Dr Krista Siefried
Senior Research Fellow

Dr Krista Siefried

RN; BSc; GCert Continuing Care; GDip Coronary Care; PhD

Medicine & Health
National Drug & Alcohol Research Centre

Clinical Research Lead and Deputy Director, the National Centre for Clinical Research on Emerging Drugs (NCCRED). Senior Lecturer, UNSW National Drug and Alcohol Research Centre (NDARC), and St Vincent's Hospital Sydney Centre for Applied Medical Research (SVHS AMR) and Alcohol and Drug Service.

Dr Siefried is an emerging leader in clinical research and clinical trials in populations at risk of harms due to substance use disorders. In her role as Clinical Research Lead and Deputy Director at NCCRED her extensive HIV, Infectious Diseases, Drug and Alcohol, and Public Health experience enable her to direct a program of clinical research and translation; facilitate the establishment of a national clinical research network; and oversee the NCCRED clinical research capacity building grants, seed funding grants, and clinical research fellowships and scholarships. 

Dr Siefried has extensive experience in clinical research, healthcare, and clinical project management. Prior leadership roles include: Senior Clinical Project Manager (SVHS AMR); Clinical Research Manager (SVHS AMR Clinical Research Program); and Nurse Unit Manager (Immunology and Infectious Diseases). Prior clinical experience includes Research Nurse and Clinical Trials Coordinator; Registered Nurse / Clinical Nurse Specialist; Heart/Lung Transplant Coordinator; ICU and CCU Registered Nurse (in Australia and Canada). 

Broad clinical research interests include comorbidities and treatment outcomes in people living with HIV, and pharmacotherapy for people with methamphetamine dependence.

Phone
+61 2 9065 7808
  • Journal articles | 2022
    Acheson LS; Ezard N; Lintzeris N; Dunlop A; Brett J; Rodgers C; Gill A; Christmass M; McKetin R; Farrell M; Shoptaw S; Siefried KJ, 2022, 'Trial protocol of an open label pilot study of lisdexamfetamine for the treatment of acute methamphetamine withdrawal', PloS one, vol. 17, pp. e0275371, http://dx.doi.org/10.1371/journal.pone.0275371
    Journal articles | 2022
    Acheson LS; Williams BH; Farrell M; McKetin R; Ezard N; Siefried KJ, 2022, 'Pharmacological treatment for methamphetamine withdrawal: A systematic review and meta-analysis of randomised controlled trials', Drug and Alcohol Review, http://dx.doi.org/10.1111/dar.13511
    Journal articles | 2022
    Brett J; Siefried KJ; Healey A; Harrod ME; Franklin E; Barratt MJ; Masters J; Nguyen L; Adiraju S; Gerber C, 2022, 'Wastewater analysis for psychoactive substances at music festivals across New South Wales, Australia in 2019–2020', Clinical Toxicology, vol. 60, pp. 440 - 445, http://dx.doi.org/10.1080/15563650.2021.1979233
    Journal articles | 2022
    Freeman G; Siefried KJ; Roberts DM; Rodgers C; Nic Ionmhain U; Ramanathan J; Ezard N; Brett J, 2022, 'Phenobarbital to manage severe gamma-hydroxybutyrate withdrawal: A case series', Drug and Alcohol Review, vol. 41, pp. S63 - S64, http://dx.doi.org/10.1111/dar.13556
    Journal articles | 2022
    Freestone J; Bourne A; Layard E; Prestage G; Murray J; Siefried KJ, 2022, 'Playing at the edges, navigating sexual boundaries, and narrating sexual distress; Practices and perspectives of sexuality and gender diverse people who use GHB', International Journal of Drug Policy, vol. 108, pp. 103811, http://dx.doi.org/10.1016/j.drugpo.2022.103811
    Journal articles | 2022
    Freestone J; Prestage G; Bourne A; Ezard N; Race K; Nedanoski A; Murray J; Siefried KJ, 2022, 'Controlling for pleasure and risk: The experiences of sexuality and gender diverse people who use GHB', International Journal of Drug Policy, vol. 105, pp. 103747, http://dx.doi.org/10.1016/j.drugpo.2022.103747
    Journal articles | 2022
    Freestone J; Siefried KJ; Prestage G; Hammoud M; Molyneux A; Bourne A, 2022, 'Individual level peer interventions for gay and bisexual men who have sex with men between 2000 and 2020: A scoping review', PLoS ONE, vol. 17, http://dx.doi.org/10.1371/journal.pone.0270649
    Journal articles | 2022
    Healey A; Siefried KJ; Harrod ME; Franklin E; Peacock A; Barratt MJ; Brett J, 2022, 'Correlates of higher-risk drug-related behaviours at music festivals in New South Wales, Australia', Drug and Alcohol Review, vol. 41, pp. 320 - 329, http://dx.doi.org/10.1111/dar.13404
    Journal articles | 2022
    Page R; Healey A; Siefried KJ; Harrod ME; Franklin E; Peacock A; Barratt MJ; Brett J, 2022, 'Barriers to help-seeking among music festival attendees in New South Wales, Australia', Drug and Alcohol Review, vol. 41, pp. 1322 - 1330, http://dx.doi.org/10.1111/dar.13479
    Journal articles | 2022
    Siefried KJ; Ezard N; Christmass M; Haber P; Ali R, 2022, 'A clinical research priority setting study for issues related to the use of methamphetamine and emerging drugs of concern in Australia', Drug and Alcohol Review, vol. 41, pp. 309 - 319, http://dx.doi.org/10.1111/dar.13350
    Journal articles | 2021
    Acheson LS; Siefried KJ; Clifford B; Murray E; Steele M; Clague L; Malone V; Roberts DM; Ferguson LJ; Matthews GV; Ezard N, 2021, 'One-third of people who inject drugs are at risk of incomplete treatment for Staphylococcus aureus bacteraemia: a retrospective medical record review', International Journal of Infectious Diseases, vol. 112, pp. 63 - 65, http://dx.doi.org/10.1016/j.ijid.2021.09.012
    Journal articles | 2021
    Ezard N; Clifford B; Dunlop A; Bruno R; Carr A; Liu Z; Siefried KJ; Lintzeris N, 2021, 'Safety and tolerability of oral lisdexamfetamine in adults with methamphetamine dependence: A phase-2 dose-escalation study', BMJ Open, vol. 11, pp. e044696, http://dx.doi.org/10.1136/bmjopen-2020-044696
    Journal articles | 2021
    Lee E; Mao L; de Wit J; Rule J; Carr A; Siefried KJ, 2021, 'Impact of the removal of patient co-payments for antiretroviral therapy (ART) on out-of-pocket expenditure, adherence and virological failure among Australian adults living with HIV', HEALTH POLICY, vol. 125, pp. 1131 - 1139, http://dx.doi.org/10.1016/j.healthpol.2021.07.002
    Journal articles | 2020
    Siefried KJ; Acheson LS; Lintzeris N; Ezard N, 2020, 'Pharmacological treatment of methamphetamine/amphetamine dependence: a systematic review', CNS Drugs, http://dx.doi.org/10.1007/s40263-020-00711-x
    Journal articles | 2019
    Siefried KJ; Kerr S; Richardson R; Mao L; Rule J; McAllister J; De Wit J; Carr A, 2019, 'Socioeconomic and psychosocial factors are associated with poor treatment outcomes in Australian adults living with HIV: A case-control study', Sexual Health, vol. 16, pp. 548 - 553, http://dx.doi.org/10.1071/SH18138
    Journal articles | 2018
    Siefried KJ; Mao L; Cysique LA; Rule J; Giles ML; Smith DE; McMahon J; Read TR; Ooi C; Tee BK; Bloch M; De Wit J; Carr A, 2018, 'Concomitant medication polypharmacy, interactions and imperfect adherence are common in Australian adults on suppressive antiretroviral therapy', AIDS, vol. 32, pp. 35 - 48, http://dx.doi.org/10.1097/QAD.0000000000001685
    Journal articles | 2017
    Siefried KJ; Mao L; Kerr S; Cysique LA; Gates TM; McAllister J; Maynard A; De Wit J; Carr A, 2017, 'Socioeconomic factors explain suboptimal adherence to antiretroviral therapy among HIV-infected Australian adults with viral suppression', PLoS ONE, vol. 12, http://dx.doi.org/10.1371/journal.pone.0174613
    Journal articles | 2016
    Gates TM; Cysique LA; Siefried KJ; Chaganti J; Moffat KJ; Brew BJ, 2016, 'Maraviroc-intensified combined antiretroviral therapy improves cognition in virally suppressed HIV-associated neurocognitive disorder', AIDS, vol. 30, pp. 591 - 600, http://dx.doi.org/10.1097/QAD.0000000000000951
    Journal articles | 2014
    Lu GM; Brew BJ; Siefried KJ; Draper B; Cysique LA, 2014, 'Is the HIV dementia scale a reliable tool for assessing HIV-relatedneurocognitive decline?', Journal of AIDS and Clinical Research, vol. 5, http://dx.doi.org/10.4172/2155-6113.1000269
  • Conference Posters | 2022
    Acheson L; Ezard N; Lintzeris N; Dunlop A; Brett J; Rodgers C; Gill A; Christmass M; McKetin R; Farrell M; Shoptaw S; Siefried K, 2022, 'The Safety and Feasibility of Lisdexamfetamine for the Treatment of Acute Methamphetamine Withdrawal: Preliminary Results of an Open Label Pilot Study', Minneapolis, USA, presented at The College on Problems of Drug Dependence 84th Annual Scientific Meeting, Minneapolis, USA, 11 June 2022 - 15 June 2022, https://d2p55c5k0gw6a2.cloudfront.net/wp-content/uploads/2022/07/2022-CPDD-Abstract-Book.pdf
    Conference Posters | 2022
    Aung HL; Gates TM; Mao L; Brew B; Siefried K; Carr A; Cysique L, 2022, 'Clinically significant cognitive decline is uncommon in virally suppressed HIV. However, there was a signal for abnormal aging and complex impact of psychosocial and socio-economic factors on longitudinal cognitive performance', Virtual, presented at Conference on Retroviruses and Opportunistic Infections, Virtual, 14 February 2022 - 16 February 2022
    Conference Presentations | 2022
    Bascombe F; Siefried K, 2022, 'AOD telephone counselling toolkit', presented at Drug and Alcohol Nurses Australasia Conference 2022, Adelaide, 03 August 2022 - 05 August 2022
    Conference Presentations | 2022
    Bascombe F; Siefried K, 2022, 'Methamphetamine treatment landscape', presented at Drug and Alcohol Nurses Australasia Conference 2022, Adelaide, 03 August 2022 - 05 August 2022
    Preprints | 2022
    Clifford B; Van Gordon K; Magee F; Malone V; Siefried K; Graham D; Ezard N, 2022, “There’s a big tag on my head”: exploring barriers to treatment seeking with women who use methamphetamine in Sydney, Australia, http://dx.doi.org/10.1101/2022.08.01.22278295
    Conference Presentations | 2022
    Siefried K; Acheson L; Williams B; Farrell M; McKetin R; Ezard N, 2022, 'OUTCOMES AND MEASURES USED IN RANDOMISED CONTROLLED TRIALS EXAMINING PHARMACOTHERAPIES FOR THE TREATMENT OF METHAMPHETAMINE WITHDRAWAL: RESULTS OF A SYSTEMATIC REVIEW', presented at The College on Problems of Drug Dependence 84th Annual Scientific Meeting, Minneapolis, USA, 11 June 2022 - 15 July 2022, https://d2p55c5k0gw6a2.cloudfront.net/wp-content/uploads/2022/07/2022-CPDD-Abstract-Book.pdf
    Conference Presentations | 2022
    Williams BH; Acheson LS; Farrell M; McKetin R; Ezard N; Siefried K, 2022, 'Pharmacological treatment for methamphetamine withdrawal: a systematic review and meta-analysis of randomised controlled trials', presented at RANZCP 2022 Congress, Sydney, 15 May 2022 - 19 May 2022, http://dx.doi.org/10.1177/00048674221088686
    Conference Abstracts | 2022
    Williams BH; Acheson LS; Farrell M; McKetin R; Ezard N; Siefried KJ, 2022, 'PHARMACOLOGICAL TREATMENT FOR METHAMPHETAMINE WITHDRAWAL: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMISED CONTROLLED TRIALS', in AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, SAGE PUBLICATIONS LTD, Vol. 56, pp. 208 - 209, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000792769900489&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Posters | 2021
    Acheson L; Williams BHM; Farrell M; McKetin R; Ezard N; Siefried K, 2021, 'Pharmacological treatment for methamphetamine withdrawal: a systematic review and meta-analysis of randomised controlled trials', Virtual, presented at The APSAD Scientific Drug and Alcohol Conference, Virtual, 07 November 2021 - 10 November 2021, http://dx.doi.org/10.1111/dar.13384
    Conference Posters | 2021
    Black E; Deacon RM; Mills L; Mammen K; Dunlop A; Ezard N; Montebello M; Bruno R; Shakeshaft A; Farrell M; Holmes J; Reid D; Childs S; Siefried K; Cretikos M; Lintzeris N, 2021, 'Starting treatment in public drug and alcohol services in New South Wales: What can electronic medical records tell us about amphetamine type stimulant use?', Virtual, presented at The APSAD Scientific Drug and Alcohol Conference, Virtual, 07 November 2021 - 10 November 2021, http://dx.doi.org/10.1111/dar.13384
    Conference Presentations | 2021
    Freestone J; Siefried KJ; Bourne A; Hammoud M; Prestage G, 2021, 'Peer-led interventions addressing health and wellbeing for gay and bisexual men between 2000 and 2020: A scoping review', presented at Joint Australasian Sexual Health, HIV and AIDS Conferences, Virtual, 06 September 2021 - 09 September 2021
    Conference Presentations | 2021
    Harris O; Siefried K; Chiew A; Aguirrebarrena G; Roberts D; Brett J, 2021, 'Gamma-hydroxybutyrate Overdose in Inner-Sydney Emergency Departments: a retrospective review', presented at ASCEPT Annual Scientific Meeting, Virtual, 29 November 2021 - 02 December 2021
    Conference Presentations | 2021
    Healey A; Siefried K; Harrod ME; Franklin E; Peacock A; Barratt M; Brett J, 2021, 'Correlates of higher risk drug related behaviours at music festivals in New South Wales, Australia', presented at The APSAD Scientific Drug and Alcohol Conference, Virtual, 07 November 2021 - 10 November 2021, http://dx.doi.org/10.1111/dar.13384
    Conference Posters | 2021
    May R; Ezard N; Siefried K; Bruno R, 2021, 'Neurocognitive changes in adults with methamphetamine dependence treated with lisdexamfetamine compared with those with additional positive screening for childhood ADHD', presented at International Medicine in Addiction Conference, 26 February 2021 - 28 February 2021
    Conference Presentations | 2021
    Page RMS; Healey A; Siefried K; Harrod M; Franklin E; Barratt M; Peacock A; Brett J, 2021, 'Barriers to seeking help among music festival attendees in New South Wales, Australia', presented at The APSAD Scientific Drug and Alcohol Conference, Virtual, 07 November 2021 - 10 November 2021, http://dx.doi.org/10.1111/dar.13384
    Conference Posters | 2021
    Siefried K; Acheson L; Dunlop A; Lintzeris N; Christmass M; Bonomo Y; Arunogiri S; Hayllar J; Ezard N, 2021, 'A clinical research network approach to a trial of lisdexamfetamine for the treatment of acute methamphetamine withdrawal', Virtual, presented at The APSAD Scientific Drug and Alcohol Conference, Virtual, 07 November 2021 - 10 November 2021, http://dx.doi.org/10.1111/dar.13384
    Conference Presentations | 2021
    Siefried K; Arunogiri S; Brett J; McKetin R; Acheson LS; Knock E; Farrell M; Dunlop A; Lintzeris N; Ezard N, 2021, 'The future of pharmacotherapy clinical trials in Australia: the OLAM trial; the MOXY trial; the PSIMA trial; the TINA trial', presented at The APSAD Scientific Drug and Alcohol Conference, Virtual, 07 November 2021 - 10 November 2021, http://dx.doi.org/10.1111/dar.13384
    Conference Posters | 2021
    Siefried K; Ezard N; Christmass M; Hayllar J; Ali R, 2021, 'Towards an Australian clinical research network for methamphetamine and emerging drugs - outcomes of the National Centre for Clinical Research on Emerging Drugs Methamphetamine and Emerging Drugs Clinical Research Network Working Group', Virtual, presented at The APSAD Scientific Drug and Alcohol Conference, Virtual, 07 November 2021 - 10 November 2021, http://dx.doi.org/10.1111/dar.13384
    Conference Presentations | 2021
    Siefried K; McKetin R; Bedi G; Brett J; Arunogiri S; Dunlop A; Lintzeris N; Ezard N, 2021, 'Symposium: An update on pharmacotherapy trials for substance use disorder - methamphetamine type and withdrawal in Australia', presented at The APSAD Scientific Drug and Alcohol Conference, 07 November 2021 - 10 November 2021, http://dx.doi.org/10.1111/dar.13384
    Preprints | 2020
    Ezard N; Clifford B; Dunlop A; Bruno R; Carr A; Liu Z; Siefried K; Lintzeris N, 2020, Safety and tolerability of oral lisdexamfetamine in adults with methamphetamine dependence: a phase-2 dose-escalation study, http://dx.doi.org/10.21203/rs.3.rs-30957/v1
    Conference Abstracts | 2019
    Acheson LS; Murray E; Clifford B; Siefried KJ; Matthews GV; Ezard N, 2019, 'OPTIMISING CARE FOR PEOPLE WHO INJECT DRUGS: A RETROSPECTIVE MEDICAL RECORD REVIEW OF STAPHYLOCOCCUS AUREUS BACTERAEMIA TREATMENT', in DRUG AND ALCOHOL REVIEW, WILEY, Vol. 38, pp. S22 - S23, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000494890100057&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Acheson LS; Murray E; Clifford B; Siefried KJ; Matthews GV; Ezard N, 2019, 'Optimising care for people who inject drugs: A retrospective medical record review of staphylococcus aureus bactaraemia treatment', in Drug and Alcohol Review, Wiley, Hobart, Australia, Vol. 38, presented at Australasian Professional Society on Alcohol and other Drugs (APSAD) Scientific Conference, Hobart, Australia, 10 November 2019 - 13 November 2019, http://dx.doi.org/10.1111/dar.12991
    Conference Abstracts | 2019
    Black E; Deacon RM; Mills L; Dunlop A; Ezard N; Bruno R; Shakeshaft A; Farrell M; Holmes J; Cretikos MA; Montebello M; Reid D; Childs S; Siefried KJ; Mammen K; Lintzeris N, 2019, 'Characteristics and treatment outcomes of the drug treatment population in New South Wales: Focus on amphetamine type stimulants', in Drug and Alcohol Review, Wiley, Hobart, Australia, Vol. 38, presented at Australasian Professional Society on Alcohol and other Drugs (APSAD) Scientific Conference, Hobart, Australia, 10 November 2019 - 13 November 2019, http://dx.doi.org/10.1111/dar.12991
    Conference Abstracts | 2019
    Black E; Deacon RM; Mills L; Dunlop AJ; Ezard N; Bruno R; Shakeshaft A; Farrell M; Holmes J; Cretikos MA; Montebello M; Reid D; Childs S; Siefried KJ; Mammen K; Lintzeris N, 2019, 'CHARACTERISTICS AND TREATMENT OUTCOMES OF THE DRUG TREATMENT POPULATION IN NEW SOUTH WALES: FOCUS ON AMPHETAMINE TYPE STIMULANTS', in DRUG AND ALCOHOL REVIEW, WILEY, Vol. 38, pp. S27 - S28, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000494890100070&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Posters | 2019
    Carr M; Martin SJ; Foster R; Finlayson R; Rule J; Smith DE; de Wit J; Carr A; Siefried KJ, 2019, 'STI incidence and risk factors in HIV-infected adults on antiretrovrial therapy (ART) in the PAART study', Perth, Australia, presented at Joint Australasian Sexual Health and HIV&AIDS Conference, Perth, Australia, 16 September 2019 - 19 September 2019
    Conference Presentations | 2019
    Ezard N; Acheson LS; Siefried KJ; Leicester OM; Rodgers C; Malone V; Clifford B; Bruno R, 2019, 'Substance use sex index (SUSI): A new behaviour change assessment tool', presented at Lisbon Addictions 2019: The Third European Conference on Addictive Behaviours and Dependencies, Lisbon, Portugal, 23 October 2019 - 25 October 2019
    Conference Posters | 2019
    Ezard N; Dunlop AJ; Clifford B; Bruno R; Siefried KJ; Carr A; Lintzeris N, 2019, 'Safety of oral lisdexamfetamine in adults with methamphetamine dependence: a dose-escalating phase-2 study', San Antonio, Texas, USA, presented at The College on Problems of Drug Dependence 81st Annual Scientific Meeting, San Antonio, Texas, USA, 15 June 2019 - 19 July 2019
    Conference Posters | 2019
    Ezard N; Siefried KJ; Peacock A, 2019, 'Developing a national prompt response network for Australia', Amsterdam, The Netherlands, presented at The 11th International Conference on Nightlife, Substance Use and Related Health Issues, Amsterdam, The Netherlands, 15 May 2019 - 17 May 2019
    Reports | 2019
    Lintzeris N; Sunjic S; Demirkol A; Branezac M; Ezard N; Siefried K; Acheson LS; Bascombe F; Tremonti C; Haber P, 2019, Management of withdrawal from alcohol and other drugs: an evidence check rapid review brokered by the Sax Institute for the NSW Ministry of Health, Sax Institute
    Conference Abstracts | 2019
    Nguyen QA; Middleton P; Herman D; Li K; Grundy E; Li E; Siefried KJ; Malone V; Kay-Lambkin F; Ezard N, 2019, 'What's in an app? Incorporating an automated consent procedure to recruit those who use methamphetamine to a harm reduction and early intervention smartphone-based application clinical trial', in Drug and Alcohol Review, Wiley, Hobart, Australia, Vol. 38, presented at Australasian Professional Society on Alcohol and other Drugs (APSAD) Scientific Conference, Hobart, Australia, 10 November 2019 - 13 November 2019, http://dx.doi.org/10.1111/dar.12991
    Conference Abstracts | 2019
    Sandra S; Demerikol A; Branezac M; Ezard N; Siefried KJ; Acheson LS; Bascombe F; Tremonti C; Haber P; Lintzeris N, 2019, 'Are we detoxing the right people, in the right setting and in the right way? A rapid review of the literature on withdrawal management', in Drug and Alcohol Review, Wiley, Hobart, Australia, Vol. 38, presented at Australasian Professional Society on Alcohol and other Drugs (APSAD) Scientific Conference, Hobart, Australia, 10 November 2019 - 13 November 2019, http://dx.doi.org/10.1111/dar.12991
    Conference Presentations | 2019
    Siefried K; Nguyen Q; Ezard N, 2019, 'An Australian clinical research priority setting study for substance use disorder due to methamphetamine and emerging drugs of concern', presented at Lisbon Addictions 2019: The Third European Conference on Addictive Behaviours and Dependencies, Lisbon, Portugal, 23 October 2019 - 25 October 2019
    Conference Abstracts | 2019
    Siefried KJ; Nguyen QA; Ezard N; Christmass M; Ali R, 2019, 'A rapid clinical research priority setting study for substance use disorder due to methamphetamine and emerging drugs of concern in Australia', in Drug and Alcohol Review, Wiley, Hobart, Australia, Vol. 38, presented at Australasian Professional Society on Alcohol and other Drugs (APSAD) Scientific Conference, Hobart, Australia, 10 November 2019 - 13 November 2019, http://dx.doi.org/10.1111/dar.12991
    Conference Posters | 2019
    Siefried KJ; Peacock A; Ezard N, 2019, 'Towards a prompt response network for Australia: coordinated and rapid communication of information about events of concerns related to emerging substances', Maastricht, The Netherlands, presented at Sixth International Conference on Novel Psychoactive Substances, Maastricht, The Netherlands, 08 April 2019 - 09 April 2019
    Theses / Dissertations | 2018
    Siefried KJ, 2018, Antiretroviral therapy and treatment cascade outcomes in a cohort of adults living with HIV in Australia
    Conference Posters | 2018
    Siefried KJ; Mao L; Riches S; Kerr S; Rule J; McAllister J; de Wit J; Carr A, 2018, 'Failure of antiretroviral therapy (ART) in adults in Australia is mainly due to ART toxicity (updated report with predictors of ART failure)', Amsterdam, the Netherlands, presented at 22nd International AIDS Conference, Amsterdam, the Netherlands, 23 July 2018 - 27 July 2018
    Conference Posters | 2018
    Siefried KJ; Mao L; Riches S; Kerr S; Rule J; de Wit J; Carr A, 2018, 'Failure of antiretroviral therapy (ART) in adults in Australia is mainly due to ART toxicity (an updated report with predictors of ART failure)', Sydney, Australia, presented at The Australasian HIV&AIDS Conference, Sydney, Australia, 24 September 2018 - 26 September 2018
    Conference Presentations | 2018
    Siefried KJ; Mao L; Rule J; de Wit J; Carr A, 2018, 'Hospitalisations over a year follow-up in a cohort of adults living with HIV with sustained viral suppression in Australia', presented at The Australasian HIV&AIDS Conference, Sydney, Australia, 24 September 2018 - 26 September 2018
    Conference Posters | 2018
    Siefried KJ; Mao L; Rule J; de Wit J; Carr A, 2018, 'Hospitalisations over a year follow-up in a cohort of adults living with HIV with sustained viral suppression in Australia', Amsterdam, the Netherlands, presented at 22nd International AIDS Conference, Amsterdam, the Netherlands, 23 July 2018 - 27 July 2018
    Conference Papers | 2017
    Siefried KJ; Mao L; Cysique LA; Rule J; Giles ML; Smith DE; McMahon J; Read TR; Ooi C; Tee BK; Bloch M; de Wit J; Carr A, 2017, 'Polypharmacy of concomitant medications in HIV-infected Australian adults is common, and associated with adverse effects', in Antiviral Therapy, International Medical Press, Milan, Italy, presented at The 19th International Workshop on Co-morbidities and Adverse Drug Reaction in HIV, Milan, Italy, 23 October 2017 - 25 October 2017
    Conference Posters | 2017
    Siefried KJ; Mao L; Cysique LA; Rule J; Giles ML; Smith DE; McMahon J; Read TR; Ooi C; Tee BK; Bloch M; de Wit J; Carr A, 2017, 'Polypharmacy of concomitant medications in HIV-infected Australian adults is common, and associated with adverse effects', Milan, Italy, presented at The 16th European AIDS Conference, Milan, Italy, 25 October 2017 - 27 October 2017
    Conference Presentations | 2017
    Siefried KJ; Mao L; Cysique LA; Rule J; Giles ML; Smith DE; McMahon J; Read TR; Ooi C; Tee BK; Bloch M; de wit J; Carr A, 2017, 'Polypharmacy of concomitant medications in HIV-infected Australian adults is common, and associated with adverse effects', presented at The Australasian HIV&AIDS Conference, Canberra Australia, 06 November 2017 - 08 November 2017
    Conference Posters | 2017
    Siefried KJ; Mao L; Richardson R; Kerr S; Rule J; McAllister J; Carr A, 2017, 'Socioeconomic and psychosocial factors are associated with suboptimal outcomes in HIV-infected adults: a case-control analysis', Canberra, Australia, presented at The Australasian HIV&AIDS Conference, Canberra, Australia, 06 November 2017 - 08 November 2017
    Conference Papers | 2017
    Siefried KJ; Mao L; Richardson R; Kerr S; Rule J; McAllister J; de Wit J; Carr A, 2017, 'Socioeconomic and psychosocial factors are associated with suboptimal outcomes in HIV-infected adults: a case-control analysis', in Antiviral Therapy, International Medical Press, Milan, Italy, presented at The 19th International Workshop on Co-morbidities and Adverse Drug Reaction in HIV, Milan, Italy, 23 October 2017 - 25 October 2017
    Conference Posters | 2017
    Siefried KJ; Mao L; Richardson R; Kerr S; Rule J; McAllister J; de Wit J; Carr A, 2017, 'Socioeconomic and psychosocial factors are associated with suboptimal outcomes in HIV-infected adults: a case-control analysis', Milan, Italy, presented at The 16th European AIDS Conference, Milan, Italy, 25 October 2017 - 27 October 2017
    Conference Papers | 2017
    Siefried KJ; Mao L; Riches R; Kerr S; Rule J; McAllister J; de Wit J; Carr A, 2017, 'Failure of antiretroviral therapy (ART) in Australian adults is mainly due to ART toxicity', in Antiviral Therapy, International Medical Press, Milan, Italy, presented at The 19th International Workshop on Co-morbidities and Adverse Drug Reaction in HIV, Milan, Italy, 23 October 2017 - 25 October 2017
    Conference Presentations | 2017
    Siefried KJ; Mao L; Riches S; Kerr S; Rule J; McAllister J; de Wit J; Carr A, 2017, 'Failure of antiretroviral therapy (ART) in Australian adults is mainly due to ART toxicity', presented at The Australasian HIV&AIDS Conference, Canberra, Australia, 06 November 2017 - 08 November 2017
    Conference Posters | 2017
    Siefried KJ; Mao L; Riches S; Kerr S; Rule J; McAllister J; de Wit J; Carr A, 2017, 'Failure of antiretroviral therapy (ART) in Australian adults is mainly due to ART toxicity', Milan, Italy, presented at The 16th European AIDS Conference, Milan, Italy, 25 October 2017 - 27 October 2017
    Conference Presentations | 2016
    Mao L; Siefried KJ; Carr A; de Wit J, 2016, 'Perceptions of TasP among HIV-positive gay men with sustained viral suppression', presented at 2016 Australasian HIV & AIDS Conference, Adelaide, 16 November 2016 - 18 November 2016
    Conference Papers | 2016
    Siefried KJ; Mao L; Kerr S; Gates T; Maynard A; Cysique LA; McAllister J; de Wit J; Carr A, 2016, 'Concomitant medication use in ART-experienced Australian adults: data from the PAART study', in Antiviral Therapy, International Medical Press, New York City, USA, presented at The 18th International Workshop on Co-morbidities and Adverse Drug Reactions in HIV, New York City, USA, 12 September 2016 - 13 September 2016
    Conference Presentations | 2016
    Siefried KJ; Mao L; Kerr S; Gates T; Maynard A; Cysique LA; McAllister J; de Wit J; Carr A, 2016, 'Concomitant medication use in ART-experienced adults: data from the PAART study', presented at The Australasian HIV&AIDS Conference, Adelaide, Australia, 16 November 2016 - 18 November 2016
    Conference Abstracts | 2016
    Siefried KJ; Mao L; Kerr S; Gates TM; Maynard A; Cysique LA; McAllister J; de Wit J; Carr A, 2016, 'Concomitant medication use in ART-experienced Australian adults: data from the PAART Study', in ANTIVIRAL THERAPY, INT MEDICAL PRESS LTD, NY, New York, Vol. 21, pp. A50 - A50, presented at 18th International Workshop on Co-Morbidities and Adverse Drug Reactions in HIV, NY, New York, 12 September 2016 - 13 September 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000389747500044&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Posters | 2015
    Gates T; Cysique LA; Chaganti J; Siefried KJ; Brew BJ, 2015, 'Maraviroc-enhanced CART improves cognition in virally suppressed HAND: a pilot study', Seattle, USA, presented at The 22nd Conference on Retroviruses and Opportunistic Infections (CROI), Seattle, USA, 23 February 2015 - 26 February 2015
    Conference Presentations | 2015
    Siefried KJ; Mao L; Kerr S; Gates T; Cysique LA; de Wit J; Carr A, 2015, 'Parameters associated with adherence to antiretroviral therapy in HIV-infected Australian adults: the PAART study', presented at The Australasian HIV&AIDS Conference, Brisbane, Australia, 16 September 2015 - 18 September 2015
    Conference Posters | 2014
    Siefried KJ; McAllister J; McNulty A; Read TR; Pearce A; Richardson R; Carr A, 2014, 'Safety and tolerability of, and adherence to, co-formulated emtricitabine-rilpivirine-tenofovir used as HIV non-occupational post-exposure prophylaxis in men who have sex with men', Sydney, Australia, presented at The St Vincent’s and Mater Health Research Symposium, Sydney, Australia, 11 September 2014 - 11 September 2014
    Conference Papers | 2013
    Lu G; Brew B; Siefried K; Draper B; Cysique L, 2013, 'Moderate neurocognitive decline can be detected over a four-month period using the HIV-dementia scale', in JOURNAL OF NEUROVIROLOGY, SPRINGER, DC, Washington, pp. S51 - S51, presented at 12th International Symposium on NeuroVirology, DC, Washington, 29 October 2013 - 02 November 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000325777200107&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Posters | 2013
    Lu G; Siefried KJ; Draper B; Brew BJ; Cysique LA, 2013, 'Moderate neurocognitive decline can be detected over a four-month period using the HIV-dementia scale (HDS)', Atlanta, USA, presented at The 20th Conference on Retroviruses and Opportunistic Infections (CROI), Atlanta, USA, 03 March 2013 - 06 March 2013
    Conference Posters | 2013
    Siefried KJ; Mao L; McAllister J; Richardson R; Watson J; de Wit J; Carr A, 2013, 'Predictors of adherence to antiretroviral therapy in HIV-infected adults (the PAART pilot study)', Darwin, Australia, presented at The Australasian HIV&AIDS Conference, Darwin, Australia, 21 October 2013 - 23 October 2013

NHMRC: $2,928,298

Other Public and Industry: $1,821,824

 

 

St Vincent’s Clinic Foundation Nursing Excellence Award

2016: Clinical Researcher on St Vincent’s Campus
 

Gilead Fellowship

2013-2014: Awarded for research on factors associated with suboptimal outcomes in antiretroviral therapy (CIA)

 

CIA: 

An open label trial of lisdexamfetamine for acute methamphetamine withdrawal - the OLAM study. ANZCTR: ACTRN12621000045819

Pharmacological treatment for methamphetamine withdrawal: a systematic review and meta-analysis of randomised controlled trials. Prospero: CRD42021224850

Exploring social and cultural aspects of GHB use among LGBTQ Australians. Further info

  • Established the National Methamphetamine and Emerging Drugs Clinical Research Network Working Group, engaging multi-disciplinary stakeholders to collaborate towards multi-centre clinical research
  • Developed, implemented and oversee the NCCRED seed funding grants, awarding over $2.7M in competitive funding over four rounds
  • Developed, implemented and oversee the NCCRED clinical research fellowships and scholarships programs, supporting 5 AOD clinical scholars to conduct research and contribute to UNSW through their adjunct positions
  • Active member of the:
    • St Vincent’s Hospital Alcohol and Drug Service Research Committee
    • NDARC Strategic Advisory Committee
    • St Vincent’s Health Sydney Inclusive Health Committee

My Research Supervision

PhD

Liam Acheson - Pharmacotherapy for adults during acute withdrawal from methamphetamine (Joint Supervisor with Michael Farrell)

Jack Freestone - Exploring sexualised drug use among LGBTQ populations and examining the impact of peer led interventions to address related harms (Co-Supervisor with Garrett Prestage and Mohamed Hammoud)

My Teaching

Current - UNSW Medicine Hons Project

Vincent Chauvet (2023) - Outcomes and measures used in research of psychedelic medications for mental health and addiction (Co-supervising with Jonathan Brett)

Sophie van der Helder (2023) - Co-designing psychedelic-facilitated psychotherapy studies with Australians with lived experience (Co-supervising with Jonathan Brett)

Completed - UNSW Medicine Hons Project

Keaton Buhagiar (First Class Hons) - Gamma-hydroxybutyrate cultures, experiences and practices in heterosexual cis and transgender people living in Australia (Co-supervised with Jonathan Brett) (2022)

Oliver Harris (First Class Hons) - Gamma-hydroxybutyrate overdose in inner-Sydney emergency departments: a retrospective review (Co-supervised with Jonathan Brett) (2021)

Completed - Notre Dame Medicine Year 2 Research Project

Rhiannon Lindsey - A retrospective audit of gamma-hydroxybutyrate (GHB) withdrawal in an inner-city Sydney hospital (Co-supervised with Jonathan Brett) (2022)

Completed - UNSW Medicine Year 4 Research Project

Amy Healey - Drug use at music festivals (Co-supervised with Jonathan Brett) (2020)

Angus Tolhurst-McKiernan - Methamphetamine use and its associations with insomnia and psychosis (Co-supervised with Nadine Ezard and Jonathan Brett) (2019) 

Clinical

Nursing preceptorships; Clinical Psychology Students (research supervision and clinical supervision); Nursing student supervision (clinical)