, http://dx.doi.org/10.1007/s12672-016-0272-3
    Journal articles | 2015
    Associate Professor Kirsty Walters
    Walters KA, 2015, 'Role of androgens in normal and pathological ovarian function', Reproduction, vol. 149, pp. R193 - R218, http://dx.doi.org/10.1530/REP-14-0517
    Journal articles | 2015
    Associate Professor Kirsty Walters
    Caldwell ASL; Eid S; Kay CR; Jimenez M; McMahon AC; Desai R; Allan CM; Smith JT; Handelsman DJ; Walters KA, 2015, 'Haplosufficient genomic androgen receptor signaling is adequate to protect female mice from induction of polycystic ovary syndrome features by prenatal hyperandrogenization', Endocrinology, vol. 156, pp. 1441 - 1452, http://dx.doi.org/10.1210/en.2014-1887
    Journal articles | 2015
    Associate Professor Kirsty Walters
    Solon-Biet SM; Walters KA; Simanainen UK; McMahon AC; Ruohonen K; Ballard JWO; Raubenheimer D; Handelsman DJ; Couteur DGL; Simpson SJ, 2015, 'Macronutrient balance, reproductive function, and lifespan in aging mice', Proceedings of the National Academy of Sciences of the United States of America, vol. 112, pp. 3481 - 3486, http://dx.doi.org/10.1073/pnas.1422041112
    Journal articles | 2015
    Associate Professor Kirsty Walters
    Handelsman DJ; Jimenez M; Singh GKS; Spaliviero J; Desai R; Walters KA, 2015, 'Measurement of testosterone by immunoassays and mass spectrometry in mouse serum, testicular, and ovarian extracts', Endocrinology, vol. 156, pp. 400 - 405, http://dx.doi.org/10.1210/en.2014-1664
    Journal articles | 2015
    Associate Professor Kirsty Walters
    Upton DH; Fuller ES; Colvin EK; Walters KA; Jimenez M; Desai R; Handelsman DJ; Howell VM; Allan CM, 2015, 'Granulosa Cell-Specific Brca1 Loss Alone or Combined with Trp53 Haploinsufficiency and Transgenic FSH Expression Fails to Induce Ovarian Tumors', Hormones and Cancer, vol. 6, pp. 142 - 152, http://dx.doi.org/10.1007/s12672-015-0222-5
    Journal articles | 2014
    Associate Professor Kirsty Walters
    Caldwell ASL; Middleton LJ; Jimenez M; Desai R; McMahon AC; Allan CM; Handelsman DJ; Walters KA, 2014, 'Characterization of reproductive, metabolic, and endocrine features of polycystic ovary syndrome in female hyperandrogenic mouse models', Endocrinology, vol. 155, pp. 3146 - 3159, http://dx.doi.org/10.1210/en.2014-1196
    Journal articles | 2014
    Associate Professor Kirsty Walters
    Gao YR; Walters KA; Desai R; Zhou H; Handelsman DJ; Simanainen U, 2014, 'Androgen receptor inactivation resulted in acceleration in pubertal mammary gland growth, upregulation of ERα expression, and Wnt/β-catenin signaling in female mice', Endocrinology, vol. 155, pp. 4951 - 4963, http://dx.doi.org/10.1210/en.2014-1226
    Journal articles | 2013
    Associate Professor Kirsty Walters
    Cheng XB; Jimenez M; Desai R; Middleton LJ; Joseph SR; Ning G; Allan CM; Smith JT; Handelsman DJ; Walters KA, 2013, 'Characterizing the neuroendocrine and ovarian defects of androgen receptor-knockout female mice', American Journal of Physiology - Endocrinology and Metabolism, vol. 305, http://dx.doi.org/10.1152/ajpendo.00263.2013
    Journal articles | 2012
    Associate Professor Kirsty Walters
    Walters KA; Middleton LJ; Joseph SR; Hazra R; Jimenez M; Simanainen U; Allan CM; Handelsman DJ, 2012, 'Targeted loss of androgen receptor signaling in murine granulosa cells of preantral and antral follicles causes female subfertility', Biology of Reproduction, vol. 87, http://dx.doi.org/10.1095/biolreprod.112.102012
    Journal articles | 2012
    Associate Professor Kirsty Walters
    Walters KA; Allan CM; Handelsman DJ, 2012, 'Rodent models for human polycystic ovary syndrome', Biology of Reproduction, vol. 86, http://dx.doi.org/10.1095/biolreprod.111.097808
    Journal articles | 2012
    Associate Professor Kirsty Walters
    Simanainen U; Gao YR; Walters KA; Watson G; Desai R; Jimenez M; Handelsman DJ, 2012, 'Androgen resistance in female mice increases susceptibility to DMBA-induced mammary tumors', Hormones and Cancer, vol. 3, pp. 113 - 124, http://dx.doi.org/10.1007/s12672-012-0107-9
    Journal articles | 2010
    Associate Professor Kirsty Walters
    Allan CM; McTavish KJ; Lamb S; Walters KA; Handelsman DJ, 2010, '125. ELEVATED FSH INCREASES PRIMORDIAL FOLLICLE RESERVE WITHOUT INCREASING PRIMORDIAL FOLLICLE FORMATION OR DECREASING OOCYTE QUALITY', Reproduction, Fertility and Development, vol. 22, pp. 43 - 43, http://dx.doi.org/10.1071/srb10abs125
    Journal articles | 2010
    Associate Professor Kirsty Walters
    Walters KA; Simanainen U; Handelsman DJ, 2010, 'Molecular insights into androgen actions in male and female reproductive function from androgen receptor knockout models', Human Reproduction Update, vol. 16, pp. 543 - 558, http://dx.doi.org/10.1093/humupd/dmq003
    Journal articles | 2010
    Associate Professor Kirsty Walters
    McNamara KM; Harwood DT; Simanainen U; Walters KA; Jimenez M; Handelsman DJ, 2010, 'Measurement of sex steroids in murine blood and reproductive tissues by liquid chromatography-tandem mass spectrometry', Journal of Steroid Biochemistry and Molecular Biology, vol. 121, pp. 611 - 618, http://dx.doi.org/10.1016/j.jsbmb.2010.02.001
    Journal articles | 2009
    Associate Professor Kirsty Walters
    Walters KA; McTavish KJ; Seneviratne MG; Jimenez M; McMahon AC; Allan CM; Salamonsen LA; Handelsman DJ, 2009, 'Subfertile female androgen receptor knockout mice exhibit defects in neuroendocrine signaling, intraovarian function, and uterine development but not uterine function', Endocrinology, vol. 150, pp. 3274 - 3282, http://dx.doi.org/10.1210/en.2008-1750
    Journal articles | 2008
    Associate Professor Kirsty Walters
    McTavish KJ; Walters KA; Handelsman DJ; Allan CM, 2008, '265. Increased FSH activity increases primordial follicle reserve and enhances preovulatory follicle survival in transgenic FSH female mice', Reproduction, Fertility and Development, vol. 20, pp. 65 - 65, http://dx.doi.org/10.1071/srb08abs265
    Journal articles | 2008
    Associate Professor Kirsty Walters
    Walters KA; Allan CM; Handelsman DJ, 2008, 'Androgen actions and the ovary', Biology of Reproduction, vol. 78, pp. 380 - 389, http://dx.doi.org/10.1095/biolreprod.107.064089
    Journal articles | 2007
    Associate Professor Kirsty Walters
    Walters KA; Allan CM; Jimenez M; Lim PR; Davey RA; Zajac JD; Illingworth P; Handelsman DJ, 2007, 'Female mice haploinsufficient for an inactivated androgen receptor (AR) exhibit age-dependent defects that resemble the AR null phenotype of dysfunctional late follicle development, ovulation, and fertility', Endocrinology, vol. 148, pp. 3674 - 3684, http://dx.doi.org/10.1210/en.2007-0248
    Journal articles | 2007
    Associate Professor Kirsty Walters
    McTavish KJ; Jimenez M; Walters KA; Spaliviero J; Groome NP; Themmen AP; Visser JA; Handelsman DJ; Allan CM, 2007, 'Rising follicle-stimulating hormone levels with age accelerate female reproductive failure', Endocrinology, vol. 148, pp. 4432 - 4439, http://dx.doi.org/10.1210/en.2007-0046
    Journal articles | 2007
    Associate Professor Kirsty Walters
    Walters KA; Armstrong DG; Telfer EE, 2007, 'Bovine mural granulosa cells, and not the oocyte, are the major source of proteases capable of IGFBP-2 degradation', Animal Reproduction Science, vol. 98, pp. 365 - 370, http://dx.doi.org/10.1016/j.anireprosci.2006.04.047
    Journal articles | 2006
    Associate Professor Kirsty Walters
    Walters KA; Binnie JP; Campbell BK; Armstrong DG; Telfer EE, 2006, 'The effects of IGF-I on bovine follicle development and IGFBP-2 expression are dose and stage dependent', Reproduction, vol. 131, pp. 515 - 523, http://dx.doi.org/10.1530/rep.1.00682
    Journal articles | 2003
    Associate Professor Kirsty Walters
    Thomas FH; Walters KA; Telfer EE, 2003, 'How to make a good oocyte: An update on in-vitro models to study follicle regulation', Human Reproduction Update, vol. 9, pp. 541 - 555, http://dx.doi.org/10.1093/humupd/dmg042
  • Working Papers | 2019
    Associate Professor Kirsty Walters
    Bertoldo M; Listijono D; Ho W-HJ; Riepsamen A; Jin X; Selesniemi K; Goss D; Mahbub S; Campbell J; Habibalahi A; Loh W-GN; Youngson N; Maniam J; Wong ASA; Richani D; Li C; Zhao Y; Marinova M; Kim L-J; Lau L; Wu R; Mikolaizak S; Araki T; Le Couteur D; Turner N; Morris M; Walters K; Goldys E; O’Neill C; Gilchrist R; Sinclair D; Homer H; Wu L, 2019, NAD+repletion rescues female fertility during reproductive ageing, http://dx.doi.org10.1101/721985
    Conference Papers | 2016
    Associate Professor Kirsty Walters
    Walters K; Caldwell A; Edwards M; Handelsman D, 2016, 'Unravelling the role of extra- and intra-ovarian androgen receptor-mediated mechanisms driving the development of ovarian polycystic ovary syndrome (PCOS) traits', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, pp. 416 - 417, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000453583904008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Associate Professor Kirsty Walters
    Narayana NS; Walters KA; Zawada S; Bonifacio M; Marren A; Handelsman DJ, 2015, 'Accuracy of direct progesterone immunoassay vs liquid chromatography mass spectrometry', in CLINICAL ENDOCRINOLOGY, WILEY, Adelaide, AUSTRALIA, Vol. 84, pp. 40 - 40, presented at Annual Scientific Meeting of the Endocrine-Society-of-Australia, Adelaide, AUSTRALIA, 23 August 2015 - 26 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000372310400106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2015
    Associate Professor Kirsty Walters
    Narayana N; Walters K; Zawada S; Bonifacio M; Marren A; Handelsman DJ, 2015, 'Accuracy of direct progesterone immunoassay vs liquid chromatography mass spectrometry', in Clinical Endocrinology, Wiley, Adelaide, AUSTRALIA, presented at Annual Scientific Meeting of the Endocrine-Society-of-Australia, Adelaide, AUSTRALIA, 23 August 2015 - 26 August 2015
    Conference Abstracts | 2010
    Associate Professor Kirsty Walters
    Simanainen U; Walters KA; Watson G; Gao YR; Handelsman DJ, 2010, 'Androgen Receptor Is a Tumor Suppressor in DMBA-Induced Mammary Tumors.', in ENDOCRINE REVIEWS, ENDOCRINE SOC, San Diego, CA, Vol. 31, presented at 92nd Meeting and Expo of the Endocrine Society (ENDO 2010), San Diego, CA, 19 June 2010 - 22 June 2010, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000281989401057&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2010
    Associate Professor Kirsty Walters
    Simanainen U; Walters K; Watson G; Gao G; Handelsman DJ, 2010, 'Androgen Receptor Is a Tumor Suppressor in DMBA-Induced Mammary Tumors', in Endocrine Reviews, Oxford University Press (OUP), San Diego, CA, presented at 92nd Meeting and Expo of the Endocrine Society (ENDO 2010), San Diego, CA, 19 June 2010 - 22 June 2010
    Conference Papers | 2004
    Associate Professor Kirsty Walters
    Walters K; Binnie J; Campbell K; Armstrong D; Telfer E, 2004, 'The effects of IGF-1 on follicle development and IGFBP-2 expression in bovine antral follicles in vitro.', in Biology of Reproduction, Univ British Columbia, Vancouver, CANADA, presented at 37th Annual Meeting of the Society-for-the-Study-of-Reproduction, Univ British Columbia, Vancouver, CANADA, 01 August 2004 - 04 August 2004

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